Harukuni Tokuda

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Akihisa Toshihiro; Uchiyama Emiko; Kikuchi Takashi; Tokuda Harukuni; Suzuki Takashi; Kimura Yumiko
Anti-tumor-promoting effects of 25-methoxyporicoic acid A and other triterpene acids from Poria cocos.
Yamashita Mitsuaki; Kaneko Masafumi; Tokuda Harukuni; Nishimura Katsumi; Kumeda Yuko; Iida Akira
Synthesis and evaluation of bioactive naphthoquinones from the Brazilian medicinal plant, Tabebuia avellanedae.
Wada Shun-ichi; Yasui Yumiko; Tokuda Harukuni; Tanaka Reiko
Anti-tumor-initiating effects of phenolic compounds isolated from the bark of Picea jezoensis var. jezoensis.

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All Publications

2009: Akihisa Toshihiro; Uchiyama Emiko; Kikuchi Takashi; Tokuda Harukuni; Suzuki Takashi; Kimura Yumiko
Anti-tumor-promoting effects of 25-methoxyporicoic acid A and other triterpene acids from Poria cocos.
Journal of natural products 2009;72(10):1786-92.
2009: Yamashita Mitsuaki; Kaneko Masafumi; Tokuda Harukuni; Nishimura Katsumi; Kumeda Yuko; Iida Akira
Synthesis and evaluation of bioactive naphthoquinones from the Brazilian medicinal plant, Tabebuia avellanedae.
Bioorganic & medicinal chemistry 2009;17(17):6286-91.
2009: Wada Shun-ichi; Yasui Yumiko; Tokuda Harukuni; Tanaka Reiko
Anti-tumor-initiating effects of phenolic compounds isolated from the bark of Picea jezoensis var. jezoensis.
Bioorganic & medicinal chemistry 2009;17(17):6414-21.
2009: Iranshahi Mehrdad; Sahebkar Amirhossein; Takasaki Midori; Konoshima Takao; Tokuda Harukuni
Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2009;18(5):412-5.
2009: Dangate Milind; Franchini Laura; Ronchetti Fiamma; Arai Takanari; Iida Akira; Tokuda Harukuni; Colombo Diego
2-O-beta-d-glucopyranosyl-sn-glycerol based analogues of sulfoquinovosyldiacylglycerols (SQDG) and their role in inhibiting Epstein-Barr virus early antigen activation.
Bioorganic & medicinal chemistry 2009;17(16):5968-73.
2009: Yamaguchi Chiharu; In Yasuko; Wada Shun-ichi; Yamada Takeshi; Tokuda Harukuni; Tanaka Reiko
Cancer chemopreventive activity of oleanane-type triterpenoids from the stem bark of Betula ermanii.
Chemistry & biodiversity 2009;6(7):1093-100.
2009: Nakagawa-Goto Kyoko; Yamada Koji; Taniguchi Masahiko; Tokuda Harukuni; Lee Kuo-Hsiung
Cancer preventive agents 9. Betulinic acid derivatives as potent cancer chemopreventive agents.
Bioorganic & medicinal chemistry letters 2009;19(13):3378-81.
2009: Nishino Hoyoku; Murakoshi Michiaki; Tokuda Harukuni; Satomi Yoshiko
Cancer prevention by carotenoids.
Archives of biochemistry and biophysics 2009;483(2):165-8.
2009: Takasaki Midori; Konoshima Takao; Kozuka Mutsuo; Tokuda Harukuni; Takayasu Junko; Nishino Hoyoku; Miyakoshi Masazumi; Mizutani Kenji; Lee Kuo-Hsiung
Cancer preventive agents. Part 8: Chemopreventive effects of stevioside and related compounds.
Bioorganic & medicinal chemistry 2009;17(2):600-5.
2009: Farag Salwa F; Kimura Yuka; Ito Hideyuki; Takayasu Junko; Tokuda Harukuni; Hatano Tsutomu
New isoflavone glycosides from Iris spuria L. (Calizona) cultivated in Egypt.
Journal of natural medicines 2009;63(1):91-5.
2009: Akihisa Toshihiro; Noto Taisuke; Takahashi Akitomo; Fujita Yukiko; Banno Norihiro; Tokuda Harukuni; Koike Kazuo; Suzuki Takashi; Yasukawa Ken; Kimura Yumiko
Melanogenesis inhibitory, anti-inflammatory, and chemopreventive effects of limonoids from the seeds of Azadirachta indicia A. Juss. (neem).
Journal of oleo science 2009;58(11):581-94.
2008: Taji Sayaka; Yamada Takeshi; Wada Shun-Ichi; Tokuda Harukuni; Sakuma Kazuo; Tanaka Reiko
Lanostane-type triterpenoids from the sclerotia of Inonotus obliquus possessing anti-tumor promoting activity.
European journal of medicinal chemistry 2008;43(11):2373-9.
2008: Iwasa Kinuko; Takahashi Teturo; Nishiyama Yumi; Moriyasu Masataka; Sugiura Makiko; Takeuchi Atsuko; Tode Chisato; Tokuda Harukuni; Takeda Kazuyoshi
Online structural elucidation of alkaloids and other constituents in crude extracts and cultured cells of Nandina domestica by combination of LC-MS/MS, LC-NMR, and LC-CD analyses.
Journal of natural products 2008;71(8):1376-85.
2008: Koyama Junko; Nisino Yu; Morita Izumi; Kobayashi Norihiro; Osakai Toshiyuki; Tokuda Harukuni
Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivatives.
Bioorganic & medicinal chemistry letters 2008;18(14):4106-9.
2008: Koyama Junko; Morita Izumi; Kobayashi Norihiro; Konoshima Takao; Takasaki Midori; Osakai Toshiyuki; Tokuda Harukuni
Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids.
Cancer letters 2008;263(1):61-6.
2008: Yagura Toru; Motomiya Tomoko; Ito Michiho; Honda Gisho; Iida Akira; Kiuchi Fumiyuki; Tokuda Harukuni; Nishino Hoyoku
Anticarcinogenic compounds in the Uzbek medicinal plant, Helichrysum maracandicum.
Journal of natural medicines 2008;62(2):174-8.
2008: Tanaka Reiko; Nakata Tomoko; Yamaguchi Chiharu; Wada Shun-Ichi; Yamada Takeshi; Tokuda Harukuni
Potential anti-tumor-promoting activity of 3alpha-hydroxy-D:A-friedooleanan-2-one from the stem bark of Mallotus philippensis.
Planta medica 2008;74(4):413-6.
2008: Iranshahi Mehrdad; Kalategi Farhad; Rezaee Ramin; Shahverdi Ahmad Reza; Ito Chihiro; Furukawa Hiroshi; Tokuda Harukuni; Itoigawa Masataka
Cancer chemopreventive activity of terpenoid coumarins from Ferula species.
Planta medica 2008;74(2):147-50.
2008: Colombo Diego; Ferraboschi Patrizia; Franchini Laura; Nishino Hoyoku; Takayasu Jyunko; Tokuda Harukuni
Anti-tumor-Promoting activity of tibolone and its metabolites.
Arzneimittel-Forschung 2008;58(2):86-90.
2007: Yamashita Mitsuaki; Kaneko Masafumi; Iida Akira; Tokuda Harukuni; Nishimura Katsumi
Stereoselective synthesis and cytotoxicity of a cancer chemopreventive naphthoquinone from Tabebuia avellanedae.
Bioorganic & medicinal chemistry letters 2007;17(23):6417-20.
2007: Cui Wenhua; Iwasa Kinuko; Sugiura Makiko; Takeuchi Atsuko; Tode Chisato; Nishiyama Yumi; Moriyasu Masataka; Tokuda Harukuni; Takeda Kazuyoshi
Biotransformation of phenolic 1-benzyl-N-methyltetrahydroisoquinolines in plant cell cultures followed by LC/NMR, LC/MS, and LC/CD.
Journal of natural products 2007;70(11):1771-8.
2007: Akihisa Toshihiro; Higo Naoki; Tokuda Harukuni; Ukiya Motohiko; Akazawa Hiroyuki; Tochigi Yuichi; Kimura Yumiko; Suzuki Takashi; Nishino Hoyoku
Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects.
Journal of natural products 2007;70(8):1233-9.
2007: Ito Chihiro; Itoigawa Masataka; Kanematsu Tetsufumi; Imamura Yuuki; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Synthetic cinnamylphenol derivatives as cancer chemopreventive agents.
European journal of medicinal chemistry 2007;42(7):902-9.
2007: Kikuchi Takashi; Akihisa Toshihiro; Tokuda Harukuni; Ukiya Motohiko; Watanabe Kenji; Nishino Hoyoku
Cancer chemopreventive effects of cycloartane-type and related triterpenoids in in vitro and in vivo models.
Journal of natural products 2007;70(6):918-22.
2007: Akihisa Toshihiro; Nakamura Yuji; Tokuda Harukuni; Uchiyama Emiko; Suzuki Takashi; Kimura Yumiko; Uchikura Kazuo; Nishino Hoyoku
Triterpene acids from Poria cocos and their anti-tumor-promoting effects.
Journal of natural products 2007;70(6):948-53.
2007: Nishizawa Manabu; Ohtsu Hironori; Tanaka Reiko; Tokuda Harukuni; Katoh Takahiro; Takeo Masatoshi; Node Manabu
Oral administration of (11E)-13-oxo-15,16-dinorlabda-8(20),11-dien-19-oic acid strongly reduces photocarcinogenesis in mouse skin exposed to UV-B irradiation.
