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Rupert Timpl

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

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Piscaglia Fabio; Dudás József; Knittel Thomas; Di Rocco Paola; Kobold Dominik; Saile Bernhard; Zocco Maria Assunta; Timpl Rupert; Ramadori Giuliano
Expression of ECM proteins fibulin-1 and -2 in acute and chronic liver disease and in cultured rat liver cells.
Giudici Camilla; Raynal Nicolas; Wiedemann Hanna; Cabral Wayne A; Marini Joan C; Timpl Rupert; Bächinger Hans Peter; Farndale Richard W; Sasaki Takako; Tenni Ruggero
Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens.
Kabosova Andrea; Azar Dimitri T; Bannikov Gregory A; Campbell Kevin P; Durbeej Madeleine; Ghohestani Reza F; Jones Jonathan C R; Kenney M Cristina; Koch Manuel; Ninomiya Yoshifumi; Patton Bruce L; Paulsson Mats; Sado Yoshikazu; Sage E Helene; Sasaki Takako; Sorokin Lydia M; Steiner-Champliaud Marie-France; Sun Tung-Tien; Sundarraj Nirmala; Timpl Rupert; Virtanen Ismo; Ljubimov Alexander V
Compositional differences between infant and adult human corneal basement membranes.

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All Publications

2009: Piscaglia Fabio; Dudás József; Knittel Thomas; Di Rocco Paola; Kobold Dominik; Saile Bernhard; Zocco Maria Assunta; Timpl Rupert; Ramadori Giuliano
Expression of ECM proteins fibulin-1 and -2 in acute and chronic liver disease and in cultured rat liver cells.
Cell and tissue research 2009;337(3):449-62.
2008: Giudici Camilla; Raynal Nicolas; Wiedemann Hanna; Cabral Wayne A; Marini Joan C; Timpl Rupert; Bächinger Hans Peter; Farndale Richard W; Sasaki Takako; Tenni Ruggero
Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens.
The Journal of biological chemistry 2008;283(28):19551-60.
2007: Kabosova Andrea; Azar Dimitri T; Bannikov Gregory A; Campbell Kevin P; Durbeej Madeleine; Ghohestani Reza F; Jones Jonathan C R; Kenney M Cristina; Koch Manuel; Ninomiya Yoshifumi; Patton Bruce L; Paulsson Mats; Sado Yoshikazu; Sage E Helene; Sasaki Takako; Sorokin Lydia M; Steiner-Champliaud Marie-France; Sun Tung-Tien; Sundarraj Nirmala; Timpl Rupert; Virtanen Ismo; Ljubimov Alexander V
Compositional differences between infant and adult human corneal basement membranes.
Investigative ophthalmology & visual science 2007;48(11):4989-99.
2007: Kobayashi Naoyuki; Kostka Günter; Garbe Jörg H O; Keene Douglas R; Bächinger Hans Peter; Hanisch Franz-Georg; Markova Dessislava; Tsuda Takeshi; Timpl Rupert; Chu Mon-Li; Sasaki Takako
A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization.
The Journal of biological chemistry 2007;282(16):11805-16.
2006: Kvist Alexander J; Johnson Anna E; Mörgelin Matthias; Gustafsson Erika; Bengtsson Eva; Lindblom Karin; Aszódi Attila; Fässler Reinhard; Sasaki Takako; Timpl Rupert; Aspberg Anders
Chondroitin sulfate perlecan enhances collagen fibril formation. Implications for perlecan chondrodysplasias.
The Journal of biological chemistry 2006;281(44):33127-39.
2006: Schmidt Annette; Wenzel Daniela; Thorey Irmgard; Sasaki Takako; Hescheler Jürgen; Timpl Rupert; Addicks Klaus; Werner Sabine; Fleischmann Bernd K; Bloch Wilhelm
Endostatin influences endothelial morphology via the activated ERK1/2-kinase endothelial morphology and signal transduction.
Microvascular research 2006;71(3):152-62.
2006: Allen Justin M; Bateman John F; Hansen Uwe; Wilson Richard; Bruckner Peter; Owens Rick T; Sasaki Takako; Timpl Rupert; Fitzgerald Jamie
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan.
The Journal of biological chemistry 2006;281(11):7341-9.
2006: Sasaki Takako; Knyazev Pjotr G; Clout Naomi J; Cheburkin Yuri; Göhring Walter; Ullrich Axel; Timpl Rupert; Hohenester Erhard
Structural basis for Gas6-Axl signalling.
The EMBO journal 2006;25(1):80-7.
2005: Kanagawa Motoi; Michele Daniel E; Satz Jakob S; Barresi Rita; Kusano Hajime; Sasaki Takako; Timpl Rupert; Henry Michael D; Campbell Kevin P
Disruption of perlecan binding and matrix assembly by post-translational or genetic disruption of dystroglycan function.
FEBS letters 2005;579(21):4792-6.
2005: Gersdorff Nikolaus; Kohfeldt Eddie; Sasaki Takako; Timpl Rupert; Miosge Nicolai
Laminin gamma3 chain binds to nidogen and is located in murine basement membranes.
The Journal of biological chemistry 2005;280(23):22146-53.
2005: Tiedemann Kerstin; Sasaki Takako; Gustafsson Erika; Göhring Walter; Bätge Boris; Notbohm Holger; Timpl Rupert; Wedel Thilo; Schlötzer-Schrehardt Ursula; Reinhardt Dieter P
Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.
The Journal of biological chemistry 2005;280(12):11404-12.
2005: Schéele Susanne; Falk Mats; Franzén Ahnders; Ellin Fredrik; Ferletta Maria; Lonai Peter; Andersson Björn; Timpl Rupert; Forsberg Erik; Ekblom Peter
Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1502-6.
2004: Olsson Anna-Karin; Johansson Irja; Akerud Helena; Einarsson Barbro; Christofferson Rolf; Sasaki Takako; Timpl Rupert; Claesson-Welsh Lena
The minimal active domain of endostatin is a heparin-binding motif that mediates inhibition of tumor vascularization.
Cancer research 2004;64(24):9012-7.
2004: Schmidt Annette; Wenzel Daniela; Ferring Isabell; Kazemi Shohreh; Sasaki Takako; Hescheler Jürgen; Timpl Rupert; Addicks Klaus; Fleischmann Bernd K; Bloch Wilhelm
Influence of endostatin on embryonic vasculo- and angiogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;230(3):468-80.
2004: Day Joanna M; Olin Anders I; Murdoch Alan D; Canfield Ann; Sasaki Takako; Timpl Rupert; Hardingham Timothy E; Aspberg Anders
Alternative splicing in the aggrecan G3 domain influences binding interactions with tenascin-C and other extracellular matrix proteins.
The Journal of biological chemistry 2004;279(13):12511-8.
