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Suzanne Thorpe

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Chemicals & Drugs

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Physiology

Lipid Peroxidation

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Yiqiang Zhang; Yuji Ikeno; Wenbo Qi; Asish Chaudhuri; Yan Li; Alex Bokov; Suzanne R Thorpe; John W Baynes; Charles Epstein; Arlan G Richardson; Holly Van Remmen
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.
Norma Frizzell; Mathur Rajesh; Matthew J Jepson; Ryoji Nagai; James A Carson; Suzanne R Thorpe; John W Baynes
Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin.
Per M Humpert; Ivan K Lukic; Suzanne R Thorpe; Stefan Hofer; Ezzat M Awad; Martin Andrassy; Elizabeth K Deemer; Michael Kasper; Erwin Schleicher; Markus Schwaninger; Markus A Weigand; Peter P Nawroth; Angelika Bierhaus
AGE-modified albumin containing infusion solutions boosts septicaemia and inflammation in experimental peritonitis.

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2009: Yiqiang Zhang; Yuji Ikeno; Wenbo Qi; Asish Chaudhuri; Yan Li; Alex Bokov; Suzanne R Thorpe; John W Baynes; Charles Epstein; Arlan G Richardson; Holly Van Remmen
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences 2009;64(12):1212-20.
2009: Norma Frizzell; Mathur Rajesh; Matthew J Jepson; Ryoji Nagai; James A Carson; Suzanne R Thorpe; John W Baynes
Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin.
The Journal of biological chemistry 2009;284(38):25772-81.
2009: Per M Humpert; Ivan K Lukic; Suzanne R Thorpe; Stefan Hofer; Ezzat M Awad; Martin Andrassy; Elizabeth K Deemer; Michael Kasper; Erwin Schleicher; Markus Schwaninger; Markus A Weigand; Peter P Nawroth; Angelika Bierhaus
AGE-modified albumin containing infusion solutions boosts septicaemia and inflammation in experimental peritonitis.
Journal of leukocyte biology 2009;86(3):589-97.
2008: Alicia J Jenkins; Michelle Rothen; Richard L Klein; Karina Moller; Leslie Eldridge; Deyi Zheng; Ramon Durazo-Arvizu; Daniel McGee; Daniel T Lackland; Suzanne R Thorpe; W Timothy Garvey; Timothy J Lyons
Cross-sectional associations of C-reactive protein with vascular risk factors and vascular complications in the DCCT/EDIC cohort.
Journal of diabetes and its complications 2008;22(3):153-63.
2008: Matthew Blatnik; Suzanne R Thorpe; John W Baynes
Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes.
Annals of the New York Academy of Sciences 2008;1126():272-5.
2008: Jonathan W C Brock; Alicia J Jenkins; Timothy J Lyons; Richard L Klein; Eunsil Yim; Maria F Lopes-Virella; Rickey Carter; Suzanne R Thorpe; John W Baynes
Increased methionine sulfoxide content of apoA-I in type 1 diabetes.
Journal of lipid research 2008;49(4):847-55.
2008: Michael Morcos; Xue-Liang Du; Friederike Pfisterer; Harald Hutter; Ahmed A R Sayed; Paul Thornalley; Naila Ahmed; John W Baynes; Suzanne R Thorpe; Georgi Kukudov; Andreas Schlotterer; Farastuk Bozorgmehr; Randa Abd El Baki; David M Stern; Frank Moehrlen; Youssef Ibrahim; Dimitrios Oikonomou; Andreas Hamann; Christian Becker; Martin Zeier; Vedat Schwenger; Nexhat Miftari; Per Humpert; Hans-Peter Hammes; Markus Buechler; Angelika Bierhaus; Michael Brownlee; Peter P Nawroth
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.
Aging cell 2008;7(2):260-9.
2008: Vicki Thallas; Suzanne R Thorpe; Melinda Coughlan; Kei Fukami; Felicia Y T Yap; Karly Sourris; Sally A Penfold; Leon A Bach; Mark E Cooper; Josephine M Forbes
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
Diabetes 2008;57(2):460-9.
2008: Matthew Blatnik; Norma Frizzell; Suzanne R Thorpe; John W Baynes
Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress.
Diabetes 2008;57(1):41-9.
2007: Ryoji Nagai; Jonathan W Brock; Matthew Blatnik; John E Baatz; Jennifer Rutherford Bethard; Michael D Walla; Suzanne R Thorpe; John W Baynes; Norma Frizzell
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
The Journal of biological chemistry 2007;282(47):34219-28.
2007: N C den Hollander; Douwe J Mulder; Reindert Graaff; Suzanne R Thorpe; John W Baynes; G Peter A Smit; Andries J Smit
Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia.
Journal of inherited metabolic disease 2007;30(6):916-23.
2007: Josephine V Glenn; J Renwick Beattie; Lindsay Barrett; Norma Frizzell; Suzanne R Thorpe; Mike E Boulton; John J McGarvey; Alan Stitt
Confocal Raman microscopy can quantify advanced glycation end product (AGE) modifications in Bruch's membrane leading to accurate, nondestructive prediction of ocular aging.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(13):3542-52.
2007: Melinda Coughlan; Vicki Thallas; Josefa Pete; David M Long; Anna Gasser; David C K Tong; Maryann Arnstein; Suzanne R Thorpe; Mark E Cooper; Josephine M Forbes
Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?
Endocrinology 2007;148(2):886-95.
2007: Jonathan W C Brock; Jennifer M Ames; Suzanne R Thorpe; John W Baynes
Formation of methionine sulfoxide during glycoxidation and lipoxidation of ribonuclease A.
Archives of biochemistry and biophysics 2007;457(2):170-6.
2007: Jonathan W C Brock; William E Cotham; Suzanne R Thorpe; John W Baynes; Jennifer M Ames
Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis.
Journal of mass spectrometry : JMS 2007;42(1):89-100.
