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Georgia Tomaras

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Vainav Patel; Candido Alicea; Rama R Amara; Julian W Bess; Kate E Broderick; Barbara K Felber; Yongjun Guan; Vanessa M Hirsch; Wensheng Huang; Rashmi Jalah; Welkin Johnson; Brandon F Keele; Viraj Kulkarni; Jeffrey D Lifson; Michael Piatak; Harriet L Robinson; Margherita Rosati; Niranjan Y Sardesai; Xiaoying Shen; Georgia D Tomaras; Antonio Valentin; David J Venzon; Agneta S von Gegerfelt; William T Williams; George Pavlakis
DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.
Poonam Pegu; Mangala Rao; Donald Stablein; Jim Tartaglia; Georgia D Tomaras; Monica Vaccari; David Venzon; Stephen Whitney; Shari Gordon; Yongjun Guan; Lauren Hudacik; Brandon F Keele; Jerome Kim; Jeffrey D Lifson; Nelson Michael; David Montefiori; Ranajit Pal; S Munir Alam; Erik Billings; Melvin Doster; Claudio Fenizia; Guido Ferrari; Maria Grazia Ferrari; Genoveffa Franchini
Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial.
Susan Zolla-Pazner; Charla Andrews; Robert T Bailer; Phillip Berman; Erik Billings; Timothy Cardozo; Mark de Souza; Allan C deCamp; Peter B Gilbert; Raphael Gottardo; Barton F Haynes; Nicos Karasavvas; Bette Korber; Richard Koup; John R Mascola; Nelson L Michael; David Montefiori; Daryl E Morris; Viseth Ngauy; Sorachai Nitayaphan; Robert J O'Connell; Abraham Pinter; Mangala Rao; Supachai Rerks-Ngarm; Merlin L Robb; Xiaoying Shen; Georgia D Tomaras; Constance Williams; Jerome H Kim
Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial.

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2013: Vainav Patel; Candido Alicea; Rama R Amara; Julian W Bess; Kate E Broderick; Barbara K Felber; Yongjun Guan; Vanessa M Hirsch; Wensheng Huang; Rashmi Jalah; Welkin Johnson; Brandon F Keele; Viraj Kulkarni; Jeffrey D Lifson; Michael Piatak; Harriet L Robinson; Margherita Rosati; Niranjan Y Sardesai; Xiaoying Shen; Georgia D Tomaras; Antonio Valentin; David J Venzon; Agneta S von Gegerfelt; William T Williams; George Pavlakis
DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(8):2975-80.
2013: Poonam Pegu; Mangala Rao; Donald Stablein; Jim Tartaglia; Georgia D Tomaras; Monica Vaccari; David Venzon; Stephen Whitney; Shari Gordon; Yongjun Guan; Lauren Hudacik; Brandon F Keele; Jerome Kim; Jeffrey D Lifson; Nelson Michael; David Montefiori; Ranajit Pal; S Munir Alam; Erik Billings; Melvin Doster; Claudio Fenizia; Guido Ferrari; Maria Grazia Ferrari; Genoveffa Franchini
Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial.
Journal of virology 2013;87(3):1708-19.
2013: Susan Zolla-Pazner; Charla Andrews; Robert T Bailer; Phillip Berman; Erik Billings; Timothy Cardozo; Mark de Souza; Allan C deCamp; Peter B Gilbert; Raphael Gottardo; Barton F Haynes; Nicos Karasavvas; Bette Korber; Richard Koup; John R Mascola; Nelson L Michael; David Montefiori; Daryl E Morris; Viseth Ngauy; Sorachai Nitayaphan; Robert J O'Connell; Abraham Pinter; Mangala Rao; Supachai Rerks-Ngarm; Merlin L Robb; Xiaoying Shen; Georgia D Tomaras; Constance Williams; Jerome H Kim
Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial.
PloS one 2013;8(1):e53629.
2012: Mattia Bonsignori; Barton F Haynes; Hua-Xin Liao; Georgia D Tomaras; Laurent Verkoczy; S Munir Alam; M Anthony Moody
HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design.
Trends in microbiology 2012;20(11):532-9.
