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Barbara Tolusso

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Lymphocyte Depletion

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Elisa Gremese; Barbara Tolusso; Stefano Alivernini; Silvia Canestri; Anna Laura Fedele; Gianfranco Ferraccioli
ZAP-70+ B cell subset influences response to B cell depletion therapy and early repopulation in rheumatoid arthritis.
Maria De Santis; Mario Bocci; Silvia Laura Bosello; Ettore Capoluongo; Massimo Castagnola; Rosanna Inzitari; Paola Lulli; Giusy Peluso; Barbara Tolusso; Gaetano Zizzo; Cecilia Zuppi; Gianfranco Ferraccioli
A vascular endothelial growth factor deficiency characterises scleroderma lung disease.
Domenico Frezza; Vincenzo Giambra; Elisa Gremese; Maurizio Marchini; Claudia Mattioli; Marcin Nowik; Luca Petricca; Raffaella Scorza; Eliseo Serone; Barbara Tolusso; Barbara K Birshtein; Silvia Canestri; Pietro D'Addabbo; Graziella D'Antona; Gianfranco Ferraccioli
Polymorphisms of the IgH enhancer HS1.2 and risk of systemic lupus erythematosus.

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All Publications

2012: Elisa Gremese; Barbara Tolusso; Stefano Alivernini; Silvia Canestri; Anna Laura Fedele; Gianfranco Ferraccioli
ZAP-70+ B cell subset influences response to B cell depletion therapy and early repopulation in rheumatoid arthritis.
The Journal of rheumatology 2012;39(12):2276-85.
2012: Maria De Santis; Mario Bocci; Silvia Laura Bosello; Ettore Capoluongo; Massimo Castagnola; Rosanna Inzitari; Paola Lulli; Giusy Peluso; Barbara Tolusso; Gaetano Zizzo; Cecilia Zuppi; Gianfranco Ferraccioli
A vascular endothelial growth factor deficiency characterises scleroderma lung disease.
Annals of the rheumatic diseases 2012;71(9):1461-5.
2012: Domenico Frezza; Vincenzo Giambra; Elisa Gremese; Maurizio Marchini; Claudia Mattioli; Marcin Nowik; Luca Petricca; Raffaella Scorza; Eliseo Serone; Barbara Tolusso; Barbara K Birshtein; Silvia Canestri; Pietro D'Addabbo; Graziella D'Antona; Gianfranco Ferraccioli
Polymorphisms of the IgH enhancer HS1.2 and risk of systemic lupus erythematosus.
Annals of the rheumatic diseases 2012;71(8):1309-15.
2012: S Canestri; Domenico Frezza; Elisa Gremese; E Serone; Barbara Tolusso; M C Totaro; Gianfranco Ferraccioli
Association between the response to B cell depletion therapy and the allele*2 of the HS1,2A enhancer in seropositive rheumatoid arthritis patients.
Reumatismo 2012;64(6):368-73.
2012: Gianfranco Ferraccioli; Elisa Gremese; Bruno Laganà; Mariangela Manfredi; Alice Mannocci; Fabiola Atzeni; Maurizio Benucci; Domenico Biasi; Francesca Bobbio-Pallavicini; Elisabetta Podestà; Viviana Ravagnani; Piercarlo Sarzi Puttini; Barbara Tolusso; Carlomaurizio Montecucco
Biomarkers of good EULAR response to the B cell depletion therapy in all seropositive rheumatoid arthritis patients: clues for the pathogenesis.
PloS one 2012;7(7):e40362.
2011: Alessandro Michelutti; Francesca Morassi; Giusy Peluso; Luca Petricca; Barbara Tolusso; Stefano Alivernini; Vincenzo Arena; Silvia Laura Bosello; Elisa Gremese; Gianfranco Ferraccioli
B-cell subsets in the joint compartments of seropositive and seronegative rheumatoid arthritis (RA) and No-RA arthritides express memory markers and ZAP70 and characterize the aggregate pattern irrespectively of the autoantibody status.
Molecular medicine (Cambridge, Mass.) 2011;17(9-10):901-9.
2011: Silvia Bosello; Giacomo De Luca; Gina Lama; Gigliola Sica; Barbara Tolusso; Cristiana Angelucci; Gianfranco Ferraccioli
B cells in systemic sclerosis: a possible target for therapy.
Autoimmunity reviews 2011;10(10):624-30.
2011: Silvia Bosello; Anna Laura Fedele; Giusy Peluso; Elisa Gremese; Barbara Tolusso; Gianfranco Ferraccioli
Very early rheumatoid arthritis is the major predictor of major outcomes: clinical ACR remission and radiographic non-progression.
Annals of the rheumatic diseases 2011;70(7):1292-5.
