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Ronald Thurman

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Peter Schemmer; Michael D Wheeler; Li Xiangli; Zhi Zhong; José Boyer; Blair U Bradford; Lars O Conzelmann; Dow Forman; Uwe Galli; Ronald G Thurman
Glycine reduces platelet aggregation.
Erwin Gäbele; Matthias Froh; Gavin E Arteel; Takehiko Uesugi; Claus Hellerbrand; Jürgen Schölmerich; David A Brenner; Ronald G Thurman; Richard A Rippe
TNFalpha is required for cholestasis-induced liver fibrosis in the mouse.
Matthias Froh; Lars Conzelmann; Peter Walbrun; Susanne Netter; Reiner Wiest; Michael D Wheeler; Mark Lehnert; Takehiko Uesugi; Jurgen Scholmerich; Ronald G Thurman
Heme oxygenase-1 overexpression increases liver injury after bile duct ligation in rats.

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All Publications

2013: Peter Schemmer; Michael D Wheeler; Li Xiangli; Zhi Zhong; José Boyer; Blair U Bradford; Lars O Conzelmann; Dow Forman; Uwe Galli; Ronald G Thurman
Glycine reduces platelet aggregation.
Amino acids 2013;44(3):925-31.
2009: Erwin Gäbele; Matthias Froh; Gavin E Arteel; Takehiko Uesugi; Claus Hellerbrand; Jürgen Schölmerich; David A Brenner; Ronald G Thurman; Richard A Rippe
TNFalpha is required for cholestasis-induced liver fibrosis in the mouse.
Biochemical and biophysical research communications 2009;378(3):348-53.
2007: Matthias Froh; Lars Conzelmann; Peter Walbrun; Susanne Netter; Reiner Wiest; Michael D Wheeler; Mark Lehnert; Takehiko Uesugi; Jurgen Scholmerich; Ronald G Thurman
Heme oxygenase-1 overexpression increases liver injury after bile duct ligation in rats.
World journal of gastroenterology : WJG 2007;13(25):3478-86.
2006: Zhi Zhong; Henry D Connor; Xiangli Li; Ronald P Mason; Donald Forman; John J Lemasters; Ronald G Thurman
Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols.
The Journal of pharmacy and pharmacology 2006;58(11):1533-43.
2005: Zhi Zhong; Henry D Connor; Matthias Froh; Hartwig Bunzendahl; Henrik Lind; Mark Lehnert; Ronald P Mason; Ronald G Thurman; John J Lemasters
Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols.
Gastroenterology 2005;129(2):652-64.
2004: Zhi Zhong; Henry D Connor; Matthias Froh; Henrik Lind; Hartwig Bunzendahl; Ronald P Mason; Ronald G Thurman; John J Lemasters
Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats.
Free radical biology & medicine 2004;36(10):1248-58.
2004: Xiangli Li; Blair U Bradford; Frederick Dalldorf; Sanna Goyert; Stephen A Stimpson; Ronald G Thurman; Sergei S Makarov
CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan-polysaccharide complexes of Gram-positive bacterial cell walls.
Arthritis research & therapy 2004;6(3):R273-81.
2003: Zhi Zhong; Matthias Froh; Mark Lehnert; Robert Schoonhoven; Liu Yang; Henrik Lind; John J Lemasters; Ronald G Thurman
Polyphenols from Camellia sinenesis attenuate experimental cholestasis-induced liver fibrosis in rats.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(5):G1004-13.
2003: Thorsten G Lehmann; Michael D Wheeler; Matthias Froh; Robert F Schwabe; Hartwig Bunzendahl; R Jude Samulski; John J Lemasters; David A Brenner; Ronald G Thurman
Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat.
Transplantation 2003;76(1):28-37.
2003: Mark Lehnert; Gavin E Arteel; Olivia M Smutney; Lars O Conzelmann; Zhi Zhong; Ronald G Thurman; John J Lemasters
Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide.
Shock (Augusta, Ga.) 2003;19(4):345-51.
2003: Michael D Wheeler; Ronald G Thurman
Up-regulation of CD14 in liver caused by acute ethanol involves oxidant-dependent AP-1 pathway.
The Journal of biological chemistry 2003;278(10):8435-41.
2003: Matthias Froh; Akira Konno; Ronald G Thurman
Isolation of liver Kupffer cells.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2003;Chapter 14():Unit14.4.
2003: Michael D Wheeler; Olivia M Smutney; Jennifer F Check; Ivan Rusyn; R Schulte-Hermann; Ronald G Thurman
Impaired Ras membrane association and activation in PPARalpha knockout mice after partial hepatectomy.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(2):G302-12.
2003: Matthias Froh; Michael D Wheeler; Olivia M Smutney; Zhi Zhong; Blair U Bradford; Ronald G Thurman
New method of delivering gene-altered Kupffer cells to rat liver: studies in an ischemia-reperfusion model.
Gastroenterology 2003;124(1):172-83.
2002: Wei Qu; Kenichi Ikejima; Zhi Zhong; Michael P Waalkes; Ronald G Thurman
Glycine blocks the increase in intracellular free Ca2+ due to vasoactive mediators in hepatic parenchymal cells.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(6):G1249-56.
2002: Keizo Sato; Maria B Kadiiska; Andrew J Ghio; Jean Corbett; Yang C Fann; Steven M Holland; Ronald G Thurman; Ronald P Mason
In vivo lipid-derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(13):1713-20.
2002: Stephen E McKim; Akira Konno; Erwin Gäbele; Takehiko Uesugi; Matthias Froh; Helmut Sies; Ronald G Thurman; Gavin E Arteel
Cocoa extract protects against early alcohol-induced liver injury in the rat.
Archives of biochemistry and biophysics 2002;406(1):40-6.
2002: Zhi Zhong; Matthias Froh; Henry D Connor; Xiangli Li; Lars O Conzelmann; Ronald P Mason; John J Lemasters; Ronald G Thurman
Prevention of hepatic ischemia-reperfusion injury by green tea extract.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(4):G957-64.
2002: Matthias Froh; Ronald G Thurman; Michael D Wheeler
Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(4):G856-63.
2002: Lars O Conzelmann; Peter Schemmer; Zhi Zhong; Olivia M Smutney; Hartwig Bunzendahl; Ronald G Thurman
Orthotopic liver transplantation in knockout mice: is TNFalpha involved in early graft injury and regeneration?
Transplantation proceedings 2002;34(6):2299-300.
2002: Brian J Dewar; Blair U Bradford; Ronald G Thurman
Nicotine increases hepatic oxygen uptake in the isolated perfused rat liver by inhibiting glycolysis.
The Journal of pharmacology and experimental therapeutics 2002;301(3):930-7.
2002: Takehiko Uesugi; Matthias Froh; Gavin E Arteel; Blair U Bradford; Michael D Wheeler; Erwin Gäbele; Fuyumi Isayama; Ronald G Thurman
Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(6):2963-9.
2002: Gavin E Arteel; Takehiko Uesugi; Leslie N Bevan; Erwin Gäbele; Michael D Wheeler; Stephen E McKim; Ronald G Thurman
Green tea extract protects against early alcohol-induced liver injury in rats.
Biological chemistry 2002;383(3-4):663-70.
2002: Ming Yin; Zhi Zhong; Henry D Connor; Hartwig Bunzendahl; William F Finn; Ivan Rusyn; Xiangli Li; James Raleigh; Ronald P Mason; Ronald G Thurman
Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo.
American journal of physiology. Renal physiology 2002;282(3):F417-23.
2002: Zhi Zhong; Matthias Froh; Michael D Wheeler; Olivia M Smutney; Thorsten G Lehmann; Ronald G Thurman
Viral gene delivery of superoxide dismutase attenuates experimental cholestasis-induced liver fibrosis in the rat.
Gene therapy 2002;9(3):183-91.
2002: Christine A Charrueau; Alain Carayon; Ronald G Thurman
Long-term cold liver storage induces endothelin-1 release and a time-dependent increase in portal pressure at reperfusion in the rat.
Journal of gastroenterology 2002;37(9):717-25.
2001: Michael D Wheeler; Hiroshi Kono; M Yin; M Nakagami; Takehiko Uesugi; Gavin E Arteel; Erwin Gäbele; Ivan Rusyn; S Yamashina; Matthias Froh; Y Adachi; Yuji Iimuro; Blair U Bradford; Olivia M Smutney; Henry D Connor; Ronald P Mason; Sanna Goyert; J M Peters; F J Gonzalez; R Jude Samulski; Ronald G Thurman
The role of Kupffer cell oxidant production in early ethanol-induced liver disease.
Free radical biology & medicine 2001;31(12):1544-9.
2001: Michael D Wheeler; M Katuna; Olivia M Smutney; Matthias Froh; Anna Dikalova; Ronald P Mason; R Jude Samulski; Ronald G Thurman
Comparison of the effect of adenoviral delivery of three superoxide dismutase genes against hepatic ischemia-reperfusion injury.
Human gene therapy 2001;12(18):2167-77.
2001: Takehiko Uesugi; Matthias Froh; Gavin E Arteel; Blair U Bradford; Erwin Gäbele; Michael D Wheeler; Ronald G Thurman
Delivery of IkappaB superrepressor gene with adenovirus reduces early alcohol-induced liver injury in rats.
Hepatology (Baltimore, Md.) 2001;34(6):1149-57.
2001: M Yin; Michael D Wheeler; Henry D Connor; Zhi Zhong; Hartwig Bunzendahl; Anna Dikalova; R Jude Samulski; Robert Schoonhoven; R P Mason; James A Swenberg; Ronald G Thurman
Cu/Zn-superoxide dismutase gene attenuates ischemia-reperfusion injury in the rat kidney.
