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Haruhiko Tokuda

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Akira Kondo; Kenji Kato; Gen Kuroyanagi; Rie Matsushima-Nishiwaki; Jun Mizutani; Takanobu Otsuka; Haruhiko Tokuda; Osamu Kozawa
AMP-activated protein kinase regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.
Nguyen The Cuong; Tomoaki Doi; Akira Kondo; Osamu Kozawa; Gen Kuroyanagi; Rie Matsushima-Nishiwaki; Jun Mizutani; Takanobu Otsuka; Haruhiko Tokuda; Ikuo Wada; Shigeru Akamatsu; Shinji Ogura
Thrombopoietin amplifies ADP-induced HSP27 phosphorylation in human platelets: importance of pre-treatment.
Akira Kondo; Osamu Kozawa; Gen Kuroyanagi; Rie Matsushima-Nishiwaki; Jun Mizutani; Kenji Kato; Haruhiko Tokuda; Takanobu Otsuka
Rho-kinase negatively regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.

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2013: Akira Kondo; Kenji Kato; Gen Kuroyanagi; Rie Matsushima-Nishiwaki; Jun Mizutani; Takanobu Otsuka; Haruhiko Tokuda; Osamu Kozawa
AMP-activated protein kinase regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.
International journal of molecular medicine 2013;31(6):1457-62.
2013: Nguyen The Cuong; Tomoaki Doi; Akira Kondo; Osamu Kozawa; Gen Kuroyanagi; Rie Matsushima-Nishiwaki; Jun Mizutani; Takanobu Otsuka; Haruhiko Tokuda; Ikuo Wada; Shigeru Akamatsu; Shinji Ogura
Thrombopoietin amplifies ADP-induced HSP27 phosphorylation in human platelets: importance of pre-treatment.
International journal of molecular medicine 2013;31(6):1291-7.
2013: Akira Kondo; Osamu Kozawa; Gen Kuroyanagi; Rie Matsushima-Nishiwaki; Jun Mizutani; Kenji Kato; Haruhiko Tokuda; Takanobu Otsuka
Rho-kinase negatively regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.
Biochimie 2013;95(4):719-24.
2012: Akira Kondo; Osamu Kozawa; Gen Kuroyanagi; Rie Matsushima-Nishiwaki; Jun Mizutani; Hideo Natsume; Takanobu Otsuka; Yoshiki Ito; Kenji Kato; Haruhiko Tokuda
AMP-activated protein kinase inhibitor decreases prostaglandin F2α-stimulated interleukin-6 synthesis through p38 MAP kinase in osteoblasts.
International journal of molecular medicine 2012;30(6):1487-92.
2012: Tomoaki Doi; Hiroki Iida; Yuko Iida; Yasunari Kageyama; Akira Kondo; Osamu Kozawa; Rie Matsushima-Nishiwaki; Shigeru Akamatsu; Nguyen The Cuong; Takanobu Otsuka; Haruhiko Tokuda; Shinji Ogura
Effect of antithrombin III on glycoprotein Ib/IX/V activation in human platelets: suppression of thromboxane A2 generation.
Prostaglandins, leukotrienes, and essential fatty acids 2012;87(2-3):57-62.
2012: Akira Kondo; Osamu Kozawa; Rie Matsushima-Nishiwaki; Jun Mizutani; Haruhiko Tokuda; Takanobu Otsuka
Wnt3a upregulates prostaglandin F2α-stimulated vascular endothelial growth factor synthesis in osteoblasts.
Molecular medicine reports 2012;6(2):421-5.
2012: Kenji Kato; Akira Kondo; Osamu Kozawa; Rie Matsushima-Nishiwaki; Hideo Natsume; Yoshiki Ito; Haruhiko Tokuda; Takanobu Otsuka
AMPK limits IL-1-stimulated IL-6 synthesis in osteoblasts: involvement of IκB/NF-κB pathway.
Cellular signalling 2012;24(8):1706-12.
