FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Chihiro Tohda

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Disorders

Procedures

Immunohistochemistry

Co-author Network

Publications

TOP 3
Kiyoshi Teshigawara; Tomoharu Kuboyama; Yuji Matsuya; Aiko Nagata; Michiko Shigyo; Kenji Sugimoto; Chihiro Tohda
A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentin.
Chihiro Tohda; Aiko Nagata
Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury.
Chihiro Tohda; Masahito Umezaki; Takuya Urano; Ilka Nemere; Tomoharu Kuboyama
Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Chihiro Tohda (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Kiyoshi Teshigawara; Tomoharu Kuboyama; Yuji Matsuya; Aiko Nagata; Michiko Shigyo; Kenji Sugimoto; Chihiro Tohda
A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentin.
British journal of pharmacology 2013;168(4):903-19.
2012: Chihiro Tohda; Aiko Nagata
Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury.
Evidence-based complementary and alternative medicine : eCAM 2012;2012():731208.
2012: Chihiro Tohda; Masahito Umezaki; Takuya Urano; Ilka Nemere; Tomoharu Kuboyama
Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice.
Scientific reports 2012;2():535.
2011: Chihiro Tohda; Takuya Urano; Rie Nakada; Akira Okonogi; Tomoharu Kuboyama
Kamikihi-to (KKT) rescues axonal and synaptic degeneration associated with memory impairment in a mouse model of Alzheimer's disease, 5XFAD.
The International journal of neuroscience 2011;121(12):641-8.
2011: Chihiro Tohda; Tomoharu Kuboyama
Current and future therapeutic strategies for functional repair of spinal cord injury.
Pharmacology & therapeutics 2011;132(1):57-71.
2011: Yanjing Bai; Masao Hattori; Chihiro Tohda; Shu Zhu; Katsuko Komatsu
Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25-35)-induced neuritic atrophy in cultured rat cortical neurons.
Journal of natural medicines 2011;65(3-4):417-23.
2011: Eri Joyashiki; Yuji Matsuya; Chihiro Tohda
Sominone improves memory impairments and increases axonal density in Alzheimer's disease model mice, 5XFAD.
The International journal of neuroscience 2011;121(4):181-90.
2011: Suresh Awale; Makoto Miyazaki; Yasuhiro Tezuka; Chihiro Tohda; Shigetoshi Kadota
Protective Effects of Rosa damascena and Its Active Constituent on Aβ(25-35)-Induced Neuritic Atrophy.
Evidence-based complementary and alternative medicine : eCAM 2011;2011():131042.
2010: Takuya Urano; Chihiro Tohda
Icariin improves memory impairment in Alzheimer's disease model mice (5xFAD) and attenuates amyloid β-induced neurite atrophy.
Phytotherapy research : PTR 2010;24(11):1658-63.
2009: Yuji Matsuya; Yu-ichiro Yamakawa; Chihiro Tohda; Kiyoshi Teshigawara; Masashi Yamada; Hideo Nemoto
Synthesis of sominone and its derivatives based on an RCM strategy: discovery of a novel anti-Alzheimer's disease medicine candidate "denosomin".
Organic letters 2009;11(17):3970-3.
2009: Chihiro Tohda; Eri Joyashiki
Sominone enhances neurite outgrowth and spatial memory mediated by the neurotrophic factor receptor, RET.
British journal of pharmacology 2009;157(8):1427-40.
2008: Chihiro Tohda
[Overcoming several neurodegenerative diseases by traditional medicines: the development of therapeutic medicines and unraveling pathophysiological mechanisms].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2008;128(8):1159-67.
2008: Chihiro Tohda; Mahoko Ichimura; Yanjing Bai; Ken Tanaka; Shu Zhu; Katsuko Komatsu
Inhibitory effects of Eleutherococcus senticosus extracts on amyloid beta(25-35)-induced neuritic atrophy and synaptic loss.
Journal of pharmacological sciences 2008;107(3):329-39.
2008: Chihiro Tohda; Rie Naito; Eri Joyashiki
Kihi-to, a herbal traditional medicine, improves Abeta(25-35)-induced memory impairment and losses of neurites and synapses.
