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Jenny P-Y Ting
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19
Taxman, Debra
14
Bergstralh, Daniel
12
Lich, John
12
Linhoff, Michael
10
Harton, Jonathan
10
Moore, Chris
8
Duncan, Joseph
7
Chin, KC
7
Brickey, June
7
Arnett, Heather
7
Piskurich, Janet
7
van Deventer, Hendrik
7
Wright, Kenneth
7
Williams, Kristi
6
Zhu, Xin-Sheng
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All Publications
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2009: Willingham Stephen B; Allen Irving C; Bergstralh Daniel T; Brickey Willie June; Huang Max Tze-Han; Taxman Debra J; Duncan Joseph A; Ting Jenny P-Y
NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):2008-15.
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2009: Duncan Joseph A; Gao Xi; Huang Max Tze-Han; O'Connor Brian P; Thomas Christopher E; Willingham Stephen B; Bergstralh Daniel T; Jarvis Gary A; Sparling P Frederick; Ting Jenny P-Y
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6460-9.
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2009: Allen Irving C; Scull Margaret A; Moore Chris B; Holl Eda K; McElvania-TeKippe Erin; Taxman Debra J; Guthrie Elizabeth H; Pickles Raymond J; Ting Jenny P-Y
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.
Immunity 2009;30(4):556-65.
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2009: Huang Max Tze-Han; Taxman Debra J; Holley-Guthrie Elizabeth A; Moore Chris B; Willingham Stephen B; Madden Victoria; Parsons Rebecca Keyser; Featherstone Gerald L; Arnold Roland R; O'Connor Brian P; Ting Jenny Pan-Yun
Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2395-404.
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2009: Craven Robin R; Gao Xi; Allen Irving C; Gris Denis; Bubeck Wardenburg Juliane; McElvania-Tekippe Erin; Ting Jenny P; Duncan Joseph A
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells.
PloS one 2009;4(10):e7446.
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2009: Lei Yu; Moore Chris B; Liesman Rachael M; O'Connor Brian P; Bergstralh Daniel T; Chen Zhijian J; Pickles Raymond J; Ting Jenny P-Y
MAVS-mediated apoptosis and its inhibition by viral proteins.
PloS one 2009;4(5):e5466.
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2008: Attia Ramy R; Gardner Lidia A; Mahrous Engy; Taxman Debra J; Legros Leighton; Rowe Sarah; Ting Jenny P-Y; Geller Arthur; Kotb Malak
Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis.
The Journal of biological chemistry 2008;283(45):30788-95.
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2008: Hiremath Meenaxi M; Chen Vivian S; Suzuki Kinuko; Ting Jenny P Y; Matsushima Glenn K
MHC class II exacerbates demyelination in vivo independently of T cells.
Journal of neuroimmunology 2008;203(1):23-32.
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2008: O'Connor Brian P; Eun So-Young; Ye Zhengmao; Zozulya Alla L; Lich John D; Moore Chris B; Iocca Heather A; Roney Kelly E; Holl Eda K; Wu Quing Ping; van Deventer Hendrick W; Fabry Zsuzsanna; Ting Jenny P-Y
Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13015-20.
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2008: Willingham Stephen B; Ting Jenny P-Y
NLRs and the dangers of pollution and aging.
Nature immunology 2008;9(8):831-3.
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2008: Li Hanfen; Willingham Stephen B; Ting Jenny P-Y; Re Fabio
Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):17-21.
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2008: van Deventer Hendrik W; Wu Qing Ping; Bergstralh Daniel T; Davis Beckley K; O'Connor Brian P; Ting Jenny P-Y; Serody Jonathan S
C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9.
The American journal of pathology 2008;173(1):253-64.
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2008: Moore Chris B; Ting Jenny P-Y
Regulation of mitochondrial antiviral signaling pathways.
Immunity 2008;28(6):735-9.
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2008: Dan Han C; Cooper Matthew J; Cogswell Patricia C; Duncan Joseph A; Ting Jenny P-Y; Baldwin Albert S
Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.
Genes & development 2008;22(11):1490-500.
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2008: Ting Jenny P-Y; Willingham Stephen B; Bergstralh Daniel T
NLRs at the intersection of cell death and immunity.