2012: Mattia Bonsignori; Xi Chen; Anthony DeVico; David T Evans; Guido Ferrari; Peter B Gilbert; Thaddeus C Gurley; Michael D Alpert; Ying Huang; Kwan-Ki Hwang; Jaranit Kaewkungwal; Jerome H Kim; Daniel M Kozink; George K Lewis; Hua-Xin Liao; Dawn J Marshall; Nelson L Michael; David C Montefiori; M Anthony Moody; Sorachai Nitayaphan; Punnee Pitisuttithum; Justin Pollara; Supachai Rerks-Ngarm; Georgia D Tomaras; Chun-Yen Tsao; John F Whitesides; Barton F Haynes
Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family.
Journal of virology 2012;86(21):11521-32.
2012: Constantinos Petrovas; Amanda Poholek; SRINIVAS RAO; Mario Roederer; Netanya G Sandler; Robert A Seder; Emily C Smith; Xiaoyong Sun; Katherina J Timmer; Georgia D Tomaras; Kaska Wloka; Takuya Yamamoto; S Munir Alam; David R Ambrozak; Kristin L Boswell; Jason M Brenchley; Daniel C Douek; Ronald N Germain; Michael Y Gerner; Elias K Haddad; Li Pan; Richard A Koup
CD4 T follicular helper cell dynamics during SIV infection.
The Journal of clinical investigation 2012;122(9):3281-94.
2012: Rebecca M Lynch; Salim Abdool Karim; Myron Cohen; Rebecca DerSimonian; Zelda Euler; Elin S Gray; Barton F Haynes; Jennifer Kirchherr; Mark K Louder; David C Montefiori; Lynn Morris; Gary Nabel; Stephen D Schmidt; Hanneke Schuitemaker; Sengeziwe Sibeko; Kelly Soderberg; Georgia D Tomaras; Lillian Tran; Zhi-Yong Yang; John R Mascola
The development of CD4 binding site antibodies during HIV-1 infection.
Journal of virology 2012;86(14):7588-95.
2012: M Anthony Moody; Robert Parks; Joy Pickeral; Justin Pollara; Julia Cavanaugh Scull; Georgia D Tomaras; Nathan A Vandergrift; Gerald Voss; Lu Wang; John F Whitesides; Nicole L Yates; Jae-Sung Yu; Ruijun Zhang; S Munir Alam; Joshua D Amos; Xi Chen; Mark S Drinker; Joshua A Eudailey; Guido Ferrari; Andrew Foulger; Thaddeus C Gurley; Garnett Kelsoe; Hua-Xin Liao; Dawn J Marshall; R Ryan Meyerhoff; David C Montefiori; Barton F Haynes
HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.
Journal of virology 2012;86(14):7496-507.
2012: Stephanie A Freel; Barton F Haynes; John C Kappes; Jennifer L Kirchherr; Andrew J McMichael; Christina Ochsenbauer; Ralph A Picking; Kelly A Soderberg; Myron S Cohen; John A Crump; Coleen K Cunningham; Thomas N Denny; Haitao Ding; Guido Ferrari; Kent J Weinhold; Georgia D Tomaras
Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication.
Journal of virology 2012;86(12):6835-46.
2012: Marc A Frahm; Cynthia L Gay; Charles B Hicks; JoAnn D Kuruc; Kara S McGee; Ralph A Picking; Georgia D Tomaras; Joseph J Eron; Guido Ferrari
CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(9):4289-96.
2012: Mattia Bonsignori; Xi Chen; John A Crump; Kwan-Ki Hwang; Saidi H Kapiga; Thomas B Kepler; Daniel M Kozink; Peter D Kwong; Hua-Xin Liao; John R Mascola; David C Montefiori; Robert J Parks; Noel E Sam; Georgia D Tomaras; Chun-Yen Tsao; Xueling Wu; Barton F Haynes
Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design.
Journal of virology 2012;86(8):4688-92.
2012: James Friedman; Barton F Haynes; Garnett Kelsoe; Hua-Xin Liao; M Anthony Moody; S Munir Alam; Kara Anasti; Guido Ferrari; Genevieve G Fouda; Justin Pollara; Xiaoying Shen; Shelley Stewart; Georgia D Tomaras; Shi-Mao Xia; Guang Yang; Sallie R Permar
Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum.
