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Michael Tisdale

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Steven T Russell; Michael J Tisdale
Role of β-adrenergic receptors in the oral activity of zinc-α2-glycoprotein (ZAG).
K A Mirza; S M Wyke; Michael J Tisdale
Attenuation of muscle atrophy by an N-terminal peptide of the receptor for proteolysis-inducing factor (PIF).
Steven T Russell; Michael J Tisdale
Studies on the anti-obesity activity of zinc-α2-glycoprotein in the rat.

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All Publications

2012: Steven T Russell; Michael J Tisdale
Role of β-adrenergic receptors in the oral activity of zinc-α2-glycoprotein (ZAG).
Endocrinology 2012;153(10):4696-704.
2011: K A Mirza; S M Wyke; Michael J Tisdale
Attenuation of muscle atrophy by an N-terminal peptide of the receptor for proteolysis-inducing factor (PIF).
British journal of cancer 2011;105(1):83-8.
2011: Steven T Russell; Michael J Tisdale
Studies on the anti-obesity activity of zinc-α2-glycoprotein in the rat.
International journal of obesity (2005) 2011;35(5):658-65.
2011: Steven T Russell; Michael J Tisdale
Studies on the antiobesity effect of zinc-α2-glycoprotein in the ob/ob mouse.
International journal of obesity (2005) 2011;35(3):345-54.
2010: Steven T Russell; Michael J Tisdale
Mechanism of attenuation of skeletal muscle atrophy by zinc-alpha2-glycoprotein.
Endocrinology 2010;151(10):4696-704.
2010: Michael J Tisdale
Reversing cachexia.
Cell 2010;142(4):511-2.
2010: Helen L Eley; Steven T Russell; Michael J Tisdale
Mechanism of activation of dsRNA-dependent protein kinase (PKR) in muscle atrophy.
Cellular signalling 2010;22(5):783-90.
2010: Michael J Tisdale
Are tumoral factors responsible for host tissue wasting in cancer cachexia?
Future oncology (London, England) 2010;6(4):503-13.
2010: Steven T Russell; P M A Siren; M J Siren; Michael J Tisdale
The role of zinc in the anti-tumour and anti-cachectic activity of D-myo-inositol 1,2,6-triphosphate.
British journal of cancer 2010;102(5):833-6.
2010: Steven T Russell; Michael J Tisdale
Antidiabetic properties of zinc-alpha2-glycoprotein in ob/ob mice.
Endocrinology 2010;151(3):948-57.
2010: Michael J Tisdale
Cancer cachexia.
Current opinion in gastroenterology 2010;26(2):146-51.
2010: Steven T Russell; Pontus M A Siren; Matti J Siren; Michael J Tisdale
Mechanism of attenuation of protein loss in murine C2C12 myotubes by D-myo-inositol 1,2,6-triphosphate.
Experimental cell research 2010;316(2):286-95.
2009: Michael J Tisdale
Zinc-alpha2-glycoprotein in cachexia and obesity.
Current opinion in supportive and palliative care 2009;3(4):288-93.
2009: Steven T Russell; Michael J Tisdale
Mechanism of attenuation by beta-hydroxy-beta-methylbutyrate of muscle protein degradation induced by lipopolysaccharide.
Molecular and cellular biochemistry 2009;330(1-2):171-9.
2009: Steven T Russell; P M A Siren; M J Siren; Michael J Tisdale
Attenuation of skeletal muscle atrophy in cancer cachexia by D-myo-inositol 1,2,6-triphosphate.
Cancer chemotherapy and pharmacology 2009;64(3):517-27.
2009: Helen L Eley; Pria S McDonald; Steven T Russell; Michael J Tisdale
Inhibition of activation of dsRNA-dependent protein kinase and tumour growth inhibition.
Cancer chemotherapy and pharmacology 2009;63(4):651-9.
2009: Steven T Russell; Seema Rajani; Raj S Dhadda; Michael J Tisdale
Mechanism of induction of muscle protein loss by hyperglycaemia.
Experimental cell research 2009;315(1):16-25.
2008: Helen L Eley; Steven T Russell; Michael J Tisdale
Attenuation of depression of muscle protein synthesis induced by lipopolysaccharide, tumor necrosis factor, and angiotensin II by beta-hydroxy-beta-methylbutyrate.
American journal of physiology. Endocrinology and metabolism 2008;295(6):E1409-16.
