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Ban-Hock Toh

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Immune Tolerance

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Tin Kyaw; Edgar Liu; Antonius G Rolink; Christopher Tay; Peter Tipping; Alex Bobik; Peng Cui; Hamid Hosseini; Peter Kanellakis; Ban-Hock Toh
BAFF receptor mAb treatment ameliorates development and progression of atherosclerosis in hyperlipidemic ApoE(-/-) mice.
Ban-Hock Toh; Roberta Taylor; T Kyaw; Wendy Pollock; Wolfgang Schlumberger
Parietal cell antibody identified by ELISA is superior to immunofluorescence, rises with age and is associated with intrinsic factor antibody.
H Hosseini; Zeyad Nasa; D Y Oh; Ban-Hock Toh; Hideo Yagita; Frank Alderuccio; S T Chan; X T Chen; J Chan
Non-myeloablative transplantation of bone marrow expressing self-antigen establishes peripheral tolerance and completely prevents autoimmunity in mice.

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2013: Tin Kyaw; Edgar Liu; Antonius G Rolink; Christopher Tay; Peter Tipping; Alex Bobik; Peng Cui; Hamid Hosseini; Peter Kanellakis; Ban-Hock Toh
BAFF receptor mAb treatment ameliorates development and progression of atherosclerosis in hyperlipidemic ApoE(-/-) mice.
PloS one 2013;8(4):e60430.
2012: Ban-Hock Toh; Roberta Taylor; T Kyaw; Wendy Pollock; Wolfgang Schlumberger
Parietal cell antibody identified by ELISA is superior to immunofluorescence, rises with age and is associated with intrinsic factor antibody.
Autoimmunity 2012;45(7):527-32.
2012: H Hosseini; Zeyad Nasa; D Y Oh; Ban-Hock Toh; Hideo Yagita; Frank Alderuccio; S T Chan; X T Chen; J Chan
Non-myeloablative transplantation of bone marrow expressing self-antigen establishes peripheral tolerance and completely prevents autoimmunity in mice.
Gene therapy 2012;19(11):1075-84.
2012: Zeyad Nasa; Ban-Hock Toh; J Chan; J-Y Chung; Frank Alderuccio
Nonmyeloablative conditioning generates autoantigen-encoding bone marrow that prevents and cures an experimental autoimmune disease.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012;12(8):2062-71.
2012: Frank Alderuccio; Ban-Hock Toh
Tackling autoimmunity with gene therapy.
Chimerism 2012;3(3):1-4.
2012: Christopher Siatskas; Aude Silvain; Guizhi Sun; Ban-Hock Toh; Frank Alderuccio; B Thomas Bäckström; Richard L Boyd; Ashley Emerson-Webber; Natalie Seach; Claude C Bernard
Thymic gene transfer of myelin oligodendrocyte glycoprotein ameliorates the onset but not the progression of autoimmune demyelination.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(7):1349-59.
2012: Ban-Hock Toh; James Chan; Tin Kyaw; Frank Alderuccio
Cutting edge issues in autoimmune gastritis.
Clinical reviews in allergy & immunology 2012;42(3):269-78.
2012: Ding Yuan Oh; Ban-Hock Toh; Peng Cui; Hamid Hosseini; Jennifer Mosse; James Chan
Potently immunosuppressive 5-fluorouracil-resistant mesenchymal stromal cells completely remit an experimental autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(5):2207-17.
2012: Tin Kyaw; Peter Tipping; Alex Bobik; Ban-Hock Toh
Protective role of natural IgM-producing B1a cells in atherosclerosis.
Trends in cardiovascular medicine 2012;22(2):48-53.
2012: Yu Han Liu; Ursula Manuelpillai; Ding Yuan Oh; Jing Yang Tee; Kelly To; Ban-Hock Toh; Vijesh Vaghjiani; Peng Cui; James Chan
Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis.
PloS one 2012;7(4):e35758.
2011: Frank Alderuccio; James Chan; Jieyu Chung; Hyun-Ja Ko; Zeyad Nasa; Ban-Hock Toh
Hematopoietic stem cell gene therapy as a treatment for autoimmune diseases.
Molecular pharmaceutics 2011;8(5):1488-94.
2011: Xiang T Chen; Hamid Hosseini; Daniel Layton; Ban-Hock Toh; Frank Alderuccio; Richard Boyd; Siow T Chan; James Chan
Transplantation of retrovirally transduced bone marrow prevents autoimmune disease in aged mice by peripheral tolerance mechanisms.
