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James Tomasek

Research Profile

Anatomy

Chemicals & Drugs

Disorders

Dupuytren's Contracture

Living Beings

Phenomena

Physiology

Wound Healing

Procedures

Immunohistochemistry

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Publications

TOP 3
James J Tomasek; Robert J Schwartz; Carol J Haaksma; Eric W Howard
Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition.
Eric W Howard; Eileen E Parks; David M Sherry; Elizabeth C Bullen; Beverly J Crider; Carol J Haaksma; Dawn L Updike; James J Tomasek
MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype.
Beverly J Crider; Carol J Haaksma; Eric W Howard; George M Risinger; James J Tomasek
Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.

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All Publications

2013: James J Tomasek; Robert J Schwartz; Carol J Haaksma; Eric W Howard
Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2013;21(1):166-76.
2012: Eric W Howard; Eileen E Parks; David M Sherry; Elizabeth C Bullen; Beverly J Crider; Carol J Haaksma; Dawn L Updike; James J Tomasek
MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype.
Experimental cell research 2012;318(13):1542-53.
2011: Beverly J Crider; Carol J Haaksma; Eric W Howard; George M Risinger; James J Tomasek
Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.
The Journal of investigative dermatology 2011;131(12):2378-85.
2011: Carol J Haaksma; Robert J Schwartz; James J Tomasek
Myoepithelial cell contraction and milk ejection are impaired in mammary glands of mice lacking smooth muscle alpha-actin.
Biology of reproduction 2011;85(1):13-21.
2010: George M Risinger; Dawn L Updike; Elizabeth C Bullen; James J Tomasek; Eric W Howard
TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB.
American journal of physiology. Cell physiology 2010;298(1):C191-201.
2006: James J Tomasek; Carol J Haaksma; Robert J Schwartz; Duc T Vuong; Sarah X Zhang; John D Ash; Jian-Xing Ma; Muayyad R Al-Ubaidi
Deletion of smooth muscle alpha-actin alters blood-retina barrier permeability and retinal function.
Investigative ophthalmology & visual science 2006;47(6):2693-700.
2006: James J Tomasek; Melville B Vaughan; Bradley P Kropp; Giulio Gabbiani; Michael D Martin; Carol J Haaksma; Boris Hinz
Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(3):313-20.
2006: Randle M Gallucci; Eric G Lee; James J Tomasek
IL-6 modulates alpha-smooth muscle actin expression in dermal fibroblasts from IL-6-deficient mice.
The Journal of investigative dermatology 2006;126(3):561-8.
2005: James J Tomasek; Joel McRae; Gary K Owens; Carol J Haaksma
Regulation of alpha-smooth muscle actin expression in granulation tissue myofibroblasts is dependent on the intronic CArG element and the transforming growth factor-beta1 control element.
The American journal of pathology 2005;166(5):1343-51.
2004: R A Zimmerman; James J Tomasek; J McRae; Carol J Haaksma; R J Schwartz; Hsueh-Kung Lin; R L Cowan; A N Jones; Bradley P Kropp
Decreased expression of smooth muscle alpha-actin results in decreased contractile function of the mouse bladder.
The Journal of urology 2004;172(4 Pt 2):1667-72.
2004: Ursula Mirastschijski; Carol J Haaksma; James J Tomasek; Magnus Ågren
Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds.
Experimental cell research 2004;299(2):465-75.
2004: Hsueh-Kung Lin; Rick Cowan; Pete Moore; Yuanyuan Zhang; Qing Yang; John A Peterson; James J Tomasek; Bradley P Kropp; Earl Y Cheng
Characterization of neuropathic bladder smooth muscle cells in culture.
The Journal of urology 2004;171(3):1348-52.
2002: James J Tomasek; Giulio Gabbiani; Boris Hinz; Christine Chaponnier; Robert A Brown
Myofibroblasts and mechano-regulation of connective tissue remodelling.
Nature reviews. Molecular cell biology 2002;3(5):349-63.
2001: Boris Hinz; G Celetta; James J Tomasek; Giulio Gabbiani; Christine Chaponnier
Alpha-smooth muscle actin expression upregulates fibroblast contractile activity.
Molecular biology of the cell 2001;12(9):2730-41.
2001: Lea M Spyres; Maen Qa'Dan; A Meader; James J Tomasek; Eric W Howard; Jimmy D Ballard
Cytosolic delivery and characterization of the TcdB glucosylating domain by using a heterologous protein fusion.
Infection and immunity 2001;69(1):599-601.
2000: Melville B Vaughan; Eric W Howard; James J Tomasek
Transforming growth factor-beta1 promotes the morphological and functional differentiation of the myofibroblast.
Experimental cell research 2000;257(1):180-9.
2000: M Parizi; Eric W Howard; James J Tomasek
Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase.
Experimental cell research 2000;254(2):210-20.
2000: Ghazi M Rayan; Carol J Haaksma; James J Tomasek; Kevin J Mccarthy
Basement membrane chondroitin sulfate proteoglycan and vascularization of the developing mammalian limb bud.
The Journal of hand surgery 2000;25(1):150-8.
