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George Tofaris

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TOP 3
George K Tofaris
Lysosome-dependent pathways as a unifying theme in Parkinson's disease.
George K Tofaris; Ian W S Baker; Zameel M Cader; Binith J Cheeran; Sarosh R Irani; Angela Vincent
Immunotherapy-responsive chorea as the presenting feature of LGI1-antibody encephalitis.
George K Tofaris; Raphael Hourez; Jin-Woo Jung; Hyoung Tae Kim; kwang pyo kim; Alfred L Goldberg
Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway.

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All Publications

2012: George K Tofaris
Lysosome-dependent pathways as a unifying theme in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(11):1364-9.
2012: George K Tofaris; Ian W S Baker; Zameel M Cader; Binith J Cheeran; Sarosh R Irani; Angela Vincent
Immunotherapy-responsive chorea as the presenting feature of LGI1-antibody encephalitis.
Neurology 2012;79(2):195-6.
2011: George K Tofaris; Raphael Hourez; Jin-Woo Jung; Hyoung Tae Kim; kwang pyo kim; Alfred L Goldberg
Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(41):17004-9.
2010: Pablo Garcia-Reitböck; Oleg Anichtchik; Arianna Bellucci; Mariangela Iovino; Chiara Ballini; Elena Fineberg; Bernardino Ghetti; Laura Della Corte; PierFranco Spano; George K Tofaris; Michel Goedert; Maria Grazia Spillantini
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease.
Brain : a journal of neurology 2010;133(Pt 7):2032-44.
2007: George K Tofaris; Maria Grazia Spillantini
Physiological and pathological properties of alpha-synuclein.
Cellular and molecular life sciences : CMLS 2007;64(17):2194-201.
2007: George K Tofaris; Tamas Revesz; Thomas S Jacques; Savvas S Papacostas; Jeremy Chataway
Adult-onset neurodegeneration with brain iron accumulation and cortical alpha-synuclein and tau pathology: a distinct clinicopathological entity.
Archives of neurology 2007;64(2):280-2.
2007: Andrew W Michell; George K Tofaris; H Gossage; Pam Tyers; Maria Grazia Spillantini; Roger A Barker
The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease.
Cell transplantation 2007;16(5):461-74.
2006: George K Tofaris; Pablo Garcia Reitböck; Trevor Humby; Sarah L Lambourne; Mark O'Connell; Bernardino Ghetti; Helen Gossage; Piers C Emson; Lawrence S Wilkinson; Michel Goedert; Maria Grazia Spillantini
Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(15):3942-50.
2006: George K Tofaris; Trevor Wistow
An unusual cause of rigors and microscopic haematuria.
Lancet 2006;367(9510):622.
2005: George K Tofaris; Maria Grazia Spillantini
Alpha-synuclein dysfunction in Lewy body diseases.
Movement disorders : official journal of the Movement Disorder Society 2005;20 Suppl 12():S37-44.
2003: George K Tofaris; Azam Razzaq; Bernardino Ghetti; Kathryn S Lilley; Maria Grazia Spillantini
Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function.
The Journal of biological chemistry 2003;278(45):44405-11.
2002: George K Tofaris; Paul H Patterson; Kristjan R Jessen; Rhona Mirsky
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(15):6696-703.
2001: George K Tofaris; Robert Layfield; Maria Grazia Spillantini
alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome.
FEBS letters 2001;509(1):22-6.