Autoimmunity 2011;44(5):384-93.
2011: Hyun-Ja Ko; Jie-Yu Chung; Zeyad Nasa; James Chan; Christopher Siatskas; Ban-Hock Toh; Frank Alderuccio
Targeting MOG expression to dendritic cells delays onset of experimental autoimmune disease.
Autoimmunity 2011;44(3):177-87.
2011: James Chan; Frank Alderuccio; Ban-Hock Toh
Transplantation of genetically modified haematopoietic stem cells to induce antigen-specific tolerance as a cure for autoimmune diseases.
Current stem cell research & therapy 2011;6(1):44-9.
2010: Hyun-Ja Ko; Sarah A Kinkel; FX Hubert; Zeyad Nasa; James Chan; Christopher Siatskas; Premila Hirubalan; Ban-Hock Toh; Hamish Scott; Frank Alderuccio
Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis.
European journal of immunology 2010;40(12):3499-509.
2010: Frank Alderuccio; James Chan; Hyun-Ja Ko; Jie-Yu Chung; Zeyad Nasa; Ban-Hock Toh
A molecular Trojan horse: hijacking the bone marrow to treat autoimmune diseases.
Discovery medicine 2010;9(49):512-8.
2010: Ban-Hock Toh; Roberta Taylor; Wendy Pollock; Sharon Dearden; Cassandra C Gill; Carol Buchner; Rufus W Burlingame
'Actin-reactive' discriminated from 'non-actin-reactive' smooth muscle autoantibody by immunofluorescence reactivity with rat epithelial cell line.
Pathology 2010;42(5):463-9.
2009: Frank Alderuccio; James Chan; David W Scott; Ban-Hock Toh
Gene therapy and bone marrow stem-cell transfer to treat autoimmune disease.
Trends in molecular medicine 2009;15(8):344-51.
2008: James Chan; Ee Jun Ban; Keng Hao Chun; Shunhe Wang; B Thomas Bäckström; Claude C A Bernard; Ban-Hock Toh; Frank Alderuccio
Transplantation of bone marrow transduced to express self-antigen establishes deletional tolerance and permanently remits autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(11):7571-80.
2008: Frank Alderuccio; James Chan; Ban-Hock Toh
Tweaking the immune system: gene therapy-assisted autologous haematopoietic stem cell transplantation as a treatment for autoimmune disease.
Autoimmunity 2008;41(8):679-85.
2008: Judith Field; Frank Alderuccio; Paul Hertzog; Ban-Hock Toh
GM-CSF-induced autoimmune gastritis in interferon alpha receptor deficient mice.
Journal of autoimmunity 2008;31(3):274-80.
2008: James Chan; Ee Jun Ban; Keng Hao Chun; Shunhe Wang; Jonathan McQualter; Claude Bernard; Ban-Hock Toh; Frank Alderuccio
Methylprednisolone induces reversible clinical and pathological remission and loss of lymphocyte reactivity to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis.
Autoimmunity 2008;41(5):405-13.
2006: James Chan; Warren Clements; Judith Field; Zeyad Nasa; Peter Lock; Felicia Yap; Ban-Hock Toh; Frank Alderuccio
Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice.
The journal of gene medicine 2006;8(11):1281-90.
2006: Michael Ditiatkovski; Ban-Hock Toh; Alex Bobik
GM-CSF deficiency reduces macrophage PPAR-gamma expression and aggravates atherosclerosis in ApoE-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2337-44.
2006: Frank Alderuccio; Christopher Siatskas; James Chan; Judith Field; Kim Murphy; Zeyad Nasa; Ban-Hock Toh
Haematopoietic stem cell gene therapy to treat autoimmune disease.
Current stem cell research & therapy 2006;1(3):279-87.
2006: Mark Biondo; Judith Field; Ban-Hock Toh; Frank Alderuccio
Prednisolone promotes remission and gastric mucosal regeneration in experimental autoimmune gastritis.
The Journal of pathology 2006;209(3):384-91.
2006: Christopher Siatskas; James Chan; Judith Field; Kim Murphy; Zeyad Nasa; Ban-Hock Toh; Frank Alderuccio
Gene therapy strategies towards immune tolerance to treat the autoimmune diseases.
Current gene therapy 2006;6(1):45-58.
2006: He Li; Dakang Xu; Ban-Hock Toh; Jun-Ping Liu
TGF-beta and cancer: is Smad3 a repressor of hTERT gene?
Cell research 2006;16(2):169-73.
