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Hiroshi Tomoda

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Masaki Ohtawa; Lawrence L Rudel; Hiroshi Tomoda; Hiroyuki Yamazaki; Satoshi Omura; Daisuke Matsuda; Taichi Ohshiro; Tohru Nagamitsu
Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 2.
Mio Kawaguchi; Keisuke Kobayashi; Rokuro Masuma; Natsuki Miyachi; Kenichi Nonaka; Satoshi Ohte; Noriko Sato; Ryuji Uchida; Tadashi Yasuhara; Takashi Fukuda; Hiroshi Tomoda
New dinapinone derivatives, potent inhibitors of triacylglycerol synthesis in mammalian cells, produced by Talaromyces pinophilus FKI-3864.
Masaki Ohtawa; Satoshi Ohte; Satoshi Omura; Lawrence L Rudel; Hiroshi Tomoda; Hiroyuki Yamazaki; Daisuke Matsuda; Taichi Ohshiro; Tohru Nagamitsu
Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 1.

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2013: Masaki Ohtawa; Lawrence L Rudel; Hiroshi Tomoda; Hiroyuki Yamazaki; Satoshi Omura; Daisuke Matsuda; Taichi Ohshiro; Tohru Nagamitsu
Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 2.
Bioorganic & medicinal chemistry letters 2013;23(9):2659-62.
2013: Mio Kawaguchi; Keisuke Kobayashi; Rokuro Masuma; Natsuki Miyachi; Kenichi Nonaka; Satoshi Ohte; Noriko Sato; Ryuji Uchida; Tadashi Yasuhara; Takashi Fukuda; Hiroshi Tomoda
New dinapinone derivatives, potent inhibitors of triacylglycerol synthesis in mammalian cells, produced by Talaromyces pinophilus FKI-3864.
The Journal of antibiotics 2013;66(3):179-89.
2013: Masaki Ohtawa; Satoshi Ohte; Satoshi Omura; Lawrence L Rudel; Hiroshi Tomoda; Hiroyuki Yamazaki; Daisuke Matsuda; Taichi Ohshiro; Tohru Nagamitsu
Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 1.
Bioorganic & medicinal chemistry letters 2013;23(5):1285-7.
2013: Nobuhiro Koyama; Yoko Takahashi; Yuriko Tokura; Hiroshi Tomoda
Discovery of nosokophic acid, a predicted intermediate of moenomycins, from nosokomycin-producing Streptomyces sp. K04-0144.
Bioorganic & medicinal chemistry letters 2013;23(3):860-3.
2013: Keisuke Kobayashi; Daisuke Matsuda; Taichi Ohshiro; Shuyi Si; Bin Hong; Wei Jiang; Hiroshi Tomoda
The mechanism of action of bufalin in inhibition of lipid droplet accumulation in mouse macrophages.
Biological & pharmaceutical bulletin 2013;36(3):364-9.
2013: Junji Inokoshi; Rokuro Masuma; Yuichiro Nakamura; Ken-ichi Nonaka; Zhang Hongbin; Ryuji Uchida; Hiroshi Tomoda
Spirohexalines, new inhibitors of bacterial undecaprenyl pyrophosphate synthase, produced by Penicillium brasilianum FKI-3368.
The Journal of antibiotics 2013;66(1):37-41.
2013: Mio Kawaguchi; Rokuro Masuma; Kenichi Nonaka; Takashi Fukuda; Ryuji Uchida; Hiroshi Tomoda
A new ascochlorin derivative from Cylindrocarpon sp. FKI-4602.
The Journal of antibiotics 2013;66(1):23-9.
2013: Mio Kawaguchi; Rokuro Masuma; Kenichi Nonaka; Hiroshi Tomoda
New method for isolating antibiotic-producing fungi.
The Journal of antibiotics 2013;66(1):17-21.
2012: Takashi Fukuda; Kenichiro Nagai; Hiroshi Tomoda
(±)-Tylopilusins, diphenolic metabolites from the fruiting bodies of Tylopilus eximius.
Journal of natural products 2012;75(12):2228-31.
2012: Kenichiro Nagai; Noriko Sato; Nobuhiro Koyama; Chisato Yanagisawa; Hiroshi Tomoda
Synthesis and antimycobacterial activity of calpinactam derivatives.
Bioorganic & medicinal chemistry letters 2012;22(24):7739-41.
2012: Takashi Fukuda; Hiroyo Inoue; Takenobu Katagiri; Rokuro Masuma; Daisuke Matsuda; Kenichi Nonaka; Satoshi Ohte; Ryuji Uchida; Hiroyuki Yamazaki; Hiroshi Tomoda
Trichocyalides A and B, new inhibitors of alkaline phosphatase activity in bone morphogenetic protein-stimulated myoblasts, produced by Trichoderma sp. FKI-5513.
The Journal of antibiotics 2012;65(11):565-9.
2012: Ryuji Uchida; Hiroyuki Yamazaki; Mio Kawaguchi; Kyosuke Kawamoto; Satoshi Ohte; Hiroshi Tomoda
Structures and absolute stereochemistry of dinapinones A1 and A2, inhibitors of triacylglycerol synthesis, produced by penicillium pinophilum FKI-3864.
The Journal of antibiotics 2012;65(8):419-25.
2012: Junji Inokoshi; Maki Matsuhama; Midori Miyake; Haruo Ikeda; Hiroshi Tomoda
Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171.
Applied microbiology and biotechnology 2012;95(2):451-60.
2012: Taichi Ohshiro; Ryuji Uchida; Takeuchi Kazuhiro; Rokuro Masuma; Daisuke Matsuda; Kenichi Nonaka; Hiroshi Tomoda
New verticilides, inhibitors of acyl-CoA:cholesterol acyltransferase, produced by Verticillium sp. FKI-2679.
The Journal of antibiotics 2012;65(5):255-62.
2012: Nobuhiro Koyama; Junji Inokoshi; Hiroshi Tomoda
Anti-infectious agents against MRSA.
Molecules (Basel, Switzerland) 2012;18(1):204-24.
2012: Nobuhiro Koyama; Daniela Münch; Hans-Georg Sahl; Tanja Schneider; Yoshio Shibagaki; Yuriko Tokura; Haruo Ikeda; Hiroshi Tomoda
The nonantibiotic small molecule cyslabdan enhances the potency of β-lactams against MRSA by inhibiting pentaglycine interpeptide bridge synthesis.
PloS one 2012;7(11):e48981.
2012: Narihiro Ugaki; Hiroyuki Yamazaki; Ryuji Uchida; Hiroshi Tomoda
New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942: II. structure elucidation.
The Journal of antibiotics 2012;65(1):21-4.
2012: Narihiro Ugaki; Hiroyuki Yamazaki; Rokuro Masuma; Daisuke Matsuda; Kenichi Nonaka; Satoshi Omura; Hiroshi Tomoda
New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942: I. Taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 2012;65(1):15-9.