BMC complementary and alternative medicine 2008;8():49.
2007: Natsuki Nakayama; Chihiro Tohda
Withanoside IV improves hindlimb function by facilitating axonal growth and increase in peripheral nervous system myelin level after spinal cord injury.
Neuroscience research 2007;58(2):176-82.
2007: Sumiyo Sasaki; Chihiro Tohda; Mujo Kim; Takako Yokozawa
Gamma-aminobutyric acid specifically inhibits progression of tubular fibrosis and atrophy in nephrectomized rats.
Biological & pharmaceutical bulletin 2007;30(4):687-91.
2006: Chihiro Tohda; T Tamura; S Matsuyama; Katsuko Komatsu
Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus.
British journal of pharmacology 2006;149(5):532-41.
2006: Hajime Fujii; Takako Yokozawa; Young Ae Kim; Chihiro Tohda; Gen-ichiro Nonaka
Protective effect of grape seed polyphenols against high glucose-induced oxidative stress.
Bioscience, biotechnology, and biochemistry 2006;70(9):2104-11.
2006: Rie Naito; Chihiro Tohda
Characterization of anti-neurodegenerative effects of Polygala tenuifolia in Abeta(25-35)-treated cortical neurons.
Biological & pharmaceutical bulletin 2006;29(9):1892-6.
2006: Chihiro Tohda; Natsuki Nakayama; Fumiyuki Hatanaka; Katsuko Komatsu
Comparison of Anti-inflammatory Activities of Six Curcuma Rhizomes: A Possible Curcuminoid-independent Pathway Mediated by Curcuma phaeocaulis Extract.
Evidence-based complementary and alternative medicine : eCAM 2006;3(2):255-60.
2006: Chihiro Tohda; Itsuki Hashimoto; Tomoharu Kuboyama; Katsuko Komatsu
Metabolite 1 of protopanaxadiol-type saponins, an axonal regenerative factor, stimulates teneurin-2 linked by PI3-kinase cascade.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(6):1158-64.
2006: Tomoharu Kuboyama; Chihiro Tohda; Katsuko Komatsu
Withanoside IV and its active metabolite, sominone, attenuate Abeta(25-35)-induced neurodegeneration.
The European journal of neuroscience 2006;23(6):1417-26.
2006: Chihiro Tohda; Ruiko Nakanishi; Makoto Kadowaki
Learning deficits and agenesis of synapses and myelinated axons in phosphoinositide-3 kinase-deficient mice.
Neuro-Signals 2006;15(6):293-306.
2005: Hyun Ju Kim; Takako Yokozawa; Hyun Young Kim; Chihiro Tohda; Theertham P Rao; Lekh Raj Juneja
Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats.
Journal of nutritional science and vitaminology 2005;51(6):413-8.
2005: Tomoharu Kuboyama; Chihiro Tohda; Katsuko Komatsu
Neuritic regeneration and synaptic reconstruction induced by withanolide A.
British journal of pharmacology 2005;144(7):961-71.
2005: Chihiro Tohda; Tomoharu Kuboyama; Katsuko Komatsu
Search for natural products related to regeneration of the neuronal network.
Neuro-Signals 2005;14(1-2):34-45.
2004: Chihiro Tohda; Noriaki Matsumoto; Kun Zou; Meselhy R Meselhy; Katsuko Komatsu
Abeta(25-35)-induced memory impairment, axonal atrophy, and synaptic loss are ameliorated by M1, A metabolite of protopanaxadiol-type saponins.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(5):860-8.
2003: Chihiro Tohda; Takayuki Tamura; Katsuko Komatsu
Repair of amyloid beta(25-35)-induced memory impairment and synaptic loss by a Kampo formula, Zokumei-to.
Brain research 2003;990(1-2):141-7.
2003: Yohei Sasaki; Hirozo Goto; Chihiro Tohda; Fumiyuki Hatanaka; Naotoshi Shibahara; Yutaka Shimada; Katsutoshi Terasawa; Katsuko Komatsu
Effects of curcuma drugs on vasomotion in isolated rat aorta.
Biological & pharmaceutical bulletin 2003;26(8):1135-43.
2003: Chihiro Tohda
Comprehensive identifying method for localized mRNAs in single neuronal axons.
Journal of biochemical and biophysical methods 2003;57(1):57-63.
2002: Chihiro Tohda; Noriaki Matsumoto; Kun Zou; Meselhy R Meselhy; Katsuko Komatsu
