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Ian Todd

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Jia Wang; Jonathan M Corne; Patrick J Tighe; Ian Todd; Richard Urbanowicz; Lucy C Fairclough
Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD).
Carolyn Tubby; Tim Harrison; Ian Todd; Lucy Fairclough
Immunological basis of reversible and fixed airways disease.
Prashantha M Vaitla; Paul M Radford; Patrick J Tighe; Richard J Powell; Elizabeth M McDermott; Ian Todd; Elizabeth Drewe
Role of interleukin-6 in a patient with tumor necrosis factor receptor-associated periodic syndrome: assessment of outcomes following treatment with the anti-interleukin-6 receptor monoclonal antibody tocilizumab.

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All Publications

2013: Jia Wang; Jonathan M Corne; Patrick J Tighe; Ian Todd; Richard Urbanowicz; Lucy C Fairclough
Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD).
PloS one 2013;8(3):e58556.
2011: Carolyn Tubby; Tim Harrison; Ian Todd; Lucy Fairclough
Immunological basis of reversible and fixed airways disease.
Clinical science (London, England : 1979) 2011;121(7):285-96.
2011: Prashantha M Vaitla; Paul M Radford; Patrick J Tighe; Richard J Powell; Elizabeth M McDermott; Ian Todd; Elizabeth Drewe
Role of interleukin-6 in a patient with tumor necrosis factor receptor-associated periodic syndrome: assessment of outcomes following treatment with the anti-interleukin-6 receptor monoclonal antibody tocilizumab.
Arthritis and rheumatism 2011;63(4):1151-5.
2010: Richard Urbanowicz; Jonathan R Lamb; Ian Todd; Jonathan M Corne; Lucy C Fairclough
Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients.
Respiratory research 2010;11():76.
2009: Richard Urbanowicz; Jonathan R Lamb; Ian Todd; Jonathan M Corne; Lucy C Fairclough
Altered effector function of peripheral cytotoxic cells in COPD.
Respiratory research 2009;10():53.
2009: Susana L Rebelo; Mohammad R Amel Kashipaz; Paul M Radford; Susan E Bainbridge; Roel Fiets; Johnny Fang; Elizabeth M McDermott; Richard J Powell; Ian Todd; Patrick J Tighe
Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line.
Arthritis and rheumatism 2009;60(1):269-80.
2008: Ian Todd; Patrick J Tighe; Susana Rebelo; Richard Powell
Cell surface expression of TNFRI in tumor necrosis factor receptor-associated periodic syndrome: comment on the article by Nedjai et al.
Arthritis and rheumatism 2008;58(7):2213-4; author reply 2214-5.
2007: Ian Todd; Paul M Radford; Loems Ziegler-Heitbrock; Amir M Ghaemmaghami; Richard J Powell; Patrick J Tighe
Elevated CD16 expression by monocytes from patients with tumor necrosis factor receptor-associated periodic syndrome.
Arthritis and rheumatism 2007;56(12):4182-8.
2007: Ian Todd; Paul M Radford; Noura Daffa; Susan E Bainbridge; Richard J Powell; Patrick J Tighe
Mutant tumor necrosis factor receptor associated with tumor necrosis factor receptor-associated periodic syndrome is altered antigenically and is retained within patients' leukocytes.
Arthritis and rheumatism 2007;56(8):2765-73.
2006: Susana L Rebelo; Susan E Bainbridge; Mohammad R Amel Kashipaz; Paul M Radford; Richard J Powell; Ian Todd; Patrick J Tighe
Modeling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function.
Arthritis and rheumatism 2006;54(8):2674-87.
2006: M L Nowlan; E Drewe; H Bulsara; N Esposito; R Adrian Robins; Patrick J Tighe; Richard J Powell; Ian Todd
Systemic cytokine levels and the effects of etanercept in TNF receptor-associated periodic syndrome (TRAPS) involving a C33Y mutation in TNFRSF1A.
Rheumatology (Oxford, England) 2006;45(1):31-7.
2005: David I Pritchard; Ian Todd; A Brown; Barrie W Bycroft; Siri Ram Chhabra; Paul Williams; P Wood
Alleviation of insulitis and moderation of diabetes in NOD mice following treatment with a synthetic Pseudomonas aeruginosa signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone.
Acta diabetologica 2005;42(3):119-22.
2005: Ian Todd; Mary L Nowlan; Elizabeth Drewe; Patrick J Tighe; Richard J Powell
Heterogeneity of tumor necrosis factor receptor-associated periodic syndrome: comment on the article by Siebert et al.
Arthritis and rheumatism 2005;52(9):2952; author reply 2952-3.
2005: Karen Robinson; Karl G Wooldridge; Damien B Wells; Amal Hasan; Ian Todd; Adrian Robins; Richard James; Dlawer A A Ala'Aldeen
T-cell-stimulating protein A elicits immune responses during meningococcal carriage and human disease.
Infection and immunity 2005;73(8):4684-93.