Nature reviews. Immunology 2008;8(5):372-9.
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2008: Bhat Kavita P; Turner Jonathan D; Myers Sarah E; Cape Austin D; Ting Jenny P-Y; Greer Susanna F
The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription.
Molecular immunology 2008;45(8):2214-24.
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2008: Alexis Neil E; Brickey Willie June; Lay John C; Wang Ying; Roubey Robert A S; Ting Jenny P Y; Peden David B
Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2008;100(3):206-15.
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2008: Ting Jenny P-Y; Lovering Ruth C; Alnemri Emad S; Bertin John; Boss Jeremy M; Davis Beckley K; Flavell Richard A; Girardin Stephen E; Godzik Adam; Harton Jonathan A; Hoffman Hal M; Hugot Jean-Pierre; Inohara Naohiro; Mackenzie Alex; Maltais Lois J; Nunez Gabriel; Ogura Yasunori; Otten Luc A; Philpott Dana; Reed John C; Reith Walter; Schreiber Stefan; Steimle Viktor; Ward Peter A
The NLR gene family: a standard nomenclature.
Immunity 2008;28(3):285-7.
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2008: Ye Zhengmao; Lich John D; Moore Chris B; Duncan Joseph A; Williams Kristi L; Ting Jenny P-Y
ATP binding by monarch-1/NLRP12 is critical for its inhibitory function.
Molecular and cellular biology 2008;28(5):1841-50.
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2008: Iocca Heather A; Plant Sheila R; Wang Ying; Runkel Laura; O'Connor Brian P; Lundsmith Emma T; Hahm Kyungmin; van Deventer Hendrik W; Burkly Linda C; Ting Jenny P-Y
TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model.
Journal of neuroimmunology 2008;194(1-2):97-106.
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2008: Moore Chris B; Bergstralh Daniel T; Duncan Joseph A; Lei Yu; Morrison Thomas E; Zimmermann Albert G; Accavitti-Loper Mary A; Madden Victoria J; Sun Lijun; Ye Zhengmao; Lich John D; Heise Mark T; Chen Zhijian; Ting Jenny P-Y
NLRX1 is a regulator of mitochondrial antiviral immunity.
Nature 2008;451(7178):573-7.
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2008: O'Connor Brian P; Ting Jenny P-Y
The evolving role of semaphorins and plexins in the immune system: Plexin-A1 regulation of dendritic cell function.
Immunologic research 2008;41(3):217-22.
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2007: Arthur Janelle C; Lich John D; Aziz Ramy K; Kotb Malak; Ting Jenny P-Y
Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6291-6.
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2007: Moore Chris B; Medina Miguel A; van Deventer Hendrik W; O'Connor Brian P; Cameron Scott; Taxman Debra J; Maile Robert; Ting Jenny P-Y; Cairns Bruce A
Downregulation of immune signaling genes in patients with large surface burn injury.
Journal of burn care & research : official publication of the American Burn Association 2007;28(6):879-87.
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2007: Willingham Stephen B; Bergstralh Daniel T; O'Connor William; Morrison Amy C; Taxman Debra J; Duncan Joseph A; Barnoy Shoshana; Venkatesan Malabi M; Flavell Richard A; Deshmukh Mohanish; Hoffman Hal M; Ting Jenny P-Y
Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.
Cell host & microbe 2007;2(3):147-59.
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2007: Plant Sheila R; Iocca Heather A; Wang Ying; Thrash J Cameron; O'Connor Brian P; Arnett Heather A; Fu Yang-Xin; Carson Monica J; Ting Jenny P-Y
Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(28):7429-37.
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2007: Lich John D; Ting Jenny P-Y
CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses.
Proceedings of the American Thoracic Society 2007;4(3):263-6.
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2007: Duncan Joseph A; Bergstralh Daniel T; Wang Yanhong; Willingham Stephen B; Ye Zhengmao; Zimmermann Albert G; Ting Jenny Pan-Yun
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):8041-6.
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2007: Lich John D; Ting Jenny Pan-Yun
Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions.
Microbes and infection / Institut Pasteur 2007;9(5):672-6.
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2007: Duncan Joseph A; Ting Jenny Pan-Yun
Rebuilding host-pathogen interaction from the ground up: in vitro reconstitution of the inflammasome.