PloS one 2012;7(5):e37648.
2011: Lindsey R Baden; Dan H Barouch; William A Blattner; Kara Brandariz; Massimo Cardinali; Olivier D Defawe; Raphael Dolin; Barney S Graham; Yunda Huang; Nidhi Kochar; M Juliana McElrath; Cecilia Morgan; Nina Russell; Magdalena E Sobieszczyk; Georgia D Tomaras
Timing of plasmid cytokine (IL-2/Ig) administration affects HIV-1 vaccine immunogenicity in HIV-seronegative subjects.
The Journal of infectious diseases 2011;204(10):1541-9.
2011: Nicole L Yates; Nathan A Vandergrift; Myron S Cohen; Thomas N Denny; Barton F Haynes; Judith T Lucas; Tracy L Nolen; Kelly E Seaton; Kelly A Soderberg; Georgia D Tomaras
Multiple HIV-1-specific IgG3 responses decline during acute HIV-1: implications for detection of incident HIV infection.
AIDS (London, England) 2011;25(17):2089-97.
2011: S Munir Alam; Kara Anasti; Bing Chen; S Moses Dennison; Michele Donathan; Andrew Foulger; Frederick Jaeger; Garnett Kelsoe; Thomas B Kepler; Hua-Xin Liao; Judith Lucas; Nathan Nicely; Robert Parks; Georgia D Tomaras; Laurent Verkoczy; Barton F Haynes
Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation.
Journal of virology 2011;85(22):11725-31.
2011: Zhongyu Zhu; Weizao Chen; Genevieve G Fouda; Barton F Haynes; Kristina-Ana Klaric; Peter D Kwong; Hua-Xin Liao; Mark K Louder; John R Mascola; David Montefiori; M Anthony Moody; Gilad Ofek; John Owens; Prabakaran Ponraj; Haiyan Rebekah Qin; Robert Schutte; Jamie K Scott; Xiaoying Shen; Emily Streaker; Georgia D Tomaras; Yanping Wang; Yongping Yang; Qi Zhao; Dimiter S Dimitrov
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies.
Journal of virology 2011;85(21):11401-8.
2011: Pinghuang Liu; David C Montefiori; Christina Ochsenbauer; R Glenn Overman; Alan S Perelson; Nathan Vandergrift; Nicole L Yates; S Munir Alam; Yue Chen; Myron S Cohen; Stephanie A Freel; Feng Gao; Frederik Graw; Barton F Haynes; John C Kappes; Georgia D Tomaras
Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infection.
Journal of virology 2011;85(21):11196-207.
2011: Georgia D Tomaras; Tommy Tong; Nancy Tumba; Constantinos Kurt Wibmer; Nicole L Yates; Keiko Osawa; George M Shaw; Xiaoying Shen; Salim S Abdool-Karim; S Munir Alam; James M Binley; Myron Cohen; Emma T Crooks; John A Crump; Julie Decker; Philippa Easterbrook; Feng Gao; Elin S Gray; Barton F Haynes; Gift Kamanga; John R Mascola; David C Montefiori; Penny L Moore; Lynn Morris
Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals.
Journal of virology 2011;85(21):11502-19.
2011: Chunlai Jiang; Hui Li; Xiaozhi Lu; M Anthony Moody; Donald E Mosier; Rebecca Nedellec; Nicholas F Parrish; Jeffrey W Pavlicek; Jennifer M Pfaff; Robert Schutte; George M Shaw; Hongshuo Song; John C Tilton; Georgia D Tomaras; Craig B Wilen; Anna Berg; Yue Chen; Julie M Decker; Robert W Doms; Mark S Drinker; Stephanie Freel; Beatrice H Hahn; Barton F Haynes; Elizabeth A Henning; Feng Gao
Primary infection by a human immunodeficiency virus with atypical coreceptor tropism.
Journal of virology 2011;85(20):10669-81.
2011: Stephen C De Rosa; Allan deCamp; Barney S Graham; Yunda Huang; Spyros A Kalams; Chuen-Yen Lau; M Juliana McElrath; Cecilia Morgan; Gary Nabel; Evan P Thomas; Georgia D Tomaras; Rafi Ahmed; Rama Akondy; John Bui
HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(6):3391-401.