2003: Meng Xianmin; Klement John F; Leperi Dominic A; Birk David E; Sasaki Takako; Timpl Rupert; Uitto Jouni; Pulkkinen Leena
Targeted inactivation of murine laminin gamma2-chain gene recapitulates human junctional epidermolysis bullosa.
The Journal of investigative dermatology 2003;121(4):720-31.
2003: Grabski Robert; Szul Tomasz; Sasaki Takako; Timpl Rupert; Mayne Richard; Hicks Barrett; Sztul Elizabeth
Mutations in COCH that result in non-syndromic autosomal dominant deafness (DFNA9) affect matrix deposition of cochlin.
Human genetics 2003;113(5):406-16.
2003: Wizemann Harald; Garbe Jörg H O; Friedrich Martin V K; Timpl Rupert; Sasaki Takako; Hohenester Erhard
Distinct requirements for heparin and alpha-dystroglycan binding revealed by structure-based mutagenesis of the laminin alpha2 LG4-LG5 domain pair.
Journal of molecular biology 2003;332(3):635-42.
2003: Timpl Rupert; Sasaki Takako; Kostka Günter; Chu Mon-Li
Fibulins: a versatile family of extracellular matrix proteins.
Nature reviews. Molecular cell biology 2003;4(6):479-89.
2003: Ferletta Maria; Kikkawa Yamato; Yu Hao; Talts Jan F; Durbeej Madeleine; Sonnenberg Arnoud; Timpl Rupert; Campbell Kevin P; Ekblom Peter; Genersch Elke
Opposing roles of integrin alpha6Abeta1 and dystroglycan in laminin-mediated extracellular signal-regulated kinase activation.
Molecular biology of the cell 2003;14(5):2088-103.
2003: Markova Dessislava; Zou Yaqun; Ringpfeil Franziska; Sasaki Takako; Kostka Günter; Timpl Rupert; Uitto Jouni; Chu Mon-Li
Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene.
American journal of human genetics 2003;72(4):998-1004.
2003: Ahrens Thomas; Lambert Mireille; Pertz Olivier; Sasaki Takako; Schulthess Therese; Mège René-Marc; Timpl Rupert; Engel Jürgen
Homoassociation of VE-cadherin follows a mechanism common to "classical" cadherins.
Journal of molecular biology 2003;325(4):733-42.
2002: Kreuger Johan; Matsumoto Taro; Vanwildemeersch Maarten; Sasaki Takako; Timpl Rupert; Claesson-Welsh Lena; Spillmann Dorothe; Lindahl Ulf
Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function.
The EMBO journal 2002;21(23):6303-11.
2002: Wiberg Charlotte; Heinegård Dick; Wenglén Christina; Timpl Rupert; Mörgelin Matthias
Biglycan organizes collagen VI into hexagonal-like networks resembling tissue structures.
The Journal of biological chemistry 2002;277(51):49120-6.
2002: Miosge Nicolai; Sasaki Takako; Timpl Rupert
Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice.
Matrix biology : journal of the International Society for Matrix Biology 2002;21(7):611-21.
2002: Sasaki Takako; Knyazev Pjotr G; Cheburkin Yuri; Göhring Walter; Tisi Dominic; Ullrich Axel; Timpl Rupert; Hohenester Erhard
Crystal structure of a C-terminal fragment of growth arrest-specific protein Gas6. Receptor tyrosine kinase activation by laminin G-like domains.
The Journal of biological chemistry 2002;277(46):44164-70.
2002: Salmivirta Katriina; Talts Jan F; Olsson Magnus; Sasaki Takako; Timpl Rupert; Ekblom Peter
Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.
Experimental cell research 2002;279(2):188-201.
2002: Schymeinsky Jürgen; Nedbal Sabine; Miosge Nicolai; Pöschl Ernst; Rao Cherie; Beier David R; Skarnes William C; Timpl Rupert; Bader Bernhard L
Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice.
Molecular and cellular biology 2002;22(19):6820-30.
2002: Rattenholl Anke; Pappano William N; Koch Manuel; Keene Douglas R; Kadler Karl E; Sasaki Takako; Timpl Rupert; Burgeson Robert E; Greenspan Daniel S; Bruckner-Tuderman Leena
Proteinases of the bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen.
The Journal of biological chemistry 2002;277(29):26372-8.
2002: Willem Michael; Miosge Nicolai; Halfter Willi; Smyth Neil; Jannetti Iris; Burghart Elke; Timpl Rupert; Mayer Ulrike
Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.
Development (Cambridge, England) 2002;129(11):2711-22.
2002: Tu Hongmin; Sasaki Takako; Snellman Anne; Göhring Walter; Pirilä Paivi; Timpl Rupert; Pihlajaniemi Taina
The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.
The Journal of biological chemistry 2002;277(25):23092-9.
2002: Than Manuel E; Henrich Stefan; Huber Robert; Ries Albert; Mann Karlheinz; Kühn Klaus; Timpl Rupert; Bourenkov Gleb P; Bartunik Hans D; Bode Wolfram
The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6607-12.
2002: Sasaki Takako; Giltay Richard; Talts Ulrika; Timpl Rupert; Talts Jan F
Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.
Experimental cell research 2002;275(2):185-99.
2002: Hellstern Simon; Sasaki Takako; Fauser Charlotte; Lustig Ariel; Timpl Rupert; Engel Jürgen
Functional studies on recombinant domains of Mac-2-binding protein.
The Journal of biological chemistry 2002;277(18):15690-6.
2002: Dixelius Johan; Cross Michael; Matsumoto Taro; Sasaki Takako; Timpl Rupert; Claesson-Welsh Lena
Endostatin regulates endothelial cell adhesion and cytoskeletal organization.
Cancer research 2002;62(7):1944-7.
2002: Bengtsson Eva; Mörgelin Matthias; Sasaki Takako; Timpl Rupert; Heinegård Dick; Aspberg Anders
The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor.
The Journal of biological chemistry 2002;277(17):15061-8.
2002: Doi Masayuki; Thyboll Jill; Kortesmaa Jarkko; Jansson Katarina; Iivanainen Antti; Parvardeh Masomeh; Timpl Rupert; Hedin Ulf; Swedenborg Jesper; Tryggvason Karl
Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells.
The Journal of biological chemistry 2002;277(15):12741-8.
2002: Sasaki Takako; Hohenester Erhard; Timpl Rupert
Structure and function of collagen-derived endostatin inhibitors of angiogenesis.
IUBMB life 2002;53(2):77-84.
2002: Tunggal Lucy; Ravaux Juliette; Pesch Monika; Smola Hans; Krieg Thomas; Gaill Françoise; Sasaki Takako; Timpl Rupert; Mauch Cornelia; Aumailley Monique
Defective laminin 5 processing in cylindroma cells.
The American journal of pathology 2002;160(2):459-68.
