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Gisa Tiegs

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Kristin Thiele; Petra Arck; Annette Erhardt; Timo Kessler; Gisa Tiegs
Acetaminophen and pregnancy: short- and long-term consequences for mother and child.
Antonella Carambia; Christian Frenzel; Oliver T Bruns; Heinz Hohenberg; Samuel Huber; Ansgar W Lohse; Rudolph Reimer; Christoph Schramm; Dorothee Schwinge; Gisa Tiegs; Johannes Herkel
Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells.
Jan-Hendrik Riedel; Rolf A K Stahl; Oliver M Steinmetz; Gisa Tiegs; André P Tittel; Jan-Eric Turner; Joachim Velden; Claudia Wegscheid; Erik Disteldorf; Natalio Garbi; Christian Krebs; Christian Kurts; Hans-Willi Mittrücker; Hans-Joachim Paust; Ulf Panzer
Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN.

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2013: Kristin Thiele; Petra Arck; Annette Erhardt; Timo Kessler; Gisa Tiegs
Acetaminophen and pregnancy: short- and long-term consequences for mother and child.
Journal of reproductive immunology 2013;97(1):128-39.
2013: Antonella Carambia; Christian Frenzel; Oliver T Bruns; Heinz Hohenberg; Samuel Huber; Ansgar W Lohse; Rudolph Reimer; Christoph Schramm; Dorothee Schwinge; Gisa Tiegs; Johannes Herkel
Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells.
Journal of hepatology 2013;58(1):112-8.
2012: Jan-Hendrik Riedel; Rolf A K Stahl; Oliver M Steinmetz; Gisa Tiegs; André P Tittel; Jan-Eric Turner; Joachim Velden; Claudia Wegscheid; Erik Disteldorf; Natalio Garbi; Christian Krebs; Christian Kurts; Hans-Willi Mittrücker; Hans-Joachim Paust; Ulf Panzer
Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN.
Journal of the American Society of Nephrology : JASN 2012;23(12):1987-2000.
2012: Janine Kah; Amelie Dorothea Keller; Roberta Montalbano; Matthias Ocker; Hüseyin Sirma; Gisa Tiegs; Tassilo Volz; Andrea Wüstenberg; Maura Dandri; Gabriele Sass
Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
Oncology reports 2012;28(3):1077-83.
2012: Roja Barikbin; Annette Erhardt; Johannes Kluwe; Daniel Neureiter; Christoph Schramm; Dorothee Schwinge; Gisa Tiegs; Jan Wirth; Gabriele Sass
Induction of heme oxygenase 1 prevents progression of liver fibrosis in Mdr2 knockout mice.
Hepatology (Baltimore, Md.) 2012;55(2):553-62.
2012: Gisa Tiegs
Preface. Inflammation and cancer.
Digestive diseases (Basel, Switzerland) 2012;30(5):443-4.
2012: Sabrina Sieber; Gisa Tiegs; Nicole Lange; Alexander Quaas; Gabriele Sass; Annette Erhardt; Artur Gontarewicz; Gwendlyn Kollmorgen; Hans-Jürgen Kreienkamp
Sharpin contributes to TNFα dependent NFκB activation and anti-apoptotic signalling in hepatocytes.
PloS one 2012;7(1):e29993.
2012: G Sass; R Barikbin; Gisa Tiegs
The multiple functions of heme oxygenase-1 in the liver.
Zeitschrift für Gastroenterologie 2012;50(1):34-40.
2011: Bettina A Mayer; Markus Rehberg; Christoph Reichel; Gisa Tiegs; Angelika M Vollmar; Alexander Wolf; Stefan Zahler; Annette Erhardt; Michael Kracht; Fritz Krombach; Robert Fürst
Inhibitor of apoptosis proteins as novel targets in inflammatory processes.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(10):2240-50.
2011: Gabriele Sass; Hüseyin Sirma; Henning Wege; Said Hashemolhosseini; Claus Hellerbrand; Nina Klinger; Daniel Neureiter; Matthias Ocker; Gisa Tiegs
Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT.
International journal of oncology 2011;39(2):433-42.
