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Pentti Tienari

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Mia Kero; Liisa Myllykangas; Anders Paetau; Tuomo Polvikoski; Raimo Sulkava; Maarit Tanskanen; Lilja Jansson; Pentti J Tienari
Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population.
Kari-Pekka Saastamoinen; Marja-Kaisa Auvinen; Pentti J Tienari
Month of birth is associated with multiple sclerosis but not with HLA-DR15 in Finland.
Kin Mok; Gabriele Mora; Huw R Morris; Karen E Morrison; Liisa Myllykangas; Michael A Nalls; Richard W Orrell; Terhi Peuralinna; Stuart Pickering-Brown; Rosa Rademakers; Gabriella Restagno; Pamela Sara Rollinson; Jennifer C Schymick; Aleksey Shatunov; Pamela J Shaw; Javier Simón-Sánchez; Pentti J Tienari; Bryan Joseph Traynor; John C van Swieten; Adrian Waite; Nigel Williams; Ammar Al-Chalabi; Bradley F Boeve; Adam L Boxer; Adriano Chio; Mariely DeJesus-Hernandez; Peter Heutink; Hannu Laaksovirta; Ian R Mackenzie; John Hardy
Chromosome 9 ALS and FTD locus is probably derived from a single founder.

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All Publications

2013: Mia Kero; Liisa Myllykangas; Anders Paetau; Tuomo Polvikoski; Raimo Sulkava; Maarit Tanskanen; Lilja Jansson; Pentti J Tienari
Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population.
Neurobiology of aging 2013;34(5):1518.e1-3.
2012: Kari-Pekka Saastamoinen; Marja-Kaisa Auvinen; Pentti J Tienari
Month of birth is associated with multiple sclerosis but not with HLA-DR15 in Finland.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(5):563-8.
2012: Kin Mok; Gabriele Mora; Huw R Morris; Karen E Morrison; Liisa Myllykangas; Michael A Nalls; Richard W Orrell; Terhi Peuralinna; Stuart Pickering-Brown; Rosa Rademakers; Gabriella Restagno; Pamela Sara Rollinson; Jennifer C Schymick; Aleksey Shatunov; Pamela J Shaw; Javier Simón-Sánchez; Pentti J Tienari; Bryan Joseph Traynor; John C van Swieten; Adrian Waite; Nigel Williams; Ammar Al-Chalabi; Bradley F Boeve; Adam L Boxer; Adriano Chio; Mariely DeJesus-Hernandez; Peter Heutink; Hannu Laaksovirta; Ian R Mackenzie; John Hardy
Chromosome 9 ALS and FTD locus is probably derived from a single founder.
Neurobiology of aging 2012;33(1):209.e3-8.
2011: Terhi Peuralinna; Tuomo Polvikoski; Andrew Singleton; Raimo Sulkava; Maarit Tanskanen; Pentti J Tienari; Bryan Joseph Traynor; Sampath Arepalli; John Hardy; Dena Hernandez; Hannu Kalimo; Shiao-Lin Lai; Mira Mäkelä; Anders Paetau; Liisa Myllykangas
APOE and AβPP gene variation in cortical and cerebrovascular amyloid-β pathology and Alzheimer's disease: a population-based analysis.
Journal of Alzheimer's disease : JAD 2011;26(2):377-85.
2010: Johanna Eerola; Laura Kananen; Kaisa Manninen; Olli Hellström; Pentti J Tienari; Iiris Hovatta
No evidence for shorter leukocyte telomere length in Parkinson's disease patients.
The journals of gerontology. Series A, Biological sciences and medical sciences 2010;65(11):1181-4.
2010: Hannu Laaksovirta; Terhi Peuralinna; Jennifer C Schymick; Sonja Scholz; Shiao-Lin Lai; Liisa Myllykangas; Raimo Sulkava; Lilja Jansson; Dena G Hernandez; J Raphael Gibbs; Michael A Nalls; David Heckerman; Pentti J Tienari; Bryan Joseph Traynor
Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.
Lancet neurology 2010;9(10):978-85.