2012: Jun Mizutani; Hideo Natsume; Haruhiko Tokuda; Kenji Kato; Akira Kondo; Osamu Kozawa; Rie Matsushima-Nishiwaki; Takanobu Otsuka
Involvement of AMP-activated protein kinase in TGF-β-stimulated VEGF synthesis in osteoblasts.
International journal of molecular medicine 2012;29(4):550-6.
2011: Kenji Kato; Osamu Kozawa; Rie Matsushima-Nishiwaki; Jun Mizutani; Hideo Natsume; Seiji Adachi; Haruhiko Tokuda; Takanobu Otsuka
Role of HSP27 in tumor necrosis factor-α-stimulated interleukin-6 synthesis in osteoblasts.
International journal of molecular medicine 2011;28(5):887-93.
2011: Kenji Kato; Osamu Kozawa; Rie Matsushima-Nishiwaki; Hideo Natsume; Takanobu Otsuka; Haruhiko Tokuda
Rho-kinase regulates thrombin-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts.
International journal of molecular medicine 2011;28(4):653-8.
2011: Hideo Natsume; Takanobu Otsuka; Haruhiko Tokuda; Kengo Yamakawa; Kenji Kato; Rie Matsushima-Nishiwaki; Osamu Kozawa
Wnt3a upregulates transforming growth factor-β-stimulated VEGF synthesis in osteoblasts.
Cell biochemistry and function 2011;29(5):371-7.
2011: Kenji Kato; Seiji Adachi; Rie Matsushima-Nishiwaki; Chiho Minamitani; Hideo Natsume; Yasuo Katagiri; Yoshinobu Hirose; Jun Mizutani; Haruhiko Tokuda; Osamu Kozawa; Takanobu Otsuka
Regulation by heat shock protein 27 of osteocalcin synthesis in osteoblasts.
Endocrinology 2011;152(5):1872-82.
2011: Yukiko Enomoto; Seiji Adachi; Tomoaki Doi; Hideo Natsume; Kenji Kato; Rie Matsushima-Nishiwaki; Shigeru Akamatsu; Haruhiko Tokuda; Shinichi Yoshimura; Takanobu Otsuka; Shinji Ogura; Osamu Kozawa; Toru Iwama
cAMP regulates ADP-induced HSP27 phosphorylation in human platelets.
International journal of molecular medicine 2011;27(5):695-700.
2011: Kenji Kato; Takanobu Otsuka; Seiji Adachi; Rie Matsushima-Nishiwaki; Hideo Natsume; Osamu Kozawa; Haruhiko Tokuda
(-)-Epigallocatechin gallate inhibits thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.
Molecular medicine reports 2011;4(2):297-300.
2011: Kenji Kato; Haruhiko Tokuda; Seiji Adachi; Rie Matsushima-Nishiwaki; Junichi Yamauchi; Hideo Natsume; Chiho Minamitani; Jun Mizutani; Takanobu Otsuka; Osamu Kozawa
Role of heat shock protein 27 in transforming growth factor-β-stimulated vascular endothelial growth factor release in osteoblasts.
International journal of molecular medicine 2011;27(3):423-8.
2011: Hideo Natsume; Haruhiko Tokuda; Seiji Adachi; Rie Matsushima-Nishiwaki; Kenji Kato; Chiho Minamitani; Takanobu Otsuka; Osamu Kozawa
Wnt3a regulates tumor necrosis factor-α-stimulated interleukin-6 release in osteoblasts.
Molecular and cellular endocrinology 2011;331(1):66-72.
2010: Kenji Kato; Haruhiko Tokuda; Seiji Adachi; Rie Matsushima-Nishiwaki; Hideo Natsume; Kengo Yamakawa; Yumi Gu; Takanobu Otsuka; Osamu Kozawa
AMP-activated protein kinase positively regulates FGF-2-stimulated VEGF synthesis in osteoblasts.
Biochemical and biophysical research communications 2010;400(1):123-7.
