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Andrew Tobin

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Chemicals & Drugs

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Publications

TOP 3
Kok-Choi Kong; Andrew B Tobin
The role of M(3)-muscarinic receptor signaling in insulin secretion.
Adrian J Butcher; Rudi Prihandoko; Kok-Choi Kong; Phillip McWilliams; Jennifer M Edwards; Andrew Bottrill; Sharad Mistry; Andrew B Tobin
Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.
Lev Solyakov; Divya Catherine Thomas; Andrew B Tobin; Abdirhaman Abdi; Shruti Agarwal; Mahmood M Alam; Andrew Bottrill; Yvan Bouza; Claudia Demarta; Dominique Dorin-Semblat; Sylvain Eschenlauer; Clare Fennell; Michele Graciotti; Jean Halbert; Zoe Holland; Selina Kern; Tenzing Lama; Sharad Mistry; Marie-Paule Nivez; Gabriele Pradel; Luc Reininger; Jean-Philippe Semblat; Pushkar Sharma; Audrey Sicard; Christian Doerig
Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum.

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All Publications

2011: Kok-Choi Kong; Andrew B Tobin
The role of M(3)-muscarinic receptor signaling in insulin secretion.
Communicative & integrative biology 2011;4(4):489-91.
2011: Adrian J Butcher; Rudi Prihandoko; Kok-Choi Kong; Phillip McWilliams; Jennifer M Edwards; Andrew Bottrill; Sharad Mistry; Andrew B Tobin
Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.
The Journal of biological chemistry 2011;286(13):11506-18.
2011: Lev Solyakov; Divya Catherine Thomas; Andrew B Tobin; Abdirhaman Abdi; Shruti Agarwal; Mahmood M Alam; Andrew Bottrill; Yvan Bouza; Claudia Demarta; Dominique Dorin-Semblat; Sylvain Eschenlauer; Clare Fennell; Michele Graciotti; Jean Halbert; Zoe Holland; Selina Kern; Tenzing Lama; Sharad Mistry; Marie-Paule Nivez; Gabriele Pradel; Luc Reininger; Jean-Philippe Semblat; Pushkar Sharma; Audrey Sicard; Christian Doerig
Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum.
Nature communications 2011;2():565.
2011: Adrian J Butcher; Andrew B Tobin; Kok-Choi Kong
Examining site-specific GPCR phosphorylation.
Methods in molecular biology (Clifton, N.J.) 2011;746():237-49.
2010: Kok-Choi Kong; Adrian J Butcher; Phillip McWilliams; David Jones; Jürgen Wess; Fadi F Hamdan; Tim Werry; Elizabeth M Rosethorne; Steven J Charlton; Sarah E Munson; Hannah A Cragg; Alison D Smart; Andrew B Tobin
M3-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(49):21181-6.
2010: Benoit Poulin; Adrian Butcher; Phillip McWilliams; Julie-Myrtille Bourgognon; Robert Pawlak; Kok-Choi Kong; Andrew Bottrill; Sharad Mistry; Jürgen Wess; Elizabeth M Rosethorne; Steven J Charlton; Andrew B Tobin
The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(20):9440-5.
2009: L Solyakov; E Sayan; Joan Riley; A Pointon; Andrew B Tobin
Regulation of p53 expression, phosphorylation and subcellular localization by a G-protein-coupled receptor.
Oncogene 2009;28(41):3619-30.
2009: Nisha Kurian; Caroline J Hall; Graeme F Wilkinson; Michael Sullivan; Andrew B Tobin; Gary B Willars
Full and partial agonists of muscarinic M3 receptors reveal single and oscillatory Ca2+ responses by beta 2-adrenoceptors.
The Journal of pharmacology and experimental therapeutics 2009;330(2):502-12.
2009: Adrian J Butcher; Ignacio Torrecilla; Kenneth W Young; Kok-Choi Kong; Sharad C Mistry; Andrew Bottrill; Andrew B Tobin
N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.
The Journal of biological chemistry 2009;284(25):17147-56.
2009: Andrew B Tobin
G-protein-coupled receptor structure: what can we learn?
F1000 biology reports 2009;1():11.
2008: Andrew B Tobin; Adrian J Butcher; Kok-Choi Kong
Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling.
Trends in pharmacological sciences 2008;29(8):413-20.
2008: Andrew B Tobin
G-protein-coupled receptor phosphorylation: where, when and by whom.
British journal of pharmacology 2008;153 Suppl 1():S167-76.
2007: S L Cockerill; Andrew B Tobin; Ignacio Torrecilla; Gary B Willars; Nicholas B Standen; John S Mitcheson
Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits.
The Journal of physiology 2007;581(Pt 2):479-93.
2007: Ignacio Torrecilla; Elizabeth J Spragg; Benoit Poulin; Phillip J McWilliams; Sharad C Mistry; Andree Blaukat; Andrew B Tobin
Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2.
The Journal of cell biology 2007;177(1):127-37.
2006: Ignacio Torrecilla; Andrew B Tobin
Co-ordinated covalent modification of G-protein coupled receptors.
Current pharmaceutical design 2006;12(14):1797-808.
2004: Lev Solyakov; Kelvin Cain; Beryl M Tracey; Rebekah Jukes; Andrew M Riley; Barry V L Potter; Andrew B Tobin
Regulation of casein kinase-2 (CK2) activity by inositol phosphates.
The Journal of biological chemistry 2004;279(42):43403-10.