2010: Johanna Eerola; Petri Luoma; Terhi Peuralinna; Sonja Scholz; Coro Paisan-Ruiz; Anu Suomalainen; Andrew Singleton; Pentti J Tienari
POLG1 polyglutamine tract variants associated with Parkinson's disease.
Neuroscience letters 2010;477(1):1-5.
2010: Barbara C van Munster; Sophia de Rooij; Mojgan Yazdanpanah; Pentti J Tienari; Kaisu H Pitkälä; Robert J Osse; Dimitrios Adamis; Orla Smit; Marijke S van der Steen; Miriam van Houten; Terhi Rahkonen; Raimo Sulkava; Jouko V Laurila; Timo E Strandberg; Joke H M Tulen; Louwerens Zwang; Alastair J D Macdonald; Adrian Treloar; Eric J G Sijbrands; Aeilko H Zwinderman; Johanna C Korevaar
The association of the dopamine transporter gene and the dopamine receptor 2 gene with delirium, a meta-analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(2):648-55.
2010: J Ockinger; P Stridh; A D Beyeen; F Lundmark; Maria Seddighzadeh; A Oturai; P S Sørensen; A R Lorentzen; E G Celius; V Leppä; Keijo Koivisto; Pentti J Tienari; Lars Alfredsson; Leonid Padyukov; Jan Hillert; Ingrid Kockum; Maja Jagodic; Tomas Olsson
Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis.
Genes and immunity 2010;11(2):142-54.
2010: Eveliina Jakkula; Virpi Leppä; Anna-Maija Sulonen; Teppo Varilo; Suvi Kallio; Anu Kemppinen; Shaun Purcell; Keijo Koivisto; Pentti J Tienari; Marja-Liisa Sumelahti; Irina Elovaara; Tuula Pirttilä; Mauri Reunanen; Arpo Aromaa; Annette Bang Oturai; Helle Bach Søndergaard; Hanne F Harbo; Inger-Lise Mero; Stacey B Gabriel; Daniel B Mirel; Stephen L Hauser; Ludwig Kappos; Chris Polman; Philip L De Jager; David A Hafler; Mark J Daly; Aarno Palotie; Janna Saarela; Leena Peltonen
Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.
American journal of human genetics 2010;86(2):285-91.
2010: P Isohanni; Tarja Linnankivi; J Buzkova; Tuula Lönnqvist; Helena Pihko; Leena Valanne; Pentti J Tienari; I Elovaara; T Pirttilä; M Reunanen; K Koivisto; S Marjavaara; Anu Suomalainen
DARS2 mutations in mitochondrial leucoencephalopathy and multiple sclerosis.
Journal of medical genetics 2010;47(1):66-70.
2009: Anu Kemppinen; Minna Suvela; Pentti J Tienari; Irina Elovaara; Keijo Koivisto; Tuula Pirttilä; Mauri Reunanen; Ilkka Rautakorpi; Jan Hillert; Frida Lundmark; Annette Oturai; Lars Ryder; Hanne F Harbo; Elisabeth G Celius; Aarno Palotie; Mark J Daly; Leena Peltonen; Janna Saarela
MYO9B polymorphisms in multiple sclerosis.
European journal of human genetics : EJHG 2009;17(6):840-3.
2009: Suvi P Kallio; Eveliina Jakkula; Shaun Purcell; Minna Suvela; Keijo Koivisto; Pentti J Tienari; Irina Elovaara; Tuula Pirttilä; Mauri Reunanen; Denis Bronnikov; Markku Viander; Seppo Meri; Jan Hillert; Frida Lundmark; Hanne F Harbo; Aslaug R Lorentzen; Philip L De Jager; Mark J Daly; David A Hafler; Aarno Palotie; Leena Peltonen; Janna Saarela
Use of a genetic isolate to identify rare disease variants: C7 on 5p associated with MS.
Human molecular genetics 2009;18(9):1670-83.
