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David Tomlinson

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
36
Fernyhough, Paul
23
Diemel, LT
20
Calcutt, Nigel
8
Delcroix, Jean-Dominique
7
Middlemas, Alicia
7
Gardiner, Natalie
7
Garrett, NE
7
Price, Sally
6
Hounsom, Luke
6
Malcangio, M
6
Dewhurst, M
5
Cruwys, Simon
5
Priestley, John
4
Vo, PA
4
Purves-Tyson, Tertia

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Publications

TOP 3
Tomlinson David R; Gardiner Natalie J
Diabetic neuropathies: components of etiology.
Tomlinson David R; Gardiner Natalie J
Glucose neurotoxicity.
Karamoysoyli Eugenia; Burnand Rebecca C; Tomlinson David R; Gardiner Natalie J
Neuritin mediates nerve growth factor-induced axonal regeneration and is deficient in experimental diabetic neuropathy.

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All Publications

2008: Tomlinson David R; Gardiner Natalie J
Diabetic neuropathies: components of etiology.
Journal of the peripheral nervous system : JPNS 2008;13(2):112-21.
2008: Tomlinson David R; Gardiner Natalie J
Glucose neurotoxicity.
Nature reviews. Neuroscience 2008;9(1):36-45.
2008: Karamoysoyli Eugenia; Burnand Rebecca C; Tomlinson David R; Gardiner Natalie J
Neuritin mediates nerve growth factor-induced axonal regeneration and is deficient in experimental diabetic neuropathy.
Diabetes 2008;57(1):181-9.
2007: Gardiner Natalie J; Moffatt Sarah; Fernyhough Paul; Humphries Martin J; Streuli Charles H; Tomlinson David R
Preconditioning injury-induced neurite outgrowth of adult rat sensory neurons on fibronectin is mediated by mobilisation of axonal alpha5 integrin.
Molecular and cellular neurosciences 2007;35(2):249-60.
2006: Price Sally A; Gardiner Natalie J; Duran-Jimenez Beatriz; Zeef Leo A H; Obrosova Irina G; Tomlinson David R
Thioredoxin interacting protein is increased in sensory neurons in experimental diabetes.
Brain research 2006;1116(1):206-14.
2006: Price Sally Amanda; Zeef Leo Arnoldus Hendrikus; Wardleworth Leanne; Hayes Andrew; Tomlinson David Richard
Identification of changes in gene expression in dorsal root ganglia in diabetic neuropathy: correlation with functional deficits.
Journal of neuropathology and experimental neurology 2006;65(7):722-32.
2006: Price Sally A; Dent Carolyn; Duran-Jimenez Beatriz; Liang Yuxin; Zhang Lei; Rebar Edward J; Case Casey C; Gregory Philip D; Martin Tyler J; Spratt S Kaye; Tomlinson David R
Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy.
Diabetes 2006;55(6):1847-54.
2006: Middlemas A B; Agthong S; Tomlinson D R
Phosphorylation of c-Jun N-terminal kinase (JNK) in sensory neurones of diabetic rats, with possible effects on nerve conduction and neuropathic pain: prevention with an aldose reductase inhibitor.
Diabetologia 2006;49(3):580-7.
2005: Gardiner Natalie J; Fernyhough Paul; Tomlinson David R; Mayer Ulrike; von der Mark Helga; Streuli Charles H
Alpha7 integrin mediates neurite outgrowth of distinct populations of adult sensory neurons.
Molecular and cellular neurosciences 2005;28(2):229-40.
2004: Burnand R C; Price S A; McElhaney M; Barker D; Tomlinson D R
Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes.
Brain research. Molecular brain research 2004;132(2):235-40.
2004: Chilton L; Middlemas A; Gardiner N; Tomlinson D R
The p75 neurotrophin receptor appears in plasma in diabetic rats-characterisation of a potential early test for neuropathy.
