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Tanjun Tong

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Physiology

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Limin Han; Jun Chen; Hui Wang; Meng Wang; Pan Wang; Ganye Zhao; Tanjun Tong
Upregulation of SIRT1 by 17β-estradiol depends on ubiquitin-proteasome degradation of PPAR-γ mediated by NEDD4-1.
Qian Li; Cuicui Lv; Jingxuan Fu; Limin Han; Guodong Li; Pan Wang; Lixiang Xue; Yu Zhang; Tanjun Tong
FOXA1 mediates p16(INK4a) activation during cellular senescence.
Tianda Chen; Guodong Li; Na Li; Qian Li; Liwei Ma; Jing Niu; Jiamu Wang; Meng Wang; Lixiang Xue; Wenting Zhao; Xiaoxiao Cao; Tanjun Tong
The retinoblastoma protein selectively represses E2F1 targets via a TAAC DNA element during cellular senescence.

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All Publications

2013: Limin Han; Jun Chen; Hui Wang; Meng Wang; Pan Wang; Ganye Zhao; Tanjun Tong
Upregulation of SIRT1 by 17β-estradiol depends on ubiquitin-proteasome degradation of PPAR-γ mediated by NEDD4-1.
Protein & cell 2013;4(4):310-21.
2013: Qian Li; Cuicui Lv; Jingxuan Fu; Limin Han; Guodong Li; Pan Wang; Lixiang Xue; Yu Zhang; Tanjun Tong
FOXA1 mediates p16(INK4a) activation during cellular senescence.
The EMBO journal 2013;32(6):858-73.
2012: Tianda Chen; Guodong Li; Na Li; Qian Li; Liwei Ma; Jing Niu; Jiamu Wang; Meng Wang; Lixiang Xue; Wenting Zhao; Xiaoxiao Cao; Tanjun Tong
The retinoblastoma protein selectively represses E2F1 targets via a TAAC DNA element during cellular senescence.
The Journal of biological chemistry 2012;287(44):37540-51.
2012: Xiaotian Zhang; Junyue Xing; Jie Yi; Minqwei Yu; Myriam Gorospe; Zhenyun Liu; Yongfeng Shang; Hao Tang; Tanjun Tong; Wengong Wang
The tRNA methyltransferase NSun2 stabilizes p16INK⁴ mRNA by methylating the 3'-untranslated region of p16.
Nature communications 2012;3():712.
2011: Renzhong Li; Liwei Ma; Yu Huang; Zongyu Zhang; Tanjun Tong
Characterization of a novel positive transcription regulatory element that differentially regulates the alpha-2-macroglobulin gene in replicative senescence.
Biogerontology 2011;12(6):517-25.
2011: Na Li; Qian Li; Lixiang Xue; Ganye Zhao; Xiaoxiao Cao; Tanjun Tong
The tumor suppressor p33ING1b upregulates p16INK4a expression and induces cellular senescence.
FEBS letters 2011;585(19):3106-12.
2011: Xiaoxiao Cao; Tianda Chen; Limin Han; Liwei Ma; Lixiang Xue; Tanjun Tong
WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts.
The Journal of biological chemistry 2011;286(38):33447-56.
2011: Jing Niu; Tianda Chen; Limin Han; Pan Wang; Na Li; Tanjun Tong
Transcriptional activation of the senescence regulator Lsh by E2F1.
Mechanisms of ageing and development 2011;132(4):180-6.
2011: Yu Huang; Junfeng Wu; Renzhong Li; Peichang Wang; Limin Han; Zongyu Zhang; Tanjun Tong
B-MYB delays cell aging by repressing p16 (INK4α) transcription.
Cellular and molecular life sciences : CMLS 2011;68(5):893-901.
2010: Limin Han; Rui Zhou; Jing Niu; Michael A McNutt; Pan Wang; Tanjun Tong
SIRT1 is regulated by a PPAR{γ}-SIRT1 negative feedback loop associated with senescence.
Nucleic acids research 2010;38(21):7458-71.
2010: Fang Xu; Xiaotian Zhang; Yutao Lei; Xinwen Liu; Zhenyun Liu; Tanjun Tong; Wengong Wang
Loss of repression of HuR translation by miR-16 may be responsible for the elevation of HuR in human breast carcinoma.
Journal of cellular biochemistry 2010;111(3):727-34.
2010: Na Chang; Jie Yi; Gaier Guo; X Liu; Yongfeng Shang; Tanjun Tong; Qinghua Cui; Ming Zhan; Myriam Gorospe; Wengong Wang
HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.
Molecular and cellular biology 2010;30(15):3875-86.
2010: Jie Yi; Na Chang; Xinwen Liu; Gaier Guo; Lixiang Xue; Tanjun Tong; Myriam Gorospe; Wengong Wang
Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence.
Nucleic acids research 2010;38(5):1547-58.
2010: Peichang Wang; Zongyu Zhang; Ying Sun; Xinwen Liu; Tanjun Tong
The two isomers of HDTIC compounds from Astragali Radix slow down telomere shortening rate via attenuating oxidative stress and increasing DNA repair ability in human fetal lung diploid fibroblast cells.
DNA and cell biology 2010;29(1):33-9.
2009: Rui Zhou; Limin Han; Guodong Li; Tanjun Tong
Senescence delay and repression of p16INK4a by Lsh via recruitment of histone deacetylases in human diploid fibroblasts.
Nucleic acids research 2009;37(15):5183-96.
2008: Liwei Ma; Na Chang; Shuzhen Guo; Qian Li; Zongyu Zhang; Wengong Wang; Tanjun Tong
