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Martin Tobin

Research Profile

Physiology

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Procedures

Disorders

Blood Pressure

Concepts & Ideas

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Publications

TOP 3
Shona M Kerr; Andrew Morris; Lee Murphy; Archie Campbell; Anna Dominiczak; Caroline Hayward; Cathy Jackson; Blair H Smith; Martin D Tobin; Louise V Wain; David J Porteous
Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study.
Tom R Gaunt; Jules C Hancox; Aroon D Hingorani; Steve E Humphries; Mika Kivimaki; Meena Kumari; Debbie A Lawlor; Peter W Macfarlane; Christopher P Nelson; Nilesh J Samani; Sonia Shah; Philippa J Talmud; Martin D Tobin; Maciej Tomaszewski; John Whittaker; Henggui Zhang; Ismail Adeniran; Antoinette Amuzu; Peter Braund; Paul R Burton; Juan P Casas; Fotios Drenos; Per Eriksson; Lasse Folkersen; Ian N M Day
Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.
L V Wain; M Soler Artigas; Martin D Tobin
What can genetics tell us about the cause of fixed airflow obstruction?

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All Publications

2013: Shona M Kerr; Andrew Morris; Lee Murphy; Archie Campbell; Anna Dominiczak; Caroline Hayward; Cathy Jackson; Blair H Smith; Martin D Tobin; Louise V Wain; David J Porteous
Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study.
BMC medical genetics 2013;14(1):38.
2012: Tom R Gaunt; Jules C Hancox; Aroon D Hingorani; Steve E Humphries; Mika Kivimaki; Meena Kumari; Debbie A Lawlor; Peter W Macfarlane; Christopher P Nelson; Nilesh J Samani; Sonia Shah; Philippa J Talmud; Martin D Tobin; Maciej Tomaszewski; John Whittaker; Henggui Zhang; Ismail Adeniran; Antoinette Amuzu; Peter Braund; Paul R Burton; Juan P Casas; Fotios Drenos; Per Eriksson; Lasse Folkersen; Ian N M Day
Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.
Circulation. Cardiovascular genetics 2012;5(6):630-8.
2012: L V Wain; M Soler Artigas; Martin D Tobin
What can genetics tell us about the cause of fixed airflow obstruction?
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2012;42(8):1176-82.
2012: Jenni Koskela; Mika Kähönen; Tiit Kööbi; Rami Lehtinen; Kari Niemelä; Tuomo Nieminen; Kjell C Nikus; Ilkka Pörsti; Nilesh J Samani; Martin D Tobin; Väinö Turjanmaa; Jari Viik; Terho Lehtimäki
Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing.
Scandinavian journal of clinical and laboratory investigation 2012;72(2):100-7.
2012: María Soler Artigas; Louise V Wain; Martin D Tobin
Genome-wide association studies in lung disease.
Thorax 2012;67(3):271-3, 280.
2011: Wibke Reinhard; Bernhard M Kaess; Radoslaw Debiec; Christopher P Nelson; Klaus Stark; Martin D Tobin; Peter W Macfarlane; Maciej Tomaszewski; Nilesh J Samani; Christian Hengstenberg
Heritability of early repolarization: a population-based study.
Circulation. Cardiovascular genetics 2011;4(2):134-8.
2011: Bernhard M Kaess; Maciej Tomaszewski; Peter Braund; Klaus Stark; Suzanne Rafelt; Marcus Fischer; Robert Hardwick; Christopher P Nelson; Radoslaw Debiec; Fritz Huber; Werner Kremer; Hans Robert Kalbitzer; Lynda M Rose; Daniel I Chasman; Jemma Hopewell; Robert Clarke; Paul R Burton; Martin D Tobin; Christian Hengstenberg; Nilesh J Samani
Large-scale candidate gene analysis of HDL particle features.
PloS one 2011;6(1):e14529.
