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Yin Tintut

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Rongsong Li; David Mittelstein; Mohamad Navab; Payam Pakbin; Constantinos Sioutas; Yin Tintut; Yunfeng Du; Winnie Kam; Tzung K Hsiai
Atmospheric ultrafine particles promote vascular calcification via the NF-κB signaling pathway.
Jinxiu Lu; Diana M Shih; E Atti; Henry Cheng; Linda L Demer; Yin Tintut
Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice.
Margaret N Wong; Xingjuan Zeng; Xin Zhao; Ting-Hsuan Chen; Eric M Demer; Jeffrey J Hsu; Timothy P Nguyen; Aman Saw; Yin Tintut; Linda L Demer
Preferred mitotic orientation in pattern formation by vascular mesenchymal cells.

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All Publications

2013: Rongsong Li; David Mittelstein; Mohamad Navab; Payam Pakbin; Constantinos Sioutas; Yin Tintut; Yunfeng Du; Winnie Kam; Tzung K Hsiai
Atmospheric ultrafine particles promote vascular calcification via the NF-κB signaling pathway.
American journal of physiology. Cell physiology 2013;304(4):C362-9.
2013: Jinxiu Lu; Diana M Shih; E Atti; Henry Cheng; Linda L Demer; Yin Tintut
Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice.
Biochemical and biophysical research communications 2013;431(1):19-24.
2012: Margaret N Wong; Xingjuan Zeng; Xin Zhao; Ting-Hsuan Chen; Eric M Demer; Jeffrey J Hsu; Timothy P Nguyen; Aman Saw; Yin Tintut; Linda L Demer
Preferred mitotic orientation in pattern formation by vascular mesenchymal cells.
American journal of physiology. Heart and circulatory physiology 2012;303(12):H1411-7.
2012: Sean Morony; A P Sage; Yin Tintut; T Corbin; J Lu; L L Demer
Enhanced mineralization potential of vascular cells from SM22α-Rankl (tg) mice.
Calcified tissue international 2012;91(6):379-86.
2012: Ting-Hsuan Chen; Linda L Demer; Alan Garfinkel; Leiting Pan; Yin Tintut; Xingjuan Zeng; Xin Zhao; Xiaolu Zhu; Chih-Ming Ho
Directing tissue morphogenesis via self-assembly of vascular mesenchymal cells.
Biomaterials 2012;33(35):9019-26.
2012: Ting-Hsuan Chen; Linda L Demer; Kristina I Boström; Chunyan Guo; Chih-Ming Ho; Yin Tintut; Margaret N Wong; Yucheng Yao; Xin Zhao; Alan Garfinkel
Patterns of periodic holes created by increased cell motility.
Interface focus 2012;2(4):457-64.
2012: Ting-Hsuan Chen; Alan Garfinkel; Chunyan Guo; Chih-Ming Ho; Jeffrey J Hsu; Yi Huang; Zongwei Li; Yin Tintut; Margaret N Wong; Xin Zhao; Linda L Demer
Left-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics.
Circulation research 2012;110(4):551-9.
2012: Rongsong Li; Rohit Majumdar; David Mittelstein; Yin Tintut; Linda L Demer; Karen Fang; Juhyun Lee; Tzung K Hsiai
A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases.
American journal of physiology. Cell physiology 2012;302(4):C658-65.
2012: Flavia Pirih; Sotirios Tetradis; Fei Ye; Tara L Aghaloo; Maria-Grazia Ascenzi; E Atti; Olga Bezouglaia; Linda L Demer; Jinxiu Lu; Yin Tintut
Adverse effects of hyperlipidemia on bone regeneration and strength.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(2):309-18.
2012: Henry Cheng; Alan Garfinkel; Jinxiu Lu; Aneela Reddy; Andrew Sage; Yin Tintut; Linda L Demer
Focal high cell density generates a gradient of patterns in self-organizing vascular mesenchymal cells.
Journal of vascular research 2012;49(5):441-6.
2011: Yifan Geng; Jeffrey J Hsu; Jinxiu Lu; Makoto Miyazaki; Tabitha C Ting; Linda L Demer; Yin Tintut
Role of cellular cholesterol metabolism in vascular cell calcification.
The Journal of biological chemistry 2011;286(38):33701-6.
2011: Tabitha C Ting; Yin Tintut; Shinobu Miyazaki-Anzai; Linda L Demer; Moshe Levi; Masashi Masuda; Makoto Miyazaki
Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells.
The Journal of biological chemistry 2011;286(27):23938-49.