Journal of the American Society of Nephrology : JASN 2001;12(12):2691-700.
2001: Zhi Zhong; X Li; S Yamashina; M von Frankenberg; N Enomoto; Kenichi Ikejima; M Kolinsky; James Raleigh; Ronald G Thurman
Cyclosporin A causes a hypermetabolic state and hypoxia in the liver: prevention by dietary glycine.
The Journal of pharmacology and experimental therapeutics 2001;299(3):858-65.
2001: M Yin; Erwin Gäbele; Michael D Wheeler; Henry D Connor; Blair U Bradford; Anna Dikalova; Ivan Rusyn; R Mason; Ronald G Thurman
Alcohol-induced free radicals in mice: direct toxicants or signaling molecules?
Hepatology (Baltimore, Md.) 2001;34(5):935-42.
2001: Michael D Wheeler; M Nakagami; Blair U Bradford; Takehiko Uesugi; Ronald P Mason; Henry D Connor; Anna Dikalova; Maria B Kadiiska; Ronald G Thurman
Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat.
The Journal of biological chemistry 2001;276(39):36664-72.
2001: N Enomoto; Peter Schemmer; Kenichi Ikejima; Yoshiyuki Takei; Nobuhiro Sato; David A Brenner; Ronald G Thurman
Long-term alcohol exposure changes sensitivity of rat Kupffer cells to lipopolysaccharide.
Alcoholism, clinical and experimental research 2001;25(9):1360-7.
2001: Xiangli Li; Blair U Bradford; Michael D Wheeler; Stephen A Stimpson; Heather M Pink; Thomas A Brodie; J H Schwab; Ronald G Thurman
Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel.
Infection and immunity 2001;69(9):5883-91.
2001: Takehiko Uesugi; Matthias Froh; Gavin E Arteel; Blair U Bradford; Ronald G Thurman
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice.
Hepatology (Baltimore, Md.) 2001;34(1):101-8.
2001: CA Rivera; Blair U Bradford; K J Hunt; Y Adachi; Laura W Schrum; Dennis R Koop; ER Burchardt; Richard A Rippe; Ronald G Thurman
Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(1):G200-7.
2001: Hiroshi Kono; Takehiko Uesugi; Matthias Froh; Ivan Rusyn; Blair U Bradford; Ronald G Thurman
ICAM-1 is involved in the mechanism of alcohol-induced liver injury: studies with knockout mice.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(6):G1289-95.
2001: Hiroshi Kono; M Nakagami; Ivan Rusyn; Henry D Connor; Branko Stefanovic; David A Brenner; Ronald P Mason; Gavin E Arteel; Ronald G Thurman
Development of an animal model of chronic alcohol-induced pancreatitis in the rat.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(6):G1178-86.
2001: Peter Schemmer; N Enomoto; Blair U Bradford; Hartwig Bunzendahl; James Raleigh; John J Lemasters; Ronald G Thurman
Activated Kupffer cells cause a hypermetabolic state after gentle in situ manipulation of liver in rats.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(6):G1076-82.
2001: Hiroshi Kono; Ivan Rusyn; Takehiko Uesugi; S Yamashina; Henry D Connor; Anna Dikalova; Ronald P Mason; Ronald G Thurman
Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(5):G1005-12.
2001: Peter Schemmer; N Enomoto; Blair U Bradford; Hartwig Bunzendahl; James Raleigh; Ronald G Thurman
Autonomic nervous system and gut-derived endotoxin: involvement in activation of Kupffer cells after in situ organ manipulation.
World journal of surgery 2001;25(4):399-406.
2001: Michael D Wheeler; S Yamashina; Matthias Froh; Ivan Rusyn; Ronald G Thurman
Adenoviral gene delivery can inactivate Kupffer cells: role of oxidants in NF-kappaB activation and cytokine production.
Journal of leukocyte biology 2001;69(4):622-30.
2001: M Arai; Ronald G Thurman; John J Lemasters
Ischemic preconditioning of rat livers against cold storage-reperfusion injury: role of nonparenchymal cells and the phenomenon of heterologous preconditioning.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2001;7(4):292-9.
2001: Michael D Wheeler; Hiroshi Kono; M Yin; Ivan Rusyn; Matthias Froh; Henry D Connor; Ronald P Mason; R Jude Samulski; Ronald G Thurman
Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats.
Gastroenterology 2001;120(5):1241-50.
2001: Ivan Rusyn; Maria B Kadiiska; Anna Dikalova; Hiroshi Kono; M Yin; K Tsuchiya; Ronald P Mason; J M Peters; F J Gonzalez; BH Segal; SM Holland; Ronald G Thurman
Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells.
Molecular pharmacology 2001;59(4):744-50.
2001: M Yin; Blair U Bradford; Michael D Wheeler; Takehiko Uesugi; Matthias Froh; Sanna Goyert; Ronald G Thurman
Reduced early alcohol-induced liver injury in CD14-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4737-42.
2001: Hiroshi Kono; Gavin E Arteel; Ivan Rusyn; Helmut Sies; Ronald G Thurman
Ebselen prevents early alcohol-induced liver injury in rats.
Free radical biology & medicine 2001;30(4):403-11.
2001: S Yamashina; A Konno; Michael D Wheeler; Ivan Rusyn; Elena V Rusyn; Adrienne D Cox; Ronald G Thurman
Endothelial cells contain a glycine-gated chloride channel.
Nutrition and cancer 2001;40(2):197-204.
2000: Ivan Rusyn; Mikhail F Denissenko; Victoria A Wong; Byron E Butterworth; Michael L Cunningham; Patricia B Upton; Ronald G Thurman; James A Swenberg
Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency.
Carcinogenesis 2000;21(12):2141-5.
2000: Thorsten G Lehmann; Michael D Wheeler; Robert F Schwabe; Henry D Connor; Robert Schoonhoven; Hartwig Bunzendahl; David A Brenner; R Jude Samulski; Zhi Zhong; Ronald G Thurman
Gene delivery of Cu/Zn-superoxide dismutase improves graft function after transplantation of fatty livers in the rat.
Hepatology (Baltimore, Md.) 2000;32(6):1255-64.
2000: S Yamashina; Michael D Wheeler; Ivan Rusyn; Kenichi Ikejima; Nobuhiro Sato; Ronald G Thurman
Tolerance and sensitization to endotoxin in Kupffer cells caused by acute ethanol involve interleukin-1 receptor-associated kinase.
Biochemical and biophysical research communications 2000;277(3):686-90.
2000: Ronald G Thurman
Sex-related liver injury due to alcohol involves activation of Kupffer cells by endotoxin.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2000;14 Suppl D():129D-135D.
2000: Michael D Wheeler; Hiroshi Kono; Ivan Rusyn; Gavin E Arteel; Douglass Mccarty; R Jude Samulski; Ronald G Thurman
Chronic ethanol increases adeno-associated viral transgene expression in rat liver via oxidant and NFkappaB-dependent mechanisms.
Hepatology (Baltimore, Md.) 2000;32(5):1050-9.
2000: Hiroshi Kono; Ivan Rusyn; M Yin; Erwin Gäbele; S Yamashina; Anna Dikalova; Maria B Kadiiska; Henry D Connor; Ronald P Mason; BH Segal; Blair U Bradford; SM Holland; Ronald G Thurman
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.
The Journal of clinical investigation 2000;106(7):867-72.
2000: Ivan Rusyn; S Yamashina; BH Segal; Robert Schoonhoven; SM Holland; Russell C Cattley; James A Swenberg; Ronald G Thurman
Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.
Cancer research 2000;60(17):4798-803.
2000: Michael D Wheeler; ML Rose; S Yamashima; N Enomoto; VITOR SEABRA; J Madren; Ronald G Thurman
Dietary glycine blunts lung inflammatory cell influx following acute endotoxin.
American journal of physiology. Lung cellular and molecular physiology 2000;279(2):L390-8.
2000: N Enomoto; Kenichi Ikejima; S Yamashina; A Enomoto; T Nishiura; T Nishimura; David A Brenner; Peter Schemmer; Blair U Bradford; CA Rivera; Zhi Zhong; Ronald G Thurman
Kupffer cell-derived prostaglandin E(2) is involved in alcohol-induced fat accumulation in rat liver.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(1):G100-6.
2000: N Enomoto; Kenichi Ikejima; Tsuneo Kitamura; H Oide; Yoshiyuki Takei; Nobuhiro Sato; Ronald G Thurman
Alcohol enhances lipopolysaccharide-induced increases in nitric oxide production by Kupffer cells via mechanisms dependent on endotoxin.
Alcoholism, clinical and experimental research 2000;24(4 Suppl):55S-58S.
2000: Hiroshi Kono; Michael D Wheeler; Ivan Rusyn; M Lin; VITOR SEABRA; CA Rivera; Blair U Bradford; Donald Forman; Ronald G Thurman
Gender differences in early alcohol-induced liver injury: role of CD14, NF-kappaB, and TNF-alpha.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(4):G652-61.
2000: Hiroshi Kono; Ivan Rusyn; Blair U Bradford; Henry D Connor; Ronald P Mason; Ronald G Thurman
Allopurinol prevents early alcohol-induced liver injury in rats.
The Journal of pharmacology and experimental therapeutics 2000;293(1):296-303.
2000: Thorsten G Lehmann; Michael D Wheeler; Robert Schoonhoven; Hartwig Bunzendahl; R Jude Samulski; Ronald G Thurman
Delivery of Cu/Zn-superoxide dismutase genes with a viral vector minimizes liver injury and improves survival after liver transplantation in the rat.
Transplantation 2000;69(6):1051-7.