Cell host & microbe 2007;1(1):7-9.
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2007: Lich John D; Williams Kristi L; Moore Chris B; Arthur Janelle C; Davis Beckley K; Taxman Debra J; Ting Jenny P-Y
Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1256-60.
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2007: Shabman Reed S; Morrison Thomas E; Moore Christopher; White Laura; Suthar Mehul S; Hueston Linda; Rulli Nestor; Lidbury Brett; Ting Jenny P-Y; Mahalingam Suresh; Heise Mark T
Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses.
Journal of virology 2007;81(1):237-47.
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2007: Bergstralh Daniel T; Conti Brian J; Moore Chris B; Brickey W June; Taxman Debra J; Ting Jenny P-Y
Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription.
Experimental cell research 2007;313(1):65-76.
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2006: Kurtz Sherry; McKinnon Karen P; Runge Marschall S; Ting Jenny P-Y; Braunstein Miriam
The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response.
Infection and immunity 2006;74(12):6855-64.
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2006: Clements Casey M; McNally Richard S; Conti Brian J; Mak Tak W; Ting Jenny P-Y
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(41):15091-6.
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2006: Eun So-Young; O'Connor Brian P; Wong Athena W; van Deventer Hendrick W; Taxman Debra J; Reed William; Li Ping; Blum Janice S; McKinnon Karen P; Ting Jenny P-Y
Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4271-5.
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2006: Taxman Debra J; Zhang Jinghua; Champagne Catherine; Bergstralh Daniel T; Iocca Heather A; Lich John D; Ting Jenny Pan-Yun
Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4252-6.
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2006: Wright Kenneth L; Ting Jenny P-Y
Epigenetic regulation of MHC-II and CIITA genes.
Trends in immunology 2006;27(9):405-12.
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2006: Bergstralh Daniel T; Ting Jenny P-Y
Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination.
Cancer treatment reviews 2006;32(3):166-79.
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2006: Plant Sheila R; Wang Ying; Vasseur Sophie; Thrash J Cameron; McMahon Eileen J; Bergstralh Daniel T; Arnett Heather A; Miller Stephen D; Carson Monica J; Iovanna Juan L; Ting Jenny P-Y
Upregulation of the stress-associated gene p8 in mouse models of demyelination and in multiple sclerosis tissues.
Glia 2006;53(5):529-37.
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2006: Lich John D; Arthur Janelle C; Ting Jenny P-Y
Cryopyrin: in from the cold.
Immunity 2006;24(3):241-3.
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2006: Ting Jenny P-Y; Kastner Daniel L; Hoffman Hal M
CATERPILLERs, pyrin and hereditary immunological disorders.
Nature reviews. Immunology 2006;6(3):183-95.
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2006: Taxman Debra J; Livingstone Laura R; Zhang Jinghua; Conti Brian J; Iocca Heather A; Williams Kristi L; Lich John D; Ting Jenny P-Y; Reed William
Criteria for effective design, construction, and gene knockdown by shRNA vectors.
BMC biotechnology 2006;6():7.
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2005: Williams Kristi L; Lich John D; Duncan Joseph A; Reed William; Rallabhandi Prasad; Moore Christopher; Kurtz Sherry; Coffield V McNeil; Accavitti-Loper Mary A; Su Lishan; Vogel Stefanie N; Braunstein Miriam; Ting Jenny P-Y
The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals.
The Journal of biological chemistry 2005;280(48):39914-24.
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2005: Zika Eleni; Fauquier Lucas; Vandel Laurence; Ting Jenny P-Y
Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16321-6.
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2005: Johnnidis Jonathan B; Venanzi Emily S; Taxman Debra J; Ting Jenny P-Y; Benoist Christophe O; Mathis Diane J
Chromosomal clustering of genes controlled by the aire transcription factor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7233-8.
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2005: Conti Brian J; Davis Beckley K; Zhang Jinghua; O'connor William; Williams Kristi L; Ting Jenny P-Y
CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function.
The Journal of biological chemistry 2005;280(18):18375-85.
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2005: Ting Jenny P-Y; Williams Kristi L
The CATERPILLER family: an ancient family of immune/apoptotic proteins.