2005: L H Damanhouri; J A Dromey; M R Christie; Hassan A Nasrat; Mohammed Salleh M Ardawi; R Adrian Robins; Ian Todd
Autoantibodies to GAD and IA-2 in Saudi Arabian diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(4):448-52.
2005: Mary L Huggins; Ian Todd; Richard J Powell
Reactivation of Epstein-Barr virus in patients with systemic lupus erythematosus.
Rheumatology international 2005;25(3):183-7.
2004: Ian Todd; Paul M Radford; Kelly-Ann Draper-Morgan; Richard S McIntosh; Susan E Bainbridge; Peter Dickinson; Lama Jamhawi; Marios Sansaridis; Mary L Huggins; Patrick J Tighe; Richard J Powell
Mutant forms of tumour necrosis factor receptor I that occur in TNF-receptor-associated periodic syndrome retain signalling functions but show abnormal behaviour.
Immunology 2004;113(1):65-79.
2004: Mary L Huggins; Paul M Radford; Richard S McIntosh; Susan E Bainbridge; Peter Dickinson; Kelly-Ann Draper-Morgan; Patrick J Tighe; Richard J Powell; Ian Todd
Shedding of mutant tumor necrosis factor receptor superfamily 1A associated with tumor necrosis factor receptor-associated periodic syndrome: differences between cell types.
Arthritis and rheumatism 2004;50(8):2651-9.
2004: J Clifford Murray; Yee M Heng; Peter Symonds; K Rice; Wynne Ward; Mary L Huggins; Ian Todd; R Adrian Robins
Endothelial monocyte-activating polypeptide-II (EMAP-II): a novel inducer of lymphocyte apoptosis.
Journal of leukocyte biology 2004;75(5):772-6.
2004: James A Dromey; Sarah M Weenink; Günther H Peters; Josef Endl; Patrick J Tighe; Ian Todd; Michael R Christie
Mapping of epitopes for autoantibodies to the type 1 diabetes autoantigen IA-2 by peptide phage display and molecular modeling: overlap of antibody and T cell determinants.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4084-90.
2004: J Clifford Murray; Peter Symonds; Wynne Ward; Mary L Huggins; Anna Tiga; Katherine Rice; Yee M Heng; Ian Todd; R Adrian Robins
Colorectal cancer cells induce lymphocyte apoptosis by an endothelial monocyte-activating polypeptide-II-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):274-81.
2003: Mohammad R Amel Kashipaz; D Swinden; Ian Todd; Richard J Powell
Normal production of inflammatory cytokines in chronic fatigue and fibromyalgia syndromes determined by intracellular cytokine staining in short-term cultured blood mononuclear cells.
Clinical and experimental immunology 2003;132(2):360-5.
2003: Mohammad R Amel Kashipaz; Mary L Huggins; P Lanyon; Adrian Robins; Richard J Powell; Ian Todd
Assessment of Be1 and Be2 cells in systemic lupus erythematosus indicates elevated interleukin-10 producing CD5+ B cells.
Lupus 2003;12(5):356-63.
2002: Mohammad R Amel Kashipaz; Mary L Huggins; Richard J Powell; Ian Todd
Human autologous mixed lymphocyte reaction as an in vitro model for autoreactivity to apoptotic antigens.
Immunology 2002;107(3):358-65.
2002: T A M A Al-bukhari; Paul M Radford; G Bouras; C Davenport; SM Trigwell; G-F Bottazzo; M Lai; H L Schwartz; Patrick J Tighe; Ian Todd
Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): implications for autoantigen modification during pathogenesis.
Clinical and experimental immunology 2002;130(1):131-9.
2002: T A M A Al-bukhari; Patrick J Tighe; Ian Todd
An immuno-precipitation assay for determining specific interactions between antibodies and phage selected from random peptide expression libraries.
Journal of immunological methods 2002;264(1-2):163-71.
2002: Karen Robinson; Keith R Neal; C Howard; J Stockton; K Atkinson; E Scarth; J Moran; Adrian Robins; Ian Todd; EB Kaczmarski; S Gray; I Muscat; R Slack; Dlawer A A Ala'Aldeen
Characterization of humoral and cellular immune responses elicited by meningococcal carriage.
Infection and immunity 2002;70(3):1301-9.
2001: Ian Todd; Richard H Clothier; Mary L Huggins; N Patel; K C Searle; S Jeyarajah; L Pradel; K L Lacey
Electrical stimulation of transforming growth factor-beta 1 secretion by human dermal fibroblasts and the U937 human monocytic cell line.
Alternatives to laboratory animals : ATLA 2001;29(6):693-701.
2001: SM Trigwell; Paul M Radford; S R Page; AC Loweth; RF James; Noel G Morgan; Ian Todd
Islet glutamic acid decarboxylase modified by reactive oxygen species is recognized by antibodies from patients with type 1 diabetes mellitus.
Clinical and experimental immunology 2001;126(2):242-9.
