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Torsten Tonn

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Birgit Assmus; Stefanie Dimmeler; Walaa Khaled; Jens Klotsche; David M Leistner; Andreas Lutz; Florian H Seeger; Julia Steiner; Torsten Tonn; Dirk H Walter; Ina Ziegler; Andreas M Zeiher
Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: the CELLWAVE randomized clinical trial.
Martin Stern; André Tichelli; Torsten Tonn; P Bader; R Esser; Alois Gratwohl; T Klingebiel; Sandrine Meyer-Monard; Jakob R Passweg; Michael Paulussen; D Schwabe; J Soerensen; Ulrike Koehl
Pre-emptive immunotherapy with purified natural killer cells after haploidentical SCT: a prospective phase II study in two centers.
Kai Gutensohn; J F Kersten; Marcus Odendahl; Torsten Tonn
Validation of cord blood split products prepared by an automated method.

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All Publications

2013: Birgit Assmus; Stefanie Dimmeler; Walaa Khaled; Jens Klotsche; David M Leistner; Andreas Lutz; Florian H Seeger; Julia Steiner; Torsten Tonn; Dirk H Walter; Ina Ziegler; Andreas M Zeiher
Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: the CELLWAVE randomized clinical trial.
JAMA : the journal of the American Medical Association 2013;309(15):1622-31.
2013: Martin Stern; André Tichelli; Torsten Tonn; P Bader; R Esser; Alois Gratwohl; T Klingebiel; Sandrine Meyer-Monard; Jakob R Passweg; Michael Paulussen; D Schwabe; J Soerensen; Ulrike Koehl
Pre-emptive immunotherapy with purified natural killer cells after haploidentical SCT: a prospective phase II study in two centers.
Bone marrow transplantation 2013;48(3):433-8.
2013: Kai Gutensohn; J F Kersten; Marcus Odendahl; Torsten Tonn
Validation of cord blood split products prepared by an automated method.
Transfusion medicine (Oxford, England) 2013;23(1):48-54.
2012: Birgit Assmus; Stefanie Dimmeler; Frank Grünwald; Kazuma Iekushi; Masayoshi Iwasaki; Masamichi Koyanagi; Wolfgang Tilman Kranert; Stefan Liebner; Tino Roexe; Volker Schächinger; Erhard Seifried; Torsten Tonn; Quanfu Xu; Andreas M Zeiher
Acute myocardial infarction activates progenitor cells and increases Wnt signalling in the bone marrow.
European heart journal 2012;33(15):1911-9.
2012: M M Mueller; Michael K Hourfar; E Huber; Erhard Seifried; Walid Sireis; Torsten Tonn; W Weichert; Michael Schmidt
Oxygen measurements in platelet fluids - a new non-invasive method to detect bacterial contaminations in platelets.
Transfusion medicine (Oxford, England) 2012;22(3):211-6.
2012: Ruth Esser; Stephen D Gillies; Nicole Huebener; James S Huston; Stephan Kloess; Ulrike Koehl; Holger N Lode; Tina Müller; Kurt Schönfeld; Diana Seidel; Dörthe Stefes; Torsten Tonn; Christoph Uherek; Christel Aperlo-Iffland; Winfried S Wels
NK cells engineered to express a GD2 -specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin.
Journal of cellular and molecular medicine 2012;16(3):569-81.
2012: Peter Milanov; Patricia Quade-Lyssy; Erhard Seifried; Torsten Tonn; Daniela Abriss; Sonja Alesci; Manuel Grez; Lacramioara Ivanciu; Wolfgang Miesbach; Jörg Schüttrumpf
Engineered factor IX variants bypass FVIII and correct hemophilia A phenotype in mice.
Blood 2012;119(2):602-11.
2012: Stefanie D Roth; Jörg Schüttrumpf; Erhard Seifried; Jeremy C Simpson; Daniela Abriss; Peter Milanov; Rainer Pepperkok; Patricia Quade-Lyssy; Christopher Ungerer; Torsten Tonn
Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A.
PloS one 2012;7(9):e44505.
2011: Katrin Dauber; Daniela Becker; Marcus Odendahl; Erhard Seifried; Halvard Bonig; Torsten Tonn
Enumeration of viable CD34(+) cells by flow cytometry in blood, bone marrow and cord blood: results of a study of the novel BD™ stem cell enumeration kit.
Cytotherapy 2011;13(4):449-58.
2011: Dirk H Walter; Hans Krankenberg; Jörn O Balzer; Christoph Kalka; Iris Baumgartner; Michael Schlüter; Torsten Tonn; Florian Seeger; Stefanie Dimmeler; Edelgard Lindhoff-Last; Andreas M Zeiher
Intraarterial administration of bone marrow mononuclear cells in patients with critical limb ischemia: a randomized-start, placebo-controlled pilot trial (PROVASA).
Circulation. Cardiovascular interventions 2011;4(1):26-37.
2011: Jörg Schüttrumpf; Peter Milanov; Daniela Abriss; Stefanie Roth; Torsten Tonn; Erhard Seifried
Transgene loss and changes in the promoter methylation status as determinants for expression duration in nonviral gene transfer for factor IX.