Diabetologia 2004;47(11):1924-30.
2004: Price Sally A; Agthong Sithiporn; Middlemas Alicia B; Tomlinson David R
Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase.
Diabetes 2004;53(7):1851-6.
2003: Price Sally A; Hounsom Luke; Purves-Tyson Tertia D; Fernyhough Paul; Tomlinson David R
Activation of JNK in sensory neurons protects against sensory neuron cell death in diabetes and on exposure to glucose/oxidative stress in vitro.
Annals of the New York Academy of Sciences 2003;1010():95-9.
2003: Delcroix Jean-Dominique; Patel Jyoti; Averill Sharon; Tomlinson David R; Priestley John V; Fernyhough Paul
Peripheral axon crush elevates transport of p75NTR in the central projection of sensory neurones of rats.
Neuroscience letters 2003;351(3):181-5.
2003: Sayers Nicola M; Beswick Lisa J; Middlemas Alicia; Calcutt Nigel A; Mizisin Andrew P; Tomlinson David R; Fernyhough Paul
Neurotrophin-3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of streptozocin-induced diabetic rats.
Diabetes 2003;52(9):2372-80.
2003: Huang Tze-Jen; Price Sally A; Chilton Lucy; Calcutt Nigel A; Tomlinson David R; Verkhratsky Alex; Fernyhough Paul
Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.
Diabetes 2003;52(8):2129-36.
2003: Middlemas A; Delcroix J-D; Sayers N M; Tomlinson D R; Fernyhough P
Enhanced activation of axonally transported stress-activated protein kinases in peripheral nerve in diabetic neuropathy is prevented by neurotrophin-3.
Brain : a journal of neurology 2003;126(Pt 7):1671-82.
2003: Calcutt Nigel A; Allendoerfer Karen L; Mizisin Andrew P; Middlemas Alicia; Freshwater Jason D; Burgers Monica; Ranciato Rigel; Delcroix Jean-Dominique; Taylor Frederick R; Shapiro Renee; Strauch Kathy; Dudek Henryk; Engber Thomas M; Galdes Alphonse; Rubin Lee L; Tomlinson David R
Therapeutic efficacy of sonic hedgehog protein in experimental diabetic neuropathy.
The Journal of clinical investigation 2003;111(4):507-14.
2002: Purves Tertia D; Tomlinson David R
Diminished transcription factor survival signals in dorsal root ganglia in rats with streptozotocin-induced diabetes.
Annals of the New York Academy of Sciences 2002;973():472-6.
2002: Agthong Sithiporn; Tomlinson David R
Inhibition of p38 MAP kinase corrects biochemical and neurological deficits in experimental diabetic neuropathy.
Annals of the New York Academy of Sciences 2002;973():359-62.
2002: Purves Tertia D; Tomlinson David R
Are mitogen-activated protein kinases glucose transducers for diabetic neuropathies?
International review of neurobiology 2002;50():83-114.
2001: Purves T; Middlemas A; Agthong S; Jude E B; Boulton A J; Fernyhough P; Tomlinson D R
A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2508-14.
2001: Vo P A; Tomlinson D R
Effects of nerve growth factor on expression of GAP-43 in right atria after sympathectomy in diabetic rats.
Diabetes, obesity & metabolism 2001;3(5):350-9.
2001: Averill S; Delcroix J D; Michael G J; Tomlinson D R; Fernyhough P; Priestley J V
Nerve growth factor modulates the activation status and fast axonal transport of ERK 1/2 in adult nociceptive neurones.
Molecular and cellular neurosciences 2001;18(2):183-96.
2001: Eckersley L; Ansselin A D; Tomlinson D R
Effects of experimental diabetes on axonal and Schwann cell changes in sciatic nerve isografts.
Brain research. Molecular brain research 2001;92(1-2):128-37.
2001: Hounsom L; Corder R; Patel J; Tomlinson D R
Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy.