2008: Helen L Eley; Steven T Russell; Michael J Tisdale
Mechanism of attenuation of muscle protein degradation induced by tumor necrosis factor-alpha and angiotensin II by beta-hydroxy-beta-methylbutyrate.
American journal of physiology. Endocrinology and metabolism 2008;295(6):E1417-26.
2008: Jwan Khal; Michael J Tisdale
Downregulation of muscle protein degradation in sepsis by eicosapentaenoic acid (EPA).
Biochemical and biophysical research communications 2008;375(2):238-40.
2008: Helen L Eley; Steven T Russell; Michael J Tisdale
Role of the dsRNA-dependent protein kinase (PKR) in the attenuation of protein loss from muscle by insulin and insulin-like growth factor-I (IGF-I).
Molecular and cellular biochemistry 2008;313(1-2):63-9.
2008: Steven T Russell; Helen L Eley; Stacey M Wyke; Michael J Tisdale
Involvement of phosphoinositide 3-kinase and Akt in the induction of muscle protein degradation by proteolysis-inducing factor.
The Biochemical journal 2008;409(3):751-9.
2008: Helen L Eley; R J E Skipworth; D A C Deans; Kenneth C H Fearon; Michael J Tisdale
Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2alpha may signal skeletal muscle atrophy in weight-losing cancer patients.
British journal of cancer 2008;98(2):443-9.
2008: D A C Deans; Stephen Wigmore; H Gilmour; Michael J Tisdale; Kenneth C H Fearon; James A Ross
Reply: Expression of the proteolysis-inducing factor core-peptide mRNA is upregulated in both tumour and adjacent normal tissue in gastrooesophageal malignancy.
British journal of cancer 2008;98(1):243.
2007: Penio T Todorov; Stacey M Wyke; Michael J Tisdale
Identification and characterization of a membrane receptor for proteolysis-inducing factor on skeletal muscle.
Cancer research 2007;67(23):11419-27.
2007: Helen L Eley; Steven T Russell; Michael J Tisdale
Effect of branched-chain amino acids on muscle atrophy in cancer cachexia.
The Biochemical journal 2007;407(1):113-20.
2007: Helen L Eley; Steven T Russell; Jeffrey H Baxter; Pradip Mukerji; Michael J Tisdale
Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli.
American journal of physiology. Endocrinology and metabolism 2007;293(4):E923-31.
2007: Steven T Russell; Helen L Eley; Michael J Tisdale
Role of reactive oxygen species in protein degradation in murine myotubes induced by proteolysis-inducing factor and angiotensin II.
Cellular signalling 2007;19(8):1797-806.
2007: Steven T Russell; Helen L Eley; Michael J Tisdale
Mechanism of attenuation of angiotensin-II-induced protein degradation by insulin-like growth factor-I (IGF-I).
Cellular signalling 2007;19(7):1583-95.
2007: Helen L Eley; Steven T Russell; Michael J Tisdale
Attenuation of muscle atrophy in a murine model of cachexia by inhibition of the dsRNA-dependent protein kinase.
British journal of cancer 2007;96(8):1216-22.
2007: Helen L Eley; Michael J Tisdale
Skeletal muscle atrophy, a link between depression of protein synthesis and increase in degradation.
The Journal of biological chemistry 2007;282(10):7087-97.
2006: Ameek S Bhogal; Maria L Lorite; Michael J Tisdale
Changes in nucleic acid and protein levels in atrophying skeletal muscle in cancer cachexia.
Anticancer research 2006;26(6B):4149-54.
2006: Kenneth C H Fearon; Matthew D Barber; Alastair G W Moses; Sam H Ahmedzai; Gillian S Taylor; Michael J Tisdale; Gordon D Murray
Double-blind, placebo-controlled, randomized study of eicosapentaenoic acid diester in patients with cancer cachexia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(21):3401-7.
2006: Steven T Russell; Stacey M Wyke; Michael J Tisdale
Mechanism of induction of muscle protein degradation by angiotensin II.
Cellular signalling 2006;18(7):1087-96.
2006: Stacey M Wyke; Michael J Tisdale
Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin-proteasome proteolytic pathway.
Life sciences 2006;78(25):2898-910.
2006: Michael J Tisdale
Clinical anticachexia treatments.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2006;21(2):168-74.
2006: Steven T Russell; Paul M Sanders; Michael J Tisdale
Angiotensin II directly inhibits protein synthesis in murine myotubes.
Cancer letters 2006;231(2):290-4.
2005: Jwan Khal; Stacey M Wyke; Steven T Russell; Anna V Hine; Michael J Tisdale
Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia.