2009: Alessandro Bonetti; Keijo Koivisto; Tuula Pirttilä; Irina Elovaara; Mauri Reunanen; Mikko Laaksonen; Juhani Ruutiainen; Leena Peltonen; Terhi Rantamäki; Pentti J Tienari
A follow-up study of chromosome 19q13 in multiple sclerosis susceptibility.
Journal of neuroimmunology 2009;208(1-2):119-24.
2009: Juho Uusvaara; Kaisu H Pitkala; Pentti J Tienari; Hannu Kautiainen; Reijo S Tilvis; Timo E Strandberg
Association between anticholinergic drugs and apolipoprotein E epsilon4 allele and poorer cognitive function in older cardiovascular patients: a cross-sectional study.
Journal of the American Geriatrics Society 2009;57(3):427-31.
2009: Anna-Maija Sulonen; Suvi P Kallio; Pekka Ellonen; Minna Suvela; Irina Elovaara; Keijo Koivisto; Tuula Pirttilä; Mauri Reunanen; Pentti J Tienari; Aarno Palotie; Leena Peltonen; Janna Saarela
No evidence for shared etiology in two demyelinative disorders, MS and PLOSL.
Journal of neuroimmunology 2009;206(1-2):86-90.
2008: Leena E Viiri; Keijo M Viiri; Erkki Ilveskoski; Heini Huhtala; Markku Mäki; Pentti J Tienari; Markus Perola; Terho Lehtimäki; Pekka J Karhunen
Interactions of functional apolipoprotein E gene promoter polymorphisms with smoking on aortic atherosclerosis.
Circulation. Cardiovascular genetics 2008;1(2):107-16.
2008: Timo E Strandberg; Kaisu H Pitkala; Pentti J Tienari; Reijo S Tilvis
Re: Education and dementia: what lies behind the association?
Neurology 2008;71(19):1555-6; author reply 1556.
2008: Terhi Peuralinna; M Oinas; Tuomo Polvikoski; Anders Paetau; Raimo Sulkava; Leena Niinistö; Hannu Kalimo; Dena Hernandez; John Hardy; Andrew Singleton; Pentti J Tienari; Liisa Myllykangas
Neurofibrillary tau pathology modulated by genetic variation of alpha-synuclein.
Annals of neurology 2008;64(3):348-52.
2008: Aki S Havulinna; Pentti J Tienari; Reijo J Marttila; Kirsti K Martikainen; Johan G Eriksson; Olli Taskinen; Elena Moltchanova; Marjatta Karvonen
Geographical variation of medicated parkinsonism in Finland during 1995 to 2000.
Movement disorders : official journal of the Movement Disorder Society 2008;23(7):1024-31.
2008: Maarit Tanskanen; Terhi Peuralinna; Tuomo Polvikoski; Irma-Leena Notkola; Raimo Sulkava; John Hardy; Andrew Singleton; Sari Kiuru-Enari; Anders Paetau; Pentti J Tienari; Liisa Myllykangas
Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study.
Annals of medicine 2008;40(3):232-9.
2007: Petri Luoma; Johanna Eerola; Sofia Ahola; Anna H Hakonen; Olli Hellström; K T Kivistö; Pentti J Tienari; Anu Suomalainen
Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease.
Neurology 2007;69(11):1152-9.
2007: A Dostal; Tarja Linnankivi; Mirja Somer; M Kähkönen; J Litzman; Pentti J Tienari
Mapping susceptibility gene locus for IgA deficiency at del(18)(q22.3-q23); report of familial cryptic chromosome t(18q; 10p) translocations.
International journal of immunogenetics 2007;34(3):143-7.
2007: Georgia Xiromerisiou; Georgios M Hadjigeorgiou; Johanna Eerola; Hubert H Fernandez; V Tsimourtou; R Mandel; Olli Hellström; Katrina Gwinn-Hardy; Michael S Okun; Pentti J Tienari; Andrew Singleton
BDNF tagging polymorphisms and haplotype analysis in sporadic Parkinson's disease in diverse ethnic groups.
Neuroscience letters 2007;415(1):59-63.