2000: ML Rose; Ivan Rusyn; HK Bojes; J Belyea; Russell C Cattley; Ronald G Thurman
Role of Kupffer cells and oxidants in signaling peroxisome proliferator-induced hepatocyte proliferation.
Mutation research 2000;448(2):179-92.
2000: M Yin; Ivan Rusyn; Robert Schoonhoven; Lee M Graves; Elena V Rusyn; X Li; F Li; Adrienne D Cox; T W Harding; Hartwig Bunzendahl; James A Swenberg; Ronald G Thurman
Inhibition of chronic rejection of aortic allografts by dietary glycine.
Transplantation 2000;69(5):773-80.
2000: N Enomoto; Kenichi Ikejima; Blair U Bradford; CA Rivera; Hiroshi Kono; M Goto; S Yamashina; Peter Schemmer; Tsuneo Kitamura; H Oide; Yoshiyuki Takei; Miyoko Hirose; H Shimizu; Akihisa Miyazaki; David A Brenner; Nobuhiro Sato; Ronald G Thurman
Role of Kupffer cells and gut-derived endotoxins in alcoholic liver injury.
Journal of gastroenterology and hepatology 2000;15 Suppl():D20-5.
2000: Hiroshi Kono; N Enomoto; Henry D Connor; Michael D Wheeler; Blair U Bradford; CA Rivera; Maria B Kadiiska; Ronald P Mason; Ronald G Thurman
Medium-chain triglycerides inhibit free radical formation and TNF-alpha production in rats given enteral ethanol.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(3):G467-76.
2000: Michael D Wheeler; Robert Stachlewitz; S Yamashina; Kenichi Ikejima; A Leslie Morrow; Ronald G Thurman
Glycine-gated chloride channels in neutrophils attenuate calcium influx and superoxide production.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(3):476-84.
2000: Peter Schemmer; B U Bradford; Hartwig Bunzendahl; John J Lemasters; Ronald G Thurman
Gentle in situ liver manipulation during organ harvest increases oxygen consumption in liver.
Transplantation proceedings 2000;32(1):112.
2000: Yuji Iimuro; Blair U Bradford; S Yamashina; Ivan Rusyn; M Nakagami; N Enomoto; Hiroshi Kono; W Frey; Donald Forman; David A Brenner; Ronald G Thurman
The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat.
Hepatology (Baltimore, Md.) 2000;31(2):391-8.
2000: Ivan Rusyn; ML Rose; HK Bojes; Ronald G Thurman
Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators.
Antioxidants & redox signaling 2000;2(3):607-21.
2000: Hiroshi Kono; Blair U Bradford; Ivan Rusyn; H Fujii; Y Matsumoto; M Yin; Ronald G Thurman
Development of an intragastric enteral model in the mouse: studies of alcohol-induced liver disease using knockout technology.
Journal of hepato-biliary-pancreatic surgery 2000;7(4):395-400.
2000: Peter Schemmer; Hartwig Bunzendahl; E Klar; Ronald G Thurman
Reperfusion injury is dramatically increased by gentle liver manipulation during harvest.
Transplant international : official journal of the European Society for Organ Transplantation 2000;13 Suppl 1():S525-7.
2000: M Yin; Kenichi Ikejima; Michael D Wheeler; Blair U Bradford; VITOR SEABRA; Donald Forman; Nobuhiro Sato; Ronald G Thurman
Estrogen is involved in early alcohol-induced liver injury in a rat enteral feeding model.
Hepatology (Baltimore, Md.) 2000;31(1):117-23.
2000: Robert Stachlewitz; X Li; S Smith; Hartwig Bunzendahl; Lee M Graves; Ronald G Thurman
Glycine inhibits growth of T lymphocytes by an IL-2-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):176-82.
1999: Hiroshi Kono; Blair U Bradford; M Yin; Kathleen K Sulik; Dennis R Koop; J M Peters; F J Gonzalez; T McDonald; Anna Dikalova; Maria B Kadiiska; Ronald P Mason; Ronald G Thurman
CYP2E1 is not involved in early alcohol-induced liver injury.
The American journal of physiology 1999;277(6 Pt 1):G1259-67.
1999: N Enomoto; S Yamashina; M Goto; Peter Schemmer; Ronald G Thurman
Desensitization to LPS after ethanol involves the effect of endotoxin on voltage-dependent calcium channels.
The American journal of physiology 1999;277(6 Pt 1):G1251-8.
1999: Michael D Wheeler; K Ikejema; N Enomoto; R F Stacklewitz; VITOR SEABRA; Zhi Zhong; M Yin; Peter Schemmer; ML Rose; Ivan Rusyn; Blair U Bradford; Ronald G Thurman
Glycine: a new anti-inflammatory immunonutrient.
Cellular and molecular life sciences : CMLS 1999;56(9-10):843-56.
1999: Michael D Wheeler; Ronald G Thurman
Production of superoxide and TNF-alpha from alveolar macrophages is blunted by glycine.
The American journal of physiology 1999;277(5 Pt 1):L952-9.
1999: W Qu; Lee M Graves; Ronald G Thurman
PGE(2) stimulates O(2) uptake in hepatic parenchymal cells: involvement of the cAMP-dependent protein kinase.
The American journal of physiology 1999;277(5 Pt 1):G1048-54.
1999: Ivan Rusyn; Cynthia A Bradham; L Cohn; Robert Schoonhoven; James A Swenberg; David A Brenner; Ronald G Thurman
Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms.
Carcinogenesis 1999;20(11):2095-100.
1999: ML Rose; Russell C Cattley; Corrie Dunn; V Wong; X Li; Ronald G Thurman
Dietary glycine prevents the development of liver tumors caused by the peroxisome proliferator WY-14,643.
Carcinogenesis 1999;20(11):2075-81.
1999: M Yin; Michael D Wheeler; Hiroshi Kono; Blair U Bradford; RM Gallucci; Michael I Luster; Ronald G Thurman
Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice.
Gastroenterology 1999;117(4):942-52.
1999: N Enomoto; S Yamashina; Peter Schemmer; CA Rivera; Blair U Bradford; A Enomoto; David A Brenner; Ronald G Thurman
Estriol sensitizes rat Kupffer cells via gut-derived endotoxin.
The American journal of physiology 1999;277(3 Pt 1):G671-7.
1999: Zhi Zhong; Henry D Connor; M Yin; Nicholas Moss; Ronald P Mason; Hartwig Bunzendahl; Donald Forman; Ronald G Thurman
Dietary glycine and renal denervation prevents cyclosporin A-induced hydroxyl radical production in rat kidney.
Molecular pharmacology 1999;56(3):455-63.
1999: M Arai; Xing-Xi Peng; Robert T Currin; Ronald G Thurman; John J Lemasters
Protection of sinusoidal endothelial cells against storage/reperfusion injury by prostaglandin E2 derived from Kupffer cells.
Transplantation 1999;68(3):440-5.
1999: Zhi Zhong; Gavin E Arteel; Henry D Connor; Peter Schemmer; Shu-Chuan Chou; James Raleigh; Ronald P Mason; John J Lemasters; Ronald G Thurman
Binge drinking disturbs hepatic microcirculation after transplantation: prevention with free radical scavengers.
The Journal of pharmacology and experimental therapeutics 1999;290(2):611-20.
1999: Ronald G Thurman; Blair U Bradford; Yuji Iimuro; MV Frankenberg; KT Knecht; Henry D Connor; Y Adachi; C Wall; Gavin E Arteel; James Raleigh; Donald Forman; Ronald P Mason
Mechanisms of alcohol-induced hepatotoxicity: studies in rats.
Frontiers in bioscience : a journal and virtual library 1999;4():e42-6.
1999: Zhi Zhong; N Enomoto; Henry D Connor; Nicholas Moss; Ronald P Mason; Ronald G Thurman
Glycine improves survival after hemorrhagic shock in the rat.
Shock (Augusta, Ga.) 1999;12(1):54-62.
1999: Cynthia A Bradham; Peter Schemmer; Robert Stachlewitz; Ronald G Thurman; David A Brenner
Activation of nuclear factor-kappaB during orthotopic liver transplantation in rats is protective and does not require Kupffer cells.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1999;5(4):282-93.
1999: Peter Schemmer; Henry D Connor; Gavin E Arteel; James Raleigh; Hartwig Bunzendahl; R P Mason; Ronald G Thurman
Reperfusion injury in livers due to gentle in situ organ manipulation during harvest involves hypoxia and free radicals.
The Journal of pharmacology and experimental therapeutics 1999;290(1):235-40.
1999: N Enomoto; S Yamashina; Hiroshi Kono; Peter Schemmer; CA Rivera; A Enomoto; T Nishiura; T Nishimura; David A Brenner; Ronald G Thurman
Development of a new, simple rat model of early alcohol-induced liver injury based on sensitization of Kupffer cells.
Hepatology (Baltimore, Md.) 1999;29(6):1680-9.
1999: Peter Schemmer; Hartwig Bunzendahl; James Raleigh; Ronald G Thurman
Graft survival is improved by hepatic denervation before organ harvesting.
Transplantation 1999;67(10):1301-7.
1999: ML Rose; J Madren; Hartwig Bunzendahl; Ronald G Thurman
Dietary glycine inhibits the growth of B16 melanoma tumors in mice.
Carcinogenesis 1999;20(5):793-8.
1999: Peter Schemmer; Blair U Bradford; ML Rose; Hartwig Bunzendahl; James Raleigh; John J Lemasters; Ronald G Thurman
Intravenous glycine improves survival in rat liver transplantation.
The American journal of physiology 1999;276(4 Pt 1):G924-32.
1999: Gavin E Arteel; Maria B Kadiiska; Ivan Rusyn; Blair U Bradford; Ronald P Mason; James Raleigh; Ronald G Thurman
Oxidative stress occurs in perfused rat liver at low oxygen tension by mechanisms involving peroxynitrite.