2010: Tomoaki Doi; Seiji Adachi; Rie Matsushima-Nishiwaki; Hisaaki Kato; Yukiko Enomoto; Hideo Natsume; Kenji Kato; Jun Mizutani; Takanobu Otsuka; Haruhiko Tokuda; Shigeru Akamatsu; Toru Iwama; Osamu Kozawa; Shinji Ogura
Antithrombin III reduces collagen-stimulated granule secretion of PDGF-AB and the release of soluble CD40 ligand from human platelets.
International journal of molecular medicine 2010;26(3):387-92.
2010: Hisaaki Kato; Seiji Adachi; Tomoaki Doi; Rie Matsushima-Nishiwaki; Chiho Minamitani; Shigeru Akamatsu; Yukiko Enomoto; Haruhiko Tokuda; Takanobu Otsuka; Toru Iwama; Osamu Kozawa; Shinji Ogura
Mechanism of collagen-induced release of 5-HT, PDGF-AB and sCD40L from human platelets: role of HSP27 phosphorylation via p44/p42 MAPK.
Thrombosis research 2010;126(1):39-43.
2010: Hideo Natsume; Haruhiko Tokuda; Jun Mizutani; Seiji Adachi; Rie Matsushima-Nishiwaki; Chiho Minamitani; Kenji Kato; Osamu Kozawa; Takanobu Otsuka
Synergistic effect of vasoactive intestinal peptides on TNF-alpha-induced IL-6 synthesis in osteoblasts: amplification of p44/p42 MAP kinase activation.
International journal of molecular medicine 2010;25(5):813-7.
2010: Hideo Natsume; Haruhiko Tokuda; Seiji Adachi; Shinji Takai; Rie Matsushima-Nishiwaki; Kenji Kato; Chiho Minamitani; Shunpei Niida; Jun Mizutani; Osamu Kozawa; Takanobu Otsuka
Rho-kinase limits FGF-2-stimulated VEGF release in osteoblasts.
Bone 2010;46(4):1068-74.
2010: Yukiko Enomoto; Seiji Adachi; Rie Matsushima-Nishiwaki; Tomoaki Doi; Masayuki Niwa; Shigeru Akamatsu; Haruhiko Tokuda; Shinji Ogura; Shinichi Yoshimura; Toru Iwama; Osamu Kozawa
Thromboxane A(2) promotes soluble CD40 ligand release from human platelets.
Atherosclerosis 2010;209(2):415-21.
2010: Chiho Minamitani; Haruhiko Tokuda; Seiji Adachi; Rie Matsushima-Nishiwaki; Junichi Yamauchi; Kenji Kato; Hideo Natsume; Jun Mizutani; Osamu Kozawa; Takanobu Otsuka
p70 S6 kinase limits tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblast-like cells.
Molecular and cellular endocrinology 2010;315(1-2):195-200.
2010: Haruhiko Tokuda; Seiji Adachi; Rie Matsushima-Nishiwaki; Yoshiteru Hanai; Shinji Takai; Atsushi Harada; Osamu Kozawa
Inhibition by minodronate of basic fibroblast growth factor-stimulated vascular endothelial growth factor synthesis in osteoblast-like cells.
Molecular medicine reports 2010;3(1):167-71.
2010: Shinji Takai; Haruhiko Tokuda; Rie Matsushima-Nishiwaki; Masanao Saio; Tsuyoshi Takami; Osamu Kozawa
TGF-beta superfamily enhances the antigen-induced IFN-gamma production by effector/memory CD8+ T cells.
International journal of molecular medicine 2010;25(1):105-11.
2010: Haruhiko Tokuda; A Harada; S Adachi; Rie Matsushima-Nishiwaki; H Natsume; C Minamitani; J Mizutani; T Otsuka; Osamu Kozawa
Raloxifene enhances spontaneous microaggregation of platelets through upregulation of p44/p42 MAP kinase: a case report.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2010;21(1):189-93.