2006: Y Yu; Suzanne R Thorpe; Alicia J Jenkins; J Nikki Shaw; Mark A Sochaski; Daniel McGee; C E Aston; T J Orchard; N Silvers; Y G Peng; J A McKnight; John W Baynes; Timothy J Lyons
Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes.
Diabetologia 2006;49(10):2488-98.
2006: Nathan L Alderson; Yuping Wang; Matthew Blatnik; Norma Frizzell; Michael D Walla; Timothy J Lyons; Nadja Alt; James A Carson; Ryoji Nagai; Suzanne R Thorpe; John W Baynes
S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.
Archives of biochemistry and biophysics 2006;450(1):1-8.
2005: Robbert Meerwaldt; Jasper W L Hartog; Reindert Graaff; Roel J Huisman; Thera P Links; Nynke C den Hollander; Suzanne R Thorpe; John W Baynes; gerjan navis; Rijk O B Gans; Andries J Smit
Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients.
Journal of the American Society of Nephrology : JASN 2005;16(12):3687-93.
2005: Femke Waanders; Wendela L Greven; John W Baynes; Suzanne R Thorpe; Andrea B Kramer; Ryoji Nagai; Noriyuki Sakata; Harry van Goor; gerjan navis
Renal accumulation of pentosidine in non-diabetic proteinuria-induced renal damage in rats.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(10):2060-70.
2005: Josephine M Forbes; Suzanne R Thorpe; Vicki Thallas; Josefa Pete; Merlin C Thomas; Elizabeth R Deemer; Sahar Bassal; Assam El-Osta; David M Long; Sianna Panagiotopoulos; George Jerums; Tanya M Osicka; Mark E Cooper
Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2005;16(8):2363-72.
2005: Andrzej Januszewski; Nathan L Alderson; Alicia J Jenkins; Suzanne R Thorpe; John W Baynes
Chemical modification of proteins during peroxidation of phospholipids.
Journal of lipid research 2005;46(7):1440-9.
2005: Sarah M Brown; Della M Smith; Nadja Alt; Suzanne R Thorpe; John W Baynes
Tissue-specific variation in glycation of proteins in diabetes: evidence for a functional role of amadoriase enzymes.
Annals of the New York Academy of Sciences 2005;1043():817-23.
2005: Veronika Somoza; Michael Lindenmeier; Thomas Hofmann; Oliver Frank; Helmut F Erbersdobler; John W Baynes; Suzanne R Thorpe; August Heidland; Holger Zill; Stephan Bek; Jochen Huber; Thomas Weigle; Sabine Scheidler; Andreas E Busch; Katarína Sebeková
Dietary bread crust advanced glycation end products bind to the receptor for AGEs in HEK-293 kidney cells but are rapidly excreted after oral administration to healthy and subtotally nephrectomized rats.
Annals of the New York Academy of Sciences 2005;1043():492-500.
2005: Katarína Sebeková; Thomas Hofmann; Peter Boor; Katarína Sebeková; Ol'ga Ulicná; Helmut F Erbersdobler; John W Baynes; Suzanne R Thorpe; August Heidland; Veronika Somoza
Renal effects of oral maillard reaction product load in the form of bread crusts in healthy and subtotally nephrectomized rats.
Annals of the New York Academy of Sciences 2005;1043():482-91.
2005: Andrzej Januszewski; Alicia J Jenkins; John W Baynes; Suzanne R Thorpe
Lipid-derived modifications of plasma proteins in experimental and human diabetes.
Annals of the New York Academy of Sciences 2005;1043():404-12.
2005: Richard L Klein; Andrea J Semler; John W Baynes; Suzanne R Thorpe; Timothy J Lyons; Alicia J Jenkins
Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells.
Annals of the New York Academy of Sciences 2005;1043():379-89.
2005: Maria F Lopes-Virella; Suzanne R Thorpe; M Brooks Derrick; Charlyne Chassereau; Gabriel Virella
The immunogenicity of modified lipoproteins.
Annals of the New York Academy of Sciences 2005;1043():367-78.
2005: Robbert Meerwaldt; Thera P Links; Reindert Graaff; Suzanne R Thorpe; John W Baynes; Jasper W L Hartog; Rijk O B Gans; Andries Smit
Simple noninvasive measurement of skin autofluorescence.
Annals of the New York Academy of Sciences 2005;1043():290-8.
2005: J W C Brock; William E Cotham; Jennifer M Ames; Suzanne R Thorpe; John W Baynes
Proteomic method for the quantification of methionine sulfoxide.
Annals of the New York Academy of Sciences 2005;1043():284-9.
2005: Ryoji Nagai; Elizabeth K Deemer; Jonathan W Brock; Suzanne R Thorpe; John W Baynes
Effect of glucose concentration on formation of AGEs in erythrocytes in vitro.
Annals of the New York Academy of Sciences 2005;1043():146-50.
2005: M C Thomas; John W Baynes; Suzanne R Thorpe; M E Cooper
The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.
Current drug targets 2005;6(4):453-74.
2005: Alan Stitt; Ciara McGoldrick; Aine Rice-McCaldin; David R McCance; Josephine V Glenn; Daniel K Hsu; Fu-Tong Liu; Suzanne R Thorpe; Tom A Gardiner
Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3.
Diabetes 2005;54(3):785-94.
2005: Gabriel Virella; M Brooks Derrick; Virginia Pate; Charlyne Chassereau; Suzanne R Thorpe; Maria F Lopes-Virella
Development of capture assays for different modifications of human low-density lipoprotein.
Clinical and diagnostic laboratory immunology 2005;12(1):68-75.
2004: William E Cotham; Tom Metz; Lee Ferguson; Jonathan W C Brock; Davinia J S Hinton; Suzanne R Thorpe; John W Baynes; Jennifer M Ames
Proteomic analysis of arginine adducts on glyoxal-modified ribonuclease.
Molecular & cellular proteomics : MCP 2004;3(12):1145-53.
