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Matti Tikkanen

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Co-Publications
Name
18
Ylikorkala, Olavi
13
Adlercreutz, Herman
10
Jauhiainen, Matti
9
Wähälä, Kristiina
9
Vihma, Veera
8
Vanhanen, Hannu
7
Korpela, Riitta
7
Kontula, Kimmo
7
Höckerstedt, Anna
6
Häyry, Pekka
6
Meng, QH
6
Palotie, Aarno
6
Xu, Chun-Fang
6
Vapaatalo, Heikki
6
Seppo, Leena

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Publications

TOP 3
Söderholm Päivi P; Koskela Anja H; Lundin Johan E; Tikkanen Matti J; Adlercreutz Herman C
Plasma pharmacokinetics of alkylresorcinol metabolites: new candidate biomarkers for whole-grain rye and wheat intake.
Paatela Hanna; Mervaala Eero; Deb Somdatta; Wähälä Kristiina; Tikkanen Matti J
HDL-associated dehydroepiandrosterone fatty acyl esters: enhancement of vasodilatory effect of HDL.
Faergeman Ole; Holme Ingar; Fayyad Rana; Bhatia Sonal; Grundy Scott M; Kastelein John J P; LaRosa John C; Larsen Mogens Lytken; Lindahl Christina; Olsson Anders G; Tikkanen Matti J; Waters David D; Pedersen Terje R;
Plasma triglycerides and cardiovascular events in the Treating to New Targets and Incremental Decrease in End-Points through Aggressive Lipid Lowering trials of statins in patients with coronary artery disease.

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All Publications

2009: Söderholm Päivi P; Koskela Anja H; Lundin Johan E; Tikkanen Matti J; Adlercreutz Herman C
Plasma pharmacokinetics of alkylresorcinol metabolites: new candidate biomarkers for whole-grain rye and wheat intake.
The American journal of clinical nutrition 2009;90(5):1167-71.
2009: Paatela Hanna; Mervaala Eero; Deb Somdatta; Wähälä Kristiina; Tikkanen Matti J
HDL-associated dehydroepiandrosterone fatty acyl esters: enhancement of vasodilatory effect of HDL.
Steroids 2009;74(10-11):814-8.
2009: Faergeman Ole; Holme Ingar; Fayyad Rana; Bhatia Sonal; Grundy Scott M; Kastelein John J P; LaRosa John C; Larsen Mogens Lytken; Lindahl Christina; Olsson Anders G; Tikkanen Matti J; Waters David D; Pedersen Terje R;
Plasma triglycerides and cardiovascular events in the Treating to New Targets and Incremental Decrease in End-Points through Aggressive Lipid Lowering trials of statins in patients with coronary artery disease.
The American journal of cardiology 2009;104(4):459-63.
2009: Holme Ingar; Strandberg Timo E; Faergeman Ole; Kastelein John J P; Olsson Anders G; Tikkanen Matti J; Larsen Mogens Lytken; Lindahl Christina; Pedersen Terje R;
Congestive heart failure is associated with lipoprotein components in statin-treated patients with coronary heart disease Insights from the Incremental Decrease in End points Through Aggressive Lipid Lowering Trial (IDEAL).
Atherosclerosis 2009;205(2):522-7.
2009: Holme Ingar; Szarek Michael; Cater Nilo B; Faergeman Ole; Kastelein John J P; Olsson Anders G; Tikkanen Matti J; Larsen Mogens Lytken; Lindahl Christina; Pedersen Terje R;
Adherence-adjusted efficacy with intensive versus standard statin therapy in patients with acute myocardial infarction in the IDEAL study.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2009;16(3):315-20.
2009: Tikkanen Matti J; Holme Ingar; Cater Nilo B; Szarek Michael; Faergeman Ole; Kastelein John J P; Olsson Anders G; Larsen Mogens Lytken; Lindahl Christina; Pedersen Terje R;
Comparison of efficacy and safety of atorvastatin (80 mg) to simvastatin (20 to 40 mg) in patients aged <65 versus >or=65 years with coronary heart disease (from the Incremental DEcrease through Aggressive Lipid Lowering [IDEAL] study).
The American journal of cardiology 2009;103(5):577-82.
2008: Wang Feng; Wang Wei; Wähälä Kristiina; Adlercreutz Herman; Ikonen Elina; Tikkanen Matti J
Role of lysosomal acid lipase in the intracellular metabolism of LDL-transported dehydroepiandrosterone-fatty acyl esters.
American journal of physiology. Endocrinology and metabolism 2008;295(6):E1455-61.