Molecular pharmacology 1999;55(4):708-15.
1999: Kenichi Ikejima; N Enomoto; VITOR SEABRA; A Ikejima; David A Brenner; Ronald G Thurman
Pronase destroys the lipopolysaccharide receptor CD14 on Kupffer cells.
The American journal of physiology 1999;276(3 Pt 1):G591-8.
1999: Robert Stachlewitz; VITOR SEABRA; Blair U Bradford; Cynthia A Bradham; Ivan Rusyn; Dori R Germolec; Ronald G Thurman
Glycine and uridine prevent D-galactosamine hepatotoxicity in the rat: role of Kupffer cells.
Hepatology (Baltimore, Md.) 1999;29(3):737-45.
1999: Peter Schemmer; Hartwig Bunzendahl; John J Lemasters; Ronald G Thurman
Selective hepatic denervation prior to organ harvest improves survival after liver transplantation.
Transplantation proceedings 1999;31(1-2):537.
1999: M Arai; Ronald G Thurman; John J Lemasters
Involvement of Kupffer cells and sinusoidal endothelial cells in ischemic preconditioning to rat livers stored for transplantation.
Transplantation proceedings 1999;31(1-2):425-7.
1999: ML Rose; Ivan Rusyn; HK Bojes; Dori R Germolec; M Luster; Ronald G Thurman
Role of Kupffer cells in peroxisome proliferator-induced hepatocyte proliferation.
Drug metabolism reviews 1999;31(1):87-116.
1999: Peter Schemmer; Robert Schoonhoven; James A Swenberg; Hartwig Bunzendahl; James Raleigh; John J Lemasters; Ronald G Thurman
Gentle organ manipulation during harvest as a key determinant of survival of fatty livers after transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1999;12(5):351-9.
1999: M v Frankenberg; Robert Stachlewitz; Donald Forman; W Frey; Hartwig Bunzendahl; John J Lemasters; Ronald G Thurman
Amino acids in rinse effluents as a predictor of graft function after transplantation of fatty livers in rats.
Transplant international : official journal of the European Society for Organ Transplantation 1999;12(3):168-75.
1999: M L Rose; CA Rivera; Blair U Bradford; Lee M Graves; Russell C Cattley; Robert Schoonhoven; James A Swenberg; Ronald G Thurman
Kupffer cell oxidant production is central to the mechanism of peroxisome proliferators.
Carcinogenesis 1999;20(1):27-33.
1999: Blair U Bradford; N Enomoto; Kenichi Ikejima; ML Rose; HK Bojes; Donald Forman; Ronald G Thurman
Peroxisomes are involved in the swift increase in alcohol metabolism.
The Journal of pharmacology and experimental therapeutics 1999;288(1):254-9.
1998: Zhi Zhong; H D Connor; R P Mason; John J Lemasters; Ronald G Thurman
Ethanol, not fat accumulation per se, increases free radical production in a low-flow, reflow liver perfusion model.
Transplantation 1998;66(11):1431-8.
1998: CA Rivera; Blair U Bradford; VITOR SEABRA; Ronald G Thurman
Role of endotoxin in the hypermetabolic state after acute ethanol exposure.
The American journal of physiology 1998;275(6 Pt 1):G1252-8.
1998: VITOR SEABRA; Robert Stachlewitz; Ronald G Thurman
Taurine blunts LPS-induced increases in intracellular calcium and TNF-alpha production by Kupffer cells.
Journal of leukocyte biology 1998;64(5):615-21.
1998: CA Rivera; Michael D Wheeler; N Enomoto; Ronald G Thurman
A choline-rich diet improves survival in a rat model of endotoxin shock.
The American journal of physiology 1998;275(4 Pt 1):G862-7.
1998: Ronald G Thurman
II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin.
The American journal of physiology 1998;275(4 Pt 1):G605-11.
1998: S M Jones; Zhi Zhong; N Enomoto; Peter Schemmer; Ronald G Thurman
Dietary juniper berry oil minimizes hepatic reperfusion injury in the rat.
Hepatology (Baltimore, Md.) 1998;28(4):1042-50.
1998: Zhi Zhong; Gavin E Arteel; Henry D Connor; M Yin; MV Frankenberg; Robert Stachlewitz; James Raleigh; Ronald P Mason; Ronald G Thurman
Cyclosporin A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine.
The American journal of physiology 1998;275(4 Pt 2):F595-604.
1998: Ronald G Thurman; Blair U Bradford; Yuji Iimuro; KT Knecht; Gavin E Arteel; M Yin; Henry D Connor; C Wall; James Raleigh; MV Frankenberg; Y Adachi; Donald Forman; David A Brenner; Maria B Kadiiska; Ronald P Mason
The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury.
Journal of gastroenterology and hepatology 1998;13 Suppl():S39-50.
1998: W Qu; Zhi Zhong; Gavin E Arteel; Ronald G Thurman
Stimulation of oxygen uptake by prostaglandin E2 is oxygen dependent in perfused rat liver.
The American journal of physiology 1998;275(3 Pt 1):G542-9.
1998: M Yin; Kenichi Ikejima; Gavin E Arteel; VITOR SEABRA; Blair U Bradford; Hiroshi Kono; Ivan Rusyn; Ronald G Thurman
Glycine accelerates recovery from alcohol-induced liver injury.
The Journal of pharmacology and experimental therapeutics 1998;286(2):1014-9.
1998: N Enomoto; Kenichi Ikejima; Blair U Bradford; C Rivera; Hiroshi Kono; David A Brenner; Ronald G Thurman
Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin.
Gastroenterology 1998;115(2):443-51.
1998: Ivan Rusyn; H Tsukamoto; Ronald G Thurman
WY-14 643 rapidly activates nuclear factor kappaB in Kupffer cells before hepatocytes.
Carcinogenesis 1998;19(7):1217-22.
1998: H D Connor; Ronald G Thurman; G Chen; J L Poyer; EG Janzen; Ronald P Mason
Clarification of the relationship between free radical spin trapping and carbon tetrachloride metabolism in microsomal systems.
Free radical biology & medicine 1998;24(9):1364-8.
1998: Gavin E Arteel; Ronald G Thurman; James Raleigh
Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state.
European journal of biochemistry / FEBS 1998;253(3):743-50.
1998: Peter Schemmer; Robert Schoonhoven; James A Swenberg; Hartwig Bunzendahl; Ronald G Thurman
Gentle in situ liver manipulation during organ harvest decreases survival after rat liver transplantation: role of Kupffer cells.
Transplantation 1998;65(8):1015-20.
1998: Kenichi Ikejima; N Enomoto; Yuji Iimuro; A Ikejima; D Fang; J Xu; Donald Forman; David A Brenner; Ronald G Thurman
Estrogen increases sensitivity of hepatic Kupffer cells to endotoxin.
The American journal of physiology 1998;274(4 Pt 1):G669-76.
1998: Peter Schemmer; Hartwig Bunzendahl; Ronald G Thurman
[Preparing the donor with glycine improves survival after liver transplantation in the animal model].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115(Suppl I):589-93.
1998: MV Frankenberg; Donald Forman; W Frey; Hartwig Bunzendahl; Ronald G Thurman
[Proteolysis but not ICAM-1 expression in fatty liver increased in tissue harvesting--role of Kupffer cells].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115(Suppl I):575-9.
1998: Ronald G Thurman; Peter Schemmer; Zhi Zhong; Hartwig Bunzendahl; M von Frankenberg; John J Lemasters
Kupffer cell-dependent reperfusion injury in liver transplantation: new clinically relevant use of glycine.
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115():185-90.
1998: Robert Stachlewitz; W Gao; Zhi Zhong; Henry D Connor; Ronald P Mason; Ronald G Thurman
Generation of lipid free radicals by adherent leukocytes from transplanted rat liver.
Transplant international : official journal of the European Society for Organ Transplantation 1998;11(5):353-60.
1997: Yuji Iimuro; RM Gallucci; Michael I Luster; Hiroshi Kono; Ronald G Thurman
Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat.
Hepatology (Baltimore, Md.) 1997;26(6):1530-7.
1997: Zhi Zhong; Henry D Connor; Robert Stachlewitz; MV Frankenberg; Ronald P Mason; John J Lemasters; Ronald G Thurman
Role of free radicals in primary nonfunction of marginal fatty grafts from rats treated acutely with ethanol.
Molecular pharmacology 1997;52(5):912-9.
1997: ML Rose; Dori R Germolec; Gavin E Arteel; Robert Schoonhoven; Ronald G Thurman
Dietary glycine prevents increases in hepatocyte proliferation caused by the peroxisome proliferator WY-14,643.
Chemical research in toxicology 1997;10(10):1198-204.
1997: Robert Stachlewitz; Gavin E Arteel; James Raleigh; Henry D Connor; Ronald P Mason; Ronald G Thurman
Development and characterization of a new model of tacrine-induced hepatotoxicity: role of the sympathetic nervous system and hypoxia-reoxygenation.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1591-9.
1997: ML Rose; Dori R Germolec; Robert Schoonhoven; Ronald G Thurman
Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators.
Carcinogenesis 1997;18(8):1453-6.
1997: M von Frankenberg; Donald Forman; W Frey; Robert Stachlewitz; Hartwig Bunzendahl; Ronald G Thurman
Release of amino acids from fatty livers during organ harvest for transplantation.
Annals of clinical and laboratory science 1997;27(4):287-92.
1997: Ronald G Thurman; Zhi Zhong; M von Frankenberg; Robert Stachlewitz; Hartwig Bunzendahl
Prevention of cyclosporine-induced nephrotoxicity with dietary glycine.