2004: Josephine M Forbes; Merlin C Thomas; Suzanne R Thorpe; Nathan L Alderson; Mark E Cooper
The effects of valsartan on the accumulation of circulating and renal advanced glycation end products in experimental diabetes.
Kidney international. Supplement 2004;(92):S105-7.
2004: Alan Stitt; S-J Hughes; Paul Canning; O Lynch; O Cox; Norma Frizzell; Suzanne R Thorpe; T G Cotter; Tim M Curtis; Tom A Gardiner
Substrates modified by advanced glycation end-products cause dysfunction and death in retinal pericytes by reducing survival signals mediated by platelet-derived growth factor.
Diabetologia 2004;47(10):1735-46.
2004: Gabriel Virella; Suzanne R Thorpe; Nathan L Alderson; M Brooks Derrick; Charlyne Chassereau; J Matthew Rhett; Maria F Lopes-Virella
Definition of the immunogenic forms of modified human LDL recognized by human autoantibodies and by rabbit hyperimmune antibodies.
Journal of lipid research 2004;45(10):1859-67.
2004: Nathan L Alderson; Mark E Chachich; Norma Frizzell; Paul Canning; Tom Metz; Andrzej Januszewski; N N Youssef; Alan Stitt; John W Baynes; Suzanne R Thorpe
Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat.
Diabetologia 2004;47(8):1385-95.
2004: Alicia J Jenkins; Suzanne R Thorpe; Nathan L Alderson; Kathie L Hermayer; Timothy J Lyons; Lowrey P King; Charlyne Chassereau; Richard L Klein
In vivo glycated low-density lipoprotein is not more susceptible to oxidation than nonglycated low-density lipoprotein in type 1 diabetes.
Metabolism: clinical and experimental 2004;53(8):969-76.
2004: Robbert Meerwaldt; Reindert Graaff; P H N Oomen; Thera P Links; JJ Jager; Nathan L Alderson; Suzanne R Thorpe; John W Baynes; Rijk O B Gans; Andries J Smit
Simple non-invasive assessment of advanced glycation endproduct accumulation.
Diabetologia 2004;47(7):1324-30.
2004: Josephine M Forbes; Louis Teo Loon Yee; Vicki Thallas; Markus Lassila; Riccardo Candido; Karin A Jandeleit-Dahm; Merlin C Thomas; Wendy C Burns; Elizabeth K Deemer; Suzanne R Thorpe; Susan M Thorpe; Mark E Cooper; Terri J Allen
Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis.
Diabetes 2004;53(7):1813-23.
2004: Nadja Alt; James A Carson; Nathan L Alderson; Yuping Wang; Ryoji Nagai; Thomas Henle; Suzanne R Thorpe; John W Baynes
Chemical modification of muscle protein in diabetes.
Archives of biochemistry and biophysics 2004;425(2):200-6.
2004: Alan Stitt; Norma Frizzell; Suzanne R Thorpe
Advanced glycation and advanced lipoxidation: possible role in initiation and progression of diabetic retinopathy.
Current pharmaceutical design 2004;10(27):3349-60.
2003: Holly Van Remmen; Yuji Ikeno; Michelle Hamilton; Mohammad Pahlavani; Norman Wolf; Suzanne R Thorpe; Nathan L Alderson; John W Baynes; Charles J Epstein; Ting-Ting Huang; James Nelson; John Strong; Arlan G Richardson
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.
Physiological genomics 2003;16(1):29-37.
2003: Suzanne R Thorpe; John W Baynes
Maillard reaction products in tissue proteins: new products and new perspectives.
Amino acids 2003;25(3-4):275-81.
2003: William E Cotham; Davinia J S Hinton; Tom Metz; J W C Brock; Suzanne R Thorpe; John W Baynes; J M Ames
Mass spectrometric analysis of glucose-modified ribonuclease.
Biochemical Society transactions 2003;31(Pt 6):1426-7.
2003: Andrzej Januszewski; Nathan L Alderson; Tom Metz; Suzanne R Thorpe; John W Baynes
Role of lipids in chemical modification of proteins and development of complications in diabetes.
Biochemical Society transactions 2003;31(Pt 6):1413-6.
2003: Tom Metz; Nathan L Alderson; Suzanne R Thorpe; John W Baynes
Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications.
Archives of biochemistry and biophysics 2003;419(1):41-9.
2003: Tom Metz; Nathan L Alderson; Mark E Chachich; Suzanne R Thorpe; John W Baynes
Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications.
The Journal of biological chemistry 2003;278(43):42012-9.
2003: Jonathan W C Brock; Davinia J S Hinton; William E Cotham; Tom Metz; Suzanne R Thorpe; John W Baynes; Jennifer M Ames
Proteomic analysis of the site specificity of glycation and carboxymethylation of ribonuclease.
Journal of proteome research 2003;2(5):506-13.
2003: Tom A Gardiner; H R Anderson; Thorsten P Degenhardt; Suzanne R Thorpe; John W Baynes; Desmond B Archer; Alan Stitt
Prevention of retinal capillary basement membrane thickening in diabetic dogs by a non-steroidal anti-inflammatory drug.
Diabetologia 2003;46(9):1269-75.
2003: Nathan L Alderson; Mark E Chachich; Nancy N Youssef; Robert J Beattie; Maurice Nachtigal; Suzanne R Thorpe; John W Baynes
The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats.
Kidney international 2003;63(6):2123-33.
2003: Gabriel Virella; Suzanne R Thorpe; Nathan L Alderson; Elias M Stephan; Daniel Atchley; Francesco Wagner; Maria F Lopes-Virella
Autoimmune response to advanced glycosylation end-products of human LDL.
Journal of lipid research 2003;44(3):487-93.
2002: Alan Stitt; Tom A Gardiner; Nathan L Alderson; Paul Canning; Norma Frizzell; Noel Duffy; Cliona Boyle; Andrzej Januszewski; Mark E Chachich; John W Baynes; Suzanne R Thorpe; Nathan L Anderson
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
Diabetes 2002;51(9):2826-32.