2004: Catherine Vial; Andrew B Tobin; Richard J Evans
G-protein-coupled receptor regulation of P2X1 receptors does not involve direct channel phosphorylation.
The Biochemical journal 2004;382(Pt 1):101-10.
2004: David C Budd; Elizabeth J Spragg; Katie Ridd; Andrew B Tobin
Signalling of the M3-muscarinic receptor to the anti-apoptotic pathway.
The Biochemical journal 2004;381(Pt 1):43-9.
2004: Andrew B Tobin; Mark Wheatley
G-protein-coupled receptor phosphorylation and palmitoylation.
Methods in molecular biology (Clifton, N.J.) 2004;259():275-81.
2003: Andrew B Tobin; David C Budd
The anti-apoptotic response of the Gq/11-coupled muscarinic receptor family.
Biochemical Society transactions 2003;31(Pt 6):1182-5.
2003: David C Budd; John McDonald; Nita Emsley; Kelvin Cain; Andrew B Tobin
The C-terminal tail of the M3-muscarinic receptor possesses anti-apoptotic properties.
The Journal of biological chemistry 2003;278(21):19565-73.
2002: Andrew B Tobin
Are we beta-ARKing up the wrong tree? Casein kinase 1 alpha provides an additional pathway for GPCR phosphorylation.
Trends in pharmacological sciences 2002;23(7):337-43.
2001: J M Hilton; Markus Plomann; Brigitte Ritter; Jan Modregger; H N Freeman; J R Falck; U M Krishna; Andrew B Tobin
Phosphorylation of a synaptic vesicle-associated protein by an inositol hexakisphosphate-regulated protein kinase.
The Journal of biological chemistry 2001;276(19):16341-7.
2001: David C Budd; Gary B Willars; J E McDonald; Andrew B Tobin
Phosphorylation of the Gq/11-coupled m3-muscarinic receptor is involved in receptor activation of the ERK-1/2 mitogen-activated protein kinase pathway.
The Journal of biological chemistry 2001;276(7):4581-7.
2000: David C Budd; J E McDonald; Andrew B Tobin
Phosphorylation and regulation of a Gq/11-coupled receptor by casein kinase 1alpha.
The Journal of biological chemistry 2000;275(26):19667-75.
1999: David C Budd; R A John Challiss; Kenneth W Young; Andrew B Tobin
Cross talk between m3-muscarinic and beta(2)-adrenergic receptors at the level of receptor phosphorylation and desensitization.
Molecular pharmacology 1999;56(4):813-23.
1999: David C Budd; A Rae; Andrew B Tobin
Activation of the mitogen-activated protein kinase pathway by a Gq/11-coupled muscarinic receptor is independent of receptor internalization.
The Journal of biological chemistry 1999;274(18):12355-60.
1999: M G Waugh; R A John Challiss; G Berstein; Stefan R Nahorski; Andrew B Tobin
Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors.
The Biochemical journal 1999;338 ( Pt 1)():175-83.
1997: Andrew B Tobin; N F Totty; A E Sterlin; Stefan R Nahorski
Stimulus-dependent phosphorylation of G-protein-coupled receptors by casein kinase 1alpha.
The Journal of biological chemistry 1997;272(33):20844-9.
1997: Andrew B Tobin
Phosphorylation of phospholipase C-coupled receptors.
Pharmacology & therapeutics 1997;75(2):135-51.
1997: Andrew B Tobin
Protocols employed in the investigation of G protein-coupled receptor phosphorylation.
Methods in molecular biology (Clifton, N.J.) 1997;83():227-34.
1997: Stefan R Nahorski; Andrew B Tobin; Gary B Willars
Muscarinic M3 receptor coupling and regulation.
Life sciences 1997;60(13-14):1039-45.
1995: Andrew B Tobin; Gary B Willars; N T Burford; Stefan R Nahorski
Relationship between agonist binding, phosphorylation and immunoprecipitation of the m3-muscarinic receptor, and second messenger responses.
British journal of pharmacology 1995;116(2):1723-8.
1995: N T Burford; Andrew B Tobin; Stefan R Nahorski
Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells.
The Journal of pharmacology and experimental therapeutics 1995;274(1):134-42.
1995: N T Burford; Andrew B Tobin; Stefan R Nahorski
Coupling of muscarinic m1, m2 and m3 acetylcholine receptors, expressed in Chinese hamster ovary cells, to pertussis toxin-sensitive/insensitive guanine nucleotide-binding proteins.
European journal of pharmacology 1995;289(2):343-51.
1994: R J Wojcikiewicz; Andrew B Tobin; Stefan R Nahorski
Muscarinic receptor-mediated inositol 1,4,5-trisphosphate formation in SH-SY5Y neuroblastoma cells is regulated acutely by cytosolic Ca2+ and by rapid desensitization.
Journal of neurochemistry 1994;63(1):177-85.
1993: R J Wojcikiewicz; Andrew B Tobin; Stefan R Nahorski
Desensitization of cell signalling mediated by phosphoinositidase C.
Trends in pharmacological sciences 1993;14(7):279-85.
1993: Andrew B Tobin; Stefan R Nahorski
Rapid agonist-mediated phosphorylation of m3-muscarinic receptors revealed by immunoprecipitation.
The Journal of biological chemistry 1993;268(13):9817-23.
1992: Andrew B Tobin; David G Lambert; Stefan R Nahorski
Rapid desensitization of muscarinic m3 receptor-stimulated polyphosphoinositide responses.
Molecular pharmacology 1992;42(6):1042-8.