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Linjiang Tong

Research Profile

Physiology

Cell Proliferation

Chemicals & Drugs

Anatomy

Living Beings

Genes & Molecular Sequences

Molecular Structure

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Phosphorylation

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Procedures

Drug Screening Assays, Antitumor

Disorders

Neovascularization, Pathologic

Co-author Network

Publications

TOP 3
Yuanfeng Zhou; Yi Chen; Meiyu Geng; Hualiang Jiang; Liping Lin; Cheng Luo; Yanyan Shen; Linjiang Tong; Yuanyuan Wang; Weiwei Wen; Yong Xi; Hua Xie; Jie Zhang; Jian Ding
AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.
Xiangqian Kong; Zeng Li; Zhongjie Liang; Hong Liu; Shien Liu; Junyan Lu; Ronen Marmorstein; Jie Qin; Geena Rajan; Linjiang Tong; Adina Vultur; Mingyue Zheng; Weiliang Zhu; Enguang Feng; Meenhard Herlyn; Hualiang Jiang; Cheng Luo
Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization.
Zhuo Chen; Xin Wang; Weiping Zhu; Xianwen Cao; Linjiang Tong; Honglin Li; Hua Xie; Yufang Xu; Shaoying Tan; Dong Kuang; Jian Ding; Xuhong Qian
Acenaphtho[1,2-b]pyrrole-based selective fibroblast growth factor receptors 1 (FGFR1) inhibitors: design, synthesis, and biological activity.

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All Publications

2012: Yuanfeng Zhou; Yi Chen; Meiyu Geng; Hualiang Jiang; Liping Lin; Cheng Luo; Yanyan Shen; Linjiang Tong; Yuanyuan Wang; Weiwei Wen; Yong Xi; Hua Xie; Jie Zhang; Jian Ding
AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.
Journal of cellular and molecular medicine 2012;16(10):2321-30.
2012: Xiangqian Kong; Zeng Li; Zhongjie Liang; Hong Liu; Shien Liu; Junyan Lu; Ronen Marmorstein; Jie Qin; Geena Rajan; Linjiang Tong; Adina Vultur; Mingyue Zheng; Weiliang Zhu; Enguang Feng; Meenhard Herlyn; Hualiang Jiang; Cheng Luo
Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization.
Organic & biomolecular chemistry 2012;10(36):7402-17.
2011: Zhuo Chen; Xin Wang; Weiping Zhu; Xianwen Cao; Linjiang Tong; Honglin Li; Hua Xie; Yufang Xu; Shaoying Tan; Dong Kuang; Jian Ding; Xuhong Qian
Acenaphtho[1,2-b]pyrrole-based selective fibroblast growth factor receptors 1 (FGFR1) inhibitors: design, synthesis, and biological activity.
Journal of medicinal chemistry 2011;54(11):3732-45.
2011: Caihua Zhu; Qin Chen; Zuoquan Xie; Jing Ai; Linjiang Tong; Jian Ding; Meiyu Geng
The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc.
Journal of molecular medicine (Berlin, Germany) 2011;89(3):279-89.
2011: Hua Xie; Yang Yang; Xiaowei Zhang; Mingyue Zheng; Jianping Zuo; Yi Chen; Zhuo Chen; Meiyu Geng; Hualiang Jiang; Xiaoyan Jiang; Yong Jiang; Liping Lin; Wenchao Qu; Xiaowei Ren; Linjiang Tong; Hua Wan; Jian Ding
AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo.
PloS one 2011;6(7):e21487.
2010: Xiaofeng Liu; Hua Xie; Cheng Luo; Linjiang Tong; Yi Wang; Ting Peng; Jian Ding; Hualiang Jiang; Honglin Li
Discovery and SAR of thiazolidine-2,4-dione analogues as insulin-like growth factor-1 receptor (IGF-1R) inhibitors via hierarchical virtual screening.
Journal of medicinal chemistry 2010;53(6):2661-5.
2009: Ya Wang; Yaoji Xuan; Ping Zhang; Xi Jiang; Zhenhua Ni; Linjiang Tong; Xiangshan Zhou; Liping Lin; Jian Ding; Yuanxing Zhang
Targeting expression of the catalytic domain of the kinase insert domain receptor (KDR) in the peroxisomes of Pichia pastoris.
FEMS yeast research 2009;9(5):732-41.
2008: Jingui Ma; Xianliang Xin; Linghua Meng; Linjiang Tong; Liping Lin; Meiyu Geng; Jian Ding
The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo.
PloS one 2008;3(11):e3774.
2007: Weihong Li; Yong Shao; Lihong Hu; Xiongwen Zhang; Yi Chen; Linjiang Tong; Chuan Li; Xu Shen; Jian Ding
BM6, a new semi-synthetic vinca alkaloid, exhibits its potent in vivo anti-tumor activities via its high binding affinity for tubulin and improved pharmacokinetic profiles.
Cancer biology & therapy 2007;6(5):787-94.
2005: Yunguang Tong; Xiongwen Zhang; Fang Tian; Yanghua Yi; Qiangzhi Xu; Ling Li; Linjiang Tong; Liping Lin; Jian Ding
Philinopside A, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects.
International journal of cancer. Journal international du cancer 2005;114(6):843-53.
2004: Yunguang Tong; Xiongwen Zhang; Weimin Zhao; Yixiang Zhang; Jingyu Lang; Yuhua Shi; Wenfu Tan; Meihong Li; Yongwei Zhang; Linjiang Tong; He Lu; Liping Lin; Jian Ding
Anti-angiogenic effects of Shiraiachrome A, a compound isolated from a Chinese folk medicine used to treat rheumatoid arthritis.
European journal of pharmacology 2004;494(2-3):101-9.