Chemistry & biodiversity 2007;4(5):1003-7.
2007: Akihisa Toshihiro; Matsumoto Kazumi; Tokuda Harukuni; Yasukawa Ken; Seino Ken-ichi; Nakamoto Katsuo; Kuninaga Hideki; Suzuki Takashi; Kimura Yumiko
Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni).
Journal of natural products 2007;70(5):754-7.
2007: Akihisa Toshihiro; Hayakawa Yosuke; Tokuda Harukuni; Banno Norihiro; Shimizu Naoto; Suzuki Takashi; Kimura Yumiko
Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein-Barr virus activation.
Journal of natural products 2007;70(5):783-8.
2007: Akihisa Toshihiro; Nakamura Yuji; Tagata Masaaki; Tokuda Harukuni; Yasukawa Ken; Uchiyama Emiko; Suzuki Takashi; Kimura Yumiko
Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidum.
Chemistry & biodiversity 2007;4(2):224-31.
2007: Nakata Tomoko; Yamada Takeshi; Taji Sayaka; Ohishi Hirofumi; Wada Shun-Ichi; Tokuda Harukuni; Sakuma Kazuo; Tanaka Reiko
Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus.
Bioorganic & medicinal chemistry 2007;15(1):257-64.
2007: Nishino Hoyoku; Satomi Yoshiko; Tokuda Harukuni; Masuda Mitsuharu
Cancer control by phytochemicals.
Current pharmaceutical design 2007;13(33):3394-9.
2006: Ukiya Motohiko; Akihisa Toshihiro; Yasukawa Ken; Tokuda Harukuni; Suzuki Takashi; Kimura Yumiko
Anti-inflammatory, anti-tumor-promoting, and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers.
Journal of natural products 2006;69(12):1692-6.
2006: Colombo Diego; Franchini Laura; Toma Lucio; Ronchetti Fiamma; Tanaka Reiko; Takayasu Junko; Nishino Hoyoku; Tokuda Harukuni
Cyclic and branched acyl chain galactoglycerolipids and their effect on anti-tumor-promoting activity.
European journal of medicinal chemistry 2006;41(12):1456-63.
2006: Akihisa Toshihiro; Tabata Keiichi; Banno Norihiro; Tokuda Harukuni; Nishimura Reiko; Nakamura Yuji; Kimura Yumiko; Yasukawa Ken; Suzuki Takashi
Cancer chemopreventive effects and cytotoxic activities of the triterpene acids from the resin of Boswellia carteri.
Biological & pharmaceutical bulletin 2006;29(9):1976-9.
2006: Banno Norihiro; Akihisa Toshihiro; Yasukawa Ken; Tokuda Harukuni; Tabata Keiichi; Nakamura Yuji; Nishimura Reiko; Kimura Yumiko; Suzuki Takashi
Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri.
Journal of ethnopharmacology 2006;107(2):249-53.
2006: Koyama Junko; Inoue Munetaka; Morita Izumi; Kobayashi Norihiro; Osakai Toshiyuki; Nishino Hoyoku; Tokuda Harukuni
Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation by emodin derivatives.
Cancer letters 2006;241(2):263-7.
2006: Fukuda Yuko; Sakai Kuniyoshi; Matsunaga Shunyo; Tokuda Harukuni; Tanaka Reiko
Cancer chemopreventive effect of orally administrated lupane-type triterpenoid on ultraviolet light B induced photocarcinogenesis of hairless mouse.
Cancer letters 2006;240(1):94-101.
2006: Tanaka Reiko; Minami Toshifumi; Tokuda Harukuni
Anti-initiating activity of 3beta-methoxy-13alpha,14alpha-epoxyserratan-21beta-ol (PJJ-34) from the stem bark of Picea jezoensis Carr. var. jezoensis.
Chemistry & biodiversity 2006;3(7):818-24.
2006: Huang Hui-Chi; Tsai Wei-Jern; Morris-Natschke Susan L; Tokuda Harukuni; Lee Kuo-Hsiung; Wu Yang-Chang; Kuo Yao-Haur
Sapinmusaponins F-J, bioactive tirucallane-type saponins from the galls of Sapindus mukorossi.
Journal of natural products 2006;69(5):763-7.
2006: Akihisa Toshihiro; Taguchi Yosuke; Yasukawa Ken; Tokuda Harukuni; Akazawa Hiroyuki; Suzuki Takashi; Kimura Yumiko
Acerogenin M, a cyclic diarylheptanoid, and other phenolic compounds from Acer nikoense and their anti-inflammatory and anti-tumor-promoting effects.
Chemical & pharmaceutical bulletin 2006;54(5):735-9.
2006: Horiuchi Masayuki; Tokuda Harukuni; Ohnishi Keiichiro; Yamashita Masakazu; Nishino Hoyoku; Maoka Takashi
Porritoxins, metabolites of Alternaria porri, as anti-tumor-promoting active compounds.
Natural product research 2006;20(2):161-6.
2006: Akihisa Toshihiro; Tokuda Harukuni; Hasegawa Daisuke; Ukiya Motohiko; Kimura Yumiko; Enjo Fumio; Suzuki Takashi; Nishino Hoyoku
Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects.
Journal of natural products 2006;69(1):38-42.
2006: Cui Wenhua; Iwasa Kinuko; Tokuda Harukuni; Kashihara Akiko; Mitani Yosuke; Hasegawa Tomoko; Nishiyama Yumi; Moriyasu Masataka; Nishino Hoyoku; Hanaoka Miyoji; Mukai Chisato; Takeda Kazuyoshi
Potential cancer chemopreventive activity of simple isoquinolines, 1-benzylisoquinolines, and protoberberines.
Phytochemistry 2006;67(1):70-9.
2006: Ishikawa Takeshi; Yoshida Norimasa; Tokuda Harukuni; Kokura Satoshi; Nakabe Nami; Kuchide Masashi; Ichiishi Eiichiro; Imaeda Atsumune; Ichikawa Hiroshi; Naito Yuji; Okanoue Takeshi; Yoshikawa Toshikazu
Role of oxygen-derived free radicals in Helicobacter pylori water extract-induced mouse skin carcinogenesis.
BioFactors (Oxford, England) 2006;28(1):1-7.
2005: Akihisa Toshihiro; Tokuda Harukuni; Ukiya Motohiko; Kiyota Ayaka; Yasukawa Ken; Sakamoto Naoyuki; Kimura Yumiko; Suzuki Takashi; Takayasu Junko; Nishino Hoyoku
Anti-tumor-initiating effects of monascin, an azaphilonoid pigment from the extract of Monascus pilosus fermented rice (red-mold rice).
Chemistry & biodiversity 2005;2(10):1305-9.
2005: Banno Norihiro; Akihisa Toshihiro; Tokuda Harukuni; Yasukawa Ken; Taguchi Yosuke; Akazawa Hiroyuki; Ukiya Motohiko; Kimura Yumiko; Suzuki Takashi; Nishino Hoyoku
Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica.
Biological & pharmaceutical bulletin 2005;28(10):1995-9.
2005: Koyama Junko; Morita Izumi; Kobayashi Norihiro; Osakai Toshiyuki; Nishino Hoyoku; Tokuda Harukuni
Correlation between reduction potentials and inhibitory effects on Epstein-Barr virus activation of poly-substituted anthraquinones.
Cancer letters 2005;225(2):193-8.
2005: Nakamura Seikou; Kozuka Mutsuo; Bastow Kenneth F; Tokuda Harukuni; Nishino Hoyoku; Suzuki Madoka; Tatsuzaki Jin; Morris Natschke Susan L; Kuo Sheng-Chu; Lee Kuo-Hsiung
Cancer preventive agents, Part 2: Synthesis and evaluation of 2-phenyl-4-quinolone and 9-oxo-9,10-dihydroacridine derivatives as novel antitumor promoters.
Bioorganic & medicinal chemistry 2005;13(14):4396-401.
2005: Akihisa Toshihiro; Franzblau Scott Gary; Tokuda Harukuni; Tagata Masaaki; Ukiya Motohiko; Matsuzawa Tsunetomo; Metori Koichi; Kimura Yumiko; Suzuki Takashi; Yasukawa Ken
Antitubercular activity and inhibitory effect on Epstein-Barr virus activation of sterols and polyisoprenepolyols from an edible mushroom, Hypsizigus marmoreus.
Biological & pharmaceutical bulletin 2005;28(6):1117-9.
2005: Nakagawa-Goto Kyoko; Bastow Kenneth F; Wu Jiu-Hong; Tokuda Harukuni; Lee Kuo-Hsiung
Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs.
Bioorganic & medicinal chemistry letters 2005;15(12):3016-9.
2005: Kimura Yumiko; Akihisa Toshihiro; Yuasa Noriko; Ukiya Motohiko; Suzuki Takashi; Toriyama Masaharu; Motohashi Shigeyasu; Tokuda Harukuni
Cucurbitane-type triterpenoids from the fruit of Momordica charantia.
Journal of natural products 2005;68(5):807-9.
2005: Akihisa Toshihiro; Tagata Masaaki; Ukiya Motohiko; Tokuda Harukuni; Suzuki Takashi; Kimura Yumiko
Oxygenated lanostane-type triterpenoids from the fungus ganodermalucidum.
