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Vittorio Tomasi

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Cristiana Griffoni; Serena Di Molfetta; Luca Fantozzi; Cristiana Zanetti; Proto Pippia; Vittorio Tomasi; Enzo Spisni
Modification of proteins secreted by endothelial cells during modeled low gravity exposure.
Antonio Strillacci; Cristiana Griffoni; G Lazzarini; M C Valerii; S Di Molfetta; Fernando Rizzello; Massimo Campieri; M P Moyer; Vittorio Tomasi; Enzo Spisni
Selective cyclooxygenase-2 silencing mediated by engineered E. coli and RNA interference induces anti-tumour effects in human colon cancer cells.
Vittorio Tomasi
Signal transduction in neurons: effects of cellular prion protein on fyn kinase and ERK1/2 kinase.

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All Publications

2011: Cristiana Griffoni; Serena Di Molfetta; Luca Fantozzi; Cristiana Zanetti; Proto Pippia; Vittorio Tomasi; Enzo Spisni
Modification of proteins secreted by endothelial cells during modeled low gravity exposure.
Journal of cellular biochemistry 2011;112(1):265-72.
2010: Antonio Strillacci; Cristiana Griffoni; G Lazzarini; M C Valerii; S Di Molfetta; Fernando Rizzello; Massimo Campieri; M P Moyer; Vittorio Tomasi; Enzo Spisni
Selective cyclooxygenase-2 silencing mediated by engineered E. coli and RNA interference induces anti-tumour effects in human colon cancer cells.
British journal of cancer 2010;103(7):975-86.
2010: Vittorio Tomasi
Signal transduction in neurons: effects of cellular prion protein on fyn kinase and ERK1/2 kinase.
Immunity & ageing : I & A 2010;7 Suppl 1():S5.
2010: Antonio Strillacci; Cristiana Griffoni; Maria Chiara Valerii; Giorgia Lazzarini; Vittorio Tomasi; Enzo Spisni
RNAi-based strategies for cyclooxygenase-2 inhibition in cancer.
Journal of biomedicine & biotechnology 2010;2010():828045.
2009: Enzo Spisni; Maria Chiara Valerii; Marcella Manerba; Antonio Strillacci; Elisabetta Polazzi; Toni Mattia; Cristiana Griffoni; Vittorio Tomasi
Effect of copper on extracellular levels of key pro-inflammatory molecules in hypothalamic GN11 and primary neurons.
Neurotoxicology 2009;30(4):605-12.
2009: Antonio Strillacci; Cristiana Griffoni; Pasquale Sansone; Paola Paterini; Giulia Piazzi; Giorgia Lazzarini; Enzo Spisni; Maria Abbondanza Pantaleo; Guido Biasco; Vittorio Tomasi
MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells.
Experimental cell research 2009;315(8):1439-47.
2008: Simona Tavolari; Massimiliano Bonafè; Marina Marini; Carla Ferreri; G Bartolini; Elisa Brighenti; Sonia Manara; Vittorio Tomasi; Stefan Laufer; Tiziana Guarnieri
Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
Carcinogenesis 2008;29(2):371-80.
2007: Cristiana Griffoni; Enzo Spisni; Antonio Strillacci; Mattia Toni; Markus Michael Bachschmid; Vittorio Tomasi
Selective inhibition of prostacyclin synthase activity by rofecoxib.
Journal of cellular and molecular medicine 2007;11(2):327-38.
2006: Antonio Strillacci; Cristiana Griffoni; Enzo Spisni; Maria Cristina Manara; Vittorio Tomasi
RNA interference as a key to knockdown overexpressed cyclooxygenase-2 gene in tumour cells.
British journal of cancer 2006;94(9):1300-10.
2006: Simona Tavolari; Laura Bucci; Vittorio Tomasi; Tiziana Guarnieri
Selected polychlorobiphenyls congeners bind to estrogen receptor alpha in human umbilical vascular endothelial (HUVE) cells modulating angiogenesis.
Toxicology 2006;218(1):67-74.
2006: Mattia Toni; Enzo Spisni; Cristiana Griffoni; Spartaco Santi; Massimo Riccio; Patrizia Lenaz; Vittorio Tomasi
Cellular prion protein and caveolin-1 interaction in a neuronal cell line precedes Fyn/Erk 1/2 signal transduction.
Journal of biomedicine & biotechnology 2006;2006(5):69469.
