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Ben Tilly

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Christina H Lim; Alice G M Bot; Hugo R de Jonge; Ben C Tilly
Osmosignaling and volume regulation in intestinal epithelial cells.
Christina H Lim; Marcel J C Bijvelds; Alex L Nigg; Kees Schoonderwoerd; Adriaan B Houtsmuller; Hugo R de Jonge; Ben C Tilly
Cholesterol depletion and genistein as tools to promote F508delCFTR retention at the plasma membrane.
Christina H Lim; Kees Schoonderwoerd; W J Kleijer; Hugo R de Jonge; Ben C Tilly
Regulation of the cell swelling-activated chloride conductance by cholesterol-rich membrane domains.

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All Publications

2007: Christina H Lim; Alice G M Bot; Hugo R de Jonge; Ben C Tilly
Osmosignaling and volume regulation in intestinal epithelial cells.
Methods in enzymology 2007;428():325-42.
2007: Christina H Lim; Marcel J C Bijvelds; Alex L Nigg; Kees Schoonderwoerd; Adriaan B Houtsmuller; Hugo R de Jonge; Ben C Tilly
Cholesterol depletion and genistein as tools to promote F508delCFTR retention at the plasma membrane.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(5):473-82.
2006: Christina H Lim; Kees Schoonderwoerd; W J Kleijer; Hugo R de Jonge; Ben C Tilly
Regulation of the cell swelling-activated chloride conductance by cholesterol-rich membrane domains.
Acta physiologica (Oxford, England) 2006;187(1-2):295-303.
2004: Sebastian F B Tomassen; Durk Fekkes; Hugo R de Jonge; Ben C Tilly
Osmotic swelling-provoked release of organic osmolytes in human intestinal epithelial cells.
American journal of physiology. Cell physiology 2004;286(6):C1417-22.
2004: Sebastian F B Tomassen; Thea van der Wijk; Hugo R de Jonge; Ben C Tilly
Activation of phospholipase D by osmotic cell swelling.
FEBS letters 2004;566(1-3):287-90.
2004: Patrick Verloo; Clemens H M Kocken; Annemarie van der Wel; Ben C Tilly; Boris M Hogema; Maarten Sinaasappel; Alan Thomas; Hugo R de Jonge
Plasmodium falciparum-activated chloride channels are defective in erythrocytes from cystic fibrosis patients.
The Journal of biological chemistry 2004;279(11):10316-22.
2004: Sebastian Tomassen; Hugo R de Jonge; Ben C Tilly
Cell volume regulation in intestinal epithelial cells.
Advances in experimental medicine and biology 2004;559():339-47.
2003: Thea van der Wijk; Sebastian F B Tomassen; Adriaan B Houtsmuller; Hugo R de Jonge; Ben C Tilly
Increased vesicle recycling in response to osmotic cell swelling. Cause and consequence of hypotonicity-provoked ATP release.
The Journal of biological chemistry 2003;278(41):40020-5.
2002: Henriëtte W de Jonge; Dick H W Dekkers; Ben C Tilly; Jos M J Lamers
Cyclic stretch and endothelin-1 mediated activation of chloride channels in cultured neonatal rat ventricular myocytes.
Clinical science (London, England : 1979) 2002;103 Suppl 48():148S-151S.
2000: Hugo R de Jonge; Boris M Hogema; Ben C Tilly
Protein N-myristoylation: critical role in apoptosis and salt tolerance.
Science's STKE : signal transduction knowledge environment 2000;2000(63):pe1.
2000: Thea van der Wijk; Sebastian F B Tomassen; Hugo R de Jonge; Ben C Tilly
Signalling mechanisms involved in volume regulation of intestinal epithelial cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):289-96.
1999: Thea van der Wijk; Hugo R de Jonge; Ben C Tilly
Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels.
The Biochemical journal 1999;343 Pt 3():579-86.
1998: Thea van der Wijk; J Dorrestijn; S Narumiya; J Antonie Maassen; Hugo R de Jonge; Ben C Tilly
Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway.
The Biochemical journal 1998;331 ( Pt 3)():863-9.
1998: Arie B Vaandrager; Albert Smolenski; Ben C Tilly; Adriaan B Houtsmuller; E M Ehlert; Alice G M Bot; Marcel Edixhoven; W E Boomaars; Suzanne M Lohmann; Hugo R de Jonge
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1466-71.
1997: Arie B Vaandrager; Ben C Tilly; Albert Smolenski; S Schneider-Rasp; Alice G M Bot; Marcel Edixhoven; Bob J Scholte; Thomas Jarchau; Ulrich Walter; Suzanne M Lohmann; Wolfgang Poller; Hugo R de Jonge
cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta.
The Journal of biological chemistry 1997;272(7):4195-200.
1997: A Pietersma; Ben C Tilly; M Gaestel; N de Jong; J C Lee; JF Koster; Wim Sluiter
p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level.
Biochemical and biophysical research communications 1997;230(1):44-8.
1996: Ben C Tilly; M Gaestel; K Engel; Marcel Edixhoven; Hugo R de Jonge
Hypo-osmotic cell swelling activates the p38 MAP kinase signalling cascade.
FEBS letters 1996;395(2-3):133-6.