Clinical immunology (Orlando, Fla.) 2005;115(1):33-7.
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2005: van Deventer Hendrik W; O'Connor William; Brickey W June; Aris Robert M; Ting Jenny P Y; Serody Jonathan S
C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis.
Cancer research 2005;65(8):3374-9.
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2005: Zika Eleni; Ting Jenny P-Y
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
Current opinion in immunology 2005;17(1):58-64.
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2005: Plant Sheila R; Arnett Heather A; Ting Jenny P-Y
Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination.
Glia 2005;49(1):1-14.
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2005: Ting Jenny P-Y; Davis Beckley K
CATERPILLER: a novel gene family important in immunity, cell death, and diseases.
Annual review of immunology 2005;23():387-414.
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2004: Bergstralh D T; Taxman D J; Chou T C; Danishefsky S J; Ting J P Y
A comparison of signaling activities induced by Taxol and desoxyepothilone B.
Journal of chemotherapy (Florence, Italy) 2004;16(6):563-76.
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2004: Greer Susanna F; Harton Jonathan A; Linhoff Michael W; Janczak Christin A; Ting Jenny P-Y; Cressman Drew E
Serine residues 286, 288, and 293 within the CIITA: a mechanism for down-regulating CIITA activity through phosphorylation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):376-83.
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2004: Arancibia-Cárcamo Carolina V; Osawa Hideya; Arnett Heather A; Háskova Zdenka; George Andrew J T; Ono Santa J; Ting Jenny P-Y; Streilein J Wayne
A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites.
European journal of immunology 2004;34(2):471-80.
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2003: O'Connor William; Harton Jonathan A; Zhu Xinsheng; Linhoff Michael W; Ting Jenny P-Y
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6329-33.
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2003: Greer Susanna F; Zika Eleni; Conti Brian; Zhu Xin-Sheng; Ting Jenny P-Y
Enhancement of CIITA transcriptional function by ubiquitin.
Nature immunology 2003;4(11):1074-82.
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2003: Arnett Heather A; Wang Ying; Matsushima Glenn K; Suzuki Kinuko; Ting Jenny P-Y
Functional genomic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(30):9824-32.
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2003: MacKeigan Jeffrey P; Clements Casey M; Lich John D; Pope R Marshall; Hod Yaacov; Ting Jenny P-Y
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha.
Cancer research 2003;63(20):6928-34.
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2003: Wong Athena W; Brickey W June; Taxman Debra J; van Deventer Hendrick W; Reed William; Gao Jian Xin; Zheng Pan; Liu Yang; Li Ping; Blum Janice S; McKinnon Karen P; Ting Jenny P-Y
CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions.
Nature immunology 2003;4(9):891-8.
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2003: Taxman Debra J; MacKeigan Jeffrey P; Clements Casey; Bergstralh Daniel T; Ting Jenny P-Y
Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor.
Cancer research 2003;63(16):5095-104.
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2003: Williams Kristi L; Taxman Debra J; Linhoff Michael W; Reed William; Ting Jenny P-Y
Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5354-8.
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2003: Zika Eleni; Greer Susanna F; Zhu Xin-Sheng; Ting Jenny P-Y
Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation.
Molecular and cellular biology 2003;23(9):3091-102.
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2002: June Brickey W; Felix Nathan J; Griffiths Robert; Zhang Jinghua; Wang Bo; Piskurich Janet F; Itoh-Lindstrom Yoshie; Coffman Thomas M; Ting Jenny P-Y
Prolonged survival of class II transactivator-deficient cardiac allografts.
Transplantation 2002;74(9):1341-8.
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2002: Harton Jonathan A; Linhoff Michael W; Zhang Jinghua; Ting Jenny P-Y
Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(8):4088-93.
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2002: Wong Athena W; Ghosh Nilanjan; McKinnon Karen P; Reed William; Piskurich Janet F; Wright Kenneth L; Ting Jenny P-Y
Regulation and specificity of MHC2TA promoter usage in human primary T lymphocytes and cell line.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):3112-9.
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2002: van Deventer Hendrik W; Serody Jonathon S; McKinnon Karen P; Clements Casey; Brickey W June; Ting Jenny P-Y
Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1634-9.