2006: Enzo Spisni; Mattia Toni; Antonio Strillacci; Grazia Galleri; Spartaco Santi; Cristiana Griffoni; Vittorio Tomasi
Caveolae and caveolae constituents in mechanosensing: effect of modeled microgravity on cultured human endothelial cells.
Cell biochemistry and biophysics 2006;46(2):155-64.
2005: Enzo Spisni; Vittorio Tomasi; Alessandro Cestaro; Silvio C E Tosatto
Structural insights into the function of human caveolin 1.
Biochemical and biophysical research communications 2005;338(3):1383-90.
2005: Mattia Toni; Maria Lina Massimino; Cristiana Griffoni; Benedetto Salvato; Vittorio Tomasi; Enzo Spisni
Extracellular copper ions regulate cellular prion protein (PrPC) expression and metabolism in neuronal cells.
FEBS letters 2005;579(3):741-4.
2005: Filippo Acconcia; Paolo Ascenzi; Alessio Bocedi; Enzo Spisni; Vittorio Tomasi; Anna Trentalance; Paolo Visca; Maria Marino
Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol.
Molecular biology of the cell 2005;16(1):231-7.
2004: Pavel P Laktionov; Elena Y Rykova; Mattia Toni; Enzo Spisni; Cristiana Griffoni; Anton Bryksin; Natalia Volodko; Valentin Vlassov; Vittorio Tomasi
Knock down of cytosolic phospholipase A2: an antisense oligonucleotide having a nuclear localization binds a C-terminal motif of glyceraldehyde-3-phosphate dehydrogenase.
Biochimica et biophysica acta 2004;1636(2-3):129-35.
2003: Enzo Spisni; Maria Cristina Bianco; Cristiana Griffoni; Mattia Toni; Romina D'Angelo; Spartaco Santi; Massimo Riccio; Vittorio Tomasi
Mechanosensing role of caveolae and caveolar constituents in human endothelial cells.
Journal of cellular physiology 2003;197(2):198-204.
2003: Cristiana Griffoni; Mattia Toni; Enzo Spisni; Maria Cristina Bianco; Spartaco Santi; Massimo Riccio; Vittorio Tomasi
The cellular prion protein: biochemistry, topology, and physiologic functions.
Cell biochemistry and biophysics 2003;38(3):287-304.
2002: Enzo Spisni; Maria Cristina Bianco; Francesca Blasi; Spartaco Santi; Massimo Riccio; Mattia Toni; Cristiana Griffoni; Vittorio Tomasi
Hypergravity impairs angiogenic response of in vitro cultured human primary endothelial cells.
Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology 2002;9(1):P285-6.
2002: Spartaco Santi; Maria Cristina Bianco; Francesca Blasi; Enzo Spisni; Massimo Riccio; Mattia Toni; Cristiana Griffoni; Vittorio Tomasi
Hypergravity affects cell cycle progression and caveolin-1 expression of in vitro cultured human primary endothelial cells.
Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology 2002;9(1):P283-4.
2002: Maria Lina Massimino; Cristiana Griffoni; Enzo Spisni; Mattia Toni; Vittorio Tomasi
Involvement of caveolae and caveolae-like domains in signalling, cell survival and angiogenesis.
Cellular signalling 2002;14(2):93-8.
2001: Enzo Spisni; Cristiana Griffoni; Spartaco Santi; Massimo Riccio; R Marulli; G Bartolini; Mattia Toni; V Ullrich; Vittorio Tomasi
Colocalization prostacyclin (PGI2) synthase--caveolin-1 in endothelial cells and new roles for PGI2 in angiogenesis.
Experimental cell research 2001;266(1):31-43.
2001: Vittorio Tomasi; Pavel P Laktionov; Anton Bryksin; N V Volod'ko; Cristiana Griffoni; Elena Y Rykova; Enzo Spisni; R Kraft; Valentin V Vlassov
Glyceraldehyde-3-phosphate dehydrogenase is responsible for intranuclear localization of some oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):863-7.
2001: Cristiana Griffoni; Pavel P Laktionov; Elena Y Rykova; Enzo Spisni; Massimo Riccio; Spartaco Santi; Anton Bryksin; N Volodko; R Kraft; Valentin Vlassov; Vittorio Tomasi
The Rossmann fold of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a nuclear docking site for antisense oligonucleotides containing a TAAAT motif.