2002: Garbe Jörg H O; Göhring Walter; Mann Karlheinz; Timpl Rupert; Sasaki Takako
Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.
The Biochemical journal 2002;362(Pt 1):213-21.
2002: Sasaki Takako; Mann Karlheinz; Miner Jeffrey H; Miosge Nicolai; Timpl Rupert
Domain IV of mouse laminin beta1 and beta2 chains.
European journal of biochemistry / FEBS 2002;269(2):431-42.
2002: Sorensen Dag R; Read Tracy-Ann; Porwol Torsten; Olsen Bjorn Reino; Timpl Rupert; Sasaki Takako; Iversen Per O; Benestad Haakon B; Sim B Kim Lee; Bjerkvig Rolf
Endostatin reduces vascularization, blood flow, and growth in a rat gliosarcoma.
Neuro-oncology 2002;4(1):1-8.
2002: French Margaret M; Gomes Ronald R; Timpl Rupert; Höök Magnus; Czymmek Kirk; Farach-Carson Mary C; Carson Daniel D
Chondrogenic activity of the heparan sulfate proteoglycan perlecan maps to the N-terminal domain I.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(1):48-55.
2001: Sasaki T; Timpl R
Domain IVa of laminin alpha5 chain is cell-adhesive and binds beta1 and alphaVbeta3 integrins through Arg-Gly-Asp.
FEBS letters 2001;509(2):181-5.
2001: Sasaki T; Göhring W; Mann K; Brakebusch C; Yamada Y; Fässler R; Timpl R
Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins.
Journal of molecular biology 2001;314(4):751-63.
2001: Ries A; Göhring W; Fox J W; Timpl R; Sasaki T
Recombinant domains of mouse nidogen-1 and their binding to basement membrane proteins and monoclonal antibodies.
European journal of biochemistry / FEBS 2001;268(19):5119-28.
2001: Kvansakul M; Hopf M; Ries A; Timpl R; Hohenester E
Structural basis for the high-affinity interaction of nidogen-1 with immunoglobulin-like domain 3 of perlecan.
The EMBO journal 2001;20(19):5342-6.
2001: Kostka G; Giltay R; Bloch W; Addicks K; Timpl R; Fässler R; Chu M L
Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice.
Molecular and cellular biology 2001;21(20):7025-34.
2001: Gu Y C; Talts J F; Gullberg D; Timpl R; Ekblom M
Glucocorticoids down-regulate the extracellular matrix proteins fibronectin, fibulin-1 and fibulin-2 in bone marrow stroma.
European journal of haematology 2001;67(3):176-84.
2001: Sasaki T; Mann K; Timpl R
Modification of the laminin alpha 4 chain by chondroitin sulfate attachment to its N-terminal domain.
FEBS letters 2001;505(1):173-8.
2001: Tsuda T; Wang H; Timpl R; Chu M L
Fibulin-2 expression marks transformed mesenchymal cells in developing cardiac valves, aortic arch vessels, and coronary vessels.
Developmental dynamics : an official publication of the American Association of Anatomists 2001;222(1):89-100.
2001: Hopf M; Göhring W; Mann K; Timpl R
Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.
Journal of molecular biology 2001;311(3):529-41.
2001: Hopf M; Göhring W; Ries A; Timpl R; Hohenester E
Crystal structure and mutational analysis of a perlecan-binding fragment of nidogen-1.
Nature structural biology 2001;8(7):634-40.
2001: Wiberg C; Hedbom E; Khairullina A; Lamandé S R; Oldberg A; Timpl R; Mörgelin M; Heinegård D
Biglycan and decorin bind close to the n-terminal region of the collagen VI triple helix.
The Journal of biological chemistry 2001;276(22):18947-52.
2001: Read T A; Sorensen D R; Mahesparan R; Enger P O; Timpl R; Olsen B R; Hjelstuen M H; Haraldseth O; Bjerkvig R
Local endostatin treatment of gliomas administered by microencapsulated producer cells.
Nature biotechnology 2001;19(1):29-34.
2001: Olin A I; Mörgelin M; Sasaki T; Timpl R; Heinegård D; Aspberg A
The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding.
The Journal of biological chemistry 2001;276(2):1253-61.
2000: Bloch W; Huggel K; Sasaki T; Grose R; Bugnon P; Addicks K; Timpl R; Werner S
The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(15):2373-6.
2000: Talts J F; Sasaki T; Miosge N; Göhring W; Mann K; Mayne R; Timpl R
Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues.
The Journal of biological chemistry 2000;275(45):35192-9.
2000: Sasaki T; Larsson H; Tisi D; Claesson-Welsh L; Hohenester E; Timpl R
Endostatins derived from collagens XV and XVIII differ in structural and binding properties, tissue distribution and anti-angiogenic activity.
Journal of molecular biology 2000;301(5):1179-90.
2000: Timpl R; Tisi D; Talts J F; Andac Z; Sasaki T; Hohenester E
Structure and function of laminin LG modules.
Matrix biology : journal of the International Society for Matrix Biology 2000;19(4):309-17.
2000: Brakebusch C; Grose R; Quondamatteo F; Ramirez A; Jorcano J L; Pirro A; Svensson M; Herken R; Sasaki T; Timpl R; Werner S; Fässler R
Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes.
The EMBO journal 2000;19(15):3990-4003.
2000: Busch E; Hohenester E; Timpl R; Paulsson M; Maurer P
Calcium affinity, cooperativity, and domain interactions of extracellular EF-hands present in BM-40.
The Journal of biological chemistry 2000;275(33):25508-15.
2000: Dixelius J; Larsson H; Sasaki T; Holmqvist K; Lu L; Engström A; Timpl R; Welsh M; Claesson-Welsh L
Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis.
Blood 2000;95(11):3403-11.
2000: Friedrich M V; Schneider M; Timpl R; Baumgartner S
Perlecan domain V of Drosophila melanogaster. Sequence, recombinant analysis and tissue expression.
European journal of biochemistry / FEBS 2000;267(11):3149-59.
2000: Tisi D; Talts J F; Timpl R; Hohenester E
Structure of the C-terminal laminin G-like domain pair of the laminin alpha2 chain harbouring binding sites for alpha-dystroglycan and heparin.
The EMBO journal 2000;19(7):1432-40.
2000: Sasaki T; Hohenester E; Zhang R Z; Gotta S; Speer M C; Tandan R; Timpl R; Chu M L
A Bethlem myopathy Gly to Glu mutation in the von Willebrand factor A domain N2 of the collagen alpha3(VI) chain interferes with protein folding.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(5):761-8.
2000: Hohenester E; Sasaki T; Mann K; Timpl R
Variable zinc coordination in endostatin.
Journal of molecular biology 2000;297(1):1-6.
1999: Hohenester E; Tisi D; Talts J F; Timpl R
The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrin.