2006: Anna Rautanen; Johan G Eriksson; Juha Kere; Sture Andersson; Clive Osmond; Pentti J Tienari; Heikki Sairanen; David J P Barker; David I W Phillips; Tom Forsén; Eero Kajantie
Associations of body size at birth with late-life cortisol concentrations and glucose tolerance are modified by haplotypes of the glucocorticoid receptor gene.
The Journal of clinical endocrinology and metabolism 2006;91(11):4544-51.
2006: Maarit Tanskanen; Sari Kiuru-Enari; Pentti J Tienari; Tuomo Polvikoski; Auli Verkkoniemi; Sari Rastas; Raimo Sulkava; Anders Paetau
Senile systemic amyloidosis, cerebral amyloid angiopathy, and dementia in a very old Finnish population.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2006;13(3):164-9.
2006: Jordi Clarimon; Sonja Scholz; Hon-Chung Fung; John Hardy; Johanna Eerola; Olli Hellstrom; Chiung-Mei Chen; Yih-Ru Wu; Pentti J Tienari; Andrew Singleton
Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease.
American journal of human genetics 2006;78(6):1082-4; author reply 1092-4.
2006: Jordi Clarimón; Johanna Eerola; Olli Hellström; Terhi Peuralinna; Pentti J Tienari; Andrew Singleton
Assessment of PINK1 (PARK6) polymorphisms in Finnish PD.
Neurobiology of aging 2006;27(6):906-7.
2006: Sonja Scholz; Georgia Xiromerisiou; Hon-Chung Fung; Johanna Eerola; Olli Hellström; Alexandros Papadimitriou; Georgios M Hadjigeorgiou; Pentti J Tienari; Hubert H Fernandez; Ronald Mandel; Michael S Okun; Katrina Gwinn-Hardy; Andrew Singleton
The human prion gene M129V polymorphism is not associated with idiopathic Parkinson's disease in three distinct populations.
Neuroscience letters 2006;395(3):227-9.
2006: Janna Saarela; Suvi P Kallio; Daniel Chen; Alexandre Montpetit; Anne Jokiaho; Eva Choi; Rosanna Asselta; Denis Bronnikov; Matthew R Lincoln; A Dessa Sadovnick; Pentti J Tienari; Keijo Koivisto; Aarno Palotie; George C Ebers; Thomas J Hudson; Leena Peltonen
PRKCA and multiple sclerosis: association in two independent populations.
PLoS genetics 2006;2(3):e42.
2006: Pentti J Tienari; Alessandro Bonetti; Hannele Pihlaja; Kari-Pekka Saastamoinen; Terhi Rantamäki
Multiple sclerosis in G: genes and geography.
Clinical neurology and neurosurgery 2006;108(3):223-6.
2006: Tarja Linnankivi; Pentti J Tienari; Mirja Somer; Marketta Kähkönen; Tuula Lönnqvist; Leena Valanne; Helena Pihko
18q deletions: clinical, molecular, and brain MRI findings of 14 individuals.
American journal of medical genetics. Part A 2006;140(4):331-9.
2006: Hon-Chung Fung; Georgia Xiromerisiou; J Raphael Gibbs; Y R Wu; Johanna Eerola; Vanessa Gourbali; Olli Hellström; C M Chen; Jaime Duckworth; Alexandros Papadimitriou; Pentti J Tienari; Georgios M Hadjigeorgiou; John Hardy; Andrew Singleton
Association of tau haplotype-tagging polymorphisms with Parkinson's disease in diverse ethnic Parkinson's disease cohorts.
Neuro-degenerative diseases 2006;3(6):327-33.
2005: H M F Riise Stensland; Janna Saarela; Denis O Bronnikov; Maija Parkkonen; Anne Jokiaho; Aarno Palotie; Pentti J Tienari; Marja-Liisa Sumelahti; Irina Elovaara; Keijo Koivisto; Tuula Pirttilä; Mauri Reunanen; Eric Sobel; Leena Peltonen
Fine mapping of the multiple sclerosis susceptibility locus on 5p14-p12.
Journal of neuroimmunology 2005;170(1-2):122-33.