2011: Taichi Ohshiro; Hiroshi Tomoda
Isoform-specific inhibitors of ACATs: recent advances and promising developments.
Future medicinal chemistry 2011;3(16):2039-61.
2011: Kyosuke Kawamoto; Rokuro Masuma; Satoshi Ohte; Ryuji Uchida; Hiroyuki Yamazaki; Hiroshi Tomoda
Production of monapinones by fermentation of the dinapinone-producing fungus Penicillium pinophilum FKI-3864 in a seawater-containing medium.
The Journal of antibiotics 2011;64(7):503-8.
2011: Satoshi Ohte; Satoshi Omura; Rokuro Masuma; Daisuke Matsuda; Kenichi Nonaka; Ryuji Uchida; Hiroshi Tomoda
Dinapinones, novel inhibitors of triacylglycerol synthesis in mammalian cells, produced by Penicillium pinophilum FKI-3864.
The Journal of antibiotics 2011;64(7):489-94.
2011: Taichi Ohshiro; Daisuke Matsuda; Kent Sakai; Chiara Degirolamo; Hiroaki Yagyu; Lawrence L Rudel; Satoshi Omura; Shun Ishibashi; Hiroshi Tomoda
Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(5):1108-15.
2011: Naoshi Yamamoto; Hideaki Fujii; Satomi Imaide; Shigeto Hirayama; Toru Nemoto; Junji Inokoshi; Hiroshi Tomoda; Hiroshi Nagase
Synthesis of (-)-homogalanthamine from naltrexone.
The Journal of organic chemistry 2011;76(7):2257-60.
2011: Tomoko Miyagawa; Keisuke Nagai; Asami Yamada; Yoshinori Sugihara; Takashi Fukuda; Takashi Fukuda; Ryuji Uchida; Hiroshi Tomoda; Satoshi Omura; Tohru Nagamitsu
Total synthesis of citridone A.
Organic letters 2011;13(5):1158-61.
2011: Daisuke Yamamuro; Ryuji Uchida; Rokuro Masuma; Yoko Takahashi; Hiroshi Tomoda
Screening for microbial metabolites affecting phenotype of Caenorhabditis elegans.
Biological & pharmaceutical bulletin 2011;34(10):1619-23.
2010: Masumi Katane; Yasuaki Saitoh; Toshihiko Hanai; Masae Sekine; Takemitsu Furuchi; Nobuhiro Koyama; Izumi Nakagome; Hiroshi Tomoda; Shuichi Hirono; Hiroshi Homma
Thiolactomycin inhibits D-aspartate oxidase: a novel approach to probing the active site environment.
Biochimie 2010;92(10):1371-8.
2010: Daisuke Matsuda; Hiroshi Tomoda
Triazolo compounds useful as diacylglycerol acyltransferase1 inhibitor - WO2009126624.
Expert opinion on therapeutic patents 2010;20(8):1097-102.
2010: Hiroyuki Yamazaki; Satoshi Omura; Hiroshi Tomoda
6'-Hydroxy-3'-methoxy-mitorubrin, a new potentiator of antifungal miconazole activity, produced by Penicillium radicum FKI-3765-2.
Chemical & pharmaceutical bulletin 2010;58(6):829-32.
2010: Hiroyuki Yamazaki; Satoshi Omura; Hiroshi Tomoda
Xanthoradone C, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2.
The Journal of antibiotics 2010;63(6):329-30.
2010: Hiroyuki Yamazaki; Narihiro Ugaki; Daisuke Matsuda; Hiroshi Tomoda
Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1.
The Journal of antibiotics 2010;63(6):315-8.
2010: Hiroyuki Yamazaki; Nobuhiro Koyama; Satoshi Omura; Hiroshi Tomoda
New rugulosins, anti-MRSA antibiotics, produced by Penicillium radicum FKI-3765-2.
Organic letters 2010;12(7):1572-5.
2010: Ryuji Uchida; Masato Iwatsuki; Yong-Pil Kim; Satoshi Omura; Hiroshi Tomoda
Nosokomycins, new antibiotics discovered in an in vivo-mimic infection model using silkworm larvae. II: Structure elucidation.
The Journal of antibiotics 2010;63(4):157-63.
2010: Nobuhiro Koyama; Shigenobu Kojima; Kenichi Nonaka; Rokuro Masuma; Makoto Matsumoto; Satoshi Omura; Hiroshi Tomoda
Calpinactam, a new anti-mycobacterial agent, produced by Mortierella alpina FKI-4905.
The Journal of antibiotics 2010;63(4):183-6.
2010: Ryuji Uchida; Masato Iwatsuki; Yong-Pil Kim; Satoshi Ohte; Satoshi Omura; Hiroshi Tomoda
Nosokomycins, new antibiotics discovered in an in vivo-mimic infection model using silkworm larvae. I: Fermentation, isolation and biological properties.
The Journal of antibiotics 2010;63(4):151-5.
2010: Nobuhiro Koyama; Shigenobu Kojima; Takeo Fukuda; Tohru Nagamitsu; Tadashi Yasuhara; Satoshi Omura; Hiroshi Tomoda
Structure and total synthesis of fungal calpinactam, a new antimycobacterial agent.
Organic letters 2010;12(3):432-5.
2010: Junji Inokoshi; Yoichi Takagi; Ryuji Uchida; Rokuro Masuma; Satoshi Omura; Hiroshi Tomoda
Production of a new type of amidepsine with a sugar moiety by static fermentation of Humicola sp. FO-2942.
The Journal of antibiotics 2010;63(1):9-16.
2009: Daisuke Matsuda; Taichi Ohshiro; Mio Ohba; Wei Jiang; Bin Hong; Shuyi Si; Hiroshi Tomoda
The molecular target of rubimaillin in the inhibition of lipid droplet accumulation in macrophages.
Biological & pharmaceutical bulletin 2009;32(8):1317-20.
2009: Hiroyuki Yamazaki; Kenichi Nonaka; Rokuro Masuma; Satoshi Omura; Hiroshi Tomoda
Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2: I. Taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 2009;62(8):431-4.
2009: Hiroyuki Yamazaki; Satoshi Omura; Hiroshi Tomoda
Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2 II. Structure elucidation.
The Journal of antibiotics 2009;62(8):435-7.
2009: Taichi Ohshiro; Daisuke Matsuda; Kenichiro Nagai; Takayuki Doi; Toshiaki Sunazuka; Takashi Takahashi; Lawrence Lee Rudel; Satoshi Omura; Hiroshi Tomoda
The selectivity of beauveriolide derivatives in inhibition toward the two isozymes of acyl-CoA: cholesterol acyltransferase.
Chemical & pharmaceutical bulletin 2009;57(4):377-81.
2009: Hiroyuki Yamazaki; Satoshi Omura; Hiroshi Tomoda
Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation.
The Journal of antibiotics 2009;62(4):207-11.