Molecular cell 1999;4(5):783-92.
1999: Costell M; Gustafsson E; Aszódi A; Mörgelin M; Bloch W; Hunziker E; Addicks K; Timpl R; Fässler R
Perlecan maintains the integrity of cartilage and some basement membranes.
The Journal of cell biology 1999;147(5):1109-22.
1999: Sasaki T; Larsson H; Kreuger J; Salmivirta M; Claesson-Welsh L; Lindahl U; Hohenester E; Timpl R
Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin.
The EMBO journal 1999;18(22):6240-8.
1999: Friedrich M V; Göhring W; Mörgelin M; Brancaccio A; David G; Timpl R
Structural basis of glycosaminoglycan modification and of heterotypic interactions of perlecan domain V.
Journal of molecular biology 1999;294(1):259-70.
1999: Sasaki T; Miosge N; Timpl R
Immunochemical and tissue analysis of protease generated neoepitopes of BM-40 (osteonectin, SPARC) which are correlated to a higher affinity binding to collagens.
Matrix biology : journal of the International Society for Matrix Biology 1999;18(5):499-508.
1999: Giltay R; Timpl R; Kostka G
Sequence, recombinant expression and tissue localization of two novel extracellular matrix proteins, fibulin-3 and fibulin-4.
Matrix biology : journal of the International Society for Matrix Biology 1999;18(5):469-80.
1999: Sasaki T; Göhring W; Miosge N; Abrams W R; Rosenbloom J; Timpl R
Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins.
FEBS letters 1999;460(2):280-4.
1999: Talts J F; Timpl R
Mutation of a basic sequence in the laminin alpha2LG3 module leads to a lack of proteolytic processing and has different effects on beta1 integrin-mediated cell adhesion and alpha-dystroglycan binding.
FEBS letters 1999;458(3):319-23.
1999: Müller S A; Sasaki T; Bork P; Wolpensinger B; Schulthess T; Timpl R; Engel A; Engel J
Domain organization of Mac-2 binding protein and its oligomerization to linear and ring-like structures.
Journal of molecular biology 1999;291(4):801-13.
1999: Pihlajamaa T; Perälä M; Vuoristo M M; Nokelainen M; Bodo M; Schulthess T; Vuorio E; Timpl R; Engel J; Ala-Kokko L
Characterization of recombinant human type IX collagen. Association of alpha chains into homotrimeric and heterotrimeric molecules.
The Journal of biological chemistry 1999;274(32):22464-8.
1999: Aspberg A; Adam S; Kostka G; Timpl R; Heinegård D
Fibulin-1 is a ligand for the C-type lectin domains of aggrecan and versican.
The Journal of biological chemistry 1999;274(29):20444-9.
1999: Andac Z; Sasaki T; Mann K; Brancaccio A; Deutzmann R; Timpl R
Analysis of heparin, alpha-dystroglycan and sulfatide binding to the G domain of the laminin alpha1 chain by site-directed mutagenesis.
Journal of molecular biology 1999;287(2):253-64.
1999: Hopf M; Göhring W; Kohfeldt E; Yamada Y; Timpl R
Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin.
European journal of biochemistry / FEBS 1999;259(3):917-25.
1999: Pan T C; Kostka G; Zhang R Z; Timpl R; Chu M L
Complete exon-intron organization of the mouse fibulin-1 gene and its comparison with the human fibulin-1 gene.
FEBS letters 1999;444(1):38-42.
1999: Talts J F; Andac Z; Göhring W; Brancaccio A; Timpl R
Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.
The EMBO journal 1999;18(4):863-70.
1999: Raghunath M; Tschödrich-Rotter M; Sasaki T; Meuli M; Chu M L; Timpl R
Confocal laser scanning analysis of the association of fibulin-2 with fibrillin-1 and fibronectin define different stages of skin regeneration.
The Journal of investigative dermatology 1999;112(1):97-101.
1998: Mayer U; Kohfeldt E; Timpl R
Structural and genetic analysis of laminin-nidogen interaction.
Annals of the New York Academy of Sciences 1998;857():130-42.
1998: Grässel S; Tan E M; Timpl R; Chu M L
Collagen type XVI expression is modulated by basic fibroblast growth factor and transforming growth factor-beta.
FEBS letters 1998;436(2):197-201.
1998: Sasaki T; Costell M; Mann K; Timpl R
Inhibition of glycosaminoglycan modification of perlecan domain I by site-directed mutagenesis changes protease sensitivity and laminin-1 binding activity.
FEBS letters 1998;435(2-3):169-72.
1998: Kohfeldt E; Sasaki T; Göhring W; Timpl R
Nidogen-2: a new basement membrane protein with diverse binding properties.
Journal of molecular biology 1998;282(1):99-109.
1998: Sasaki T; Fukai N; Mann K; Göhring W; Olsen B R; Timpl R
Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin.
The EMBO journal 1998;17(15):4249-56.
1998: Göhring W; Sasaki T; Heldin C H; Timpl R
Mapping of the binding of platelet-derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope.
European journal of biochemistry / FEBS 1998;255(1):60-6.
1998: Ettner N; Göhring W; Sasaki T; Mann K; Timpl R
The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan.
FEBS letters 1998;430(3):217-21.
1998: Talts J F; Mann K; Yamada Y; Timpl R
Structural analysis and proteolytic processing of recombinant G domain of mouse laminin alpha2 chain.
FEBS letters 1998;426(1):71-6.
1998: Lamandé S R; Sigalas E; Pan T C; Chu M L; Dziadek M; Timpl R; Bateman J F
The role of the alpha3(VI) chain in collagen VI assembly. Expression of an alpha3(VI) chain lacking N-terminal modules N10-N7 restores collagen VI assembly, secretion, and matrix deposition in an alpha3(VI)-deficient cell line.
The Journal of biological chemistry 1998;273(13):7423-30.
1998: Sasaki T; Hohenester E; Göhring W; Timpl R
Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin.
The EMBO journal 1998;17(6):1625-34.
1998: Sasaki T; Forsberg E; Bloch W; Addicks K; Fässler R; Timpl R
Deficiency of beta 1 integrins in teratoma interferes with basement membrane assembly and laminin-1 expression.
Experimental cell research 1998;238(1):70-81.
1997: Brown J C; Sasaki T; Göhring W; Yamada Y; Timpl R
The C-terminal domain V of perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycans.
European journal of biochemistry / FEBS 1997;250(1):39-46.
1997: Kohfeldt E; Maurer P; Vannahme C; Timpl R
Properties of the extracellular calcium binding module of the proteoglycan testican.
FEBS letters 1997;414(3):557-61.
1997: Adam S; Göhring W; Wiedemann H; Chu M L; Timpl R; Kostka G
Binding of fibulin-1 to nidogen depends on its C-terminal globular domain and a specific array of calcium-binding epidermal growth factor-like (EG) modules.