2009: Seiji Adachi; Haruhiko Tokuda; Rie Matsushima-Nishiwaki; Kenji Kato; Hideo Natsume; Chiho Minamitani; Jun Mizutani; Takanobu Otsuka; Osamu Kozawa
Involvement of Rho-kinase in prostaglandin E(1)-stimulated VEGF synthesis through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblast-like MC3T3-E1 cells.
Prostaglandins & other lipid mediators 2009;90(1-2):1-6.
2009: Hideo Natsume; Jun Mizutani; Seiji Adachi; Rie Matsushima-Nishiwaki; Chiho Minamitani; Haruhiko Tokuda; Osamu Kozawa; Takanobu Otsuka
Involvement of Rho-kinase in TGF-β-stimulated heat shock protein 27 induction in osteoblasts.
Molecular medicine reports 2009;2(5):687-91.
2009: Tomoaki Doi; Seiji Adachi; Shinji Takai; Rie Matsushima-Nishiwaki; Hisaaki Kato; Yukiko Enomoto; Chiho Minamitani; Takanobu Otsuka; Haruhiko Tokuda; Shigeru Akamatsu; Toru Iwama; Osamu Kozawa; Shinji Ogura
Antithrombin III suppresses ADP-induced platelet granule secretion: inhibition of HSP27 phosphorylation.
Archives of biochemistry and biophysics 2009;489(1-2):62-7.
2009: Yoshiteru Hanai; Seiji Adachi; Ichiro Yasuda; Shinji Takai; Rie Matsushima-Nishiwaki; Hisaaki Kato; Yukiko Enomoto; Shigeru Akamatsu; Seiko Sakakibara; Shinji Ogura; Toru Iwama; Osamu Kozawa; Haruhiko Tokuda
Collagen-induced p38 MAP kinase activation is a biomarker of platelet hyper-aggregation in patients with diabetes mellitus.
Life sciences 2009;85(9-10):386-94.
2009: Yukiko Enomoto; Seiji Adachi; Rie Matsushima-Nishiwaki; Masayuki Niwa; Haruhiko Tokuda; Shigeru Akamatsu; Tomoaki Doi; Hisaaki Kato; Shinichi Yoshimura; Shinji Ogura; Toru Iwama; Osamu Kozawa
alphaB-crystallin extracellularly suppresses ADP-induced granule secretion from human platelets.
FEBS letters 2009;583(15):2464-8.
2009: Hideo Natsume; Seiji Adachi; Shinji Takai; Haruhiko Tokuda; Rie Matsushima-Nishiwaki; Chiho Minamitani; Junichi Yamauchi; Kanefusa Kato; Jun Mizutani; Osamu Kozawa; Takanobu Otsuka
(-)-Epigallocatechin gallate attenuates the induction of HSP27 stimulated by sphingosine 1-phosphate via suppression of phosphatidylinositol 3-kinase/Akt pathway in osteoblasts.
International journal of molecular medicine 2009;24(2):197-203.
2009: Chiho Minamitani; Takanobu Otsuka; Shinji Takai; Rie Matsushima-Nishiwaki; Seiji Adachi; Yoshiteru Hanai; Jun Mizutani; Haruhiko Tokuda; Osamu Kozawa
Involvement of Rho-kinase in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts.
International journal of molecular medicine 2009;24(1):77-82.
2009: Haruhiko Tokuda; T Hosoi; K Hayasaka; K Okamura; N Yoshimi; Osamu Kozawa
Overexpression of protein kinase C-delta plays a crucial role in interleukin-6-producing pheochromocytoma presenting with acute inflammatory syndrome: a case report.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2009;41(4):333-8.
2009: Junichi Yamauchi; Shinji Takai; Rie Matsushima-Nishiwaki; Seiji Adachi; Chiho Minamitani; Hideo Natsume; Jun Mizutani; Takanobu Otsuka; Jun Takeda; Atsushi Harada; Osamu Kozawa; Haruhiko Tokuda
Tacrolimus but not cyclosporine A enhances FGF-2-induced VEGF release in osteoblasts.