2005: He Li; Alexander Ruvantha Pinto; Wenzhou Duan; Jinhua Li; Ban-Hock Toh; Jun-Ping Liu
Telomerase down-regulation does not mediate PC12 pheochromocytoma cell differentiation induced by NGF, but requires MAP kinase signalling.
Journal of neurochemistry 2005;95(3):891-901.
2005: Frank Alderuccio; Kim Murphy; Mark Biondo; Judith Field; Ban-Hock Toh
Reversing the autoimmune condition: experience with experimental autoimmune gastritis.
International reviews of immunology 2005;24(1-2):135-55.
2005: Aiden C J Marshall; Frank Alderuccio; Kim Murphy; Ban-Hock Toh
Mechanisms of gastric mucosal cell loss in autoimmune gastritis.
International reviews of immunology 2005;24(1-2):123-34.
2005: Judith Field; Mark Biondo; Kim Murphy; Frank Alderuccio; Ban-Hock Toh
Experimental autoimmune gastritis: mouse models of human organ-specific autoimmune disease.
International reviews of immunology 2005;24(1-2):93-110.
2004: Frank Alderuccio; Ban-Hock Toh
Induction of tolerance to self-antigens using genetically modified bone marrow cells.
Expert opinion on biological therapy 2004;4(7):1007-14.
2004: Ban-Hock Toh; Frank Alderuccio
Pernicious anaemia.
Autoimmunity 2004;37(4):357-61.
2004: Aiden C J Marshall; Ban-Hock Toh; Frank Alderuccio
Tumor necrosis factor alpha is not implicated in the genesis of experimental autoimmune gastritis.
Journal of autoimmunity 2004;22(1):1-11.
2003: Judith Field; Aiden C J Marshall; Paul J Hertzog; Timothy Wells; Frank Alderuccio; Ban-Hock Toh
Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis.
Clinical immunology (Orlando, Fla.) 2003;109(2):238-47.
2003: Frank Alderuccio; Kim Murphy; Ban-Hock Toh
Stem cells engineered to express self-antigen to treat autoimmunity.
Trends in immunology 2003;24(4):176-80.
2003: Kim Murphy; Mark Biondo; Ban-Hock Toh; Frank Alderuccio
Tolerance established in autoimmune disease by mating or bone marrow transplantation that target autoantigen to thymus.
International immunology 2003;15(2):269-77.
2002: Aiden C J Marshall; Frank Alderuccio; Ban-Hock Toh
Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis.
Gastroenterology 2002;123(3):780-9.
2002: Deanne L V Greenwood; Veronika M Gitlits; Frank Alderuccio; John W Sentry; Ban-Hock Toh
Autoantibodies in neuropsychiatric lupus.
Autoimmunity 2002;35(2):79-86.
2002: Kate Dunster; Ban-Hock Toh; John W Sentry
Early endosomes, late endosomes, and lysosomes display distinct partitioning strategies of inheritance with similarities to Golgi-derived membranes.
European journal of cell biology 2002;81(3):117-24.
2002: Frank Alderuccio; Mark Biondo; Ban-Hock Toh
Organ-specific autoimmunity in granulocyte macrophage-colony stimulating factor (GM-CSF) deficient mice.
Autoimmunity 2002;35(1):67-73.
2002: Frank Alderuccio; John W Sentry; Aiden C J Marshall; Mark Biondo; Ban-Hock Toh
Animal models of human disease: experimental autoimmune gastritis--a model for autoimmune gastritis and pernicious anemia.
Clinical immunology (Orlando, Fla.) 2002;102(1):48-58.
2001: Katrina L Scarff; Louise M Judd; Wendy E Wilson; Karen L Laurie; Ban-Hock Toh; Paul A Gleeson; Ian R van Driel
Requirements for autoimmune responses to mouse gastric autoantigens.
Immunology 2001;104(4):392-401.
2001: Z Chai; Boris Sarcevic; Amanda Mawson; Ban-Hock Toh
SET-related cell division autoantigen-1 (CDA1) arrests cell growth.
The Journal of biological chemistry 2001;276(36):33665-74.
2001: Veronika M Gitlits; John W Sentry; L S Matthew; A Ian Smith; Ban-Hock Toh
Synapsin I identified as a novel brain-specific autoantigen.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(3):276-83.
2001: F P L Lai; Y Tsukada; H Ichikawa; Kate Dunster; John W Sentry; Ban-Hock Toh
Autoantibody to DNA excision repair enzyme hMYH in a patient with rheumatic disease.