2002: Mark A Sochaski; Wally J Bartfay; Suzanne R Thorpe; John W Baynes; Emma Bartfay; Denis C Lehotay; Peter P Liu
Lipid peroxidation and protein modification in a mouse model of chronic iron overload.
Metabolism: clinical and experimental 2002;51(5):645-51.
2002: Thorsten P Degenhardt; Nathan L Alderson; David D Arrington; Robert J Beattie; John M Basgen; Michael W Steffes; Suzanne R Thorpe; John W Baynes
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.
Kidney international 2002;61(3):939-50.
2002: J Nikki Shaw; John W Baynes; Suzanne R Thorpe
N epsilon-(carboxymethyl)lysine (CML) as a biomarker of oxidative stress in long-lived tissue proteins.
Methods in molecular biology (Clifton, N.J.) 2002;186():129-37.
2002: Nicole Verzijl; Jeroen DeGroot; Zaken Chaya Ben; Orit Brau-Benjamin; Alice Maroudas; Ruud A Bank; Joseph Mizrahi; Casper G Schalkwijk; Suzanne R Thorpe; John W Baynes; J W J Bijlsma; Floris P J G Lafeber; Johan teKoppele
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
Arthritis and rheumatism 2002;46(1):114-23.
2001: D L Price; P M Rhett; Suzanne R Thorpe; John W Baynes
Chelating activity of advanced glycation end-product inhibitors.
The Journal of biological chemistry 2001;276(52):48967-72.
2001: Mark A Sochaski; Alicia J Jenkins; Timothy J Lyons; Suzanne R Thorpe; John W Baynes
Isotope dilution gas chromatography/mass spectrometry method for the determination of methionine sulfoxide in protein.
Analytical chemistry 2001;73(19):4662-7.
2000: Nicole Verzijl; Jeroen DeGroot; Suzanne R Thorpe; Ruud A Bank; J Nikki Shaw; Timothy J Lyons; J W J Bijlsma; Floris P J G Lafeber; John W Baynes; Johan teKoppele
Effect of collagen turnover on the accumulation of advanced glycation end products.
The Journal of biological chemistry 2000;275(50):39027-31.
2000: Nicole Verzijl; Jeroen DeGroot; E Oldehinkel; Ruud A Bank; Suzanne R Thorpe; John W Baynes; MT Bayliss; J W J Bijlsma; Floris P J G Lafeber; Johan teKoppele
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
The Biochemical journal 2000;350 Pt 2():381-7.
2000: JM Onorato; A J Jenkins; Suzanne R Thorpe; John W Baynes
Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine.
The Journal of biological chemistry 2000;275(28):21177-84.
2000: John W Baynes; Suzanne R Thorpe
Glycoxidation and lipoxidation in atherogenesis.
Free radical biology & medicine 2000;28(12):1708-16.
2000: Reinald Pamplona; Manuel Portero-Otín; D Riba; Jesús R Requena; Suzanne R Thorpe; Mónica López-Torres; Gustavo Barja
Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(6):B286-91.
2000: Gabriel Virella; Sinikka Koskinen; Gregor Krings; JM Onorato; Suzanne R Thorpe; Maria F Lopes-Virella
Immunochemical characterization of purified human oxidized low-density lipoprotein antibodies.
Clinical immunology (Orlando, Fla.) 2000;95(2):135-44.
2000: Catherine C Hedrick; Suzanne R Thorpe; MX Fu; C M Harper; J Yoo; S M Kim; H Wong; A L Peters
Glycation impairs high-density lipoprotein function.
Diabetologia 2000;43(3):312-20.
2000: J R Requena; Suzanne R Thorpe; D L Price; John W Baynes
Measurement of pentosidine in biological samples.
Methods in molecular medicine 2000;38():209-17.
1999: J E Litchfield; Suzanne R Thorpe; John W Baynes
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo.
The international journal of biochemistry & cell biology 1999;31(11):1297-305.
1999: Reinald Pamplona; Manuel Portero-Otín; C Ruiz; Maria Josep Bellmunt; Jesús R Requena; Suzanne R Thorpe; John W Baynes; M Romero; Mónica López-Torres; Gustavo Barja
Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins.
Free radical biology & medicine 1999;27(7-8):901-10.
1999: Alicia J Jenkins; W Li; K Moller; Richard L Klein; MX Fu; John W Baynes; Suzanne R Thorpe; Timothy J Lyons
Pre-enrichment of modified low density lipoproteins with alpha-tocopherol mitigates adverse effects on cultured retinal capillary cells.
Current eye research 1999;19(2):137-45.
1999: W C Fountain; JR Requena; Alicia J Jenkins; Timothy J Lyons; B Smyth; John W Baynes; Suzanne R Thorpe
Quantification of N-(glucitol)ethanolamine and N-(carboxymethyl)serine: two products of nonenzymatic modification of aminophospholipids formed in vivo.
Analytical biochemistry 1999;272(1):48-55.
1999: Martin M Anderson; J R Requena; Jan R Crowley; Suzanne R Thorpe; Jay W Heinecke
The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation.
The Journal of clinical investigation 1999;104(1):103-13.
1999: Thorsten P Degenhardt; MX Fu; E Voss; K Reiff; R Neidlein; K Strein; Suzanne R Thorpe; John W Baynes; R Reiter
Aminoguanidine inhibits albuminuria, but not the formation of advanced glycation end-products in skin collagen of diabetic rats.
Diabetes research and clinical practice 1999;43(2):81-9.
1999: Reinald Pamplona; Manuel Portero-Otín; Jesús R Requena; Suzanne R Thorpe; A Herrero; Gustavo Barja
A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation-derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat.
Mechanisms of ageing and development 1999;106(3):283-96.
1999: John W Baynes; Suzanne R Thorpe
Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.
