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Thomas Thykjaer

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Fabrice Moore; Najib Naamane; Maikel L Colli; Thomas Bouckenooghe; Fernanda Ortis; Esteban N Gurzov; Mariana Igoillo-Esteve; Chantal Mathieu; Gianluca Bontempi; Thomas Thykjaer; Torben F Ørntoft; Decio L Eizirik
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
S Dad; E Østergaard; Thomas Thykjaer; A Albrectsen; K Ravn; T Rosenberg; L B Møller
Identification of a novel locus for a USH3 like syndrome combined with congenital cataract.
Fernanda Ortis; Najib Naamane; Daisy Flamez; Laurence Ladrière; Fabrice Moore; Daniel Cunha; Maikel L Colli; Thomas Thykjaer; Kasper Thorsen; Torben F Orntoft; Decio L Eizirik
Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.

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All Publications

2011: Fabrice Moore; Najib Naamane; Maikel L Colli; Thomas Bouckenooghe; Fernanda Ortis; Esteban N Gurzov; Mariana Igoillo-Esteve; Chantal Mathieu; Gianluca Bontempi; Thomas Thykjaer; Torben F Ørntoft; Decio L Eizirik
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
The Journal of biological chemistry 2011;286(2):929-41.
2010: S Dad; E Østergaard; Thomas Thykjaer; A Albrectsen; K Ravn; T Rosenberg; L B Møller
Identification of a novel locus for a USH3 like syndrome combined with congenital cataract.
Clinical genetics 2010;78(4):388-97.
2010: Fernanda Ortis; Najib Naamane; Daisy Flamez; Laurence Ladrière; Fabrice Moore; Daniel Cunha; Maikel L Colli; Thomas Thykjaer; Kasper Thorsen; Torben F Orntoft; Decio L Eizirik
Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.
Diabetes 2010;59(2):358-74.
2008: Malene Herbsleb; Karin Birkenkamp-Demtroder; Thomas Thykjaer; Carsten Wiuf; Anne-Mette K Hein; Torben F Orntoft; Lars Dyrskjøt
Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells.
BMC medical genomics 2008;1():31.
2008: Malene Herbsleb; Ole F Christensen; Thomas Thykjaer; Carsten Wiuf; Michael Borre; Torben F Orntoft; Lars Dyrskjøt
Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situ in the urinary bladder.
BMC cancer 2008;8():37.
2007: Mogens Kruhøffer; Lars Dyrskjøt; Thorsten Voss; Raija L P Lindberg; Ralf Wyrich; Thomas Thykjaer; Torben F Orntoft
Isolation of microarray-grade total RNA, microRNA, and DNA from a single PAXgene blood RNA tube.
The Journal of molecular diagnostics : JMD 2007;9(4):452-8.
2006: Ashfaque Memon; Boe Sandahl Sorensen; Peter Meldgaard; Lars Fokdal; Thomas Thykjaer; Ebba Nexo
The relation between survival and expression of HER1 and HER2 depends on the expression of HER3 and HER4: a study in bladder cancer patients.
British journal of cancer 2006;94(11):1703-9.
2006: Mads Aaboe; Karin Birkenkamp-Demtroder; Carsten Wiuf; Flemming Brandt Sørensen; Thomas Thykjaer; Guido Sauter; Klaus Møller-Ernst Jensen; Lars Dyrskjøt; Torben F Ørntoft
SOX4 expression in bladder carcinoma: clinical aspects and in vitro functional characterization.
Cancer research 2006;66(7):3434-42.
2005: Mads Aaboe; Niels Marcussen; Klaus Møller-Ernst Jensen; Thomas Thykjaer; Lars Dyrskjøt; Torben F Orntoft
Gene expression profiling of noninvasive primary urothelial tumours using microarrays.
British journal of cancer 2005;93(10):1182-90.