Clinical immunology (Orlando, Fla.) 2001;99(2):291-7.
2001: Veronika M Gitlits; Ban-Hock Toh; John W Sentry
Disease association, origin, and clinical relevance of autoantibodies to the glycolytic enzyme enolase.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(2):138-45.
2001: Z Yang; He Li; Z Chai; Meryl J Fullerton; Y Cao; Ban-Hock Toh; John W Funder; Jun-Ping Liu
Dynamin II regulates hormone secretion in neuroendocrine cells.
The Journal of biological chemistry 2001;276(6):4251-60.
2001: Mark Biondo; Zeyad Nasa; A Marshall; Ban-Hock Toh; Frank Alderuccio
Local transgenic expression of granulocyte macrophage-colony stimulating factor initiates autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):2090-9.
2001: Deanne L V Greenwood; John W Sentry; Ban-Hock Toh
Characterisation of proton pump antibodies and stomach pathology in gastritis induced by neonatal immunisation without adjuvant.
Autoimmunity 2001;34(2):81-94.
2001: Nicole L La Gruta; Ian R van Driel; Ban-Hock Toh; Paul A Gleeson
The role of natural killer cells in the induction of autoimmune gastritis.
Autoimmunity 2001;34(2):147-54.
2000: Yoshito Tsukada; H Ichikawa; Z Chai; F P L Lai; Kate Dunster; John W Sentry; Ban-Hock Toh
Novel variant of p230 trans-Golgi network protein identified by serum from Sjögren's syndrome patient.
European journal of cell biology 2000;79(11):790-4.
2000: Frank Alderuccio; Ban-Hock Toh
Immunopathology of autoimmune gastritis: lessons from mouse models.
Histology and histopathology 2000;15(3):869-79.
2000: Ban-Hock Toh; John W Sentry; Frank Alderuccio
The causative H+/K+ ATPase antigen in the pathogenesis of autoimmune gastritis.
Immunology today 2000;21(7):348-54.
2000: Veronika M Gitlits; S L Macaulay; Ban-Hock Toh; John W Sentry
Novel human autoantibodies to phosphoepitopes on mitotic chromosomal autoantigens (MCAs).
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2000;48(3):172-82.
2000: Frank Alderuccio; V Cataldo; Ian R van Driel; Paul A Gleeson; Ban-Hock Toh
Tolerance and autoimmunity to a gastritogenic peptide in TCR transgenic mice.
International immunology 2000;12(3):343-52.
2000: Veronika M Gitlits; Ban-Hock Toh; K L Loveland; John W Sentry
The glycolytic enzyme enolase is present in sperm tail and displays nucleotide-dependent association with microtubules.
European journal of cell biology 2000;79(2):104-11.
2000: Simon P Barrett; A Riordon; Ban-Hock Toh; Paul A Gleeson; Ian R van Driel
Homing and adhesion molecules in autoimmune gastritis.
Journal of leukocyte biology 2000;67(2):169-73.
2000: Harini D de Silva; Frank Alderuccio; Ban-Hock Toh; Ian R van Driel; P A Gleeso
Defining T cell receptors which recognise the immunodominant epitope of the gastric autoantigen, the H/K ATPase beta-subunit.
Autoimmunity 2000;33(1):1-14.
1999: W Pollock; Ban-Hock Toh
Routine immunofluorescence detection of Ro/SS-A autoantibody using HEp-2 cells transfected with human 60 kDa Ro/SS-A.
Journal of clinical pathology 1999;52(9):684-7.
1999: Katrina L Scarff; Louise M Judd; Ban-Hock Toh; Paul A Gleeson; Ian R van Driel
Gastric H(+),K(+)-adenosine triphosphatase beta subunit is required for normal function, development, and membrane structure of mouse parietal cells.
Gastroenterology 1999;117(3):605-18.
1999: Louise M Judd; Paul A Gleeson; Ban-Hock Toh; Ian R van Driel
Autoimmune gastritis results in disruption of gastric epithelial cell development.
The American journal of physiology 1999;277(1 Pt 1):G209-18.
1999: L A Stewart; Ian R van Driel; Ban-Hock Toh; Paul A Gleeson
Species-specific distribution of alpha-galactosyl epitopes on the gastric H/K ATPase beta-subunit: relevance to the binding of human anti-parietal cell autoantibodies.
Glycobiology 1999;9(6):601-6.