2011: Louise V Wain; Martin D Tobin
Copy number variation.
Methods in molecular biology (Clifton, N.J.) 2011;713():167-83.
2010: Maciej Tomaszewski; Radoslaw Debiec; Peter Braund; Christopher P Nelson; Robert Hardwick; Paraskevi Christofidou; Matthew Denniff; Veryan Codd; Suzanne Rafelt; Pim van der Harst; Dawn Waterworth; Kijoung Song; Peter Vollenweider; Gerard Waeber; Ewa Zukowska-Szczechowska; Paul R Burton; Vincent Mooser; Fadi J Charchar; John R Thompson; Martin D Tobin; Nilesh J Samani
Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array.
Hypertension 2010;56(6):1069-76.
2010: Veryan Codd; Massimo Mangino; Pim van der Harst; Peter S Braund; Michael Kaiser; Alan J Beveridge; Suzanne Rafelt; Jasbir Moore; Chris Nelson; Nicole Soranzo; Guangju Zhai; Ana M Valdes; Hannah Blackburn; Irene Mateo Leach; Rudolf A de Boer; Alison H Goodall; Willem Ouwehand; Dirk J van Veldhuisen; Wiek H van Gilst; gerjan navis; Paul R Burton; Martin D Tobin; Alistair Hall; John R Thompson; Tim Spector; Abraham Aviv; Masayuki Kimura; Nilesh J Samani
Common variants near TERC are associated with mean telomere length.
Nature genetics 2010;42(3):197-9.
2009: Louise V Wain; John A L Armour; Martin D Tobin
Genomic copy number variation, human health, and disease.
Lancet 2009;374(9686):340-50.
2009: Louise V Wain; Inti Pedroso; John E Landers; Gerome Breen; Christopher E Shaw; P Nigel Leigh; Robert H Brown; Martin D Tobin; Ammar Al-Chalabi
The role of copy number variation in susceptibility to amyotrophic lateral sclerosis: genome-wide association study and comparison with published loci.
PloS one 2009;4(12):e8175.
2008: Tom M Palmer; John R Thompson; Martin D Tobin
Meta-analysis of Mendelian randomization studies incorporating all three genotypes.
Statistics in medicine 2008;27(30):6570-82.
2008: Martin D Tobin; Nicholas J Timpson; Louise V Wain; Susan Ring; Louise R Jones; Pauline M Emmett; Thomas M Palmer; Andrew R Ness; Nilesh J Samani; George Davey Smith; Paul R Burton
Common variation in the WNK1 gene and blood pressure in childhood: the Avon Longitudinal Study of Parents and Children.
Hypertension 2008;52(5):974-9.
2008: Nilesh J Samani; Peter Braund; Jeanette Erdmann; Anika Götz; Maciej Tomaszewski; Patrick Linsel-Nitschke; Cother Hajat; Massimo Mangino; Christian Hengstenberg; Klaus Stark; Andreas Ziegler; Mark Caulfield; Paul R Burton; Heribert Schunkert; Martin D Tobin
The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol.
Journal of molecular medicine (Berlin, Germany) 2008;86(11):1233-41.
2008: Martin D Tobin; Mika Kähönen; Peter Braund; Tuomo Nieminen; Cother Hajat; Maciej Tomaszewski; Jari Viik; Rami Lehtinen; G. Andre Ng; Peter W Macfarlane; Paul R Burton; Terho Lehtimäki; Nilesh J Samani
Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations.
International journal of epidemiology 2008;37(5):1132-41.
2008: Tom M Palmer; John R Thompson; Martin D Tobin; Nuala A Sheehan; Paul R Burton
Adjusting for bias and unmeasured confounding in Mendelian randomization studies with binary responses.
International journal of epidemiology 2008;37(5):1161-8.
2008: Nilesh J Samani; Olli T Raitakari; Kalle Sipilä; Martin D Tobin; Heribert Schunkert; Markus Juonala; Peter Braund; Jeanette Erdmann; Jorma Viikari; Leena Moilanen; Leena Taittonen; Antti Jula; Eero Jokinen; Tomi Laitinen; Nina Hutri-Kähönen; Markku S Nieminen; Y Antero Kesäniemi; Alistair Hall; Janne Hulkkonen; Mika Kähönen; Terho Lehtimäki
