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Inge Tinhofer

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Inge Tinhofer; Tsvetana Hristozova; Ulrich Keilhoiz; Carmen Stromberger; Volker Budach
Monitoring of circulating tumor cells and their expression of EGFR/phospho-EGFR during combined radiotherapy regimens in locally advanced squamous cell carcinoma of the head and neck.
Tsvetana Hristozova; Robert Konschak; Volker Budach; Inge Tinhofer
A simple multicolor flow cytometry protocol for detection and molecular characterization of circulating tumor cells in epithelial cancers.
Carmen Holz; Tsvetana Hristozova; Franziska Niehr; Mariya Boyko; Volker Budach; Luitpold Distel; Inge Tinhofer
Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells.

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2012: Inge Tinhofer; Tsvetana Hristozova; Ulrich Keilhoiz; Carmen Stromberger; Volker Budach
Monitoring of circulating tumor cells and their expression of EGFR/phospho-EGFR during combined radiotherapy regimens in locally advanced squamous cell carcinoma of the head and neck.
International journal of radiation oncology, biology, physics 2012;83(5):e685-90.
2012: Tsvetana Hristozova; Robert Konschak; Volker Budach; Inge Tinhofer
A simple multicolor flow cytometry protocol for detection and molecular characterization of circulating tumor cells in epithelial cancers.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012;81(6):489-95.
2011: Carmen Holz; Tsvetana Hristozova; Franziska Niehr; Mariya Boyko; Volker Budach; Luitpold Distel; Inge Tinhofer
Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011;101(1):158-64.
2011: J Piñón Hofbauer; C Holler; T Kocher; Inge Tinhofer; D Trapin; D Asslaber; U Denk; richard greil; C Heyder; Alexander Egle
Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.
Leukemia 2011;25(9):1452-8.
2011: T Hristozova; Ulrich Keilholz; R Konschak; Z Liu; A Stenzinger; Carmen Stromberger; Volker Budach; A Fusi; W Weichert; Inge Tinhofer
The presence of circulating tumor cells (CTCs) correlates with lymph node metastasis in nonresectable squamous cell carcinoma of the head and neck region (SCCHN).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2011;22(8):1878-85.
2011: Lukas Weiss; Thomas Melchardt; Alexander Egle; Christoph Grabmer; Richard Greil; Inge Tinhofer
Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia.
Cancer 2011;117(10):2163-9.
2011: Franz Josef Gassner; Lukas Weiss; Roland Geisberger; Josefina Piñón Hofbauer; Alexander Egle; Tanja Nicole Hartmann; richard greil; Inge Tinhofer
Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia.
Cancer immunology, immunotherapy : CII 2011;60(1):75-85.
2010: Michael Fiegl; Martin Erdel; Inge Tinhofer; Y Brychtova; A Panovska; M Doubek; K Eigenberger; C Fonatsch; G Hopfinger; H Mühlberger; August Zabernigg; F Falkner; Guenther Gastl; J Mayer; richard greil
Clinical outcome of pretreated B-cell chronic lymphocytic leukemia following alemtuzumab therapy: a retrospective study on various cytogenetic risk categories.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(12):2410-9.
2010: Sebastian Walter Hofbauer; Josefina D Piñón; Gabriele Brachtl; Lucia Haginger; Wei Wang; Karin Jöhrer; Inge Tinhofer; Tanja Nicole Hartmann; richard greil
Modifying akt signaling in B-cell chronic lymphocytic leukemia cells.
Cancer research 2010;70(18):7336-44.
2010: P Desch; D Asslaber; D Kern; Harald SCHNIDAR; D Mangelberger; Beate Alinger; M Stoecher; Sebastian Walter Hofbauer; Daniel Neureiter; Inge Tinhofer; Fritz Aberger; T N Hartmann; richard greil
Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Oncogene 2010;29(35):4885-95.
2010: Daniela Asslaber; Josefina D Piñón; Irina Seyfried; Petra Desch; Markus Stöcher; Inge Tinhofer; Alexander Egle; Olaf Merkel; richard greil
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.
Blood 2010;115(21):4191-7.
