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Yi Tong

Research Profile

Disorders

Leber's Hereditary Optic Atrophy

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Publications

TOP 3
Yu Zhang; Jia Qu; Yi Tong; Yan-chun Ji; Juan-juan Zhang; Ming-lian Zhang; Fu-xin Zhao; Xiang-tian Zhou; Min-xin Guan
[The mitochondrial tRNA(Thr) A15951G mutation may be associated with Leber's hereditary optic neuropathy in two Chinese families].
Jia Qu; Ying Wang; Yi Tong; Xiangtian Zhou; Fuxin Zhao; Li Yang; Shoukang Zhang; Juanjuan Zhang; Constance E West; Min-Xin Guan
Leber's hereditary optic neuropathy affects only female matrilineal relatives in two Chinese families.
Juanjuan Zhang; Xiangtian Zhou; Jian Zhou; Chengwu Li; Fuxin Zhao; Yan Wang; Yanzi Meng; Jiying Wang; Meixia Yuan; Wanshi Cai; Yi Tong; Yan-Hong Sun; Li Yang; Jia Qu; Min-Xin Guan
Mitochondrial ND6 T14502C variant may modulate the phenotypic expression of LHON-associated G11778A mutation in four Chinese families.

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All Publications

2011: Yu Zhang; Jia Qu; Yi Tong; Yan-chun Ji; Juan-juan Zhang; Ming-lian Zhang; Fu-xin Zhao; Xiang-tian Zhou; Min-xin Guan
[The mitochondrial tRNA(Thr) A15951G mutation may be associated with Leber's hereditary optic neuropathy in two Chinese families].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2011;28(5):501-6.
2010: Jia Qu; Ying Wang; Yi Tong; Xiangtian Zhou; Fuxin Zhao; Li Yang; Shoukang Zhang; Juanjuan Zhang; Constance E West; Min-Xin Guan
Leber's hereditary optic neuropathy affects only female matrilineal relatives in two Chinese families.
Investigative ophthalmology & visual science 2010;51(10):4906-12.
2010: Juanjuan Zhang; Xiangtian Zhou; Jian Zhou; Chengwu Li; Fuxin Zhao; Yan Wang; Yanzi Meng; Jiying Wang; Meixia Yuan; Wanshi Cai; Yi Tong; Yan-Hong Sun; Li Yang; Jia Qu; Min-Xin Guan
Mitochondrial ND6 T14502C variant may modulate the phenotypic expression of LHON-associated G11778A mutation in four Chinese families.
Biochemical and biophysical research communications 2010;399(4):647-53.
2010: Xiangtian Zhou; Hongxing Zhang; Fuxin Zhao; Yanchun Ji; Yi Tong; Juanjuan Zhang; Yu Zhang; Li Yang; Yaping Qian; Fan Lu; Jia Qu; Min-Xin Guan
Very high penetrance and occurrence of Leber's hereditary optic neuropathy in a large Han Chinese pedigree carrying the ND4 G11778A mutation.
Molecular genetics and metabolism 2010;100(4):379-84.
2010: Yi Tong; Yan-Hong Sun; Xiangtian Zhou; Fuxin Zhao; Yijian Mao; Qi-ping Wei; Li Yang; Jia Qu; Min-Xin Guan
Very low penetrance of Leber's hereditary optic neuropathy in five Han Chinese families carrying the ND1 G3460A mutation.
Molecular genetics and metabolism 2010;99(4):417-24.
2010: Jia Qu; Xiangtian Zhou; Fuxin Zhao; Xiaoling Liu; Minglian Zhang; Yan-Hong Sun; Min Liang; Meixia Yuan; Qi Liu; Yi Tong; Qi-Ping Wei; Li Yang; Min-Xin Guan
Low penetrance of Leber's hereditary optic neuropathy in ten Han Chinese families carrying the ND6 T11484C mutation.
Biochimica et biophysica acta 2010;1800(3):305-12.
2010: Yan Liu; Shu-Liu Zhuang; Yi Tong; Jia Qu; Xiang-Tian Zhou; Fu-Xin Zhao; Juan-Juan Zhang; Yong-Mei Zhang; Yu Zhang; Min-Xin Guan
[Leber's hereditary optic neuropathy and limbs abnormity claudication may be associated with the mitochondrial ND1 T3866C mutation].
Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 2010;32(2):141-7.
2009: Fuxin Zhao; Minqiang Guan; Xiangtian Zhou; Meixia Yuan; Ming Liang; Qi Liu; Yan Liu; Yongmei Zhang; Li Yang; Yi Tong; Qi-Ping Wei; Yan-Hong Sun; Jia Qu; Min-Xin Guan