2008: Badeau Maija H; Badeau Robert; Jauhiainen Matti; Tikkanen Matti J
Steroid hormone-fatty acid esters and bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(11):1866-7.
2008: Appt Susan E; Törmälä Riina; Franke Adrian A; Mikkola Tomi S; Tikkanen Matti J; Ylikorkala Olavi; Clarkson Thomas B
Soy-tibolone combination - effect on lipids in postmenopausal monkeys and women.
Maturitas 2008;60(3-4):216-22.
2007: Törmälä R M; Appt S; Clarkson T B; Tikkanen M J; Ylikorkala O; Mikkola T S
Individual differences in equol production capability modulate blood pressure in tibolone-treated postmenopausal women: lack of effect of soy supplementation.
Climacteric : the journal of the International Menopause Society 2007;10(6):471-9.
2007: Badeau Maija; Vihma Veera; Mikkola Tomi S; Tiitinen Aila; Tikkanen Matti J
Estradiol fatty acid esters in adipose tissue and serum of pregnant and pre- and postmenopausal women.
The Journal of clinical endocrinology and metabolism 2007;92(11):4327-31.
2007: Badeau Robert M; Metso Jari; Tikkanen Matti J; Jauhiainen Matti
High-density lipoprotein-associated 17beta-estradiol fatty acyl ester uptake by Fu5AH hepatoma cells: implications of the roles of scavenger receptor class B, type I and the low-density lipoprotein receptor.
Biochimica et biophysica acta 2007;1771(10):1329-34.
2007: Koskela Anja; Linko-Parvinen Anna-Maria; Hiisivuori Perttu; Samaletdin Adile; Kamal-Eldin Afaf; Tikkanen Matti J; Adlercreutz Herman
Quantification of alkylresorcinol metabolites in urine by HPLC with coulometric electrode array detection.
Clinical chemistry 2007;53(7):1380-3.
2007: Linko-Parvinen Anna-Maria; Landberg Rikard; Tikkanen Matti J; Adlercreutz Herman; Peñalvo José L
Alkylresorcinols from whole-grain wheat and rye are transported in human plasma lipoproteins.
The Journal of nutrition 2007;137(5):1137-42.
2007: Badeau Robert; Jauhiainen Matti; Metso Jari; Nikander Eini; Tikkanen Matti J; Ylikorkala Olavi; Mikkola Tomi S
Effect of isolated isoflavone supplementation on ABCA1-dependent cholesterol efflux potential in postmenopausal women.
Menopause (New York, N.Y.) 2007;14(2):293-9.
2006: Miilunpohja Manna; Uphoff Andreas; Somerharju Pentti; Tiitinen Aila; Wähälä Kristiina; Tikkanen Matti J
Fatty acid esterification of lipoprotein-associated estrone in human plasma and follicular fluid.
The Journal of steroid biochemistry and molecular biology 2006;100(1-3):59-66.
2006: Korpela R; Tuomilehto J; Högström P; Seppo L; Piironen V; Salo-Väänänen P; Toivo J; Lamberg-Allardt C; Kärkkäinen M; Outila T; Sundvall J; Vilkkilä S; Tikkanen M J
Safety aspects and cholesterol-lowering efficacy of low fat dairy products containing plant sterols.
European journal of clinical nutrition 2006;60(5):633-42.
2006: Höckerstedt Anna; Jauhiainen Matti; Tikkanen Matti J
Estradiol fatty acid esterification is increased in high density lipoprotein subclass 3 isolated from hypertriglyceridemic subjects.
Atherosclerosis 2006;185(2):264-70.
2005: Badeau Maija; Tikkanen Matti J; Appt Susan E; Adlercreutz Herman; Clarkson Thomas B; Hoikkala Antti; Wähälä Kristiina; Mikkola Tomi S
Determination of plasma genistein fatty acid esters following administration of genistein or genistein 4'7-O-dioleate in monkeys.
Biochimica et biophysica acta 2005;1738(1-3):115-20.
2005: Seppo L; Lähteenmäki T; Tikkanen M J; Vanhanen H; Korpela R; Vapaatalo H
Effects of vitamin E on the toxicity of oxidized LDL on endothelial cells in vitro in smokers vs nonsmokers on diets rich in fish.
European journal of clinical nutrition 2005;59(11):1282-90.
2005: Badeau Maija; Adlercreutz Herman; Kaihovaara Pertti; Tikkanen Matti J
Estrogen A-ring structure and antioxidative effect on lipoproteins.
The Journal of steroid biochemistry and molecular biology 2005;96(3-4):271-8.