2011: Hans-Joachim Paust; Tim D. Sparwasser; Jan-Eric Turner; Joachim Velden; Annette Erhardt; Hans-Willi Mittrücker; Annett Ostmann; Ulf Panzer; Gisa Tiegs
Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis.
Kidney international 2011;80(2):154-64.
2011: Annette Erhardt; Claudia Wegscheid; Benjamin Claass; Antonella Carambia; Johannes Herkel; Hans-Willi Mittrücker; Ulf Panzer; Gisa Tiegs
CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(9):5284-93.
2011: Trayana Kireva; Annette Erhardt; Gisa Tiegs; Herbert Tilg; Helmut Denk; Johannes Haybaeck; Elmar Aigner; Alexander Moschen; Jörg H Distler; Georg Schett; Jochen Zwerina
Transcription factor Fra-1 induces cholangitis and liver fibrosis.
Hepatology (Baltimore, Md.) 2011;53(4):1259-69.
2011: Ulrike K Schmerwitz; Gabriele Sass; Andrej Khandoga; Jos Joore; Bettina A Mayer; Nina Berberich; Frank Totzke; Fritz Krombach; Gisa Tiegs; Stefan Zahler; Angelika M Vollmar; Robert Fürst
Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(2):280-8.
2010: Jan-Eric Turner; Hans-Joachim Paust; Oliver M Steinmetz; Anett Peters; Jan-Hendrik Riedel; Annette Erhardt; Claudia Wegscheid; Joachim Velden; Susanne Fehr; Hans-Willi Mittrücker; Gisa Tiegs; Rolf A K Stahl; Ulf Panzer
CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2010;21(6):974-85.
2010: Elisabeth Lehmann; Walid Hamdy El-Tantawy; Matthias Ocker; Ralf Bartenschlager; Volker Lohmann; Said Hashemolhosseini; Gisa Tiegs; Gabriele Sass
The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response.
Hepatology (Baltimore, Md.) 2010;51(2):398-404.
2010: Markus Biburger; Gabi Theiner; Mirjam Schädle; Gerold Schuler; Gisa Tiegs
Pivotal Advance: Heme oxygenase 1 expression by human CD4+ T cells is not sufficient for their development of immunoregulatory capacity.
Journal of leukocyte biology 2010;87(2):193-202.
2010: Gisa Tiegs; Ansgar W Lohse
Immune tolerance: what is unique about the liver.
Journal of autoimmunity 2010;34(1):1-6.
2010: Annette Erhardt; Gisa Tiegs
Tolerance induction in response to liver inflammation.
Digestive diseases (Basel, Switzerland) 2010;28(1):86-92.
2010: Ansgar W Lohse; Christina Weiler-Normann; Gisa Tiegs
Immune-mediated liver injury.
Journal of hepatology 2010;52(1):136-44.
2009: Mirjam Eberhardt; Lars Neeb; Eva-Maria Vogel; Gisa Tiegs; Uwe Reuter; Karl Messlinger; Michael J M Fischer
Glyceroltrinitrate facilitates stimulated CGRP release but not gene expression of CGRP or its receptor components in rat trigeminal ganglia.
Neuropeptides 2009;43(6):483-9.
2009: F Hoffmann; G Sass; J Zillies; Stefan Zahler; Gisa Tiegs; A Hartkorn; S Fuchs; J Wagner; Gerhard Winter; C Coester; Alexander L Gerbes; Angelika M Vollmar
A novel technique for selective NF-kappaB inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion.
Gut 2009;58(12):1670-8.
2009: Tilmann Ditting; Gisa Tiegs; Kristina Rodionova; Peter W Reeh; Winfried Neuhuber; Wolfgang Freisinger; Roland Veelken
Do distinct populations of dorsal root ganglion neurons account for the sensory peptidergic innervation of the kidney?
American journal of physiology. Renal physiology 2009;297(5):F1427-34.
2009: Tilmann Ditting; Gisa Tiegs; Roland Veelken
Autonomous innervation in renal inflammatory disease-innocent bystander or active modulator?
Journal of molecular medicine (Berlin, Germany) 2009;87(9):865-70.