2009: Hiroyuki Yamazaki; Kakeru Kobayashi; Daisuke Matsuda; Kenichi Nonaka; Rokuro Masuma; Satoshi Omura; Hiroshi Tomoda
Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1: I. Taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 2009;62(4):195-200.
2008: Kent Sakai; Satoshi Ohte; Taichi Ohshiro; Daisuke Matsuda; Rokuro Masuma; Lawrence L Rudel; Hiroshi Tomoda
Selective inhibition of acyl-CoA:cholesterol acyltransferase 2 isozyme by flavasperone and sterigmatocystin from Aspergillus species.
The Journal of antibiotics 2008;61(9):568-72.
2008: Takashi Fukuda; Yoko Hasegawa; Yasunari Sakabe; Hiroshi Tomoda; Satoshi Omura
Citrinamides, new potentiators of antifungal miconazole activity, produced by Penicillium sp. FKI-1938.
The Journal of antibiotics 2008;61(9):550-5.
2008: Nobuhiro Koyama; Kakeru Kobayashi; Hiroyuki Yamazaki; Hiroshi Tomoda
Inhibition of lipid droplet accumulation in mouse macrophages by stemphone derivatives.
The Journal of antibiotics 2008;61(8):509-14.
2008: Taichi Ohshiro; Satoshi Ohte; Daisuke Matsuda; Masaki Ohtawa; Tohru Nagamitsu; Toshiaki Sunazuka; Yoshihiro Harigaya; Lawrence L Rudel; Satoshi Omura; Hiroshi Tomoda
Selectivity of pyripyropene derivatives in inhibition toward acyl-CoA:cholesterol acyltransferase 2 isozyme.
The Journal of antibiotics 2008;61(8):503-8.
2008: Kenichiro Nagai; Takayuki Doi; Taichi Ohshiro; Toshiaki Sunazuka; Hiroshi Tomoda; Takashi Takahashi; Satoshi Omura
Synthesis and biological evaluation of a focused library of beauveriolides.
Bioorganic & medicinal chemistry letters 2008;18(15):4397-400.
2008: Hiroyuki Yamazaki; Nobuhiro Koyama; Satoshi Omura; Hiroshi Tomoda
Structure-activity relationships of stemphones, potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus.
The Journal of antibiotics 2008;61(7):426-41.
2008: Daisuke Matsuda; Ichiji Namatame; Taichi Ohshiro; Shun Ishibashi; Satoshi Omura; Hiroshi Tomoda
Anti-atherosclerotic activity of triacsin C, an acyl-CoA synthetase inhibitor.
The Journal of antibiotics 2008;61(5):318-21.
2008: Yasuhiro Kojima; Toshiaki Sunazuka; Kenichiro Nagai; Khachatur Julfakyan; Takashi Fukuda; Hiroshi Tomoda; Satoshi Omura
Total synthesis of malformin C, an inhibitor of bleomycin-induced G2 arrest.
The Journal of antibiotics 2008;61(5):297-302.
2008: Atsushi Fukumoto; Yong-Pil Kim; Hideaki Hanaki; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Cyslabdan, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Streptomyces sp. K04-0144. II. Biological activities.
The Journal of antibiotics 2008;61(1):7-10.
2008: Atsushi Fukumoto; Yong-Pil Kim; Atsuko Matsumoto; Yoko Takahashi; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Cyslabdan, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Streptomyces sp. K04-0144. I. Taxonomy, fermentation, isolation and structural elucidation.
The Journal of antibiotics 2008;61(1):1-6.
2007: Kazuro Shiomi; Hiroko Hatano; Hiromi Morimoto; Hideaki Ui; Kimitoshi Sakamoto; Kiyoshi Kita; Hiroshi Tomoda; Eun Woo Lee; Tae-Ryeon Heo; Hirokazu Kawagishi; Satoshi Omura
Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum.
Planta medica 2007;73(14):1478-81.
2007: Yoko Hasegawa; Takashi Fukuda; Keiichi Hagimori; Hiroshi Tomoda; Satoshi Omura
Tensyuic acids, new antibiotics produced by Aspergillus niger FKI-2342.
Chemical & pharmaceutical bulletin 2007;55(9):1338-41.
2007: Keiichi Hagimori; Takashi Fukuda; Yoko Hasegawa; Satoshi Omura; Hiroshi Tomoda
Fungal malformins inhibit bleomycin-induced G2 checkpoint in Jurkat cells.
Biological & pharmaceutical bulletin 2007;30(8):1379-83.
2007: Taichi Ohshiro; Lawrence L Rudel; Satoshi Omura; Hiroshi Tomoda
Selectivity of microbial acyl-CoA: cholesterol acyltransferase inhibitors toward isozymes.
The Journal of antibiotics 2007;60(1):43-51.
2006: Hideaki Ui; Kazuro Shiomi; Hideaki Suzuki; Hiroko Hatano; Hiromi Morimoto; Yuichi Yamaguchi; Rokuro Masuma; Toshiaki Sunazuka; Hiroyuki Shimamura; Kimitoshi Sakamoto; Kiyoshi Kita; Hideto Miyoshi; Hiroshi Tomoda; Satoshi Omura
Verticipyrone, a new NADH-fumarate reductase inhibitor, produced by Verticillium sp. FKI-1083.
The Journal of antibiotics 2006;59(12):785-90.
2006: Takashi Fukuda; Yasunari Sakabe; Hiroshi Tomoda; Satoshi Omura
Fungal citridone D having a novel phenylfuropyridine skeleton.
Chemical & pharmaceutical bulletin 2006;54(12):1659-61.
2006: Ryuji Uchida; Rie Imasato; Hiroshi Tomoda; Satoshi Omura
Yaequinolones, new insecticidal antibiotics produced by Penicillium sp. FKI-2140. II. Structural elucidation.
The Journal of antibiotics 2006;59(10):652-8.
2006: Ryuji Uchida; Rie Imasato; Yuichi Yamaguchi; Rokuro Masuma; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Yaequinolones, new insecticidal antibiotics produced by Penicillium sp. FKI-2140. I. Taxonomy, fermentation, isolation and biological activity.
The Journal of antibiotics 2006;59(10):646-51.
2006: Taichi Ohshiro; Ichiji Namatame; Kenichiro Nagai; Takafumi Sekiguchi; Takayuki Doi; Takashi Takahashi; Kazuaki Akasaka; Lawrence L Rudel; Hiroshi Tomoda; Satoshi Omura
Absolute stereochemistry of fungal beauveriolide III and ACAT inhibitory activity of four stereoisomers.
The Journal of organic chemistry 2006;71(20):7643-9.
