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Carl Thummel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Disorders

Biological Metamorphosis

Living Beings

Physiology

Genes & Molecular Sequences

Insect Genes

Anatomy

Salivary Glands

Concepts & Ideas

Molecular Sequence Data

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Co-Publications
Name
11
Lam, Geanette
8
Karim, Felix
6
Kozlova, Tatiana
6
Beckstead, Robert
5
D'Avino, Pier Paolo
5
Bashirullah, Arash
4
Baker, Keith
4
Jiang, C
4
King-Jones, Kirst
4
Mangelsdorf, David
4
Yin, Viravuth
3
Hogness, David
2
Gilbert, Lawrence
2
Guild, Gregory
2
Baehrecke, Eric

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Publications

TOP 3
Palanker Laura; Tennessen Jason M; Lam Geanette; Thummel Carl S
Drosophila HNF4 regulates lipid mobilization and beta-oxidation.
Kozlova Tatiana; Lam Geanette; Thummel Carl S
Drosophila DHR38 nuclear receptor is required for adult cuticle integrity at eclosion.
Wang Lei; Evans Janelle; Andrews Hillary K; Beckstead Robert B; Thummel Carl S; Bashirullah Arash
A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila.

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All Publications

2009: Palanker Laura; Tennessen Jason M; Lam Geanette; Thummel Carl S
Drosophila HNF4 regulates lipid mobilization and beta-oxidation.
Cell metabolism 2009;9(3):228-39.
2009: Kozlova Tatiana; Lam Geanette; Thummel Carl S
Drosophila DHR38 nuclear receptor is required for adult cuticle integrity at eclosion.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(3):701-7.
2008: Wang Lei; Evans Janelle; Andrews Hillary K; Beckstead Robert B; Thummel Carl S; Bashirullah Arash
A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila.
Genetics 2008;180(1):269-81.
2008: Tennessen Jason M; Thummel Carl S
Developmental timing: let-7 function conserved through evolution.
Current biology : CB 2008;18(16):R707-8.
2008: Ruaud Anne-Françoise; Thummel Carl S
Serotonin and insulin signaling team up to control growth in Drosophila.
Genes & development 2008;22(14):1851-5.
2007: McBrayer Zofeyah; Ono Hajime; Shimell MaryJane; Parvy Jean-Philippe; Beckstead Robert B; Warren James T; Thummel Carl S; Dauphin-Villemant Chantal; Gilbert Lawrence I; O'Connor Michael B
Prothoracicotropic hormone regulates developmental timing and body size in Drosophila.
Developmental cell 2007;13(6):857-71.
2007: Bashirullah Arash; Lam Geanette; Yin Viravuth P; Thummel Carl S
dTrf2 is required for transcriptional and developmental responses to ecdysone during Drosophila metamorphosis.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(11):3173-9.
2007: Baker Keith D; Thummel Carl S
Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila.
Cell metabolism 2007;6(4):257-66.
2007: Yin Viravuth P; Thummel Carl S; Bashirullah Arash
Down-regulation of inhibitor of apoptosis levels provides competence for steroid-triggered cell death.
The Journal of cell biology 2007;178(1):85-92.
2007: Beckstead Robert B; Lam Geanette; Thummel Carl S
Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila.
Insect biochemistry and molecular biology 2007;37(6):570-8.
2007: Thummel Carl S
To die or not to die--a role for Fork head.
The Journal of cell biology 2007;176(6):737-9.
2007: Baker Keith D; Beckstead Robert B; Mangelsdorf David J; Thummel Carl S
Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila.
Genes & development 2007;21(4):450-64.
2006: Palanker Laura; Necakov Aleksandar S; Sampson Heidi M; Ni Ruoyu; Hu Chun; Thummel Carl S; Krause Henry M
Dynamic regulation of Drosophila nuclear receptor activity in vivo.
Development (Cambridge, England) 2006;133(18):3549-62.
2006: King-Jones Kirst; Horner Michael A; Lam Geanette; Thummel Carl S
The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila.
Cell metabolism 2006;4(1):37-48.
2006: Beckstead Robert B; Thummel Carl S
Indicted: worms caught using steroids.
Cell 2006;124(6):1137-40.
2005: King-Jones Kirst; Thummel Carl S
Developmental biology. Less steroids make bigger flies.
Science (New York, N.Y.) 2005;310(5748):630-1.
2005: Thummel Carl S
Powered by gas--a ligand for a fruit fly nuclear receptor.
Cell 2005;122(2):151-3.
2005: King-Jones Kirst; Charles Jean-Philippe; Lam Geanette; Thummel Carl S
The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in Drosophila.