Transplantation 1997;63(11):1661-7.
1997: Kenichi Ikejima; W Qu; Robert Stachlewitz; Ronald G Thurman
Kupffer cells contain a glycine-gated chloride channel.
The American journal of physiology 1997;272(6 Pt 1):G1581-6.
1997: Yuji Iimuro; MV Frankenberg; Gavin E Arteel; Blair U Bradford; C A Wall; Ronald G Thurman
Female rats exhibit greater susceptibility to early alcohol-induced liver injury than males.
The American journal of physiology 1997;272(5 Pt 1):G1186-94.
1997: Ronald G Thurman; Blair U Bradford; Yuji Iimuro; KT Knecht; Henry D Connor; Y Adachi; C Wall; Gavin E Arteel; James Raleigh; Donald Forman; Ronald P Mason
Role of Kupffer cells, endotoxin and free radicals in hepatotoxicity due to prolonged alcohol consumption: studies in female and male rats.
The Journal of nutrition 1997;127(5 Suppl):903S-906S.
1997: Cynthia A Bradham; Robert Stachlewitz; W Gao; Ting Qian; Supriya Jayadev; G Jenkins; Yusuf A Hannun; John J Lemasters; Ronald G Thurman; David A Brenner
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases.
Hepatology (Baltimore, Md.) 1997;25(5):1128-35.
1997: HK Bojes; Dori R Germolec; Petia P Simeonova; Alessandra Bruccoleri; Robert Schoonhoven; Michael I Luster; Ronald G Thurman
Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643.
Carcinogenesis 1997;18(4):669-74.
1997: Gavin E Arteel; Yuji Iimuro; M Yin; James Raleigh; Ronald G Thurman
Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo.
Hepatology (Baltimore, Md.) 1997;25(4):920-6.
1997: HK Bojes; ML Rose; B J Keller; Dori R Germolec; Petia P Simeonova; Michael I Luster; Ronald G Thurman
Mitogenic actions of peroxidase proliferators: involvement of protein kinase C and tumor necrosis factor alpha.
Drug metabolism reviews 1997;29(1-2):235-60.
1997: MV Frankenberg; Donald Forman; W Frey; Hartwig Bunzendahl; John J Lemasters; Ronald G Thurman
Amino acids in storage solution predict primary nonfunction in fatty liver grafts.
Transplantation proceedings 1997;29(1-2):1331-2.
1997: John J Lemasters; Ronald G Thurman
Reperfusion injury after liver preservation for transplantation.
Annual review of pharmacology and toxicology 1997;37():327-38.
1997: Alessandra Bruccoleri; RM Gallucci; Dori R Germolec; Perry Blackshear; Petia P Simeonova; Ronald G Thurman; Michael I Luster
Induction of early-immediate genes by tumor necrosis factor alpha contribute to liver repair following chemical-induced hepatotoxicity.
Hepatology (Baltimore, Md.) 1997;25(1):133-41.
1996: R T Currin; J C Caldwell-Kenkel; Steven N Lichtman; S Bachmann; Y Takei; S Kawano; Ronald G Thurman; John J Lemasters
Protection by Carolina rinse solution, acidotic pH, and glycine against lethal reperfusion injury to sinusoidal endothelial cells of rat livers stored for transplantation.
Transplantation 1996;62(11):1549-58.
1996: HK Bojes; Ronald G Thurman
Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver.
Toxicology and applied pharmacology 1996;140(2):322-7.
1996: Zhi Zhong; H Connor; Ronald P Mason; W Qu; Robert Stachlewitz; W Gao; John J Lemasters; Ronald G Thurman
Destruction of Kupffer cells increases survival and reduces graft injury after transplantation of fatty livers from ethanol-treated rats.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1996;2(5):383-7.
1996: Gavin E Arteel; James Raleigh; Blair U Bradford; Ronald G Thurman
Acute alcohol produces hypoxia directly in rat liver tissue in vivo: role of Kupffer cells.
The American journal of physiology 1996;271(3 Pt 1):G494-500.
1996: Yuji Iimuro; Blair U Bradford; W Gao; Maria B Kadiiska; Ronald P Mason; Branko Stefanovic; David A Brenner; Ronald G Thurman
Detection of alpha-hydroxyethyl free radical adducts in the pancreas after chronic exposure to alcohol in the rat.
Molecular pharmacology 1996;50(3):656-61.
1996: Yuji Iimuro; Kenichi Ikejima; ML Rose; Blair U Bradford; Ronald G Thurman
Nimodipine, a dihydropyridine-type calcium channel blocker, prevents alcoholic hepatitis caused by chronic intragastric ethanol exposure in the rat.
Hepatology (Baltimore, Md.) 1996;24(2):391-7.
1996: Kenichi Ikejima; Yuji Iimuro; Donald Forman; Ronald G Thurman
A diet containing glycine improves survival in endotoxin shock in the rat.
The American journal of physiology 1996;271(1 Pt 1):G97-103.
1996: S M Jones; Ronald G Thurman
L-arginine minimizes reperfusion injury in a low-flow, reflow model of liver perfusion.
Hepatology (Baltimore, Md.) 1996;24(1):163-8.
1996: Yuji Iimuro; Blair U Bradford; Donald Forman; Ronald G Thurman
Glycine prevents alcohol-induced liver injury by decreasing alcohol in the rat stomach.
Gastroenterology 1996;110(5):1536-42.
1996: W Qu; Zhi Zhong; M Goto; Ronald G Thurman
Kupffer cell prostaglandin E2 stimulates parenchymal cell O2 consumption: alcohol and cell-cell communication.
The American journal of physiology 1996;270(4 Pt 1):G574-80.
1996: HK Bojes; P J Sausen; Russell C Cattley; B J Keller; Ronald G Thurman
Paradoxical increase in peroxisomal cyanide-insensitive respiration following dietary exposure to WY-14,643 in the perfused liver.
Toxicology and applied pharmacology 1996;137(2):202-9.
1996: Zhi Zhong; S Jones; Ronald G Thurman
Glycine minimizes reperfusion injury in a low-flow, reflow liver perfusion model in the rat.
The American journal of physiology 1996;270(2 Pt 1):G332-8.
1996: Ronald G Thurman; W Gao; Henry D Connor; Y Adachi; Robert Stachlewitz; Zhi Zhong; K T Knecht; Blair U Bradford; Ronald P Mason; John J Lemasters
Role of free radicals in failure of fatty livers following liver transplantation and alcoholic liver injury.
Advances in experimental medicine and biology 1996;387():231-41.
1996: HK Bojes; Ronald G Thurman
Peroxisome proliferators activate Kupffer cells in vivo.
Cancer research 1996;56(1):1-4.
1995: Zhi Zhong; Henry D Connor; Ronald P Mason; W Qu; W Gao; John J Lemasters; Ronald G Thurman
Role of Kupffer cells in reperfusion injury in fat-loaded livers from ethanol-treated rats.
The Journal of pharmacology and experimental therapeutics 1995;275(3):1512-7.
1995: József Mandl; C Wall; István Léránt; András Falus; Raymund Machovich; Ronald G Thurman
Endotoxin and fibrinogen degradation product-D have different actions on carbohydrate metabolism: role of Kupffer cells.
FEBS letters 1995;376(1-2):65-6.
1995: Gavin E Arteel; Ronald G Thurman; J M Yates; James Raleigh
Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver.
British journal of cancer 1995;72(4):889-95.
1995: Zhi Zhong; Ronald G Thurman
A fish oil diet minimizes hepatic reperfusion injury in the low-flow, reflow liver perfusion model.
Hepatology (Baltimore, Md.) 1995;22(3):929-35.
1995: X X Peng; R T Currin; Ronald G Thurman; John J Lemasters
Protection by pentoxifylline against normothermic liver ischemia/reperfusion in rats.
Transplantation 1995;59(11):1537-41.
1995: W Qu; F C Kauffman; Ronald G Thurman
Food restriction stimulates conjugation of p-nitrophenol in perfused rat liver.
Archives of biochemistry and biophysics 1995;319(2):451-6.
1995: K T Knecht; Y Adachi; Blair U Bradford; Yuji Iimuro; Maria B Kadiiska; Q H Xuang; Ronald G Thurman
Free radical adducts in the bile of rats treated chronically with intragastric alcohol: inhibition by destruction of Kupffer cells.
Molecular pharmacology 1995;47(5):1028-34.
1995: W Gao; Henry D Connor; John J Lemasters; Ronald P Mason; Ronald G Thurman
Primary nonfunction of fatty livers produced by alcohol is associated with a new, antioxidant-insensitive free radical species.
Transplantation 1995;59(5):674-9.
1995: John J Lemasters; Hartwig Bunzendahl; Ronald G Thurman
Reperfusion injury to donor livers stored for transplantation.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1995;1(2):124-38.
1995: S Bachmann; X X Peng; R T Currin; Ronald G Thurman; John J Lemasters
Glycine in Carolina rinse solution reduces reperfusion injury, improves graft function, and increases graft survival after rat liver transplantation.
Transplantation proceedings 1995;27(1):741-2.
1995: Zhi Zhong; W Qu; Henry D Connor; Ronald G Thurman
Inactivation of Kupffer cells minimizes reperfusion injury in fat-loaded livers from ethanol-treated rats.
Transplantation proceedings 1995;27(1):528-30.
1995: John J Lemasters; X X Peng; S Bachmann; R T Currin; W Gao; Ronald G Thurman
Dual role of Kupffer cell activation and endothelial cell damage in reperfusion injury to livers stored for transplantation surgery.
Journal of gastroenterology and hepatology 1995;10 Suppl 1():S84-7.