Journal of molecular biology 1997;272(2):226-36.
1997: Maurer P; Sasaki T; Mann K; Göhring W; Schwarzbauer J E; Timpl R
Structural and functional characterization of the extracellular calcium-binding protein BM-40/secreted protein, acidic, rich in cysteine/osteonectin from the nematode Caenorhabditis elegans.
European journal of biochemistry / FEBS 1997;248(1):209-16.
1997: Giltay R; Kostka G; Timpl R
Sequence and expression of a novel member (LTBP-4) of the family of latent transforming growth factor-beta binding proteins.
FEBS letters 1997;411(2-3):164-8.
1997: Sasaki T; Mann K; Wiedemann H; Göhring W; Lustig A; Engel J; Chu M L; Timpl R
Dimer model for the microfibrillar protein fibulin-2 and identification of the connecting disulfide bridge.
The EMBO journal 1997;16(11):3035-43.
1997: Mayer U; Mann K; Fessler L I; Fessler J H; Timpl R
Drosophila laminin binds to mammalian nidogen and to heparan sulfate proteoglycan.
European journal of biochemistry / FEBS 1997;245(3):745-50.
1997: Maurer P; Göhring W; Sasaki T; Mann K; Timpl R; Nischt R
Recombinant and tissue-derived mouse BM-40 bind to several collagen types and have increased affinities after proteolytic activation.
Cellular and molecular life sciences : CMLS 1997;53(5):478-84.
1997: Sasaki T; Göhring W; Mann K; Maurer P; Hohenester E; Knäuper V; Murphy G; Timpl R
Limited cleavage of extracellular matrix protein BM-40 by matrix metalloproteinases increases its affinity for collagens.
The Journal of biological chemistry 1997;272(14):9237-43.
1997: Kadoya Y; Salmivirta K; Talts J F; Kadoya K; Mayer U; Timpl R; Ekblom P
Importance of nidogen binding to laminin gamma1 for branching epithelial morphogenesis of the submandibular gland.
Development (Cambridge, England) 1997;124(3):683-91.
1997: Costell M; Mann K; Yamada Y; Timpl R
Characterization of recombinant perlecan domain I and its substitution by glycosaminoglycans and oligosaccharides.
European journal of biochemistry / FEBS 1997;243(1-2):115-21.
1996: Durbeej M; Fecker L; Hjalt T; Zhang H Y; Salmivirta K; Klein G; Timpl R; Sorokin L; Ebendal T; Ekblom P; Ekblom M
Expression of laminin alpha 1, alpha 5 and beta 2 chains during embryogenesis of the kidney and vasculature.
Matrix biology : journal of the International Society for Matrix Biology 1996;15(6):397-413.
1996: Grässel S; Timpl R; Tan E M; Chu M L
Biosynthesis and processing of type XVI collagen in human fibroblasts and smooth muscle cells.
European journal of biochemistry / FEBS 1996;242(3):576-84.
1996: Sasaki T; Wiedemann H; Matzner M; Chu M L; Timpl R
Expression of fibulin-2 by fibroblasts and deposition with fibronectin into a fibrillar matrix.
Journal of cell science 1996;109 ( Pt 12)():2895-904.
1996: Costell M; Sasaki T; Mann K; Yamada Y; Timpl R
Structural characterization of recombinant domain II of the basement membrane proteoglycan perlecan.
FEBS letters 1996;396(2-3):127-31.
1996: Sasaki T; Mann K; Murphy G; Chu M L; Timpl R
Different susceptibilities of fibulin-1 and fibulin-2 to cleavage by matrix metalloproteinases and other tissue proteases.
European journal of biochemistry / FEBS 1996;240(2):427-34.
1996: Dziadek M; Darling P; Bakker M; Overall M; Zhang R Z; Pan T C; Tillet E; Timpl R; Chu M L
Deposition of collagen VI in the extracellular matrix during mouse embryogenesis correlates with expression of the alpha 3(VI) subunit gene.
Experimental cell research 1996;226(2):302-15.
1996: Mann K; Mechling D E; Bächinger H P; Eckerskorn C; Gaill F; Timpl R
Glycosylated threonine but not 4-hydroxyproline dominates the triple helix stabilizing positions in the sequence of a hydrothermal vent worm cuticle collagen.
Journal of molecular biology 1996;261(2):255-66.
1996: Kohfeldt E; Göhring W; Mayer U; Zweckstetter M; Holak T A; Chu M L; Timpl R
Conversion of the Kunitz-type module of collagen VI into a highly active trypsin inhibitor by site-directed mutagenesis.
European journal of biochemistry / FEBS 1996;238(2):333-40.
1996: Baumgartner R; Czisch M; Mayer U; Pöschl E; Huber R; Timpl R; Holak T A
Structure of the nidogen binding LE module of the laminin gamma1 chain in solution.
Journal of molecular biology 1996;257(3):658-68.
1996: Stetefeld J; Mayer U; Timpl R; Huber R
Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) modules of laminin gamma1 chain harboring the nidogen binding site.
Journal of molecular biology 1996;257(3):644-57.
1996: Pfaff M; Reinhardt D P; Sakai L Y; Timpl R
Cell adhesion and integrin binding to recombinant human fibrillin-1.
FEBS letters 1996;384(3):247-50.
1996: Schulze B; Mann K; Poschl E; Yamada Y; Timpl R
Structural and functional analysis of the globular domain IVa of the laminin alpha 1 chain and its impact on an adjacent RGD site.
The Biochemical journal 1996;314 ( Pt 3)():847-51.
1996: Zweckstetter M; Czisch M; Mayer U; Chu M L; Zinth W; Timpl R; Holak T A
Structure and multiple conformations of the kunitz-type domain from human type VI collagen alpha3(VI) chain in solution.
Structure (London, England : 1993) 1996;4(2):195-209.
1996: Fässler R; Sasaki T; Timpl R; Chu M L; Werner S
Differential regulation of fibulin, tenascin-C, and nidogen expression during wound healing of normal and glucocorticoid-treated mice.
Experimental cell research 1996;222(1):111-6.
1996: Hohenester E; Maurer P; Hohenadl C; Timpl R; Jansonius J N; Engel J
Structure of a novel extracellular Ca(2+)-binding module in BM-40.
Nature structural biology 1996;3(1):67-73.
1995: Sasaki T; Göhring W; Pan T C; Chu M L; Timpl R
Binding of mouse and human fibulin-2 to extracellular matrix ligands.
Journal of molecular biology 1995;254(5):892-9.
1995: Maurer P; Hohenadl C; Hohenester E; Göhring W; Timpl R; Engel J
The C-terminal portion of BM-40 (SPARC/osteonectin) is an autonomously folding and crystallisable domain that binds calcium and collagen IV.
Journal of molecular biology 1995;253(2):347-57.