British journal of cancer 2005;93(7):774-80.
2005: Michael J Tisdale
Molecular pathways leading to cancer cachexia.
Physiology (Bethesda, Md.) 2005;20():340-8.
2005: Jwan Khal; Anna V Hine; Kenneth C H Fearon; Cornelis H C Dejong; Michael J Tisdale
Increased expression of proteasome subunits in skeletal muscle of cancer patients with weight loss.
The international journal of biochemistry & cell biology 2005;37(10):2196-206.
2005: Paul M Sanders; Steven T Russell; Michael J Tisdale
Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia.
British journal of cancer 2005;93(4):425-34.
2005: Helen J Smith; Jwan Khal; Michael J Tisdale
Downregulation of ubiquitin-dependent protein degradation in murine myotubes during hyperthermia by eicosapentaenoic acid.
Biochemical and biophysical research communications 2005;332(1):83-8.
2005: Steven T Russell; Michael J Tisdale
Effect of eicosapentaenoic acid (EPA) on expression of a lipid mobilizing factor in adipose tissue in cancer cachexia.
Prostaglandins, leukotrienes, and essential fatty acids 2005;72(6):409-14.
2005: Michael J Tisdale
The ubiquitin-proteasome pathway as a therapeutic target for muscle wasting.
The journal of supportive oncology 2005;3(3):209-17.
2005: Steven T Russell; Michael J Tisdale
The role of glucocorticoids in the induction of zinc-alpha2-glycoprotein expression in adipose tissue in cancer cachexia.
British journal of cancer 2005;92(5):876-81.
2005: Stacey M Wyke; Michael J Tisdale
NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle.
British journal of cancer 2005;92(4):711-21.
2005: Anita Chand; Stacey M Wyke; Michael J Tisdale
Effect of cancer cachexia on the activity of tripeptidyl-peptidase II in skeletal muscle.
Cancer letters 2005;218(2):215-22.
2005: Helen J Smith; Pradip Mukerji; Michael J Tisdale
Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle loss.
Cancer research 2005;65(1):277-83.
2005: Stacey M Wyke; Jwan Khal; Michael J Tisdale
Signalling pathways in the induction of proteasome expression by proteolysis-inducing factor in murine myotubes.
Cellular signalling 2005;17(1):67-75.
2004: S A Beck; Michael J Tisdale
Effect of cancer cachexia on triacylglycerol/fatty acid substrate cycling in white adipose tissue.
Lipids 2004;39(12):1187-9.
2004: Helen J Smith; Stacey M Wyke; Michael J Tisdale
Mechanism of the attenuation of proteolysis-inducing factor stimulated protein degradation in muscle by beta-hydroxy-beta-methylbutyrate.
Cancer research 2004;64(23):8731-5.
2004: Michael J Tisdale
Tumor-host interactions.
Journal of cellular biochemistry 2004;93(5):871-7.
2004: Stacey M Wyke; Steven T Russell; Michael J Tisdale
Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation.
British journal of cancer 2004;91(9):1742-50.
2004: Michael P Wynter; Steven T Russell; Michael J Tisdale
Effect of n-3 fatty acids on the antitumour effects of cytotoxic drugs.
In vivo (Athens, Greece) 2004;18(5):543-7.
2004: Eric Lattmann; Derek Kinchington; Simon Dunn; Harjit Singh; Washington O Ayuko; Michael J Tisdale
Cytotoxicity of 3,4-dihalogenated 2(5H)-furanones.
The Journal of pharmacy and pharmacology 2004;56(9):1163-70.
2004: Paul M Sanders; Michael J Tisdale
Effect of zinc-alpha2-glycoprotein (ZAG) on expression of uncoupling proteins in skeletal muscle and adipose tissue.
Cancer letters 2004;212(1):71-81.
2004: Michael J Tisdale
Cancer cachexia.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2004;389(4):299-305.
2004: Helen J Smith; N A Greenberg; Michael J Tisdale
Effect of eicosapentaenoic acid, protein and amino acids on protein synthesis and degradation in skeletal muscle of cachectic mice.
British journal of cancer 2004;91(2):408-12.
2004: Helen J Smith; Stacey M Wyke; Michael J Tisdale
Role of protein kinase C and NF-kappaB in proteolysis-inducing factor-induced proteasome expression in C(2)C(12) myotubes.
British journal of cancer 2004;90(9):1850-7.