2006: Hideaki Ui; Kazuro Shiomi; Hideaki Suzuki; Hiroko Hatano; Hiromi Morimoto; Yuichi Yamaguchi; Rokuro Masuma; Kimitoshi Sakamoto; Kiyoshi Kita; Hideto Miyoshi; Hiroshi Tomoda; Haruo Tanaka; Satoshi Omura
Paecilaminol, a new NADH-fumarate reductase inhibitor, produced by Paecilomyces sp. FKI-0550.
The Journal of antibiotics 2006;59(9):591-6.
2006: Takashi Fukuda; Yoko Hasegawa; Keiichi Hagimori; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Satoshi Omura
Tensidols, new potentiators of antifungal miconazole activity, produced by Aspergillus niger FKI-2342.
The Journal of antibiotics 2006;59(8):480-5.
2006: Ryuji Uchida; Hiroshi Tomoda; Satoshi Omura
Biosynthesis of sespendole.
The Journal of antibiotics 2006;59(5):298-302.
2006: Taichi Ohshiro; Ichiji Namatame; Eun Woo Lee; Hirokazu Kawagishi; Hiroshi Tomoda
Molecular target of decursins in the inhibition of lipid droplet accumulation in macrophages.
Biological & pharmaceutical bulletin 2006;29(5):981-4.
2006: Ryuji Uchida; Yong-Pil Kim; Ichiji Namatame; Hiroshi Tomoda; Satoshi Omura
Sespendole, a new inhibitor of lipid droplet synthesis in macrophages, produced by Pseudobotrytis terrestris FKA-25.
The Journal of antibiotics 2006;59(2):93-7.
2006: Kenichiro Nagai; Takayuki Doi; Takafumi Sekiguchi; Ichiji Namatame; Toshiaki Sunazuka; Hiroshi Tomoda; Satoshi Omura; Takashi Takahashi
Synthesis and biological evaluation of a beauveriolide analogue library.
Journal of combinatorial chemistry 2006;8(1):103-9.
2005: Ryuji Uchida; Rie Imasato; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Yaequinolones J1 and J2, novel insecticidal antibiotics from Penicillium sp. FKI-2140.
Organic letters 2005;7(25):5701-4.
2005: Ryuji Uchida; Rie Imasato; Yuichi Yamaguchi; Rokuro Masuma; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
New insecticidal antibiotics, hydroxyfungerins A and B, produced by Metarhizium sp. FKI-1079.
The Journal of antibiotics 2005;58(12):804-9.
2005: Nobuhiro Koyama; Tomoko Nagahiro; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Satoshi Omura
Stemphones, novel potentiators of imipenem activity against methicillin-resistant staphylococcus aureus, produced by Aspergillus sp. FKI-2136.
The Journal of antibiotics 2005;58(11):695-703.
2005: Akiko Kageyama; Yoko Takahashi; Tamae Seki; Hiroshi Tomoda; Satoshi Omura
Oryzihumus leptocrescens gen. nov., sp. nov.
International journal of systematic and evolutionary microbiology 2005;55(Pt 6):2555-9.
2005: Taichi Ohshiro; Ichiji Namatame; Kana Ochiai; Hirokazu Kawagishi; Hiroshi Tomoda
Inhibition of lipid droplet accumulation in macrophages by triterpenoids produced from Torametes orientaris.
Biological & pharmaceutical bulletin 2005;28(10):1925-7.
2005: Masaaki Shibuya; Barry B Snider; Yuichi Sakano; Hiroshi Tomoda; Satoshi Omura; Yutaka Ebizuka
Revised structures of epohelmins A and B isolated as lanosterol synthase inhibitors from a fungal strain FKI-0929.
The Journal of antibiotics 2005;58(9):599-601.
2005: Ryuji Uchida; Rie Imasato; Yuichi Yamaguchi; Rokuro Masuma; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
New sesquicillins, insecticidal antibiotics produced by Albophoma sp. FKI-1778.
The Journal of antibiotics 2005;58(6):397-404.
2005: Nobuhiro Koyama; Tomoko Nagahiro; Yuichi Yamaguchi; Taichi Ohshiro; Rokuro Masuma; Hiroshi Tomoda; Satoshi Omura
Spylidone, a novel inhibitor of lipid droplet accumulation in mouse macrophages produced by Phoma sp. FKI-1840.
The Journal of antibiotics 2005;58(5):338-45.
2005: Takashi Fukuda; Hiroshi Tomoda; Satoshi Omura
Citridones, new potentiators of antifungal miconazole activity, produced by Penicillium sp. FKI-1938. II. Structure elucidation.
The Journal of antibiotics 2005;58(5):315-21.
2005: Takashi Fukuda; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Satoshi Omura
Citridones, new potentiators of antifungal miconazole activity, produced by Penicillium sp. FKI-1938. I. Taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 2005;58(5):309-14.
2005: Takashi Fukuda; Atsuko Matsumoto; Yoko Takahashi; Hiroshi Tomoda; Satoshi Omura
Phenatic acids A and B, new potentiators of antifungal miconazole activity produced by Streptomyces sp. K03-0132.
The Journal of antibiotics 2005;58(4):252-9.
2005: Keiko Goto; Tomohiro Asai; Shuntaro Hara; Ichiji Namatame; Hiroshi Tomoda; Mamoru Ikemoto; Naoto Oku
Enhanced antitumor activity of xanthohumol, a diacylglycerol acyltransferase inhibitor, under hypoxia.
Cancer letters 2005;219(2):215-22.
2005: Kazuro Shiomi; Kenji Hatae; Hiroko Hatano; Atsuko Matsumoto; Yoko Takahashi; Cheng-Lin Jiang; Hiroshi Tomoda; Susumu Kobayashi; Haruo Tanaka; Satoshi Omura
A new antibiotic, antimycin Ag, produced by Streptomyces sp. K01-0031.
The Journal of antibiotics 2005;58(1):74-8.
2005: Kazuro Shiomi; Ryosuke Matsui; Miki Isozaki; Harumi Chiba; Takahiro Sugai; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Tomoko Chiba; Hua Yan; Yoshihiro Kitamura; Wataru Sugiura; Satoshi Omura; Haruo Tanaka
Fungal phenalenones inhibit HIV-1 integrase.
The Journal of antibiotics 2005;58(1):65-8.
2005: Kazuro Shiomi; Hideaki Ui; Hideaki Suzuki; Hiroko Hatano; Tohru Nagamitsu; Daisuke Takano; Hiroko Miyadera; Tetsuo Yamashita; Kiyoshi Kita; Hideto Miyoshi; Achim Harder; Hiroshi Tomoda; Satoshi Omura
A gamma-lactone form nafuredin, nafuredin-gamma, also inhibits helminth complex I.
The Journal of antibiotics 2005;58(1):50-5.
2004: Masayoshi Arai; Yukio Koizumi; Hitoshi Sato; Takumi Kawabe; Masashi Suganuma; Hidetaka Kobayashi; Hiroshi Tomoda; Satoshi Omura
Boromycin abrogates bleomycin-induced G2 checkpoint.
The Journal of antibiotics 2004;57(10):662-8.
