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Giuseppe Tocchini-Valentini

Research Profile

Chemicals & Drugs

Concepts & Ideas

Anatomy

COS Cells

Procedures

X Ray Crystallography

Disorders

Sequence Deletion

Living Beings

Cercopithecus aethiops

Physiology

Phenomena

X-Ray Diffraction

Genes & Molecular Sequences

Molecular Structure

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Publications

TOP 3
Guy Eelen; Lieve Verlinden; Natacha Rochel; Frank Claessens; Pierre J De Clercq; Maurits Vandewalle; Giuseppe Tocchini-Valentini; Dino Moras; Roger Bouillon; Annemieke Verstuyf
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
Giuseppe Tocchini-Valentini; Natacha Rochel; Jean-Marie Wurtz; Dino Moras
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
Giuseppe Tocchini-Valentini; Natacha Rochel; Jean-Marie Wurtz; Andre Mitschler; Dino Moras
Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.

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All Publications

2005: Guy Eelen; Lieve Verlinden; Natacha Rochel; Frank Claessens; Pierre J De Clercq; Maurits Vandewalle; Giuseppe Tocchini-Valentini; Dino Moras; Roger Bouillon; Annemieke Verstuyf
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
Molecular pharmacology 2005;67(5):1566-73.
2004: Giuseppe Tocchini-Valentini; Natacha Rochel; Jean-Marie Wurtz; Dino Moras
Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
Journal of medicinal chemistry 2004;47(8):1956-61.
2001: Giuseppe Tocchini-Valentini; Natacha Rochel; Jean-Marie Wurtz; Andre Mitschler; Dino Moras
Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5491-6.
2001: Natacha Rochel; Giuseppe Tocchini-Valentini; Pascal F Egea; Katri S Juntunen; J M Garnier; Pirkko Vihko; Dino Moras
Functional and structural characterization of the insertion region in the ligand binding domain of the vitamin D nuclear receptor.
European journal of biochemistry / FEBS 2001;268(4):971-9.

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