1999: Harini D de Silva; Paul A Gleeson; Ban-Hock Toh; Ian R van Driel; F R Carbone
Identification of a gastritogenic epitope of the H/K ATPase beta-subunit.
Immunology 1999;96(1):145-51.
1998: Frank Alderuccio; Ban-Hock Toh
Spontaneous autoimmune gastritis in C3H/He mice: a new mouse model for gastric autoimmunity.
The American journal of pathology 1998;153(4):1311-8.
1998: Harini D de Silva; Ian R van Driel; Nicole L La Gruta; Ban-Hock Toh; Paul A Gleeson
CD4+ T cells, but not CD8+ T cells, are required for the development of experimental autoimmune gastritis.
Immunology 1998;93(3):405-8.
1998: R L Waite; John W Sentry; H Stenmark; Ban-Hock Toh
Autoantibodies to a novel early endosome antigen 1.
Clinical immunology and immunopathology 1998;86(1):81-7.
1997: Ban-Hock Toh; Ian R van Driel; Paul A Gleeson
Pernicious anemia.
The New England journal of medicine 1997;337(20):1441-8.
1997: Veronika M Gitlits; John W Sentry; M L Matthew; A Ian Smith; Ban-Hock Toh
Autoantibodies to evolutionarily conserved epitopes of enolase in a patient with discoid lupus erythematosus.
Immunology 1997;92(3):362-8.
1997: K J Scarff; J M Pettitt; Ian R van Driel; Paul A Gleeson; Ban-Hock Toh
Immunization with gastric H+/K(+)-ATPase induces a reversible autoimmune gastritis.
Immunology 1997;92(1):91-8.
1997: Frank Alderuccio; Paul A Gleeson; Stuart P Berzins; M Martin; Ian R van Driel; Ban-Hock Toh
Expression of the gastric H/K-ATPase alpha-subunit in the thymus may explain the dominant role of the beta-subunit in the pathogenesis of autoimmune gastritis.
Autoimmunity 1997;25(3):167-75.
1996: Paul A Gleeson; T J Anderson; J L Stow; G Griffiths; Ban-Hock Toh; F Matheson
p230 is associated with vesicles budding from the trans-Golgi network.
Journal of cell science 1996;109 ( Pt 12)():2811-21.
1996: S P Barrett; Paul A Gleeson; H de Silva; Ban-Hock Toh; Ian R van Driel
Interferon-gamma is required during the initiation of an organ-specific autoimmune disease.
European journal of immunology 1996;26(7):1652-5.
1996: T M Martinelli; Ian R van Driel; Frank Alderuccio; Paul A Gleeson; Ban-Hock Toh
Analysis of mononuclear cell infiltrate and cytokine production in murine autoimmune gastritis.
Gastroenterology 1996;110(6):1791-802.
1996: R Erlich; Paul A Gleeson; P Campbell; E Dietzsch; Ban-Hock Toh
Molecular characterization of trans-Golgi p230. A human peripheral membrane protein encoded by a gene on chromosome 6p12-22 contains extensive coiled-coil alpha-helical domains and a granin motif.
The Journal of biological chemistry 1996;271(14):8328-37.
1996: J M Pettitt; Ian R van Driel; Ban-Hock Toh; Paul A Gleeson
From coiled tubules to a secretory canaliculus: a new model for membrane transformation and acid secretion by gastric parietal cells.
Trends in cell biology 1996;6(2):49-53.
1996: Paul A Gleeson; Ban-Hock Toh; Ian R van Driel
Organ-specific autoimmunity induced by lymphopenia.
Immunological reviews 1996;149():97-125.
1995: S P Barrett; Ian R van Driel; S S Tan; Frank Alderuccio; Ban-Hock Toh; Paul A Gleeson
Expression of a gastric autoantigen in pancreatic islets results in non-destructive insulitis after neonatal thymectomy.
European journal of immunology 1995;25(9):2686-94.
1995: F T Mu; judy callaghan; Olivia Steele-Mortimer; Harald Stenmark; Robert Parton; P L Campbell; J McCluskey; J P Yeo; E P Tock; Ban-Hock Toh
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif.
The Journal of biological chemistry 1995;270(22):13503-11.
1995: judy callaghan; S S Tan; M A Khan; K A Curran; W G Campbell; Adam J Smolka; Ban-Hock Toh; Paul A Gleeson; Charles S Wingo; Brian D Cain
Renal expression of the gene encoding the gastric H(+)-K(+)-ATPase beta-subunit.
The American journal of physiology 1995;268(3 Pt 2):F363-74.