2004: Duy H Hua; Xiaodong Huang; Yi Chen; Srinivas K Battina; Masafumi Tamura; Sang K Noh; Sung I Koo; Ichiji Namatame; Hiroshi Tomoda; Elisabeth M Perchellet; Jean-Pierre H Perchellet
Total syntheses of (+)-chloropuupehenone and (+)-chloropuupehenol and their analogues and evaluation of their bioactivities.
The Journal of organic chemistry 2004;69(18):6065-78.
2004: Yuichi Sakano; Masaaki Shibuya; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Satoshi Omura; Yutaka Ebizuka
Epohelmins A and B, novel lanosterol synthase inhibitors from a fungal strain FKI-0929.
The Journal of antibiotics 2004;57(9):564-8.
2004: Yukio Koizumi; Masayoshi Arai; Hiroshi Tomoda; Satoshi Omura
Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization.
Biochimica et biophysica acta 2004;1693(1):47-55.
2004: Yukio Koizumi; Masayoshi Arai; Hiroshi Tomoda; Satoshi Omura
Fungerin, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of microtubule polymerization.
The Journal of antibiotics 2004;57(7):415-20.
2004: Kazuhiko Otoguro; Aki Ishiyama; Miyuki Kobayashi; Hitomi Sekiguchi; Takashi Izuhara; Toshiaki Sunazuka; Hiroshi Tomoda; Haruki Yamada; Satoshi Omura
In vitro and in vivo antimalarial activities of a carbohydrate antibiotic, prumycin, against drug-resistant strains of Plasmodia.
The Journal of antibiotics 2004;57(6):400-2.
2004: Masayoshi Arai; Hitoshi Sato; Hidetaka Kobayashi; Masashi Suganuma; Takumi Kawabe; Hiroshi Tomoda; Satoshi Omura
Selective inhibition of bleomycin-induced G2 cell cycle checkpoint by simaomicin alpha.
Biochemical and biophysical research communications 2004;317(3):817-22.
2004: Hiroshi Tomoda; Naomi Ohbayashi; Yuko Morikawa; Hidetoshi Kumagai; Satoshi Omura
Binding site for fungal beta-lactone hymeglusin on cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase.
Biochimica et biophysica acta 2004;1636(1):22-8.
2004: Takashi Fukuda; Masayoshi Arai; Hiroshi Tomoda; Satoshi Omura
New beauvericins, potentiators of antifungal miconazole activity, Produced by Beauveria sp. FKI-1366. II. Structure elucidation.
The Journal of antibiotics 2004;57(2):117-24.
2004: Takashi Fukuda; Masayoshi Arai; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Satoshi Omura
New beauvericins, potentiators of antifungal miconazole activity, Produced by Beauveria sp. FKI-1366. I. Taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 2004;57(2):110-6.
2004: Ichiji Namatame; Hiroshi Tomoda; Shun Ishibashi; Satoshi Omura
Antiatherogenic activity of fungal beauveriolides, inhibitors of lipid droplet accumulation in macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(3):737-42.
2004: Daisuke Matsuda; Ichiji Namatame; Hiroshi Tomoda; Susumu Kobayashi; Rainer Zocher; Horst Kleinkauf; Satoshi Omura
New beauveriolides produced by amino acid-supplemented fermentation of Beauveria sp. FO-6979.
The Journal of antibiotics 2004;57(1):1-9.
2003: Yuichi Sakano; Masaaki Shibuya; Atsuko Matsumoto; Yoko Takahashi; Hiroshi Tomoda; Satoshi Omura; Yutaka Ebizuka
Lanopylins A1, B1, A2 and B2, novel lanosterol synthase inhibitors from Streptomyces sp. K99-5041.
The Journal of antibiotics 2003;56(10):817-26.
2003: Yōko Takahashi; Shogo Katoh; Noriyasu Shikura; Hiroshi Tomoda; Satoshi Omura
Superoxide dismutase produced by soil bacteria increases bacterial colony growth from soil samples.
The Journal of general and applied microbiology 2003;49(4):263-6.
2003: Kazuhiko Otoguro; Hideaki Ui; Aki Ishiyama; Miyuki Kobayashi; Hideaki Togashi; Yoko Takahashi; Rokuro Masuma; Haruo Tanaka; Hiroshi Tomoda; Haruki Yamada; Satoshi Omura
In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia.
The Journal of antibiotics 2003;56(8):727-9.
2003: Kazunobu Yamamoto; Hiroko Hatano; Masayoshi Arai; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Structure elucidation of new monordens produced by Humicola sp. FO-2942.
The Journal of antibiotics 2003;56(6):533-8.
2003: Masayoshi Arai; Kazunobu Yamamoto; Ichiji Namatame; Hiroshi Tomoda; Satoshi Omura
New monordens produced by amidepsine-producing fungus Humicola sp. FO-2942.
The Journal of antibiotics 2003;56(6):526-32.
2003: Takashi Fukuda; Yong-Pil Kim; Kousuke Iizima; Hiroshi Tomoda; Satoshi Omura
Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278. II. Structure elucidation.
The Journal of antibiotics 2003;56(5):454-8.
2003: Yong-Pil Kim; Hiroshi Tomoda; Kousuke Iizima; Takashi Fukuda; Atsuko Matsumoto; Yoko Takahashi; Satoshi Omura
Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278. I. Taxonomy, fermentation, isolation and biological properties.
The Journal of antibiotics 2003;56(5):448-53.
2003: Hiroko Miyadera; Kazuro Shiomi; Hideaki Ui; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Hideto Miyoshi; Arihiro Osanai; Kiyoshi Kita; Satoshi Omura
Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase).
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):473-7.
2003: Hiroshi Tomoda; Noriko Tabata; Yukako Ohyama; Satoshi Omura
Core structure in roselipins essential for eliciting inhibitory activity against diacylglycerol acyltransferase.
The Journal of antibiotics 2003;56(1):24-9.
2002: Ichiji Namatame; Daisuke Matsuda; Hiroshi Tomoda; Yuichi Yamaguchi; Rokuro Masuma; Susumu Kobayashi; Satoshi Omura
Selective production of fungal beauveriolide I or III by fermentation in amino acid-supplemented media.
The Journal of antibiotics 2002;55(12):1048-52.
2002: Hiroshi Tomoda; Masayoshi Arai; Nobuhiro Koyama; Hidenori Matsui; Satoshi O mura; Rika Obata; Yuan C Lee
Purification of Shiga-like toxin 1 by pigeon egg white glycoproteins immobilized on Sepharose gels.
Analytical biochemistry 2002;311(1):50-6.
2002: Kazuro Shiomi; Kenji Hatae; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Susumu Kobayashi; Satoshi Omura
New antibiotics miyakamides produced by a fungus.
The Journal of antibiotics 2002;55(11):952-61.
