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Stephen Tilley

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Xiaoyang Hua; Corey Jania; Catherine Ledent; Tatiana Acosta; Kelly D Chason; Stephen L Tilley
Gs-coupled adenosine receptors differentially limit antigen-induced mast cell activation.
Xiaoyang Hua; Catherine Ledent; Warren C Naselsky; Brent A Senior; William D Bennett; Stephen L Tilley
Adenosine increases nasal mucociliary clearance rate in mice through A2A and A2B adenosine receptors.
Dovenia S Ponnoth; Stephen L Tilley; Catherine Ledent; Mohammed A Nayeem; S Jamal Mustafa
CYP-epoxygenases contribute to A2A receptor-mediated aortic relaxation via sarcolemmal KATP channels.

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All Publications

2013: Xiaoyang Hua; Corey Jania; Catherine Ledent; Tatiana Acosta; Kelly D Chason; Stephen L Tilley
Gs-coupled adenosine receptors differentially limit antigen-induced mast cell activation.
The Journal of pharmacology and experimental therapeutics 2013;344(2):426-35.
2013: Xiaoyang Hua; Catherine Ledent; Warren C Naselsky; Brent A Senior; William D Bennett; Stephen L Tilley
Adenosine increases nasal mucociliary clearance rate in mice through A2A and A2B adenosine receptors.
The Laryngoscope 2013;123(2):306-10.
2012: Dovenia S Ponnoth; Stephen L Tilley; Catherine Ledent; Mohammed A Nayeem; S Jamal Mustafa
CYP-epoxygenases contribute to A2A receptor-mediated aortic relaxation via sarcolemmal KATP channels.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;303(10):R1003-10.
2012: Willie J Brickey; Xiaoyang Hua; Sushmita Jha; Suzanne L Kirby; Isabel P Neuringer; Gregory D Sempowski; Stephen L Tilley; William Walton; Ellis Y Wang; Xuebin Yang; Jenny P-Y Ting
MyD88 provides a protective role in long-term radiation-induced lung injury.
International journal of radiation biology 2012;88(4):335-47.
2012: Irving C Allen; W June Brickey; Xiaoyang Hua; Corey M Jania; Beverly H Koller; Mildred Kwan; Erin M Tekeppe; Stephen L Tilley; Justin E Wilson; Jenny P-Y Ting
Analysis of NLRP3 in the development of allergic airway disease in mice.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(6):2884-93.
2012: Dovenia S Ponnoth; Stephen L Tilley; Darryl C Zeldin; Swati S Kunduri; Catherine Ledent; Mohammed A Nayeem; S Jamal Mustafa
Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;302(4):R400-8.
2012: Irving C Allen; Janelle C Arthur; Justin B Callaway; Corey M Jania; John David Lich; Reid A Roberts; Stephen L Tilley; Jenny P-Y Ting
Characterization of NLRP12 during the development of allergic airway disease in mice.
PloS one 2012;7(1):e30612.
2011: Maryam Sharifi Sanjani; Bunyen Teng; Stephen L Tilley; Thomas Krahn; Catherine Ledent; S Jamal Mustafa
Contributions of A2A and A2B adenosine receptors in coronary flow responses in relation to the KATP channel using A2B and A2A/2B double-knockout mice.
American journal of physiology. Heart and circulatory physiology 2011;301(6):H2322-33.
2011: Mohammed S El-Awady; Daniel Fil; Habib R Ansari; Stephen L Tilley; S Jamal Mustafa
NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice.
The Journal of pharmacology and experimental therapeutics 2011;338(2):711-7.
2011: Xuebin Yang; Stephen L Tilley; William Walton; A William Blackstock; Donald N Cook; Christopher A Haskell; richard horuk; Xiaoyang Hua; Suzanne L Kirby
The chemokine, CCL3, and its receptor, CCR1, mediate thoracic radiation-induced pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2011;45(1):127-35.
2011: Xiaoyang Hua; Warren C Naselsky; Janki Y Patel; Kelly D Chason; Stephen L Tilley
IL-4 amplifies the pro-inflammatory effect of adenosine in human mast cells by changing expression levels of adenosine receptors.
PloS one 2011;6(9):e24947.
2011: Stephen L Tilley
Methylxanthines in asthma.
Handbook of experimental pharmacology 2011;(200):439-56.
2010: Dovenia S Ponnoth; Ahmed Nadeem; Stephen L Tilley; S Jamal Mustafa
Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma.
American journal of physiology. Heart and circulatory physiology 2010;299(1):H81-7.