Diabetologia 2001;44(4):424-8.
2000: Samina Riaz S; Tomlinson D R
Pharmacological modulation of nerve growth factor synthesis: a mechanistic comparison of vitamin D receptor and beta(2)-adrenoceptor agonists.
Brain research. Molecular brain research 2000;85(1-2):179-88.
2000: Kendall S; Yeo M; Henttu P; Tomlinson D R
Alternative splicing of the neurotrophin-3 gene gives rise to different transcripts in a number of human and rat tissues.
Journal of neurochemistry 2000;75(1):41-7.
2000: Schmidt R E; Dorsey D A; Roth K A; Parvin C A; Hounsom L; Tomlinson D R
Effect of streptozotocin-induced diabetes on NGF, P75(NTR) and TrkA content of prevertebral and paravertebral rat sympathetic ganglia.
Brain research 2000;867(1-2):149-56.
1999: Riaz S; Malcangio M; Miller M; Tomlinson D R
A vitamin D(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats.
Diabetologia 1999;42(11):1308-13.
1999: Tomlinson D R
Mitogen-activated protein kinases as glucose transducers for diabetic complications.
Diabetologia 1999;42(11):1271-81.
1999: Patel J; Tomlinson D R
Nerve conduction impairment in experimental diabetes-proximodistal gradient of severity.
Muscle & nerve 1999;22(10):1403-11.
1999: Delcroix J D; Averill S; Fernandes K; Tomlinson D R; Priestley J V; Fernyhough P
Axonal transport of activating transcription factor-2 is modulated by nerve growth factor in nociceptive neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(18):RC24.
1999: Cai F; Campana W M; Tomlinson D R; Fernyhough P
Transforming growth factor-beta1 and glial growth factor 2 reduce neurotrophin-3 mRNA expression in cultured Schwann cells via a cAMP-dependent pathway.
Brain research. Molecular brain research 1999;71(2):256-64.
1999: Vo P A; Tomlinson D R
The regeneration of peripheral noradrenergic nerves after chemical sympathectomy in diabetic rats: effects of nerve growth factor.
Experimental neurology 1999;157(1):127-34.
1999: Tandrup T; Vestergaard S; Tomlinson D R; Diemel L T; Jakobsen J
The structural effect of systemic NGF treatment on permanently axotomised dorsal root ganglion cells in adult rats.
Journal of anatomy 1999;194 ( Pt 3)():373-9.
1999: Fernyhough P; Gallagher A; Averill S A; Priestley J V; Hounsom L; Patel J; Tomlinson D R
Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy.
Diabetes 1999;48(4):881-9.
1999: Cai F; Tomlinson D R; Fernyhough P
Elevated expression of neurotrophin-3 mRNA in sensory nerve of streptozotocin-diabetic rats.
Neuroscience letters 1999;263(2-3):81-4.
1999: Diemel L T; Cai F; Anand P; Warner G; Kopelman P G; Fernyhough P; Tomlinson D R
Increased nerve growth factor mRNA in lateral calf skin biopsies from diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 1999;16(2):113-8.
1999: Mizisin A P; Calcutt N A; Tomlinson D R; Gallagher A; Fernyhough P
Neurotrophin-3 reverses nerve conduction velocity deficits in streptozotocin-diabetic rats.
Journal of the peripheral nervous system : JPNS 1999;4(3-4):211-21.
1999: Mohiuddin L; Delcroix J D; Fernyhough P; Tomlinson D R
Focally administered nerve growth factor suppresses molecular regenerative responses of axotomized peripheral afferents in rats.
Neuroscience 1999;91(1):265-71.
1998: Malcangio M; Fernandes K; Tomlinson D R
NMDA receptor activation modulates evoked release of substance P from rat spinal cord.
British journal of pharmacology 1998;125(8):1625-6.
1998: Tomlinson D R
Future prevention and treatment of diabetic neuropathy.