2005: Maarit Tanskanen; Perttu J Lindsberg; Pentti J Tienari; Tuomo Polvikoski; Raimo Sulkava; Auli Verkkoniemi; Sari Rastas; Anders Paetau; Sari Kiuru-Enari
Cerebral amyloid angiopathy in a 95+ cohort: complement activation and apolipoprotein E (ApoE) genotype.
Neuropathology and applied neurobiology 2005;31(6):589-99.
2005: Matthew R Lincoln; Alexandre Montpetit; zameel cader; Janna Saarela; David A Dyment; Milvi Tiislar; Vincent Ferretti; Pentti J Tienari; A Dessa Sadovnick; Leena Peltonen; George C Ebers; Thomas J Hudson
A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.
Nature genetics 2005;37(10):1108-12.
2005: Liisa Myllykangas; Fabienne Wavrant-De Vrièze; Tuomo Polvikoski; Irma-Leena Notkola; Raimo Sulkava; Leena Niinistö; Steven D Edland; Sampath Arepalli; Omanma Adighibe; Danielle Compton; John Hardy; Matti Haltia; Pentti J Tienari
Chromosome 21 BACE2 haplotype associates with Alzheimer's disease: a two-stage study.
Journal of the neurological sciences 2005;236(1-2):17-24.
2005: Johanna Eerola; Pentti J Tienari; S Kaakkola; Paivi Nikkinen; Jyrki Launes
How useful is [123I]beta-CIT SPECT in clinical practice?
Journal of neurology, neurosurgery, and psychiatry 2005;76(9):1211-6.
2005: Timo E Strandberg; Kaisu H Pitkala; Johanna Eerola; Reijo S Tilvis; Pentti J Tienari
Interaction of herpesviridae, APOE gene, and education in cognitive impairment.
Neurobiology of aging 2005;26(7):1001-4.
2005: Elisa Greggio; Elisabetta Bergantino; Donald Carter; Rili Ahmad; Gertrude-E Costin; Vincent J Hearing; Jordi Clarimon; Andrew Singleton; Johanna Eerola; Olli Hellström; Pentti J Tienari; David W Miller; Alexandra Beilina; Luigi Bubacco; Mark Cookson
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease.
Journal of neurochemistry 2005;93(1):246-56.
2005: Jordi Clarimon; Georgia Xiromerisiou; Johanna Eerola; Vanessa Gourbali; Olli Hellström; Euthimios Dardiotis; Terhi Peuralinna; Alexandros Papadimitriou; Georgios M Hadjigeorgiou; Pentti J Tienari; Andrew Singleton
Lack of evidence for a genetic association between FGF20 and Parkinson's disease in Finnish and Greek patients.
BMC neurology 2005;5():11.
2005: Silvia Buervenich; Andrea Carmine; Dagmar Galter; Haydeh N Shahabi; Bo Johnels; Björn Holmberg; Jarl Ahlberg; Hans Nissbrandt; Johanna Eerola; Olli Hellström; Pentti J Tienari; Tohru Matsuura; Tetsuo Ashizawa; Ullrich Wüllner; Thomas Klockgether; Alexander Zimprich; Thomas Gasser; Melissa Hanson; Shamaila Waseem; Andrew Singleton; Francis McMajon; Maria Anvret; Olof Sydow; Lars Olson
A rare truncating mutation in ADH1C (G78Stop) shows significant association with Parkinson disease in a large international sample.
Archives of neurology 2005;62(1):74-8.
2004: Whitney Evans; Hon-Chung Fung; John Steele; Johanna Eerola; Pentti J Tienari; Alan Pittman; Rohan de Silva; Amanda Myers; Fabienne Wavrant-De Vrieze; Andrew Singleton; John Hardy
The tau H2 haplotype is almost exclusively Caucasian in origin.
Neuroscience letters 2004;369(3):183-5.
2004: Jordi Clarimon; Johanna Eerola; Olli Hellström; Pentti J Tienari; Andrew Singleton
Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population.
Neuroscience letters 2004;367(2):168-70.