International journal of molecular medicine 2009;23(2):267-72.
2008: Chiho Minamitani; Takanobu Otsuka; Shinji Takai; Rie Matsushima-Nishiwaki; Seiji Adachi; Yoshiteru Hanai; Jun Mizutani; Haruhiko Tokuda; Osamu Kozawa
Involvement of Rho-kinase in prostaglandin F2alpha-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts.
Molecular and cellular endocrinology 2008;291(1-2):27-32.
2008: Haruhiko Tokuda; Shinji Takai; Rie Matsushima-Nishiwaki; Yoshiteru Hanai; Seiji Adachi; Chiho Minamitani; Jun Mizutani; Takanobu Otsuka; Osamu Kozawa
Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts.
Prostaglandins, leukotrienes, and essential fatty acids 2008;79(1-2):41-6.
2008: Hisaaki Kato; Shinji Takai; Rie Matsushima-Nishiwaki; Seiji Adachi; Chiho Minamitani; Takanobu Otsuka; Haruhiko Tokuda; Shigeru Akamatsu; Tomoaki Doi; Shinji Ogura; Osamu Kozawa
HSP27 phosphorylation is correlated with ADP-induced platelet granule secretion.
Archives of biochemistry and biophysics 2008;475(1):80-6.
2008: Kana Hayashi; Shinji Takai; Rie Matsushima-Nishiwaki; Yoshiteru Hanai; Kanefusa Kato; Haruhiko Tokuda; Osamu Kozawa
(-)-Epigallocatechin gallate reduces transforming growth factor beta-stimulated HSP27 induction through the suppression of stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Life sciences 2008;82(19-20):1012-7.
2008: Shinji Takai; Yoshiteru Hanai; Rie Matsushima-Nishiwaki; C Minamitani; T Otsuka; Haruhiko Tokuda; Osamu Kozawa
P70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C.
The Journal of endocrinology 2008;197(1):131-7.
2008: Shinji Takai; Rie Matsushima-Nishiwaki; Seiji Adachi; Hideo Natsume; Chiho Minamitani; Jun Mizutani; Takanobu Otsuka; Haruhiko Tokuda; Osamu Kozawa
(-)-Epigallocatechin gallate reduces platelet-derived growth factor-BB-stimulated interleukin-6 synthesis in osteoblasts: suppression of SAPK/JNK.
Mediators of inflammation 2008;2008():291808.
2008: Chiho Minamitani; Shinji Takai; Rie Matsushima-Nishiwaki; Yoshiteru Hanai; Takanobu Otuka; Osamu Kozawa; Haruhiko Tokuda
Raloxifene-induced acceleration of platelet aggregation.
Internal medicine (Tokyo, Japan) 2008;47(17):1523-8.
2008: Haruhiko Tokuda; Shinji Takai; Yoshiteru Hanai; Atsushi Harada; Rie Matsushima-Nishiwaki; Hisaaki Kato; Shinji Ogura; Osamu Kozawa
Potentiation by platelet-derived growth factor-BB of FGF-2-stimulated VEGF release in osteoblasts.
Journal of bone and mineral metabolism 2008;26(4):335-41.
2007: Haruhiko Tokuda; Yoshiteru Hanai; Rie Matsushima-Nishiwaki; Junichi Yamauchi; Tomoaki Doi; Atsushi Harada; Shinji Takai; Osamu Kozawa
Rho-kinase regulates endothelin-1-stimulated IL-6 synthesis via p38 MAP kinase in osteoblasts.
Biochemical and biophysical research communications 2007;362(4):799-804.
2007: Haruhiko Tokuda; Shinji Takai; Yoshiteru Hanai; Atsushi Harada; Rie Matsushima-Nishiwaki; Shigeru Akamatsu; Toshiki Ohta; Osamu Kozawa
Platelet-derived growth factor-BB amplifies PGF2alpha-stimulated VEGF synthesis in osteoblasts: function of phosphatidylinositol 3-kinase.