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2002: MacKeigan Jeffrey P; Taxman Debra J; Hunter Deborah; Earp H Shelton; Graves Lee M; Ting Jenny P-Y
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2091-9.
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2002: Harton Jonathan A; O'Connor William; Conti Brian J; Linhoff Michael W; Ting Jenny P-Y
Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation.
Human immunology 2002;63(7):588-601.
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2002: Ting Jenny Pan-Yun; Trowsdale John
Genetic control of MHC class II expression.
Cell 2002;109 Suppl():S21-33.
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2002: Tompkins Stephen Mark; Padilla Josette; Dal Canto Mauro C; Ting Jenny P-Y; Van Kaer Luc; Miller Stephen D
De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4173-83.
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2002: Felix Nathan J; de Serres Suzan; Meyer Anthony A; Ting Jenny P-Y
Comparison of Abeta(b-/-), H2-DM(-), and CIITA(-/-) in second-set skin allograft rejection.
The Journal of surgical research 2002;102(2):185-92.
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2002: Arnett Heather A; Hellendall Ron P; Matsushima Glenn K; Suzuki Kinuko; Laubach Victor E; Sherman Paula; Ting Jenny P-Y
The protective role of nitric oxide in a neurotoxicant-induced demyelinating model.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):427-33.
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2001: Morrison T E; Mauser A; Wong A; Ting J P; Kenney S C
Inhibition of IFN-gamma signaling by an Epstein-Barr virus immediate-early protein.
Immunity 2001;15(5):787-99.
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2001: Arnett H A; Mason J; Marino M; Suzuki K; Matsushima G K; Ting J P
TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination.
Nature neuroscience 2001;4(11):1116-22.
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2001: Zhu X S; Ting J P
A 36-amino-acid region of CIITA is an effective inhibitor of CBP: novel mechanism of gamma interferon-mediated suppression of collagen alpha(2)(I) and other promoters.
Molecular and cellular biology 2001;21(20):7078-88.
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2001: Cressman D E; O'Connor W J; Greer S F; Zhu X S; Ting J P
Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3626-34.
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2001: Harton J A; Zika E; Ting J P
The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivator.
The Journal of biological chemistry 2001;276(42):38715-20.
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2001: Li G; Harton J A; Zhu X; Ting J P
Downregulation of CIITA function by protein kinase a (PKA)-mediated phosphorylation: mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines.
Molecular and cellular biology 2001;21(14):4626-35.
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2001: Linhoff M W; Harton J A; Cressman D E; Martin B K; Ting J P
Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains.
Molecular and cellular biology 2001;21(9):3001-11.
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2000: Piskurich J F; Lin K I; Lin Y; Wang Y; Ting J P; Calame K
BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells.
Nature immunology 2000;1(6):526-32.
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2000: MacKeigan J P; Collins T S; Ting J P
MEK inhibition enhances paclitaxel-induced tumor apoptosis.
The Journal of biological chemistry 2000;275(50):38953-6.
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2000: Harton J A; Ting J P
Class II transactivator: mastering the art of major histocompatibility complex expression.
Molecular and cellular biology 2000;20(17):6185-94.
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2000: Zhu X S; Linhoff M W; Li G; Chin K C; Maity S N; Ting J P
Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter.
Molecular and cellular biology 2000;20(16):6051-61.
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2000: Taxman D J; Cressman D E; Ting J P
Identification of class II transcriptional activator-induced genes by representational difference analysis: discoordinate regulation of the DN alpha/DO beta heterodimer.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1410-6.
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2000: Felix N J; Brickey W J; Griffiths R; Zhang J; Van Kaer L; Coffman T; Ting J P
H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection.
The Journal of experimental medicine 2000;192(1):31-40.
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2000: Collins T S; Lee L F; Ting J P
Paclitaxel up-regulates interleukin-8 synthesis in human lung carcinoma through an NF-kappaB- and AP-1-dependent mechanism.
Cancer immunology, immunotherapy : CII 2000;49(2):78-84.
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2000: Lee L F; Hellendall R P; Wang Y; Haskill J S; Mukaida N; Matsushima K; Ting J P
IL-8 reduced tumorigenicity of human ovarian cancer in vivo due to neutrophil infiltration.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(5):2769-75.