2011: Ben-Jiang Ma; Sampa Santra; Richard M Scearce; Laura L Sutherland; Georgia D Tomaras; S Munir Alam; Cindy Bowman; Heather Desaire; Eden P Go; Thomas B Kepler; Norman L Letvin; Hua-Xin Liao; Xiaozhi Lu; Barton F Haynes
Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies.
PLoS pathogens 2011;7(9):e1002200.
2011: Genevieve G Fouda; Beatrice H Hahn; Barton Haynes; Linda Kalilani-Phiri; Helen H Kang; Norman L Letvin; Rachel V Lovingood; Tatenda Mahlokozera; Steve R Meshnick; David C Montefiori; Glenn R Overman; Sallie R Permar; Justin Pollara; Maria G Salazar; Jesus F Salazar-Gonzalez; George M Shaw; Xiaoying Shen; Georgia D Tomaras; Andrew B Wilks; Nicole L Yates; Thomas N Denny; Guido Ferrari
HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.
Journal of virology 2011;85(18):9555-67.
2011: Justin Pollara; Mario Roederer; Georgia D Tomaras; Kent J Weinhold; Faraha Brewer; Lydia Hart; Barton F Haynes; James A Hoxie; Ying Huang; John C Kappes; Akira Komoriya; David C Montefiori; Christina Ochsenbauer; Beverly Z Packard; Joy Pickeral; Guido Ferrari
High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011;79(8):603-12.
2011: Elin S Gray; Barton F Haynes; Bronwen Lambson; Salim S Abdool-Karim; Joshua Amos; Xi Chen; Andrew Foulger; Dawn Marshall; M Anthony Moody; Penny L Moore; Lynn Morris; Georgia D Tomaras; John F Whitesides; Constantinos Kurt Wibmer; Jae-Sung Yu; Hua-Xin Liao
Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual.
Journal of virology 2011;85(15):7719-29.
2011: Guido Ferrari; Stephanie Freel; Tiara Harms; S Munir Alam; Mark Drinker; James A Hoxie; John C Kappes; Daniel Kozink; M Anthony Moody; Christina Ochsenbauer; Justin Pollara; James E Robinson; George M Shaw; Georgia D Tomaras; Barton F Haynes
An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum.
Journal of virology 2011;85(14):7029-36.
2011: Barbara J Flynn; Kathrin Kastenmüller; Ulrike Wille-Reece; Georgia D Tomaras; Munir Alam; Ross W Lindsay; Andres M Salazar; Beatriz Perdiguero; Carmen E Gomez; Ralf Wagner; Mariano Esteban; Chae G Park; Christine Trumpfheller; Tibor Keler; Giuseppe Pantaleo; Ralph M Steinman; Robert A Seder
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(17):7131-6.
2011: Paul Spearman; Michelle A Lally; Marnie Elizaga; David Montefiori; Georgia D Tomaras; M Juliana McElrath; John Hural; Stephen C De Rosa; Alicia Sato; Yunda Huang; Sharon E Frey; Paul Sato; John Donnelly; Susan Barnett; Lawrence J Corey
A trimeric, V2-deleted HIV-1 envelope glycoprotein vaccine elicits potent neutralizing antibodies but limited breadth of neutralization in human volunteers.
The Journal of infectious diseases 2011;203(8):1165-73.
2011: Stephanie A Freel; Kevin O Saunders; Georgia D Tomaras
CD8(+)T-cell-mediated control of HIV-1 and SIV infection.
Immunologic research 2011;49(1-3):135-46.
2011: Paul A Goepfert; Marnie L Elizaga; Alicia Sato; Li Qin; Massimo Cardinali; Christine M Hay; John Hural; Stephen C DeRosa; Olivier D Defawe; Georgia D Tomaras; David C Montefiori; Yongxian Xu; Lilin Lai; Spyros A Kalams; Lindsey R Baden; Sharon E Frey; William A Blattner; Linda S Wyatt; Bernard Moss; Harriet L Robinson
Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles.
The Journal of infectious diseases 2011;203(5):610-9.