Prostaglandins, leukotrienes, and essential fatty acids 2007;77(3-4):187-93.
2007: Junichi Yamauchi; Shinji Takai; Rie Matsushima-Nishiwaki; Yoshiteru Hanai; Tomoaki Doi; Hisaaki Kato; Shinji Ogura; Kanefusa Kato; Haruhiko Tokuda; Osamu Kozawa
(-)-epigallocatechin gallate inhibits prostaglandin D2-stimulated HSP27 induction via suppression of the p44/p42 MAP kinase pathway in osteoblasts.
Prostaglandins, leukotrienes, and essential fatty acids 2007;77(3-4):173-9.
2007: Shinji Takai; Rie Matsushima-Nishiwaki; Haruhiko Tokuda; Eisuke Yasuda; Hidenori Toyoda; Yuji Kaneoka; Akihiro Yamaguchi; Takashi Kumada; Osamu Kozawa
Protein kinase C delta regulates the phosphorylation of heat shock protein 27 in human hepatocellular carcinoma.
Life sciences 2007;81(7):585-91.
2007: Haruhiko Tokuda; Shinji Takai; Yoshiteru Hanai; Rie Matsushima-Nishiwaki; Takayuki Hosoi; Atsushi Harada; Toshiki Ohta; Osamu Kozawa
(-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: inhibition of p44/p42 MAP kinase activation.
FEBS letters 2007;581(7):1311-6.
2007: Shinji Takai; Haruhiko Tokuda; Yoshiteru Hanai; Osamu Kozawa
Limitation by p70 S6 kinase of platelet-derived growth factor-BB-induced interleukin 6 synthesis in osteoblast-like MC3T3-E1 cells.
Metabolism: clinical and experimental 2007;56(4):476-83.
2007: Haruhiko Tokuda; Shinji Takai; Rie Matsushima-Nishiwaki; Shigeru Akamatsu; Yoshiteru Hanai; Takayuki Hosoi; Atsushi Harada; Toshiki Ohta; Osamu Kozawa
(--)-epigallocatechin gallate enhances prostaglandin F2alpha-induced VEGF synthesis via upregulating SAPK/JNK activation in osteoblasts.
Journal of cellular biochemistry 2007;100(5):1146-53.
2007: Shinji Takai; Haruhiko Tokuda; Yoshiteru Hanai; Osamu Kozawa
Activation of phosphatidylinositol 3-kinase/Akt limits FGF-2-induced VEGF release in osteoblasts.
Molecular and cellular endocrinology 2007;267(1-2):46-54.
2007: Shinji Takai; Haruhiko Tokuda; Yoshiteru Hanai; Atsushi Harada; Eisuke Yasuda; Rie Matsushima-Nishiwaki; Hisaaki Kato; Shinji Ogura; Toshiki Ohta; Osamu Kozawa
Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(3):337-46.
2006: Yoshiteru Hanai; Haruhiko Tokuda; Eisuke Yasuda; Takahiro Noda; Toshiki Ohta; Shinji Takai; Osamu Kozawa
Up-regulation by zinc of FGF-2-induced VEGF release through enhancing p44/p42 MAP kinase activation in osteoblasts.
Life sciences 2006;80(3):230-4.
2006: Yoshiteru Hanai; Haruhiko Tokuda; Toshiki Ohta; Rie Matsushima-Nishiwaki; Shinji Takai; Osamu Kozawa
Phosphatidylinositol 3-kinase/Akt auto-regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts.
Journal of cellular biochemistry 2006;99(6):1564-71.
2006: Shinji Takai; Haruhiko Tokuda; Yoshiteru Hanai; Osamu Kozawa
Phosphatidylinositol 3-kinase/Akt plays a part in tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblasts.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(9):563-9.