Diabetes & metabolism 1998;24 Suppl 3():79-83.
1998: Delcroix J D; Michael G J; Priestley J V; Tomlinson D R; Fernyhough P
Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats.
Diabetes 1998;47(11):1779-85.
1998: Cai F; Tomlinson D R; Fernyhough P
Effect of sciatic nerve crush on local and target tissue production of neurotrophin-3 transcripts in rats.
Neuroscience letters 1998;252(1):45-8.
1998: Fernyhough P; Brewster W J; Fernandes K; Diemel L T; Tomlinson D R
Stimulation of nerve growth-factor and substance P expression in the iris-trigeminal axis of diabetic rats--involvement of oxidative stress and effects of aldose reductase inhibition.
Brain research 1998;802(1-2):247-53.
1998: Bennett G S; Garrett N E; Diemel L T; Brain S D; Tomlinson D R
Neurogenic cutaneous vasodilatation and plasma extravasation in diabetic rats: effect of insulin and nerve growth factor.
British journal of pharmacology 1998;124(7):1573-9.
1998: Hounsom L; Horrobin D F; Tritschler H; Corder R; Tomlinson D R
A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy.
Diabetologia 1998;41(7):839-43.
1998: Tomlinson D R; Dewhurst M; Stevens E J; Omawari N; Carrington A L; Vo P A
Reduced nerve blood flow in diabetic rats: relationship to nitric oxide production and inhibition of aldose reductase.
Diabetic medicine : a journal of the British Diabetic Association 1998;15(7):579-85.
1998: Malcangio M; Tomlinson D R
A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats.
Pain 1998;76(1-2):151-7.
1998: Fernyhough P; Diemel L T; Tomlinson D R
Target tissue production and axonal transport of neurotrophin-3 are reduced in streptozotocin-diabetic rats.
Diabetologia 1998;41(3):300-6.
1997: Mohiuddin L; Tomlinson D R
Impaired molecular regenerative responses in sensory neurones of diabetic rats: gene expression changes in dorsal root ganglia after sciatic nerve crush.
Diabetes 1997;46(12):2057-62.
1997: Delcroix J D; Tomlinson D R; Fernyhough P
Diabetes and axotomy-induced deficits in retrograde axonal transport of nerve growth factor correlate with decreased levels of p75LNTR protein in lumbar dorsal root ganglia.
Brain research. Molecular brain research 1997;51(1-2):82-90.
1997: Malcangio M; Garrett N E; Cruwys S; Tomlinson D R
Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8459-67.
1997: Tomlinson D R; Fernyhough P; Diemel L T
Role of neurotrophins in diabetic neuropathy and treatment with nerve growth factors.
Diabetes 1997;46 Suppl 2():S43-9.
1997: Garrett N E; Cruwys S C; Kidd B L; Tomlinson D R
Effect of capsaicin on substance P and nerve growth factor in adjuvant arthritic rats.
Neuroscience letters 1997;230(1):5-8.
1997: Vo P A; Tomlinson D R
Effects of adrenergic stimulation on sciatic nerve blood flow in diabetic and control rats.
European journal of pharmacology 1997;329(2-3):147-52.
1997: Malcangio M; Garrett N E; Tomlinson D R
Nerve growth factor treatment increases stimulus-evoked release of sensory neuropeptides in the rat spinal cord.
The European journal of neuroscience 1997;9(5):1101-4.
1997: Dewhurst M; Stevens E J; Tomlinson D R
Effects of aminoguanidine and N(G)-nitro-L-arginine methyl ester on vascular responses of aortae and lungs from streptozotocin-diabetic rats.
Prostaglandins, leukotrienes, and essential fatty acids 1997;56(4):317-24.
1997: Garrett N E; Malcangio M; Dewhurst M; Tomlinson D R
alpha-Lipoic acid corrects neuropeptide deficits in diabetic rats via induction of trophic support.