1995: J M Pettitt; D C Humphris; S P Barrett; Ban-Hock Toh; Ian R van Driel; Paul A Gleeson
Fast freeze-fixation/freeze-substitution reveals the secretory membranes of the gastric parietal cell as a network of helically coiled tubule. A new model for parietal cell transformation.
Journal of cell science 1995;108 ( Pt 3)():1127-41.
1995: Frank Alderuccio; Ban-Hock Toh; Paul A Gleeson; Ian R van Driel
A novel method for isolating mononuclear cells from the stomachs of mice with experimental autoimmune gastritis.
Autoimmunity 1995;21(3):215-21.
1995: S P Barrett; Ban-Hock Toh; Frank Alderuccio; Ian R van Driel; Paul A Gleeson
Organ-specific autoimmunity induced by adult thymectomy and cyclophosphamide-induced lymphopenia.
European journal of immunology 1995;25(1):238-44.
1994: J P Yeo; A Forer; Ban-Hock Toh
A homologue of the human regulator of mitotic spindle assembly protein (RMSA-1) is present in crane fly and is associated with meiotic chromosomes.
Journal of cell science 1994;107 ( Pt 7)():1845-51.
1994: J Kooy; Ban-Hock Toh; Paul A Gleeson
Heterogeneity of human anti-Golgi auto-antibodies: reactivity with components from 35 to 260 kDa.
Immunology and cell biology 1994;72(2):123-7.
1994: J P Yeo; Frank Alderuccio; Ban-Hock Toh
A new chromosomal protein essential for mitotic spindle assembly.
Nature 1994;367(6460):288-91.
1994: J P Yeo; Ban-Hock Toh
Cell cycle-associated autoantibodies: markers for autoimmunity and probes for molecular cell biology.
Autoimmunity 1994;18(4):291-300.
1993: Frank Alderuccio; Ban-Hock Toh; S S Tan; Paul A Gleeson; Ian R van Driel
An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus.
The Journal of experimental medicine 1993;178(2):419-26.
1993: J M Pettitt; Ban-Hock Toh; judy callaghan; Paul A Gleeson; Ian R van Driel
Gastric parietal cell development: expression of the H+/K+ ATPase subunits coincides with the biogenesis of the secretory membranes.
Immunology and cell biology 1993;71 ( Pt 3)():191-200.
1993: judy callaghan; M A Khan; Frank Alderuccio; Ian R van Driel; Paul A Gleeson; Ban-Hock Toh
Alpha and beta subunits of the gastric H+/K(+)-ATPase are concordantly targeted by parietal cell autoantibodies associated with autoimmune gastritis.
Autoimmunity 1993;16(4):289-95.
1992: J Kooy; Ban-Hock Toh; J M Pettitt; R Erlich; Paul A Gleeson
Human autoantibodies as reagents to conserved Golgi components. Characterization of a peripheral, 230-kDa compartment-specific Golgi protein.
The Journal of biological chemistry 1992;267(28):20255-63.
1992: judy callaghan; Ban-Hock Toh; R J Simpson; G S Baldwin; Paul A Gleeson
Rapid purification of the gastric H+/K(+)-ATPase complex by tomato-lectin affinity chromatography.
The Biochemical journal 1992;283 ( Pt 1)():63-8.
1992: G P Morley; judy callaghan; J B Rose; Ban-Hock Toh; Paul A Gleeson; Ian R van Driel
The mouse gastric H,K-ATPase beta subunit. Gene structure and co-ordinate expression with the alpha subunit during ontogeny.
The Journal of biological chemistry 1992;267(2):1165-74.
1992: Ban-Hock Toh; Ian R van Driel; Paul A Gleeson
Autoimmune gastritis: tolerance and autoimmunity to the gastric H+/K+ ATPase (proton pump).
Autoimmunity 1992;13(2):165-72.
1992: J S Chuang; judy callaghan; Paul A Gleeson; Ban-Hock Toh
Diagnostic ELISA for parietal cell autoantibody using tomato lectin-purified gastric H+/K(+)-ATPase (proton pump).
Autoimmunity 1992;12(1):1-7.
1991: C M Jones; judy callaghan; Paul A Gleeson; Y Mori; T Masuda; Ban-Hock Toh
The parietal cell autoantigens recognized in neonatal thymectomy-induced murine gastritis are the alpha and beta subunits of the gastric proton pump [corrected].
Gastroenterology 1991;101(2):287-94.
1991: Paul A Gleeson; Ban-Hock Toh
Molecular targets in pernicious anaemia.