2006: Kumiko Tanabe; Haruhiko Tokuda; Shinji Takai; Rie Matsushima-Nishiwaki; Yoshiteru Hanai; Kouseki Hirade; Yoshihiro Katagiri; Shuji Dohi; Osamu Kozawa
Modulation by the steroid/thyroid hormone superfamily of TGF-beta-stimulated VEGF release from vascular smooth muscle cells.
Journal of cellular biochemistry 2006;99(1):187-95.
2006: Shinji Takai; Haruhiko Tokuda; Minoru Yoshida; Eisuke Yasuda; Rie Matsushima-Nishiwaki; Atsushi Harada; Kanefusa Kato; Osamu Kozawa
Prostaglandin D2 induces the phosphorylation of HSP27 in osteoblasts: function of the MAP kinase superfamily.
Prostaglandins, leukotrienes, and essential fatty acids 2006;75(2):61-7.
2006: Shinji Takai; Haruhiko Tokuda; Rie Matsushima-Nishiwaki; Yoshiteru Hanai; Kanefusa Kato; Osamu Kozawa
Phosphatidylinositol 3-kinase/Akt plays a role in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts.
Journal of cellular biochemistry 2006;98(5):1249-56.
2006: Yoshiteru Hanai; Haruhiko Tokuda; Akira Ishisaki; Rie Matsushima-Nishiwaki; Norimi Nakamura; Minoru Yoshida; Shinji Takai; Toshiki Ohta; Osamu Kozawa
Involvement of p44/p42 MAP kinase in insulin-like growth factor-I-induced alkaline phosphatase activity in osteoblast-like-MC3T3-E1 cells.
Molecular and cellular endocrinology 2006;251(1-2):42-8.
2006: Yoshiteru Hanai; Haruhiko Tokuda; Shinji Takai; Atsushi Harada; Toshiki Ohta; Osamu Kozawa
Minodronate suppresses prostaglandin F2alpha-induced vascular endothelial growth factor synthesis in osteoblasts.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(3):152-8.
2005: Minoru Yoshida; Haruhiko Tokuda; Akira Ishisaki; Yosuke Kanno; Atsushi Harada; Katsuji Shimuzu; Osamu Kozawa
Tiludronate inhibits prostaglandin F2alpha-induced vascular endothelial growth factor synthesis in osteoblasts.
Molecular and cellular endocrinology 2005;236(1-2):59-66.
2005: Takahiro Noda; Haruhiko Tokuda; Minoru Yoshida; Eisuke Yasuda; Yoshiteru Hanai; Shinji Takai; Osamu Kozawa
Possible involvement of phosphatidylinositol 3-kinase/Akt pathway in insulin-like growth factor-I-induced alkaline phosphatase activity in osteoblasts.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(5):270-4.
2005: Minoru Yoshida; Yosuke Kanno; Akira Ishisaki; Haruhiko Tokuda; Kouseki Hirade; Keiichi Nakajima; Yoshihiro Katagiri; Katsuji Shimizu; Osamu Kozawa
Methotrexate suppresses inflammatory agonist induced interleukin 6 synthesis in osteoblasts.
The Journal of rheumatology 2005;32(5):787-95.
2005: Eisuke Yasuda; Haruhiko Tokuda; Akira Ishisaki; Kouseki Hirade; Yosuke Kanno; Yoshiteru Hanai; Norimi Nakamura; Takahiro Noda; Yoshihiro Katagiri; Osamu Kozawa
PPAR-gamma ligands up-regulate basic fibroblast growth factor-induced VEGF release through amplifying SAPK/JNK activation in osteoblasts.
Biochemical and biophysical research communications 2005;328(1):137-43.
2005: Yosuke Kanno; Akira Ishisaki; Minoru Yoshida; Keiichi Nakajima; Haruhiko Tokuda; Osamu Numata; Osamu Kozawa
Adenylyl cyclase-cAMP system inhibits thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.
Molecular and cellular endocrinology 2005;229(1-2):75-82.