Neuroscience letters 1997;222(3):191-4.
1997: Fang C; Jiang Z; Tomlinson D R
Expression of constitutive cyclo-oxygenase (COX-1) in rats with streptozotocin-induced diabetes; effects of treatment with evening primrose oil or an aldose reductase inhibitor on COX-1 mRNA levels.
Prostaglandins, leukotrienes, and essential fatty acids 1997;56(2):157-63.
1997: Dewhurst M; Omawari N; Tomlinson D R
Aminoguanidine--effects on endoneurial vasoactive nitric oxide and on motor nerve conduction velocity in control and streptozotocin-diabetic rats.
British journal of pharmacology 1997;120(4):593-8.
1997: Hounsom L; Tomlinson D R
Does neuropathy develop in animal models?
Clinical neuroscience (New York, N.Y.) 1997;4(6):380-9.
1996: Garrett N E; Kidd B L; Cruwys S C; Tomlinson D R
Effect of streptozotocin-diabetes on knee joint inflammation-induced changes in substance P and nerve growth factor in the rat.
Brain research. Molecular brain research 1996;42(2):272-8.
1996: Mohiuddin L; Fernyhough P; Tomlinson D R
Acidic fibroblast growth factor enhances neurite outgrowth and stimulates expression of GAP-43 and T alpha 1 alpha-tubulin in cultured neurones from adult rat dorsal root ganglia.
Neuroscience letters 1996;215(2):111-4.
1996: Biessels G J; Stevens E J; Mahmood S J; Gispen W H; Tomlinson D R
Insulin partially reverses deficits in peripheral nerve blood flow and conduction in experimental diabetes.
Journal of the neurological sciences 1996;140(1-2):12-20.
1996: Tomlinson D R; Fernyhough P; Diemel L T; Maeda K
Deficient neurotrophic support in the aetiology of diabetic neuropathy.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(7):679-81.
1996: Belai A; Calcutt N A; Carrington A L; Diemel L T; Tomlinson D R; Burnstock G
Enteric neuropeptides in streptozotocin-diabetic rats; effects of insulin and aldose reductase inhibition.
Journal of the autonomic nervous system 1996;58(3):163-9.
1996: Omawari N; Dewhurst M; Vo P; Mahmood S; Stevens E; Tomlinson D R
Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L-NAME, L-arginine, sodium nitroprusside and evening primrose oil.
British journal of pharmacology 1996;118(1):186-90.
1996: Tomlinson D R; Fernyhough P; Diemel L T
Neurotrophins and peripheral neuropathy.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1338):455-62.
1995: Milner P; Crowe R; Fernyhough P; Diemel L T; Tomlinson D R; Burnstock G
Nerve growth factor treatment of adult rats selectively enhances innervation of urinogenital tract rather than vascular smooth muscle.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1995;13(5):393-401.
1995: Stevens E J; Tomlinson D R
Effects of endothelin receptor antagonism with bosentan on peripheral nerve function in experimental diabetes.
British journal of pharmacology 1995;115(2):373-9.
1995: Fernyhough P; Diemel L T; Hardy J; Brewster W J; Mohiuddin L; Tomlinson D R
Human recombinant nerve growth factor replaces deficient neurotrophic support in the diabetic rat.
The European journal of neuroscience 1995;7(5):1107-10.
1995: Fernyhough P; Diemel L T; Brewster W J; Tomlinson D R
Altered neurotrophin mRNA levels in peripheral nerve and skeletal muscle of experimentally diabetic rats.
Journal of neurochemistry 1995;64(3):1231-7.
1995: Brewster W J; Fernyhough P; Diemel L T; Mohiuddin L; Tomlinson D R
Changes in nerve growth factor and preprotachykinin messenger RNA levels in the iris and trigeminal ganglion in diabetic rats; effects of treatment with insulin or nerve growth factor.
Brain research. Molecular brain research 1995;29(1):131-9.