2005: Ropponen A; Aittomäki K; Vihma V; Tikkanen M J; Ylikorkala O
Effects of oral and transdermal estradiol administration on levels of sex hormone-binding globulin in postmenopausal women with and without a history of intrahepatic cholestasis of pregnancy.
The Journal of clinical endocrinology and metabolism 2005;90(6):3431-4.
2005: Vasankari Tommi; Ahotupa Markku; Viikari Jorma; Nuotio Ilpo; Vuorenmaa Tapio; Strandberg Timo; Vanhanen Hannu; Tikkanen Matti J
Effects of statin therapy on circulating conjugated dienes, a measure of LDL oxidation.
Atherosclerosis 2005;179(1):207-9.
2005: Ropponen A; Aittomäki K; Tikkanen M J; Ylikorkala O
Levels of serum C-reactive protein during oral and transdermal estradiol in postmenopausal women with and without a history of intrahepatic cholestasis of pregnancy.
The Journal of clinical endocrinology and metabolism 2005;90(1):142-6.
2005: Tikkanen M J
Plant sterols and stanols.
Handbook of experimental pharmacology 2005;(170):215-30.
2004: Kaaja Risto; Laivuori Hannele; Pulkki Pekka; Tikkanen Matti J; Hiilesmaa Vilho; Ylikorkala Olavi
Is there any link between insulin resistance and inflammation in established preeclampsia?
Metabolism: clinical and experimental 2004;53(11):1433-5.
2004: Höckerstedt Anna; Jauhiainen Matti; Tikkanen Matti J
Lecithin/cholesterol acyltransferase induces estradiol esterification in high-density lipoprotein, increasing its antioxidant potential.
The Journal of clinical endocrinology and metabolism 2004;89(10):5088-93.
2004: Nikander Eini; Tiitinen Aila; Laitinen Kalevi; Tikkanen Matti; Ylikorkala Olavi
Effects of isolated isoflavonoids on lipids, lipoproteins, insulin sensitivity, and ghrelin in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2004;89(7):3567-72.
2004: Vasankari Tommi; Ahotupa Markku; Viikari Jorma; Nuotio Ilpo; Strandberg Timo; Vanhanen Hannu; Gylling Helena; Miettinen Tatu; Tikkanen Matti J
Effect of 12-month statin therapy on antioxidant potential of LDL and serum antioxidant vitamin concentrations.
Annals of medicine 2004;36(8):618-22.
2004: Vihma Veera; Ropponen Anne; Aittomäki Kristiina; Ylikorkala Olavi; Tikkanen Matti J
Postmenopausal estrogen therapy and serum estradiol fatty acid esters in women with and without previous intrahepatic cholestasis of pregnancy.
Annals of medicine 2004;36(5):393-9.
2003: Strandberg Timo E; Ylikorkala Olavi; Tikkanen Matti J
Differing effects of oral and transdermal hormone replacement therapy on cardiovascular risk factors in healthy postmenopausal women.
The American journal of cardiology 2003;92(2):212-4.
2003: Vihma Veera; Tiitinen Aila; Ylikorkala Olavi; Tikkanen Matti J
Quantitative determination of estradiol fatty acid esters in lipoprotein fractions in human blood.
The Journal of clinical endocrinology and metabolism 2003;88(6):2552-5.
2003: Kaamanen Maija; Adlercreutz Herman; Jauhiainen Matti; Tikkanen Matti J
Accumulation of genistein and lipophilic genistein derivatives in lipoproteins during incubation with human plasma in vitro.
Biochimica et biophysica acta 2003;1631(2):147-52.
2003: Vihma Veera; Vehkavaara Satu; Yki-Järvinen Hannele; Hohtari Hannele; Tikkanen Matti J
Differential effects of oral and transdermal estradiol treatment on circulating estradiol fatty acid ester concentrations in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2003;88(2):588-93.
2002: Tikkanen Matti J; Vihma Veera; Jauhiainen Matti; Höckerstedt Anna; Helisten Hannamaarit; Kaamanen Maija
Lipoprotein-associated estrogens.
Cardiovascular research 2002;56(2):184-8.
2002: Tikkanen M J; Vihma V; Höckerstedt A; Jauhiainen M; Helisten H; Kaamanen M
Lipophilic oestrogen derivatives contained in lipoprotein particles.
Acta physiologica Scandinavica 2002;176(2):117-21.
2002: Höckerstedt Anna; Tikkanen Matti J; Jauhiainen Matti
LCAT facilitates transacylation of 17 beta-estradiol in the presence of HDL3 subfraction.
Journal of lipid research 2002;43(3):392-7.