Cell 2005;121(5):773-84.
2005: King-Jones Kirst; Thummel Carl S
Nuclear receptors--a perspective from Drosophila.
Nature reviews. Genetics 2005;6(4):311-23.
2005: Yin Viravuth P; Thummel Carl S
Mechanisms of steroid-triggered programmed cell death in Drosophila.
Seminars in cell & developmental biology 2005;16(2):237-43.
2005: Beckstead Robert B; Lam Geanette; Thummel Carl S
The genomic response to 20-hydroxyecdysone at the onset of Drosophila metamorphosis.
Genome biology 2005;6(12):R99.
2004: Yin Viravuth P; Thummel Carl S
A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(21):8022-7.
2004: Gates Julie; Lam Geanette; Ortiz José A; Losson Régine; Thummel Carl S
rigor mortis encodes a novel nuclear receptor interacting protein required for ecdysone signaling during Drosophila larval development.
Development (Cambridge, England) 2004;131(1):25-36.
2003: Astle John; Kozlova Tatiana; Thummel Carl S
Essential roles for the Dhr78 orphan nuclear receptor during molting of the Drosophila tracheal system.
Insect biochemistry and molecular biology 2003;33(12):1201-9.
2003: Ward Robert E; Evans Janelle; Thummel Carl S
Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis.
Genetics 2003;165(3):1397-415.
2003: Sullivan April A; Thummel Carl S
Temporal profiles of nuclear receptor gene expression reveal coordinate transcriptional responses during Drosophila development.
Molecular endocrinology (Baltimore, Md.) 2003;17(11):2125-37.
2003: Kozlova Tatiana; Thummel Carl S
Essential roles for ecdysone signaling during Drosophila mid-embryonic development.
Science (New York, N.Y.) 2003;301(5641):1911-4.
2003: Bashirullah Arash; Pasquinelli Amy E; Kiger Amy A; Perrimon Norbert; Ruvkun Gary; Thummel Carl S
Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis.
Developmental biology 2003;259(1):1-8.
2003: Baker Keith D; Shewchuk Lisa M; Kozlova Tatiana; Makishima Makoto; Hassell Annie; Wisely Bruce; Caravella Justin A; Lambert Millard H; Reinking Jeffrey L; Krause Henry; Thummel Carl S; Willson Timothy M; Mangelsdorf David J
The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway.
Cell 2003;113(6):731-42.
2003: Ward Robert E; Reid Pamela; Bashirullah Arash; D'Avino Pier Paolo; Thummel Carl S
GFP in living animals reveals dynamic developmental responses to ecdysone during Drosophila metamorphosis.
Developmental biology 2003;256(2):389-402.
2003: Kozlova Tatiana; Thummel Carl S
Methods to characterize Drosophila nuclear receptor activation and function in vivo.
Methods in enzymology 2003;364():475-90.
2002: Thummel Carl S; Chory Joanne
Steroid signaling in plants and insects--common themes, different pathways.
Genes & development 2002;16(24):3113-29.
2002: Bialecki Michael; Shilton Alycia; Fichtenberg Caroline; Segraves William A; Thummel Carl S
Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila.
Developmental cell 2002;3(2):209-20.
2002: Lehmann M; Jiang C; Ip Y T; Thummel C S
AP-1, but not NF-kappa B, is required for efficient steroid-triggered cell death in Drosophila.
Cell death and differentiation 2002;9(5):581-90.
2002: Kozlova Tatiana; Thummel Carl S
Spatial patterns of ecdysteroid receptor activation during the onset of Drosophila metamorphosis.
Development (Cambridge, England) 2002;129(7):1739-50.
2002: Thummel C S
Ecdysone-regulated puff genes 2000.
Insect biochemistry and molecular biology 2002;32(2):113-20.
2001: Thummel C S
Molecular mechanisms of developmental timing in C. elegans and Drosophila.
Developmental cell 2001;1(4):453-65.
2001: Thummel C S
Steroid-triggered death by autophagy.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(8):677-82.
2000: Gates J; Thummel C S
An enhancer trap screen for ecdysone-inducible genes required for Drosophila adult leg morphogenesis.
Genetics 2000;156(4):1765-76.
2000: Baker K D; Warren J T; Thummel C S; Gilbert L I; Mangelsdorf D J
Transcriptional activation of the Drosophila ecdysone receptor by insect and plant ecdysteroids.
Insect biochemistry and molecular biology 2000;30(11):1037-43.
2000: Vaskova M; Bentley A M; Marshall S; Reid P; Thummel C S; Andres A J
Genetic analysis of the Drosophila 63F early puff. Characterization of mutations in E63-1 and maggie, a putative Tom22.
Genetics 2000;156(1):229-44.
2000: Lam G; Thummel C S