2005: Tariq Enver; Shamit Soneji; Chirag Joshi; John Brown; Francisco J Iborra; Torben F Orntoft; Thomas Thykjaer; Edna Maltby; Kath Smith; Raed Abu Dawud; Mark Jones; Maryam Matin; paul Gokhale; Jonathan S Draper; Peter W Andrews
Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells.
Human molecular genetics 2005;14(21):3129-40.
2005: Mogens Kruhøffer; Jens Ledet Jensen; Päivi Laiho; Lars Dyrskjøt; Reijo Salovaara; Diego Arango; Karin Birkenkamp-Demtroder; Flemming Brandt Sørensen; Lise Lotte Christensen; L Buhl; Jukka-Pekka Mecklin; Heikki Järvinen; Thomas Thykjaer; Friedrik P Wikman; F Bech-Knudsen; M Juhola; Nina N Nupponen; Søren Laurberg; Claus L Andersen; Lauri A Aaltonen; Torben F Ørntoft
Gene expression signatures for colorectal cancer microsatellite status and HNPCC.
British journal of cancer 2005;92(12):2240-8.
2005: Lars Dyrskjøt; Karsten Zieger; Mogens Kruhøffer; Thomas Thykjaer; Jens Ledet Jensen; Hanne Primdahl; Natasha Aziz; Niels Marcussen; Klaus Møller; Torben F Orntoft
A molecular signature in superficial bladder carcinoma predicts clinical outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(11):4029-36.
2005: Ashfaque Memon; Boe Sandahl Sorensen; Peter Meldgaard; Lars Fokdal; Thomas Thykjaer; Ebba Nexo
Down-regulation of S100C is associated with bladder cancer progression and poor survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):606-11.
2004: Ashfaque Memon; Boe Sandahl Sorensen; P Melgard; Lars Fokdal; Thomas Thykjaer; Ebba Nexo
Expression of HER3, HER4 and their ligand heregulin-4 is associated with better survival in bladder cancer patients.
British journal of cancer 2004;91(12):2034-41.
2004: Jonathan C Cheng; Christine B Yoo; Daniel J Weisenberger; Jody Chuang; Chandra Wozniak; Gangning Liang; Victor E Marquez; Sheldon Greer; Torben F Orntoft; Thomas Thykjaer; Peter A Jones
Preferential response of cancer cells to zebularine.
Cancer cell 2004;6(2):151-8.
2004: Lars Dyrskjøt; Mogens Kruhøffer; Thomas Thykjaer; Niels Marcussen; Jens Ledet Jensen; Klaus Møller; Torben F Ørntoft
Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.
Cancer research 2004;64(11):4040-8.
2003: Lasse Tengbjerg Hansen; Thomas Thykjaer; Torben F Ørntoft; Lene Juel Rasmussen; P Keller; Mogens Spang-Thomsen; Tina Bocker Edmonston; Christoph Schmutte; Richard Fishel; Lone Nørgård Petersen
The role of mismatch repair in small-cell lung cancer cells.
European journal of cancer (Oxford, England : 1990) 2003;39(10):1456-67.
2003: Lars Dyrskjøt; Thomas Thykjaer; Mogens Kruhøffer; Jens Ledet Jensen; Niels Marcussen; Stephen Hamilton-Dutoit; Hans Wolf; Torben F Orntoft
Identifying distinct classes of bladder carcinoma using microarrays.
Nature genetics 2003;33(1):90-6.
2002: Jan Hilpert; Lise Wogensen; Thomas Thykjaer; Maren Wellner; Uwe Schlichting; Torben F Orntoft; Sebastian Bachmann; Anders Nykjaer; Thomas E Willnow
Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism.
Kidney international 2002;62(5):1672-81.
2002: John De Vos; Thomas Thykjaer; Karin Tarte; Matthias Ensslen; Pierre Raynaud; Guilhem Requirand; Florence Pellet; Véronique Pantesco; Thierry Rème; Michel Jourdan; Jean-François Rossi; Torben F Ørntoft; Bernard Klein
Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays.