2001: Tikkanen M J; Högström P; Tuomilehto J; Keinänen-Kiukaanniemi S; Sundvall J; Karppanen H
Effect of a diet based on low-fat foods enriched with nonesterified plant sterols and mineral nutrients on serum cholesterol.
The American journal of cardiology 2001;88(10):1157-62.
2001: Helisten H; Höckerstedt A; Wähälä K; Tiitinen A; Adlercreutz H; Jauhiainen M; Tikkanen M J
Accumulation of high-density lipoprotein-derived estradiol-17beta fatty acid esters in low-density lipoprotein particles.
The Journal of clinical endocrinology and metabolism 2001;86(3):1294-300.
2001: Vihma V; Adlercreutz H; Tiitinen A; Kiuru P; Wähälä K; Tikkanen M J
Quantitative determination of estradiol fatty acid esters in human pregnancy serum and ovarian follicular fluid.
Clinical chemistry 2001;47(7):1256-62.
2000: Strandberg T E; Vanhanen H; Tikkanen M J
Associations between change in C-reactive protein and serum lipids during statin treatment.
Annals of medicine 2000;32(8):579-83.
2000: Tikkanen M J; Adlercreutz H
Dietary soy-derived isoflavone phytoestrogens. Could they have a role in coronary heart disease prevention?
Biochemical pharmacology 2000;60(1):1-5.
2000: Nevala R; Seppo L; Tikkanen M J; Laakso J; Vanhanen H; Vapaatalo H; Korpela R
Dietary fatty acid composition influences the degree of human LDL oxidation, but has only minor effects on vascular tone in a bioassay system.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2000;10(3):126-36.
2000: Seppo L; Karjala K; Nevala R; Korpela R; Lähteenmäki T; Solatunturi E; Tikkanen M J; Vapaatalo H
A long-term fish diet modifies the toxic properties of human partially oxidized LDL on vascular preparations in vitro.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2000;51(2):251-65.
2000: Liu J; Heikkilä P; Meng Q H; Kahri A I; Tikkanen M J; Voutilainen R
Expression of low and high density lipoprotein receptor genes in human adrenals.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(6):677-82.
2000: Lähteenmäki T A; Seppo L; Laakso J; Korpela R; Vanhanen H; Tikkanen M J; Vapaatalo H
Oxidized LDL from subjects with different dietary habits modifies atherogenic processes in endothelial and smooth muscle cells.
Life sciences 2000;66(5):455-65.
1999: Korpela R; Seppo L; Laakso J; Lilja J; Karjala K; Lähteenmäki T; Solatunturi E; Vapaatalo H; Tikkanen M J
Dietary habits affect the susceptibility of low-density lipoprotein to oxidation.
European journal of clinical nutrition 1999;53(10):802-7.
1999: Laivuori H M; Laakso M; Tikkanen M J; Cacciatore B; Ylikorkala R O; Kaaja R J
Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia.
Journal of hypertension 1999;17(8):1189-94.
1999: Meng Q H; Höckerstedt A; Heinonen S; Wähälä K; Adlercreutz H; Tikkanen M J
Antioxidant protection of lipoproteins containing estrogens: in vitro evidence for low- and high-density lipoproteins as estrogen carriers.
Biochimica et biophysica acta 1999;1439(3):331-40.
1999: Kaaja R; Laivuori H; Laakso M; Tikkanen M J; Ylikorkala O
Evidence of a state of increased insulin resistance in preeclampsia.
Metabolism: clinical and experimental 1999;48(7):892-6.
1999: Strandberg T E; Vanhanen H; Tikkanen M J
Frequency of lipid-lowering therapy after a coronary event in Helsinki, Finland.
The American journal of cardiology 1999;84(1):95, A8.
1999: Meng Q H; Lewis P; Wähälä K; Adlercreutz H; Tikkanen M J
Incorporation of esterified soybean isoflavones with antioxidant activity into low density lipoprotein.
Biochimica et biophysica acta 1999;1438(3):369-76.
1999: Wartiovaara U; Perola M; Mikkola H; Tötterman K; Savolainen V; Penttilä A; Grant P J; Tikkanen M J; Vartiainen E; Karhunen P J; Peltonen L; Palotie A
Association of FXIII Val34Leu with decreased risk of myocardial infarction in Finnish males.
Atherosclerosis 1999;142(2):295-300.
1999: Strandberg T E; Vanhanen H; Tikkanen M J
Effect of statins on C-reactive protein in patients with coronary artery disease.
Lancet 1999;353(9147):118-9.
1999: Meng Q H; Wähälä K; Adlercreutz H; Tikkanen M J
Antiproliferative efficacy of lipophilic soy isoflavone phytoestrogens delivered by low density lipoprotein particles into cultured U937 cells.