2009: Irena Kroeger; Annette Erhardt; Dominik Abt; Michael Fischer; Markus Biburger; Thomas Rau; Winfried Neuhuber; Gisa Tiegs
The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice.
Journal of hepatology 2009;51(2):342-53.
2009: Florian Haimerl; Annette Erhardt; Gabriele Sass; Gisa Tiegs
Down-regulation of the de-ubiquitinating enzyme ubiquitin-specific protease 2 contributes to tumor necrosis factor-alpha-induced hepatocyte survival.
The Journal of biological chemistry 2009;284(1):495-504.
2008: Gabriele Sass; Petra Leukel; Volker Schmitz; Esther Raskopf; Matthias Ocker; Daniel Neureiter; Matthias Meissnitzer; Elena Tasika; Andrea Tannapfel; Gisa Tiegs
Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice.
International journal of cancer. Journal international du cancer 2008;123(6):1269-77.
2008: Markus Biburger; Gisa Tiegs
Activation-induced NKT cell hyporesponsiveness protects from alpha-galactosylceramide hepatitis and is independent of active transregulatory factors.
Journal of leukocyte biology 2008;84(1):264-79.
2008: Roland Veelken; Eva-Maria Vogel; K Hilgers; Kerstin Amann; Andrea Hartner; Gabriele Sass; Winfried Neuhuber; Gisa Tiegs
Autonomic renal denervation ameliorates experimental glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2008;19(7):1371-8.
2007: Gabriele Sass; Noula Dattu Shembade; Florian Haimerl; Nicolas Lamoureux; Said Hashemolhosseini; Andrea Tannapfel; Gisa Tiegs
TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):7042-9.
2007: Ulrike Protzer; Stefan Seyfried; Maria Quasdorff; Gabriele Sass; Miriam Svorcova; Dennis Webb; Felix Bohne; Marianna Hösel; Peter Schirmacher; Gisa Tiegs
Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection.
Gastroenterology 2007;133(4):1156-65.
2007: Christoph Schmöcker; Karsten H Weylandt; Lena Kahlke; Jingdong Wang; Hartmut Lobeck; Gisa Tiegs; Thomas Berg; Jing X Kang
Omega-3 fatty acids alleviate chemically induced acute hepatitis by suppression of cytokines.
Hepatology (Baltimore, Md.) 2007;45(4):864-9.
2007: Annette Erhardt; Markus Biburger; Thomas Papadopoulos; Gisa Tiegs
IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice.
Hepatology (Baltimore, Md.) 2007;45(2):475-85.
2007: Gisa Tiegs
Cellular and cytokine-mediated mechanisms of inflammation and its modulation in immune-mediated liver injury.
Zeitschrift für Gastroenterologie 2007;45(1):63-70.
2006: Constance Assohou-Luty; Jeannette Gerspach; Daniela Siegmund; Nicole Müller; Bertrand Huard; Gisa Tiegs; Klaus Pfizenmaier; Harald Wajant
A CD40-CD95L fusion protein interferes with CD40L-induced prosurvival signaling and allows membrane CD40L-restricted activation of CD95.
Journal of molecular medicine (Berlin, Germany) 2006;84(9):785-97.
2005: Matthias Kresse; Markus Latta; Gerald Künstle; Hans-Martin Riehle; Nico van Rooijen; Hannes Hentze; Gisa Tiegs; Markus Biburger; Rudolf Lucas; Albrecht Wendel
Kupffer cell-expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):4076-83.
2005: Signe B Blumenthal; Alexandra K Kiemer; Gisa Tiegs; Stefan Seyfried; Monika Höltje; Birte Brandt; Hans-Dieter Höltje; Stefan Zahler; Angelika M Vollmar
Metalloporphyrins inactivate caspase-3 and -8.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1272-9.
2005: Markus Biburger; Gisa Tiegs
Alpha-galactosylceramide-induced liver injury in mice is mediated by TNF-alpha but independent of Kupffer cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1540-50.
2005: Johannes Herkel; Marcus Schuchmann; Gisa Tiegs; Ansgar W Lohse
Immune-mediated liver injury.
Journal of hepatology 2005;42(6):920-3.