1995: Garrett N E; Kidd B L; Cruwys S C; Tomlinson D R
Streptozotocin-induced diabetes decreases substance P levels in experimental arthritis in the rat knee.
Neuroscience letters 1995;187(3):201-4.
1995: Garrett N E; Kidd B L; Cruwys S C; Tomlinson D R
Changes in preprotachykinin mRNA expression and substance P levels in dorsal root ganglia of monoarthritic rats: comparison with changes in synovial substance P levels.
Brain research 1995;675(1-2):203-7.
1995: Mohiuddin L; Fernandez K; Tomlinson D R; Fernyhough P
Nerve growth factor and neurotrophin-3 enhance neurite outgrowth and up-regulate the levels of messenger RNA for growth-associated protein GAP-43 and T alpha 1 alpha-tubulin in cultured adult rat sensory neurones.
Neuroscience letters 1995;185(1):20-3.
1995: Karasu C; Dewhurst M; Stevens E J; Tomlinson D R
Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids.
Diabetologia 1995;38(2):129-34.
1995: Mohiuddin L; Fernyhough P; Tomlinson D R
Reduced levels of mRNA encoding endoskeletal and growth-associated proteins in sensory ganglia in experimental diabetes.
Diabetes 1995;44(1):25-30.
1994: Fernyhough P; Diemel L T; Brewster W J; Tomlinson D R
Deficits in sciatic nerve neuropeptide content coincide with a reduction in target tissue nerve growth factor messenger RNA in streptozotocin-diabetic rats: effects of insulin treatment.
Neuroscience 1994;62(2):337-44.
1994: Brewster W J; Fernyhough P; Diemel L T; Mohiuddin L; Tomlinson D R
Diabetic neuropathy, nerve growth factor and other neurotrophic factors.
Trends in neurosciences 1994;17(8):321-5.
1994: Tomlinson D R; Stevens E J; Diemel L T
Aldose reductase inhibitors and their potential for the treatment of diabetic complications.
Trends in pharmacological sciences 1994;15(8):293-7.
1994: Carrington A L; Ettlinger C B; Tomlinson D R
Increased resistance to hypoxic conduction block in sciatic nerves of diabetic rats: effects of extracellular glucose concentration and of aldose reductase inhibition.
Journal of diabetes and its complications 1994;8(1):33-9.
1994: Stevens E J; Carrington A L; Tomlinson D R
Nerve ischaemia in diabetic rats: time-course of development, effect of insulin treatment plus comparison of streptozotocin and BB models.
Diabetologia 1994;37(1):43-8.
1994: Diemel L T; Brewster W J; Fernyhough P; Tomlinson D R
Expression of neuropeptides in experimental diabetes; effects of treatment with nerve growth factor or brain-derived neurotrophic factor.
Brain research. Molecular brain research 1994;21(1-2):171-5.
1994: Brewster W J; Diemel L T; Leach R M; Tomlinson D R
Reduced sciatic nerve substance P and calcitonin gene-related peptide in rats with short-term diabetes or central hypoxaemia co-exist with normal messenger RNA levels in the lumbar dorsal root ganglia.
Neuroscience 1994;58(2):323-30.
1993: Stevens E J; Carrington A L; Tomlinson D R
Prostacyclin release in experimental diabetes: effects of evening primrose oil.
Prostaglandins, leukotrienes, and essential fatty acids 1993;49(3):699-706.
1993: Stevens E J; Willars G B; Lidbury P; House F; Tomlinson D R
Vasoreactivity and prostacyclin release in streptozotocin-diabetic rats: effects of insulin or aldose reductase inhibition.
British journal of pharmacology 1993;109(4):980-6.
1993: Carrington A L; Calcutt N A; Ettlinger C B; Gustafsson T; Tomlinson D R
Effects of treatment with myo-inositol or its 1,2,6-trisphosphate (PP56) on nerve conduction in streptozotocin-diabetes.