1995: Hohenadl C; Mann K; Mayer U; Timpl R; Paulsson M; Aeschlimann D
Two adjacent N-terminal glutamines of BM-40 (osteonectin, SPARC) act as amine acceptor sites in transglutaminaseC-catalyzed modification.
The Journal of biological chemistry 1995;270(40):23415-20.
1995: Schulze B; Mann K; Battistutta R; Wiedemann H; Timpl R
Structural properties of recombinant domain III-3 of perlecan containing a globular domain inserted into an epidermal-growth-factor-like motif.
European journal of biochemistry / FEBS 1995;231(3):551-6.
1995: Auerbach G; Gaill F; Jaenicke R; Schulthess T; Timpl R; Engel J
Pressure dependence of collagen melting.
Matrix biology : journal of the International Society for Matrix Biology 1995;14(7):589-92.
1995: Pfaff M; Sasaki T; Tangemann K; Chu M L; Timpl R
Integrin-binding and cell-adhesion studies of fibulins reveal a particular affinity for alpha IIb beta 3.
Experimental cell research 1995;219(1):87-92.
1995: Specks U; Nerlich A; Colby T V; Wiest I; Timpl R
Increased expression of type VI collagen in lung fibrosis.
American journal of respiratory and critical care medicine 1995;151(6):1956-64.
1995: Talts J F; Weller A; Timpl R; Ekblom M; Ekblom P
Regulation of mesenchymal extracellular matrix protein synthesis by transforming growth factor-beta and glucocorticoids in tumor stroma.
Journal of cell science 1995;108 ( Pt 6)():2153-62.
1995: Mayer U; Pöschl E; Gerecke D R; Wagman D W; Burgeson R E; Timpl R
Low nidogen affinity of laminin-5 can be attributed to two serine residues in EGF-like motif gamma 2III4.
FEBS letters 1995;365(2-3):129-32.
1995: Dziadek M; Darling P; Zhang R Z; Pan T C; Tillet E; Timpl R; Chu M L
Expression of collagen alpha 1(VI), alpha 2(VI), and alpha 3(VI) chains in the pregnant mouse uterus.
Biology of reproduction 1995;52(4):885-94.
1995: Fässler R; Pfaff M; Murphy J; Noegel A A; Johansson S; Timpl R; Albrecht R
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts.
The Journal of cell biology 1995;128(5):979-88.
1995: Tillet E; Mann K; Nischt R; Pan T C; Chu M L; Timpl R
Recombinant analysis of human alpha 1 (XVI) collagen. Evidence for processing of the N-terminal globular domain.
European journal of biochemistry / FEBS 1995;228(1):160-8.
1995: Mayer U; Zimmermann K; Mann K; Reinhardt D; Timpl R; Nischt R
Binding properties and protease stability of recombinant human nidogen.
European journal of biochemistry / FEBS 1995;227(3):681-6.
1995: Sasaki T; Kostka G; Göhring W; Wiedemann H; Mann K; Chu M L; Timpl R
Structural characterization of two variants of fibulin-1 that differ in nidogen affinity.
Journal of molecular biology 1995;245(3):241-50.
1994: Pfaff M; McLane M A; Beviglia L; Niewiarowski S; Timpl R
Comparison of disintegrins with limited variation in the RGD loop in their binding to purified integrins alpha IIb beta 3, alpha V beta 3 and alpha 5 beta 1 and in cell adhesion inhibition.
Cell adhesion and communication 1994;2(6):491-501.
1994: Pfaff M; Göhring W; Brown J C; Timpl R
Binding of purified collagen receptors (alpha 1 beta 1, alpha 2 beta 1) and RGD-dependent integrins to laminins and laminin fragments.
European journal of biochemistry / FEBS 1994;225(3):975-84.
1994: Mayer U; Pöschl E; Nischt R; Specks U; Pan T C; Chu M L; Timpl R
Recombinant expression and properties of the Kunitz-type protease-inhibitor module from human type VI collagen alpha 3(VI) chain.
European journal of biochemistry / FEBS 1994;225(2):573-80.
1994: Pfaff M; Tangemann K; Müller B; Gurrath M; Müller G; Kessler H; Timpl R; Engel J
Selective recognition of cyclic RGD peptides of NMR defined conformation by alpha IIb beta 3, alpha V beta 3, and alpha 5 beta 1 integrins.
The Journal of biological chemistry 1994;269(32):20233-8.
1994: Brown J C; Golbik R; Mann K; Timpl R
Structure and stability of the triple-helical domains of human collagen XIV.
Matrix biology : journal of the International Society for Matrix Biology 1994;14(4):287-95.
1994: Timpl R; Brown J C
The laminins.
Matrix biology : journal of the International Society for Matrix Biology 1994;14(4):275-81.
1994: Ekblom P; Ekblom M; Fecker L; Klein G; Zhang H Y; Kadoya Y; Chu M L; Mayer U; Timpl R
Role of mesenchymal nidogen for epithelial morphogenesis in vitro.
Development (Cambridge, England) 1994;120(7):2003-14.
1994: Zhang R Z; Pan T C; Zhang Z Y; Mattei M G; Timpl R; Chu M L
Fibulin-2 (FBLN2): human cDNA sequence, mRNA expression, and mapping of the gene on human and mouse chromosomes.
Genomics 1994;22(2):425-30.
1994: Nerlich A G; Schleicher E D; Wiest I; Specks U; Timpl R
Immunohistochemical localization of collagen VI in diabetic glomeruli.
Kidney international 1994;45(6):1648-56.
1994: Pottgiesser J; Maurer P; Mayer U; Nischt R; Mann K; Timpl R; Krieg T; Engel J
Changes in calcium and collagen IV binding caused by mutations in the EF hand and other domains of extracellular matrix protein BM-40 (SPARC, osteonectin).
Journal of molecular biology 1994;238(4):563-74.
1994: Tillet E; Wiedemann H; Golbik R; Pan T C; Zhang R Z; Mann K; Chu M L; Timpl R
Recombinant expression and structural and binding properties of alpha 1(VI) and alpha 2(VI) chains of human collagen type VI.
European journal of biochemistry / FEBS 1994;221(1):177-85.
1994: Brown J C; Wiedemann H; Timpl R
Protein binding and cell adhesion properties of two laminin isoforms (AmB1eB2e, AmB1sB2e) from human placenta.
Journal of cell science 1994;107 ( Pt 1)():329-38.
1994: Timpl R
Proteoglycans of basement membranes.
EXS 1994;70():123-44.
1993: Pan T C; Sasaki T; Zhang R Z; Fässler R; Timpl R; Chu M L
Structure and expression of fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium binding.
The Journal of cell biology 1993;123(5):1269-77.
1993: Mayer U; Mann K; Timpl R; Murphy G
Sites of nidogen cleavage by proteases involved in tissue homeostasis and remodelling.