2011: Xiaoying Shen; Georgia D Tomaras
Alterations of the B-cell response by HIV-1 replication.
Current HIV/AIDS reports 2011;8(1):23-30.
2011: Barton F Haynes; M Anthony Moody; Hua-Xin Liao; Laurent Verkoczy; Georgia D Tomaras
B cell responses to HIV-1 infection and vaccination: pathways to preventing infection.
Trends in molecular medicine 2011;17(2):108-16.
2011: S Moses Dennison; S Munir Alam; Kara M Anasti; Cindy Bowman; Bing Chen; Frederick H Jaeger; Peter D Kwong; Norman L Letvin; Hua-Xin Liao; Gilad Ofek; Robert Parks; Sampa Santra; Richard M Scearce; Xiaoying Shen; Shelley Stewart; Laura L Sutherland; Georgia D Tomaras; Shi-Mao Xia; Yongping Yang; Ruijun Zhang; Barton F Haynes
Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.
PloS one 2011;6(11):e27824.
2011: Lynn Morris; Robert Parks; Georgia D Tomaras; John Whitesides; Ruijun Zhang; Frederick Jaeger; Thomas B Kepler; Hua-Xin Liao; Dawn J Marshall; David Montefiori; M Anthony Moody; Salim S Abdool-Karim; Munir Alam; Mira Bilska; Bing Chen; Xi Chen; Michele Donathan; Andrew Foulger; Elin S Gray; Barton F Haynes
Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting.
PloS one 2011;6(9):e23532.
2011: Beryl A Koblin; Chuen-Yen Lau; M Juliana McElrath; David C Montefiori; Cecilia Morgan; Li Qin; Lilian Saavedra; Georgia D Tomaras; Zhixue Maggie Wang; Lindsey Baden; Martin Casapía; Olivier D Defawe; Paul Goepfert; Barney S Graham
Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial.
PloS one 2011;6(9):e24517.
2011: Gavin J Churchyard; Lawrence Corey; Stephen C De Rosa; Olivier Defawe; Raphael Dolin; J Peter Figueroa; Paul Goepfert; Barney S Graham; Glenda Gray; Doug Grove; John Hural; Spyros Kalams; Artur Kalichman; Michael C Keefer; Michelle Lally; M Juliana McElrath; David C Montefiori; Zoe Moodie; Cecilia Morgan; Gary Nabel; Jean Pape; Mauro Schechter; Georgia D Tomaras; Elizabeth Adams; Lindsey R Baden; Linda-Gail Bekker; William A Blattner
A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204).
PloS one 2011;6(8):e21225.
2011: Guido Ferrari; Bette Korber; Nilu Goonetilleke; Michael K P Liu; Emma L Turnbull; Jesus F Salazar-Gonzalez; Natalie Hawkins; Steve Self; Sydeaka Watson; Michael R Betts; Cynthia Gay; Kara McGhee; Pierre Pellegrino; Ian Williams; Georgia D Tomaras; Barton F Haynes; Clive M Gray; Persephone Borrow; Mario Roederer; Andrew J McMichael; Kent J Weinhold
Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.
PLoS pathogens 2011;7(2):e1001273.
2010: Jinyan Liu; Brandon F Keele; Hui Li; Sheila Keating; Philip J Norris; Angela Carville; Keith G Mansfield; Georgia D Tomaras; Barton F Haynes; Dror Kolodkin-Gal; Norman L Letvin; Beatrice H Hahn; George M Shaw; Dan H Barouch
Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys.
Journal of virology 2010;84(19):10406-12.
2010: Kevin O Saunders; Stephanie A Freel; R Glenn Overman; Coleen K Cunningham; Georgia D Tomaras
Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication.
Virology 2010;405(1):234-42.
2010: Georgia D Tomaras; Barton F Haynes
Strategies for eliciting HIV-1 inhibitory antibodies.
Current opinion in HIV and AIDS 2010;5(5):421-7.
2010: Barton F Haynes; Hua-Xin Liao; Georgia D Tomaras
Is developing an HIV-1 vaccine possible?
Current opinion in HIV and AIDS 2010;5(5):362-7.
