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Yaron Tomer

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TOP 3
Yaron Tomer; Erlinda Concepcion; Terry F Davies; Alia Hasham; Mehdi Keddache; Mihaela Stefan; David A Greenberg
Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes.
Alia Hasham; Yaron Tomer
Genetic and epigenetic mechanisms in thyroid autoimmunity.
Amanda K Huber; Eric Jacobson; Mehdi Keddache; Rauf Latif; Cheuk Wun Li; Eric Smith; Erlinda Concepcion; Fred D Finkelman; Weijia Zhang; Yaron Tomer
Genetically driven target tissue overexpression of CD40: a novel mechanism in autoimmune disease.

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All Publications

2013: Yaron Tomer; Erlinda Concepcion; Terry F Davies; Alia Hasham; Mehdi Keddache; Mihaela Stefan; David A Greenberg
Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes.
The Journal of clinical endocrinology and metabolism 2013;98(1):E144-52.
2012: Alia Hasham; Yaron Tomer
Genetic and epigenetic mechanisms in thyroid autoimmunity.
Immunologic research 2012;54(1-3):204-13.
2012: Amanda K Huber; Eric Jacobson; Mehdi Keddache; Rauf Latif; Cheuk Wun Li; Eric Smith; Erlinda Concepcion; Fred D Finkelman; Weijia Zhang; Yaron Tomer
Genetically driven target tissue overexpression of CD40: a novel mechanism in autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(6):3043-53.
2012: Alessia L Carluccio; Nina K Sundaram; Robert T Yanagisawa; Yaron Tomer
Apathetic thyrotoxicosis secondary to atypical subacute thyroiditis.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2012;18(5):e127-9.
2011: Deirdre Cocks Eschler; Alia Hasham; Yaron Tomer
Cutting edge: the etiology of autoimmune thyroid diseases.
Clinical reviews in allergy & immunology 2011;41(2):190-7.
2011: Mihaela Stefan; Erlinda Conception; Mohammed Fadlalla; David A Greenberg; Kenneth Ho; Amanda K Huber; Eric M Jacobson; Cheuk Wun Li; Luce Skrabanek; Yaron Tomer
Novel variant of thyroglobulin promoter triggers thyroid autoimmunity through an epigenetic interferon alpha-modulated mechanism.
The Journal of biological chemistry 2011;286(36):31168-79.
2011: Alia Hasham; Yaron Tomer
The recent rise in the frequency of type 1 diabetes: who pulled the trigger?
Journal of autoimmunity 2011;37(1):1-2.
2011: Nagako Akeno; Eric P Smith; Mihaela Stefan; Amanda K Huber; Weijia Zhang; Mehdi Keddache; Yaron Tomer
IFN-α mediates the development of autoimmunity both by direct tissue toxicity and through immune cell recruitment mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4693-706.
2011: Eric M Jacobson; Erlinda Concepcion; Kenneth Ho; Peter Kopp; Jussara Vono Toniolo; Yaron Tomer
cDNA immunization of mice with human thyroglobulin generates both humoral and T cell responses: a novel model of thyroid autoimmunity.
PloS one 2011;6(4):e19200.
2011: F Menconi; A Hasham; Yaron Tomer
Environmental triggers of thyroiditis: hepatitis C and interferon-α.
Journal of endocrinological investigation 2011;34(1):78-84.
2011: Amanda K Huber; Erlinda Concepcion; Alisha Gandhi; Francesca Menconi; Eric P Smith; Mehdi Keddache; Yaron Tomer
Analysis of immune regulatory genes' copy number variants in Graves' disease.
Thyroid : official journal of the American Thyroid Association 2011;21(1):69-74.
2010: Francesca Menconi; Roman Osman; Maria C Monti; David A Greenberg; Erlinda Concepcion; Yaron Tomer
Shared molecular amino acid signature in the HLA-DR peptide binding pocket predisposes to both autoimmune diabetes and thyroiditis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(39):16899-903.
2010: Francesca Menconi; Amanda Huber; Roman Osman; Erlinda Concepcion; Eric M Jacobson; Mihaela Stefan; Chela S David; Yaron Tomer
Tg.2098 is a major human thyroglobulin T-cell epitope.
Journal of autoimmunity 2010;35(1):45-51.
2010: Yaron Tomer
Genetic susceptibility to autoimmune thyroid disease: past, present, and future.
Thyroid : official journal of the American Thyroid Association 2010;20(7):715-25.
2010: Yaron Tomer; Virginia Sarapura; George J Kahaly
Thyroid disorders: it's very personal.