2004: Kejun Zhao; Yongfeng Wang; Linxiang Zhao; Zhizhong Ji; Dan Li; Michael J Tisdale; Carl H Schwalbe
Synthesis and cytotoxicity of a novel 1-alkylaminomethyl-2,4-diaryl-butadiene-1,3 fragment integrated within cyclohex(pent)enes.
Farmaco (Società chimica italiana : 1989) 2004;59(5):373-9.
2004: Paul M Sanders; Michael J Tisdale
Role of lipid-mobilising factor (LMF) in protecting tumour cells from oxidative damage.
British journal of cancer 2004;90(6):1274-8.
2004: Steven T Russell; Thomas P Zimmerman; Barbara A Domin; Michael J Tisdale
Induction of lipolysis in vitro and loss of body fat in vivo by zinc-alpha2-glycoprotein.
Biochimica et biophysica acta 2004;1636(1):59-68.
2003: Helen J Smith; Michael J Tisdale
Signal transduction pathways involved in proteolysis-inducing factor induced proteasome expression in murine myotubes.
British journal of cancer 2003;89(9):1783-8.
2003: Kenneth C H Fearon; M F Von Meyenfeldt; Alastair G W Moses; R Van Geenen; A Roy; D J Gouma; A Giacosa; A Van Gossum; J Bauer; Matthew D Barber; N K Aaronson; Anne C Voss; Michael J Tisdale
Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial.
Gut 2003;52(10):1479-86.
2003: AS Whitehouse; Michael J Tisdale
Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB.
British journal of cancer 2003;89(6):1116-22.
2003: Michael J Tisdale
Pathogenesis of cancer cachexia.
The journal of supportive oncology 2003;1(3):159-68.
2003: Eric Lattmann; Washington O Ayuko; Derek Kinchinaton; Christopher A Langley; Harjit Singh; Leila Karimi; Michael J Tisdale
Synthesis and evaluation of 5-arylated 2(5H)-furanones and 2-arylated pyridazin-3(2H)-ones as anti-cancer agents.
The Journal of pharmacy and pharmacology 2003;55(9):1259-65.
2003: AS Whitehouse; Jwan Khal; Michael J Tisdale
Induction of protein catabolism in myotubes by 15(S)-hydroxyeicosatetraenoic acid through increased expression of the ubiquitin-proteasome pathway.
British journal of cancer 2003;89(4):737-45.
2003: Julie Simpson; Rebecca Forrester; Michael J Tisdale; david billington; Daniel L Rathbone
Effect of catechol derivatives on cell growth and lipoxygenase activity.
Bioorganic & medicinal chemistry letters 2003;13(15):2435-9.
2003: Helen J Smith; Michael J Tisdale
Induction of apoptosis by a cachectic-factor in murine myotubes and inhibition by eicosapentaenoic acid.
Apoptosis : an international journal on programmed cell death 2003;8(2):161-9.
2003: Michael J Tisdale
The 'cancer cachectic factor'.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2003;11(2):73-8.
2002: Michael J Tisdale
Cachexia in cancer patients.
Nature reviews. Cancer 2002;2(11):862-71.
2002: Steven T Russell; Michael J Tisdale
Effect of a tumour-derived lipid-mobilising factor on glucose and lipid metabolism in vivo.
British journal of cancer 2002;87(5):580-4.
2002: Michael J Tisdale
Biochemical mechanisms of cellular catabolism.
Current opinion in clinical nutrition and metabolic care 2002;5(4):401-5.
2002: Steven T Russell; K Hirai; Michael J Tisdale
Role of beta3-adrenergic receptors in the action of a tumour lipid mobilizing factor.
British journal of cancer 2002;86(3):424-8.
2001: B Islam-Ali; S Khan; S A Price; Michael J Tisdale
Modulation of adipocyte G-protein expression in cancer cachexia by a lipid-mobilizing factor (LMF).
British journal of cancer 2001;85(5):758-63.
2001: Maria-Jose Lorite; Helen J Smith; J A Arnold; A Morris; Michael G Thompson; Michael J Tisdale
Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF).
British journal of cancer 2001;85(2):297-302.
2001: AS Whitehouse; Michael J Tisdale
Downregulation of ubiquitin-dependent proteolysis by eicosapentaenoic acid in acute starvation.
Biochemical and biophysical research communications 2001;285(3):598-602.
2001: B S Islam-Ali; Michael J Tisdale
Effect of a tumour-produced lipid-mobilizing factor on protein synthesis and degradation.