2010: Brigitte Sinn; Gesche Tallen; Gisela Schroeder; Birgit Grassl; Joern Schulze; Volker Budach; Inge Tinhofer
Caffeine confers radiosensitization of PTEN-deficient malignant glioma cells by enhancing ionizing radiation-induced G1 arrest and negatively regulating Akt phosphorylation.
Molecular cancer therapeutics 2010;9(2):480-8.
2009: Inge Tinhofer; Lukas Weiss; Franz Gassner; Gabriele Rubenzer; Claudia Holler; richard greil
Difference in the relative distribution of CD4+ T-cell subsets in B-CLL with mutated and unmutated immunoglobulin (Ig) VH genes: implication for the course of disease.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(3):302-9.
2008: Irina Seyfried; Sebastian Walter Hofbauer; Markus Stoecher; richard greil; Inge Tinhofer
SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a.
Blood 2008;112(5):2168; author reply 2169.
2008: Irina Gryshchenko; Sebastian Walter Hofbauer; Markus Stoecher; Peter T Daniel; Michael Steurer; Alexander Gaiger; Karin Eigenberger; richard greil; Inge Tinhofer
MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(14):2252-7.
2008: Olaf Merkel; Christoph Heyder; Daniela Asslaber; Frank Hamacher; Inge Tinhofer; Claudia Holler; Markus Stöcher; Andreas Prokesch; Christine Papak; Marcel Scheideler; Zlatko Trajanoski; richard greil
Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13.
Journal of molecular medicine (Berlin, Germany) 2008;86(5):541-52.
2007: Karl Maly; Georg Hechenberger; Kukka Strese; Inge Tinhofer; Irene Wede; Wolfgang Doppler; Hans H Grunicke
Regulation of calcium signalling by the small GTP-binding proteins Ras and Rac1.
Advances in enzyme regulation 2007;47():169-83.
2006: Inge Tinhofer; Gabriele Rubenzer; Claudia Holler; Elisabeth Hofstaetter; Markus Stoecher; Alexander Egle; Michael Steurer; richard greil
Expression levels of CD38 in T cells predict course of disease in male patients with B-chronic lymphocytic leukemia.
Blood 2006;108(9):2950-6.
2006: Inge Tinhofer; Michael Steurer; Gabriele Leitinger; Holger Rumpold; Alexander Egle; Martin Erdel; richard greil
The effect of IgVH mutational status on the induction of apoptosis by rituximab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: evidence from a clinical phase I/II trial.
Haematologica 2006;91(9):1291-3.
2006: Matthias Keller; Georg Simbruner; Agnieszka Górna; Martina Urbanek; Inge Tinhofer; Elke Griesmaier; Gergely Sárközy; Leslie Schwendimann; Pierre Gressens
Systemic application of granulocyte-colony stimulating factor and stem cell factor exacerbates excitotoxic brain injury in newborn mice.
Pediatric research 2006;59(4 Pt 1):549-53.
2006: Inge Tinhofer; Rainer Biedermann; Martin Krismer; Roman Crazzolara; richard greil
A role of TRAIL in killing osteoblasts by myeloma cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):759-61.
2005: Thomas Gruber; Johannes Barsig; Christa Pfeifhofer; Nassim Ghaffari Tabrizi; Inge Tinhofer; Michael Leitges; Gottfried Baier
PKCdelta is involved in signal attenuation in CD3+ T cells.
Immunology letters 2005;96(2):291-3.
2003: richard greil; Gabriele Anether; Karin Johrer; Inge Tinhofer
Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools.
Journal of leukocyte biology 2003;74(3):311-30.
2003: David Bernhard; Wolfgang Schwaiger; Roman Crazzolara; Inge Tinhofer; Reinhard Kofler; Adam Csordas
Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells.
Cancer letters 2003;195(2):193-9.
2003: Gabriele Anether; Inge Tinhofer; Monika Senfter; richard greil
Tetrocarcin-A--induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway.
Blood 2003;101(11):4561-8.
2003: richard greil; Gabriele Anether; Karin Johrer; Inge Tinhofer
Tuning the rheostat of the myelopoietic system via Fas and TRAIL.
Critical reviews in immunology 2003;23(4):301-22.