Life sciences 1999;65(16):1695-705.
1998: Cacciatore B; Paakkari I; Toivonen J; Tikkanen M J; Ylikorkala O
Randomized comparison of oral and transdermal hormone replacement on carotid and uterine artery resistance to blood flow.
Obstetrics and gynecology 1998;92(4 Pt 1):563-8.
1998: Ilmonen M; Knudsen P; Taskinen M R; Tikkanen M J
Genetic variation in the amino-terminal part of apolipoprotein B: studies in hyperlipidemic patients.
Atherosclerosis 1998;138(2):367-74.
1998: Ylikorkala O; Cacciatore B; Paakkari I; Tikkanen M J; Viinikka L; Toivonen J
The long-term effects of oral and transdermal postmenopausal hormone replacement therapy on nitric oxide, endothelin-1, prostacyclin, and thromboxane.
Fertility and sterility 1998;69(5):883-8.
1998: Tikkanen M J; Laakso M; Ilmonen M; Helve E; Kaarsalo E; Kilkki E; Saltevo J
Treatment of hypercholesterolemia and combined hyperlipidemia with simvastatin and gemfibrozil in patients with NIDDM. A multicenter comparison study.
Diabetes care 1998;21(4):477-81.
1998: Tikkanen M J; Wähälä K; Ojala S; Vihma V; Adlercreutz H
Effect of soybean phytoestrogen intake on low density lipoprotein oxidation resistance.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3106-10.
1998: Lähteenmäki T A; Korpela R; Tikkanen M J; Karjala K; Laakso J; Solatunturi E; Vapaatalo H
Proliferative effects of oxidized low-density lipoprotein on vascular smooth muscle cells: role of dietary habits.
Life sciences 1998;63(12):995-1003.
1997: Meng Q H; Pajukanta P; Valsta L; Aro A; Pietinen P; Tikkanen M J
Influence of apolipoprotein A-1 promoter polymorphism on lipid levels and responses to dietary change in Finnish adults.
Journal of internal medicine 1997;241(5):373-8.
1997: Kujala U M; Ahotupa M; Vasankari T J; Kaprio J; Tikkanen M J
Familial aggregation of LDL oxidation.
Scandinavian journal of clinical and laboratory investigation 1997;57(2):141-6.
1997: Ilmonen M; Ebeling T; Viikari J; Ojala J P; Tikkanen M J
Screening of the 3' two-thirds of the coding area of the apo B gene in Finnish hypercholesterolemic patients report of six new genetic variants.
Atherosclerosis 1997;128(2):191-9.
1996: Tikkanen M J
Statins: within-group comparisons, statin escape and combination therapy.
Current opinion in lipidology 1996;7(6):385-8.
1996: Meng Q H; Pajukanta P; Ilmonen M; Schuster H; Schewe C K; Andersson L C; Tikkanen M J
Analysis of novel apolipoprotein B mutations using a modified U937 cell line LDL binding assay.
Clinica chimica acta; international journal of clinical chemistry 1996;256(1):27-36.
1996: Laivuori H; Tikkanen M J; Ylikorkala O
Hyperinsulinemia 17 years after preeclamptic first pregnancy.
The Journal of clinical endocrinology and metabolism 1996;81(8):2908-11.
1996: Tikkanen M J
Estrogens, progestins and lipid metabolism.
Maturitas 1996;23 Suppl():S51-5.
1996: Pajukanta P E; Valsta L M; Aro A; Pietinen P; Heliö T; Tikkanen M J
The effects of the apolipoprotein B signal peptide (ins/del) and XbaI polymorphisms on plasma lipid responses to dietary change.
Atherosclerosis 1996;122(1):1-10.
1996: Laaksonen R; Jokelainen K; Laakso J; Sahi T; Harkonen M; Tikkanen M J; Himberg J J
The effect of simvastatin treatment on natural antioxidants in low-density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle.
The American journal of cardiology 1996;77(10):851-4.
1996: Tikkanen M J
The menopause and hormone replacement therapy: lipids, lipoproteins, coagulation and fibrinolytic factors.
Maturitas 1996;23(2):209-16.
1995: Tikkanen M J
Selection of appropriate type and intensity of lipid-lowering therapy.
Current opinion in lipidology 1995;6(6):360-4.
1995: Tikkanen M; Huttunen J K; Pajukanta P E; Pietinen P
Apolipoprotein E polymorphism and dietary plasma cholesterol response.
The Canadian journal of cardiology 1995;11 Suppl G():93G-96G.