2010: Martina Kovarova; Anne M Latour; Kelly D Chason; Stephen L Tilley; Beverly H Koller
Human embryonic stem cells: a source of mast cells for the study of allergic and inflammatory diseases.
Blood 2010;115(18):3695-703.
2010: Xiaoyang Hua; Kirby L Zeman; Bingqing Zhou; Qingquan Hua; Brent A Senior; Stephen L Tilley; William D Bennett
Noninvasive real-time measurement of nasal mucociliary clearance in mice by pinhole gamma scintigraphy.
Journal of applied physiology (Bethesda, Md. : 1985) 2010;108(1):189-96.
2009: Ilona Jaspers; Patricia A Sheridan; Wenli Zhang; Luisa E Brighton; Kelly D Chason; Xiaoyang Hua; Stephen L Tilley
Exacerbation of allergic inflammation in mice exposed to diesel exhaust particles prior to viral infection.
Particle and fibre toxicology 2009;6():22.
2008: Xiaoyang Hua; Kelly D Chason; Bertil B. Fredholm; Deepak A Deshpande; Raymond B Penn; Stephen L Tilley
Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells.
The Journal of allergy and clinical immunology 2008;122(1):107-13, 113.e1-7.
2008: Abduelhakem Ben Addi; Anne Lefort; Xiaoyang Hua; Frédérick Libert; David Communi; Catherine Ledent; Pascale Macours; Stephen L Tilley; Jean-Marie Boeynaems; Bernard Robaye
Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor.
European journal of immunology 2008;38(6):1610-20.
2008: Marcus A Mall; Jack R Harkema; Joanna B Trojanek; Diana Treis; Alessandra Livraghi; Susanne Schubert; Zhe Zhou; Silvia M Kreda; Stephen L Tilley; Elizabeth J Hudson; Wanda O Neal; Richard C Boucher
Development of chronic bronchitis and emphysema in beta-epithelial Na+ channel-overexpressing mice.
American journal of respiratory and critical care medicine 2008;177(7):730-42.
2008: Lan G Coffman; Julie C Brown; David A Johnson; Narayanan Parthasarathy; Ralph B D'Agostino; Mark Lively; Xiaoyang Hua; Stephen L Tilley; Werner Muller-Esterl; Mark C Willingham; Frank M Torti; Suzy V Torti
Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin.
American journal of physiology. Lung cellular and molecular physiology 2008;294(3):L505-15.
2007: Habib R Ansari; Ahmed Nadeem; Stephen L Tilley; S Jamal Mustafa
Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta.
American journal of physiology. Heart and circulatory physiology 2007;293(6):H3448-55.
2007: Xiaoyang Hua; Christopher J Erikson; Kelly D Chason; Craig N Rosebrock; Deepak A Deshpande; Raymond B Penn; Stephen L Tilley
Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice.
American journal of physiology. Lung cellular and molecular physiology 2007;293(1):L25-32.
2007: Stephen L Tilley; Maisa Jaradat; Cliona Stapleton; Darlene Dixon; Xiaoyang Hua; Christopher J Erikson; Joshua G McCaskill; Kelly D Chason; Grace Liao; Leigh A Jania; Beverly H Koller; Anton M Jetten
Retinoid-related orphan receptor gamma controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):3208-18.
2007: Xiaoyang Hua; Martina Kovarova; Kelly D Chason; MyTrang Nguyen; Beverly H Koller; Stephen L Tilley
Enhanced mast cell activation in mice deficient in the A2b adenosine receptor.
The Journal of experimental medicine 2007;204(1):117-28.
2006: Maisa Jaradat; Cliona Stapleton; Stephen L Tilley; Darlene Dixon; Christopher J Erikson; Joshua G McCaskill; Hong Soon Kang; Martin Angers; Grace Liao; Jennifer Collins; Sherry F Grissom; Anton M Jetten
Modulatory role for retinoid-related orphan receptor alpha in allergen-induced lung inflammation.
American journal of respiratory and critical care medicine 2006;174(12):1299-309.
2006: Joshua G McCaskill; Kelly D Chason; Xiaoyang Hua; Isabel P Neuringer; Andrew J Ghio; William K Funkhouser; Stephen L Tilley
Pulmonary immune responses to Propionibacterium acnes in C57BL/6 and BALB/c mice.
American journal of respiratory cell and molecular biology 2006;35(3):347-56.