European journal of biochemistry / FEBS 1993;217(3):877-84.
1993: Pan T C; Kluge M; Zhang R Z; Mayer U; Timpl R; Chu M L
Sequence of extracellular mouse protein BM-90/fibulin and its calcium-dependent binding to other basement-membrane ligands.
European journal of biochemistry / FEBS 1993;215(3):733-40.
1993: Battaglia C; Aumailley M; Mann K; Mayer U; Timpl R
Structural basis of beta 1 integrin-mediated cell adhesion to a large heparan sulfate proteoglycan from basement membranes.
European journal of cell biology 1993;61(1):92-9.
1993: Timpl R
Proteoglycans of basement membranes.
Experientia 1993;49(5):417-28.
1993: Reinhardt D; Mann K; Nischt R; Fox J W; Chu M L; Krieg T; Timpl R
Mapping of nidogen binding sites for collagen type IV, heparan sulfate proteoglycan, and zinc.
The Journal of biological chemistry 1993;268(15):10881-7.
1993: Mayer U; Nischt R; Pöschl E; Mann K; Fukuda K; Gerl M; Yamada Y; Timpl R
A single EGF-like motif of laminin is responsible for high affinity nidogen binding.
The EMBO journal 1993;12(5):1879-85.
1993: Zhang R Z; Pan T C; Timpl R; Chu M L
Cloning and sequence analysis of cDNAs encoding the alpha 1, alpha 2 and alpha 3 chains of mouse collagen VI.
The Biochemical journal 1993;291 ( Pt 3)():787-92.
1993: Zhang H Y; Kluge M; Timpl R; Chu M L; Ekblom P
The extracellular matrix glycoproteins BM-90 and tenascin are expressed in the mesenchyme at sites of endothelial-mesenchymal conversion in the embryonic mouse heart.
Differentiation; research in biological diversity 1993;52(3):211-20.
1993: Aumailley M; Battaglia C; Mayer U; Reinhardt D; Nischt R; Timpl R; Fox J W
Nidogen mediates the formation of ternary complexes of basement membrane components.
Kidney international 1993;43(1):7-12.
1993: Brown J C; Mann K; Wiedemann H; Timpl R
Structure and binding properties of collagen type XIV isolated from human placenta.
The Journal of cell biology 1993;120(2):557-67.
1992: Gurrath M; Müller G; Kessler H; Aumailley M; Timpl R
Conformation/activity studies of rationally designed potent anti-adhesive RGD peptides.
European journal of biochemistry / FEBS 1992;210(3):911-21.
1992: Mann K; Gaill F; Timpl R
Amino-acid sequence and cell-adhesion activity of a fibril-forming collagen from the tube worm Riftia pachyptila living at deep sea hydrothermal vents.
European journal of biochemistry / FEBS 1992;210(3):839-47.
1992: Specks U; Mayer U; Nischt R; Spissinger T; Mann K; Timpl R; Engel J; Chu M L
Structure of recombinant N-terminal globule of type VI collagen alpha 3 chain and its binding to heparin and hyaluronan.
The EMBO journal 1992;11(12):4281-90.
1992: Battaglia C; Mayer U; Aumailley M; Timpl R
Basement-membrane heparan sulfate proteoglycan binds to laminin by its heparan sulfate chains and to nidogen by sites in the protein core.
European journal of biochemistry / FEBS 1992;208(2):359-66.
1992: Maurer P; Mayer U; Bruch M; Jenö P; Mann K; Landwehr R; Engel J; Timpl R
High-affinity and low-affinity calcium binding and stability of the multidomain extracellular 40-kDa basement membrane glycoprotein (BM-40/SPARC/osteonectin).
European journal of biochemistry / FEBS 1992;205(1):233-40.
1992: Saitta B; Timpl R; Chu M L
Human alpha 2(VI) collagen gene. Heterogeneity at the 5'-untranslated region generated by an alternate exon.
The Journal of biological chemistry 1992;267(9):6188-96.
1991: Gerl M; Mann K; Aumailley M; Timpl R
Localization of a major nidogen-binding site to domain III of laminin B2 chain.
European journal of biochemistry / FEBS 1991;202(1):167-74.
1991: Fox J W; Mayer U; Nischt R; Aumailley M; Reinhardt D; Wiedemann H; Mann K; Timpl R; Krieg T; Engel J
Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV.
The EMBO journal 1991;10(11):3137-46.
1991: Aumailley M; Gurrath M; Müller G; Calvete J; Timpl R; Kessler H
Arg-Gly-Asp constrained within cyclic pentapeptides. Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1.
FEBS letters 1991;291(1):50-4.
1991: Saitta B; Wang Y M; Renkart L; Zhang R Z; Pan T C; Timpl R; Chu M L
The exon organization of the triple-helical coding regions of the human alpha 1(VI) and alpha 2(VI) collagen genes is highly similar.
Genomics 1991;11(1):145-53.
1991: Nischt R; Pottgiesser J; Krieg T; Mayer U; Aumailley M; Timpl R
Recombinant expression and properties of the human calcium-binding extracellular matrix protein BM-40.
European journal of biochemistry / FEBS 1991;200(2):529-36.
1991: Mayer U; Aumailley M; Mann K; Timpl R; Engel J
Calcium-dependent binding of basement membrane protein BM-40 (osteonectin, SPARC) to basement membrane collagen type IV.
European journal of biochemistry / FEBS 1991;198(1):141-50.
1991: Stokes D G; Saitta B; Timpl R; Chu M L
Human alpha 3(VI) collagen gene. Characterization of exons coding for the amino-terminal globular domain and alternative splicing in normal and tumor cells.
The Journal of biological chemistry 1991;266(13):8626-33.
1990: Kluge M; Mann K; Dziadek M; Timpl R
Characterization of a novel calcium-binding 90-kDa glycoprotein (BM-90) shared by basement membranes and serum.
European journal of biochemistry / FEBS 1990;193(3):651-9.
1990: Klein G; Ekblom M; Fecker L; Timpl R; Ekblom P
Differential expression of laminin A and B chains during development of embryonic mouse organs.
Development (Cambridge, England) 1990;110(3):823-37.
1990: Sorokin L; Sonnenberg A; Aumailley M; Timpl R; Ekblom P
Recognition of the laminin E8 cell-binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubules.
The Journal of cell biology 1990;111(3):1265-73.
1990: Deutzmann R; Aumailley M; Wiedemann H; Pysny W; Timpl R; Edgar D
Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintenance of secondary and tertiary structure in its rod and globular domain.
European journal of biochemistry / FEBS 1990;191(2):513-22.
1990: Aumailley M; Timpl R; Sonnenberg A
Antibody to integrin alpha 6 subunit specifically inhibits cell-binding to laminin fragment 8.