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1999: Brickey W J; Wright K L; Zhu X S; Ting J P
Analysis of the defect in IFN-gamma induction of MHC class II genes in G1B cells: identification of a novel and functionally critical leucine-rich motif (62-LYLYLQL-68) in the regulatory factor X 5 transcription factor.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6622-30.
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1999: Ghosh N; Piskurich J F; Wright G; Hassani K; Ting J P; Wright K L
A novel element and a TEF-2-like element activate the major histocompatibility complex class II transactivator in B-lymphocytes.
The Journal of biological chemistry 1999;274(45):32342-50.
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1999: Nikcevich K M; Piskurich J F; Hellendall R P; Wang Y; Ting J P
Differential selectivity of CIITA promoter activation by IFN-gamma and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-alpha.
Journal of neuroimmunology 1999;99(2):195-204.
-
1999: Ting J P; Zhu X S
Class II MHC genes: a model gene regulatory system with great biologic consequences.
Microbes and infection / Institut Pasteur 1999;1(11):855-61.
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1999: Itoh-Lindstrom Y; Piskurich J F; Felix N J; Wang Y; Brickey W J; Platt J L; Koller B H; Ting J P
Reduced IL-4-, lipopolysaccharide-, and IFN-gamma-induced MHC class II expression in mice lacking class II transactivator due to targeted deletion of the GTP-binding domain.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2425-31.
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1999: Harton J A; Cressman D E; Chin K C; Der C J; Ting J P
GTP binding by class II transactivator: role in nuclear import.
Science (New York, N.Y.) 1999;285(5432):1402-5.
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1999: Martin B K; Frelinger J G; Ting J P
Combination gene therapy with CD86 and the MHC class II transactivator in the control of lung tumor growth.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6663-70.
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1999: Cressman D E; Chin K C; Taxman D J; Ting J P
A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome.
Immunity 1999;10(2):163-71.
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1999: Piskurich J F; Linhoff M W; Wang Y; Ting J P
Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta.
Molecular and cellular biology 1999;19(1):431-40.
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1998: Hiremath M M; Saito Y; Knapp G W; Ting J P; Suzuki K; Matsushima G K
Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice.
Journal of neuroimmunology 1998;92(1-2):38-49.
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1998: Lee L F; Li G; Templeton D J; Ting J P
Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK).
The Journal of biological chemistry 1998;273(43):28253-60.
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1998: Wright K L; Chin K C; Linhoff M; Skinner C; Brown J A; Boss J M; Stark G R; Ting J P
CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6267-72.
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1998: White C M; Martin B K; Lee L F; Haskill J S; Ting J P
Effects of paclitaxel on cytokine synthesis by unprimed human monocytes, T lymphocytes, and breast cancer cells.
Cancer immunology, immunotherapy : CII 1998;46(2):104-12.
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1998: Piskurich J F; Wang Y; Linhoff M W; White L C; Ting J P
Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):233-40.
-
1997: Ting J P; Wright K L; Chin K C; Brickey W J; Li G
The DMB promoter: delineation, in vivo footprint, trans-activation, and trans-dominant suppression.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5457-62.
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1997: Chin K C; Li G; Ting J P
Activation and transdominant suppression of MHC class II and HLA-DMB promoters by a series of C-terminal class II transactivator deletion mutants.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(6):2789-94.
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1997: Lee L F; Haskill J S; Mukaida N; Matsushima K; Ting J P
Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter.
Molecular and cellular biology 1997;17(9):5097-105.
-
1997: Linhoff M W; Wright K L; Ting J P
CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein complex that spans 250 base pairs: the invariant chain promoter as a model.
Molecular and cellular biology 1997;17(8):4589-96.
-
1997: Katula K S; Wright K L; Paul H; Surman D R; Nuckolls F J; Smith J W; Ting J P; Yates J; Cogswell J P
Cyclin-dependent kinase activation and S-phase induction of the cyclin B1 gene are linked through the CCAAT elements.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(7):811-20.
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1997: Martin B K; Chin K C; Olsen J C; Skinner C A; Dey A; Ozato K; Ting J P
Induction of MHC class I expression by the MHC class II transactivator CIITA.
Immunity 1997;6(5):591-600.