Immunology today 1991;12(7):233-8.
1991: I Goldkorn; Paul A Gleeson; Ban-Hock Toh
Reverse immunoaffinity chromatography: application to the purification of the 60- to 90-kDa gastric parietal cell autoantigen associated with autoimmune gastritis.
Analytical biochemistry 1991;194(2):433-8.
1991: C M Jones; Ban-Hock Toh; J M Pettitt; T M Martinelli; D C Humphris; judy callaghan; I Goldkorn; F T Mu; Paul A Gleeson
Monoclonal antibodies specific for the core protein of the beta-subunit of the gastric proton pump (H+/K+ ATPase). An autoantigen targetted in pernicious anaemia.
European journal of biochemistry / FEBS 1991;197(1):49-59.
1991: Ban-Hock Toh
Anti-cytoskeletal autoantibodies: diagnostic significance for liver diseases, infections and systemic autoimmune diseases.
Autoimmunity 1991;11(2):119-25.
1990: Ban-Hock Toh; Paul A Gleeson; R J Simpson; R L Moritz; judy callaghan; I Goldkorn; C M Jones; T M Martinelli; F T Mu; D C Humphris
The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a beta subunit of the gastric H+/K(+)-ATPase (proton pump).
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6418-22.
1990: E T Thean; Ban-Hock Toh
Serum human alpha-lactalbumin as a marker for breast cancer.
British journal of cancer 1990;61(5):773-5.
1990: judy callaghan; Ban-Hock Toh; J M Pettitt; D C Humphris; Paul A Gleeson
Poly-N-acetyllactosamine-specific tomato lectin interacts with gastric parietal cells. Identification of a tomato-lectin binding 60-90 X 10(3) Mr membrane glycoprotein of tubulovesicles.
Journal of cell science 1990;95 ( Pt 4)():563-76.
1989: I Goldkorn; Paul A Gleeson; Ban-Hock Toh
Gastric parietal cell antigens of 60-90, 92, and 100-120 kDa associated with autoimmune gastritis and pernicious anemia. Role of N-glycans in the structure and antigenicity of the 60-90-kDa component.
The Journal of biological chemistry 1989;264(31):18768-74.
1989: Frank Alderuccio; D Witherden; Ban-Hock Toh; A Barnett
Autoantibody to gp50, a glycoprotein shared in common between fibroblasts and lymphocytes, in progressive systemic sclerosis.
Clinical and experimental immunology 1989;78(1):26-30.
1989: E T Thean; Ban-Hock Toh
Western immunoblotting: temperature-dependent reduction in background staining.
Analytical biochemistry 1989;177(2):256-8.
1989: E T Thean; Ban-Hock Toh
Production and characterization of murine monoclonal antibody to human alpha-lactalbumin.
Immunology and cell biology 1989;67 ( Pt 1)():41-8.
1989: Frank Alderuccio; Jennifer M Rolland; G C Toner; M A Schwarz; James McCluskey; Ban-Hock Toh
Autoantibodies to neurons and to the cytoskeleton in small cell carcinoma with paraneoplastic sensory neuropathy.
Autoimmunity 1989;5(1-2):115-23.
1988: Ban-Hock Toh
Autoantibodies: the search for origins, target autoantigens and pathogenicity.
Annals of the Academy of Medicine, Singapore 1988;17(2):190-4.
1988: F T Mu; Frank Alderuccio; Ban-Hock Toh; M Eric Gershwin; Ross Coppel; I R Mackay
Murine monoclonal antibody to mitochondria reacts with the 72 kD antigen of primary biliary cirrhosis.
Clinical and experimental immunology 1988;71(1):100-6.
1987: C Brown; Ban-Hock Toh; J S Pedersen; F M Clarke; I R Mackay; I Gust
Autoantibody to aldolase in acute and chronic hepatitis.
Pathology 1987;19(4):347-50.
1986: Frank Alderuccio; Ban-Hock Toh; A J Barnett; J S Pedersen
Identification and characterization of mitochondria autoantigens in progressive systemic sclerosis: identity with the 72,000 dalton autoantigen in primary biliary cirrhosis.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(6):1855-9.
1986: Frank Alderuccio; A J Barnett; J H Campbell; J S Pedersen; Ban-Hock Toh
Scl-95/100: doublet of endothelial marker autoantigens in progressive systemic sclerosis.
Clinical and experimental immunology 1986;64(1):94-100.