1995: Koskinen P; Kupari M; Virolainen J; Stjernvall J; Jolkkonen J; Tuomilehto J; Tikkanen M J
Heart rate and blood pressure variability and baroreflex sensitivity in hypercholesterolaemia.
Clinical physiology (Oxford, England) 1995;15(5):483-9.
1995: Ilmonen M; Heliö T; Bütler R; Palotie A; Pietinen P; Huttunen J K; Tikkanen M J
Two new immunogenetic polymorphisms of the apoB gene and their effect on serum lipid levels and responses to changes in dietary fat intake.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(9):1287-93.
1995: Sobel E; Louhija J; Sulkava R; Davanipour Z; Kontula K; Miettinen H; Tikkanen M; Kainulainen K; Tilvis R
Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians.
Neurology 1995;45(5):903-7.
1995: Laaksonen R; Riihimäki A; Laitila J; Mårtensson K; Tikkanen M J; Himberg J J
Serum and muscle tissue ubiquinone levels in healthy subjects.
The Journal of laboratory and clinical medicine 1995;125(4):517-21.
1995: Kaaja R; Tikkanen M J; Viinikka L; Ylikorkala O
Serum lipoproteins, insulin, and urinary prostanoid metabolites in normal and hypertensive pregnant women.
Obstetrics and gynecology 1995;85(3):353-6.
1995: Tilly-Kiesi M; Räisänen-Sokolowski A; Ustinov J; Myllärniemi M; Tikkanen M J; Häyry P
Hyperlipidemia enhances chronic rejection in experimental rat model.
Transplantation proceedings 1995;27(1):582.
1995: Vuorio A F; Ojala J P; Sarna S; Turtola H; Tikkanen M J; Kontula K
Heterozygous familial hypercholesterolaemia: the influence of the mutation type of the low-density-lipoprotein receptor gene and PvuII polymorphism of the normal allele on serum lipid levels and response to lovastatin treatment.
Journal of internal medicine 1995;237(1):43-8.
1995: Laaksonen R; Jokelainen K; Sahi T; Tikkanen M J; Himberg J J
Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans.
Clinical pharmacology and therapeutics 1995;57(1):62-6.
1994: Räisänen-Sokolowski A; Tilly-Kiesi M; Ustinov J; Mennander A; Paavonen T; Tikkanen M J; Häyry P
Hyperlipidemia accelerates allograft arteriosclerosis (chronic rejection) in the rat.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(12):2032-42.
1994: Heliö T; Palotie A; Sane T; Tikkanen M J; Kontula K
No evidence for linkage between familial hypertriglyceridemia and apolipoprotein B, apolipoprotein C-III or lipoprotein lipase genes.
Human genetics 1994;94(3):271-8.
1994: Louhija J; Miettinen H E; Kontula K; Tikkanen M J; Miettinen T A; Tilvis R S
Aging and genetic variation of plasma apolipoproteins. Relative loss of the apolipoprotein E4 phenotype in centenarians.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(7):1084-9.
1994: Tikkanen M J; Heliö T
From Ag phenotyping to molecular genetics: apolipoprotein B, serum lipid levels and coronary artery disease in Finland.
Clinical genetics 1994;46(1 Spec No):71-6.
1994: Kupari M; Hekali P; Keto P; Poutanen V P; Tikkanen M J; Standerstkjöld-Nordenstam C G
Relation of aortic stiffness to factors modifying the risk of atherosclerosis in healthy people.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(3):386-94.
1994: Isoniemi H; Nurminen M; Tikkanen M J; von Willebrand E; Krogerus L; Ahonen J; Eklund B; Höckerstedt K; Salmela K; Häyry P
Risk factors predicting chronic rejection of renal allografts.
Transplantation 1994;57(1):68-72.
1994: Laaksonen R; Ojala J P; Tikkanen M J; Himberg J J
Serum ubiquinone concentrations after short- and long-term treatment with HMG-CoA reductase inhibitors.
European journal of clinical pharmacology 1994;46(4):313-7.
1994: Ilmonen M; Heliö T; Ebeling T; Pyörälä K; Uusitupa M; Palotie A; Tikkanen M J
Screening for mutations in the exon 26 of the apolipoprotein B gene in hypercholesterolemic Finnish families by the single-strand conformation polymorphism method.
Human mutation 1994;4(3):217-23.
1993: Kupari M; Virolainen J; Koskinen P; Tikkanen M J
Short-term heart rate variability and factors modifying the risk of coronary artery disease in a population sample.
The American journal of cardiology 1993;72(12):897-903.