2005: Gabriele Sass; Noula Dattu Shembade; Gisa Tiegs
Tumour necrosis factor alpha (TNF)-TNF receptor 1-inducible cytoprotective proteins in the mouse liver: relevance of suppressors of cytokine signalling.
The Biochemical journal 2005;385(Pt 2):537-44.
2004: Gabriele Sass; Stefan Seyfried; Miguel Parreira Soares; Kenichiro Yamashita; Elzbieta Kaczmarek; Winfried Neuhuber; Gisa Tiegs
Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury.
Hepatology (Baltimore, Md.) 2004;40(5):1128-35.
2004: Winfried Neuhuber; Gisa Tiegs
Innervation of immune cells: evidence for neuroimmunomodulation in the liver.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 2004;280(1):884-92.
2004: Katrin A Mühlen; Jens Schümann; Frederick Wittke; Steffen Stenger; Nico van Rooijen; Luc Van Kaer; Gisa Tiegs
NK cells, but not NKT cells, are involved in Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):3034-41.
2004: Renate Bang; Markus Biburger; Winfried Neuhuber; Gisa Tiegs
Neurokinin-1 receptor antagonists protect mice from CD95- and tumor necrosis factor-alpha-mediated apoptotic liver damage.
The Journal of pharmacology and experimental therapeutics 2004;308(3):1174-80.
2003: Gabriele Sass; Miguel Che Parreira Soares; Kenichiro Yamashita; Stefan Seyfried; Wolfram-Hubertus Zimmermann; Thomas Eschenhagen; Elzbieta Kaczmarek; Thomas Ritter; Hans-Dieter Volk; Gisa Tiegs
Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice.
Hepatology (Baltimore, Md.) 2003;38(4):909-18.
2003: Jens Schümann; Jennifer Prockl; Alexandra K Kiemer; Angelika M Vollmar; Renate Bang; Gisa Tiegs
Silibinin protects mice from T cell-dependent liver injury.
Journal of hepatology 2003;39(3):333-40.
2003: Matthias J T Kaiser; Gisa Tiegs; Winfried Neuhuber
Close apposition of dynorphin-positive nerve fibres to lymphocytes in the liver suggests opioidergic neuroimmunomodulation.
Histochemistry and cell biology 2003;120(3):213-21.
2003: Dierk Samel; Dafne Muller; Jeannette Gerspach; Constance Assohou-Luty; Gabriele Sass; Gisa Tiegs; Klaus Pfizenmaier; Harald Wajant
Generation of a FasL-based proapoptotic fusion protein devoid of systemic toxicity due to cell-surface antigen-restricted Activation.
The Journal of biological chemistry 2003;278(34):32077-82.
2003: Renate Bang; Gabriele Sass; Alexandra K Kiemer; Angelika M Vollmar; Winfried Neuhuber; Gisa Tiegs
Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from cytokine-mediated liver injury.
The Journal of pharmacology and experimental therapeutics 2003;305(1):31-9.
2003: Jens Schümann; Katrin Mühlen; Alexandra K Kiemer; Angelika M Vollmar; Gisa Tiegs
Parenchymal, but not leukocyte, TNF receptor 2 mediates T cell-dependent hepatitis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):2129-37.
2003: Sabine Pullen; Ronald Boecker; Gisa Tiegs
The flame retardants tetrabromobisphenol A and tetrabromobisphenol A-bisallylether suppress the induction of interleukin-2 receptor alpha chain (CD25) in murine splenocytes.
Toxicology 2003;184(1):11-22.
2003: Jie Zhou; Joachim Fandrey; Jens Schümann; Gisa Tiegs; Bernhard Brüne
NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells.
American journal of physiology. Cell physiology 2003;284(2):C439-46.
2002: Dan Tapalaga; Gisa Tiegs; Sabine Angermüller
NFkappaB and caspase-3 activity in apoptotic hepatocytes of galactosamine-sensitized mice treated with TNFalpha.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(12):1599-609.
2002: Kerstin Koerber; Gabriele Sass; Alexandra K Kiemer; Angelika M Vollmar; Gisa Tiegs
In vivo regulation of inducible no synthase in immune-mediated liver injury in mice.