1996: Ben C Tilly; Marcel Edixhoven; Leon Tertoolen; N Morii; Y Saitoh; S Narumiya; Hugo R de Jonge
Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.
Molecular biology of the cell 1996;7(9):1419-27.
1996: Ben C Tilly; Karel Bezstarosti; W E Boomaars; C R Marino; Jos M J Lamers; Hugo R de Jonge
Expression and regulation of chloride channels in neonatal rat cardiomyocytes.
Molecular and cellular biochemistry 1996;157(1-2):129-35.
1994: Ben C Tilly; Marcel Edixhoven; N van den Berghe; Alice G M Bot; Hugo R de Jonge
Ca(2+)-mobilizing hormones potentiate hypotonicity-induced activation of ionic conductances in Intestine 407 cells.
The American journal of physiology 1994;267(5 Pt 1):C1271-8.
1993: Ben C Tilly; N van den Berghe; Leon Tertoolen; Marcel Edixhoven; Hugo R de Jonge
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.
The Journal of biological chemistry 1993;268(27):19919-22.
1992: Ben C Tilly; Grazia M S Mancini; Jan Bijman; Pieter van Gageldonk; Cecile E M T Beerens; R J Bridges; Hugo R de Jonge; Frans W Verheijen
Nucleotide-activated chloride channels in lysosomal membranes.
Biochemical and biophysical research communications 1992;187(1):254-60.
1991: Ben C Tilly; M Kansen; Pieter van Gageldonk; N van den Berghe; H Galjaard; Jan Bijman; Hugo R de Jonge
G-proteins mediate intestinal chloride channel activation.
The Journal of biological chemistry 1991;266(4):2036-40.
1991: Jan Bijman; Henk J Veeze; M Kansen; Ben C Tilly; Bob J Scholte; André Hoogeveen; D J J Halley; Maarten Sinaasappel; H de Jonge
Chloride transport in the cystic fibrosis enterocyte.
Advances in experimental medicine and biology 1991;290():287-94; discussion 294-6.
1990: Ben C Tilly; A C Lambrechts; Leon Tertoolen; SW De Laat; Wouter H Moolenaar
Regulation of phosphoinositide hydrolysis induced by histamine and guanine nucleotides in human HeLa carcinoma cells. Calcium and pH dependence and inhibitory role of protein kinase C.
FEBS letters 1990;265(1-2):80-4.
1990: Ben C Tilly; Leon Tertoolen; R Remorie; A Ladoux; I Verlaan; SW De Laat; Wouter H Moolenaar
Histamine as a growth factor and chemoattractant for human carcinoma and melanoma cells: action through Ca2(+)-mobilizing H1 receptors.
The Journal of cell biology 1990;110(4):1211-5.
1990: Ben C Tilly; Leon Tertoolen; A C Lambrechts; R Remorie; SW De Laat; Wouter H Moolenaar
Histamine-H1-receptor-mediated phosphoinositide hydrolysis, Ca2+ signalling and membrane-potential oscillations in human HeLa carcinoma cells.
The Biochemical journal 1990;266(1):235-43.
1990: Ben C Tilly; M Kansen; Pieter van Gageldonk; N van den Berghe; Jan Bijman; Hugo R de Jonge
Activation of intestinal chloride channels by GTP-binding regulatory proteins.
Advances in second messenger and phosphoprotein research 1990;24():95-100.
1989: Libert H K Defize; Johannes Boonstra; J Meisenhelder; Wiebe Kruijer; Leon Tertoolen; Ben C Tilly; Tony Hunter; Paul M P van Bergen en Henegouwen; Wouter H Moolenaar; SW De Laat
Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors.
The Journal of cell biology 1989;109(5):2495-507.
1989: Hugo R de Jonge; N van den Berghe; Ben C Tilly; M Kansen; Jan Bijman
(Dys)regulation of epithelial chloride channels.
Biochemical Society transactions 1989;17(5):816-8.
1988: Ben C Tilly; P A van Paridon; I Verlaan; SW De Laat; Wouter H Moolenaar
Epidermal-growth-factor-induced formation of inositol phosphates in human A431 cells. Differences from the effect of bradykinin.
The Biochemical journal 1988;252(3):857-63.
1988: Wouter H Moolenaar; A J Bierman; Ben C Tilly; I Verlaan; Libert H K Defize; A M Honegger; A Ullrich; J Schlessinger
A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction.
The EMBO journal 1988;7(3):707-10.
1987: Ben C Tilly; P A van Paridon; I Verlaan; Karel Wirtz; SW De Laat; Wouter H Moolenaar
Inositol phosphate metabolism in bradykinin-stimulated human A431 carcinoma cells. Relationship to calcium signalling.
The Biochemical journal 1987;244(1):129-35.
1987: Leon Tertoolen; Ben C Tilly; R F Irvine; Wouter H Moolenaar
Electrophysiological responses to bradykinin and microinjected inositol polyphosphates in neuroblastoma cells. Possible role of inositol 1,3,4-trisphosphate in altering membrane potential.
FEBS letters 1987;214(2):365-9.
1986: Wouter H Moolenaar; Wiebe Kruijer; Ben C Tilly; I Verlaan; A J Bierman; SW De Laat
Growth factor-like action of phosphatidic acid.
Nature 1986;323(6084):171-3.
1986: Wouter H Moolenaar; Libert H K Defize; Ben C Tilly; A J Bierman; SW De Laat
Transmembrane signalling by growth factors.
Annals of the New York Academy of Sciences 1986;488():491-502.