2006: Alysia Kern Lovgren; Leigh A Jania; John M Hartney; Kelly K Parsons; Laurent P Audoly; garret fitzgerald; Stephen L Tilley; Beverly H Koller
COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2006;291(2):L144-56.
2006: John M Hartney; Kenneth G Coggins; Stephen L Tilley; Leigh A Jania; Alysia Kern Lovgren; Laurent P Audoly; Beverly H Koller
Prostaglandin E2 protects lower airways against bronchoconstriction.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L105-13.
2005: Manhong Guo; Rodolfo M Pascual; Siwei Wang; Mary F Fontana; Cathryn A Valancius; Reynold A Panettieri; Stephen L Tilley; Raymond B Penn
Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms.
Biochemistry 2005;44(42):13771-82.
2005: Stephen L Tilley; Richard C Boucher
A1 antagonism in asthma: better than coffee?
The Journal of clinical investigation 2005;115(1):13-6.
2004: Jennifer L Goulet; Amy J Pace; Mikelle Key-Solle; Robert S Byrum; MyTrang Nguyen; Stephen L Tilley; Scott G Morham; Robert Langenbach; Jeffrey L Stock; John McNeish; Oliver Smithies; Thomas M Coffman; Beverly H Koller
E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1321-6.
2003: Hongyan Zhong; Sergiy G Shlykov; Jose G Molina; Barbara M Sanborn; Marlene A Jacobson; Stephen L Tilley; Michael R Blackburn
Activation of murine lung mast cells by the adenosine A3 receptor.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):338-45.
2003: Stephen L Tilley; Mindy Tsai; Cara M Williams; Z-S Wang; Christopher J Erikson; Stephen J Galli; Beverly H Koller
Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):331-7.
2003: Stephen L Tilley; John M Hartney; Christopher J Erikson; Corey Jania; MyTrang Nguyen; Jeffrey Stock; John McNeisch; Cathryn A Valancius; Reynold A Panettieri; Raymond B Penn; Beverly H Koller
Receptors and pathways mediating the effects of prostaglandin E2 on airway tone.
American journal of physiology. Lung cellular and molecular physiology 2003;284(4):L599-606.
2002: MyTrang Nguyen; Michael Solle; Laurent P Audoly; Stephen L Tilley; Jeffrey L Stock; John McNeish; Thomas M Coffman; David Dombrowicz; Beverly H Koller
Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4586-93.
2002: Parimal Bhattacherjee; Partha Mukhopadhyay; Stephen L Tilley; Beverly H Koller; Thomas Geoghgan; Christopher A Paterson
Blood-aqueous barrier in prostaglandin EP2 receptor knockout mice.
Ocular immunology and inflammation 2002;10(3):187-96.
2001: Chandra Nataraj; Dennis W Thomas; Stephen L Tilley; M T Nguyen; Roslyn B Mannon; Beverly H Koller; Thomas M Coffman
Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse.
The Journal of clinical investigation 2001;108(8):1229-35.
2001: Stephen L Tilley; T M Coffman; Beverly H Koller
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes.
The Journal of clinical investigation 2001;108(1):15-23.
2001: Laurent P Audoly; X Ruan; V A Wagner; Jennifer L Goulet; Stephen L Tilley; Beverly H Koller; Thomas M Coffman; William J Arendshorst
Role of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H327-33.
2000: Christopher A Salvatore; Stephen L Tilley; Anne M Latour; Daniel S Fletcher; Beverly H Koller; Marlene A Jacobson
Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells.
The Journal of biological chemistry 2000;275(6):4429-34.
2000: Stephen L Tilley; V A Wagoner; Christopher A Salvatore; Marlene A Jacobson; Beverly H Koller
Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells.
The Journal of clinical investigation 2000;105(3):361-7.
1999: Laurent P Audoly; Stephen L Tilley; Jennifer L Goulet; Mikelle Key-Solle; MyTrang Nguyen; Jeffrey L Stock; John McNeish; Beverly H Koller; Thomas M Coffman
Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.
The American journal of physiology 1999;277(3 Pt 2):H924-30.
1999: Stephen L Tilley; Laurent P Audoly; E H Hicks; Hyung-Suk Kim; Patrick J Flannery; Thomas M Coffman; Beverly H Koller
Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor.
The Journal of clinical investigation 1999;103(11):1539-45.
1996: Stephen L Tilley; J Newman; A Thomas
Antiphospholipid and anticentromere antibodies occurring together in a patient with pulmonary hypertension.
Tennessee medicine : journal of the Tennessee Medical Association 1996;89(5):166, 168.