Human gene therapy 2011;22(1):101-6.
2010: Birgit Assmus; Torsten Tonn; Florian H Seeger; Chang-Hwan Yoon; David Leistner; Jens Klotsche; Volker Schächinger; Erhard Seifried; Andreas M Zeiher; Stefanie Dimmeler
Red blood cell contamination of the final cell product impairs the efficacy of autologous bone marrow mononuclear cell therapy.
Journal of the American College of Cardiology 2010;55(13):1385-94.
2010: Sabine Huenecke; Stefanie-Yvonne Zimmermann; Stephan Kloess; Ruth Esser; Andrea Brinkmann; Lars Tramsen; Melanie Koenig; Stephanie Erben; Christian Seidl; Torsten Tonn; Angelika Eggert; Alexander Schramm; Peter Bader; Thomas Klingebiel; Thomas Lehrnbecher; Jakob Robert Passweg; Jan Soerensen; Dirk Schwabe; Ulrike Koehl
IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusion.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(2):200-10.
2010: Birgit Assmus; Andreas Rolf; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Harald Tillmanns; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Torsten Tonn; Stefanie Dimmeler; Thorsten Dill; Andreas M Zeiher; Volker Schächinger
Clinical outcome 2 years after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarction.
Circulation. Heart failure 2010;3(1):89-96.
2009: Michael Schmidt; Hans-Peter Spengler; Bernd Lambrecht; Michael K Hourfar; Erhard Seifried; Torsten Tonn
A new one-platform flow cytometric method for residual cell counting in platelet concentrates.
Transfusion 2009;49(12):2604-11.
2009: Stefan Heinz; Jörg Schüttrumpf; Jeremy C Simpson; Rainer Pepperkok; Gerry A Nicolaes; Daniela Abriss; Peter Milanov; Stefanie Roth; Erhard Seifried; Torsten Tonn
Factor VIII-eGFP fusion proteins with preserved functional activity for the analysis of the early secretory pathway of factor VIII.
Thrombosis and haemostasis 2009;102(5):925-35.
2009: Volker Schächinger; Birgit Assmus; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial infarction (REPAIR-AMI) trial.
European journal of heart failure 2009;11(10):973-9.
2009: Ulrich Fischer-Rasokat; Birgit Assmus; Florian H Seeger; Jörg Honold; David Leistner; Stephan Fichtlscherer; Volker Schächinger; Torsten Tonn; Hans Martin; Stefanie Dimmeler; Andreas M Zeiher
A pilot trial to assess potential effects of selective intracoronary bone marrow-derived progenitor cell infusion in patients with nonischemic dilated cardiomyopathy: final 1-year results of the transplantation of progenitor cells and functional regeneration enhancement pilot trial in patients with nonischemic dilated cardiomyopathy.
Circulation. Heart failure 2009;2(5):417-23.
2009: G Weber; J Karbach; Selim Kuçi; Hermann Kreyenberg; A Willasch; Ewa Koscielniak; Torsten Tonn; Thomas Klingebiel; Winfried S Wels; E Jäger; Peter Bader
WT1 peptide-specific T cells generated from peripheral blood of healthy donors: possible implications for adoptive immunotherapy after allogeneic stem cell transplantation.
Leukemia 2009;23(9):1634-42.
2009: Elizabeth Ramos Lopez; F Scholten; F Aminkeng; C Wild; H Kalhes; Christian Seidl; Torsten Tonn; Bart J R Van der Auwera; Klaus Badenhoop
Association of KIR2DL2 polymorphism rs2756923 with type 1 diabetes and preliminary evidence for lack of inhibition through HLA-C1 ligand binding.
Tissue antigens 2009;73(6):599-603.
2009: L Tramsen; Ulrike Koehl; Torsten Tonn; Jean-Paul Latgé; Friedhelm R Schuster; A Borkhardt; L Uharek; R Quaritsch; Olaf Beck; Erhard Seifried; Thomas Klingebiel; Thomas Lehrnbecher
Clinical-scale generation of human anti-Aspergillus T cells for adoptive immunotherapy.
Bone marrow transplantation 2009;43(1):13-9.
2008: J Schüttrumpf; P Milanov; S Roth; Erhard Seifried; Torsten Tonn
[Non-viral gene transfer results in therapeutic factor IX levels in haemophilia B mice].
Hämostaseologie 2008;28 Suppl 1():S92-5.
2007: Gesine Bug; Konstantinos Anargyrou; Torsten Tonn; Heike Bialleck; Erhard Seifried; Dieter Hoelzer; Oliver G Ottmann
Impact of leukapheresis on early death rate in adult acute myeloid leukemia presenting with hyperleukocytosis.
Transfusion 2007;47(10):1843-50.