2002: Masayoshi Arai; Hiroshi Tomoda; Takako Okuda; Haiyan Wang; Noriko Tabata; Rokuro Masuma; Yuichi Yamaguchi; Satoshi Omura
Funicone-related compounds, potentiators of antifungal miconazole activity, produced by Talaromycesflavus FKI-0076.
The Journal of antibiotics 2002;55(2):172-80.
2001: R Uchida; Hiroshi Tomoda; Masayoshi Arai; Satoshi Omura
Chlorogentisylquinone, a new neutral sphingomyelinase inhibitor, produced by a marine fungus.
The Journal of antibiotics 2001;54(11):882-9.
2001: H Zhang; Hiroshi Tomoda; Noriko Tabata; H Miura; M Namikoshi; Yuichi Yamaguchi; Rokuro Masuma; Satoshi Omura
Cladospolide D, a new 12-membered macrolide antibiotic produced by Cladosporium sp. FT-0012.
The Journal of antibiotics 2001;54(8):635-41.
2000: Mun-Chual Rho; Masahiko Hayashi; Akiko Fukami; R Obata; Toshiaki Sunazuka; Hiroshi Tomoda; Kanki Komiyama; Satoshi Omura
Reversal of multidrug resistance by 7-O-benzoylpyripyropene A in multidrug-resistant tumor cells.
The Journal of antibiotics 2000;53(10):1201-6.
2000: R Obata; Toshiaki Sunazuka; Kazuhiko Otoguro; Hiroshi Tomoda; Yoshihiro Harigaya; Satoshi Omura
Synthetic conversion of ACAT inhibitor to acetylcholinesterase inhibitor.
Bioorganic & medicinal chemistry letters 2000;10(12):1315-6.
2000: R Obata; Toshiaki Sunazuka; Yoshihiro Harigaya; Masahiko Hayashi; Mun-Chual Rho; Hiroshi Tomoda; Satoshi Omura
Structure-activity relationships study of pyripyropenes: reversal of cancer cell multidrug resistance.
The Journal of antibiotics 2000;53(4):422-5.
2000: Ichiji Namatame; Hiroshi Tomoda; M Arai; Satoshi Omura
Effect of fungal metabolites cytochalasans on lipid droplet formation in mouse macrophages.
The Journal of antibiotics 2000;53(1):19-25.
1999: Noriko Tabata; Hiroshi Tomoda; Satoshi Omura
Ferroverdins, inhibitors of cholesteryl ester transfer protein produced by Streptomyces sp. WK-5344. II. Structure elucidation.
The Journal of antibiotics 1999;52(12):1108-13.
1999: Hiroshi Tomoda; Noriko Tabata; M Shinose; Y Takahashi; H B Woodruff; Satoshi Omura
Ferroverdins, inhibitors of cholesteryl ester transfer protein produced by Streptomyces sp. WK-5344. I. Production, isolation and biological properties.
The Journal of antibiotics 1999;52(12):1101-7.
1999: Hiroshi Tomoda; N Ohbayashi; H Kumagai; H Hashizume; Toshiaki Sunazuka; Satoshi Omura
Differential inhibition of HMG-CoA synthase and pancreatic lipase by the specific chiral isomers of beta-lactone DU-6622.
Biochemical and biophysical research communications 1999;265(2):536-40.
1999: Noriko Tabata; Hiroshi Tomoda; Yuichi Yamaguchi; Rokuro Masuma; M J Bamberger; Satoshi Omura
Inhibition of cholesteryl ester transfer protein by fungal metabolites, L681,512.
The Journal of antibiotics 1999;52(11):1042-5.
1999: Hiroshi Tomoda; Ichiji Namatame; Noriko Tabata; K Kawaguchi; SY Si; Satoshi Omura
Structure elucidation of fungal phenochalasins, novel inhibitors of lipid droplet formation in mouse macrophages.
The Journal of antibiotics 1999;52(10):857-61.
1999: Hiroshi Tomoda; Ichiji Namatame; SY Si; K Kawaguchi; Rokuro Masuma; M Namikoshi; Satoshi Omura
Phenochalasins, inhibitors of lipid droplet formation in mouse macrophages, produced by Phomopsis sp. FT-0211.
The Journal of antibiotics 1999;52(10):851-6.
1999: Noriko Tabata; Y Ohyama; Hiroshi Tomoda; T Abe; M Namikoshi; Satoshi Omura
Structure elucidation of roselipins, inhibitors of diacylglycerol acyltransferase produced by Gliocladium roseum KF-1040.
The Journal of antibiotics 1999;52(9):815-26.
1999: Hiroshi Tomoda; Y Ohyama; T Abe; Noriko Tabata; M Namikoshi; Yuichi Yamaguchi; Rokuro Masuma; Satoshi Omura
Roselipins, inhibitors of diacylglycerol acyltransferase, produced by Gliocladium roseum KF-1040.
The Journal of antibiotics 1999;52(8):689-94.
1999: Satoshi Omura; Hiroshi Tomoda; Noriko Tabata; Y Ohyama; T Abe; M Namikoshi
Roselipins, novel fungal metabolites having a highly methylated fatty acid modified with a mannose and an arabinitol.
The Journal of antibiotics 1999;52(6):586-9.
1999: R Uchida; Hiroshi Tomoda; Y Dong; Satoshi Omura
Alutenusin, a specific neutral sphingomyelinase inhibitor, produced by Penicillium sp. FO-7436.
The Journal of antibiotics 1999;52(6):572-4.
1999: Hiroshi Tomoda; C Matsushima; Noriko Tabata; Ichiji Namatame; H Tanaka; M J Bamberger; H Arai; M Fukazawa; K Inoue; Satoshi Omura
Structure-specific inhibition of cholesteryl ester transfer protein by azaphilones.
The Journal of antibiotics 1999;52(2):160-70.
1999: Ichiji Namatame; Hiroshi Tomoda; Hiroyuki Arai; K Inoue; Satoshi Omura
Complete inhibition of mouse macrophage-derived foam cell formation by triacsin C.
Journal of biochemistry 1999;125(2):319-27.
1999: Noriko Tabata; Hiroshi Tomoda; H Zhang; R Uchida; Satoshi Omura
Zelkovamycin, a new cyclic peptide antibiotic from Streptomyces sp. K96-0670. II. Structure elucidation.
The Journal of antibiotics 1999;52(1):34-9.
1999: H Zhang; Hiroshi Tomoda; Noriko Tabata; Masako Oohori; M Shinose; Y Takahashi; Satoshi Omura
Zelkovamycin, a new cyclic peptide antibiotic from Streptomyces sp. K96-0670. I. Production, isolation and biological properties.
The Journal of antibiotics 1999;52(1):29-33.
1999: Ichiji Namatame; Hiroshi Tomoda; Noriko Tabata; SY Si; Satoshi Omura
Structure elucidation of fungal beauveriolide III, a novel inhibitor of lipid droplet formation in mouse macrophages.