Diabetes 1999;48(1):1-9.
1998: JM Onorato; Suzanne R Thorpe; John W Baynes
Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease.
Annals of the New York Academy of Sciences 1998;854():277-90.
1998: Thorsten P Degenhardt; Suzanne R Thorpe; John W Baynes
Chemical modification of proteins by methylglyoxal.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(7):1139-45.
1998: Toshio Miyata; MX Fu; Kiyoshi Kurokawa; Charles van Ypersele de Strihou; Suzanne R Thorpe; John W Baynes
Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: is there oxidative stress in uremia?
Kidney international 1998;54(4):1290-5.
1998: Reinald Pamplona; Jesús R Requena; Manuel Portero-Otín; Joan Prat; Suzanne R Thorpe; Maria Josep Bellmunt
Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals--evidence for intracellular lipid glycoxidation.
European journal of biochemistry / FEBS 1998;255(3):685-9.
1998: E B Frye; Thorsten P Degenhardt; Suzanne R Thorpe; John W Baynes
Role of the Maillard reaction in aging of tissue proteins. Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins.
The Journal of biological chemistry 1998;273(30):18714-9.
1998: M Shinohara; Paul J Thornalley; Ida Giardino; Paul J Beisswenger; Suzanne R Thorpe; JM Onorato; Michael Brownlee
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
The Journal of clinical investigation 1998;101(5):1142-7.
1998: S Fu; MX Fu; John W Baynes; Suzanne R Thorpe; Roger T Dean
Presence of dopa and amino acid hydroperoxides in proteins modified with advanced glycation end products (AGEs): amino acid oxidation products as a possible source of oxidative stress induced by AGE proteins.
The Biochemical journal 1998;330 ( Pt 1)():233-9.
1997: Thorsten P Degenhardt; L Grass; S Reddy; Suzanne R Thorpe; E P Diamandis; John W Baynes
Technical note. The serum concentration of the advanced glycation end-product N epsilon-(carboxymethyl)lysine is increased in uremia.
Kidney international 1997;52(4):1064-7.
1997: Rhona Stein; David M Goldenberg; G L Ong; Suzanne R Thorpe; M Jules Mattes
Manipulation of blood clearance to optimize delivery of residualizing label-antibody conjugates to tumor cells in vivo.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(9):1392-400.
1997: M C Wells-Knecht; Timothy J Lyons; D R McCance; Suzanne R Thorpe; John W Baynes
Age-dependent increase in ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes. Evidence against a generalized increase in oxidative stress in diabetes.
The Journal of clinical investigation 1997;100(4):839-46.
1997: JR Requena; MU Ahmed; C W Fountain; Thorsten P Degenhardt; S Reddy; C Perez; Timothy J Lyons; Alicia J Jenkins; John W Baynes; Suzanne R Thorpe
Carboxymethylethanolamine, a biomarker of phospholipid modification during the maillard reaction in vivo.
The Journal of biological chemistry 1997;272(28):17473-9.
1997: MU Ahmed; E Brinkmann Frye; Thorsten P Degenhardt; Suzanne R Thorpe; John W Baynes
N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins.
The Biochemical journal 1997;324 ( Pt 2)():565-70.
1997: Rhona Stein; David M Goldenberg; Suzanne R Thorpe; M Jules Mattes
Advantage of a residualizing iodine radiolabel for radioimmunotherapy of xenografts of human non-small-cell carcinoma of the lung.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(3):391-5.
1997: JR Requena; MX Fu; MU Ahmed; Alicia J Jenkins; Timothy J Lyons; John W Baynes; Suzanne R Thorpe
Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein.
The Biochemical journal 1997;322 ( Pt 1)():317-25.
1996: Suzanne R Thorpe; John W Baynes
Role of the Maillard reaction in diabetes mellitus and diseases of aging.
Drugs & aging 1996;9(2):69-77.
1996: MX Fu; J R Requena; Alicia J Jenkins; Timothy J Lyons; John W Baynes; Suzanne R Thorpe
The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions.
The Journal of biological chemistry 1996;271(17):9982-6.
1996: J R Requena; MX Fu; M U Ahmed; Alicia J Jenkins; Timothy J Lyons; Suzanne R Thorpe
Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1996;11 Suppl 5():48-53.
1996: K J Wells-Knecht; E Brinkmann; M C Wells-Knecht; J E Litchfield; M U Ahmed; S Reddy; D V Zyzak; Suzanne R Thorpe; John W Baynes
New biomarkers of Maillard reaction damage to proteins.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1996;11 Suppl 5():41-7.
1995: M C Wells-Knecht; Suzanne R Thorpe; John W Baynes
Pathways of formation of glycoxidation products during glycation of collagen.
Biochemistry 1995;34(46):15134-41.
1995: William T Cefalu; Audrey D Bell-Farrow; Zhong Q Wang; William E Sonntag; MX Fu; John W Baynes; Suzanne R Thorpe
Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen.
The journals of gerontology. Series A, Biological sciences and medical sciences 1995;50(6):B337-41.
1995: S Reddy; J Bichler; K J Wells-Knecht; Suzanne R Thorpe; John W Baynes
N epsilon-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins.
Biochemistry 1995;34(34):10872-8.
1995: R Stein; David M Goldenberg; Suzanne R Thorpe; A Basu; M Jules Mattes
Effects of radiolabeling monoclonal antibodies with a residualizing iodine radiolabel on the accretion of radioisotope in tumors.
Cancer research 1995;55(14):3132-9.
1995: Z C Chroneos; John W Baynes; Suzanne R Thorpe
Identification of liver endothelial cells as the primary site of IgM catabolism in the rat.
Archives of biochemistry and biophysics 1995;319(1):63-73.
1995: K J Wells-Knecht; D V Zyzak; J E Litchfield; Suzanne R Thorpe; John W Baynes
Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose.
Biochemistry 1995;34(11):3702-9.