2004: Janel Johnson; Stephen Hague; Melissa Hanson; A Gibson; K E Wilson; E Whitney Evans; Amanda Adam Singleton; Aideen McInerney-Leo; Robert L Nussbaum; Dena G Hernandez; Marisol Gallardo; Ian G McKeith; David J Burn; M Ryu; O Hellstrom; Bernard Ravina; Johanna Eerola; Robert H Perry; E Jaros; Pentti J Tienari; Roberto Weiser; Katrina Gwinn-Hardy; Christopher M Morris; John Hardy; Andrew Singleton
SNCA multiplication is not a common cause of Parkinson disease or dementia with Lewy bodies.
Neurology 2004;63(3):554-6.
2004: Pentti J Tienari; Marja-Liisa Sumelahti; Terhi Rantamäki; Juhani Wikström
Multiple sclerosis in western Finland: evidence for a founder effect.
Clinical neurology and neurosurgery 2004;106(3):175-9.
2004: A Bonetti; Karoliina Reunanen; Saara Finnilä; Keijo Koivisto; Juhani Wikström; Marja-Liisa Sumelahti; T Pirttilä; Irina Elovaara; Mauri Reunanen; Janna Saarela; Leena Peltonen; Terhi Rantamäki; Pentti J Tienari
A two-stage study on multiple sclerosis susceptibility and chromosome 2q33.
Genes and immunity 2004;5(2):142-6.
2004: Stephen Hague; Terhi Peuralinna; Johanna Eerola; Olli Hellström; Pentti J Tienari; Andrew Singleton
Confirmation of the protective effect of iNOS in an independent cohort of Parkinson disease.
Neurology 2004;62(4):635-6.
2003: Johanna Eerola; D Hernandez; Jyrki Launes; Olli Hellström; Stephen Hague; Cindy Gulick; Janel Johnson; Terhi Peuralinna; John Hardy; Pentti J Tienari; Andrew Singleton
Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD.
Neurology 2003;61(7):1000-2.
2003: Tarja Linnankivi; Taina Autti; S Helena Pihko; Mirja Somer; Pentti J Tienari; Kari O Wirtavuori; Leena Valanne
18q-syndrome: brain MRI shows poor differentiation of gray and white matter on T2-weighted images.
Journal of magnetic resonance imaging : JMRI 2003;18(4):414-9.
2003: Hannele Pihlaja; Terhi Rantamäki; Juhani Wikström; Marja-Liisa Sumelahti; M Laaksonen; Jorma Ilonen; Juhani Ruutiainen; T Pirttilä; Irina Elovaara; Mauri Reunanen; Satu Kuokkanen; Leena Peltonen; Keijo Koivisto; Pentti J Tienari
Linkage disequilibrium between the MBP tetranucleotide repeat and multiple sclerosis is restricted to a geographically defined subpopulation in Finland.
Genes and immunity 2003;4(2):138-46.
2003: Sergey Nejentsev; Mikko Laaksonen; Pentti J Tienari; Oscar Fernandez; Heather Cordell; Juhani Ruutiainen; Juhani Wikström; Tomi Pastinen; Satu Kuokkanen; Jan Hillert; Jorma Ilonen
Intercellular adhesion molecule-1 K469E polymorphism: study of association with multiple sclerosis.
Human immunology 2003;64(3):345-9.
2003: Marja-Liisa Sumelahti; Pentti J Tienari; Matti Hakama; Juhani Wikström
Multiple sclerosis in Finland: incidence trends and differences in relapsing remitting and primary progressive disease courses.
Journal of neurology, neurosurgery, and psychiatry 2003;74(1):25-8.
2002: Johanna Eerola; Jyrki Launes; Olli Hellström; Pentti J Tienari
Apolipoprotein E (APOE), PARKIN and catechol-O-methyltransferase (COMT) genes and susceptibility to sporadic Parkinson's disease in Finland.
Neuroscience letters 2002;330(3):296-8.