Journal of natural products 2005;68(4):559-63.
2005: Fukuda Yuko; Sakai Kuniyoshi; Matsunaga Shunyo; Tokuda Harukuni; Tanaka Reiko
Cancer chemopreventive activity of lupane- and oleanane-type triterpenoids from the cones of Liquidamber styraciflua.
Chemistry & biodiversity 2005;2(3):421-8.
2005: Ito Chihiro; Itoigawa Masataka; Onoda Saori; Hosokawa Atsuko; Ruangrungsi Nijsiri; Okuda Toshimitsu; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Chemical constituents of Murraya siamensis: three coumarins and their anti-tumor promoting effect.
Phytochemistry 2005;66(5):567-72.
2005: Mendoza Cristina R; Jiménez Ignacio A; Tokuda Harukuni; Kushida Hiroyuki; Bazzocchi Isabel L
Antitumor-promoting effects of new sesquiterpenes from Crossopetalum tonduzii.
Chemistry & biodiversity 2005;2(2):286-94.
2005: Akihisa Toshihiro; Tokuda Harukuni; Yasukawa Ken; Ukiya Motohiko; Kiyota Ayaka; Sakamoto Naoyuki; Suzuki Takashi; Tanabe Nobukazu; Nishino Hoyoku
Azaphilones, furanoisophthalides, and amino acids from the extracts of Monascus pilosus-fermented rice (red-mold rice) and their chemopreventive effects.
Journal of agricultural and food chemistry 2005;53(3):562-5.
2005: Sakurai Nobuko; Kozuka Mutsuo; Tokuda Harukuni; Mukainaka Teruo; Enjo Fumio; Nishino Hoyoku; Nagai Masahiro; Sakurai Yojiro; Lee Kuo-Hsiung
Cancer preventive agents. Part 1: chemopreventive potential of cimigenol, cimigenol-3,15-dione, and related compounds.
Bioorganic & medicinal chemistry 2005;13(4):1403-8.
2005: Ito Chihiro; Itoigawa Masataka; Ju-ichi Motoharu; Sakamoto Naoyuki; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Antitumor-promoting activity of coumarins from citrus plants.
Planta medica 2005;71(1):84-7.
2005: Colombo Diego; Franchini Laura; Toma Lucio; Ronchetti Fiamma; Nakabe Nami; Konoshima Takako; Nishino Hoyoku; Tokuda Harukuni
Anti-tumor-promoting activity of simple models of galactoglycerolipids with branched and unsaturated acyl chains.
European journal of medicinal chemistry 2005;40(1):69-74.
2004: Tanaka Reiko; Kinouchi Yoshitaka; Wada Shun-ichi; Tokuda Harukuni
Potential anti-tumor promoting activity of lupane-type triterpenoids from the stem bark of Glochidion zeylanicum and Phyllanthus flexuosus.
Planta medica 2004;70(12):1234-6.
2004: Aoi Wataru; Ichiishi Eiichiro; Sakamoto Naoyuki; Tsujimoto Atsumi; Tokuda Harukuni; Yoshikawa Toshikazu
Effect of exercise on hepatic gene expression in rats: a microarray analysis.
Life sciences 2004;75(26):3117-28.
2004: Itoigawa Masataka; Ito Chihiro; Tokuda Harukuni; Enjo Fumio; Nishino Hoyoku; Furukawa Hiroshi
Cancer chemopreventive activity of phenylpropanoids and phytoquinoids from Illicium plants.
Cancer letters 2004;214(2):165-9.
2004: Tanaka Reiko; Shanmugasundaram Kandasamy; Yamaguchi Chiharu; Ishikawa Yohei; Tokuda Harukuni; Nishide Kiyoharu; Node Manabu
Cancer chemopreventive activity of 3beta-methoxyserrat-14-en-21beta-ol and several serratane analogs on two-stage mouse skin carcinogenesis.
Cancer letters 2004;214(2):149-56.
2004: Tanaka Reiko; Wada Shun-ichi; Kinouchi Yoshitaka; Tokuda Harukuni; Matsunaga Shunyo
A new seco-abietane-type diterpene from the stem bark of Picea glehni.
Planta medica 2004;70(9):877-80.
2004: Ito Chihiro; Itoigawa Masataka; Sato Atsuko; Hasan Choudhury M; Rashid Mohammad A; Tokuda Harukuni; Mukainaka Teruo; Nishino Hoyoku; Furukawa Hiroshi
Chemical constituents of Glycosmis arborea: three new carbazole alkaloids and their biological activity.
Journal of natural products 2004;67(9):1488-91.
2004: Murakami Chihiro; Fukamiya Narihiko; Tamura Sadaaki; Okano Masayoshi; Bastow Kenneth F; Tokuda Harukuni; Mukainaka Teruo; Nishino Hoyoky; Lee Kuo-Hsiung
Multidrug-resistant cancer cell susceptibility to cytotoxic quassinoids, and cancer chemopreventive effects of quassinoids and canthin alkaloids.
Bioorganic & medicinal chemistry 2004;12(18):4963-8.
2004: Koyama Junko; Morita Izumi; Kobayashi Norihiro; Osakai Toshiyuki; Hotta Hiroki; Takayasu Junko; Nishino Hoyoku; Tokuda Harukuni
Correlation of redox potentials and inhibitory effects on Epstein-Barr virus activation of 2-azaanthraquinones.
Cancer letters 2004;212(1):1-6.
2004: Ito Chihiro; Itoigawa Masataka; Kojima Naoki; Tokuda Harukuni; Hirata Tetsurou; Nishino Hoyoku; Furukawa Hiroshi
Chemical constituents of Millettia taiwaniana: structure elucidation of five new isoflavonoids and their cancer chemopreventive activity.
Journal of natural products 2004;67(7):1125-30.
2004: Tanaka Reiko; Minami Toshifumi; Ishikawa Yohei; Tokuda Harukuni; Matsunaga Shunyo
Cancer chemopreventive activity of serratane-type triterpenoids from Picea jezoensis.
Chemistry & biodiversity 2004;1(6):878-85.
2004: Ito Chihiro; Itoigawa Masataka; Kojima Naoki; Tan Hugh T-W; Takayasu Junko; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Cancer chemopreventive activity of rotenoids from Derris trifoliata.
Planta medica 2004;70(6):585-8.
2004: Akihisa Toshihiro; Mafune Shoichi; Ukiya Motohiko; Kimura Yumiko; Yasukawa Ken; Suzuki Takashi; Tokuda Harukuni; Tanabe Nobukazu; Fukuoka Tadahiko
(+)- and (-)-syn-2-isobutyl-4-methylazetidine-2,4-dicarboxylic acids from the extract of Monascus pilosus-fermented rice (red-mold rice).
Journal of natural products 2004;67(3):479-80.
2004: Ito Hideyuki; Kasajima Naoki; Tokuda Harukuni; Nishino Hoyoku; Yoshida Takashi
Dimeric flavonol glycoside and galloylated C-glucosylchromones from Kunzea ambigua.
Journal of natural products 2004;67(3):411-5.
2004: Akihisa Toshihiro; Hamasaki Yusuke; Tokuda Harukuni; Ukiya Motohiko; Kimura Yumiko; Nishino Hoyoku
Microbial transformation of isosteviol and inhibitory effects on Epstein-Barr virus activation of the transformation products.
Journal of natural products 2004;67(3):407-10.
2004: Akihisa Toshihiro; Tokuda Harukuni; Ogata Masakazu; Ukiya Motohiko; Iizuka Masao; Suzuki Takashi; Metori Koichi; Shimizu Naoto; Nishino Hoyoku
Cancer chemopreventive effects of polyunsaturated fatty acids.
Cancer letters 2004;205(1):9-13.
2004: Azuine Magnus A; Tokuda Harukuni; Takayasu Junko; Enjyo Fumio; Mukainaka Teruo; Konoshima Takao; Nishino Hoyoku; Kapadia Govind J
Cancer chemopreventive effect of phenothiazines and related tri-heterocyclic analogues in the 12-O-tetradecanoylphorbol-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse skin two-stage carcinogenesis models.
Pharmacological research : the official journal of the Italian Pharmacological Society 2004;49(2):161-9.
2004: Ito Chihiro; Itoigawa Masataka; Kojima Naoki; Tan Hugh T-W; Takayasu Junko; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Cancer chemopreventive activity of rotenoids from Derris trifoliata.
Planta medica 2004;70(1):8-11.
2004: Banno Norihiro; Akihisa Toshihiro; Tokuda Harukuni; Yasukawa Ken; Higashihara Hiroshi; Ukiya Motohiko; Watanabe Kenji; Kimura Yumiko; Hasegawa Jun-Ichi; Nishino Hoyoku
Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects.
Bioscience, biotechnology, and biochemistry 2004;68(1):85-90.
2004: Akihisa Toshihiro; Tokuda Harukuni; Ukiya Motohiko; Suzuki Toshie; Enjo Fumio; Koike Kazuo; Nikaido Tamotsu; Nishino Hoyoku
3-epicabraleahydroxylactone and other triterpenoids from camellia oil and their inhibitory effects on Epstein-Barr virus activation.
Chemical & pharmaceutical bulletin 2004;52(1):153-6.