1995: D V Zyzak; J M Richardson; Suzanne R Thorpe; John W Baynes
Formation of reactive intermediates from Amadori compounds under physiological conditions.
Archives of biochemistry and biophysics 1995;316(1):547-54.
1994: J R Baker; D V Zyzak; Suzanne R Thorpe; John W Baynes
Chemistry of the fructosamine assay: D-glucosone is the product of oxidation of Amadori compounds.
Clinical chemistry 1994;40(10):1950-5.
1994: K J Wells-Knecht; Timothy J Lyons; D R McCance; Suzanne R Thorpe; M S Feather; John W Baynes
3-Deoxyfructose concentrations are increased in human plasma and urine in diabetes.
Diabetes 1994;43(9):1152-6.
1994: LB Shih; Suzanne R Thorpe; Gary L Griffiths; H Diril; GL Ong; Hans J Hansen; David M Goldenberg; M Jules Mattes
The processing and fate of antibodies and their radiolabels bound to the surface of tumor cells in vitro: a comparison of nine radiolabels.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(5):899-908.
1994: MX Fu; K J Wells-Knecht; J A Blackledge; Timothy J Lyons; Suzanne R Thorpe; John W Baynes
Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction.
Diabetes 1994;43(5):676-83.
1994: Suzanne R Thorpe; John W Baynes
Residualizing glycoconjugates: biologically inert tracers for studies on protein endocytosis and catabolism.
Methods in enzymology 1994;242():3-17.
1993: J Bichler; John W Baynes; Suzanne R Thorpe
Catabolism of hirudin and thrombin-hirudin complexes in the rat.
The Biochemical journal 1993;296 ( Pt 3)():771-6.
1993: J R Baker; D V Zyzak; Suzanne R Thorpe; John W Baynes
Mechanism of fructosamine assay: evidence against role of superoxide as intermediate in nitroblue tetrazolium reduction.
Clinical chemistry 1993;39(12):2460-5.
1993: M C Wells-Knecht; T G Huggins; D G Dyer; Suzanne R Thorpe; John W Baynes
Oxidized amino acids in lens protein with age. Measurement of o-tyrosine and dityrosine in the aging human lens.
The Journal of biological chemistry 1993;268(17):12348-52.
1993: T G Huggins; M C Wells-Knecht; N A Detorie; John W Baynes; Suzanne R Thorpe
Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation.
The Journal of biological chemistry 1993;268(17):12341-7.
1993: D R McCance; D G Dyer; J A Dunn; K E Bailie; Suzanne R Thorpe; John W Baynes; Timothy J Lyons
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
The Journal of clinical investigation 1993;91(6):2470-8.
1993: D G Dyer; J A Dunn; Suzanne R Thorpe; K E Bailie; Timothy J Lyons; D R McCance; John W Baynes
Accumulation of Maillard reaction products in skin collagen in diabetes and aging.
The Journal of clinical investigation 1993;91(6):2463-9.
1993: Suzanne R Thorpe; John W Baynes; Z C Chroneos
The design and application of residualizing labels for studies of protein catabolism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(5):399-405.
1993: D Potter; Z C Chroneos; John W Baynes; Peter R Sinclair; Nadia Gorman; H H Liem; U Muller-Eberhard; Suzanne R Thorpe
In vivo fate of hemopexin and heme-hemopexin complexes in the rat.
Archives of biochemistry and biophysics 1993;300(1):98-104.
1992: T G Huggins; M W Staton; D G Dyer; N J Detorie; Michael D Walla; John W Baynes; Suzanne R Thorpe
o-Tyrosine and dityrosine concentrations in oxidized proteins and lens proteins with age.
Annals of the New York Academy of Sciences 1992;663():436-7.
1992: D G Dyer; J A Dunn; Suzanne R Thorpe; Timothy J Lyons; D R McCance; John W Baynes
Accumulation of Maillard reaction products in skin collagen in diabetes and aging.
Annals of the New York Academy of Sciences 1992;663():421-2.
1992: MX Fu; K J Knecht; Suzanne R Thorpe; John W Baynes
Role of oxygen in cross-linking and chemical modification of collagen by glucose.
Diabetes 1992;41 Suppl 2():42-8.
1992: L A Meeh; Joseph J H Ackerman; Suzanne R Thorpe; A Daugherty
Quantification of the accumulation and degradation of beta-very-low-density lipoproteins in vivo using a 19F-containing residualizing label and n.m.r. spectroscopy.
The Biochemical journal 1992;286 ( Pt 3)():785-92.
1992: M M Dowd; John W Baynes; Suzanne R Thorpe
Synthesis of N,N-dilactitol ethylenediamine: a versatile spacer for attachment of residualizing labels to protein.
Analytical biochemistry 1992;205(2):369-71.
1992: J M Ord; J Hasapes; A Daugherty; Suzanne R Thorpe; Steven Bergmann; B E Sobel
Imaging of thrombi with tissue-type plasminogen activator rendered enzymatically inactive and conjugated to a residualizing label.
Circulation 1992;85(1):288-97.
1991: D G Dyer; J A Blackledge; Suzanne R Thorpe; John W Baynes
Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo.
The Journal of biological chemistry 1991;266(18):11654-60.
1991: J A Dunn; D R McCance; Suzanne R Thorpe; T J Lyons; John W Baynes
Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen.
Biochemistry 1991;30(5):1205-10.
1991: K J Knecht; J A Dunn; K F McFarland; D R McCance; Timothy J Lyons; Suzanne R Thorpe; John W Baynes
Effect of diabetes and aging on carboxymethyllysine levels in human urine.
Diabetes 1991;40(2):190-6.
1991: D G Dyer; J A Blackledge; B M Katz; C J Hull; H D Adkisson; Suzanne R Thorpe; Timothy J Lyons; John W Baynes
The Maillard reaction in vivo.
Zeitschrift für Ernährungswissenschaft 1991;30(1):29-45.