2002: Inge Tinhofer; Gabriele Anether; Monika Senfter; Kristian Pfaller; David Bernhard; Mitsunobu Hara; richard greil
Stressful death of T-ALL tumor cells after treatment with the anti-tumor agent Tetrocarcin-A.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1295-7.
2002: Gabriele Anether; Ingrid Marschitz; Inge Tinhofer; richard greil
Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia.
Blood 2002;99(2):722-3.
2001: David Bernhard; S Skvortsov; Inge Tinhofer; H Hübl; richard greil; Adam Csordas; Reinhard Kofler
Inhibition of histone deacetylase activity enhances Fas receptor-mediated apoptosis in leukemic lymphoblasts.
Cell death and differentiation 2001;8(10):1014-21.
2001: Inge Tinhofer; David Bernhard; Monika Senfter; Gabriele Anether; Markus Loeffler; G Kroemer; Reinhard Kofler; Adam Csordas; richard greil
Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1613-5.
2000: David Bernhard; Inge Tinhofer; Martin Tonko; H Hübl; Michael J Ausserlechner; richard greil; Reinhard Kofler; Adam Csordas
Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells.
Cell death and differentiation 2000;7(9):834-42.
2000: Inge Tinhofer; H Wykypiel; Ingrid Marschitz; T Henn; richard greil
Gastric cancer cell lines lack Fas ligand (FasL) expression but kill T cells via a FasL independent pathway.
Gut 2000;46(5):738-40.
2000: Ingrid Marschitz; Inge Tinhofer; Anton Hittmair; Alexander Egle; M Kos; richard greil
Analysis of Bcl-2 protein expression in chronic lymphocytic leukemia. A comparison of three semiquantitation techniques.
American journal of clinical pathology 2000;113(2):219-29.
2000: Inge Tinhofer; Ingrid Marschitz; T Henn; Alexander Egle; richard greil
Expression of functional interleukin-15 receptor and autocrine production of interleukin-15 as mechanisms of tumor propagation in multiple myeloma.
Blood 2000;95(2):610-8.
1999: Andreas Villunger; Nassim Ghaffari Tabrizi; Inge Tinhofer; Nina Krumböck; Birgit Bauer; T Schneider; S Kasibhatla; richard greil; Gabriele Baier-Bitterlich; Florian Uberall; D R Green; Gottfried Baier
Synergistic action of protein kinase C theta and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells.
European journal of immunology 1999;29(11):3549-61.
1998: Andreas Villunger; Alexander Egle; M Kos; D Egle; Inge Tinhofer; T Henn; Florian Uberall; Karl Maly; richard greil
Functional granulocyte/macrophage colony stimulating factor receptor is constitutively expressed on neoplastic plasma cells and mediates tumour cell longevity.
British journal of haematology 1998;102(4):1069-80.
1998: Inge Tinhofer; Ingrid Marschitz; M Kos; T Henn; Alexander Egle; Andreas Villunger; richard greil
Differential sensitivity of CD4+ and CD8+ T lymphocytes to the killing efficacy of Fas (Apo-1/CD95) ligand+ tumor cells in B chronic lymphocytic leukemia.
Blood 1998;91(11):4273-81.
1997: Esther Zwick; Henrik Daub; N Aoki; Y Yamaguchi-Aoki; Inge Tinhofer; Karl Maly; Axel Ullrich
Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling.
The Journal of biological chemistry 1997;272(40):24767-70.
1996: Inge Tinhofer; Karl Maly; Paul Dietl; F Hochholdinger; S Mayr; A Obermeier; Hans H Grunicke
Differential Ca2+ signaling induced by activation of the epidermal growth factor and nerve growth factor receptors.
The Journal of biological chemistry 1996;271(48):30505-9.
1996: A Obermeier; Inge Tinhofer; Hans H Grunicke; A Ullrich
Transforming potentials of epidermal growth factor and nerve growth factor receptors inversely correlate with their phospholipase C gamma affinity and signal activation.
The EMBO journal 1996;15(1):73-82.
1995: Karl Maly; E Kindler; Inge Tinhofer; Hans H Grunicke
Activation of Ca2+ influx by transforming Ha-ras.
Cell calcium 1995;18(2):120-34.