2004: Suzuki Rikako; Kohno Hiroyuki; Murakami Akira; Koshimizu Koichi; Ohigashi Hajime; Yano Masamichi; Tokuda Harukuni; Nishino Hoyoku; Tanaka Takuji
Citrus nobiletin inhibits azoxymethane-induced large bowel carcinogenesis in rats.
BioFactors (Oxford, England) 2004;22(1-4):111-4.
2004: Nishino Hoyoku; Tokuda Harukuni; Satomi Yoshiko; Masuda Mitsuharu; Osaka Yasuhito; Yogosawa Shingo; Wada Saeri; Mou Xiao Yang; Takayasu Junko; Murakoshi Michiaki; Jinnno Kenji; Yano Masamichi
Cancer prevention by antioxidants.
BioFactors (Oxford, England) 2004;22(1-4):57-61.
2003: Iwatsuki Kenji; Akihisa Toshihiro; Tokuda Harukuni; Ukiya Motohiko; Oshikubo Manabu; Kimura Yumiko; Asano Takeshi; Nomura Atsushi; Nishino Hoyoku
Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation.
Journal of natural products 2003;66(12):1582-5.
2003: Ito Chihiro; Itoigawa Masataka; Kanematsu Tetsufumi; Ruangrungsi Nijsiri; Higashihara Hiroshi; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
New cinnamylphenols from Dalbergia species with cancer chemopreventive activity.
Journal of natural products 2003;66(12):1574-7.
2003: Uesato Shinichi; Taniuchi Keisuke; Kumagai Ayako; Nagaoka Yasuo; Seto Ryota; Hara Yukihiko; Tokuda Harukuni; Nishino Hoyoku
Inhibitory effects of 3-O-acyl-(+)-catechins on Epstein-Barr virus activation.
Chemical & pharmaceutical bulletin 2003;51(12):1448-50.
2003: Ito Chihiro; Itoigawa Masataka; Kanematsu Tetsufumi; Ruangrungsi Nijsiri; Mukainaka Teruo; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Isoflavonoids from Dalbergia olivari.
Phytochemistry 2003;64(7):1265-8.
2003: Tanaka Reiko; Ishikawa Yohei; Minami Toshifumi; Minoura Katsuhiko; Tokuda Harukuni; Matsunaga Shunyo
Two new anti-tumor promoting serratane-type triterpenoids from the stem bark of Picea jezoensis var. jezoensis.
Planta medica 2003;69(11):1041-7.
2003: Ukiya Motohiko; Akihisa Toshihiro; Tokuda Harukuni; Koike Kazuo; Kimura Yumiko; Asano Takeshi; Motohashi Shigeyasu; Nikaido Tamotsu; Nishino Hoyoku
Sunpollenol and five other rearranged 3,4-seco-tirucallane-type triterpenoids from sunflower pollen and their inhibitory effects on Epstein-Barr virus activation.
Journal of natural products 2003;66(11):1476-9.
2003: Akihisa Toshihiro; Tokuda Harukuni; Ukiya Motohiko; Iizuka Masao; Schneider Stefan; Ogasawara Kazuya; Mukainaka Teruo; Iwatsuki Kenji; Suzuki Takashi; Nishino Hoyoku
Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects.
Cancer letters 2003;201(2):133-7.
2003: Kumagai Ayako; Nagaoka Yasuo; Obayashi Tomoko; Terashima Yasuhiro; Tokuda Harukuni; Hara Yukihiko; Mukainaka Teruo; Nishino Hoyoku; Kuwajima Hiroshi; Uesato Shinichi
Tumor chemopreventive activity of 3-O-acylated (--)-epigallocatechins.
Bioorganic & medicinal chemistry 2003;11(23):5143-8.
2003: Iwatsuki Kenji; Akihisa Toshihiro; Tokuda Harukuni; Ukiya Motohiko; Higashihara Hiroshi; Mukainaka Teruo; Iizuka Masao; Hayashi Yoshiharu; Kimura Yumiko; Nishino Hoyoku
Sterol ferulates, sterols, and 5-alk(en)ylresorcinols from wheat, rye, and corn bran oils and their inhibitory effects on Epstein-Barr virus activation.
Journal of agricultural and food chemistry 2003;51(23):6683-8.
2003: Koyama Junko; Morita Izumi; Kobayashi Norihiro; Osakai Toshiyuki; Hotta Hiroki; Takayasu Junko; Nishino Hoyoku; Tokuda Harukuni
Correlation of redox potentials and inhibitory effects on Epstein-Barr virus activation of naphthoquinones.
Cancer letters 2003;201(1):25-30.
2003: Ismail Intan Safinar; Ito Hideyuki; Mukainaka Teruo; Higashihara Hiroshi; Enjo Fumio; Tokuda Harukuni; Nishino Hoyoku; Yoshida Takashi
Ichthyotoxic and anticarcinogenic effects of triterpenoids from Sandoricum koetjape bark.
Biological & pharmaceutical bulletin 2003;26(9):1351-3.
2003: Kuroda Junya; Kimura Shinya; Segawa Hidekazu; Kobayashi Yutaka; Yoshikawa Toshikazu; Urasaki Yoshimasa; Ueda Takanori; Enjo Fumio; Tokuda Harukuni; Ottmann Oliver G; Maekawa Taira
The third-generation bisphosphonate zoledronate synergistically augments the anti-Ph+ leukemia activity of imatinib mesylate.
Blood 2003;102(6):2229-35.
2003: Jiménez Ignacio A; Bazzocchi Isabel L; Núñez Marvin J; Mukainaka Teruo; Tokuda Harukuni; Nishino Hoyoku; Konoshima Takao; Ravelo Angel G
Absolute configuration of sesquiterpenes from Crossopetalum tonduzii and their inhibitory effects on Epstein-Barr virus early antigen activation in Raji cells.
Journal of natural products 2003;66(8):1047-50.
2003: Takasaki Midori; Konoshima Takao; Murata Yuji; Sugiura Masaki; Nishino Hoyoku; Tokuda Harukuni; Matsumoto Kazuhiro; Kasai Ryoji; Yamasaki Kazuo
Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori.
Cancer letters 2003;198(1):37-42.
2003: Kuchide Masashi; Tokuda Harukuni; Takayasu Junko; Enjo Fumio; Ishikawa Takeshi; Ichiishi Eiichiro; Naito Yuji; Yoshida Norimasa; Yoshikawa Toshikazu; Nishino Hoyoku
Cancer chemopreventive effects of oral feeding alpha-tocopherol on ultraviolet light B induced photocarcinogenesis of hairless mouse.
Cancer letters 2003;196(2):169-77.
2003: Tanaka Reiko; Minami Toshifumi; Ishikawa Yohei; Matsunaga Shunyo; Tokuda Harukuni; Nishino Hoyoku
Cancer chemopreventive activity of serratane-type triterpenoids on two-stage mouse skin carcinogenesis.
Cancer letters 2003;196(2):121-6.
2003: Satomi Yoshiko; Bu Ping; Okuda Masato; Tokuda Harukuni; Nishino Hoyoku
H-ras mutations at codon 61 or 13 in tumors initiated with a NO donor in mouse skin.
Cancer letters 2003;196(1):17-22.
2003: Konishi Kazuhide; Iida Akira; Kaneko Masafumi; Tomioka Kiyoshi; Tokuda Harukuni; Nishino Hoyoku; Kumeda Yuko
Cancer preventive potential of trichothecenes from Trichothecium roseum.
Bioorganic & medicinal chemistry 2003;11(12):2511-8.
2003: Ukiya Motohiko; Akihisa Toshihiro; Tokuda Harukuni; Koike Kazuo; Takayasu Junko; Okuda Hiroki; Kimura Yumiko; Nikaido Tamotsu; Nishino Hoyoku
Isolation, structural elucidation, and inhibitory effects of terpenoid and lipid constituents from sunflower pollen on Epstein-Barr virus early antigen induced by tumor promoter, TPA.
Journal of agricultural and food chemistry 2003;51(10):2949-57.
2003: Brantner A H; Asres K; Chakraborty A; Tokuda H; Mou X Y; Mukainaka T; Nishino H; Stoyanova S; Hamburger M
Crown gall -- a plant tumour with biological activities.
Phytotherapy research : PTR 2003;17(4):385-90.
2003: Itoigawa Masataka; Ito Chihiro; Wu Tian-Shung; Enjo Fumio; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Cancer chemopreventive activity of acridone alkaloids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 2003;193(2):133-8.
2003: Tamura Sadaaki; Fukamiya Narihiko; Okano Masayoshi; Koyama Junko; Koike Kazuo; Tokuda Harukuni; Aoi Wataru; Takayasu Junko; Kuchide Masashi; Nishino Hoyoku
Three new quassinoids, ailantinol E, F, and G, from Ailanthus altissima.
Chemical & pharmaceutical bulletin 2003;51(4):385-9.
2003: Ito Chihiro; Itoigawa Masataka; Mishina Yoshitaka; Filho Valdir Cechinel; Enjo Fumio; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Chemical constituents of Calophyllum brasiliense. 2. Structure of three new coumarins and cancer chemopreventive activity of 4-substituted coumarins.
Journal of natural products 2003;66(3):368-71.
2003: Sakurai Nobuko; Kozuka Mutsuo; Tokuda Harukuni; Nobukuni Yoshitaka; Takayasu Junko; Nishino Hoyoku; Kusano Akiko; Kusano Genjiro; Nagai Masahiro; Sakurai Yojiro; Lee Kuo Hsiung
Antitumor agents 220. Antitumor-promoting effects of cimigenol and related compounds on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Bioorganic & medicinal chemistry 2003;11(6):1137-40.