1993: Isoniemi H M; Ahonen J; Tikkanen M J; von Willebrand E O; Krogerus L; Eklund B H; Höckerstedt K V; Salmela K E; Häyry P J
Long-term consequences of different immunosuppressive regimens for renal allografts.
Transplantation 1993;55(3):494-9.
1993: Tilly-Kiesi M; Mattila S P; Tikkanen M J
Effects of lovastatin on high-density lipoprotein subfractions in hypercholesterolemic patients with peripheral vascular disease.
Angiology 1993;44(2):129-37.
1993: Mennander A; Tikkanen M J; Räisänen-Sokolowski A; Paavonen T; Ustinov J; Häyry P
Chronic rejection in rat aortic allografts. IV. Effect of hypercholesterolemia in allograft arteriosclerosis.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1993;12(1 Pt 1):123-31; discussion 131-2.
1993: Saure A; Hirvonen E; Tikkanen M J; Viinikka L; Ylikorkala O
A novel oestradiol--desogestrel preparation for hormone replacement therapy: effects on hormones, lipids, bone, climacteric symptoms and endometrium.
Maturitas 1993;16(1):1-12.
1992: Tikkanen M J; Heliö T
Genetic variants of apolipoprotein B: relation to serum lipid levels and coronary artery disease among the Finns.
Annals of medicine 1992;24(5):357-61.
1992: Tilly-Kiesi M; Tikkanen M J
Effects of lovastatin and gemfibrozil on high-density lipoprotein subfraction density and composition in patients with familial hypercholesterolemia.
The Journal of laboratory and clinical medicine 1992;120(1):103-10.
1992: Huovinen K J; Lähteenmäki P; Kärkkäinen J; Tikkanen M J
Lynestrenol induced therapeutic amenorrhea: effects of dose reduction on serum sex-hormones and lipids.
Acta obstetricia et gynecologica Scandinavica 1992;71(3):175-80.
1992: Kauppinen-Mäkelin R; Kuusi T; Ylikorkala O; Tikkanen M J
Contraceptives containing desogestrel or levonorgestrel have different effects on serum lipoproteins and post-heparin plasma lipase activities.
Clinical endocrinology 1992;36(2):203-9.
1992: Heliö T; Palotie A; Tötterman K J; Ott J; Kauppinen-Mäkelin R; Tikkanen M J
Lack of association between the apolipoprotein B gene 3' hypervariable region alleles and coronary artery disease in Finnish patients with angiographically documented coronary artery disease.
Journal of internal medicine 1992;231(1):49-57.
1992: Dunning A M; Renges H H; Xu C F; Peacock R; Brasseur R; Laxer G; Tikkanen M J; Bütler R; Saha N; Hamsten A
Two amino acid substitutions in apolipoprotein B are in complete allelic association with the antigen group (x/y) polymorphism: evidence for little recombination in the 3' end of the human gene.
American journal of human genetics 1992;50(1):208-21.
1992: Talmud P J; Boerwinkle E; Xu C F; Tikkanen M J; Pietinen P; Huttunen J K; Humphries S
Dietary intake and gene variation influence the response of plasma lipids to dietary intervention.
Genetic epidemiology 1992;9(4):249-60.
1991: Ojala J P; Helve E; Ehnholm C; Aalto-Setälä K; Kontula K K; Tikkanen M J
Effect of apolipoprotein E polymorphism and XbaI polymorphism of apolipoprotein B on response to lovastatin treatment in familial and non-familial hypercholesterolaemia.
Journal of internal medicine 1991;230(5):397-405.
1991: Tilly-Kiesi M K; Tikkanen M J
Differential low density lipoprotein hydrated density distribution in female and male patients with familial hypercholesterolemia.
Clinica chimica acta; international journal of clinical chemistry 1991;201(1-2):65-74.
1991: Tilly-Kiesi M; Tikkanen M J
Low density lipoprotein density and composition in hypercholesterolaemic men treated with HMG CoA reductase inhibitors and gemfibrozil.
Journal of internal medicine 1991;229(5):427-34.
1991: Isoniemi H; Tikkanen M; Häyry P; Eklund B; Höckerstedt K; Salmela K; Ahonen J
Lipid profiles with triple drug immunosuppressive therapy and with double drug combinations after renal transplantation and stable graft function.
Transplantation proceedings 1991;23(1 Pt 2):1029-31.
1991: Tikkanen M J; Ojala J P; Helve E
Lovastatin and gemfibrozil in the treatment of type 2a and type 2b hyperlipoproteinemia.
European journal of clinical pharmacology 1991;40 Suppl 1():S23-5.