2002: Janna Saarela; Marlena Schoenberg Fejzo; Daniel Chen; Saara Finnilä; Maija Parkkonen; Satu Kuokkanen; Eric Sobel; Pentti J Tienari; Marja-Liisa Sumelahti; Juhani Wikström; Irina Elovaara; Keijo Koivisto; Tuula Pirttilä; Mauri Reunanen; Aarno Palotie; Leena Peltonen
Fine mapping of a multiple sclerosis locus to 2.5 Mb on chromosome 17q22-q24.
Human molecular genetics 2002;11(19):2257-67.
2002: Marja-Liisa Sumelahti; Pentti J Tienari; Juhani Wikström; T M Salminen; Matti Hakama
Survival of multiple sclerosis in Finland between 1964 and 1993.
Multiple sclerosis (Houndmills, Basingstoke, England) 2002;8(4):350-5.
2002: Karoliina Reunanen; Saara Finnilä; Mikko Laaksonen; Marja-Liisa Sumelahti; Juhani Wikström; Tomi Pastinen; Satu Kuokkanen; Janna Saarela; P Uimari; Juhani Ruutiainen; Jorma Ilonen; Leena Peltonen; Pentti J Tienari
Chromosome 19q13 and multiple sclerosis susceptibility in Finland: a linkage and two-stage association study.
Journal of neuroimmunology 2002;126(1-2):134-42.
2002: Liisa Myllykangas; Tuomo Polvikoski; Karoliina Reunanen; Fabienne Wavrant De-Vrieze; Clare Ellis; Dena Hernandez; Raimo Sulkava; Kimmo Kontula; Auli Verkkoniemi; Irma-Leena Notkola; John Hardy; Jordi Perez-Tur; Matti Haltia; Pentti J Tienari
ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain.
American journal of medical genetics 2002;114(3):288-91.
2002: Mikko Laaksonen; Tomi Pastinen; Minna Sjöroos; Satu Kuokkanen; Juhani Ruutiainen; Marja-Liisa Sumelahti; Helena Reijonen; Reijo Salonen; Juhani Wikström; Martin Panelius; Jukka Partanen; Pentti J Tienari; Jorma Ilonen
HLA class II associated risk and protection against multiple sclerosis-a Finnish family study.
Journal of neuroimmunology 2002;122(1-2):140-5.
2001: Liisa Myllykangas; Tuomo Polvikoski; Raimo Sulkava; Irma-Leena Notkola; Sari Rastas; Auli Verkkoniemi; Pentti J Tienari; Leena Niinistö; John Hardy; Jordi Pérez-Tur; Kimmo Kontula; Matti Haltia
Association of lipoprotein lipase Ser447Ter polymorphism with brain infarction: a population-based neuropathological study.
Annals of medicine 2001;33(7):486-92.
2001: Marja-Liisa Sumelahti; Pentti J Tienari; Juhani Wikström; Jukka U Palo; Matti Hakama
Increasing prevalence of multiple sclerosis in Finland.
Acta neurologica Scandinavica 2001;103(3):153-8.
2000: Liisa Myllykangas; Tuomo Polvikoski; Raimo Sulkava; Auli Verkkoniemi; Pentti J Tienari; Leena Niinistö; Kimmo Kontula; John Hardy; Matti Haltia; Jordi Pérez-Tur
Cardiovascular risk factors and Alzheimer's disease: a genetic association study in a population aged 85 or over.
Neuroscience letters 2000;292(3):195-8.
2000: Matt Baker; D Graff-Radford; F Wavrant-DeVrièze; Neill R Graff-Radford; Ronald C. Petersen; Emre Kokmen; Bradley Boeve; Liisa Myllykangas; Tuomo Polvikoski; Raimo Sulkava; A Verkoniemmi; Pentti J Tienari; Matti Haltia; John Hardy; Michael Hutton; Jordi Perez-Tur
No association between TAU haplotype and Alzheimer's disease in population or clinic based series or in familial disease.
Neuroscience letters 2000;285(2):147-9.
2000: Marja-Liisa Sumelahti; Pentti J Tienari; Juhani Wikström; Jukka U Palo; Matti Hakama
Regional and temporal variation in the incidence of multiple sclerosis in Finland 1979-1993.