2011: Michele Ciro Totaro; Stefano Alivernini; Silvia Laura Bosello; Silvia Canestri; Francesca Faustini; Elisa Gremese; Alice Mannocci; Valerio Napolioni; Barbara Tolusso; Gianfranco Ferraccioli
PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis.
PloS one 2011;6(9):e24292.
2011: Giusy Peluso; Alessandro Michelutti; Silvia Bosello; Elisa Gremese; Barbara Tolusso; Gianfranco Ferraccioli
Clinical and ultrasonographic remission determines different chances of relapse in early and long standing rheumatoid arthritis.
Annals of the rheumatic diseases 2011;70(1):172-5.
2011: Gaetano Zizzo; Maria De Santis; Silvia Laura Bosello; Anna Laura Fedele; Giusy Peluso; Elisa Gremese; Barbara Tolusso; Gianfranco Ferraccioli
Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis.
Clinical immunology (Orlando, Fla.) 2011;138(1):107-16.
2010: Gianfranco Ferraccioli; Luisa Bracci-Laudiero; Stefano Alivernini; Elisa Gremese; Barbara Tolusso; Fabrizio De Benedetti
Interleukin-1β and interleukin-6 in arthritis animal models: roles in the early phase of transition from acute to chronic inflammation and relevance for human rheumatoid arthritis.
Molecular medicine (Cambridge, Mass.) 2010;16(11-12):552-7.
2010: Donatello Pietrapertosa; Barbara Tolusso; Elisa Gremese; Maria Concetta Papalia; Silvia Laura Bosello; Giusy Peluso; Luca Petricca; Alessandro Michelutti; Francesca Faustini; Anna Laura Fedele; Gianfranco Ferraccioli
Diagnostic performance of anti-citrullinated peptide antibodies for the diagnosis of rheumatoid arthritis: the relevance of likelihood ratios.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2010;48(6):829-34.
2010: Silvia Bosello; Maria De Santis; Gina Lama; Cristina Spanò; Cristiana Angelucci; Barbara Tolusso; Gigliola Sica; Gianfranco Ferraccioli
B cell depletion in diffuse progressive systemic sclerosis: safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial.
Arthritis research & therapy 2010;12(2):R54.
2009: Barbara Tolusso; Maria De Santis; Silvia Bosello; Elisa Gremese; Stefania Gobessi; Ilaria Cuoghi; Michele C Totaro; Giulio Bigotti; Carlo Rumi; Dimitar G Efremov; Gianfranco Ferraccioli
Synovial B cells of rheumatoid arthritis express ZAP-70 which increases the survival and correlates with the inflammatory and autoimmune phenotype.
Clinical immunology (Orlando, Fla.) 2009;131(1):98-108.
2009: Stefano Alivernini; Maria De Santis; Barbara Tolusso; Alice Mannocci; Silvia Laura Bosello; Giusy Peluso; Michela Pinnelli; Graziella D'Antona; Giuseppe LaTorre; Gianfranco Ferraccioli
Skin ulcers in systemic sclerosis: determinants of presence and predictive factors of healing.
Journal of the American Academy of Dermatology 2009;60(3):426-35.
2009: Barbara Tolusso; D Frezza; C Mattioli; A L Fedele; Silvia Bosello; F Faustini; G Peluso; Vincenzo Giambra; D Pietrapertosa; A Morelli; Elisa Gremese; Marco De Santis; Gianfranco F Ferraccioli
Allele *2 of the HS1,2A enhancer of the Ig regulatory region associates with rheumatoid arthritis.
Annals of the rheumatic diseases 2009;68(3):416-9.
2008: Silvia Bosello; Pierre Youinou; Capucine Daridon; Barbara Tolusso; Boutahar Bendaoud; Donatello Pietrapertosa; Alessia Morelli; Gianfranco Ferraccioli
Concentrations of BAFF correlate with autoantibody levels, clinical disease activity, and response to treatment in early rheumatoid arthritis.
The Journal of rheumatology 2008;35(7):1256-64.
2008: S Alivernini; A L Fedele; I Cuoghi; Barbara Tolusso; Gianfranco Ferraccioli
Citrullination: the loss of tolerance and development of autoimmunity in rheumatoid arthritis.
Reumatismo 2008;60(2):85-94.
2007: Gianfranco Ferraccioli; Barbara Tolusso
Infections, B cell receptor activation and autoimmunity: different check-point impairments lead to autoimmunity, clonal B cell expansion and fibrosis in different immunological settings.
Autoimmunity reviews 2007;7(2):109-13.
2007: Domenico Frezza; Vincenzo Giambra; Barbara Tolusso; M De Santis; Silvia Bosello; S Vettori; G Triolo; G Valentini; Gianfranco Ferraccioli
Polymorphism of immunoglobulin enhancer element HS1,2A: allele *2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency.
Annals of the rheumatic diseases 2007;66(9):1210-5.