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1997: Hellendall R P; Ting J P
Differential regulation of cytokine-induced major histocompatibility complex class II expression and nitric oxide release in rat microglia and astrocytes by effectors of tyrosine kinase, protein kinase C, and cAMP.
Journal of neuroimmunology 1997;74(1-2):19-29.
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1997: Chin K C; Li G G; Ting J P
Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2501-6.
-
1996: White L C; Wright K L; Felix N J; Ruffner H; Reis L F; Pine R; Ting J P
Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice.
Immunity 1996;5(4):365-76.
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1996: Lee L F; Schuerer-Maly C C; Lofquist A K; van Haaften-Day C; Ting J P; White C M; Martin B K; Haskill J S
Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer.
Cancer research 1996;56(6):1303-8.
-
1995: Wright K L; Moore T L; Vilen B J; Brown A M; Ting J P
Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y.
The Journal of biological chemistry 1995;270(36):20978-86.
-
1995: Wright K L; White L C; Kelly A; Beck S; Trowsdale J; Ting J P
Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter.
The Journal of experimental medicine 1995;181(4):1459-71.
-
1995: MacDonald G H; Itoh-Lindstrom Y; Ting J P
The transcriptional regulatory protein, YB-1, promotes single-stranded regions in the DRA promoter.
The Journal of biological chemistry 1995;270(8):3527-33.
-
1995: Itoh-Lindstrom Y; Peterlin B M; Ting J P
Affinity enrichment and functional characterization of TRAX1, a novel transcription activator and X1-sequence-binding protein of HLA-DRA.
Molecular and cellular biology 1995;15(1):282-9.
-
1994: Panek R B; Lee Y J; Itoh-Lindstrom Y; Ting J P; Benveniste E N
Characterization of astrocyte nuclear proteins involved in IFN-gamma- and TNF-alpha-mediated class II MHC gene expression.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(10):4555-64.
-
1994: Chen X; Wright K L; Berkowitz E A; Azizkhan J C; Ting J P; Lee D C
Protein interactions at Sp1-like sites in the TGF alpha promoter as visualized by in vivo genomic footprinting.
Oncogene 1994;9(11):3179-87.
-
1994: Chin K C; Mao C; Skinner C; Riley J L; Wright K L; Moreno C S; Stark G R; Boss J M; Ting J P
Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction.
Immunity 1994;1(8):687-97.
-
1994: Wright K L; Vilen B J; Itoh-Lindstrom Y; Moore T L; Li G; Criscitiello M; Cogswell P; Clarke J B; Ting J P
CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors.
The EMBO journal 1994;13(17):4042-53.
-
1994: Matsushima G K; Taniike M; Glimcher L H; Grusby M J; Frelinger J A; Suzuki K; Ting J P
Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy.
Cell 1994;78(4):645-56.
-
1994: Brown A M; Linhoff M W; Stein B; Wright K L; Baldwin A S; Basta P V; Ting J P
Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits.
Molecular and cellular biology 1994;14(5):2926-35.
-
1994: Ting J P; Painter A; Zeleznik-Le N J; MacDonald G; Moore T M; Brown A; Schwartz B D
YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.
The Journal of experimental medicine 1994;179(5):1605-11.
-
1993: Brown A M; Wright K L; Ting J P
Human major histocompatibility complex class II-associated invariant chain gene promoter. Functional analysis and in vivo protein/DNA interactions of constitutive and IFN-gamma-induced expression.
The Journal of biological chemistry 1993;268(35):26328-33.
-
1993: Matsushima G K; Itoh-Lindstrom Y; Ting J P
Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements.
Molecular and cellular biology 1993;13(8):5132.
-
1993: Cogswell J P; Cogswell P C; Kuehl W M; Cuddihy A M; Bender T M; Engelke U; Marcu K B; Ting J P
Mechanism of c-myc regulation by c-Myb in different cell lineages.
Molecular and cellular biology 1993;13(5):2858-69.
-
1993: Ting J P; Baldwin A S
Regulation of MHC gene expression.
Current opinion in immunology 1993;5(1):8-16.
-
1992: Panek R B; Moses H; Ting J P; Benveniste E N
Tumor necrosis factor alpha response elements in the HLA-DRA promoter: identification of a tumor necrosis factor alpha-induced DNA-protein complex in astrocytes.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11518-22.