1991: Sylvie demignot; M V Pimm; Suzanne R Thorpe; R W Baldwin
Differences between the catabolism and tumour distribution of intact monoclonal antibody (791T/36) and its Fab/c fragment in mice with tumour xenografts revealed by the use of a residualizing radiolabel (dilactitol-125I-tyramine) and autoradiography.
Cancer immunology, immunotherapy : CII 1991;33(6):359-66.
1990: J A Dunn; M U Ahmed; M H Murtiashaw; J M Richardson; Michael D Walla; Suzanne R Thorpe; John W Baynes
Reaction of ascorbate with lysine and protein under autoxidizing conditions: formation of N epsilon-(carboxymethyl)lysine by reaction between lysine and products of autoxidation of ascorbate.
Biochemistry 1990;29(49):10964-70.
1990: Zina Moldoveanu; I Moro; J Radl; Suzanne R Thorpe; K Komiyama; Jiri Mestecky
Site of catabolism of autologous and heterologous IgA in non-human primates.
Scandinavian journal of immunology 1990;32(6):577-83.
1990: J L Maxwell; L Terracio; Thomas Keith Borg; John W Baynes; Suzanne R Thorpe
A fluorescent residualizing label for studies on protein uptake and catabolism in vivo and in vitro.
The Biochemical journal 1990;267(1):155-62.
1990: K L Lucas; John W Baynes; Suzanne R Thorpe
Intracellular processing of residualizing labels in different cell types in vitro.
Journal of cellular physiology 1990;142(3):581-5.
1990: J S Patrick; Suzanne R Thorpe; John W Baynes
Nonenzymatic glycosylation of protein does not increase with age in normal human lenses.
Journal of gerontology 1990;45(1):B18-23.
1989: A Daugherty; N N Becker; L A Scherrer; B E Sobel; Joseph J H Ackerman; John W Baynes; Suzanne R Thorpe
Non-invasive detection of protein metabolism in vivo by n.m.r. spectroscopy. Application of a novel 19F-containing residualizing label.
The Biochemical journal 1989;264(3):829-35.
1989: J A Dunn; J S Patrick; Suzanne R Thorpe; John W Baynes
Oxidation of glycated proteins: age-dependent accumulation of N epsilon-(carboxymethyl)lysine in lens proteins.
Biochemistry 1989;28(24):9464-8.
1989: John W Baynes; N G Watkins; C I Fisher; C J Hull; J S Patrick; M U Ahmed; J A Dunn; Suzanne R Thorpe
The Amadori product on protein: structure and reactions.
Progress in clinical and biological research 1989;304():43-67.
1989: Jiri Mestecky; Zina Moldoveanu; Milan Tomana; J M Epps; Suzanne R Thorpe; JO Phillips; R Kulhavy
The role of the liver in catabolism of mouse and human IgA.
Immunological investigations 1989;18(1-4):313-24.
1988: J L Maxwell; John W Baynes; Suzanne R Thorpe
Inulin-125I-tyramine, an improved residualizing label for studies on sites of catabolism of circulating proteins.
The Journal of biological chemistry 1988;263(28):14122-7.
1988: Zina Moldoveanu; J M Epps; Suzanne R Thorpe; Jiri Mestecky
The sites of catabolism of murine monomeric IgA.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(1):208-13.
1988: M U Ahmed; J A Dunn; Michael D Walla; Suzanne R Thorpe; John W Baynes
Oxidative degradation of glucose adducts to protein. Formation of 3-(N epsilon-lysino)-lactic acid from model compounds and glycated proteins.
The Journal of biological chemistry 1988;263(18):8816-21.
1988: John W Baynes; J L Maxwell; K M Rahman; Suzanne R Thorpe
Purification of residualizing glycoconjugate labels for protein by reversed-phase high-pressure liquid chromatography.
Analytical biochemistry 1988;170(2):382-6.
1987: N G Watkins; C I Neglia-Fisher; D G Dyer; Suzanne R Thorpe; John W Baynes
Effect of phosphate on the kinetics and specificity of glycation of protein.
The Journal of biological chemistry 1987;262(15):7207-12.
1986: J L Strobel; S G Cady; Thomas Keith Borg; L Terracio; John W Baynes; Suzanne R Thorpe
Identification of fibroblasts as a major site of albumin catabolism in peripheral tissues.
The Journal of biological chemistry 1986;261(17):7989-94.
1986: M U Ahmed; Suzanne R Thorpe; John W Baynes
Identification of N epsilon-carboxymethyllysine as a degradation product of fructoselysine in glycated protein.
The Journal of biological chemistry 1986;261(11):4889-94.
1985: A Daugherty; Suzanne R Thorpe; L G Lange; B E Sobel; G Schonfeld
Loci of catabolism of beta-very low density lipoprotein in vivo delineated with a residualizing label, 125I-dilactitol tyramine.
The Journal of biological chemistry 1985;260(27):14564-70.
1985: N G Watkins; Suzanne R Thorpe; John W Baynes
Glycation of amino groups in protein. Studies on the specificity of modification of RNase by glucose.
The Journal of biological chemistry 1985;260(19):10629-36.
1985: J L Strobel; John W Baynes; Suzanne R Thorpe
125I-glycoconjugate labels for identifying sites of protein catabolism in vivo: effect of structure and chemistry of coupling to protein on label entrapment in cells after protein degradation.
Archives of biochemistry and biophysics 1985;240(2):635-45.
1985: C I Neglia; H J Cohen; A R Garber; Suzanne R Thorpe; John W Baynes
Characterization of glycated proteins by 13C NMR spectroscopy. Identification of specific sites of protein modification by glucose.
The Journal of biological chemistry 1985;260(9):5406-10.
1984: A L Strickland; K F McFarland; M H Murtiashaw; Suzanne R Thorpe; John W Baynes
Changes in blood protein glycosylation during a diabetes summer camp.
Diabetes care 1984;7(2):183-5.