1995: Ronald G Thurman; W Gao; Henry D Connor; Y Adachi; Robert Stachlewitz; Zhi Zhong; K T Knecht; Blair U Bradford; Ronald P Mason; John J Lemasters
Role of Kupffer cells in failure of fatty livers following liver transplantation and alcoholic liver injury.
Journal of gastroenterology and hepatology 1995;10 Suppl 1():S24-30.
1995: Y Adachi; L E Moore; Blair U Bradford; W Gao; Ronald G Thurman
Antibiotics prevent liver injury in rats following long-term exposure to ethanol.
Gastroenterology 1995;108(1):218-24.
1995: J C Caldwell-Kenkel; R T Currin; A Coote; Ronald G Thurman; John J Lemasters
Reperfusion injury to endothelial cells after cold storage of rat livers: protection by mildly acidic pH and lack of protection by antioxidants.
Transplant international : official journal of the European Society for Organ Transplantation 1995;8(2):77-85.
1994: T Fusaoka; K J Hunt; John J Lemasters; Ronald G Thurman
Evidence that activation of Kupffer cells increases oxygen uptake after cold storage.
Transplantation 1994;58(10):1067-71.
1994: C Bremer; Blair U Bradford; K J Hunt; K T Knecht; Henry D Connor; Ronald P Mason; Ronald G Thurman
Role of Kupffer cells in the pathogenesis of hepatic reperfusion injury.
The American journal of physiology 1994;267(4 Pt 1):G630-6.
1994: H Oide; Ronald G Thurman
Hepatic Ito cells contain calcium channels: increases with transforming growth factor-beta 1.
Hepatology (Baltimore, Md.) 1994;20(4 Pt 1):1009-14.
1994: Zhi Zhong; M Goto; T Hijioka; H Oide; F C Kauffman; Ronald G Thurman
Role of Kupffer cells in storage and metabolism of benzo(a)pyrene in the liver.
Drug metabolism and disposition: the biological fate of chemicals 1994;22(5):680-7.
1994: Y Adachi; Blair U Bradford; W Gao; HK Bojes; Ronald G Thurman
Inactivation of Kupffer cells prevents early alcohol-induced liver injury.
Hepatology (Baltimore, Md.) 1994;20(2):453-60.
1994: W Qu; F C Kauffman; Ronald G Thurman
Food restriction and stimulation of monooxygenation of p-nitroanisole in perfused rat liver.
Biochemical pharmacology 1994;48(2):311-7.
1994: HK Bojes; Ronald G Thurman
Peroxisomal proliferators inhibit acyl CoA synthetase and stimulate protein kinase C in vivo.
Toxicology and applied pharmacology 1994;126(2):233-9.
1994: L J Reinstein; Steven N Lichtman; R T Currin; J Wang; Ronald G Thurman; John J Lemasters
Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: evidence for A2 receptors on rat Kupffer cells.
Hepatology (Baltimore, Md.) 1994;19(6):1445-52.
1994: Henry D Connor; W Gao; Ronald P Mason; Ronald G Thurman
New reactive oxidizing species causes formation of carbon-centered radical adducts in organic extracts of blood following liver transplantation.
Free radical biology & medicine 1994;16(6):871-5.
1994: Y Nakagawa; T Matsumura; M Goto; W Qu; F C Kauffman; Ronald G Thurman
Increase in oxygen uptake due to arachidonic acid is oxygen dependent in the perfused liver.
The American journal of physiology 1994;266(5 Pt 1):G953-9.
1994: K J Hunt; John J Lemasters; Ronald G Thurman
High concentrations of adenosine are needed in Carolina rinse to prevent activation of Kupffer cells.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S493-5.
1994: E Savier; John J Lemasters; Ronald G Thurman
Kupffer cells participate in rejection following liver transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S183-6.
1994: Ronald G Thurman; W Gao; Henry D Connor; Ronald P Mason; John J Lemasters; H Bozigian; Laurel M Adams
SPC-100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S167-70.
1994: S Nukina; T Fusaoka; Ronald G Thurman
Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells.
The American journal of physiology 1994;266(1 Pt 1):G99-105.
1993: M Goto; John J Lemasters; Ronald G Thurman
Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1264-8.
1993: T Hijioka; M Goto; John J Lemasters; Ronald G Thurman
Effect of short-term ethanol treatment on voltage-dependent calcium channels in Kupffer cells.
Hepatology (Baltimore, Md.) 1993;18(2):400-5.
1993: W Gao; John J Lemasters; Ronald G Thurman
Development of a new method for hepatic rearterialization in rat orthotopic liver transplantation. Reduction of liver injury and improvement of surgical outcome by arterialization.
Transplantation 1993;56(1):19-24.
1993: K T Knecht; Ronald G Thurman; Ronald P Mason
Role of superoxide and trace transition metals in the production of alpha-hydroxyethyl radical from ethanol by microsomes from alcohol dehydrogenase-deficient deermice.
Archives of biochemistry and biophysics 1993;303(2):339-48.
1993: Blair U Bradford; C B Seed; J A Handler; Donald Forman; Ronald G Thurman
Evidence that catalase is a major pathway of ethanol oxidation in vivo: dose-response studies in deer mice using methanol as a selective substrate.
Archives of biochemistry and biophysics 1993;303(1):172-6.
1993: M J Edwards; B J Keller; F C Kauffman; Ronald G Thurman
The involvement of Kupffer cells in carbon tetrachloride toxicity.
Toxicology and applied pharmacology 1993;119(2):275-9.
1993: B J Keller; Blair U Bradford; D S Marsman; Russell C Cattley; J A Popp; HK Bojes; Ronald G Thurman
The nongenotoxic hepatocarcinogen Wy-14,643 is an uncoupler of oxidative phosphorylation in vivo.
Toxicology and applied pharmacology 1993;119(1):52-8.
1993: Ronald G Thurman; Hartwig Bunzendahl; John J Lemasters
Role of sinusoidal lining cells in hepatic reperfusion injury following cold storage and transplantation.
Seminars in liver disease 1993;13(1):93-100.
1993: R T Currin; L J Reinstein; Steven N Lichtman; Ronald G Thurman; John J Lemasters
Inhibition of tumor necrosis factor release from cultured rat Kupffer cells by agents that reduce graft failure from storage injury.
Transplantation proceedings 1993;25(1 Pt 2):1631-2.
1993: S Bachmann; J C Caldwell-Kenkel; R T Currin; Y Tanaka; Y Takei; I Marzi; Ronald G Thurman; John J Lemasters
Ultrastructural correlates of liver graft failure from storage injury: studies of graft protection by Carolina rinse solution and pentoxifylline.
Transplantation proceedings 1993;25(1 Pt 2):1620-4.
1993: Blair U Bradford; Donald Forman; Ronald G Thurman
4-Methylpyrazole inhibits fatty acyl coenzyme synthetase and diminishes catalase-dependent alcohol metabolism: has the contribution of alcohol dehydrogenase to alcohol metabolism been previously overestimated?
Molecular pharmacology 1993;43(1):115-9.
1993: J J Lemaster; Ronald G Thurman
Hypoxia and reperfusion injury to liver.
Progress in liver diseases 1993;11():85-114.
1992: D Liang; Ronald G Thurman
Protective effects of the calcium antagonists diltiazem and TA3090 against hepatic injury due to hypoxia.
Biochemical pharmacology 1992;44(11):2207-11.
1992: Y Liu; Ronald G Thurman
Potentiation of adriamycin toxicity by ethanol in perfused rat liver.
The Journal of pharmacology and experimental therapeutics 1992;263(2):651-6.
1992: U K Misra; Blair U Bradford; J A Handler; Ronald G Thurman
Chronic ethanol treatment induces H2O2 production selectively in pericentral regions of the liver lobule.
Alcoholism, clinical and experimental research 1992;16(5):839-42.
1992: B J Keller; D S Marsman; J A Popp; Ronald G Thurman
Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation.
Biochimica et biophysica acta 1992;1102(2):237-44.
1992: H Yamanaka; S Nukina; J A Handler; R T Currin; John J Lemasters; Ronald G Thurman
Transient activation of hepatic glycogenolysis by thrombin in perfused rat livers.
European journal of biochemistry / FEBS 1992;208(3):753-9.
1992: HK Bojes; B J Keller; Ronald G Thurman
Wy-14,643 stimulates hepatic protein kinase C activity.
Toxicology letters 1992;62(2-3):317-22.
1992: Henry D Connor; W Gao; S Nukina; John J Lemasters; Ronald P Mason; Ronald G Thurman
Evidence that free radicals are involved in graft failure following orthotopic liver transplantation in the rat--an electron paramagnetic resonance spin trapping study.
Transplantation 1992;54(2):199-204.
1992: W Qu; E Savier; Ronald G Thurman
Stimulation of monooxygenation and conjugation after liver transplantation in the rat: involvement of Kupffer cells.
Molecular pharmacology 1992;41(6):1149-54.
1992: S Bachmann; J C Caldwell-Kenkel; I Oleksy; R Steffen; Ronald G Thurman; John J Lemasters
Warm Carolina rinse solution prevents graft failure from storage injury after orthotopic rat liver transplantation with arterialization.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5(2):108-14.
1992: K L Wall; W Gao; W Qu; G Kwei; F C Kauffman; Ronald G Thurman
Food restriction increases detoxification of polycyclic aromatic hydrocarbons in the rat.
Carcinogenesis 1992;13(4):519-23.
1992: T Matsumura; H Yoshihara; R Jeffs; Y Takei; S Nukina; T Hijioka; R K Evans; F C Kauffman; Ronald G Thurman
Hormones increase oxygen uptake in periportal and pericentral regions of the liver lobule.
The American journal of physiology 1992;262(4 Pt 1):G645-50.