Biochimica et biophysica acta 2001;1530(1):32-46.
2000: Cristiana Griffoni; Enzo Spisni; Spartaco Santi; Massimo Riccio; Tiziana Guarnieri; Vittorio Tomasi
Knockdown of caveolin-1 by antisense oligonucleotides impairs angiogenesis in vitro and in vivo.
Biochemical and biophysical research communications 2000;276(2):756-61.
1999: Cristiana Griffoni; Enzo Spisni; M Orlandi; Spartaco Santi; Massimo Riccio; Vittorio Tomasi
A 38 kDa nuclear protein is involved in the retention of an antisense oligonucleotide directed against cytosolic phospholipase A2.
Nucleosides & nucleotides 1999;18(6-7):1673-6.
1998: Vittorio Tomasi; Enzo Spisni; Cristiana Griffoni; Spartaco Santi
Nuclear targeting of antisense oligonucleotides: modification of PRE-mRNA splicing or inhibition of polyadenylation?
Nucleosides & nucleotides 1998;(9-11):2073-80.
1998: Enzo Spisni; M Cavazzoni; Cristiana Griffoni; E Calzolari; Vittorio Tomasi
Evidence that photodynamic stress kills Zellweger fibroblasts by a nonapoptotic mechanism.
Biochimica et biophysica acta 1998;1402(1):61-9.
1995: Enzo Spisni; G Bartolini; M Orlandi; B Belletti; Spartaco Santi; Vittorio Tomasi
Prostacyclin (PGI2) synthase is a constitutively expressed enzyme in human endothelial cells.
Experimental cell research 1995;219(2):507-13.
1995: G Bartolini; M Orlandi; Enzo Spisni; J Davis; L Minghetti; B Belletti; Mariella Chiricolo; Vittorio Tomasi
Possible involvement of prostaglandin H synthase-1 induction in the differentiation of U-937 cells.
BioFactors (Oxford, England) 1995;5(1):11-8.
1995: B Belletti; Enzo Spisni; G Bartolini; M Orlandi; Vittorio Tomasi
Post-transcriptional regulation of thromboxane A2 synthase in U937 cells.
Biochemical and biophysical research communications 1995;209(3):901-6.
1994: M Orlandi; G Bartolini; B Belletti; Enzo Spisni; Vittorio Tomasi
Thromboxane A2 synthase activity in platelet free human monocytes.
Biochimica et biophysica acta 1994;1215(3):285-90.
1992: Enzo Spisni; F Manica; Vittorio Tomasi
Involvement of prostanoids in the regulation of angiogenesis by polypeptide growth factors.
Prostaglandins, leukotrienes, and essential fatty acids 1992;47(2):111-5.
1990: G Bartolini; M Orlandi; Mariella Chiricolo; Federico Licastro; Paolo Zambonelli; L Minghetti; Vittorio Tomasi
Interleukins and interferons: yin-yang modulators of PGH synthase in human macrophages.
BioFactors (Oxford, England) 1990;2(4):267-70.
1990: Vittorio Tomasi; F Manica; Enzo Spisni
Polypeptide growth factors and angiogenesis.
BioFactors (Oxford, England) 1990;2(4):213-7.
1990: Claudio Franceschi; G Bartolini; M Orlandi; L Minghetti; Federico Licastro; Mariella Chiricolo; Vittorio Tomasi
Prostanoids as second messengers of polypeptide growth factors.
Agents and actions 1990;29(1-2):39-47.
1989: Mariella Chiricolo; Marco Lenzi; F Bianchi; Claudio Franceschi; G Bartolini; M Orlandi; Vittorio Tomasi; Federico Licastro
Immune dysfunction in primary biliary cirrhosis. II. Increased production of prostaglandin E.
Scandinavian journal of immunology 1989;30(3):363-7.
1989: M Orlandi; G Bartolini; L Minghetti; S Luchetti; B Giuliucci; Mariella Chiricolo; Vittorio Tomasi
Prostaglandin and thromboxane biosynthesis in isolated platelet-free human monocytes. III. The induction of cycloxygenase by colony stimulating factor-1.
Prostaglandins, leukotrienes, and essential fatty acids 1989;36(2):101-6.
1989: Luigi Fiume; Mariella Chiricolo; Corrado Busi; Alessandro Mattioli; C Spinelli; G Spinosa; G Bartolini; L Minghetti; M Orlandi; Vittorio Tomasi
A conjugate of prednisolone with albumin is pharmacologically active in macrophages.