2001: Mohammad R Amel Kashipaz; Mary L Huggins; P Lanyon; Adrian Robins; Ian Todd; Richard J Powell
Quantitative and qualitative analysis of the balance between type 1 and type 2 cytokine-producing CD8(-) and CD8(+) T cells in systemic lupus erythematosus.
Journal of autoimmunity 2001;17(2):155-63.
2001: Mary L Huggins; Ian Todd; Richard J Powell
CD40 ligand--an important target for immunotherapy?
Lupus 2001;10(1):1-3.
2000: K Ait-Tahar; Karl G Wooldridge; David P J Turner; M Atta; Ian Todd; Dlawer A A Ala'Aldeen
Auto-transporter A protein of Neisseria meningitidis: a potent CD4+ T-cell and B-cell stimulating antigen detected by expression cloning.
Molecular microbiology 2000;37(5):1094-105.
1999: Mary L Huggins; Ian Todd; M A Cavers; S R Pavuluri; Patrick J Tighe; Richard J Powell
Antibodies from systemic lupus erythematosus (SLE) sera define differential release of autoantigens from cell lines undergoing apoptosis.
Clinical and experimental immunology 1999;118(2):322-8.
1999: G Kizil; Ian Todd; M Atta; S Peter Borriello; K Ait-Tahar; Dlawer A A Ala'Aldeen
Identification and characterization of TspA, a major CD4(+) T-cell- and B-cell-stimulating Neisseria-specific antigen.
Infection and immunity 1999;67(7):3533-41.
1998: C Davenport; Paul M Radford; T A M A Al-bukhari; M Lai; G F Bottazzo; Ian Todd
Heterogeneity in the occurrence of a subset of autoantibodies to glutamic acid decarboxylase in autoimmune polyendocrine patients with islet cell antibodies.
Clinical and experimental immunology 1998;111(3):497-505.
1998: Ian Todd; JE McElveen; GE Lamming
Ovine trophoblast interferon enhances MHC class I expression by sheep endometrial cells.
Journal of reproductive immunology 1998;37(2):117-23.
1998: Ian Todd; C Davenport; J H Topping; P J Wood
IgG2a antibodies non-specifically delay the onset of diabetes in NOD mice.
Autoimmunity 1998;27(4):209-11.
1997: Angela Vincent; L M Grimaldi; G Martino; C Davenport; Ian Todd
Antibodies to 125I-glutamic acid decarboxylase in patients with stiff man syndrome.
Journal of neurology, neurosurgery, and psychiatry 1997;62(4):395-7.
1997: A C Wood; J S Chadwick; R S Brehm; Ian Todd; J P Arbuthnott; H S Tranter
Identification of antigenic sites on staphylococcal enterotoxin B and toxoid.
FEMS immunology and medical microbiology 1997;17(1):1-10.
1995: C Davenport; R Foxon; Ian Todd; G Lennox
Absence of glutamic acid decarboxylase autoimmunity in symptomatic palatal tremor.
Annals of neurology 1995;38(2):274-5.
1995: C Davenport; H Lovell; R F James; Ian Todd
Brain-reactive autoantibodies in BB/d rats do not recognize glutamic acid decarboxylase.
Clinical and experimental immunology 1995;101(1):127-35.
1995: M S Atta; W L Irving; R J Powell; Ian Todd
Enhanced expression of MHC class I molecules on cultured human thyroid follicular cells infected with reovirus through induction of type 1 interferons.
Clinical and experimental immunology 1995;101(1):121-6.
1995: A C Wood; Ian Todd
Staphylococcal enterotoxin B toxicity in BALB/c mice: effect on T-cells, plasma cytokine levels and biochemical markers.
FEMS immunology and medical microbiology 1995;11(2):91-7.
1995: M S Atta; K L Lim; D A Ala'deen; R J Powell; Ian Todd
Investigation of the prevalence and clinical associations of antibodies to human fibronectin in systemic lupus erythematosus.
Annals of the rheumatic diseases 1995;54(2):117-24.
1994: M S Atta; R J Powell; Ian Todd
The influence of anti-fibronectin antibodies on interactions involving extracellular matrix components and cells: a possible pathogenic mechanism.
Clinical and experimental immunology 1994;96(1):26-30.
1994: M S Atta; R J Powell; N D Hopkinson; Ian Todd
Human anti-fibronectin antibodies in systemic lupus erythematosus: occurrence and antigenic specificity.
Clinical and experimental immunology 1994;96(1):20-5.
1993: M R Holbrook; K E Young; L G Gibbon; CA Webster; H S Tranter; J P Arbuthnott; Ian Todd
Stimulation of rat spleen cells by staphylococcal enterotoxins.
FEMS immunology and medical microbiology 1993;7(2):169-74.
1992: C Davenport; G F Bottazzo; Ian Todd
Stimulation of human B cells specific for Candida albicans for monoclonal antibody production.
FEMS microbiology immunology 1992;4(6):335-43.
1991: A C Wood; Ian Todd; Alan Cockayne; J P Arbuthnott
Staphylococcal enterotoxins and the immune system.
FEMS microbiology immunology 1991;3(3):121-33.