Thyroid : official journal of the American Thyroid Association 2010;20(7):677-9.
2010: Yaron Tomer
Hepatitis C and interferon induced thyroiditis.
Journal of autoimmunity 2010;34(3):J322-6.
2009: Yaron Tomer; Francesca Menconi
Interferon induced thyroiditis.
Best practice & research. Clinical endocrinology & metabolism 2009;23(6):703-12.
2009: Yaron Tomer; Amanda Huber
The etiology of autoimmune thyroid disease: a story of genes and environment.
Journal of autoimmunity 2009;32(3-4):231-9.
2009: Maria Justina B Villano; Amanda K Huber; David A Greenberg; Brian K Golden; Erlinda Concepcion; Yaron Tomer
Autoimmune thyroiditis and diabetes: dissecting the joint genetic susceptibility in a large cohort of multiplex families.
The Journal of clinical endocrinology and metabolism 2009;94(4):1458-66.
2008: Nagako Akeno; Jason T Blackard; Yaron Tomer
HCV E2 protein binds directly to thyroid cells and induces IL-8 production: a new mechanism for HCV induced thyroid autoimmunity.
Journal of autoimmunity 2008;31(4):339-44.
2008: Xiaoming Yin; Rauf Latif; Rebecca Bahn; Yaron Tomer; Terry F Davies
Influence of the TSH receptor gene on susceptibility to Graves' disease and Graves' ophthalmopathy.
Thyroid : official journal of the American Thyroid Association 2008;18(11):1201-6.
2008: Amanda Huber; Francesca Menconi; Sarah Dawn Corathers; Eric M Jacobson; Yaron Tomer
Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms.
Endocrine reviews 2008;29(6):697-725.
2008: Francesca Menconi; Maria C Monti; David A Greenberg; Taiji Oashi; Roman Osman; terry Davies; Yoshiyuki Ban; Eric M Jacobson; Erlinda Concepcion; Cheuk Wun Li; Yaron Tomer
Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):14034-9.
2008: Yoshiyuki Ban; David A Greenberg; terry Davies; Eric Jacobson; Erlinda Concepcion; Yaron Tomer
'Linkage analysis of thyroid antibody production: evidence for shared susceptibility to clinical autoimmune thyroid disease.
The Journal of clinical endocrinology and metabolism 2008;93(9):3589-96.
2008: Amanda K Huber; Eric M Jacobson; Krystian Jazdzewski; Erlinda Concepcion; Yaron Tomer
Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.
The Journal of clinical endocrinology and metabolism 2008;93(3):1077-81.
2008: Eric M Jacobson; Amanda Huber; Yaron Tomer
The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology.
Journal of autoimmunity 2008;30(1-2):58-62.
2007: Yaron Tomer; Jason T Blackard; Nagako Akeno
Interferon alpha treatment and thyroid dysfunction.
Endocrinology and metabolism clinics of North America 2007;36(4):1051-66; x-xi.
2007: Eric M Jacobson; Yaron Tomer
The genetic basis of thyroid autoimmunity.
Thyroid : official journal of the American Thyroid Association 2007;17(10):949-61.
2007: Xiaoming Yin; Rauf Latif; Yaron Tomer; terry Davies
Thyroid epigenetics: X chromosome inactivation in patients with autoimmune thyroid disease.
Annals of the New York Academy of Sciences 2007;1110():193-200.
2007: Yaron Tomer; Francesca Menconi; terry Davies; Giuseppe Barbesino; Roberto Rocchi; Aldo Pinchera; Erlinda Concepcion; David A Greenberg
Dissecting genetic heterogeneity in autoimmune thyroid diseases by subset analysis.
Journal of autoimmunity 2007;29(2-3):69-77.
2007: Yoshio Ban; Teruaki Tozaki; Takashi Tobe; Yoshio Ban; Eric M Jacobson; Erlinda Concepcion; Yaron Tomer
The regulatory T cell gene FOXP3 and genetic susceptibility to thyroid autoimmunity: an association analysis in Caucasian and Japanese cohorts.
Journal of autoimmunity 2007;28(4):201-7.
2007: Eric M Jacobson; A K Huber; Nagako Akeno; M Sivak; C W Li; Erlinda Concepcion; K Ho; Yaron Tomer
A CD40 Kozak sequence polymorphism and susceptibility to antibody-mediated autoimmune conditions: the role of CD40 tissue-specific expression.
Genes and immunity 2007;8(3):205-14.
2007: Eric M Jacobson; Yaron Tomer
The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future.
Journal of autoimmunity 2007;28(2-3):85-98.