Neuroepidemiology 2000;19(2):67-75.
1999: Pentti J Tienari; Karoliina Reunanen
Chromosome 19 locus apolipoprotein C-II association with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 1999;5(6):378.
1999: Liisa Myllykangas; Tuomo Polvikoski; Raimo Sulkava; Auli Verkkoniemi; Richard Crook; Pentti J Tienari; A K Pusa; Leena Niinistö; P O'Brien; Kimmo Kontula; John Hardy; Matti Haltia; Jordi Pérez-Tur
Genetic association of alpha2-macroglobulin with Alzheimer's disease in a Finnish elderly population.
Annals of neurology 1999;46(3):382-90.
1999: Taina Autti; M Muttilainen; Raili Raininko; Hannu Heiskala; Johanna Puranen; Anna-Maija Häkkinen; Pentti J Tienari; Pirkko Santavuori; P Suominen; Mirja Somer
Extensive cerebral white matter abnormality without clinical symptoms: a new hereditary condition?
Annals of neurology 1999;45(6):801-5.
1998: Pentti J Tienari; Satu Kuokkanen; Tomi Pastinen; Juhani Wikström; Antti Sajantila; M Sandberg-Wollheim; Jukka U Palo; Leena Peltonen
Golli-MBP gene in multiple sclerosis susceptibility.
Journal of neuroimmunology 1998;81(1-2):158-67.
1997: Satu Kuokkanen; M Gschwend; JD Rioux; Mark J Daly; Joseph D Terwilliger; Pentti J Tienari; Juhani Wikström; Jukka U Palo; L D Stein; T J Hudson; Eric S Lander; Leena Peltonen
Genomewide scan of multiple sclerosis in Finnish multiplex families.
American journal of human genetics 1997;61(6):1379-87.
1997: K Wansen; Tomi Pastinen; Satu Kuokkanen; Juhani Wikström; Jukka U Palo; Leena Peltonen; Pentti J Tienari
Immune system genes in multiple sclerosis: genetic association and linkage analyses on TCR beta, IGH, IFN-gamma and IL-1ra/IL-1 beta loci.
Journal of neuroimmunology 1997;79(1):29-36.
1996: Satu Kuokkanen; M Sundvall; Joseph D Terwilliger; Pentti J Tienari; Juhani Wikström; R Holmdahl; U Pettersson; Leena Peltonen
A putative vulnerability locus to multiple sclerosis maps to 5p14-p12 in a region syntenic to the murine locus Eae2.
Nature genetics 1996;13(4):477-80.
1994: Pentti J Tienari; Joseph D Terwilliger; J Ott; Jukka U Palo; Leena Peltonen
Two-locus linkage analysis in multiple sclerosis (MS).
Genomics 1994;19(2):320-5.
1994: Pentti J Tienari; Jukka U Palo; J Wikström; L Palotie
[Genes and multiple sclerosis].
Duodecim; lääketieteellinen aikakauskirja 1994;110(7):741-8.
1993: Pentti J Tienari; Juhani Wikström; S Koskimies; J Partanen; Jukka U Palo; Leena Peltonen
Reappraisal of HLA in multiple sclerosis: close linkage in multiplex families.
European journal of human genetics : EJHG 1993;1(4):257-68.
1992: Pentti J Tienari; Juhani Wikström; Antti Sajantila; Jukka U Palo; Leena Peltonen
Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene.
Lancet 1992;340(8826):987-91.
1992: Pentti J Tienari; Oili Salonen; Juhani Wikström; Leena Valanne; Jukka U Palo
Familial multiple sclerosis: MRI findings in clinically affected and unaffected siblings.
Journal of neurology, neurosurgery, and psychiatry 1992;55(10):883-6.
1991: Antti Sajantila; M Ström; B Budowle; Pentti J Tienari; Christian Ehnholm; Leena Peltonen
The distribution of the HLA-DQ alpha alleles and genotypes in the Finnish population as determined by the use of DNA amplification and allele specific oligonucleotides.
International journal of legal medicine 1991;104(4):181-4.