The Journal of antibiotics 1999;52(1):7-12.
1999: Ichiji Namatame; Hiroshi Tomoda; SY Si; Y Yamaguchi; Rokuro Masuma; Satoshi Omura
Beauveriolides, specific inhibitors of lipid droplet formation in mouse macrophages, produced by Beauveria sp. FO-6979.
The Journal of antibiotics 1999;52(1):1-6.
1998: Noriko Tabata; Hiroshi Tomoda; Satoshi Omura
Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637. II. Structure elucidation of erabulenols A and B.
The Journal of antibiotics 1998;51(7):624-8.
1998: Hiroshi Tomoda; Noriko Tabata; Rokuro Masuma; SY Si; Satoshi Omura
Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637. I.Production, isolation and biological properties.
The Journal of antibiotics 1998;51(7):618-23.
1997: N Tabata; M Ito; Hiroshi Tomoda; Satoshi Omura
Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus.
Phytochemistry 1997;46(4):683-7.
1997: Jean-Pierre H Perchellet; SW Newell; JB Ladesich; Elisabeth M Perchellet; Yi Chen; Duy H Hua; Susan L Kraft; Randall J Basaraba; S Omura; Hiroshi Tomoda
Antitumor activity of novel tricyclic pyrone analogs in murine leukemia cells in vitro.
Anticancer research 1997;17(4A):2427-34.
1997: R Obata; Toshiaki Sunazuka; Z Tian; Hiroshi Tomoda; Yoshihiro Harigaya; Satoshi Omura
Chemical modification and structure-activity relationships of pyripyropenes. 3. Synthetic conversion of pyridine-pyrone moiety.
The Journal of antibiotics 1997;50(3):229-36.
1996: R Obata; Toshiaki Sunazuka; Y Kato; Hiroshi Tomoda; Yoshihiro Harigaya; Satoshi Omura
Chemical modification and structure-activity relationships of pyripyropenes. 2. 1,11-Cyclic analogs.
The Journal of antibiotics 1996;49(11):1149-56.
1996: R Obata; Toshiaki Sunazuka; Z Li; Z Tian; Yoshihiro Harigaya; Noriko Tabata; Hiroshi Tomoda; Satoshi Omura
Chemical modification and structure-activity relationships of pyripyropenes. 1. Modification at the four hydroxyl groups.
The Journal of antibiotics 1996;49(11):1133-48.
1996: H Miura; Hiroshi Tomoda; K Miura; K Takishima; Satoshi Omura
Lactacystin increases LDL receptor level on HepG2 cells.
Biochemical and biophysical research communications 1996;227(3):684-7.
1996: Hiroshi Tomoda; Yuichi Yamaguchi; Noriko Tabata; T Kobayashi; Rokuro Masuma; H Tanaka; Satoshi Omura
Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969.
The Journal of antibiotics 1996;49(9):929-31.
1996: Hiroshi Tomoda; Noriko Tabata; D J Yang; Ichiji Namatame; H Tanaka; Satoshi Omura; T Kaneko
Pyripyropenes, novel ACAT inhibitors produced by Aspergillus fumigatus. IV. Structure elucidation of pyripyropenes M to R.
The Journal of antibiotics 1996;49(3):292-8.
1996: Noriko Tabata; Hiroshi Tomoda; Y Iwai; Satoshi Omura
Xanthoquinodin B3, a new anticoccidial agent produced by Humicola sp. FO-888.
The Journal of antibiotics 1996;49(3):267-71.
1996: D J Yang; Hiroshi Tomoda; Noriko Tabata; Rokuro Masuma; Satoshi Omura
New isochromophilones VII and VIII produced by Penicillium sp. FO-4164.
The Journal of antibiotics 1996;49(3):223-9.
1995: Hiroshi Tomoda; Noriko Tabata; M Ito; Satoshi Omura
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C.
The Journal of antibiotics 1995;48(9):942-7.
1995: Hiroshi Tomoda; M Ito; Noriko Tabata; Rokuro Masuma; Yuichi Yamaguchi; Satoshi Omura
Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties.
The Journal of antibiotics 1995;48(9):937-41.
1995: Hiroshi Tomoda; Noriko Tabata; D J Yang; H Takayanagi; Satoshi Omura
Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. III. Production, isolation and structure elucidation of new components.
The Journal of antibiotics 1995;48(8):793-804.
1995: R Obata; Toshiaki Sunazuka; Z Li; Hiroshi Tomoda; Satoshi Omura
Structure-activity relationships of pyripyropenes fungal acyl-CoA: cholesterol acyltransferase inhibitors.
The Journal of antibiotics 1995;48(7):749-50.
1995: N Arai; Kazuro Shiomi; Hiroshi Tomoda; Noriko Tabata; D J Yang; Rokuro Masuma; T Kawakubo; Satoshi Omura
Isochromophilones III-VI, inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium multicolor FO-3216.
The Journal of antibiotics 1995;48(7):696-702.
1995: Hiroshi Tomoda; Noriko Tabata; D J Yang; H Takayanagi; H Nishida; Satoshi Omura; T Kaneko
Pyripyropenes, Novel ACAT inhibitors produced by Aspergillus fumigatus. III. Structure elucidation of pyripyropenes E to L.
The Journal of antibiotics 1995;48(6):495-503.
1995: Noriko Tabata; Hiroshi Tomoda; Y Iwai; Satoshi Omura
Arohynapene D, a new anticoccidial agent produced by Penicillium sp. FO-2295.
The Journal of antibiotics 1995;48(1):83-4.
1995: Noriko Tabata; Hiroshi Tomoda; Rokuro Masuma; Y Iwai; Satoshi Omura
Fudecalone, a new anticoccidial agent produced by Penicillium sp. FO-2030.
The Journal of antibiotics 1995;48(1):53-8.
1995: X H Huang; H Nishida; Hiroshi Tomoda; Noriko Tabata; Kazuro Shiomi; D J Yang; H Takayanagi; Satoshi Omura
Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. II. Structure elucidation of terpendoles A, B, C and D.
The Journal of antibiotics 1995;48(1):5-11.
1995: X H Huang; Hiroshi Tomoda; H Nishida; Rokuro Masuma; Satoshi Omura
Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. I. Production, isolation and biological properties.
The Journal of antibiotics 1995;48(1):1-4.
1994: Kazuro Shiomi; K Haneda; Hiroshi Tomoda; Y Iwai; Satoshi Omura
Cytosaminomycins, new anticoccidial agents produced by Streptomyces sp. KO-8119. II. Structure elucidation of cytosaminomycins A, B, C and D.
The Journal of antibiotics 1994;47(7):782-6.
1994: K Haneda; M Shinose; A Seino; Noriko Tabata; Hiroshi Tomoda; Y Iwai; Satoshi Omura
Cytosaminomycins, new anticoccidial agents produced by Streptomyces sp. KO-8119. I. Taxonomy, production, isolation and physico-chemical and biological properties.