1991: Huovinen K; Tikkanen M J; Autio S; Härkönen T; Lommi L; Varonen S; Wilska M L
Serum lipids and lipoproteins during therapeutic amenorrhea induced by lynestrenol and depot-medroxyprogesterone acetate.
Acta obstetricia et gynecologica Scandinavica 1991;70(4-5):349-54.
1990: Xu C F; Tikkanen M J; Huttunen J K; Pietinen P; Bütler R; Humphries S; Talmud P
Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels.
Journal of lipid research 1990;31(7):1255-61.
1990: Hämäläinen T; Palotie A; Aalto-Setälä K; Kontula K; Tikkanen M J
Absence of familial defective apolipoprotein B-100 in Finnish patients with elevated serum cholesterol.
Atherosclerosis 1990;82(3):177-83.
1990: Ojala J P; Helve E; Karjalainen K; Tarkkanen A; Tikkanen M J
Long-term maintenance of therapeutic response to lovastatin in patients with familial and non-familial hypercholesterolemia: a 3-year follow-up.
Atherosclerosis 1990;82(1-2):85-95.
1990: Tikkanen M J; Xu C F; Hämäläinen T; Talmud P; Sarna S; Huttunen J K; Pietinen P; Humphries S
XbaI polymorphism of the apolipoprotein B gene influences plasma lipid response to diet intervention.
Clinical genetics 1990;37(5):327-34.
1990: Tikkanen M J
Plasma lipoproteins and atherosclerosis.
The Journal of diabetic complications 1990;4(2):35-8.
1990: Huovinen K; Tikkanen M J; Varonen S; Wilska M L; Westermarck T; Vesterinen H
The effect of peroral lynestrenol on serum lipids and lipoproteins in therapeutic amenorrhea of mentally retarded women.
Acta obstetricia et gynecologica Scandinavica 1990;69(1):35-40.
1990: Ojala J P; Helve E; Tikkanen M J
Treatment of combined hyperlipidemia with lovastatin versus gemfibrozil: a comparison study.
Cardiology 1990;77 Suppl 4():39-49.
1990: Xu C F; Boerwinkle E; Tikkanen M J; Huttunen J K; Humphries S E; Talmud P J
Genetic variation at the apolipoprotein gene loci contribute to response of plasma lipids to dietary change.
Genetic epidemiology 1990;7(4):261-75.
1989: Xu C F; Nanjee N; Tikkanen M J; Huttunen J K; Pietinen P; Bütler R; Angelico F; Del Ben M; Mazzarella B; Antonio R
Apolipoprotein B amino acid 3611 substitution from arginine to glutamine creates the Ag (h/i) epitope: the polymorphism is not associated with differences in serum cholesterol and apolipoprotein B levels.
Human genetics 1989;82(4):322-6.
1988: Tikkanen M J; Helve E; Jäättelä A; Kaarsalo E; Lehtonen A; Malbecq W; Oksa H; Pääkkönen P; Salmi J; Veharanta T
Comparison between lovastatin and gemfibrozil in the treatment of primary hypercholesterolemia: the Finnish Multicenter Study.
The American journal of cardiology 1988;62(15):35J-43J.
1988: Aalto-Setälä K; Tikkanen M J; Taskinen M R; Nieminen M; Holmberg P; Kontula K
XbaI and c/g polymorphisms of the apolipoprotein B gene locus are associated with serum cholesterol and LDL-cholesterol levels in Finland.
Atherosclerosis 1988;74(1-2):47-54.
1988: Helve E; Tikkanen M J
Comparison of lovastatin and probucol in treatment of familial and non-familial hypercholesterolemia: different effects on lipoprotein profiles.
Atherosclerosis 1988;72(2-3):189-97.
1988: Dunning A M; Tikkanen M J; Ehnholm C; Bütler R; Humphries S E
Relationships between DNA and protein polymorphisms of apolipoprotein B.
Human genetics 1988;78(4):325-9.
1988: Tikkanen M J
Hypercholesterolaemia in the elderly: is drug treatment justified?
European heart journal 1988;9 Suppl D():79-82.
1987: Ylikorkala O; Kuusi T; Tikkanen M J; Viinikka L
Desogestrel- and levonorgestrel-containing oral contraceptives have different effects on urinary excretion of prostacyclin metabolites and serum high density lipoproteins.
The Journal of clinical endocrinology and metabolism 1987;65(6):1238-42.
1987: Tikkanen M J; Helve E; Nikkilä E A
Treatment of familial and non-familial hypercholesterolaemia: a review of HMG-CoA reductase inhibitors and probucol.
European heart journal 1987;8 Suppl E():97-101.

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