British journal of cancer 2001;84(12):1648-55.
2001: Michael J Tisdale
Cancer anorexia and cachexia.
Nutrition (Burbank, Los Angeles County, Calif.) 2001;17(5):438-42.
2001: AS Whitehouse; Helen J Smith; J L Drake; Michael J Tisdale
Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid.
Cancer research 2001;61(9):3604-9.
2001: J E Belizário; Maria-Jose Lorite; Michael J Tisdale
Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia.
British journal of cancer 2001;84(8):1135-40.
2001: Michael J Tisdale
Loss of skeletal muscle in cancer: biochemical mechanisms.
Frontiers in bioscience : a journal and virtual library 2001;6():D164-74.
2001: Matthew D Barber; Kenneth C H Fearon; Michael J Tisdale; Donald C McMillan; James A Ross
Effect of a fish oil-enriched nutritional supplement on metabolic mediators in patients with pancreatic cancer cachexia.
Nutrition and cancer 2001;40(2):118-24.
2000: Michael J Tisdale
Metabolic abnormalities in cachexia and anorexia.
Nutrition (Burbank, Los Angeles County, Calif.) 2000;16(10):1013-4.
2000: Michael J Tisdale
Biomedicine. Protein loss in cancer cachexia.
Science (New York, N.Y.) 2000;289(5488):2293-4.
2000: HJ Hussey; Penio T Todorov; WN Field; N Inagaki; Y Tanaka; H Ishitsuka; Michael J Tisdale
Effect of a fluorinated pyrimidine on cachexia and tumour growth in murine cachexia models: relationship with a proteolysis inducing factor.
British journal of cancer 2000;83(1):56-62.
2000: HJ Hussey; Michael J Tisdale
Effect of the specific cyclooxygenase-2 inhibitor meloxicam on tumour growth and cachexia in a murine model.
International journal of cancer. Journal international du cancer 2000;87(1):95-100.
2000: Michael J Tisdale
Catabolism of skeletal muscle proteins and its reversal in cancer cachexia.
Nestlé Nutrition workshop series. Clinical & performance programme 2000;4():135-43; discussion 144-6.
2000: Stephen Wigmore; Matthew D Barber; James A Ross; Michael J Tisdale; Kenneth C H Fearon
Effect of oral eicosapentaenoic acid on weight loss in patients with pancreatic cancer.
Nutrition and cancer 2000;36(2):177-84.
2000: Stephen Wigmore; Penio T Todorov; Matthew D Barber; James A Ross; Michael J Tisdale; Kenneth C H Fearon
Characteristics of patients with pancreatic cancer expressing a novel cancer cachectic factor.
The British journal of surgery 2000;87(1):53-8.
1999: Helen J Smith; Maria-Jose Lorite; Michael J Tisdale
Effect of a cancer cachectic factor on protein synthesis/degradation in murine C2C12 myoblasts: modulation by eicosapentaenoic acid.
Cancer research 1999;59(21):5507-13.
1999: Matthew D Barber; James A Ross; Anne C Voss; Michael J Tisdale; Kenneth C H Fearon
The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer.
British journal of cancer 1999;81(1):80-6.
1999: Penio T Todorov; WN Field; Michael J Tisdale
Role of a proteolysis-inducing factor (PIF) in cachexia induced by a human melanoma (G361).
British journal of cancer 1999;80(11):1734-7.
1999: HJ Hussey; Michael J Tisdale
Effect of a cachectic factor on carbohydrate metabolism and attenuation by eicosapentaenoic acid.
British journal of cancer 1999;80(8):1231-5.
1999: S Khan; Michael J Tisdale
Catabolism of adipose tissue by a tumour-produced lipid-mobilising factor.
International journal of cancer. Journal international du cancer 1999;80(3):444-7.
1999: Michael J Tisdale
Wasting in cancer.
The Journal of nutrition 1999;129(1S Suppl):243S-246S.
1998: S A Price; Michael J Tisdale
Mechanism of inhibition of a tumor lipid-mobilizing factor by eicosapentaenoic acid.
Cancer research 1998;58(21):4827-31.
1998: Maria-Jose Lorite; Michael G Thompson; J L Drake; G Carling; Michael J Tisdale
Mechanism of muscle protein degradation induced by a cancer cachectic factor.
British journal of cancer 1998;78(7):850-6.
1998: Kouzo Hirai; HJ Hussey; M D Barber; S A Price; Michael J Tisdale
Biological evaluation of a lipid-mobilizing factor isolated from the urine of cancer patients.