-
1992: Matsushima G K; Itoh-Lindstrom Y; Ting J P
Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements.
Molecular and cellular biology 1992;12(12):5610-9.
-
1992: Vilen B J; Penta J F; Ting J P
Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-gamma-inducible expression of the HLA-DRA gene.
The Journal of biological chemistry 1992;267(33):23728-34.
-
1992: Wright K L; Ting J P
In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7601-5.
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1992: Moses H; Panek R B; Benveniste E N; Ting J P
Usage of primary cells to delineate IFN-gamma-responsive DNA elements in the HLA-DRA promoter and to identify a novel IFN-gamma-enhanced nuclear factor.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(11):3643-51.
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1992: Zeleznik-Le N J; Itoh-Lindstrom Y; Clarke J B; Moore T L; Ting J P
The B cell-specific nuclear factor OTF-2 positively regulates transcription of the human class II transplantation gene, DRA.
The Journal of biological chemistry 1992;267(11):7677-82.
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1991: Vilen B J; Cogswell J P; Ting J P
Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function.
Molecular and cellular biology 1991;11(5):2406-15.
-
1991: Brown A M; Barr C L; Ting J P
Sequences homologous to class II MHC W, X, and Y elements mediate constitutive and IFN-gamma-induced expression of human class II-associated invariant chain gene.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(9):3183-9.
-
1991: Moses H; Sasaki A; Ting J P
Identification of an interferon-gamma-responsive element of a class II major histocompatibility gene in rat type 1 astrocytes.
Journal of neuroimmunology 1991;31(3):273-8.
-
1991: Zeleznik-Le N J; Azizkhan J C; Ting J P
Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1873-7.
-
1991: Cogswell J P; Austin J; Ting J P
The W element is a positive regulator of HLA-DRA transcription in various DR+ cell types.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(4):1361-7.
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1991: Cogswell J P; Zeleznik-Le N; Ting J P
Transcriptional regulation of the HLA-DRA gene.
Critical reviews in immunology 1991;11(2):87-112.
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1990: Cogswell J P; Basta P V; Ting J P
X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7703-7.
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1990: Liou H C; Boothby M R; Finn P W; Davidon R; Nabavi N; Zeleznik-Le N J; Ting J P; Glimcher L H
A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter.
Science (New York, N.Y.) 1990;247(4950):1581-4.
-
1989: Katagiri T; Ting J P; Dy R; Prokop C; Cohen P; Earp H S
Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr mice.
Molecular and cellular biology 1989;9(11):4914-22.
-
1989: Sherman P A; Basta P V; Heguy A; Wloch M K; Roeder R G; Ting J P
The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6739-43.
-
1989: Basta P V; Moore T L; Yokota S; Ting J P
A beta-adrenergic agonist modulates DR alpha gene transcription via enhanced cAMP levels in a glioblastoma multiforme line.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(8):2895-901.
-
1989: Sherman P A; Basta P V; Moore T L; Brown A M; Ting J P
Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins.
Molecular and cellular biology 1989;9(1):50-6.
-
1988: Basta P V; Sherman P A; Ting J P
Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8618-22.
-
1988: Katagiri K; Katagiri T; Yokota S; Eisenberg R A; Cohen P L; Ting J P
Two different molecular pathways account for low IL-2 receptor and c-myc mRNA expression by lpr Lyt-2- L3T4- T cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):2145-52.
-
1987: Evans J L; Boyle W J; Ting J P
Molecular basis of elevated c-myb expression in the abnormal L3T4-, Lyt-2- T lymphocytes of autoimmune mice.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(10):3497-505.
-
1987: Yokota S; Yuan D; Katagiri T; Eisenberg R A; Cohen P L; Ting J P
The expression and regulation of c-myb transcription in B6/lpr Lyt-2-, L3T4-T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(8):2810-7.
-
1987: Sherman P A; Basta P V; Ting J P
Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(12):4254-8.
-
1987: Basta P V; Sherman P A; Ting J P
Identification of an interferon-gamma response region 5' of the human histocompatibility leukocyte antigen DR alpha chain gene which is active in human glioblastoma multiforme lines.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(4):1275-80.
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