2003: Colombo Diego; Ronchetti Fiamma; Scala Antonio; Toma Lucio; Tokuda Harukuni; Nishino Hoyoku
Synthesis and anti-tumor-promoting activity of glycoglycerolipid analogues lacking the glycerol backbone.
Bioorganic & medicinal chemistry 2003;11(6):909-12.
2003: Aoi Wataru; Naito Yuji; Sakuma Kunihiro; Kuchide Masashi; Tokuda Harukuni; Maoka Takashi; Toyokuni Shinya; Oka Shigenori; Yasuhara Masahiro; Yoshikawa Toshikazu
Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice.
Antioxidants & redox signaling 2003;5(1):139-44.
2003: Ishikawa Takeshi; Yoshida Norimasa; Tokuda Harukuni; Ichiishi Eiichiro; Kuchide Masashi; Kokura Satoshi; Naito Yuji; Toyokuni Shinya; Nishino Hoyoku; Yoshikawa Toshikazu
Tumor initiating activity of Helicobacter pylori water extract on mouse skin carcinogenesis.
Cancer letters 2003;191(1):41-7.
2003: Ito Chihiro; Itoigawa Masataka; Miyamoto Yoshiaki; Onoda Saori; Rao K Sundar; Mukainaka Teruo; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Polyprenylated benzophenones from Garcinia assigu and their potential cancer chemopreventive activities.
Journal of natural products 2003;66(2):206-9.
2003: Ito Chihiro; Itoigawa Masataka; Takakura Tomoko; Ruangrungsi Nijisiri; Enjo Fumio; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Chemical constituents of Garcinia fusca: structure elucidation of eight new xanthones and their cancer chemopreventive activity.
Journal of natural products 2003;66(2):200-5.
2003: Fukuda Toshiyuki; Ito Hideyuki; Mukainaka Teruo; Tokuda Harukuni; Nishino Hoyoku; Yoshida Takashi
Anti-tumor promoting effect of glycosides from Prunus persica seeds.
Biological & pharmaceutical bulletin 2003;26(2):271-3.
2003: Kapadia Govind J; Azuine Magnus A; Sridhar Rajagopalan; Okuda Yoko; Tsuruta Atsushi; Ichiishi Eiichiro; Mukainake Teruo; Takasaki Midori; Konoshima Takao; Nishino Hoyoku; Tokuda Harukuni
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot.
Pharmacological research : the official journal of the Italian Pharmacological Society 2003;47(2):141-8.
2003: Iwamoto Manabu; Minami Toshifumi; Tokuda Harukuni; Ohtsu Hironori; Tanaka Reiko
Potential antitumor promoting diterpenoids from the stem bark of Thuja standishii.
Planta medica 2003;69(1):69-72.
2002: Minami Toshifumi; Wada Shun-ichi; Tokuda Harukuni; Tanabe Genzoh; Muraoka Osamu; Tanaka Reiko
Potential antitumor-promoting diterpenes from the cones of Pinus luchuensis.
Journal of natural products 2002;65(12):1921-3.
2002: Colombo Diego; Compostella Federica; Ronchetti Fiamma; Reza-Elahi Shahrzad; Scala Antonio; Toma Lucio; Aoi Wataru; Kuchide Masashi; Takayasu Junko; Tokuda Harukuni; Nishino Hoyoku
Inhibitory effect of stabilized analogues of glycoglycerolipids on Epstein-Barr virus activation and mouse skin tumor promotion.
Cancer letters 2002;186(1):37-41.
2002: Ukiya Motohiko; Akihisa Toshihiro; Tokuda Harukuni; Toriumi Masakazu; Mukainaka Teruo; Banno Norihiro; Kimura Yumiko; Hasegawa Jun-Ichi; Nishino Hoyoku
Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Journal of agricultural and food chemistry 2002;50(23):6710-5.
2002: Tamura Sadaaki; Fukamiya Narihiko; Okano Masayoshi; Tokuda Harukuni; Aoi Wataru; Mukainaka Teruo; Nishino Hoyoku; Tagahara Kiyoshi; Koike Kazuo
Cancer chemopreventive effect of quassinoid derivatives. Introduction of side chain to shinjulactone C for enhancement of inhibitory effect on Epstein-Barr virus activation.
Cancer letters 2002;185(1):47-51.
2002: Ishida Junko; Kozuka Mutsuo; Tokuda Harukuni; Nishino Hoyoku; Nagumo Seiji; Lee Kuo Hsiung; Nagai Masahiro
Chemopreventive potential of cyclic diarylheptanoids.
Bioorganic & medicinal chemistry 2002;10(10):3361-5.
2002: Chen Dao-Feng; Zhang Shun-Xiang; Kozuka Mutsuo; Sun Quan-Zhong; Feng Ju; Wang Qiang; Mukainaka Teruo; Nobukuni Yoshitaka; Tokuda Harukuni; Nishino Hoyoku; Wang Hui-Kang; Morris-Natschke Susan L; Lee Kuo-Hsiung
Interiotherins C and D, two new lignans from Kadsura interior and antitumor-promoting effects of related neolignans on Epstein-Barr virus activation.
Journal of natural products 2002;65(9):1242-5.
2002: Koyama Junko; Morita Izumi; Tagahara Kiyoshi; Nobukuni Yoshitaka; Mukainaka Teruo; Kuchide Masashi; Tokuda Harukuni; Nishino Hoyoku
Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis.
Cancer letters 2002;182(2):135-9.
2002: Kapadia Govind J; Azuine Magnus A; Tokuda Harukuni; Takasaki Midori; Mukainaka Teruo; Konoshima Takao; Nishino Hoyoku
Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis.
Pharmacological research : the official journal of the Italian Pharmacological Society 2002;45(6):499-505.
2002: Nakamura Eliane S; Kurosaki Fumiya; Arisawa Munehisa; Mukainaka Teruo; Takayasu Junko; Okuda Masato; Tokuda Harukuni; Nishino Hoyoku; Pastore Floriano
Cancer chemopreventive effects of a Brazilian folk medicine, Juca, on in vivo two-stage skin carcinogenesis.
Journal of ethnopharmacology 2002;81(1):135-7.
2002: Ukiya Motohiko; Akihisa Toshihiro; Tokuda Harukuni; Hirano Masaya; Oshikubo Manabu; Nobukuni Yoshitoshi; Kimura Yumiko; Tai Takaaki; Kondo Seizo; Nishino Hoyoku
Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos.
Journal of natural products 2002;65(4):462-5.
2002: Ito Hideyuki; Kobayashi Eri; Li Shu-Hua; Hatano Tsutomu; Sugita Daigo; Kubo Naoki; Shimura Susumu; Itoh Yoshio; Tokuda Harukuni; Nishino Hoyoku; Yoshida Takashi
Antitumor activity of compounds isolated from leaves of Eriobotrya japonica.
Journal of agricultural and food chemistry 2002;50(8):2400-3.
2002: Akihisa Toshihiro; Takamine Yoshio; Yoshizumi Kazuo; Tokuda Harukuni; Kimura Yumiko; Ukiya Motohiko; Nakahara Toro; Yokochi Toshihiro; Ichiishi Eiichiro; Nishino Hoyoku
Microbial transformations of two lupane-type triterpenes and anti-tumor-promoting effects of the transformation products.
Journal of natural products 2002;65(3):278-82.
2002: Ito Chihiro; Itoigawa Masataka; Mishina Yoshitaka; Filho Valdir Cechinel; Mukainaka Teruo; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Chemical constituents of Calophyllum brasiliensis: structure elucidation of seven new xanthones and their cancer chemopreventive activity.
Journal of natural products 2002;65(3):267-72.
2002: Kapadia Govind J; Azuine Magnus A; Tokuda Harukuni; Hang Eric; Mukainaka T; Nishino Hoyoku; Sridhar Rajagopalan
Inhibitory effect of herbal remedies on 12-O-tetradecanoylphorbol-13-acetate-promoted Epstein-Barr virus early antigen activation.
Pharmacological research : the official journal of the Italian Pharmacological Society 2002;45(3):213-20.
2002: Nakamura Eliane S; Kurosaki Fumiya; Arisawa Munehisa; Mukainaka Teruo; Okuda Masato; Tokuda Harukuni; Nishino Hoyoku; Pastore Floriano
Cancer chemopreventive effects of constituents of Caesalpinia ferrea and related compounds.
Cancer letters 2002;177(2):119-24.
2002: Ukiya Motohiko; Akihisa Toshihiro; Tokuda Harukuni; Suzuki Hiroyuki; Mukainaka Teruo; Ichiishi Eiichiro; Yasukawa Ken; Kasahara Yoshimasa; Nishino Hoyoku
Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers.
Cancer letters 2002;177(1):7-12.
2002: Chakraborty Asima; Brantner Adelheid; Mukainaka Teruo; Nobukuni Yoshitoshi; Kuchide Masashi; Konoshima Takao; Tokuda Harukuni; Nishino Hoyoku
Cancer chemopreventive activity of Achyranthes aspera leaves on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 2002;177(1):1-5.