Coronary artery disease-associated locus on chromosome 9p21 and early markers of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(9):1679-83.
2008: Nuala A Sheehan; Vanessa Didelez; Paul R Burton; Martin D Tobin
Mendelian randomisation and causal inference in observational epidemiology.
PLoS medicine 2008;5(8):e177.
2008: Martin D Tobin; Maciej Tomaszewski; Peter S Braund; Cother Hajat; Stuart M Raleigh; Thomas M Palmer; Mark Caulfield; Paul R Burton; Nilesh J Samani
Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population.
Hypertension 2008;51(6):1658-64.
2007: Mary Dixon-Woods; Richard E Ashcroft; Clare J Jackson; Martin D Tobin; Joelle Kivits; Paul R Burton; Nilesh J Samani
Beyond "misunderstanding": written information and decisions about taking part in a genetic epidemiology study.
Social science & medicine (1982) 2007;65(11):2212-22.
2005: Martin D Tobin; Stuart M Raleigh; Stephen Newhouse; Peter Braund; Clare Bodycote; Jenny Ogleby; Deborah Cross; Jay Gracey; Saija Hayes; Terry Smith; Cathy Ridge; Mark Caulfield; Nuala A Sheehan; Patricia B Munroe; Paul R Burton; Nilesh J Samani
Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population.
Circulation 2005;112(22):3423-9.
2005: Martin D Tobin; Nuala A Sheehan; Katrina J Scurrah; Paul R Burton
Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure.
Statistics in medicine 2005;24(19):2911-35.
2005: Paul R Burton; Katrina J Scurrah; Martin D Tobin; Lyle Palmer
Covariance components models for longitudinal family data.
International journal of epidemiology 2005;34(5):1063-77; discussion 1077-9.
2005: Paul R Burton; Martin D Tobin; John L Hopper
Key concepts in genetic epidemiology.
Lancet 2005;366(9489):941-51.
2005: John R Thompson; Cosetta Minelli; Keith Abrams; Martin D Tobin; Richard D Riley
Meta-analysis of genetic studies using Mendelian randomization--a multivariate approach.
Statistics in medicine 2005;24(14):2241-54.
2004: Cosetta Minelli; John R Thompson; Martin D Tobin; Keith Abrams
An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization.
American journal of epidemiology 2004;160(5):445-52.
2004: Martin D Tobin; Peter Braund; Paul R Burton; John R Thompson; Richard Steeds; Kevin Channer; Suzanne Cheng; Klaus Lindpaintner; Nilesh J Samani
Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study.
European heart journal 2004;25(6):459-67.
2004: Martin D Tobin; Cosetta Minelli; Paul R Burton; John R Thompson
Commentary: development of Mendelian randomization: from hypothesis test to 'Mendelian deconfounding'.
International journal of epidemiology 2004;33(1):26-9.
2003: Katrina J Scurrah; Martin D Tobin; Paul R Burton
Longitudinal variance components models for systolic blood pressure, fitted using Gibbs sampling.
BMC genetics 2003;4 Suppl 1():S25.
2002: Martin D Tobin; J Milligan; R Shukla; B Crump; Paul R Burton
South Asian ethnicity and risk of childhood accidents: an ecological study at enumeration district level in Leicester.
Journal of public health medicine 2002;24(4):313-8.
1999: Martin D Tobin; C J Packham
Can primary care groups learn how to manage demand from fundholders? A study of fundholders in Nottingham.
The British journal of general practice : the journal of the Royal College of General Practitioners 1999;49(441):291-4.