Inducible expression of double-stranded RNA directs specific genetic interference in Drosophila.
Current biology : CB 2000;10(16):957-63.
2000: Lee C Y; Wendel D P; Reid P; Lam G; Thummel C S; Baehrecke E H
E93 directs steroid-triggered programmed cell death in Drosophila.
Molecular cell 2000;6(2):433-43.
2000: D'Avino P P; Thummel C S
The ecdysone regulatory pathway controls wing morphogenesis and integrin expression during Drosophila metamorphosis.
Developmental biology 2000;220(2):211-24.
2000: Jiang C; Lamblin A F; Steller H; Thummel C S
A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis.
Molecular cell 2000;5(3):445-55.
1999: Lam G; Hall B L; Bender M; Thummel C S
DHR3 is required for the prepupal-pupal transition and differentiation of adult structures during Drosophila metamorphosis.
Developmental biology 1999;212(1):204-16.
1999: Broadus J; McCabe J R; Endrizzi B; Thummel C S; Woodard C T
The Drosophila beta FTZ-F1 orphan nuclear receptor provides competence for stage-specific responses to the steroid hormone ecdysone.
Molecular cell 1999;3(2):143-9.
1999: D'Avino P P; Thummel C S
Ectopic expression systems in Drosophila.
Methods in enzymology 1999;306():129-42.
1998: Hall B L; Thummel C S
The RXR homolog ultraspiracle is an essential component of the Drosophila ecdysone receptor.
Development (Cambridge, England) 1998;125(23):4709-17.
1998: Fisk G J; Thummel C S
The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosis.
Cell 1998;93(4):543-55.
1998: D'Avino P P; Thummel C S
crooked legs encodes a family of zinc finger proteins required for leg morphogenesis and ecdysone-regulated gene expression during Drosophila metamorphosis.
Development (Cambridge, England) 1998;125(9):1733-45.
1997: Jiang C; Baehrecke E H; Thummel C S
Steroid regulated programmed cell death during Drosophila metamorphosis.
Development (Cambridge, England) 1997;124(22):4673-83.
1997: Thummel C S
Dueling orphans--interacting nuclear receptors coordinate Drosophila metamorphosis.
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(8):669-72.
1997: Lam G T; Jiang C; Thummel C S
Coordination of larval and prepupal gene expression by the DHR3 orphan receptor during Drosophila metamorphosis.
Development (Cambridge, England) 1997;124(9):1757-69.
1997: Fletcher J C; D'Avino P P; Thummel C S
A steroid-triggered switch in E74 transcription factor isoforms regulates the timing of secondary-response gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4582-6.
1996: Thummel C S
Files on steroids--Drosophila metamorphosis and the mechanisms of steroid hormone action.
Trends in genetics : TIG 1996;12(8):306-10.
1996: Wright L G; Chen T; Thummel C S; Guild G M
Molecular characterization of the 71E late puff in Drosophila melanogaster reveals a family of novel genes.
Journal of molecular biology 1996;255(3):387-400.
1995: Urness L D; Thummel C S
Molecular analysis of a steroid-induced regulatory hierarchy: the Drosophila E74A protein directly regulates L71-6 transcription.
The EMBO journal 1995;14(24):6239-46.
1995: Thummel C S
From embryogenesis to metamorphosis: the regulation and function of Drosophila nuclear receptor superfamily members.
Cell 1995;83(6):871-7.
1995: Mangelsdorf D J; Thummel C; Beato M; Herrlich P; Schütz G; Umesono K; Blumberg B; Kastner P; Mark M; Chambon P; Evans R M
The nuclear receptor superfamily: the second decade.
Cell 1995;83(6):835-9.
1995: Fletcher J C; Thummel C S
The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.
Genetics 1995;141(3):1025-35.
1995: Fisk G J; Thummel C S
Isolation, regulation, and DNA-binding properties of three Drosophila nuclear hormone receptor superfamily members.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10604-8.
1995: Baehrecke E H; Thummel C S
The Drosophila E93 gene from the 93F early puff displays stage- and tissue-specific regulation by 20-hydroxyecdysone.
Developmental biology 1995;171(1):85-97.
1995: Andres A J; Thummel C S
The Drosophila 63F early puff contains E63-1, an ecdysone-inducible gene that encodes a novel Ca(2+)-binding protein.
Development (Cambridge, England) 1995;121(8):2667-79.
1995: Fletcher J C; Burtis K C; Hogness D S; Thummel C S
The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone.
Development (Cambridge, England) 1995;121(5):1455-65.
1995: Fletcher J C; Thummel C S