Oncogene 2002;21(44):6848-57.
2002: Karin Tarte; John De Vos; Thomas Thykjaer; Fenghuang Zhan; Geneviève Fiol; Valérie Costes; Thierry Rème; Eric Legouffe; Jean-François Rossi; John Shaughnessy; Torben F Ørntoft; Bernard Klein
Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts.
Blood 2002;100(4):1113-22.
2002: Gangning Liang; Felicidad A Gonzales; Peter A Jones; Torben F Orntoft; Thomas Thykjaer
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine.
Cancer research 2002;62(4):961-6.
2002: Torben F Ørntoft; Thomas Thykjaer; Frederic M Waldman; Hans Wolf; Julio E Celis
Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas.
Molecular & cellular proteomics : MCP 2002;1(1):37-45.
2001: Mikkel W Pedersen; Thomas Thykjaer; Torben F Ørntoft; Lars Damstrup; Hans Skovgaard Poulsen
Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line.
British journal of cancer 2001;85(8):1211-8.
2001: Thomas Thykjaer; M Christensen; A B Clark; L R Hansen; T A Kunkel; Torben F Ørntoft
Functional analysis of the mismatch repair system in bladder cancer.
British journal of cancer 2001;85(4):568-75.
2001: Andreas Wyttenbach; Jina Swartz; H Kita; Thomas Thykjaer; Jenny Carmichael; J Bradley; Rosemary Brown; M Maxwell; A Schapira; Torben F Orntoft; Kikuya Kato; David C Rubinsztein
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease.
Human molecular genetics 2001;10(17):1829-45.
2001: S H Olesen; Thomas Thykjaer; Torben F Ørntoft
Mitotic checkpoint genes hBUB1, hBUB1B, hBUB3 and TTK in human bladder cancer, screening for mutations and loss of heterozygosity.
Carcinogenesis 2001;22(5):813-5.
2001: Thomas Thykjaer; C Workman; Mogens Kruhøffer; K Demtröder; Hans Wolf; L D Andersen; Casper Frederiksen; S Knudsen; Torben F Orntoft
Identification of gene expression patterns in superficial and invasive human bladder cancer.
Cancer research 2001;61(6):2492-9.
2000: Friedrik P Wikman; M L Lu; Thomas Thykjaer; S H Olesen; L D Andersen; Carlos Cordon-Cardo; Torben F Orntoft
Evaluation of the performance of a p53 sequencing microarray chip using 140 previously sequenced bladder tumor samples.
Clinical chemistry 2000;46(10):1555-61.
2000: Julio E Celis; Mogens Kruhøffer; Irina Gromova; Casper Frederiksen; M Ostergaard; Thomas Thykjaer; Pavel Gromov; J Yu; H Pálsdóttir; Nils E Magnusson; Torben F Orntoft
Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics.
FEBS letters 2000;480(1):2-16.
1998: Leif Schauser; Kurt J Handberg; Niels Sandal; Jiri Stiller; Thomas Thykjaer; Eloisa Pajuelo; A Nielsen; Jens Stougaard
Symbiotic mutants deficient in nodule establishment identified after T-DNA transformation of Lotus japonicus.
Molecular & general genetics : MGG 1998;259(4):414-23.
1997: Thomas Thykjaer; J Finnemann; Leif Schauser; L Christensen; C Poulsen; Jens Stougaard
Gene targeting approaches using positive-negative selection and large flanking regions.
Plant molecular biology 1997;35(4):523-30.
1997: Thomas Thykjaer; D Danielsen; Q She; Jens Stougaard
Organization and expression of genes in the genomic region surrounding the glutamine synthetase gene Gln1 from Lotus japonicus.
Molecular & general genetics : MGG 1997;255(6):628-36.
1995: Thomas Thykjaer; J Stiller; K Handberg; J Jones; Jens Stougaard
The maize transposable element Ac is mobile in the legume Lotus japonicus.
Plant molecular biology 1995;27(5):981-93.