2007: Sandra Erbs; Axel Linke; Volker Schächinger; Birgit Assmus; Holger Thiele; Klaus-Werner Diederich; Christina Hoffmann; Stefanie Dimmeler; Torsten Tonn; Rainer Hambrecht; Andreas M Zeiher; Gerhard Schuler
Restoration of microvascular function in the infarct-related artery by intracoronary transplantation of bone marrow progenitor cells in patients with acute myocardial infarction: the Doppler Substudy of the Reinfusion of Enriched Progenitor Cells and Infarct Remodeling in Acute Myocardial Infarction (REPAIR-AMI) trial.
Circulation 2007;116(4):366-74.
2007: Birgit Assmus; Ulrich Fischer-Rasokat; Jörg Honold; Florian H Seeger; Stephan Fichtlscherer; Torsten Tonn; Erhard Seifried; Volker Schächinger; Stefanie Dimmeler; Andreas M Zeiher
Transcoronary transplantation of functionally competent BMCs is associated with a decrease in natriuretic peptide serum levels and improved survival of patients with chronic postinfarction heart failure: results of the TOPCARE-CHD Registry.
Circulation research 2007;100(8):1234-41.
2007: Florian H Seeger; Torsten Tonn; Nicola Krzossok; Andreas M Zeiher; Stefanie Dimmeler
Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction.
European heart journal 2007;28(6):766-72.
2007: V Picanço; S Heinz; D Bott; M Behrmann; Dimas Tadeu Covas; Erhard Seifried; Torsten Tonn
Recombinant expression of coagulation factor VIII in hepatic and non-hepatic cell lines stably transduced with third generation lentiviral vectors comprising the minimal factor VIII promoter.
Cytotherapy 2007;9(8):785-94.
2006: Volker Schächinger; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Hans Hölschermann; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Nikos Werner; Jürgen Haase; Joerg Neuzner; Alfried Germing; Bernd Mark; Birgit Assmus; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial.
European heart journal 2006;27(23):2775-83.
2006: Birgit Assmus; Jörg Honold; Volker Schächinger; Martina B Britten; Ulrich Fischer-Rasokat; Ralf Lehmann; Claudius Teupe; Katrin Pistorius; Hans Martin; Nasreddin D Abolmaali; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Transcoronary transplantation of progenitor cells after myocardial infarction.
The New England journal of medicine 2006;355(12):1222-32.
2006: Volker Schächinger; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Hans Hölschermann; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Birgit Assmus; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.
The New England journal of medicine 2006;355(12):1210-21.
2006: Michael Schmidt; Michael K Hourfar; Sven-Boris Nicol; Alexandra Wahl; Julia Heck; Christina Weis; Torsten Tonn; Hans-Peter Spengler; Thomas Montag; Erhard Seifried; W Kurt Roth
A comparison of three rapid bacterial detection methods under simulated real-life conditions.
Transfusion 2006;46(8):1367-73.
2006: Volker Schächinger; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Bone-marrow-derived progenitor cell therapy in need of proof of concept: design of the REPAIR-AMI trial.
Nature clinical practice. Cardiovascular medicine 2006;3 Suppl 1():S23-8.
2005: Ulrike Koehl; Ruth Esser; Stefanie-Yvonne Zimmermann; Torsten Tonn; Rouslan Kotchetkov; T Bartling; Jan Sörensen; Hans-Peter Grüttner; Peter Bader; Erhard Seifried; Hans Martin; P Lang; Jakob R Passweg; Thomas Klingebiel; Dirk Schwabe
Ex vivo expansion of highly purified NK cells for immunotherapy after haploidentical stem cell transplantation in children.
Klinische Pädiatrie 2005;217(6):345-50.
2005: Annette Romanski; Gesine Bug; Sven Becker; Manuela Kampfmann; Erhard Seifried; Dieter Hoelzer; Oliver G Ottmann; Torsten Tonn
Mechanisms of resistance to natural killer cell-mediated cytotoxicity in acute lymphoblastic leukemia.
Experimental hematology 2005;33(3):344-52.
2004: Ulrike Koehl; Jan Sörensen; Ruth Esser; Stefanie-Yvonne Zimmermann; Hans-Peter Grüttner; Torsten Tonn; Christian Seidl; Erhard Seifried; Thomas Klingebiel; Dirk Schwabe
IL-2 activated NK cell immunotherapy of three children after haploidentical stem cell transplantation.
Blood cells, molecules & diseases 2004;33(3):261-6.
2003: Sven Becker; Torsten Tonn; Tobias Füssel; Markus Uhrberg; Manuela Bogdanow; Erhard Seifried; Christian Seidl
Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.
Human immunology 2003;64(2):183-93.
2001: Torsten Tonn; Sven Becker; Ruth Esser; Dirk Schwabe; Erhard Seifried
Cellular immunotherapy of malignancies using the clonal natural killer cell line NK-92.
Journal of hematotherapy & stem cell research 2001;10(4):535-44.
1997: Torsten Tonn; Dagmar Westrup; Christian Seidl; Carl M Kirchmaier; Erhard Seifried
Sensitive determination of the RhD genotype in mixed samples using fluorescence-based polymerase chain reaction.
Vox sanguinis 1997;72(3):177-81.