Axonal and dendritic extension by protopanaxadiol-type saponins from ginseng drugs in SK-N-SH cells.
Japanese journal of pharmacology 2002;90(3):254-62.
2002: Tomoharu Kuboyama; Chihiro Tohda; Jing Zhao; Norio Nakamura; Masao Hattori; Katsuko Komatsu
Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha.
Neuroreport 2002;13(14):1715-20.
2002: Kun Zou; Shu Zhu; Meselhy R Meselhy; Chihiro Tohda; Shaoqing Cai; Katsuko Komatsu
Dammarane-type Saponins from Panax japonicus and their neurite outgrowth activity in SK-N-SH cells.
Journal of natural products 2002;65(9):1288-92.
2002: Jing Zhao; Norio Nakamura; Masao Hattori; Tomoharu Kuboyama; Chihiro Tohda; Katsuko Komatsu
Withanolide derivatives from the roots of Withania somnifera and their neurite outgrowth activities.
Chemical & pharmaceutical bulletin 2002;50(6):760-5.
2002: Kun Zou; Shu Zhu; Chihiro Tohda; Shaoqing Cai; Katsuko Komatsu
Dammarane-type triterpene saponins from Panax japonicus.
Journal of natural products 2002;65(3):346-51.
2001: Purusotam Basnet; I Yasuda; N Kumagai; Chihiro Tohda; H Nojima; Yasushi Kuraishi; Katsuko Komatsu
Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice.
Biological & pharmaceutical bulletin 2001;24(9):1012-5.
2001: Chihiro Tohda; M Sasaki; T Konemura; Takashi Sasamura; M Itoh; Yasushi Kuraishi
Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation-induced increase in capsaicin sensitivity.
Journal of neurochemistry 2001;76(6):1628-35.
2000: Chihiro Tohda; Tomoharu Kuboyama; Katsuko Komatsu
Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells.
Neuroreport 2000;11(9):1981-5.
2000: Chihiro Tohda; Y Kakihara; Katsuko Komatsu; Yasushi Kuraishi
Inhibitory effects of methanol extracts of herbal medicines on substance P-induced itch-scratch response.
Biological & pharmaceutical bulletin 2000;23(5):599-601.
2000: Chihiro Tohda; H Sugahara; Yasushi Kuraishi; Katsuko Komatsu
Inhibitory effect of Byakko-ka-ninjin-to on itch in a mouse model of atopic dermatitis.
Phytotherapy research : PTR 2000;14(3):192-4.
1999: Chihiro Tohda; D M Jacobowitz
The function and expression of sproutin, a novel neurite outgrowth factor.
Neuroreport 1999;10(10):2089-94.
1999: Chihiro Tohda; Norio Nakamura; Katsuko Komatsu; Masao Hattori
Trigonelline-induced neurite outgrowth in human neuroblastoma SK-N-SH cells.
Biological & pharmaceutical bulletin 1999;22(7):679-82.
1998: M Sasaki; Chihiro Tohda; Yasushi Kuraishi
Region-specific increase in glutamate release from dorsal horn of rats with adjuvant inflammation.
Neuroreport 1998;9(14):3219-22.
1998: Takashi Sasamura; M Sasaki; Chihiro Tohda; Yasushi Kuraishi
Existence of capsaicin-sensitive glutamatergic terminals in rat hypothalamus.
Neuroreport 1998;9(9):2045-8.
1997: Chihiro Tohda; T Yamaguchi; Yasushi Kuraishi
Increased expression of mRNA for myocyte-specific enhancer binding factor (MEF) 2C in the cerebral cortex of the itching mouse.
Neuroscience research 1997;29(3):209-15.
1997: Tsugunobu Andoh; Chihiro Tohda; Yasushi Kuraishi
Analysis of dissociated single neurons by simple and semi-quantitative RT-PCR (reverse transcription and polymerase chain reaction).
Japanese journal of pharmacology 1997;74(1):121-3.
1997: Chihiro Tohda; T Yamaguchi; Yasushi Kuraishi
Intracisternal injection of opioids induces itch-associated response through mu-opioid receptors in mice.
Japanese journal of pharmacology 1997;74(1):77-82.
1996: Chihiro Tohda; S Nagai; Yasushi Kuraishi; Y Nomura
Expression of mRNA for a neuronal differentiation factor, TA2O, in developing rat brains.
Neuroscience research 1996;24(4):421-5.
1996: Chihiro Tohda; Yasushi Kuraishi
Visualization of glutamate release from rat spinal cord with a confocal laser scanning microscope.
Neuroscience research 1996;24(2):183-7.