The Drosophila E74 gene is required for the proper stage- and tissue-specific transcription of ecdysone-regulated genes at the onset of metamorphosis.
Development (Cambridge, England) 1995;121(5):1411-21.
1995: Horner M A; Chen T; Thummel C S
Ecdysteroid regulation and DNA binding properties of Drosophila nuclear hormone receptor superfamily members.
Developmental biology 1995;168(2):490-502.
1994: Woodard C T; Baehrecke E H; Thummel C S
A molecular mechanism for the stage specificity of the Drosophila prepupal genetic response to ecdysone.
Cell 1994;79(4):607-15.
1994: Andres A J; Thummel C S
Methods for quantitative analysis of transcription in larvae and prepupae.
Methods in cell biology 1994;44():565-73.
1993: Andres A J; Fletcher J C; Karim F D; Thummel C S
Molecular analysis of the initiation of insect metamorphosis: a comparative study of Drosophila ecdysteroid-regulated transcription.
Developmental biology 1993;160(2):388-404.
1993: Hurban P; Thummel C S
Isolation and characterization of fifteen ecdysone-inducible Drosophila genes reveal unexpected complexities in ecdysone regulation.
Molecular and cellular biology 1993;13(11):7101-11.
1993: Boyd L; Thummel C S
Selection of CUG and AUG initiator codons for Drosophila E74A translation depends on downstream sequences.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):9164-7.
1993: Stone B L; Thummel C S
The Drosophila 78C early late puff contains E78, an ecdysone-inducible gene that encodes a novel member of the nuclear hormone receptor superfamily.
Cell 1993;75(2):307-20.
1993: Karim F D; Guild G M; Thummel C S
The Drosophila Broad-Complex plays a key role in controlling ecdysone-regulated gene expression at the onset of metamorphosis.
Development (Cambridge, England) 1993;118(3):977-88.
1993: Lavorgna G; Karim F D; Thummel C S; Wu C
Potential role for a FTZ-F1 steroid receptor superfamily member in the control of Drosophila metamorphosis.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):3004-8.
1992: Karim F D; Thummel C S
Temporal coordination of regulatory gene expression by the steroid hormone ecdysone.
The EMBO journal 1992;11(11):4083-93.
1992: Chen T; Bunting M; Karim F D; Thummel C S
Isolation and characterization of five Drosophila genes that encode an ets-related DNA binding domain.
Developmental biology 1992;151(1):176-91.
1992: Andres A J; Thummel C S
Hormones, puffs and flies: the molecular control of metamorphosis by ecdysone.
Trends in genetics : TIG 1992;8(4):132-8.
1992: Thummel C S
Mechanisms of transcriptional timing in Drosophila.
Science (New York, N.Y.) 1992;255(5040):39-40.
1991: Boyd L; O'Toole E; Thummel C S
Patterns of E74A RNA and protein expression at the onset of metamorphosis in Drosophila.
Development (Cambridge, England) 1991;112(4):981-95.
1991: Karim F D; Thummel C S
Ecdysone coordinates the timing and amounts of E74A and E74B transcription in Drosophila.
Genes & development 1991;5(6):1067-79.
1990: Thummel C S
Puffs and gene regulation--molecular insights into the Drosophila ecdysone regulatory hierarchy.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(12):561-8.
1990: LeMaire M F; Thummel C S
Splicing precedes polyadenylation during Drosophila E74A transcription.
Molecular and cellular biology 1990;10(11):6059-63.
1990: Urness L D; Thummel C S
Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein.
Cell 1990;63(1):47-61.
1990: Karim F D; Urness L D; Thummel C S; Klemsz M J; McKercher S R; Celada A; Van Beveren C; Maki R A; Gunther C V; Nye J A
The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence.
Genes & development 1990;4(9):1451-3.
1990: Burtis K C; Thummel C S; Jones C W; Karim F D; Hogness D S
The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins.
Cell 1990;61(1):85-99.
1990: Thummel C S; Burtis K C; Hogness D S
Spatial and temporal patterns of E74 transcription during Drosophila development.
Cell 1990;61(1):101-11.
1989: Thummel C S
The Drosophila E74 promoter contains essential sequences downstream from the start site of transcription.
Genes & development 1989;3(6):782-92.
1988: Thummel C S; Boulet A M; Lipshitz H D
Vectors for Drosophila P-element-mediated transformation and tissue culture transfection.
Gene 1988;74(2):445-56.

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