2011: Linda L Demer; Yin Tintut
The roles of lipid oxidation products and receptor activator of nuclear factor-κB signaling in atherosclerotic calcification.
Circulation research 2011;108(12):1482-93.
2011: Andrew P Sage; Jinxiu Lu; Elisa Atti; Sotirios Tetradis; Maria-Grazia Ascenzi; Douglas J Adams; Linda L Demer; Yin Tintut
Hyperlipidemia induces resistance to PTH bone anabolism in mice via oxidized lipids.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(6):1197-206.
2011: Chang Hyun Byon; Yong Sun; Jianfeng Chen; Kaiyu Yuan; Xia Mao; Jack M Heath; Peter G Anderson; Yin Tintut; Linda L Demer; Deli Wang; Yabing Chen
Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(6):1387-96.
2011: Yin Tintut; Linda Demer
The hemosteoblast: friend or foe?
Circulation research 2011;108(9):1038-9.
2011: Andrew P Sage; Jinxiu Lu; Yin Tintut; Linda L Demer
Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro.
Kidney international 2011;79(4):414-22.
2010: Lucia S Graham; Yin Tintut; Farhad Parhami; Christina M R Kitchen; Yevgeniv Ivanov; Sotirios Tetradis; Rita B Effros
Bone density and hyperlipidemia: the T-lymphocyte connection.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(11):2460-9.
2010: Wendy Tseng; Lucia S Graham; Yifan Geng; Aneela Reddy; Jinxiu Lu; Rita B Effros; Linda Demer; Yin Tintut
PKA-induced receptor activator of NF-kappaB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification.
The Journal of biological chemistry 2010;285(39):29925-31.
2010: Andrew P Sage; Yin Tintut; Linda L Demer
Regulatory mechanisms in vascular calcification.
Nature reviews. Cardiology 2010;7(9):528-36.
2010: Linda L Demer; Yin Tintut
The bone-vascular axis in chronic kidney disease.
Current opinion in nephrology and hypertension 2010;19(4):349-53.
2010: Wendy Tseng; Jinxiu Lu; Gail A Bishop; Andrew D Watson; Andrew P Sage; Linda Demer; Yin Tintut
Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids.
Journal of lipid research 2010;51(5):1010-6.
2009: Lucia S Graham; Farhad Parhami; Yin Tintut; Christina Kitchen; Linda L Demer; Rita B Effros
Oxidized lipids enhance RANKL production by T lymphocytes: implications for lipid-induced bone loss.
Clinical immunology (Orlando, Fla.) 2009;133(2):265-75.
2009: Tetsuya Hoshino; Lori A Chow; Jeffrey J Hsu; Alice A Perlowski; Moeen Abedin; Jonathan Tobis; Yin Tintut; Ajit Mal; William S Klug; Linda L Demer
Mechanical stress analysis of a rigid inclusion in distensible material: a model of atherosclerotic calcification and plaque vulnerability.
American journal of physiology. Heart and circulatory physiology 2009;297(2):H802-10.
2009: Linda L Demer; Yin Tintut
Mechanisms linking osteoporosis with cardiovascular calcification.
Current osteoporosis reports 2009;7(2):42-6.
2009: Andrew Sage; Yin Tintut; Alan Garfinkel; Linda Demer
Systems biology of vascular calcification.
Trends in cardiovascular medicine 2009;19(4):118-23.
2009: Jeffrey J Hsu; Jinxiu Lu; Michael S Huang; Yifan Geng; Andrew P Sage; Michelle N Bradley; Peter Tontonoz; Linda L Demer; Yin Tintut
T0901317, an LXR agonist, augments PKA-induced vascular cell calcification.
FEBS letters 2009;583(8):1344-8.
2008: Linda L Demer; Andrew P Sage; Yin Tintut
Nanoscale architecture in atherosclerotic calcification.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(11):1882-4.
2008: Michael S Huang; Jinxiu Lu; Yevgeniy Ivanov; Andrew P Sage; Wendy Tseng; Linda L Demer; Yin Tintut
Hyperlipidemia impairs osteoanabolic effects of PTH.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(10):1672-9.
2008: Michael S Huang; Andrew P Sage; Jinxiu Lu; Linda L Demer; Yin Tintut
Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification.
Biochemical and biophysical research communications 2008;374(3):553-8.
2008: Jeffrey J Hsu; Yin Tintut; Linda L Demer
Vitamin D and osteogenic differentiation in the artery wall.
Clinical journal of the American Society of Nephrology : CJASN 2008;3(5):1542-7.