1984: John W Baynes; Suzanne R Thorpe; M H Murtiashaw
Nonenzymatic glucosylation of lysine residues in albumin.
Methods in enzymology 1984;106():88-98.
1983: C I Neglia; H J Cohen; A R Garber; P D Ellis; Suzanne R Thorpe; John W Baynes
13C NMR investigation of nonenzymatic glucosylation of protein. Model studies using RNase A.
The Journal of biological chemistry 1983;258(23):14279-83.
1983: M H Murtiashaw; Suzanne R Thorpe; John W Baynes
Determination of the specific activity of NaB3H4.
Analytical biochemistry 1983;135(2):443-6.
1983: J S Rush; Suzanne R Thorpe; John W Baynes
A rapid micro-modification of the quantitative immunoprecipitation assay.
Journal of immunological methods 1983;62(2):247-55.
1983: A S Eble; Suzanne R Thorpe; John W Baynes
Nonenzymatic glucosylation and glucose-dependent cross-linking of protein.
The Journal of biological chemistry 1983;258(15):9406-12.
1983: M H Murtiashaw; John W Baynes; Suzanne R Thorpe
Albumin catabolism in diabetic rats.
Archives of biochemistry and biophysics 1983;225(1):256-62.
1983: M H Murtiashaw; J E Young; A L Strickland; K F McFarland; Suzanne R Thorpe; John W Baynes
Measurement of nonenzymatically glucosylated serum protein by an improved thiobarbituric acid assay.
Clinica chimica acta; international journal of clinical chemistry 1983;130(2):177-87.
1982: L A Henderson; John W Baynes; Suzanne R Thorpe
Identification of the sites of IgG catabolism in the rat.
Archives of biochemistry and biophysics 1982;215(1):1-11.
1981: S Morrone; P G Pentchev; John W Baynes; Suzanne R Thorpe
Studies in vivo of the tissue uptake, cellular distribution and catabolic turnover of exogenous glucocerebrosidase in rat.
The Biochemical journal 1981;194(3):733-42.
1981: John W Baynes; Suzanne R Thorpe
Identification of the sites of albumin catabolism in the rat.
Archives of biochemistry and biophysics 1981;206(2):372-9.
1980: R W Thornburg; J F Day; John W Baynes; Suzanne R Thorpe
Carbohydrate-mediated clearance of immune complexes from the circulation. A role for galactose residues in the hepatic uptake of IgG-antigen complexes.
The Journal of biological chemistry 1980;255(14):6820-5.
1980: J F Day; C G Ingebretsen; W R Ingebretsen; John W Baynes; Suzanne R Thorpe
Nonenzymatic glucosylation of serum proteins and hemoglobin: response to changes in blood glucose levels in diabetic rats.
Diabetes 1980;29(7):524-7.
1980: J F Day; R W Thornburg; Suzanne R Thorpe; John W Baynes
Carbohydrate-mediated clearance of antibody . antigen complexes from the circulation. The role of high mannose oligosaccharides in the hepatic uptake of IgM . antigen complexes.
The Journal of biological chemistry 1980;255(6):2360-5.
1980: John W Baynes; J Van Zile; L A Henderson; Suzanne R Thorpe
In vivo sites of uptake of short- and long-lived circulating proteins: clearance of protein in peripheral tissue.
Birth defects original article series 1980;16(1):103-13.
1979: K F McFarland; E W Catalano; J F Day; Suzanne R Thorpe; John W Baynes
Nonenzymatic glucosylation of serum proteins in diabetes mellitus.
Diabetes 1979;28(11):1011-4.
1979: J F Day; R W Thornburg; Suzanne R Thorpe; John W Baynes
Nonenzymatic glucosylation of rat albumin. Studies in vitro and in vivo.
The Journal of biological chemistry 1979;254(19):9394-400.
1979: C E Guthrow; M A Morris; J F Day; Suzanne R Thorpe; John W Baynes
Enhanced nonenzymatic glucosylation of human serum albumin in diabetes mellitus.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(9):4258-61.
1979: J Van Zile; L A Henderson; John W Baynes; Suzanne R Thorpe
[3H]Raffinose, a novel radioactive label for determining organ sites of catabolism of proteins in the circulation.
The Journal of biological chemistry 1979;254(9):3547-53.
1979: J F Day; Suzanne R Thorpe; John W Baynes
Nonenzymatically glucosylated albumin. In vitro preparation and isolation from normal human serum.
The Journal of biological chemistry 1979;254(3):595-7.
1978: T L Brown; L A Henderson; Suzanne R Thorpe; John W Baynes
The effect of alpha-mannose-terminal oligosaccharides on the survival of glycoproteins in the circulation. Rapid uptake and catabolism of bovine pancreatic ribonuclease B by nonparenchymal cells of rat liver.
Archives of biochemistry and biophysics 1978;188(2):418-28.
1978: Suzanne R Thorpe; R J Desnick
Enzyme therapy--IX. Stabilization of human splenic alpha-galactosidase a by zinc ion.
The International journal of biochemistry 1978;9(2):103-5.
1976: R J Desnick; Suzanne R Thorpe; M B Fiddler
Toward enzyme therapy for lysosomal storage diseases.
Physiological reviews 1976;56(1):57-99.
1975: Suzanne R Thorpe; M B Fiddler; R J Desnick
Enzyme therapy. V. In vivo fate of erythrocyte-entrapped beta-glucuronidase in beta-glucuronidase-deficient mice.
Pediatric research 1975;9(12):918-23.
1974: Suzanne R Thorpe; M B Fiddler; R J Desnick
Enzyme therapy IV. A method for determining the in vivo fate of bovine beta-glucuronidase in beta-glucuronidase deficient mice.
Biochemical and biophysical research communications 1974;61(4):1464-70.
1967: Suzanne R Thorpe; C C Sweeley
Chemistry and metabolism of sphingolipids. On the biosynthesis of phytosphingosine by yeast.
Biochemistry 1967;6(3):887-97.