2002: Ukiya Motohiko; Akihisa Toshihiro; Yasukawa Ken; Tokuda Harukuni; Toriumi Masakazu; Koike Kazuo; Kimura Yumiko; Nikaido Tamotsu; Aoi Wataru; Nishino Hoyoku; Takido Michio
Anti-inflammatory and anti-tumor-promoting effects of cucurbitane glycosides from the roots of Bryonia dioica.
Journal of natural products 2002;65(2):179-83.
2002: Akihisa Toshihiro; Kithsiri Wijeratne E M; Tokuda Harukuni; Enjo Fumio; Toriumi Masakazu; Kimura Yumiko; Koike Kazuo; Nikaido Tamotsu; Tezuka Yasuhiro; Nishino Hoyoku
Eupha-7,9(11),24-trien-3beta-ol ("antiquol C") and other triterpenes from Euphorbia antiquorum latex and their inhibitory effects on Epstein-Barr virus activation.
Journal of natural products 2002;65(2):158-62.
2002: Baba Masaki; Jin Yongri; Mizuno Atsuo; Suzuki Hisaya; Okada Yoshihito; Takasuka Nobuo; Tokuda Harukuni; Nishino Hoyoku; Okuyama Toru
Studies on cancer chemoprevention by traditional folk medicines XXIV. Inhibitory effect of a coumarin derivative, 7-isopentenyloxycoumarin, against tumor-promotion.
Biological & pharmaceutical bulletin 2002;25(2):244-6.
2002: Taniguchi Shoko; Imayoshi Yoko; Kobayashi Eri; Takamatsu Yoshie; Ito Hideyuki; Hatano Tsutomu; Sakagami Hiroshi; Tokuda Harukuni; Nishino Hoyoku; Sugita Daigo; Shimura Susumu; Yoshida Takashi
Production of bioactive triterpenes by Eriobotrya japonica calli.
Phytochemistry 2002;59(3):315-23.
2002: Itoigawa Masataka; Ito Chihiro; Ju-ichi Motoharu; Nobukuni Toshihiro; Ichiishi Eiichiro; Tokuda Harukuni; Nishino Hoyoku; Furukawa Hiroshi
Cancer chemopreventive activity of flavanones on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 2002;176(1):25-9.
2001: Konoshima T; Konishi T; Takasaki M; Yamazoe K; Tokuda H
Anti-tumor-promoting activity of the diterpene from Excoecaria agallocha. II.
Biological & pharmaceutical bulletin 2001;24(12):1440-2.
2001: Nishino H; Tokuda H; Ii T; Takemura M; Kuchide M; Kanazawa M; Mou X Y; Bu P; Takayasu J; Onozuka M; Masuda M; Satomi Y; Konoshima T; Kishi N; Baba M; Okada Y; Okuyama T
Cancer chemoprevention by ginseng in mouse liver and other organs.
Journal of Korean medical science 2001;16 Suppl():S66-9.
2001: Itoigawa M; Ito C; Tan H T; Okuda M; Tokuda H; Nishino H; Furukawa H
Cancer chemopreventive activity of naphthoquinones and their analogs from Avicennia plants.
Cancer letters 2001;174(2):135-9.
2001: Inad A; Nishino H; Kuchide M; Takayasu J; Mukainaka T; Nobukuni Y; Okuda M; Tokuda H
Cancer chemopreventive activity of odorine and odorinol from Aglaia odorata.
Biological & pharmaceutical bulletin 2001;24(11):1282-5.
2001: Iwase Y; Takemura Y; Ju-ichi M; Mukainaka T; Ichiishi E; Ito C; Furukawa H; Yano M; Tokuda H; Nishino H
Inhibitory effect of flavonoid derivatives on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
Cancer letters 2001;173(2):105-9.
2001: Akihisa T; Tokuda H; Ichiishi E; Mukainaka T; Toriumi M; Ukiya M; Yasukawa K; Nishino H
Anti-tumor promoting effects of multiflorane-type triterpenoids and cytotoxic activity of karounidiol against human cancer cell lines.
Cancer letters 2001;173(1):9-14.
2001: Tanaka R; Minami T; Tsujimoto K; Matsunaga S; Tokuda H; Nishino H; Terada Y; Yoshitake A
Cancer chemopreventive agents, serratane-type triterpenoids from Picea jezoensis.
Cancer letters 2001;172(2):119-26.
2001: Maoka T; Mochida K; Kozuka M; Ito Y; Fujiwara Y; Hashimoto K; Enjo F; Ogata M; Nobukuni Y; Tokuda H; Nishino H
Cancer chemopreventive activity of carotenoids in the fruits of red paprika Capsicum annuum L.
Cancer letters 2001;172(2):103-9.
2001: Koyama J; Morita I; Tagahara K; Ogata M; Mukainaka T; Tokuda H; Nishino H
Inhibitory effects of anthraquinones and bianthraquinones on Epstein-Barr virus activation.
Cancer letters 2001;170(1):15-8.
2001: Itoigawa M; Ito C; Tan H T; Kuchide M; Tokuda H; Nishino H; Furukawa H
Cancer chemopreventive agents, 4-phenylcoumarins from Calophyllum inophyllum.
Cancer letters 2001;169(1):15-9.
2001: Colombo D; Compostella F; Ronchetti F; Scala A; Tokuda H; Nishino H
Diesters of glycosylglycerols active in cancer chemoprevention.
European journal of medicinal chemistry 2001;36(7-8):691-5.
2001: Iwamoto M; Ohtsu H; Tokuda H; Nishino H; Matsunaga S; Tanaka R
Anti-tumor promoting diterpenes from the stem bark of Thuja standishii (Cupressaceae).
Bioorganic & medicinal chemistry 2001;9(7):1911-21.
2001: Uesato S; Kitagawa Y; Kaijima T; Tokuda H; Okuda M; Mou X Y; Mukainaka T; Nishino H
Inhibitory effects of 6-O-acylated L-ascorbic acids possessing a straight- or branched-acyl chain on Epstein-Barr virus activation.
Cancer letters 2001;166(2):143-6.
2001: Ito C; Itoigawa M; Mishina Y; Tomiyasu H; Litaudon M; Cosson J P; Mukainaka T; Tokuda H; Nishino H; Furukawa H
Cancer chemopreventive agents. New depsidones from Garcinia plants.
Journal of natural products 2001;64(2):147-50.
2001: Ohtsu H; Tanak R; In Y; Matsunaga S; Tokuda H; Nishino H
Abietane diterpenoids from the cones of Larix kaempferi and their inhibitory effects on Epstein-Barr virus activation.
Planta medica 2001;67(1):55-60.
2001: Iwase Y; Takemura Y; Ju-ichi M; Yano M; Ito C; Furukawa H; Mukainaka T; Kuchide M; Tokuda H; Nishino H
Cancer chemopreventive activity of 3,5,6,7,8,3',4'-heptamethoxyflavone from the peel of citrus plants.
Cancer letters 2001;163(1):7-9.
2000: Colombo D; Compostella F; Ronchetti F; Scala A; Toma L; Tokuda H; Nishino H
Glycoglycerolipid analogues active as anti-tumor-promoters: the influence of the anomeric configuration.
European journal of medicinal chemistry 2000;35(12):1109-13.
2000: Kapadia G J; Azuine M A; Takayasu J; Konoshima T; Takasaki M; Nishino H; Tokuda H
Inhibition of epstein-barr virus early antigen activation promoted by 12-O-tetradecanoylphorbol-13-acetate by the non-steroidal anti-inflammatory drugs.
Cancer letters 2000;161(2):221-9.
2000: Colombo D; Compostella F; Ronchetti F; Scala A; Toma L; Kuchide M; Tokuda H; Nishino H
Anti-tumor-promoting effects of glycoglycerolipid analogues on two-stage mouse skin carcinogenesis.
Cancer letters 2000;161(2):201-5.
2000: Tanaka R; Ohtsu H; Iwamoto M; Minami T; Tokuda H; Nishino H; Matsunaga S; Yoshitake A
Cancer chemopreventive agents, labdane diterpenoids from the stem bark of Thuja standishii (Gord.) Carr.
Cancer letters 2000;161(2):165-70.
2000: Tanaka R; Kinouchi Y; Tokuda H; Nishino H; Matsunaga S
Bioactive triterpenoids from the stem bark of Picea glehni.
Planta medica 2000;66(7):630-4.
2000: Ito C; Itoigawa M; Otsuka T; Tokuda H; Nishino H; Furukawa H
Constituents of Boronia pinnata.
Journal of natural products 2000;63(10):1344-8.
2000: Ishida J; Kozuka M; Wang H; Konoshima T; Tokuda H; Okuda M; Yang Mou X; Nishino H; Sakurai N; Lee K H; Nagai M
Antitumor-promoting effects of cyclic diarylheptanoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 2000;159(2):135-40.
2000: Ito H; Koreishi M; Tokuda H; Nishino H; Yoshida T
Cypellocarpins A-C, phenol glycosides esterified with oleuropeic acid, from Eucalyptus cypellocarpa.
Journal of natural products 2000;63(9):1253-7.
2000: Ito C; Itoigawa M; Katsuno S; Omura M; Tokuda H; Nishino H; Furukawa H
Chemical constituents of Clausena excavata: isolation and structure elucidation of novel furanone-coumarins with inhibitory effects for tumor-promotion.
Journal of natural products 2000;63(9):1218-24.
2000: Ito H; Muranaka T; Mori K; Jin Z X; Tokuda H; Nishino H; Yoshida T
Ichthyotoxic phloroglucinol derivatives from Dryopteris fragrans and their anti-tumor promoting activity.