2008: Linda L Demer; Yin Tintut
Vascular calcification: pathobiology of a multifaceted disease.
Circulation 2008;117(22):2938-48.
2008: Jeffrey J Hsu; Yin Tintut; Linda L Demer
Murine models of atherosclerotic calcification.
Current drug targets 2008;9(3):224-8.
2008: Linda L Demer; Yin Tintut
A matter of degree: a commentary on "Influence of oxidized low-density lipoproteins (LDL) on the viability of osteoblastic cells".
Free radical biology & medicine 2008;44(4):504-5.
2008: Sean Morony; Yin Tintut; Zina Zhang; Russell C Cattley; Gwyneth Van; Denise Dwyer; Marina Stolina; Paul J Kostenuik; Linda L Demer
Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice.
Circulation 2008;117(3):411-20.
2007: Yin Tintut; M Huang; J Lu; W Tseng; Alan Garfinkel; Linda L Demer
Vascular calcification.
Journal of musculoskeletal & neuronal interactions 2007;7(4):346.
2007: Michael S Huang; Sean Morony; Jinxiu Lu; Zina Zhang; Olga Bezouglaia; Wendy Tseng; Sotirios Tetradis; Linda L Demer; Yin Tintut
Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts.
The Journal of biological chemistry 2007;282(29):21237-43.
2007: Iris Z Jaffe; Yin Tintut; Brenna G Newfell; Linda L Demer; Michael Mendelsohn
Mineralocorticoid receptor activation promotes vascular cell calcification.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):799-805.
2006: Yin Tintut; Linda L Demer
Role of osteoprotegerin and its ligands and competing receptors in atherosclerotic calcification.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2006;54(7):395-401.
2006: Tiantian C Lin; Yin Tintut; Althea Lyman; Wendy Mack; Linda L Demer; Tzung K Hsiai
Mechanical response of a calcified plaque model to fluid shear force.
Annals of biomedical engineering 2006;34(10):1535-41.
2006: Linda L Demer; Yin Tintut
Pitting phosphate transport inhibitors against vascular calcification.
Circulation research 2006;98(7):857-9.
2006: Moeen Abedin; Jina Lim; T B Tang; D Park; Linda L Demer; Yin Tintut
N-3 fatty acids inhibit vascular calcification via the p38-mitogen-activated protein kinase and peroxisome proliferator-activated receptor-gamma pathways.
Circulation research 2006;98(6):727-9.
2005: Yin Tintut; Moeen Abedin; John Cho; Andrea Choe; Jina Lim; Linda L Demer
Regulation of RANKL-induced osteoclastic differentiation by vascular cells.
Journal of molecular and cellular cardiology 2005;39(2):389-93.
2005: Linda L Demer; Yin Tintut
Return to ectopia: stem cells in the artery wall.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(7):1307-8.
2005: Kristen Radcliff; Tri-Bang Tang; Jina Lim; Zina Zhang; Moeen Abedin; Linda L Demer; Yin Tintut
Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways.
Circulation research 2005;96(4):398-400.
2004: Moeen Abedin; Yin Tintut; Linda L Demer
Mesenchymal stem cells and the artery wall.
Circulation research 2004;95(7):671-6.
2004: Moeen Abedin; Yin Tintut; Linda L Demer
Vascular calcification: mechanisms and clinical ramifications.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(7):1161-70.
2004: Alan Garfinkel; Yin Tintut; Danny Petrasek; Kristina Boström; Linda L Demer
Pattern formation by vascular mesenchymal cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9247-50.
2004: Yin Tintut; Sean Morony; Linda L Demer
Hyperlipidemia promotes osteoclastic potential of bone marrow cells ex vivo.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(2):e6-10.
2003: Yin Tintut; Zeni Alfonso; Trishal Saini; Kristen Radcliff; Karol Watson; Kristina Boström; Linda L Demer
Multilineage potential of cells from the artery wall.
Circulation 2003;108(20):2505-10.
2003: Linda L Demer; Yin Tintut
Mineral exploration: search for the mechanism of vascular calcification and beyond: the 2003 Jeffrey M. Hoeg Award lecture.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(10):1739-43.
2003: Nilam Mody; Yin Tintut; Kristen Radcliff; Linda L Demer
Vascular calcification and its relation to bone calcification: possible underlying mechanisms.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2003;10(2):177-83.
2002: Farhad Parhami; Nilam Mody; Nima M Gharavi; Alex J Ballard; Yin Tintut; Linda L Demer
Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(11):1997-2003.