2006: Susan E Hodge; Yoshiyuki Ban; Lisa J Strug; David A Greenberg; terry Davies; Erlinda Concepcion; Ronald Villanueva; Yaron Tomer
Possible interaction between HLA-DRbeta1 and thyroglobulin variants in Graves' disease.
Thyroid : official journal of the American Thyroid Association 2006;16(4):351-5.
2006: Jamie C Mandac; Sonal Chaudhry; Kenneth E Sherman; Yaron Tomer
The clinical and physiological spectrum of interferon-alpha induced thyroiditis: toward a new classification.
Hepatology (Baltimore, Md.) 2006;43(4):661-72.
2005: Yoshiyuki Ban; Yaron Tomer
Genetic susceptibility in thyroid autoimmunity.
Pediatric endocrinology reviews : PER 2005;3(1):20-32.
2005: terry Davies; Takao Ando; Reigh-Yi Lin; Yaron Tomer; Rauf Latif
Thyrotropin receptor-associated diseases: from adenomata to Graves disease.
The Journal of clinical investigation 2005;115(8):1972-83.
2005: Brian Golden; Lara Levin; Yoshiyuki Ban; Erlinda Concepcion; David A Greenberg; Yaron Tomer
Genetic analysis of families with autoimmune diabetes and thyroiditis: evidence for common and unique genes.
The Journal of clinical endocrinology and metabolism 2005;90(8):4904-11.
2005: Eric M Jacobson; Erlinda Concepcion; Taiji Oashi; Yaron Tomer
A Graves' disease-associated Kozak sequence single-nucleotide polymorphism enhances the efficiency of CD40 gene translation: a case for translational pathophysiology.
Endocrinology 2005;146(6):2684-91.
2005: Yoshiyuki Ban; Yaron Tomer
Susceptibility genes in thyroid autoimmunity.
Clinical & developmental immunology 2005;12(1):47-58.
2005: Glenn Siegel; Yaron Tomer
Is there an association between acromegaly and thyroid carcinoma? A critical review of the literature.
Endocrine research 2005;31(1):51-8.
2004: Yoshiyuki Ban; Erlinda Concepcion; Ronald Villanueva; David A Greenberg; terry Davies; Yaron Tomer
Analysis of immune regulatory genes in familial and sporadic Graves' disease.
The Journal of clinical endocrinology and metabolism 2004;89(9):4562-8.
2004: Yael Oppenheim; Yoshiyuki Ban; Yaron Tomer
Interferon induced Autoimmune Thyroid Disease (AITD): a model for human autoimmunity.
Autoimmunity reviews 2004;3(5):388-93.
2004: Yaron Tomer; David Greenberg
The thyroglobulin gene as the first thyroid-specific susceptibility gene for autoimmune thyroid disease.
Trends in molecular medicine 2004;10(7):306-8.
2004: Lara Levin; Yoshiyuki Ban; Erlinda Concepcion; terry Davies; David A Greenberg; Yaron Tomer
Analysis of HLA genes in families with autoimmune diabetes and thyroiditis.
Human immunology 2004;65(6):640-7.
2004: Yoshiyuki Ban; terry Davies; David A Greenberg; Erlinda Concepcion; Roman Osman; T Oashi; Yaron Tomer
Arginine at position 74 of the HLA-DR beta1 chain is associated with Graves' disease.
Genes and immunity 2004;5(3):203-8.
2003: Yoshiyuki Ban; David A Greenberg; Erlinda Concepcion; Lucy Skrabanek; Ronald Villanueva; Yaron Tomer
Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15119-24.
2003: Yoshiyuki Ban; terry Davies; David A Greenberg; A Kissin; Brad Marder; Barbara Murphy; Erlinda Concepcion; Ronald Villanueva; Giuseppe Barbesino; V Ling; Yaron Tomer
Analysis of the CTLA-4, CD28, and inducible costimulator (ICOS) genes in autoimmune thyroid disease.
Genes and immunity 2003;4(8):586-93.
2003: Yaron Tomer; terry Davies
Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function.
Endocrine reviews 2003;24(5):694-717.
2003: Lara Levin; Yaron Tomer
The etiology of autoimmune diabetes and thyroiditis: evidence for common genetic susceptibility.
Autoimmunity reviews 2003;2(6):377-86.
2003: Yaron Tomer; Yoshiyuki Ban; Erlinda Concepcion; Giuseppe Barbesino; Ronald Villanueva; David A Greenberg; terry Davies
Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families.
American journal of human genetics 2003;73(4):736-47.
2003: Yoshiyuki Ban; Yaron Tomer
The contribution of immune regulatory and thyroid specific genes to the etiology of Graves' and Hashimoto's diseases.