European journal of pharmacology 1993;237(2-3):257-63.
1993: Stevens E J; Lockett M J; Carrington A L; Tomlinson D R
Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus.
Diabetologia 1993;36(5):397-401.
1993: Tomlinson D R
Aldose reductase inhibitors and the complications of diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 1993;10(3):214-30.
1993: Fernyhough P; Willars G B; Lindsay R M; Tomlinson D R
Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones.
Brain research 1993;607(1-2):117-24.
1993: Singh J K; Diemel L T; Willars G B; Tomlinson D R
The extraction and assay of substance P in the rat sciatic nerve.
Journal of neuroscience methods 1993;47(1-2):133-7.
1993: Tomlinson D R; Carrington A L; Diemel L T; Ettlinger C B; Smith W J; Fernyhough P
Limitations of the polyol hypothesis in the pathobiology of experimental diabetic neuropathy.
Diabetic medicine : a journal of the British Diabetic Association 1993;10 Suppl 2():27S-30S.
1992: Calcutt N A; Carrington A L; Ettlinger C B; Tomlinson D R
The effect of mixed bovine brain gangliosides on hypoxic conduction block in control and streptozotocin-diabetic rats.
Journal of the neurological sciences 1992;109(1):96-101.
1992: Diemel L T; Stevens E J; Willars G B; Tomlinson D R
Depletion of substance P and calcitonin gene-related peptide in sciatic nerve of rats with experimental diabetes; effects of insulin and aldose reductase inhibition.
Neuroscience letters 1992;137(2):253-6.
1992: Lockett M J; Tomlinson D R
The effects of dietary treatment with essential fatty acids on sciatic nerve conduction and activity of the Na+/K+ pump in streptozotocin-diabetic rats.
British journal of pharmacology 1992;105(2):355-60.
1992: Tomlinson D R; Willars G B; Carrington A L
Aldose reductase inhibitors and diabetic complications.
Pharmacology & therapeutics 1992;54(2):151-94.
1991: Willars G B; Calcutt N A; Tomlinson D R
Nerve conduction velocity and axonal transport of 6-phosphofructokinase activity in galactose-fed rats.
Journal of the neurological sciences 1991;104(1):46-51.
1991: Carrington A L; Ettlinger C B; Calcutt N A; Tomlinson D R
Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats.
Diabetologia 1991;34(6):397-401.
1991: Calcutt N A; Ettlinger C B; Carrington A L; Diemel L; Tomlinson D R
Resistance to hypoxic conduction block in sciatic nerves of rats with streptozotocin-induced diabetes mellitus.
Journal of the neurological sciences 1991;103(1):116-23.
1991: Smith W J; Diemel L T; Leach R M; Tomlinson D R
Central hypoxaemia in rats provokes neurological defects similar to those seen in experimental diabetes mellitus: evidence for a partial role of endoneurial hypoxia in diabetic neuropathy.
Neuroscience 1991;45(2):255-9.
1990: Calcutt N A; Tomlinson D R; Biswas S
Coexistence of nerve conduction deficit with increased Na(+)-K(+)-ATPase activity in galactose-fed mice. Implications for polyol pathway and diabetic neuropathy.
Diabetes 1990;39(6):663-6.
1990: Calcutt N A; Tomlinson D R; Willars G B; Keen P
Axonal transport of substance P-like immunoreactivity in ganglioside-treated diabetic rats.
Journal of the neurological sciences 1990;96(2-3):283-91.
1990: Tomlinson D R; Filliatreau G; Figliomeni B; Hassig R; Di Giamberardino L; Willars G B
Proteins of slow axonal transport in sciatic motoneurones of rats with streptozotocin-induced diabetes or galactosaemia.
Diabetes research and clinical practice 1990;9(1):15-21.
1989: Tomlinson D R; Robinson J P; Compton A M; Keen P
Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats.