CSIG inhibits PTEN translation in replicative senescence.
Molecular and cellular biology 2008;28(20):6290-301.
2008: Qini Gan; Jing Huang; Rui Zhou; Jing Niu; Xiaojun Zhu; Jing Wang; Zongyu Zhang; Tanjun Tong
PPAR{gamma} accelerates cellular senescence by inducing p16INK4{alpha} expression in human diploid fibroblasts.
Journal of cell science 2008;121(Pt 13):2235-45.
2008: Jing Huang; Qini Gan; Limin Han; Jian Li; Hai Zhang; Ying Sun; Zongyu Zhang; Tanjun Tong
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts.
PloS one 2008;3(3):e1710.
2007: Junfeng Wu; Lixiang Xue; Mo Weng; Ying Sun; Zongyu Zhang; Wengong Wang; Tanjun Tong
Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.
PloS one 2007;2(1):e164.
2005: Jianming Duan; Jianping Duan; Zongyu Zhang; Tanjun Tong
Irreversible cellular senescence induced by prolonged exposure to H2O2 involves DNA-damage-and-repair genes and telomere shortening.
The international journal of biochemistry & cell biology 2005;37(7):1407-20.
2005: Liang Zhao; Tanjun Tong; Zongyu Zhang
Expression of the Leo1-like domain of replicative senescence down-regulated Leo1-like (RDL) protein promotes senescence of 2BS fibroblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(6):521-32.
2004: Shuzhen Guo; Zongyu Zhang; Tanjun Tong
Cloning and characterization of cellular senescence-associated genes in human fibroblasts by suppression subtractive hybridization.
Experimental cell research 2004;298(2):465-72.
2004: Wenjie Zheng; Heyao Wang; Lixiang Xue; Zongyu Zhang; Tanjun Tong
Regulation of cellular senescence and p16(INK4a) expression by Id1 and E47 proteins in human diploid fibroblast.
The Journal of biological chemistry 2004;279(30):31524-32.
2004: Jianming Duan; Zhong Chen; Pinghu Liu; Zongyu Zhang; Tanjun Tong
Wild-type p16INK4a suppresses cell growth, telomerase activity and DNA repair in human breast cancer MCF-7 cells.
International journal of oncology 2004;24(6):1597-605.
2004: Lixiang Xue; Junfeng Wu; Wenjie Zheng; Peichang Wang; Jun Li; Zongyu Zhang; Tanjun Tong
Sp1 is involved in the transcriptional activation of p16(INK4) by p21(Waf1) in HeLa cells.
FEBS letters 2004;564(1-2):199-204.
2004: Wei-Guo Zhu; Theresa Hileman; Yang Ke; Peichang Wang; Shaoli Lu; Wenrui Duan; Zunyan Dai; Tanjun Tong; Miguel A Villalona-Calero; Christoph Plass; Gregory A Otterson
5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.
The Journal of biological chemistry 2004;279(15):15161-6.
2004: Hong Ma; Renzhong Li; Zongyu Zhang; Tanjun Tong
mRNA level of alpha-2-macroglobulin as an aging biomarker of human fibroblasts in culture.
Experimental gerontology 2004;39(3):415-21.
2003: Peichang Wang; Zongyu Zhang; Xiaofeng Ma; Yu Huang; Xinwen Liu; Pengfei Tu; Tanjun Tong
HDTIC-1 and HDTIC-2, two compounds extracted from Astragali Radix, delay replicative senescence of human diploid fibroblasts.
Mechanisms of ageing and development 2003;124(10-12):1025-34.
2003: Zebin Mao; Shan Song; Yunyan Zhu; Xia Yi; Hua Zhang; Yongfeng Shang; Tanjun Tong
Transcriptional regulation of A33 antigen expression by gut-enriched Krüppel-like factor.
Oncogene 2003;22(28):4434-43.
2003: Shuping Li; Zongyu Zhang; Tanjun Tong
Phosphatidylinositol 3-kinase inhibitor, LY294002, induced senescence-like changes in human diploid fibroblasts.
Chinese medical journal 2003;116(6):901-5.
2003: Xiaowei Zhang; Zhong Chen; Yanling Chen; Tanjun Tong
Delivering antisense telomerase RNA by a hybrid adenovirus/ adeno-associated virus significantly suppresses the malignant phenotype and enhances cell apoptosis of human breast cancer cells.
Oncogene 2003;22(16):2405-16.
2002: Hong Ma; Zongyu Zhang; Tanjun Tong
The effects of epidermal growth factor on gene expression in human fibroblasts.
In vitro cellular & developmental biology. Animal 2002;38(8):481-6.
2001: Wei Wang; Jianmin Wu; ZhiJia Zhang; Tanjun Tong
Characterization of regulatory elements on the promoter region of p16(INK4a) that contribute to overexpression of p16 in senescent fibroblasts.
The Journal of biological chemistry 2001;276(52):48655-61.
2001: Jianming Duan; ZhiJia Zhang; Tanjun Tong
Senescence delay of human diploid fibroblast induced by anti-sense p16INK4a expression.
The Journal of biological chemistry 2001;276(51):48325-31.
1997: Zebin Mao; Zhinan Zhang; Tanjun Tong
Induction of c-fos/c-myc expression by epidermal growth factor decreases with alteration of their gene binding proteins in senescent fibroblasts.
Chinese medical journal 1997;110(10):755-9.