Cancer research 1998;58(11):2359-65.
1998: Penio T Todorov; T M McDevitt; D J Meyer; H Ueyama; I Ohkubo; Michael J Tisdale
Purification and characterization of a tumor lipid-mobilizing factor.
Cancer research 1998;58(11):2353-8.
1998: Michael J Tisdale
New cachexic factors.
Current opinion in clinical nutrition and metabolic care 1998;1(3):253-6.
1997: Michael J Tisdale
Isolation of a novel cancer cachectic factor.
The Proceedings of the Nutrition Society 1997;56(2):777-83.
1997: Penio T Todorov; M Deacon; Michael J Tisdale
Structural analysis of a tumor-produced sulfated glycoprotein capable of initiating muscle protein degradation.
The Journal of biological chemistry 1997;272(19):12279-88.
1997: Maria-Jose Lorite; P Cariuk; Michael J Tisdale
Induction of muscle protein degradation by a tumour factor.
British journal of cancer 1997;76(8):1035-40.
1997: P Cariuk; Maria-Jose Lorite; Penio T Todorov; WN Field; Stephen Wigmore; Michael J Tisdale
Induction of cachexia in mice by a product isolated from the urine of cachectic cancer patients.
British journal of cancer 1997;76(5):606-13.
1997: HJ Hussey; Michael J Tisdale
Mechanism of the anti-tumour effect of 2,3,5-trimethyl-6-(3-pyridylmethyl) 1,4-benzoquinone (CV-6504).
British journal of cancer 1997;75(6):845-9.
1997: Michael J Tisdale
Cancer cachexia: metabolic alterations and clinical manifestations.
Nutrition (Burbank, Los Angeles County, Calif.) 1997;13(1):1-7.
1996: HJ Hussey; Michael J Tisdale
Metabolism and pharmacokinetics of the anti-tumour agent 2,3,5-trimethyl-6-(3-pyridylmethyl)1,4-benzoquinone (CV-6504).
British journal of cancer 1996;74(9):1349-53.
1996: HJ Hussey; Michael J Tisdale
Inhibition of tumour growth by lipoxygenase inhibitors.
British journal of cancer 1996;74(5):683-7.
1996: HJ Hussey; M C Bibby; Michael J Tisdale
Novel anti-tumour activity of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4- benzoquinone (CV-6504) against established murine adenocarcinomas (MAC).
British journal of cancer 1996;73(10):1187-92.
1996: Penio T Todorov; T M McDevitt; P Cariuk; B Coles; M Deacon; Michael J Tisdale
Induction of muscle protein degradation and weight loss by a tumor product.
Cancer research 1996;56(6):1256-61.
1996: Michael J Tisdale; T M McDevitt; Penio T Todorov; P Cariuk
Catabolic factors in cancer cachexia.
In vivo (Athens, Greece) 1996;10(2):131-6.
1996: Michael J Tisdale
Inhibition of lipolysis and muscle protein degradation by EPA in cancer cachexia.
Nutrition (Burbank, Los Angeles County, Calif.) 1996;12(1 Suppl):S31-3.
1995: A S Clark; B Deans; Malcolm F G Stevens; Michael J Tisdale; R T Wheelhouse; B J Denny; John A Hartley
Antitumor imidazotetrazines. 32. Synthesis of novel imidazotetrazinones and related bicyclic heterocycles to probe the mode of action of the antitumor drug temozolomide.
Journal of medicinal chemistry 1995;38(9):1493-504.
1995: T M McDevitt; Penio T Todorov; S A Beck; S H Khan; Michael J Tisdale
Purification and characterization of a lipid-mobilizing factor associated with cachexia-inducing tumors in mice and humans.
Cancer research 1995;55(7):1458-63.
1994: E A Hudson; Michael J Tisdale
Comparison of the effectiveness of eicosapentaenoic acid administered as either the free acid or ethyl ester as an anticachectic and antitumour agent.
Prostaglandins, leukotrienes, and essential fatty acids 1994;51(2):141-5.
1994: HJ Hussey; Michael J Tisdale
Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo.
British journal of cancer 1994;70(1):6-10.
1994: E A Hudson; Michael J Tisdale
Alterations in plasma and tumour levels of fatty acids with weight loss in an experimental cachexia model.
Prostaglandins, leukotrienes, and essential fatty acids 1994;50(5):229-34.
1994: Michael J Tisdale; S A Beck; E A Hudson
Effects of eicosapentaenoic acid on tumour growth and cachexia in mouse colon cancer.