Pharmaceutica acta Helvetiae 1989;64(12):351-2.
1988: L Minghetti; G Bartolini; M Orlandi; Mariella Chiricolo; Federico Licastro; Claudio Franceschi; Vittorio Tomasi
Purification and partial characterization of serum monocytotropic factor, a platelet-derived cyclooxygenase-inducing polypeptide.
Biochimica et biophysica acta 1988;958(3):315-22.
1986: G Bartolini; M Orlandi; Mariella Chiricolo; L Minghetti; F Guerrini; M Fidan; Claudio Franceschi; Vittorio Tomasi
Regulation of thromboxane A2 biosynthesis in platelet-free human monocytes and the possible role of polypeptide growth factor(s) in the induction of cyclooxygenase system.
Biochimica et biophysica acta 1986;876(3):486-93.
1986: Vittorio Tomasi; A Strano; M Orlandi; G Bartolini; Giovanni Davì; D Monti; U Taddeo; G Zavagli
Are the vascular complications of diabetes mellitus preceded by an altered thromboxane/prostacyclin plasmatic ratio?
Medical hypotheses 1986;19(3):229-41.
1986: Mariella Chiricolo; G Bartolini; M Orlandi; G Peta; M Corneli; M Spinosa; Vittorio Tomasi; Claudio Franceschi
Prostaglandin and thromboxane biosynthesis in resting and activated platelet-free monocytes from aged subjects.
Gerontology 1986;32(2):69-73.
1985: G Zavagli; U Taddeo; G Bolelli; M Orlandi; G Bartolini; Vittorio Tomasi
Platelet aggregation and evaluation of the ratio thromboxane B2/6-keto-prostaglandin F1 alpha in the plasma of patients on long term cimetidine treatment.
Prostaglandins, leukotrienes, and medicine 1985;19(3):241-50.
1985: M Orlandi; G Bartolini; Mariella Chiricolo; L Minghetti; Claudio Franceschi; Vittorio Tomasi
Prostaglandin and thromboxane biosynthesis in isolated platelet-free human monocytes. I. A modified procedure for the characterization of the prostaglandin spectrum produced by resting and activated monocytes.
Prostaglandins, leukotrienes, and medicine 1985;18(2):205-16.
1985: R Mastacchi; G Bartolini; M Orlandi; Mariella Chiricolo; F Guerrini; Claudio Franceschi; Vittorio Tomasi
Prostaglandins and cyclic nucleotides as effectors in non-lymphocyte mediated surveillance processes ( short review).
Anticancer research 1985;5(2):167-70.
1985: Claudio Franceschi; Mariella Chiricolo; Federico Licastro; M Orlandi; G Bartolini; Vittorio Tomasi
[Is it useful to correct the immunological deficit in cancer patients? And with what modality?].
La Ricerca in clinica e in laboratorio 1985;15 Suppl 2():45-59.
1984: Vittorio Tomasi; M Orlandi; G Bartolini
Mechanism of action and biological significance of prostaglandins and leukotrienes.
Bollettino della Società italiana di biologia sperimentale 1984;60 Suppl 4():105-9.
1984: G Bartolini; Vittorio Tomasi; M Orlandi
The effect of prostaglandins on cyclic AMP levels of human peripheral lymphocytes and rat thymocytes.
Bollettino della Società italiana di biologia sperimentale 1984;60 Suppl 4():99-104.
1983: M Orlandi; Giovanni Davì; G Triolo; Vittorio Tomasi; A Strano
Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes.
Prostaglandins, leukotrienes, and medicine 1983;12(4):437-8.
1983: Giovanni Davì; M Orlandi; F Picone; G Galione; C Meringolo; A Mazzola; Vittorio Tomasi; G Capodicasa; A Strano
Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients.
Prostaglandins, leukotrienes, and medicine 1983;10(3):309-17.
1980: R Mastacchi; S Fadda; Vittorio Tomasi; O Barnabei
The effect of 6-keto-prostaglandin E1 on human lymphocyte cAMP levels.
Prostaglandins and medicine 1980;5(6):487-94.
1980: S Fadda; R Mastacchi; G Romeo; Vittorio Tomasi; O Barnabei
Regulation of cyclic AMP levels in human lymphocytes and lymphoblasts by prostaglandins.
Prostaglandins and medicine 1980;5(6):477-86.