Chemical & pharmaceutical bulletin 2000;48(8):1190-5.
2000: Uesato S; Kitagawa Y; Hara Y; Tokuda H; Okuda M; Mou X Y; Mukainaka T; Nishino H
Antitumor promoting activities of 3-O-acyl-(-)epigallocatechins.
Bioorganic & medicinal chemistry letters 2000;10(15):1673-5.
2000: González A G; Tincusi B M; Bazzocchi I L; Tokuda H; Nishino H; Konoshima T; Jiménez I A; Ravelo A G
Anti-tumor promoting effects of sesquiterpenes from Maytenus cuzcoina (Celastraceae).
Bioorganic & medicinal chemistry 2000;8(7):1773-8.
2000: Kinouchi Y; Ohtsu H; Tokuda H; Nishino H; Matsunaga S; Tanaka R
Potential antitumor-promoting diterpenoids from the stem bark of Picea glehni.
Journal of natural products 2000;63(6):817-20.
2000: Tamura S; Fukamiya N; Mou X Y; Mukainaka T; Tokuda H; Nishino H; Tagahara K; Koike K; Lee K H; Okano M
Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol.
Chemical & pharmaceutical bulletin 2000;48(6):876-8.
2000: Iwase Y; Takemura Y; Ju-ichi M; Ito C; Furukawa H; Kawaii S; Yano M; Mou X Y; Takayasu J; Tokuda H; Nishino H
Inhibitory effect of flavonoids from citrus plants on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
Cancer letters 2000;154(1):101-5.
2000: Ito C; Itoigawa M; Tan H T; Tokuda H; Yang Mou X; Mukainaka T; Ishikawa T; Nishino H; Furukawa H
Anti-tumor-promoting effects of isoflavonoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 2000;152(2):187-92.
2000: Tanaka R; Aoki H; Mizota T; Wada S; Matsunaga S; Tokuda H; Nishino H
Three new lanostane-type triterpene lactones from the stem bark of Abies mariesii.
Planta medica 2000;66(2):163-8.
2000: Ito C; Katsuno S; Itoigawa M; Ruangrungsi N; Mukainaka T; Okuda M; Kitagawa Y; Tokuda H; Nishino H; Furukawa H
New carbazole alkaloids from Clausena anisata with antitumor promoting activity.
Journal of natural products 2000;63(1):125-8.
2000: Tanaka R; Kasubuchi K; Kita S; Tokuda H; Nishino H; Matsunaga S
Bioactive steroids from the whole herb of Euphorbia chamaesyce.
Journal of natural products 2000;63(1):99-103.
2000: Nishino H; Tokuda H; Murakoshi M; Satomi Y; Masuda M; Onozuka M; Yamaguchi S; Takayasu J; Tsuruta J; Okuda M; Khachik F; Narisawa T; Takasuka N; Yano M
Cancer prevention by natural carotenoids.
BioFactors (Oxford, England) 2000;13(1-4):89-94.
1999: Konoshima T; Takasaki M; Ichiishi E; Murakami T; Tokuda H; Nishino H; Duc N M; Kasai R; Yamasaki K
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
Cancer letters 1999;147(1-2):11-6.
1999: Ito C; Itoigawa M; Miyamoto Y; Rao K S; Takayasu J; Okuda Y; Mukainaka T; Tokuda H; Nishino H; Furukawa H
A new biflavonoid from Calophyllum panciflorum with antitumor-promoting activity.
Journal of natural products 1999;62(12):1668-71.
1999: Konoshima T; Takasaki M; Tokuda H
Anti-carcinogenic activity of the roots of Panax notoginseng. II.
Biological & pharmaceutical bulletin 1999;22(10):1150-2.
1999: Nishino H; Murakoshi M; Masuda M; Tokuda H; Satomi Y; Onozuka M; Yamaguchi S; Bu P; Tsuruta A; Nosaka K; Baba M; Takasuka N
Suppression of lung and liver carcinogenesis in mice by oral administration of myo-inositol.
Anticancer research 1999;19(5A):3663-4.
1999: Colombo D; Compostella F; Ronchetti F; Scala A; Toma L; Tokuda H; Nishino H
Chemoenzymatic synthesis and antitumor promoting activity of 6'- and 3-esters of 2-O-beta-D-glucosylglycerol.
Bioorganic & medicinal chemistry 1999;7(9):1867-71.
1999: Ito H; Miyake M; Nishitani E; Mori K; Hatano T; Okuda T; Konoshima T; Takasaki M; Kozuka M; Mukainaka T; Tokuda H; Nishino H; Yoshida T
Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima.
Cancer letters 1999;143(1):5-13.
1999: Colombo D; Compostella F; Ronchetti F; Scala A; Toma L; Mukainaka T; Nagatsu A; Konoshima T; Tokuda H; Nishino H
Inhibitory effects of monoacylated 2-O-beta-galactosylglycerols on Epstein-Barr virus activation: the significant role of the hexanoyl chain.
Cancer letters 1999;143(1):1-4.
1999: Takasaki M; Tokuda H; Nishino H; Konoshima T
Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens.
Journal of natural products 1999;62(7):972-5.
1999: Ito C; Itoigawa M; Furukawa H; Ichiishi E; Mukainaka T; Okuda M; Ogata M; Tokuda H; Nishino H
Anti-tumor-promoting effects of phenylpropanoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 1999;142(1):49-54.
1999: Takasaki M; Konoshima T; Tokuda H; Masuda K; Arai Y; Shiojima K; Ageta H
Anti-carcinogenic activity of Taraxacum plant. II.
Biological & pharmaceutical bulletin 1999;22(6):606-10.
1999: Takasaki M; Konoshima T; Tokuda H; Masuda K; Arai Y; Shiojima K; Ageta H
Anti-carcinogenic activity of Taraxacum plant. I.
Biological & pharmaceutical bulletin 1999;22(6):602-5.
1999: Iwase Y; Takemura Y; Ju-ichi M; Kawaii S; Yano M; Okuda Y; Mukainaka T; Tsuruta A; Okuda M; Takayasu J; Tokuda H; Nishino H
Inhibitory effect of Epstein-Barr virus activation by Citrus fruits, a cancer chemopreventor.
Cancer letters 1999;139(2):227-36.
1999: Ito C; Itoigawa M; Furukawa H; Tokuda H; Okuda Y; Mukainaka T; Okuda M; Nishino H
Anti-tumor-promoting effects of 8-substituted 7-methoxycoumarins on Epstein-Barr virus activation assay.
Cancer letters 1999;138(1-2):87-92.
1998: Ito C; Itoigawa M; Furukawa H; Rao K S; Enjo F; Bu P; Takayasu J; Tokuda H; Nishino H
Xanthones as inhibitors of Epstein-Barr virus activation.
Cancer letters 1998;132(1-2):113-7.
1998: Konishi T; Takasaki M; Tokuda H; Kiyosawa S; Konoshima T
Anti-tumor-promoting activity of diterpenes from Excoecaria agallocha.
Biological & pharmaceutical bulletin 1998;21(9):993-6.
1998: Konoshima T; Takasaki M; Tokuda H; Nishino H; Duc N M; Kasai R; Yamasaki K
Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I).
Biological & pharmaceutical bulletin 1998;21(8):834-8.
1998: Kapadia G J; Tokuda H; Sridhar R; Balasubramanian V; Takayasu J; Bu P; Enjo F; Takasaki M; Konoshima T; Nishino H
Cancer chemopreventive activity of synthetic colorants used in foods, pharmaceuticals and cosmetic preparations.
Cancer letters 1998;129(1):87-95.
1998: Fujiwara A; Mori T; Iida A; Ueda S; Hano Y; Nomura T; Tokuda H; Nishino H
Antitumor-promoting naphthoquinones from Catalpa ovata.
Journal of natural products 1998;61(5):629-32.
1998: Colombo D; Scala A; Taino I M; Toma L; Ronchetti F; Tokuda H; Nishino H; Nagatsu A; Sakakibara J
Inhibitory effects of fatty acid monoesters of 2-O-beta-D-glucosylglycerol on Epstein-Barr virus activation.
Cancer letters 1998;123(1):83-6.
1997: Konoshima T; Takasaki M; Kozuka M; Tokuda H; Nishino H; Matsuda E; Nagai M
Anti-tumor promoting activities of isoflavonoids from Wistaria brachybotrys.
Biological & pharmaceutical bulletin 1997;20(8):865-8.
1997: Takasaki M; Konoshima T; Yasuda I; Hamano T; Tokuda H
Inhibitory effects of shouseiryu-to on two-stage carcinogenesis. II. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum.
Biological & pharmaceutical bulletin 1997;20(7):776-80.
1997: Koyama J; Tagahara K; Osakai T; Tsujino Y; Tsurumi S; Nishino H; Tokuda H
Inhibitory effects on Epstein-Barr virus activation of anthraquinones: correlation with redox potentials.
Cancer letters 1997;115(2):179-83.
1997: Kapadia G J; Balasubramanian V; Tokuda H; Iwashima A; Nishino H
Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation by natural colorants.
Cancer letters 1997;115(2):173-8.
1997: Rahman S; Fukamiya N; Ohno N; Tokuda H; Nishino H; Tagahara K; Lee K H; Okano M
Inhibitory effects of quassinoid derivatives on Epstein-Barr virus early antigen activation.