Hepatology (Baltimore, Md.) 2002;36(5):1061-9.
2002: Andrea Thiele; Renate Bang; Michael Gütschow; Manuela Rossol; Sebastian Loos; Kurt Eger; Gisa Tiegs; Sunna Hauschildt
Cytokine modulation and suppression of liver injury by a novel analogue of thalidomide.
European journal of pharmacology 2002;453(2-3):325-34.
2002: Gabriele Sass; Sonja Heinlein; Andrea Agli; Renate Bang; Jens Schümann; Gisa Tiegs
Cytokine expression in three mouse models of experimental hepatitis.
Cytokine 2002;19(3):115-20.
2002: Gabriele Sass; Kerstin Koerber; Gisa Tiegs
TNF tolerance and cytotoxicity in the liver: the role of interleukin-1beta, inducible nitric oxide-synthase and heme oxygenase-1 in D-galactosamine-sensitized mice.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2002;51(5):229-35.
2001: Antje Willuweit; Gabriele Sass; A Schöneberg; Ulrich Eisel; Gisa Tiegs; Matthias Clauss
Chronic inflammation and protection from acute hepatitis in transgenic mice expressing TNF in endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3944-52.
2001: D Wolf; Jens Schümann; Kerstin Koerber; Alexandra K Kiemer; Angelika M Vollmar; Gabriele Sass; Thomas Papadopoulos; Renate Bang; S D Klein; Bernhard Brüne; Gisa Tiegs
Low-molecular-weight hyaluronic acid induces nuclear factor-kappaB-dependent resistance against tumor necrosis factor alpha-mediated liver injury in mice.
Hepatology (Baltimore, Md.) 2001;34(3):535-47.
2001: Konrad L Streetz; B Fregien; Jörg Plümpe; K Körber; Stefan Kubicka; Gabriele Sass; Stephan C Bischoff; Michael P Manns; Gisa Tiegs; Christian Trautwein
Dissection of the intracellular pathways in hepatocytes suggests a role for Jun kinase and IFN regulatory factor-1 in Con A-induced liver failure.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):514-23.
2001: Gabriele Sass; Kerstin Koerber; Renate Bang; H Guehring; Gisa Tiegs
Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice.
The Journal of clinical investigation 2001;107(4):439-47.
2001: D Wolf; Rupert Hallmann; Gabriele Sass; Michael Sixt; Sabine Küsters; B Fregien; Christian Trautwein; Gisa Tiegs
TNF-alpha-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):1300-7.
2000: Jens Schümann; D Wolf; A Pahl; K Brune; Thomas Papadopoulos; Nico van Rooijen; Gisa Tiegs
Importance of Kupffer cells for T-cell-dependent liver injury in mice.
The American journal of pathology 2000;157(5):1671-83.
2000: Jens Schümann; Horst Bluethmann; Gisa Tiegs
Synergism of Pseudomonas aeruginosa exotoxin A with endotoxin, superantigen, or TNF results in TNFR1- and TNFR2-dependent liver toxicity in mice.
Immunology letters 2000;74(2):165-72.
1999: Jens Schümann; Gisa Tiegs
Pathophysiological mechanisms of TNF during intoxication with natural or man-made toxins.
Toxicology 1999;138(2):103-26.
1999: Gerald Künstle; Hannes Hentze; paul germann; Gisa Tiegs; Thomas Meergans; Albrecht Wendel
Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation.
Hepatology (Baltimore, Md.) 1999;30(5):1241-51.
1999: Gisa Tiegs; Renate Bang; Winfried Neuhuber
Requirement of peptidergic sensory innervation for disease activity in murine models of immune hepatitis and protection by beta-adrenergic stimulation.
Journal of neuroimmunology 1999;96(2):131-43.
1999: Sabine Angermüller; Jens Schümann; H Dariush Fahimi; Gisa Tiegs
Ultrastructural alterations of mitochondria in pre-apoptotic and apoptotic hepatocytes of TNF alpha-treated galactosamine-sensitized mice.
Annals of the New York Academy of Sciences 1999;887():12-7.