The Journal of antibiotics 1994;47(7):774-81.
1994: Y K Kim; Hiroshi Tomoda; H Nishida; Toshiaki Sunazuka; R Obata; Satoshi Omura
Pyripyropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus. II. Structure elucidation of pyripyropenes A, B, C and D.
The Journal of antibiotics 1994;47(2):154-62.
1994: Hiroshi Tomoda; Y K Kim; H Nishida; Rokuro Masuma; Satoshi Omura
Pyripyropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus. I. Production, isolation, and biological properties.
The Journal of antibiotics 1994;47(2):148-53.
1994: Rokuro Masuma; Noriko Tabata; Hiroshi Tomoda; K Haneda; Y Iwai; Satoshi Omura
Arohynapenes A and B, new anticoccidial agents produced by Penicillium sp. Taxonomy, fermentation, and structure elucidation.
The Journal of antibiotics 1994;47(1):46-53.
1993: Noriko Tabata; Hiroshi Tomoda; Y Iwai; Satoshi Omura
Hynapenes A, B and C, new anticoccidial agents produced by Penicillium sp. II. Structure elucidation.
The Journal of antibiotics 1993;46(12):1854-8.
1993: Noriko Tabata; Hiroshi Tomoda; Rokuro Masuma; K Haneda; Y Iwai; Satoshi Omura
Hynapenes A, B and C, new anticoccidial agents produced by Penicillium sp. I. Production, isolation and physico-chemical and biological properties.
The Journal of antibiotics 1993;46(12):1849-53.
1993: Hiroshi Tomoda; Satoshi Omura
[Triacsins, inhibitors of fatty acid activating enzyme].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(11):1929-37.
1993: Toshiaki Sunazuka; Noriko Tabata; T Nagamitsu; Hiroshi Tomoda; Satoshi Omura
Synthesis of diolmycin analogs and their anticoccidial activities.
The Journal of antibiotics 1993;46(7):1178-80.
1993: Noriko Tabata; Toshiaki Sunazuka; Hiroshi Tomoda; T Nagamitsu; Y Iwai; Satoshi Omura
Diolmycins, new anticoccidial agents produced by Streptomyces sp. II. Structure elucidation of diolmycins A1, A2, B1 and B2, and synthesis of diolmycin A1.
The Journal of antibiotics 1993;46(5):762-9.
1993: Noriko Tabata; Hiroshi Tomoda; Y Takahashi; K Haneda; Y Iwai; H B Woodruff; Satoshi Omura
Diolmycins, new anticoccidial agents produced by Streptomyces sp. I. Production, isolation and physico-chemical and biological properties.
The Journal of antibiotics 1993;46(5):756-61.
1993: Noriko Tabata; Y Suzumura; Hiroshi Tomoda; Rokuro Masuma; K Haneda; M Kishi; Y Iwai; Satoshi Omura
Xanthoquinodins, new anticoccidial agents produced by Humicola sp. Production, isolation and physico-chemical and biological properties.
The Journal of antibiotics 1993;46(5):749-55.
1993: Hiroshi Tomoda; Satoshi Omura
Lipid metabolism inhibitors of microbial origin.
The Kitasato archives of experimental medicine 1993;65 Suppl():1-12.
1992: H Nishida; X H Huang; Hiroshi Tomoda; Satoshi Omura
Glisoprenins, new inhibitors of acyl-CoA: cholesterol acyltransferase produced by Gliocladium sp. FO-1513. II. Structure elucidation of glisoprenins A and B.
The Journal of antibiotics 1992;45(10):1669-76.
1992: Hiroshi Tomoda; X H Huang; J Cao; H Nishida; R Nagao; S Okuda; H Tanaka; Satoshi Omura; H Arai; K Inoue
Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics.
The Journal of antibiotics 1992;45(10):1626-32.
1992: Hiroshi Tomoda; H Nishida; X H Huang; Rokuro Masuma; Y K Kim; Satoshi Omura
New cyclodepsipeptides, enniatins D, E and F produced by Fusarium sp. FO-1305.
The Journal of antibiotics 1992;45(8):1207-15.
1992: Hiroshi Tomoda; X H Huang; H Nishida; Rokuro Masuma; Y K Kim; Satoshi Omura
Glisoprenins, new inhibitors of acyl-CoA: cholesterol acyltransferase produced by Gliocladium sp. FO-1513. I. Production, isolation and physico-chemical and biological properties.
The Journal of antibiotics 1992;45(8):1202-6.
1992: Toshiaki Sunazuka; K Tsuzuki; H Kumagai; Hiroshi Tomoda; H Tanaka; H Nagashima; H Hashizume; Satoshi Omura
Synthesis of 1233A analogs and their inhibitory activity against hydroxymethylglutaryl coenzyme A synthase.
The Journal of antibiotics 1992;45(7):1139-47.
1992: H Kumagai; Hiroshi Tomoda; Satoshi Omura
Biosynthesis of antibiotic 1233A (F-244) and preparation of [14C]1233A.
The Journal of antibiotics 1992;45(4):563-7.
1991: Hiroshi Tomoda; K Igarashi; J C Cyong; Satoshi Omura
Evidence for an essential role of long chain acyl-CoA synthetase in animal cell proliferation. Inhibition of long chain acyl-CoA synthetase by triacsins caused inhibition of Raji cell proliferation.
The Journal of biological chemistry 1991;266(7):4214-9.
1991: H Nishida; Hiroshi Tomoda; J Cao; S Araki; S Okuda; Satoshi Omura
Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. III. Chemical modification of purpactin A.
The Journal of antibiotics 1991;44(2):152-9.
1991: H Nishida; Hiroshi Tomoda; J Cao; S Okuda; Satoshi Omura
Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. II. Structure elucidation of purpactins A, B and C.
The Journal of antibiotics 1991;44(2):144-51.
1991: Hiroshi Tomoda; H Nishida; Rokuro Masuma; J Cao; S Okuda; Satoshi Omura
Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. I. Production, isolation and physico-chemical and biological properties.
The Journal of antibiotics 1991;44(2):136-43.
1990: H Kumagai; H Nishida; N Imamura; Hiroshi Tomoda; Satoshi Omura; J Bordner
The structures of atpenins A4, A5 and B, new antifungal antibiotics produced by Penicillium sp.
The Journal of antibiotics 1990;43(12):1553-8.
1990: Hiroshi Tomoda; Satoshi Omura
New strategy for discovery of enzyme inhibitors: screening with intact mammalian cells or intact microorganisms having special functions.
The Journal of antibiotics 1990;43(10):1207-22.
1988: Y Tanaka; K Kimura; Y Komagata; K Tsuzuki; Hiroshi Tomoda; Satoshi Omura
Radioimmunoassay for erythromycin derivatives.
The Journal of antibiotics 1988;41(2):258-60.