Experimental cell research 1990;188(1):55-60.
1990: Forsberg E; Paulsson M; Timpl R; Johansson S
Characterization of a laminin receptor on rat hepatocytes.
The Journal of biological chemistry 1990;265(11):6376-81.
1990: Saitta B; Stokes D G; Vissing H; Timpl R; Chu M L
Alternative splicing of the human alpha 2(VI) collagen gene generates multiple mRNA transcripts which predict three protein variants with distinct carboxyl termini.
The Journal of biological chemistry 1990;265(11):6473-80.
1990: Aumailley M; Gerl M; Sonnenberg A; Deutzmann R; Timpl R
Identification of the Arg-Gly-Asp sequence in laminin A chain as a latent cell-binding site being exposed in fragment P1.
FEBS letters 1990;262(1):82-6.
1990: Ekblom M; Klein G; Mugrauer G; Fecker L; Deutzmann R; Timpl R; Ekblom P
Transient and locally restricted expression of laminin A chain mRNA by developing epithelial cells during kidney organogenesis.
Cell 1990;60(2):337-46.
1990: Chu M L; Pan T C; Conway D; Saitta B; Stokes D; Kuo H J; Glanville R W; Timpl R; Mann K; Deutzmann R
The structure of type VI collagen.
Annals of the New York Academy of Sciences 1990;580():55-63.
1990: Timpl R; Aumailley M; Gerl M; Mann K; Nurcombe V; Edgar D; Deutzmann R
Structure and function of the laminin-nidogen complex.
Annals of the New York Academy of Sciences 1990;580():311-23.
1989: Aumailley M; Wiedemann H; Mann K; Timpl R
Binding of nidogen and the laminin-nidogen complex to basement membrane collagen type IV.
European journal of biochemistry / FEBS 1989;184(1):241-8.
1989: Chu M L; Pan T C; Conway D; Kuo H J; Glanville R W; Timpl R; Mann K; Deutzmann R
Sequence analysis of alpha 1(VI) and alpha 2(VI) chains of human type VI collagen reveals internal triplication of globular domains similar to the A domains of von Willebrand factor and two alpha 2(VI) chain variants that differ in the carboxy terminus.
The EMBO journal 1989;8(7):1939-46.
1989: Aumailley M; Mann K; von der Mark H; Timpl R
Cell attachment properties of collagen type VI and Arg-Gly-Asp dependent binding to its alpha 2(VI) and alpha 3(VI) chains.
Experimental cell research 1989;181(2):463-74.
1989: Timpl R
Structure and biological activity of basement membrane proteins.
European journal of biochemistry / FEBS 1989;180(3):487-502.
1989: Nurcombe V; Aumailley M; Timpl R; Edgar D
The high-affinity binding of laminin to cells. Assignation of a major cell-binding site to the long arm of laminin and of a latent cell-binding site to its short arms.
European journal of biochemistry / FEBS 1989;180(1):9-14.
1989: Mann K; Deutzmann R; Aumailley M; Timpl R; Raimondi L; Yamada Y; Pan T C; Conway D; Chu M L
Amino acid sequence of mouse nidogen, a multidomain basement membrane protein with binding activity for laminin, collagen IV and cells.
The EMBO journal 1989;8(1):65-72.
1988: Chu M L; Conway D; Pan T C; Baldwin C; Mann K; Deutzmann R; Timpl R
Amino acid sequence of the triple-helical domain of human collagen type VI.
The Journal of biological chemistry 1988;263(35):18601-6.
1988: Mann K; Deutzmann R; Timpl R
Characterization of proteolytic fragments of the laminin-nidogen complex and their activity in ligand-binding assays.
European journal of biochemistry / FEBS 1988;178(1):71-80.
1988: Klein G; Langegger M; Timpl R; Ekblom P
Role of laminin A chain in the development of epithelial cell polarity.
Cell 1988;55(2):331-41.
1988: Schittny J C; Timpl R; Engel J
High resolution immunoelectron microscopic localization of functional domains of laminin, nidogen, and heparan sulfate proteoglycan in epithelial basement membrane of mouse cornea reveals different topological orientations.
The Journal of cell biology 1988;107(4):1599-610.
1988: Weber S; Dölz R; Timpl R; Fessler J H; Engel J
Reductive cleavage and reformation of the interchain and intrachain disulfide bonds in the globular hexameric domain NC1 involved in network assembly of basement membrane collagen (type IV).
European journal of biochemistry / FEBS 1988;175(2):229-36.
1987: Chu M L; Mann K; Deutzmann R; Pribula-Conway D; Hsu-Chen C C; Bernard M P; Timpl R
Characterization of three constituent chains of collagen type VI by peptide sequences and cDNA clones.
European journal of biochemistry / FEBS 1987;168(2):309-17.
1987: Paulsson M; Yurchenco P D; Ruben G C; Engel J; Timpl R
Structure of low density heparan sulfate proteoglycan isolated from a mouse tumor basement membrane.
Journal of molecular biology 1987;197(2):297-313.
1987: Aumailley M; Nurcombe V; Edgar D; Paulsson M; Timpl R
The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sites.
The Journal of biological chemistry 1987;262(24):11532-8.
1985: Aumailley M; von der Mark H; Timpl R
Size and domain structure of collagen VI produced by cultured fibroblasts.
FEBS letters 1985;182(2):499-502.
1985: Engel J; Furthmayr H; Odermatt E; von der Mark H; Aumailley M; Fleischmajer R; Timpl R
Structure and macromolecular organization of type VI collagen.
Annals of the New York Academy of Sciences 1985;460():25-37.
1984: von der Mark H; Aumailley M; Wick G; Fleischmajer R; Timpl R
Immunochemistry, genuine size and tissue localization of collagen VI.
European journal of biochemistry / FEBS 1984;142(3):493-502.
1984: Fujiwara S; Wiedemann H; Timpl R; Lustig A; Engel J
Structure and interactions of heparan sulfate proteoglycans from a mouse tumor basement membrane.
European journal of biochemistry / FEBS 1984;143(1):145-57.
1983: Furthmayr H; Wiedemann H; Timpl R; Odermatt E; Engel J
Electron-microscopical approach to a structural model of intima collagen.
The Biochemical journal 1983;211(2):303-11.
1982: Ott U; Odermatt E; Engel J; Furthmayr H; Timpl R
Protease resistance and conformation of laminin.
European journal of biochemistry / FEBS 1982;123(1):63-72.
1981: Timpl R; Wiedemann H; van Delden V; Furthmayr H; Kühn K
A network model for the organization of type IV collagen molecules in basement membranes.
European journal of biochemistry / FEBS 1981;120(2):203-11.
1981: Engel J; Odermatt E; Engel A; Madri J A; Furthmayr H; Rohde H; Timpl R
Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix.
Journal of molecular biology 1981;150(1):97-120.

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