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Kevin Tidgewell

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Marcy J Balunas; Niclas Engene; Lena Gerwick; Manuel F Grosso; Dennis E Kyle; Kerry L McPhail; Laura M Pineda; Carmenza Spadafora; Kevin Tidgewell; Francisco A Villa; William H Gerwick
Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins.
Kenneth Lamb; Denise S Simpson; Kevin Tidgewell; Laura M Bohn; Thomas E Prisinzano
Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology.
Kevin Tidgewell; Niclas Engene; Tara Byrum; Joseph Media; Takayuki Doi; Frederick A Valeriote; William H Gerwick
Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii.

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All Publications

2012: Marcy J Balunas; Niclas Engene; Lena Gerwick; Manuel F Grosso; Dennis E Kyle; Kerry L McPhail; Laura M Pineda; Carmenza Spadafora; Kevin Tidgewell; Francisco A Villa; William H Gerwick
Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins.
Organic letters 2012;14(15):3878-81.
2012: Kenneth Lamb; Denise S Simpson; Kevin Tidgewell; Laura M Bohn; Thomas E Prisinzano
Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology.
Drug and alcohol dependence 2012;121(3):181-8.
2010: Kevin Tidgewell; Niclas Engene; Tara Byrum; Joseph Media; Takayuki Doi; Frederick A Valeriote; William H Gerwick
Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii.
Chembiochem : a European journal of chemical biology 2010;11(10):1458-66.
2010: Marcy J Balunas; Roger G Linington; Kevin Tidgewell; Amanda M Fenner; Luis-David Ureña; Gina Della Togna; Dennis E Kyle; William H Gerwick
Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity.
Journal of natural products 2010;73(1):60-6.
2008: Kevin Tidgewell; Chad E Groer; Wayne W Harding; Anthony Lozama; Matthew Schmidt; Alfred Marquam; Jessica Hiemstra; John S Partilla; Christina M Dersch; Richard B Rothman; Laura M Bohn; Thomas E Prisinzano
Herkinorin analogues with differential beta-arrestin-2 interactions.
Journal of medicinal chemistry 2008;51(8):2421-31.
2007: Kenneth G Holden; Kevin Tidgewell; Alfred Marquam; Richard B Rothman; Hernán Navarro; Thomas E Prisinzano
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: exploration of the 1-position.
Bioorganic & medicinal chemistry letters 2007;17(22):6111-5.
2007: Heng Xu; John S Partilla; Xiaoying Wang; John M Rutherford; Kevin Tidgewell; Thomas E Prisinzano; Laura M Bohn; Richard B Rothman
A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence.
Synapse (New York, N.Y.) 2007;61(3):166-75.
2007: C E Groer; Kevin Tidgewell; R A Moyer; Wayne W Harding; Richard B Rothman; Thomas E Prisinzano; Laura M Bohn
An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.
Molecular pharmacology 2007;71(2):549-57.
2007: Richard B Rothman; Daniel L Murphy; Heng Xu; Jonathan A Godin; Christina M Dersch; John S Partilla; Kevin Tidgewell; Matthew Schmidt; Thomas E Prisinzano
Salvinorin A: allosteric interactions at the mu-opioid receptor.
The Journal of pharmacology and experimental therapeutics 2007;320(2):801-10.
2007: Eduardo R Butelman; Marek Mandau; Kevin Tidgewell; Thomas E Prisinzano; Vadim Yuferov; Mary Jeanne Kreek
Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans.
The Journal of pharmacology and experimental therapeutics 2007;320(1):300-6.
2006: Wayne W Harding; Matthew Schmidt; Kevin Tidgewell; Pavitra Kannan; Kenneth G Holden; Christina M Dersch; Richard B Rothman; Thomas E Prisinzano
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring.
Bioorganic & medicinal chemistry letters 2006;16(12):3170-4.
2006: Kevin Tidgewell; Wayne W Harding; Anthony Lozama; Howard Cobb; Kushal Shah; Pavitra Kannan; Christina M Dersch; Damon Parrish; Jeffrey Deschamps; Richard B Rothman; Thomas E Prisinzano
Synthesis of salvinorin A analogues as opioid receptor probes.
Journal of natural products 2006;69(6):914-8.
2006: Wayne W Harding; Matthew Schmidt; Kevin Tidgewell; Pavitra Kannan; Kenneth G Holden; Brian Gilmour; Hernan Navarro; Richard B Rothman; Thomas E Prisinzano
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: semisynthesis of salvinicins A and B and other chemical transformations of salvinorin A.
Journal of natural products 2006;69(1):107-12.
2005: Matthew D Schmidt; Mark S Schmidt; Eduardo R Butelman; Wayne W Harding; Kevin Tidgewell; Daryl J Murry; Mary Jeanne Kreek; Thomas E Prisinzano
Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates.
Synapse (New York, N.Y.) 2005;58(3):208-10.
2005: Wayne W Harding; Kevin Tidgewell; Nathan Byrd; Howard Cobb; Christina M Dersch; Eduardo R Butelman; Richard B Rothman; Thomas E Prisinzano
Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.
Journal of medicinal chemistry 2005;48(15):4765-71.
2005: Wayne W Harding; Kevin Tidgewell; Matthew Schmidt; Kushal Shah; Christina M Dersch; John Snyder; Damon Parrish; Jeffrey Deschamps; Richard B Rothman; Thomas E Prisinzano
Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum.
Organic letters 2005;7(14):3017-20.
2005: Mark S Schmidt; Thomas E Prisinzano; Kevin Tidgewell; Wayne W Harding; Eduardo R Butelman; Mary Jeanne Kreek; Daryl J Murry
Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;818(2):221-5.
2005: Thomas E Prisinzano; Kevin Tidgewell; Wayne W Harding
Kappa opioids as potential treatments for stimulant dependence.
The AAPS journal 2005;7(3):E592-9.
2004: Kevin Tidgewell; Wayne W Harding; Mark Schmidt; Kenneth G Holden; Daryl J Murry; Thomas E Prisinzano
A facile method for the preparation of deuterium labeled salvinorin A: synthesis of [2,2,2-2H3]-salvinorin A.
Bioorganic & medicinal chemistry letters 2004;14(20):5099-102.