Diabetologia 1989;32(9):655-9.
1989: Willars G B; Calcutt N A; Compton A M; Tomlinson D R; Keen P
Substance P levels in peripheral nerve, skin, atrial myocardium and gastrointestinal tract of rats with long-term diabetes mellitus. Effects of aldose reductase inhibition.
Journal of the neurological sciences 1989;91(1-2):153-64.
1989: Tomlinson D R; Willars G B; Calcutt N A; Compton A M; Macdonald I A; Clarke H E; Keen P
Effects of sorbinil treatment in rats with chronic streptozotocin-diabetes; changes in lens and in substance P and catecholamines in the iris.
Current eye research 1989;8(4):357-63.
1988: Calcutt N A; Willars G B; Tomlinson D R
Axonal transport of choline acetyltransferase and 6-phosphofructokinase activities in genetically diabetic mice.
Muscle & nerve 1988;11(12):1206-10.
1988: Fone K C; Dix P; Tomlinson D R; Bennett G W; Marsden C A
Spinal effects of chronic intrathecal administration of the thyrotrophin-releasing hormone analogue (CG 3509) in rats.
Brain research 1988;455(1):157-61.
1988: Lambourne J E; Brown A M; Calcutt N; Tomlinson D R; Willars G B
Adenosine triphosphatase in nerves and ganglia of rats with streptozotocin-induced diabetes or galactosaemia; effects of aldose reductase inhibition.
Diabetologia 1988;31(6):379-84.
1988: Calcutt N A; Willars G B; Tomlinson D R
Statil-sensitive polyol formation in nerve of galactose-fed mice.
Metabolism: clinical and experimental 1988;37(5):450-3.
1988: Willars G B; Townsend J; Tomlinson D R; Compton A M; Churchill R D
Studies on peripheral nerve and lens in long-term experimental diabetes: effects of the aldose reductase inhibitor statil.
Metabolism: clinical and experimental 1988;37(5):442-9.
1988: Calcutt N A; Tomlinson D R; Willars G B
Ganglioside treatment of streptozotocin-diabetic rats prevents defective axonal transport of 6-phosphofructokinase activity.
Journal of neurochemistry 1988;50(5):1478-83.
1988: Tomlinson D R; Robinson J P; Willars G B; Keen P
Deficient axonal transport of substance P in streptozocin-induced diabetic rats. Effects of sorbinil and insulin.
Diabetes 1988;37(4):488-93.
1988: Calcutt N A; Tomlinson D R; Willars G B
Ganglioside treatment of diabetic rats; effects on nerve adenosine triphosphatase activity and motor nerve conduction velocity.
Life sciences 1988;42(16):1515-20.
1987: Willars G B; Lambourne J E; Tomlinson D R
Does galactose feeding provide a valid model of consequences of exaggerated polyol-pathway flux in peripheral nerve in experimental diabetes?
Diabetes 1987;36(12):1425-31.
1987: Robinson J P; Willars G B; Tomlinson D R; Keen P
Axonal transport and tissue contents of substance P in rats with long-term streptozotocin-diabetes. Effects of the aldose reductase inhibitor 'statil'.
Brain research 1987;426(2):339-48.
1987: Robinson J P; Tomlinson D R
Fast anterograde axonal transport of choline-containing lipids in rats with experimental diabetes.
Journal of the neurological sciences 1987;81(1):93-100.
1987: Lambourne J E; Tomlinson D R; Brown A M; Willars G B
Opposite effects of diabetes and galactosaemia on adenosine triphosphatase activity in rat nervous tissue.
Diabetologia 1987;30(5):360-2.
1987: Willars G B; Calcutt N A; Tomlinson D R
Reduced anterograde and retrograde accumulation of axonally transported phosphofructokinase in streptozotocin-diabetic rats: effects of insulin and the aldose reductase inhibitor 'Statil'.
Diabetologia 1987;30(4):239-43.

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