1998: Gisa Tiegs; Sabine Küsters; Gerald Künstle; Hannes Hentze; Alexandra K Kiemer; Albrecht Wendel
Ebselen protects mice against T cell-dependent, TNF-mediated apoptotic liver injury.
The Journal of pharmacology and experimental therapeutics 1998;287(3):1098-104.
1998: Jens Schümann; Sabine Angermüller; Renate Bang; Michael Lohoff; Gisa Tiegs
Acute hepatotoxicity of Pseudomonas aeruginosa exotoxin A in mice depends on T cells and TNF.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5745-54.
1998: Sabine Angermüller; Gerald Künstle; Gisa Tiegs
Pre-apoptotic alterations in hepatocytes of TNFalpha-treated galactosamine-sensitized mice.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(10):1175-83.
1998: A Lührmann; J Thölke; I Behn; J Schumann; Gisa Tiegs; Sunna Hauschildt
Immunomodulating properties of the antibiotic novobiocin in human monocytes.
Antimicrobial agents and chemotherapy 1998;42(8):1911-6.
1998: Christian Trautwein; T Rakemann; Nisar P Malek; Jörg Plümpe; Gisa Tiegs; Michael P Manns
Concanavalin A-induced liver injury triggers hepatocyte proliferation.
The Journal of clinical investigation 1998;101(9):1960-9.
1998: Christian Trautwein; T Rakemann; David A Brenner; Konrad L Streetz; L Licato; Michael P Manns; Gisa Tiegs
Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice.
Gastroenterology 1998;114(5):1035-45.
1998: M Weisser; Gisa Tiegs; A Wendel; Stefan Uhlig
Quantification of apoptotic and lytic cell death by video microscopy in combination with artificial neural networks.
Cytometry 1998;31(1):20-8.
1997: Sabine Küsters; Gisa Tiegs; Lena Alexopoulou; Manolis Pasparakis; Eleni Douni; Gerald Künstle; Horst Bluethmann; Albrecht Wendel; Klaus Pfizenmaier; george kollias; Matthias Grell
In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis.
European journal of immunology 1997;27(11):2870-5.
1997: Albrecht Wendel; S Kuesters; Gisa Tiegs
Ebselen--an in vivo immune response modifier.
Biomedical and environmental sciences : BES 1997;10(2-3):253-9.
1997: Gisa Tiegs
Experimental hepatitis and role of cytokines.
Acta gastro-enterologica Belgica 1997;60(2):176-9.
1997: Florian Gantner; Sabine Küsters; Albrecht Wendel; Armin Hatzelmann; Christian Schudt; Gisa Tiegs
Protection from T cell-mediated murine liver failure by phosphodiesterase inhibitors.
The Journal of pharmacology and experimental therapeutics 1997;280(1):53-60.
1996: Florian Gantner; Marcel Leist; Sabine Küsters; K Vogt; H D Volk; Gisa Tiegs
T cell stimulus-induced crosstalk between lymphocytes and liver macrophages results in augmented cytokine release.
Experimental cell research 1996;229(1):137-46.
1996: I Bohlinger; Marcel Leist; Florian Gantner; Sabine Angermüller; Gisa Tiegs; Albrecht Wendel
DNA fragmentation in mouse organs during endotoxic shock.
The American journal of pathology 1996;149(4):1381-93.
1996: Percy A Knolle; Guido Gerken; E Loser; Hans P Dienes; Florian Gantner; Gisa Tiegs; K H Meyer zum Buschenfelde; Ansgar W Lohse
Role of sinusoidal endothelial cells of the liver in concanavalin A-induced hepatic injury in mice.
Hepatology (Baltimore, Md.) 1996;24(4):824-9.
1996: Sabine Küsters; Florian Gantner; Gerald Künstle; Gisa Tiegs
Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A.
Gastroenterology 1996;111(2):462-71.
1996: Gisa Tiegs; Florian Gantner
Immunotoxicology of T cell-dependent experimental liver injury.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1996;48(5):471-6.
1996: Marcel Leist; Florian Gantner; Gerald Künstle; I Bohlinger; Gisa Tiegs; Horst Bluethmann; Albrecht Wendel
The 55-kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure.