Autoimmunity 2003;36(6-7):367-79.
2003: Ronald Villanueva; David A Greenberg; terry Davies; Yaron Tomer
Sibling recurrence risk in autoimmune thyroid disease.
Thyroid : official journal of the American Thyroid Association 2003;13(8):761-4.
2003: Yael Oppenheim; Grace Kim; Yoshiyuki Ban; Pamela Unger; Erlinda Concepcion; Takao Ando; Yaron Tomer
The effects of alpha interferon on the development of autoimmune thyroiditis in the NOD H2h4 mouse.
Clinical & developmental immunology 2003;10(2-4):161-5.
2003: Brad Marder; Bernd Schroppel; Marvin Lin; Thomas D Schiano; Rulan S Parekh; Yaron Tomer; Barbara Murphy
The impact of costimulatory molecule gene polymorphisms on clinical outcomes in liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(4):424-31.
2002: Yaron Tomer; Erlinda Concepcion; David A Greenberg
A C/T single-nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease.
Thyroid : official journal of the American Thyroid Association 2002;12(12):1129-35.
2002: Yoshiyuki Ban; David A Greenberg; Erlinda Concepcion; Yaron Tomer
A germline single nucleotide polymorphism at the intracellular domain of the human thyrotropin receptor does not have a major effect on the development of Graves' disease.
Thyroid : official journal of the American Thyroid Association 2002;12(12):1079-83.
2002: Sheera Siegel; Walter Futterweit; terry Davies; Erlinda Concepcion; David A Greenberg; Ronald Villanueva; Yaron Tomer
A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome.
Fertility and sterility 2002;78(6):1240-3.
2002: Yaron Tomer
Genetic dissection of familial autoimmune thyroid diseases using whole genome screening.
Autoimmunity reviews 2002;1(4):198-204.
2002: Yoshiyuki Ban; terry Davies; David A Greenberg; Erlinda Concepcion; Yaron Tomer
The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): results of studies in HLA-DR3 positive AITD families.
Clinical endocrinology 2002;57(1):81-8.
2002: Walter Futterweit; Luba Dronova; Yaron Tomer; Sheera Siegel
Pre-analytical errors: everything that happens to the specimen up to the point of testing.
Fertility and sterility 2002;77(4):855-6; author reply 856-7.
2002: Yang Xu; Peter N Graves; Yaron Tomer; terry Davies
CTLA-4 and autoimmune thyroid disease: lack of influence of the A49G signal peptide polymorphism on functional recombinant human CTLA-4.
Cellular immunology 2002;215(2):133-40.
2002: Ronald Villanueva; Yaron Tomer; David A Greenberg; C Mao; Erlinda Concepcion; S Tucci; G Estilo; terry Davies
Autoimmune thyroid disease susceptibility loci in a large Chinese family.
Clinical endocrinology 2002;56(1):45-51.
2002: Yaron Tomer; David A Greenberg; Erlinda Concepcion; Yoshiyuki Ban; terry Davies
Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases.
The Journal of clinical endocrinology and metabolism 2002;87(1):404-7.
2001: Yael Oppenheim; H C Yeh; Margaret Brandwein-Gensler; Yaron Tomer
Thyroid carcinoma in a patient with acromegaly.
Thyroid : official journal of the American Thyroid Association 2001;11(12):1197-8.
2001: E Slavcheva; Efsevia Albanis; Q Jiao; H Tran; Carol Bodian; R Knight; E Milford; Thomas D Schiano; Yaron Tomer; Barbara Murphy
Cytotoxic T-lymphocyte antigen 4 gene polymorphisms and susceptibility to acute allograft rejection.
Transplantation 2001;72(5):935-40.
2001: A E Schneider; Yaron Tomer
Images in thyroidology. Onycholysis associated with hypothyroidism.
Thyroid : official journal of the American Thyroid Association 2001;11(7):707.
2001: Yaron Tomer; David A Greenberg; Giuseppe Barbesino; Erlinda Concepcion; terry Davies
CTLA-4 and not CD28 is a susceptibility gene for thyroid autoantibody production.
The Journal of clinical endocrinology and metabolism 2001;86(4):1687-93.
2001: S Tucci; Walter Futterweit; Erlinda Concepcion; David A Greenberg; Ronald Villanueva; terry Davies; Yaron Tomer
Evidence for association of polycystic ovary syndrome in caucasian women with a marker at the insulin receptor gene locus.
The Journal of clinical endocrinology and metabolism 2001;86(1):446-9.