2010: M Anthony Moody; Hua-Xin Liao; S Munir Alam; Richard M Scearce; M Kelly Plonk; Daniel M Kozink; Mark S Drinker; Ruijun Zhang; Shi-Mao Xia; Laura L Sutherland; Georgia D Tomaras; Ian P Giles; John C Kappes; Christina Ochsenbauer-Jambor; Tara G Edmonds; Melina Soares; Gustavo Barbero; Donald N Forthal; Gary Landucci; Connie Chang; Steven W King; Anita Kavlie; Thomas N Denny; Kwan-Ki Hwang; Pojen P Chen; Philip E Thorpe; David C Montefiori; Barton F Haynes
Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines.
The Journal of experimental medicine 2010;207(4):763-76.
2010: Xiaoying Shen; S Moses Dennison; Pinghuang Liu; Feng Gao; Frederick Jaeger; David C Montefiori; Laurent Verkoczy; Barton F Haynes; S Munir Alam; Georgia D Tomaras
Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(13):5972-7.
2010: Avishek Nandi; Christine L Lavine; Pengcheng Wang; Inna Lipchina; Paul A Goepfert; George M Shaw; Georgia D Tomaras; David C Montefiori; Barton F Haynes; Philippa Easterbrook; James E Robinson; Joseph G Sodroski; Xinzhen Yang
Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1.
Virology 2010;396(2):339-48.
2010: Laurence Peiperl; Cecilia Morgan; Zoe Moodie; Hongli Li; Nina Russell; Barney S Graham; Georgia D Tomaras; Stephen C De Rosa; M Juliana McElrath
Safety and immunogenicity of a replication-defective adenovirus type 5 HIV vaccine in Ad5-seronegative persons: a randomized clinical trial (HVTN 054).
PloS one 2010;5(10):e13579.
2010: Andrew J McMichael; Persephone Borrow; Georgia D Tomaras; Nilu Goonetilleke; Barton F Haynes
The immune response during acute HIV-1 infection: clues for vaccine development.
Nature reviews. Immunology 2010;10(1):11-23.
2009: Feng Gao; Richard M Scearce; S Munir Alam; Bhavna Hora; Shimao Xia; Julie E Hohm; Robert J Parks; Damon F Ogburn; Georgia D Tomaras; Emily Park; Woodrow E Lomas; Vernon C Maino; Susan A Fiscus; Myron S Cohen; M Anthony Moody; Beatrice H Hahn; Bette T Korber; Hua-Xin Liao; Barton F Haynes
Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins.
Virology 2009;394(1):91-8.
2009: Georgia D Tomaras; Barton F Haynes
HIV-1-specific antibody responses during acute and chronic HIV-1 infection.
Current opinion in HIV and AIDS 2009;4(5):373-9.
2009: Elin S Gray; Natasha Taylor; Diane Wycuff; Penny L Moore; Georgia D Tomaras; Constantinos Kurt Wibmer; Adrian Puren; Allan DeCamp; Peter B Gilbert; Blake Wood; David C Montefiori; James M Binley; George M Shaw; Barton F Haynes; John R Mascola; Lynn Morris
Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors.
Journal of virology 2009;83(17):8925-37.
2009: Mattia Bonsignori; M Anthony Moody; Robert J Parks; T Matt Holl; Garnett Kelsoe; Charles B Hicks; Nathan Vandergrift; Georgia D Tomaras; Barton F Haynes
HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2708-17.
2009: Marc C Levesque; M Anthony Moody; Kwan-Ki Hwang; Dawn J Marshall; John F Whitesides; Joshua D Amos; Thaddeus C Gurley; Sallie Allgood; Benjamin B Haynes; Nathan A Vandergrift; Steven Plonk; Daniel C Parker; Myron S Cohen; Georgia D Tomaras; Paul A Goepfert; George M Shaw; Joern schmitz; Joseph J Eron; Nicholas J Shaheen; Charles B Hicks; Hua-Xin Liao; Martin Markowitz; Garnett Kelsoe; David M Margolis; Barton F Haynes
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.
PLoS medicine 2009;6(7):e1000107.
2009: Olivier Lambotte; Guido Ferrari; Christiane Moog; Nicole L Yates; Hua-Xin Liao; Robert J Parks; Charles B Hicks; Kouros Owzar; Georgia D Tomaras; David C Montefiori; Barton F Haynes; Jean-François Delfraissy
Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers.