Leber's hereditary optic neuropathy is associated with mitochondrial ND6 T14502C mutation.
Biochemical and biophysical research communications 2009;389(3):466-72.
2009: Min Liang; Minqiang Guan; Fuxing Zhao; Xiangtian Zhou; Meixia Yuan; Yi Tong; Li Yang; Qi-Ping Wei; Yan-Hong Sun; Fan Lu; Jia Qu; Min-Xin Guan
Leber's hereditary optic neuropathy is associated with mitochondrial ND1 T3394C mutation.
Biochemical and biophysical research communications 2009;383(3):286-92.
2009: Jia Qu; Xiangtian Zhou; Juanjuan Zhang; Fuxin Zhao; Yan-Hong Sun; Yi Tong; Qi-Ping Wei; Wansi Cai; Li Yang; Constance E West; Min-Xin Guan
Extremely low penetrance of Leber's hereditary optic neuropathy in 8 Han Chinese families carrying the ND4 G11778A mutation.
Ophthalmology 2009;116(3):558-564.e3.
2008: Wanshi Cai; Qun Fu; Xiangtian Zhou; Jia Qu; Yi Tong; Min-Xin Guan
Mitochondrial variants may influence the phenotypic manifestation of Leber's hereditary optic neuropathy-associated ND4 G11778A mutation.
Journal of genetics and genomics = Yi chuan xue bao 2008;35(11):649-55.
2007: Fu-xin Zhao; Xing-tao Zhou; Jia Qu; Qi-ping Wei; Yi Tong; Li Yang; Jian-xin Lv; Min-Xin Guan
[Leber's hereditary optic neuropathy is associated with the mitochondrial G11696A mutation in two Chinese families].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2007;24(5):556-9.
2007: Yi Tong; Yijian Mao; Zhou Xiangtian; Li Yang; Juanjuan Zhang; Wanshi Cai; Fuxing Zhao; Xinjian Wang; Fan Lu; Jia Qu; Min-Xin Guan
The mitochondrial tRNA(Glu) A14693G mutation may influence the phenotypic manifestation of ND1 G3460A mutation in a Chinese family with Leber's hereditary optic neuropathy.
Biochemical and biophysical research communications 2007;357(2):524-30.
2007: Jia Qu; Ronghua Li; Zhou Xiangtian; Yi Tong; Li Yang; Jie Chen; Fuxing Zhao; Chunjie Lu; Yaping Qian; Fan Lu; Min-Xin Guan
Cosegregation of the ND4 G11696A mutation with the LHON-associated ND4 G11778A mutation in a four generation Chinese family.
Mitochondrion 2007;7(1-2):140-6.
2006: Ronghua Li; Jia Qu; Zhou Xiangtian; Yi Tong; Yongwu Hu; Yaping Qian; Fan Lu; Jun Qin Mo; Constance E West; Min-Xin Guan
The mitochondrial tRNA(Thr) A15951G mutation may influence the phenotypic expression of the LHON-associated ND4 G11778A mutation in a Chinese family.
Gene 2006;376(1):79-86.
2006: Zhou Xiangtian; Qiping Wei; Li Yang; Yi Tong; Fuxin Zhao; Chunjie Lu; Yaping Qian; Yanghong Sun; Fan Lu; Jia Qu; Min-Xin Guan
Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families.
Biochemical and biophysical research communications 2006;340(1):69-75.
2006: Jia Qu; Ronghua Li; Zhou Xiangtian; Yi Tong; Fan Lu; Yaping Qian; Yongwu Hu; Jun Qin Mo; Constance E West; Min-Xin Guan
The novel A4435G mutation in the mitochondrial tRNAMet may modulate the phenotypic expression of the LHON-associated ND4 G11778A mutation.
Investigative ophthalmology & visual science 2006;47(2):475-83.
2005: Yaping Qian; Zhou Xiangtian; Yongwu Hu; Yi Tong; Ronghua Li; Fan Lu; Huanming Yang; Jun Qin Mo; Jia Qu; Min-Xin Guan
Clinical evaluation and mitochondrial DNA sequence analysis in three Chinese families with Leber's hereditary optic neuropathy.
Biochemical and biophysical research communications 2005;332(2):614-21.
2005: Jia Qu; Ronghua Li; Yi Tong; Yongwu Hu; Zhou Xiangtian; Yaping Qian; Fan Lu; Min-Xin Guan
Only male matrilineal relatives with Leber's hereditary optic neuropathy in a large Chinese family carrying the mitochondrial DNA G11778A mutation.
Biochemical and biophysical research communications 2005;328(4):1139-45.