1986: R A Strugnell; W F Williams; L Drummond; J S Pedersen; Ban-Hock Toh; S Faine
Development of increased serum immunoblot reactivity against a 45,000-dalton polypeptide of Treponema pallidum (Nichols) correlates with establishment of chancre immunity in syphilitic rabbits.
Infection and immunity 1986;51(3):957-60.
1986: R A Strugnell; W F Williams; G Raines; J S Pedersen; L P Drummond; Ban-Hock Toh; S Faine
Autoantibodies to creatine kinase in rabbits infected with Treponema pallidum.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(2):667-71.
1985: C A Dow; H J De Aizpurua; J S Pedersen; B Ungar; Ban-Hock Toh
65-70 kD protein identified by immunoblotting as the presumptive gastric microsomal autoantigen in pernicious anaemia.
Clinical and experimental immunology 1985;62(3):732-7.
1985: H J de Aizpurua; B Ungar; Ban-Hock Toh
Autoantibody to the gastrin receptor in pernicious anemia.
The New England journal of medicine 1985;313(8):479-83.
1985: H J de Aizpurua; B Ungar; Ban-Hock Toh
Serum from patients with pernicious anaemia blocks gastrin stimulation of acid secretion by parietal cells.
Clinical and experimental immunology 1985;61(2):315-22.
1985: J R Underwood; J S Pedersen; P J Chalmers; Ban-Hock Toh
Hybrids from normal, germ free, nude and neonatal mice produce monoclonal autoantibodies to eight different intracellular structures.
Clinical and experimental immunology 1985;60(2):417-26.
1985: A L Cunningham; I R Mackay; I H Frazer; C Brown; J S Pedersen; Ban-Hock Toh; Brian Tait; F M Clarke
Antibody to G-actin in different categories of alcoholic liver disease: quantification by an ELISA and significance for alcoholic cirrhosis.
Clinical immunology and immunopathology 1985;34(2):158-64.
1984: J S Pedersen; J R Underwood; Ban-Hock Toh
Vimentin organizing centre in cultured epithelial cells.
Pathology 1984;16(4):393-5.
1984: S J Lolait; J R Underwood; F T Mu; Frank Alderuccio; C A Dow; J S Pedersen; P J Chalmers; Ban-Hock Toh
Vimentin intermediate filaments in cultures of human meningiomas.
Neuropathology and applied neurobiology 1984;10(5):321-31.
1983: H J De Aizpurua; B Ungar; Ban-Hock Toh
Flow microfluorimetric analysis of autoantibody reactions with parietal cell surface membranes in pernicious anaemia.
Clinical and experimental immunology 1983;54(2):405-10.
1983: S J Lolait; J H Harmer; G Auteri; J S Pedersen; Ban-Hock Toh
Expression of glial fibrillary acidic protein, actin, fibronectin and factor VIII antigen in human astrocytomas.
Pathology 1983;15(4):373-8.
1983: H J De Aizpurua; L J Cosgrove; B Ungar; Ban-Hock Toh
Autoantibodies cytotoxic to gastric parietal cells in serum of patients with pernicious anemia.
The New England journal of medicine 1983;309(11):625-9.
1983: S J Lolait; J H Harmer; D Dahl; Ban-Hock Toh
Growth and gliotic response of astrocytes in vitro.
The Australian journal of experimental biology and medical science 1983;61 (Pt 4)():439-49.
1983: J H Harmer; S J Lolait; Ban-Hock Toh; J S Pedersen; C Chaponnier; G Gabbiani
Actin depolymerizing factor and the organization and distribution of actin in astrocytomas and meningiomas.
British journal of cancer 1983;48(1):89-93.
1983: R A Strugnell; J R Underwood; F M Clarke; J S Pedersen; P J Chalmers; S Faine; Ban-Hock Toh
A monoclonal IgM smooth muscle antibody reactive with fibroblast stress fibres produced by immunization with Treponema pallidum.
Clinical and experimental immunology 1983;52(3):537-42.
1983: H J de Aizpurua; Ban-Hock Toh; B Ungar
Parietal cell surface reactive autoantibody in pernicious anaemia demonstrated by indirect membrane immunofluorescence.
Clinical and experimental immunology 1983;52(2):341-9.
1983: L Bretherton; C Brown; J S Pedersen; Ban-Hock Toh; F M Clarke; I R Mackay; I D Gust
ELISA assay for IgG autoantibody to G-actin: comparison of chronic active hepatitis and acute viral hepatitis.
Clinical and experimental immunology 1983;51(3):611-6.