AIDS (London, England) 2009;23(8):897-906.
2009: Xiaoying Shen; Robert J Parks; David C Montefiori; Jennifer L Kirchherr; Brandon F Keele; Julie M Decker; William A Blattner; Feng Gao; Kent J Weinhold; Charles B Hicks; ML Greenberg; Beatrice H Hahn; George M Shaw; Barton F Haynes; Georgia D Tomaras
In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth.
Journal of virology 2009;83(8):3617-25.
2009: Heather B Miller; Kevin O Saunders; Georgia D Tomaras; Mariano A Garcia-Blanco
Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs.
PloS one 2009;4(5):e5710.
2008: Georgia D Tomaras; Nicole L Yates; Pinghuang Liu; Li Qin; Genevieve G Fouda; Leslie L Chavez; Allan C Decamp; Robert J Parks; Vicki C Ashley; Judith T Lucas; Myron Cohen; Joseph J Eron; Charles B Hicks; Hua-Xin Liao; Steven G Self; Gary Landucci; Donald N Forthal; Kent J Weinhold; Brandon F Keele; Beatrice H Hahn; ML Greenberg; Lynn Morris; Salim S Abdool Karim; William A Blattner; David C Montefiori; George M Shaw; Alan S Perelson; Barton F Haynes
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia.
Journal of virology 2008;82(24):12449-63.
2008: James M Binley; Elizabeth A Lybarger; Emma T Crooks; Michael S Seaman; Elin Gray; Katie L Davis; Julie M Decker; Diane Wycuff; Linda Harris; Natalie Hawkins; Blake Wood; Cory Nathe; Douglas Richman; Georgia D Tomaras; Frederic Bibollet-Ruche; James E Robinson; Lynn Morris; George M Shaw; David C Montefiori; John R Mascola
Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.
Journal of virology 2008;82(23):11651-68.
2008: Ana Paula Sales; Georgia D Tomaras; Thomas B Kepler
Improving peptide-MHC class I binding prediction for unbalanced datasets.
BMC bioinformatics 2008;9():385.
2008: S Munir Alam; Richard M Scearce; Robert J Parks; Kelly Plonk; Steven G Plonk; Laura L Sutherland; Miroslaw K Gorny; Susan Zolla-Pazner; Stacie Vanleeuwen; M Anthony Moody; Shi-Mao Xia; David C Montefiori; Georgia D Tomaras; Kent J Weinhold; Salim Abdool Karim; Charles B Hicks; Hua-Xin Liao; James Robinson; George M Shaw; Barton F Haynes
Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection.
Journal of virology 2008;82(1):115-25.
2007: Farley R Cleghorn; Jean W Pape; Mauro Schechter; Courtenay Bartholomew; Jorge Sanchez; Noreen Jack; Barbara J Metch; Marianne Hansen; Mary Allen; Huyen Cao; David C Montefiori; Georgia D Tomaras; Sanjay Gurunathan; Donna J Eastman; Regina F do Lago; Sonic Jean; Javier R Lama; Dale N Lawrence; Peter F Wright
Lessons from a multisite international trial in the Caribbean and South America of an HIV-1 Canarypox vaccine (ALVAC-HIV vCP1452) with or without boosting with MN rgp120.
Journal of acquired immune deficiency syndromes (1999) 2007;46(2):222-30.
2007: Nina D Russell; Barney S Graham; Michael C Keefer; M Juliana McElrath; Steven G Self; Kent J Weinhold; David C Montefiori; Guido Ferrari; Helen Horton; Georgia D Tomaras; Sanjay Gurunathan; Lynn Baglyos; Sharon E Frey; Mark MULLIGAN; Clayton D Harro; Susan P Buchbinder; Lindsey R Baden; William A Blattner; Beryl A Koblin; Lawrence Corey
Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.
Journal of acquired immune deficiency syndromes (1999) 2007;44(2):203-12.