1999: Bradley P Kropp; Yuanyuan Zhang; James J Tomasek; Rick Cowan; Peter D Furness; Melville B Vaughan; M Parizi; Earl Y Cheng
Characterization of cultured bladder smooth muscle cells: assessment of in vitro contractility.
The Journal of urology 1999;162(5):1779-84.
1999: Ghazi M Rayan; M P Abercrombie; Thomas F Linsenmayer; J M Fitch; James J Tomasek
Distribution of type IV collagen during avian limb bud development.
The Journal of hand surgery 1999;24(3):619-27.
1999: James J Tomasek; Melville B Vaughan; Carol J Haaksma
Cellular structure and biology of Dupuytren's disease.
Hand clinics 1999;15(1):21-34.
1997: TK Vu; R W Liu; Carol J Haaksma; James J Tomasek; Eric W Howard
Identification and cloning of the membrane-associated serine protease, hepsin, from mouse preimplantation embryos.
The Journal of biological chemistry 1997;272(50):31315-20.
1997: Z Porpaczy; James J Tomasek; Dale A Freeman
Internalized plasma membrane cholesterol passes through an endosome compartment that is distinct from the acid vesicle-lysosome compartment.
Experimental cell research 1997;234(2):217-24.
1997: James J Tomasek; N L Halliday; Dawn L Updike; J S Ahern-Moore; TK Vu; R W Liu; Eric W Howard
Gelatinase A activation is regulated by the organization of the polymerized actin cytoskeleton.
The Journal of biological chemistry 1997;272(11):7482-7.
1996: Ghazi M Rayan; M Parizi; James J Tomasek
Pharmacologic regulation of Dupuytren's fibroblast contraction in vitro.
The Journal of hand surgery 1996;21(6):1065-70.
1996: Eric W Howard; R Benton; J Ahern-Moore; James J Tomasek
Cellular contraction of collagen lattices is inhibited by nonenzymatic glycation.
Experimental cell research 1996;228(1):132-7.
1995: B K Pilcher; N S Levine; James J Tomasek
Thrombin promotion of isometric contraction in fibroblasts: its extracellular mechanism of action.
Plastic and reconstructive surgery 1995;96(5):1188-95.
1995: James J Tomasek; Ghazi M Rayan
Correlation of alpha-smooth muscle actin expression and contraction in Dupuytren's disease fibroblasts.
The Journal of hand surgery 1995;20(3):450-5.
1995: N L Halliday; James J Tomasek
Mechanical properties of the extracellular matrix influence fibronectin fibril assembly in vitro.
Experimental cell research 1995;217(1):109-17.
1995: P D Inhofe; W A Grana; D Egle; K W Min; James J Tomasek
The effects of anabolic steroids on rat tendon. An ultrastructural, biomechanical, and biochemical analysis.
The American journal of sports medicine 1995;23(2):227-32.
1994: Ghazi M Rayan; James J Tomasek
Generation of contractile force by cultured Dupuytren's disease and normal palmar fibroblasts.
Tissue & cell 1994;26(5):747-56.
1994: N L Halliday; Ghazi M Rayan; L Zardi; James J Tomasek
Distribution of ED-A and ED-B containing fibronectin isoforms in Dupuytren's disease.
The Journal of hand surgery 1994;19(3):428-34.
1994: B K Pilcher; D W Kim; D H Carney; James J Tomasek
Thrombin stimulates fibroblast-mediated collagen lattice contraction by its proteolytically activated receptor.
Experimental cell research 1994;211(2):368-73.
1994: James J Tomasek; S W Meyers; J B Basinger; D T Green; R L Shew
Diabetic and age-related enhancement of collagen-linked fluorescence in cortical bones of rats.
Life sciences 1994;55(11):855-61.
1992: James J Tomasek; S K Akiyama
Fibroblast-mediated collagen gel contraction does not require fibronectin-alpha 5 beta 1 integrin interaction.
The Anatomical record 1992;234(2):153-60.
1992: James J Tomasek; Carol J Haaksma; Robert Eddy; Melville B Vaughan
Fibroblast contraction occurs on release of tension in attached collagen lattices: dependency on an organized actin cytoskeleton and serum.
The Anatomical record 1992;232(3):359-68.
1991: James J Tomasek; Carol J Haaksma
Fibronectin filaments and actin microfilaments are organized into a fibronexus in Dupuytren's diseased tissue.
The Anatomical record 1991;230(2):175-82.
1988: M P Abercrombie; James J Tomasek
Effects of enzyme isolation on the basal lamina of developing avian limb bud epithelia.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1988;24(8):803-10.
1988: Robert Eddy; J A Petro; James J Tomasek
Evidence for the nonmuscle nature of the "myofibroblast" of granulation tissue and hypertropic scar. An immunofluorescence study.
The American journal of pathology 1988;130(2):252-60.
1987: James J Tomasek; R J Schultz; Carol J Haaksma
Extracellular matrix-cytoskeletal connections at the surface of the specialized contractile fibroblast (myofibroblast) in Dupuytren disease.
The Journal of bone and joint surgery. American volume 1987;69(9):1400-7.
1986: James J Tomasek; R J Schultz; C W Episalla; S A Newman
The cytoskeleton and extracellular matrix of the Dupuytren's disease "myofibroblast": an immunofluorescence study of a nonmuscle cell type.
The Journal of hand surgery 1986;11(3):365-71.