World review of nutrition and dietetics 1994;76():86-8.
1993: K L Smith; Michael J Tisdale
Mechanism of muscle protein degradation in cancer cachexia.
British journal of cancer 1993;68(2):314-8.
1993: E A Hudson; S A Beck; Michael J Tisdale
Kinetics of the inhibition of tumour growth in mice by eicosapentaenoic acid-reversal by linoleic acid.
Biochemical pharmacology 1993;45(11):2189-94.
1993: Michael J Tisdale
Cancer cachexia.
Anti-cancer drugs 1993;4(2):115-25.
1993: K L Smith; Michael J Tisdale
Increased protein degradation and decreased protein synthesis in skeletal muscle during cancer cachexia.
British journal of cancer 1993;67(4):680-5.
1993: Michael J Tisdale
Mechanism of lipid mobilization associated with cancer cachexia: interaction between the polyunsaturated fatty acid, eicosapentaenoic acid, and inhibitory guanine nucleotide-regulatory protein.
Prostaglandins, leukotrienes, and essential fatty acids 1993;48(1):105-9.
1992: T M McDevitt; Michael J Tisdale
Tumour-associated hypoglycaemia in a murine cachexia model.
British journal of cancer 1992;66(5):815-20.
1992: H D Mulligan; S M Mahony; J A Ross; Michael J Tisdale
Weight loss in a murine cachexia model is not associated with the cytokines tumour necrosis factor-alpha or interleukin-6.
Cancer letters 1992;65(3):239-43.
1992: H D Mulligan; S A Beck; Michael J Tisdale
Lipid metabolism in cancer cachexia.
British journal of cancer 1992;66(1):57-61.
1992: B Deans; Michael J Tisdale
Antitumour imidazotetrazines XXVIII 3-methyladenine DNA glycosylase activity in cell lines sensitive and resistant to temozolomide.
Cancer letters 1992;63(2):151-7.
1992: K L Smith; F S Steven; Michael J Tisdale
Observations on the inhibition of serum and cell surface enzymes by eicosapentaenoic acid.
Journal of enzyme inhibition 1992;6(4):303-15.
1991: H D Mulligan; Michael J Tisdale
Effect of the lipid-lowering agent bezafibrate on tumour growth rate in vivo.
British journal of cancer 1991;64(6):1035-8.
1991: S A Beck; K L Smith; Michael J Tisdale
Anticachectic and antitumor effect of eicosapentaenoic acid and its effect on protein turnover.
Cancer research 1991;51(22):6089-93.
1991: H D Mulligan; Michael J Tisdale
Metabolic substrate utilization by tumour and host tissues in cancer cachexia.
The Biochemical journal 1991;277 ( Pt 2)():321-6.
1991: S A Beck; Michael J Tisdale
Lipid mobilising factors specifically associated with cancer cachexia.
British journal of cancer 1991;63(6):846-50.
1991: P A Hepburn; G P Margison; Michael J Tisdale
Enzymatic methylation of cytosine in DNA is prevented by adjacent O6-methylguanine residues.
The Journal of biological chemistry 1991;266(13):7985-7.
1991: H D Mulligan; Michael J Tisdale
Lipogenesis in tumour and host tissues in mice bearing colonic adenocarcinomas.
British journal of cancer 1991;63(5):719-22.
1991: S Briddon; S A Beck; Michael J Tisdale
Changes in activity of lipoprotein lipase, plasma free fatty acids and triglycerides with weight loss in a cachexia model.
Cancer letters 1991;57(1):49-53.
1991: P A Hepburn; Michael J Tisdale
Importance of the O6 position of guanine residues in the binding of DNA methylase to DNA.
Biochimica et biophysica acta 1991;1088(3):341-4.
1991: P A Hepburn; Michael J Tisdale
Antitumour imidazotetrazines--XXIV. Growth suppression by DNA from cells treated with imidazotetrazinones.
Biochemical pharmacology 1991;41(3):339-43.
1991: Michael J Tisdale; S A Beck
Inhibition of tumour-induced lipolysis in vitro and cachexia and tumour growth in vivo by eicosapentaenoic acid.
Biochemical pharmacology 1991;41(1):103-7.
1990: S A Beck; H D Mulligan; Michael J Tisdale
Lipolytic factors associated with murine and human cancer cachexia.
Journal of the National Cancer Institute 1990;82(24):1922-6.