2002: Farhad Parhami; Benjamin Basseri; Jason Hwang; Yin Tintut; Linda L Demer
High-density lipoprotein regulates calcification of vascular cells.
Circulation research 2002;91(7):570-6.
2002: Linda L Demer; Yin Tintut; Farhad Parhami
Novel mechanisms in accelerated vascular calcification in renal disease patients.
Current opinion in nephrology and hypertension 2002;11(4):437-43.
2002: Yin Tintut; Farhad Parhami; Anastasia Tsingotjidou; Sotirios Tetradis; Mary Territo; Linda L Demer
8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway.
The Journal of biological chemistry 2002;277(16):14221-6.
2002: Yin Tintut; Jignesh Patel; Mary Territo; Trishal Saini; Farhad Parhami; Linda L Demer
Monocyte/macrophage regulation of vascular calcification in vitro.
Circulation 2002;105(5):650-5.
2001: Yin Tintut; Linda L Demer
Recent advances in multifactorial regulation of vascular calcification.
Current opinion in lipidology 2001;12(5):555-60.
2001: Farhad Parhami; Yin Tintut; A Ballard; Alan M Fogelman; Linda L Demer
Leptin enhances the calcification of vascular cells: artery wall as a target of leptin.
Circulation research 2001;88(9):954-60.
2001: Farhad Parhami; Yin Tintut; Jignesh K Patel; Nilam Mody; A Hemmat; Linda L Demer
Regulation of vascular calcification in atherosclerosis.
Zeitschrift für Kardiologie 2001;90 Suppl 3():27-30.
2001: Farhad Parhami; Yin Tintut; W G Beamer; Nima M Gharavi; W Goodman; Linda L Demer
Atherogenic high-fat diet reduces bone mineralization in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(1):182-8.
2000: Yin Tintut; Jignesh Patel; Farhad Parhami; Linda L Demer
Tumor necrosis factor-alpha promotes in vitro calcification of vascular cells via the cAMP pathway.
Circulation 2000;102(21):2636-42.
2000: Kristina Boström; Yin Tintut; S C Kao; W P Stanford; Linda L Demer
HOXB7 overexpression promotes differentiation of C3H10T1/2 cells to smooth muscle cells.
Journal of cellular biochemistry 2000;78(2):210-21.
1999: Farhad Parhami; SM Jackson; Yin Tintut; Van H Le; J P Balucan; Mary Territo; Linda L Demer
Atherogenic diet and minimally oxidized low density lipoprotein inhibit osteogenic and promote adipogenic differentiation of marrow stromal cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(12):2067-78.
1999: Yin Tintut; Farhad Parhami; Van H Le; G Karsenty; Linda L Demer
Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation.
The Journal of biological chemistry 1999;274(41):28875-9.
1999: Linda L Demer; Yin Tintut
Osteopontin. Between a rock and a hard plaque.
Circulation research 1999;84(2):250-2.
1998: Yin Tintut; Farhad Parhami; Kristina Boström; SM Jackson; Linda L Demer
cAMP stimulates osteoblast-like differentiation of calcifying vascular cells. Potential signaling pathway for vascular calcification.
The Journal of biological chemistry 1998;273(13):7547-53.
1997: Farhad Parhami; A D Morrow; J Balucan; Norbert Leitinger; Andrew D Watson; Yin Tintut; Judith A Berliner; Linda L Demer
Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(4):680-7.
1995: Yin Tintut; J T Wang; Jay D Gralla
Abortive cycling and the release of polymerase for elongation at the sigma 54-dependent glnAp2 promoter.
The Journal of biological chemistry 1995;270(41):24392-8.
1995: Yin Tintut; Jay D Gralla
PCR mutagenesis identifies a polymerase-binding sequence of sigma 54 that includes a sigma 70 homology region.
Journal of bacteriology 1995;177(20):5818-25.
1995: Yin Tintut; J T Wang; Jay D Gralla
A novel bacterial transcription cycle involving sigma 54.
Genes & development 1995;9(18):2305-13.
1994: Yin Tintut; C Wong; Y Jiang; M Hsieh; Jay D Gralla
RNA polymerase binding using a strongly acidic hydrophobic-repeat region of sigma 54.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2120-4.
1994: C Wong; Yin Tintut; Jay D Gralla
The domain structure of sigma 54 as determined by analysis of a set of deletion mutants.
Journal of molecular biology 1994;236(1):81-90.
1994: M Hsieh; Yin Tintut; Jay D Gralla
Functional roles for the glutamines within the glutamine-rich region of the transcription factor sigma 54.
The Journal of biological chemistry 1994;269(1):373-8.