Chemical & pharmaceutical bulletin 1997;45(4):675-7.
1997: Kubota K; Fukamiya N; Tokuda H; Nishino H; Tagahara K; Lee K H; Okano M
Quassinoids as inhibitors of Epstein-Barr virus early antigen activation.
Cancer letters 1997;113(1-2):165-8.
1997: Kapadia G J; Balasubramanian V; Tokuda H; Konoshima T; Takasaki M; Koyama J; Tagahaya K; Nishino H
Anti-tumor promoting effects of naphthoquinone derivatives on short term Epstein-Barr early antigen activation assay and in mouse skin carcinogenesis.
Cancer letters 1997;113(1-2):47-53.
1996: Kapadia G J; Tokuda H; Konoshima T; Takasaki M; Takayasu J; Nishino H
Anti-tumor promoting activity of Dryopteris phlorophenone derivatives.
Cancer letters 1996;105(2):161-5.
1996: Konoshima T; Takasaki M; Tokuda H; Masuda K; Arai Y; Shiojima K; Ageta H
Anti-tumor-promoting activities of triterpenoids from ferns. I.
Biological & pharmaceutical bulletin 1996;19(7):962-5.
1996: Shirahashi H; Morimoto T; Nagatsu A; Murakami N; Tatta K; Sakakibara J; Tokuda H; Nishino H
Antitumor-promoting activities of various synthetic 1-O-acyl-3-O-(6'-O-acyl-beta-D-galactopyranosyl)-sn-glycerols related to natural product from freshwater cyanobacterium Anabaena flos-aquae f. flos-aquae.
Chemical & pharmaceutical bulletin 1996;44(7):1404-6.
1996: Tokuda H; Nishino H; Shirahashi H; Murakami N; Nagatsu A; Sakakibara J
Inhibition of 12-O-tetradecanoylphorbol-13-acetate promoted mouse skin papilloma by digalactosyl diacylglycerols from the fresh water cyanobacterium Phormidium tenue.
Cancer letters 1996;104(1):91-5.
1996: Kapadia G J; Sharma S C; Tokuda H; Nishino H; Ueda S
Inhibitory effect of iridoids on Epstein-Barr virus activation by a short-term in vitro assay for anti-tumor promoters.
Cancer letters 1996;102(1-2):223-6.
1996: Kapadia G J; Tokuda H; Konoshima T; Nishino H
Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract.
Cancer letters 1996;100(1-2):211-4.
1995: Morimoto T; Nagatsu A; Murakami N; Sakakibara J; Tokuda H; Nishino H; Iwashima A
Anti-tumour-promoting glyceroglycolipids from the green alga, Chlorella vulgaris.
Phytochemistry 1995;40(5):1433-7.
1995: Okano M; Fukamiya N; Tagahara K; Tokuda H; Iwashima A; Nishino H; Lee K H
Inhibitory effects of quassinoids on Epstein-Barr virus activation.
Cancer letters 1995;94(2):139-46.
1995: Takasaki M; Konoshima T; Kozuka M; Tokuda H
Anti-tumor-promoting activities of euglobals from Eucalyptus plants.
Biological & pharmaceutical bulletin 1995;18(3):435-8.
1995: Konoshima T; Takasaki M; Kozuka M; Nagao T; Okabe H; Irino N; Nakasumi T; Tokuda H; Nishino H
Inhibitory effects of cucurbitane triterpenoids on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumor. II.
Biological & pharmaceutical bulletin 1995;18(2):284-7.
1994: Konoshima T; Takasaki M; Tatsumoto T; Kozuka M; Kasai R; Tanaka O; Nie R L; Tokuda H; Nishino H; Iwashima A
Inhibitory effects of cucurbitane triterpenoids on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
Biological & pharmaceutical bulletin 1994;17(5):668-71.
1993: Shirahashi H; Murakami N; Watanabe M; Nagatsu A; Sakakibara J; Tokuda H; Nishino H; Iwashima A
Isolation and identification of anti-tumor-promoting principles from the fresh-water cyanobacterium Phormidium tenue.
Chemical & pharmaceutical bulletin 1993;41(9):1664-6.
1993: Konoshima T; Terada H; Kokumai M; Kozuka M; Tokuda H; Estes J R; Li L; Wang H K; Lee K H
Studies on inhibitors of skin tumor promotion, XII. Rotenoids from Amorpha fruticosa.
Journal of natural products 1993;56(6):843-8.
1992: Murakoshi M; Nishino H; Satomi Y; Takayasu J; Hasegawa T; Tokuda H; Iwashima A; Okuzumi J; Okabe H; Kitano H
Potent preventive action of alpha-carotene against carcinogenesis: spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha-carotene than by beta-carotene.
Cancer research 1992;52(23):6583-7.
1992: Murakoshi M; Nishino H; Tokuda H; Iwashima A; Okuzumi J; Kitano H; Iwasaki R
Inhibition by squalene of the tumor-promoting activity of 12-O-tetradecanoylphorbol-13-acetate in mouse-skin carcinogenesis.
International journal of cancer. Journal international du cancer 1992;52(6):950-2.
1992: Konoshima T; Kokumai M; Kozuka M; Tokuda H; Nishino H; Iwashima A
Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys.
Journal of natural products 1992;55(12):1776-8.
1992: Nishino H; Tsushima M; Matsuno T; Tanaka Y; Okuzumi J; Murakoshi M; Satomi Y; Takayasu J; Tokuda H; Nishino A
Anti-neoplastic effect of halocynthiaxanthin, a metabolite of fucoxanthin.
Anti-cancer drugs 1992;3(5):493-7.
1992: Konoshima T; Kokumai M; Kozuka M; Iinuma M; Mizuno M; Tanaka T; Tokuda H; Nishino H; Iwashima A
Studies on inhibitors of skin tumor promotion. XI. Inhibitory effects of flavonoids from Scutellaria baicalensis on Epstein-Barr virus activation and their anti-tumor-promoting activities.
Chemical & pharmaceutical bulletin 1992;40(2):531-3.
1991: Okuyama T; Takata M; Takayasu J; Hasegawa T; Tokuda H; Nishino A; Nishino H; Iwashima A
Anti-tumor-promotion by principles obtained from Angelica keiskei.
Planta medica 1991;57(3):242-6.
1991: Shibata S; Inoue H; Iwata S; Ma R D; Yu L J; Ueyama H; Takayasu J; Hasegawa T; Tokuda H; Nishino A
Inhibitory effects of licochalcone A isolated from Glycyrrhiza inflata root on inflammatory ear edema and tumour promotion in mice.
Planta medica 1991;57(3):221-4.
1991: Konoshima T; Kozuka M; Tokuda H; Nishino H; Iwashima A; Haruna M; Ito K; Tanabe M
Studies on inhibitors of skin tumor promotion, IX. Neolignans from Magnolia officinalis.
Journal of natural products 1991;54(3):816-22.
1990: Takasaki M; Konoshima T; Fujitani K; Yoshida S; Nishimura H; Tokuda H; Nishino H; Iwashima A; Kozuka M
Inhibitors of skin-tumor promotion. VIII. Inhibitory effects of euglobals and their related compounds on Epstein-Barr virus activation. (1).
Chemical & pharmaceutical bulletin 1990;38(10):2737-9.
1990: Takayasu J; Tanaka R; Matsunaga S; Ueyama H; Tokuda H; Hasegawa T; Nishino A; Nishino H; Iwashima A
Anti-tumor-promoting activity of derivatives of abieslactone, a natural triterpenoid isolated from several Abies genus.
Cancer letters 1990;53(2-3):141-4.
1990: Nishino H; Okuyama T; Takata M; Shibata S; Tokuda H; Takayasu J; Hasegawa T; Nishino A; Ueyama H; Iwashima A
Studies on the anti-tumor-promoting activity of naturally occurring substances. IV. Pd-II [(+)anomalin, (+)praeruptorin B], a seselin-type coumarin, inhibits the promotion of skin tumor formation by 12-O-tetradecanoylphorbol-13-acetate in 7,12-dimethylbenz[a]anthracene-initiated mice.
Carcinogenesis 1990;11(9):1557-61.
1990: Takasaki M; Konoshima T; Shingu T; Tokuda H; Nishino H; Iwashima A; Kozuka M
Structures of euglobal-G1, -G2, and -G3 from Eucalyptus grandis, three new inhibitors of Epstein-Barr virus activation.
Chemical & pharmaceutical bulletin 1990;38(5):1444-6.
1989: Konoshima T; Kozuka M; Koyama J; Okatani T; Tagahara K; Tokuda H
Studies on inhibitors of skin tumor promotion, VI. Inhibitory effects of quinones on Epstein-Barr virus activation.
Journal of natural products 1989;52(5):987-95.
1988: Konoshima T; Okamoto E; Kozuka M; Nishino H; Tokuda H; Tanabe M
Studies on inhibitors of skin tumor promotion, III. Inhibitory effects of isoflavonoids from Wisteria brachybotrys on Epstein-Barr virus activation.
Journal of natural products 1988;51(6):1266-70.
1987: Konoshima T; Takasaki M; Kozuka M; Tokuda H
Studies on inhibitors of skin-tumor promotion, I. Inhibitory effects of triterpenes from Euptelea polyandra on Epstein-Barr virus activation.
Journal of natural products 1987;50(6):1167-70.

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