2000: Ronald Villanueva; Angela M Inzerillo; Yaron Tomer; Giuseppe Barbesino; M Meltzer; Erlinda Concepcion; David A Greenberg; Noel Maclaren; Z S Sun; D M Zhang; S Tucci; terry Davies
Limited genetic susceptibility to severe Graves' ophthalmopathy: no role for CTLA-4 but evidence for an environmental etiology.
Thyroid : official journal of the American Thyroid Association 2000;10(9):791-8.
2000: Yaron Tomer
Unilateral ophthalmopathy in a patient with Hashimoto's thyroiditis.
Thyroid : official journal of the American Thyroid Association 2000;10(1):99-100.
1999: Yaron Tomer; Giuseppe Barbesino; David A Greenberg; Erlinda Concepcion; terry Davies
Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: evidence for genetic heterogeneity and gene interactions.
The Journal of clinical endocrinology and metabolism 1999;84(12):4656-64.
1998: Yaron Tomer; Giuseppe Barbesino; David A Greenberg; Erlinda Concepcion; terry Davies
Linkage analysis of candidate genes in autoimmune thyroid disease. III. Detailed analysis of chromosome 14 localizes Graves' disease-1 (GD-1) close to multinodular goiter-1 (MNG-1). International Consortium for the Genetics of Autoimmune Thyroid Disease.
The Journal of clinical endocrinology and metabolism 1998;83(12):4321-7.
1998: Yaron Tomer; Giuseppe Barbesino; David A Greenberg; Erlinda Concepcion; terry Davies
A new Graves disease-susceptibility locus maps to chromosome 20q11.2. International Consortium for the Genetics of Autoimmune Thyroid Disease.
American journal of human genetics 1998;63(6):1749-56.
1998: Giuseppe Barbesino; Yaron Tomer; Erlinda Concepcion; terry Davies; David A Greenberg
Linkage analysis of candidate genes in autoimmune thyroid disease. II. Selected gender-related genes and the X-chromosome. International Consortium for the Genetics of Autoimmune Thyroid Disease.
The Journal of clinical endocrinology and metabolism 1998;83(9):3290-5.
1998: Giuseppe Barbesino; Yaron Tomer; Erlinda Concepcion; terry Davies; David A Greenberg
Linkage analysis of candidate genes in autoimmune thyroid disease: 1. Selected immunoregulatory genes. International Consortium for the Genetics of Autoimmune Thyroid Disease.
The Journal of clinical endocrinology and metabolism 1998;83(5):1580-4.
1997: Yaron Tomer; terry Davies
The genetic susceptibility to Graves' disease.
Baillière's clinical endocrinology and metabolism 1997;11(3):431-50.
1997: Yaron Tomer; Giuseppe Barbesino; M Keddache; David A Greenberg; terry Davies
Mapping of a major susceptibility locus for Graves' disease (GD-1) to chromosome 14q31.
The Journal of clinical endocrinology and metabolism 1997;82(5):1645-8.
1997: Yaron Tomer; Giuseppe Barbesino; D Greenberg; terry Davies
The immunogenetics of autoimmune diabetes and autoimmune thyroid disease.
Trends in endocrinology and metabolism: TEM 1997;8(2):63-70.
1995: H Vlase; M Nakashima; Peter N Graves; Yaron Tomer; J C Morris; terry Davies
Defining the major antibody epitopes on the human thyrotropin receptor in immunized mice: evidence for intramolecular epitope spreading.
Endocrinology 1995;136(10):4415-23.
1995: Yaron Tomer; terry Davies
Infections and autoimmune endocrine disease.
Baillière's clinical endocrinology and metabolism 1995;9(1):47-70.
1993: Yaron Tomer; terry Davies
Infection, thyroid disease, and autoimmunity.
Endocrine reviews 1993;14(1):107-20.
1993: Yaron Tomer; Peter N Graves; A Jin; A E Schwartz; E W Friedman; terry Davies
Liquid hybridization analysis of TSH receptor mRNA in normal and abnormal human thyroid tissues.
Thyroid : official journal of the American Thyroid Association 1993;3(3):219-24.
1992: Peter N Graves; Yaron Tomer; terry Davies
Cloning and sequencing of a 1.3 KB variant of human thyrotropin receptor mRNA lacking the transmembrane domain.
Biochemical and biophysical research communications 1992;187(2):1135-43.
1992: Yaron Tomer; G K Huber; terry Davies
Human chorionic gonadotropin (hCG) interacts directly with recombinant human TSH receptors.
The Journal of clinical endocrinology and metabolism 1992;74(6):1477-9.