1992: G Y Kwei; J Zaleski; S E Irwin; Ronald G Thurman; F C Kauffman
Conjugation of benzo(a)pyrene 7,8-dihydrodiol-9,10-epoxide in infant Swiss-Webster mice.
Cancer research 1992;52(6):1639-42.
1992: T Hijioka; R L Rosenberg; John J Lemasters; Ronald G Thurman
Kupffer cells contain voltage-dependent calcium channels.
Molecular pharmacology 1992;41(3):435-40.
1992: K A Lindert; J C Caldwell-Kenkel; S Nukina; John J Lemasters; Ronald G Thurman
Activation of Kupffer cells on reperfusion following hypoxia: particle phagocytosis in a low-flow, reflow model.
The American journal of physiology 1992;262(2 Pt 1):G345-50.
1992: E Savier; Steven I Shedlofsky; A T Swim; John J Lemasters; Ronald G Thurman
The calcium channel blocker nisoldipine minimizes the release of tumor necrosis factor and interleukin-6 following rat liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S398-402.
1992: W Gao; John J Lemasters; Ronald G Thurman
The second generation of Carolina Rinse, solution II, improves graft survival following orthotopic liver transplantation in the rat by preventing reperfusion injury.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S362-5.
1992: S Bachmann; J C Caldwell-Kenkel; R T Currin; Steven N Lichtman; R Steffen; Ronald G Thurman; John J Lemasters
Protection by pentoxifylline against graft failure from storage injury after orthotopic rat liver transplantation with arterialization.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S345-50.
1992: W Gao; R J Currin; John J Lemasters; Henry D Connor; Ronald P Mason; Ronald G Thurman
Reperfusion rather than storage injury predominates following long-term (48 h) cold storage of grafts in UW solution: studies with Carolina Rinse in transplanted rat liver.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S329-35.
1992: B J Keller; H Yamanaka; Ronald G Thurman
Inhibition of mitochondrial respiration and oxygen-dependent hepatotoxicity by six structurally dissimilar peroxisomal proliferating agents.
Toxicology 1992;71(1-2):49-61.
1992: S E Irwin; G Y Kwei; Gary Blackburn; Ronald G Thurman; F C Kauffman
Mutagenicity of benzo(a)pyrenyl-1-sulfate in the Ames test.
Environmental and molecular mutagenesis 1992;19(3):253-8.
1992: J A Handler; C B Seed; Blair U Bradford; Ronald G Thurman
Induction of peroxisomes by treatment with perfluorooctanoate does not increase rates of H2O2 production in intact liver.
Toxicology letters 1992;60(1):61-8.
1991: I Marzi; K Cowper; Y Takei; K Lindert; John J Lemasters; Ronald G Thurman
Methyl palmitate prevents Kupffer cell activation and improves survival after orthotopic liver transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1991;4(4):215-20.
1991: T Hijioka; B J Keller; Ronald G Thurman
Wy-14,643 but not 2-ethylhexanol increases intracellular free calcium in cultured Kupffer cells.
Toxicology letters 1991;59(1-3):239-44.
1991: W S Gao; T Hijioka; K A Lindert; J C Caldwell-Kenkel; John J Lemasters; Ronald G Thurman
Evidence that adenosine is a key component in Carolina rinse responsible for reducing graft failure after orthotopic liver transplantation in the rat.
Transplantation 1991;52(6):992-8.
1991: J Zaleski; G Y Kwei; Ronald G Thurman; F C Kauffman
Suppression of benzo[a]pyrene metabolism by accumulation of triacylglycerols in rat hepatocytes: effect of high-fat and food-restricted diets.
Carcinogenesis 1991;12(11):2073-9.
1991: Zhi Zhong; F C Kauffman; Ronald G Thurman
Inhibition of glucuronidation of benzo(a)pyrene phenols by long-chain fatty acids.
Cancer research 1991;51(17):4511-5.
1991: W S Gao; Y Takei; I Marzi; K A Lindert; J C Caldwell-Kenkel; R T Currin; Y Tanaka; John J Lemasters; Ronald G Thurman
Carolina rinse solution--a new strategy to increase survival time after orthotopic liver transplantation in the rat.
Transplantation 1991;52(3):417-24.
1991: Blair U Bradford; J A Handler; C B Seed; Donald Forman; Ronald G Thurman
Inhibition of ethanol metabolism by fructose in alcohol dehydrogenase-deficient deer mice in vivo.
Archives of biochemistry and biophysics 1991;288(2):435-9.
1991: Y Takei; W S Gao; T Hijioka; E Savier; K A Lindert; John J Lemasters; Ronald G Thurman
Increase in survival of liver grafts after rinsing with warm Ringer's solution due to improvement of hepatic microcirculation.
Transplantation 1991;52(2):225-30.
1991: Johan teKoppele; B J Keller; J C Caldwell-Kenkel; John J Lemasters; Ronald G Thurman
Effect of hepatotoxic chemicals and hypoxia on hepatic nonparenchymal cells: impairment of phagocytosis by Kupffer cells and disruption of the endothelium in rat livers perfused with colloidal carbon.
Toxicology and applied pharmacology 1991;110(1):20-30.
1991: B J Keller; D Liang; Ronald G Thurman
2-Ethylhexanol uncouples oxidative phosphorylation in rat liver mitochondria.
Toxicology letters 1991;57(1):113-20.
1991: Y Takei; I Marzi; W S Gao; G J Gores; John J Lemasters; Ronald G Thurman
Leukocyte adhesion and cell death following orthotopic liver transplantation in the rat.
Transplantation 1991;51(5):959-65.
1991: K L Wall; W S Gao; Johan teKoppele; G Y Kwei; F C Kauffman; Ronald G Thurman
The liver plays a central role in the mechanism of chemical carcinogenesis due to polycyclic aromatic hydrocarbons.
Carcinogenesis 1991;12(5):783-6.
1991: Patricia E Ganey; Ronald G Thurman
Ethanol potentiates doxorubicin-induced inhibition of cell survival in cultured Chinese hamster ovary cells.
Cancer research 1991;51(8):2036-40.
1991: F C Kauffman; M Whittaker; I Anundi; Ronald G Thurman
Futile cycling of a sulfate conjugate by isolated hepatocytes.
Molecular pharmacology 1991;39(3):414-20.
1991: Patricia E Ganey; B Keller; Steven N Lichtman; John J Lemasters; Ronald G Thurman
A new method to monitor Kupffer cell phagocytosis continuously in perfused rat liver.
Hepatology (Baltimore, Md.) 1991;13(3):567-74.
1991: R T Currin; G J Gores; Ronald G Thurman; John J Lemasters
Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(2):207-10.
1991: D C Liang; B J Keller; U K Misra; Ronald G Thurman
Oxygen tension is a major determinant of hepatotoxicity due to 2-ethylhexanol in isolated tissue cylinders from periportal and pericentral regions of the liver lobule from phenobarbital-treated rats.
Toxicology and applied pharmacology 1991;107(2):344-9.
1991: W Gao; Y Takei; I Marzi; R T Currin; John J Lemasters; Ronald G Thurman
Carolina rinse solution increases survival time dramatically after orthotopic liver transplantation in the rat.
Transplantation proceedings 1991;23(1 Pt 1):648-50.
1991: R T Currin; Ronald G Thurman; John J Lemasters
Carolina rinse solution protects adenosine triphosphate-depleted hepatocytes against lethal cell injury.
Transplantation proceedings 1991;23(1 Pt 1):645-7.
1991: J C Caldwell-Kenkel; R T Currin; Y Tanaka; Ronald G Thurman; John J Lemasters
Kupffer cell activation and endothelial cell damage after storage of rat livers: effects of reperfusion.
Hepatology (Baltimore, Md.) 1991;13(1):83-95.
1991: G Y Kwei; J Zaleski; Ronald G Thurman; F C Kauffman
Enzyme activities associated with carcinogen metabolism in liver and nonhepatic tissues of rats maintained on high fat and food-restricted diets.
The Journal of nutrition 1991;121(1):131-7.
1990: T Sugano; J A Handler; H Yoshihara; Z Kizaki; Ronald G Thurman
Acute and chronic ethanol treatment in vivo increases malate-aspartate shuttle capacity in perfused rat liver.
The Journal of biological chemistry 1990;265(35):21549-53.
1990: Patricia E Ganey; Y Takei; F C Kauffman; Ronald G Thurman
Ethanol potentiates oxygen uptake and toxicity due to menadione bisulfite in perfused rat liver.
Molecular pharmacology 1990;38(6):959-64.
1990: R T Currin; J G Toole; Ronald G Thurman; John J Lemasters
Evidence that Carolina rinse solution protects sinusoidal endothelial cells against reperfusion injury after cold ischemic storage of rat liver.
Transplantation 1990;50(6):1076-8.
1990: Johan teKoppele; Ronald G Thurman
Phagocytosis by Kupffer cells predominates in pericentral regions of the liver lobule.
The American journal of physiology 1990;259(5 Pt 1):G814-21.
1990: Y Takei; I Marzi; F C Kauffman; K Cowper; John J Lemasters; Ronald G Thurman
Prevention of early graft failure by the calcium channel blocker nisoldipine: involvement of Kupffer cells.
Transplantation proceedings 1990;22(5):2202-3.
1990: Y R Wu; F C Kauffman; W Qu; Patricia E Ganey; Ronald G Thurman
Unique role of oxygen in regulation of hepatic monooxygenation and glucuronidation.
Molecular pharmacology 1990;38(1):128-33.
1990: Y Takei; I Marzi; F C Kauffman; R T Currin; John J Lemasters; Ronald G Thurman
Increase in survival time of liver transplants by protease inhibitors and a calcium channel blocker, nisoldipine.
Transplantation 1990;50(1):14-20.