2007: Marco Maria Lizzio; Giusy Peluso; Angelo Zoli; Elisa Gremese; Barbara Tolusso; Gianfranco Ferraccioli
Analysis of response to infliximab in ankylosing spondylitis according to the axial and/or peripheral involvement: autoantibodies and drop outs are more frequent in the peripheral subset.
Annals of the rheumatic diseases 2007;66(3):427-8.
2007: Gianfranco Ferraccioli; Barbara Tolusso; Maria De Santis
Pharmacogenetic of antirheumatic treatments: clinical implications.
The pharmacogenomics journal 2007;7(1):2-9.
2006: Barbara Tolusso; Donatello Pietrapertosa; Alessia Morelli; Maria De Santis; Elisa Gremese; Giuseppina Farina; Siro Giorgio Carniello; Marino Del Frate; Gianfranco Ferraccioli
IL-1B and IL-1RN gene polymorphisms in rheumatoid arthritis: relationship with protein plasma levels and response to therapy.
Pharmacogenomics 2006;7(5):683-95.
2005: Silvia Bosello; Maria De Santis; Barbara Tolusso; Angelo Zoli; Gianfranco Ferraccioli
Tumor necrosis factor-alpha inhibitor therapy in erosive polyarthritis secondary to systemic sclerosis.
Annals of internal medicine 2005;143(12):918-20.
2005: Martina Fabris; Barbara Tolusso; Emma Di Poi; Paola Tomietto; Stefania Sacco; Elisa Gremese; Gianfranco Ferraccioli
Mononuclear cell response to lipopolysaccharide in patients with rheumatoid arthritis: relationship with tristetraprolin expression.
The Journal of rheumatology 2005;32(6):998-1005.
2005: Barbara Tolusso; Martina Fabris; Roberto Caporali; Giovanna Cuomo; Miriam Isola; Franca Soldano; Carlomaurizio Montecucco; Gabriele Valentini; Gianfranco Ferraccioli
-238 and +489 TNF-alpha along with TNF-RII gene polymorphisms associate with the diffuse phenotype in patients with Systemic Sclerosis.
Immunology letters 2005;96(1):103-8.
2005: Maria De Santis; Silvia Bosello; Giuseppe La Torre; Anna Capuano; Barbara Tolusso; Gabriella Pagliari; Riccardo Pistelli; Francesco Maria Danza; Angelo Zoli; Gianfranco Ferraccioli
Functional, radiological and biological markers of alveolitis and infections of the lower respiratory tract in patients with systemic sclerosis.
Respiratory research 2005;6():96.
2004: Barbara Tolusso; Stefania Sacco; Elisa Gremese; G La Torre; Paola Tomietto; Gianfranco F Ferraccioli
Relationship between the tumor necrosis factor receptor II (TNF-RII) gene polymorphism and sTNF-RII plasma levels in healthy controls and in rheumatoid arthritis.
Human immunology 2004;65(12):1420-6.
2004: Gianfranco Ferraccioli; Maria De Santis; Barbara Tolusso
Pharmacogenetics/pharmacogenomics and antirheumatic drugs in rheumatology.
Pharmacogenomics 2004;5(8):1107-16.
2004: Paola Tomietto; Elisa Gremese; Barbara Tolusso; Paolo Venturini; Salvatore De Vita; Gianfranco Ferraccioli
B cell depletion may lead to normalization of anti-platelet, anti-erythrocyte and antiphospholipid antibodies in systemic lupus erythematosus.
Thrombosis and haemostasis 2004;92(5):1150-3.
2004: Martina Fabris; Barbara Tolusso; Elisa Gremese; Paola Tomietto; Gianfranco Ferraccioli
[Analysis of the kinetic of expression of tristetraprolin and HuR by rheumatoid arthritis patients peripheral blood mononuclear cells stimulated with lipopolysaccharide].
Reumatismo 2004;56(2):94-103.
2003: Barbara Tolusso; Martina Fabris; Elisa Gremese; M Mosca; Patrizia Rovere-Querini; Gianfranco F Ferraccioli
Platelet GPIIb/IIIa (P1A 1/2) polymorphism in SLE: clinical and laboratory association.
Annals of the rheumatic diseases 2003;62(8):781-2.
2003: Barbara Tolusso; Martina Fabris; Emma Di Poi; Roberta Assaloni; Paola Tomietto; Gianfranco F Ferraccioli
Response of mononuclear cells to lipopolysaccharide and CpG oligonucleotide stimulation: possible additive effect in rheumatoid inflammation.
Annals of the rheumatic diseases 2003;62(3):284-5.
2002: Martina Fabris; Barbara Tolusso; Emma Di Poi; Roberta Assaloni; Luigi Sinigaglia; Gianfranco Ferraccioli
Tumor necrosis factor-alpha receptor II polymorphism in patients from southern Europe with mild-moderate and severe rheumatoid arthritis.
The Journal of rheumatology 2002;29(9):1847-50.