Molecular medicine (Cambridge, Mass.) 1996;2(1):109-24.
1995: I Bohlinger; Marcel Leist; J Barsig; Stefan Uhlig; Gisa Tiegs; Albrecht Wendel
Tolerance against tumor necrosis factor alpha (TNF)-induced hepatotoxicity in mice: the role of nitric oxide.
Toxicology letters 1995;82-83():227-31.
1995: I Bohlinger; Marcel Leist; J Barsig; Stefan Uhlig; Gisa Tiegs; Albrecht Wendel
Interleukin-1 and nitric oxide protect against tumor necrosis factor alpha-induced liver injury through distinct pathways.
Hepatology (Baltimore, Md.) 1995;22(6):1829-37.
1995: J Barsig; Sabine Küsters; K Vogt; Hans-Dieter Volk; Gisa Tiegs; Albrecht Wendel
Lipopolysaccharide-induced interleukin-10 in mice: role of endogenous tumor necrosis factor-alpha.
European journal of immunology 1995;25(10):2888-93.
1995: Florian Gantner; Marcel Leist; S Jilg; paul germann; M A Freudenberg; Gisa Tiegs
Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice.
Gastroenterology 1995;109(1):166-76.
1995: Marcel Leist; Florian Gantner; I Bohlinger; Gisa Tiegs; paul germann; Albrecht Wendel
Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models.
The American journal of pathology 1995;146(5):1220-34.
1995: Florian Gantner; Marcel Leist; Ansgar W Lohse; paul germann; Gisa Tiegs
Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor.
Hepatology (Baltimore, Md.) 1995;21(1):190-8.
1994: Gisa Tiegs
Immunotoxicology of host-response-mediated experimental liver injury.
Journal of hepatology 1994;21(5):890-903.
1994: Marcel Leist; Florian Gantner; I Bohlinger; paul germann; Gisa Tiegs; Albrecht Wendel
Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(4):1778-88.
1994: Gisa Tiegs; J Barsig; B Matiba; Stefan Uhlig; Albrecht Wendel
Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice.
The Journal of clinical investigation 1994;93(6):2616-22.
1994: Stefanie Dimmeler; U K Messmer; Gisa Tiegs; Bernhard Brüne
Modulation of glyceraldehyde-3-phosphate dehydrogenase in Salmonella abortus equi lipopolysaccharide-treated mice.
European journal of pharmacology 1994;267(1):105-12.
1992: I Görgen; Thomas Hartung; Marcel Leist; M Niehörster; Gisa Tiegs; Stefan Uhlig; F Weitzel; Albrecht Wendel
Granulocyte colony-stimulating factor treatment protects rodents against lipopolysaccharide-induced toxicity via suppression of systemic tumor necrosis factor-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(3):918-24.
1992: Gisa Tiegs; J Hentschel; Albrecht Wendel
A T cell-dependent experimental liver injury in mice inducible by concanavalin A.
The Journal of clinical investigation 1992;90(1):196-203.
1992: Gisa Tiegs; M A Freudenberg; C Galanos; Albrecht Wendel
Colchicine prevents tumor necrosis factor-induced toxicity in vivo.
Infection and immunity 1992;60(5):1941-5.
1992: Thomas Hartung; Gisa Tiegs; Albrecht Wendel
The role of leukotriene D4 in septic shock models.
Eicosanoids 1992;5 Suppl():S42-4.
1990: M Niehörster; Gisa Tiegs; U F Schade; Albrecht Wendel
In vivo evidence for protease-catalysed mechanism providing bioactive tumor necrosis factor alpha.
Biochemical pharmacology 1990;40(7):1601-3.
1990: Gisa Tiegs; M Niehörster; Albrecht Wendel
Leukocyte alterations do not account for hepatitis induced by endotoxin or TNF alpha in galactosamine-sensitized mice.
Biochemical pharmacology 1990;40(6):1317-22.
1989: Gisa Tiegs; M Wolter; Albrecht Wendel
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice.
Biochemical pharmacology 1989;38(4):627-31.
1988: Gisa Tiegs; Albrecht Wendel
Leukotriene-mediated liver injury.
Biochemical pharmacology 1988;37(13):2569-73.