1990: B J Keller; H Yamanaka; D C Liang; Ronald G Thurman
Hepatotoxicity due to clofibrate is oxygen-dependent in the perfused rat liver.
Toxicology and applied pharmacology 1990;104(2):259-66.
1990: B J Keller; H Yamanaka; D C Liang; F C Kauffman; Ronald G Thurman
O2-dependent hepatotoxicity due to ethylhexanol in the perfused rat liver: mitochondria as a site of action.
The Journal of pharmacology and experimental therapeutics 1990;252(3):1355-60.
1990: Henry D Connor; L B Lacagnin; K T Knecht; Ronald G Thurman; Ronald P Mason
Reaction of glutathione with a free radical metabolite of carbon tetrachloride.
Molecular pharmacology 1990;37(3):443-51.
1990: K B Cowper; R T Currin; Tom Dawson; K A Lindert; John J Lemasters; Ronald G Thurman
A new method to monitor Kupffer-cell function continuously in the perfused rat liver. Dissociation of glycogenolysis from particle phagocytosis.
The Biochemical journal 1990;266(1):141-7.
1990: M Z Badr; J A Handler; M Whittaker; F C Kauffman; Ronald G Thurman
Interactions between plasticizers and fatty acid metabolism in the perfused rat liver and in vivo. Inhibition of ketogenesis by 2-ethylhexanol.
Biochemical pharmacology 1990;39(4):715-21.
1990: J A Handler; Ronald G Thurman
Redox interactions between catalase and alcohol dehydrogenase pathways of ethanol metabolism in the perfused rat liver.
The Journal of biological chemistry 1990;265(3):1510-5.
1989: I Marzi; Zhi Zhong; John J Lemasters; Ronald G Thurman
Evidence that graft survival is not related to parenchymal cell viability in rat liver transplantation. The importance of nonparenchymal cells.
Transplantation 1989;48(3):463-8.
1989: J C Caldwell-Kenkel; R T Currin; Y Tanaka; Ronald G Thurman; John J Lemasters
Reperfusion injury to endothelial cells following cold ischemic storage of rat livers.
Hepatology (Baltimore, Md.) 1989;10(3):292-9.
1989: Zhi Zhong; John J Lemasters; Ronald G Thurman
Role of purines and xanthine oxidase in reperfusion injury in perfused rat liver.
The Journal of pharmacology and experimental therapeutics 1989;250(2):470-5.
1989: I Anundi; F C Kauffman; Johan teKoppele; H Yamanaka; M Whittaker; J A Popp; Ronald G Thurman
Adenine nucleotides and carbohydrates in subpopulations of hepatic nodules with normal and compromised microcirculation.
Cancer research 1989;49(12):3282-6.
1989: Zhi Zhong; W Gao; F C Kauffman; Ronald G Thurman
Effect of fatty acids on formation, distribution, storage, and release of benzo(a)pyrene phenols and glucuronides in the isolated perfused rat liver.
Cancer research 1989;49(8):2012-6.
1989: S A Belinsky; F C Kauffman; Ronald G Thurman
Interactions between glycolysis and mixed function oxidation: studies with 7-ethoxycoumarin in perfused livers from beta-naphthoflavone-treated rats.
Molecular pharmacology 1989;35(4):512-8.
1989: M Z Badr; Patricia E Ganey; H Yoshihara; F C Kauffman; Ronald G Thurman
Hepatotoxicity of menadione predominates in oxygen-rich zones of the liver lobule.
The Journal of pharmacology and experimental therapeutics 1989;248(3):1317-22.
1989: Z Kizaki; Ronald G Thurman
Stimulation of oxygen uptake by glucagon is oxygen dependent in perfused rat liver.
The American journal of physiology 1989;256(2 Pt 1):G369-76.
1989: I Marzi; Z N Zhi; F A Zimmermann; John J Lemasters; Ronald G Thurman
Xanthine and hypoxanthine accumulation during storage may contribute to reperfusion injury following liver transplantation in the rat.
Transplantation proceedings 1989;21(1 Pt 2):1319-20.
1988: Patricia E Ganey; F C Kauffman; Ronald G Thurman
Oxygen-dependent hepatotoxicity due to doxorubicin: role of reducing equivalent supply in perfused rat liver.
Molecular pharmacology 1988;34(5):695-701.
1988: Ronald G Thurman; I Marzi; G Seitz; J Thies; John J Lemasters; F Zimmerman
Hepatic reperfusion injury following orthotopic liver transplantation in the rat.
Transplantation 1988;46(4):502-6.
1988: J A Handler; Ronald G Thurman
Hepatic ethanol metabolism is mediated predominantly by catalase-H2O2 in the fasted state.
FEBS letters 1988;238(1):139-41.
1988: J A Handler; Ronald G Thurman
Catalase-dependent ethanol oxidation in perfused rat liver. Requirement for fatty-acid-stimulated H2O2 production by peroxisomes.
European journal of biochemistry / FEBS 1988;176(2):477-84.
1988: M R Schön; F C Kauffman; Ronald G Thurman
Selective depletion and measurement of glutathione in periportal and pericentral regions in the perfused rat liver.
Toxicology letters 1988;42(3):265-72.
1988: J A Handler; Dennis R Koop; M J Coon; Y Takei; Ronald G Thurman
Identification of P-450ALC in microsomes from alcohol dehydrogenase-deficient deermice: contribution to ethanol elimination in vivo.
Archives of biochemistry and biophysics 1988;264(1):114-24.
1988: Donald Forman; Blair U Bradford; J A Handler; E B Glassman; Ronald G Thurman
Involvement of hormones in the swift increase in alcohol metabolism.
Annals of clinical and laboratory science 1988;18(4):318-25.
1988: M E Marotto; Ronald G Thurman; John J Lemasters
Early midzonal cell death during low-flow hypoxia in the isolated, perfused rat liver: protection by allopurinol.
Hepatology (Baltimore, Md.) 1988;8(3):585-90.
1988: J C Caldwell-Kenkel; Ronald G Thurman; John J Lemasters
Selective loss of nonparenchymal cell viability after cold ischemic storage of rat livers.
Transplantation 1988;45(4):834-7.
1988: L B LaCagnin; Henry D Connor; Ronald P Mason; Ronald G Thurman
The carbon dioxide anion radical adduct in the perfused rat liver: relationship to halocarbon-induced toxicity.
Molecular pharmacology 1988;33(3):351-7.
1988: J G Conway; F C Kauffman; T Tsukuda; Ronald G Thurman
Glucuronidation of 7-hydroxycoumarin in periportal and pericentral regions of the lobule in livers from untreated and 3-methylcholanthrene-treated rats.
Molecular pharmacology 1988;33(1):111-9.
1988: Ronald G Thurman; E Apel; M Badr; John J Lemasters
Protection of liver by calcium entry blockers.
Annals of the New York Academy of Sciences 1988;522():757-70.
1988: Ronald G Thurman; John J Lemasters
New micro-optical methods to study metabolism in periportal and pericentral regions of the liver lobule.
Drug metabolism reviews 1988;19(3-4):263-81.
1988: Ronald G Thurman; E D Apel; John J Lemasters
Protective effect of nitrendipine against hypoxic injury in perfused livers from ethanol-treated rats.
Journal of cardiovascular pharmacology 1988;12 Suppl 4():S113-6.
1987: J A Handler; Blair U Bradford; E B Glassman; Donald Forman; Ronald G Thurman
Inhibition of catalase-dependent ethanol metabolism in alcohol dehydrogenase-deficient deermice by fructose.
The Biochemical journal 1987;248(2):415-21.
1987: N W Kleckner; Z Kizaki; Ronald G Thurman
Potential intercellular futile cycling of carbohydrates in diabetes.
The Biochemical journal 1987;246(2):417-23.
1987: J A Handler; Ronald G Thurman
Fatty acids supply H2O2 at high rates for the oxidation of ethanol by catalase.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1987;1():225-9.
1986: J A Handler; Blair U Bradford; E Glassman; J K Ladine; Ronald G Thurman
Catalase-dependent ethanol metabolism in vivo in deermice lacking alcohol dehydrogenase.
Biochemical pharmacology 1986;35(24):4487-92.
1985: S A Belinsky; Blair U Bradford; Donald Forman; E B Glassman; M R Felder; Ronald G Thurman
Hepatotoxicity due to allyl alcohol in deermice depends on alcohol dehydrogenase.
Hepatology (Baltimore, Md.) 1985;5(6):1179-82.
1985: E B Glassman; G A McLaughlin; Donald Forman; M R Felder; Ronald G Thurman
Role of alcohol dehydrogenase in the swift increase in alcohol metabolism (SIAM). Studies with deer mice deficient in alcohol dehydrogenase.
Biochemical pharmacology 1985;34(19):3523-6.
1982: Ronald G Thurman; D Paschal; C Abu-Murad; L Pekkanen; Blair U Bradford; K Bullock; E Glassman
Swift increase in alcohol metabolism (SIAM) in the mouse: comparison of the effect of short-term ethanol treatment on ethanol elimination in four inbred strains.
The Journal of pharmacology and experimental therapeutics 1982;223(1):45-9.
1980: L A Reinke; F C Kauffman; Ronald G Thurman
Stimulation of p-nitroanisole O-demethylation in perfused livers by xylitol and sorbitol.
Biochemical pharmacology 1980;29(5):813-9.
1980: F C Kauffman; R K Evans; L A Reinke; S A Belinsky; C Ballow; Ronald G Thurman
Effects of 3-methylcholanthrene on oxidized nicotinamide-adenine dinucleotide phosphatedependent dehydrogenases and selected metabolites in perfused rat liver.
Biochemical pharmacology 1980;29(5):697-700.