1990: Michael J Tisdale
Newly identified factors that alter host metabolism in cancer cachexia.
Trends in pharmacological sciences 1990;11(12):473-5.
1990: S A Beck; P Groundwater; C Barton; Michael J Tisdale
Alterations in serum lipolytic activity of cancer patients with response to therapy.
British journal of cancer 1990;62(5):822-5.
1990: P Groundwater; S A Beck; C Barton; C Adamson; Ian Nicol Ferrier; Michael J Tisdale
Alteration of serum and urinary lipolytic activity with weight loss in cachectic cancer patients.
British journal of cancer 1990;62(5):816-21.
1990: S A Beck; Michael J Tisdale
Effect of megestrol acetate on weight loss induced by tumour necrosis factor alpha and a cachexia-inducing tumour (MAC16) in NMRI mice.
British journal of cancer 1990;62(3):420-4.
1990: Michael J Tisdale; J K Dhesi
Inhibition of weight loss by omega-3 fatty acids in an experimental cachexia model.
Cancer research 1990;50(16):5022-6.
1990: Michael J Tisdale; S A Beck
Cancer cachexia.
International journal of pancreatology : official journal of the International Association of Pancreatology 1990;7(1-3):141-50.
1990: S M Mahony; Michael J Tisdale
Metabolic effects of tumour necrosis factor alpha in NMRI mice.
British journal of cancer 1990;61(4):514-9.
1990: Michael J Tisdale
Metabolic effects in a murine cachexia model.
Biochemical Society transactions 1990;18(1):83-4.
1989: S A Beck; Michael J Tisdale
Nitrogen excretion in cancer cachexia and its modification by a high fat diet in mice.
Cancer research 1989;49(14):3800-4.
1989: S M Mahony; Michael J Tisdale
Role of prostaglandins in tumour necrosis factor induced weight loss.
British journal of cancer 1989;60(1):51-5.
1989: S M Mahony; Michael J Tisdale
Reversal of weight loss induced by tumour necrosis factor-alpha.
Cancer letters 1989;45(3):167-72.
1989: S A Beck; Michael J Tisdale
Effect of insulin on weight loss and tumour growth in a cachexia model.
British journal of cancer 1989;59(5):677-81.
1989: Michael J Tisdale
Antitumour imidazotetrazines--XVIII. Modification of the level of 5-methylcytosine in DNA by 3-substituted imidazotetrazinones.
Biochemical pharmacology 1989;38(7):1097-101.
1988: Michael J Tisdale; R A Brennan
A comparison of long-chain triglycerides and medium-chain triglycerides on weight loss and tumour size in a cachexia model.
British journal of cancer 1988;58(5):580-3.
1988: Michael J Tisdale; Y C Leung
Changes in host liver fatty acid synthase in tumour-bearing mice.
Cancer letters 1988;42(3):231-5.
1988: N I Hooper; Michael J Tisdale; Paul J Thornalley
Modification of the glyoxalase system in human HL60 promyelocytic leukaemia cells during differentiation to neutrophils in vitro.
Biochimica et biophysica acta 1988;966(3):362-9.
1988: S M Mahony; Michael J Tisdale
Induction of weight loss and metabolic alterations by human recombinant tumour necrosis factor.
British journal of cancer 1988;58(3):345-9.
1988: S M Mahony; S A Beck; Michael J Tisdale
Comparison of weight loss induced by recombinant tumour necrosis factor with that produced by a cachexia-inducing tumour.
British journal of cancer 1988;57(4):385-9.
1988: Michael J Tisdale
Antitumour imidazotetrazines and gene expression.
Acta oncologica (Stockholm, Sweden) 1988;27(5):511-6.
1988: Paul J Thornalley; Michael J Tisdale
Inhibition of proliferation of human promyelocytic leukaemia HL60 cells by S-D-lactoylglutathione in vitro.
Leukemia research 1988;12(11-12):897-904.
1987: S A Beck; Michael J Tisdale
Production of lipolytic and proteolytic factors by a murine tumor-producing cachexia in the host.
Cancer research 1987;47(22):5919-23.
1987: V L Bull; Michael J Tisdale
Antitumour imidazotetrazines--XVI. Macromolecular alkylation by 3-substituted imidazotetrazinones.
Biochemical pharmacology 1987;36(19):3215-20.
1987: N I Hooper; Michael J Tisdale; Paul J Thornalley
Glyoxalase activity during differentiation of human leukaemia cells in vitro.
Leukemia research 1987;11(12):1141-8.