2007: Paul A Goepfert; Georgia D Tomaras; Helen Horton; David Montefiori; Guido Ferrari; Mark Deers; Gerald Voss; Marguerite Koutsoukos; Louise Pedneault; Pierre Vandepapeliere; M Juliana McElrath; Paul Spearman; Jonathan D Fuchs; Beryl A Koblin; William A Blattner; Sharon Frey; Lindsey R Baden; Clayton D Harro; Thomas Evans
Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers.
Vaccine 2007;25(3):510-8.
2007: R Glenn Overman; Anthony L Llorens; ML Greenberg; Mariano A Garcia-Blanco; Georgia D Tomaras
Initiation of human immunodeficiency virus type 1 (HIV-1) transcription is inhibited by noncytolytic CD8 suppression.
The open virology journal 2007;1():1-7.
2006: Elizabeth J McFarland; Daniel C Johnson; Petronella Muresan; Terence Fenton; Georgia D Tomaras; James McNamara; Jennifer S Read; Steven D Douglas; Jaime G Deville; Marc Gurwith; Sanjay Gurunathan; John S Lambert
HIV-1 vaccine induced immune responses in newborns of HIV-1 infected mothers.
AIDS (London, England) 2006;20(11):1481-9.
2005: Daniel C Johnson; Elizabeth J McFarland; Petronella Muresan; Terence Fenton; James McNamara; Jennifer S Read; Elizabeth Hawkins; Pamela L Bouquin; Scharla Estep; Georgia D Tomaras; Carol A Vincent; Mobeen H Rathore; Ann J Melvin; Sanjay Gurunathan; John Lambert
Safety and immunogenicity of an HIV-1 recombinant canarypox vaccine in newborns and infants of HIV-1-infected women.
The Journal of infectious diseases 2005;192(12):2129-33.
2005: Paul A Goepfert; Helen Horton; M Juliana McElrath; Sanjay Gurunathan; Guido Ferrari; Georgia D Tomaras; David C Montefiori; Mary Allen; Ya-Lin Chiu; Paul Spearman; Jonathan D Fuchs; Beryl A Koblin; William A Blattner; Sharon Frey; Michael C Keefer; Lindsey R Baden; Lawrence Corey
High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects.
The Journal of infectious diseases 2005;192(7):1249-59.
2005: Michael R Betts; Barbara Exley; David A Price; Anju Bansal; Zenaido Tres Camacho; Vanessa Teaberry; Sadie M West; David R Ambrozak; Georgia D Tomaras; Mario Roederer; J. Michael Kilby; Jim Tartaglia; Robert B Belshe; Feng Gao; Daniel C Douek; Kent J Weinhold; Richard A Koup; Paul A Goepfert; Guido Ferrari
Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4512-7.
2005: Susan S Kaplan; Guido Ferrari; Terri Wrin; Nicholas S Hellmann; Georgia D Tomaras; Victoria E Gryszowka; Susan A Fiscus; Kent J Weinhold; Charles B Hicks
Longitudinal assessment of immune response and viral characteristics in HIV-infected patients with prolonged CD4(+)/viral load discordance.
AIDS research and human retroviruses 2005;21(1):13-6.
2004: William A Blattner; Kris Ann K Kwiterovic Oursler; Farley R Cleghorn; Man E Charurat; Anne M Sill; Courtenay Bartholomew; Noreen Jack; Thomas O'Brien; Jeffrey Edwards; Georgia D Tomaras; Kent J Weinhold; Michael Greenberg
Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDS.
The Journal of infectious diseases 2004;189(10):1793-801.
2003: Susan A Sufka; Guido Ferrari; Victoria E Gryszowka; Terri Wrin; Susan A Fiscus; Georgia D Tomaras; Herman F Staats; Dhavalkumar D Patel; Gregory D Sempowski; Nicholas S Hellmann; Kent J Weinhold; Charles B Hicks
Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control.
The Journal of infectious diseases 2003;187(7):1027-37.
2001: Georgia D Tomaras; ML Greenberg
CD8+ T cell mediated noncytolytic inhibition of human immunodeficiency virus type I.
Frontiers in bioscience : a journal and virtual library 2001;6():D575-98.
2000: Georgia D Tomaras; SF Lacey; CB McDanal; Guido Ferrari; Kent J Weinhold; ML Greenberg
CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3503-8.