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Giovanni Tonon

Research Profile

Disorders

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TOP 3
klaus podar; Martin Sattler; Yu-Tzu Tai; Giovanni Tonon; Sonia Vallet; Alexander Zimmerhackl; Dharminder Chauhan; Mariateresa Fulciniti; Ursula Hainz; Niels Halama; Dirk Jäger; Dian L Olson; Kenneth C Anderson
The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications.
Yu-Tzu Tai; Ender Soydan; Weihua Song; Mariateresa Fulciniti; Kihyun Kim; Fangxin Hong; Xian-Feng Li; Peter C Burger; Matthew J Rumizen; Sabikun Nahar; klaus podar; Teru Hideshima; Nikhil C Munshi; Giovanni Tonon; Ruben D Carrasco; Daniel E H Afar; Kenneth C Anderson
CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells.
Giovanni Tonon
From oncogene to network addiction: the new frontier of cancer genomics and therapeutics.

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All Publications

2011: klaus podar; Martin Sattler; Yu-Tzu Tai; Giovanni Tonon; Sonia Vallet; Alexander Zimmerhackl; Dharminder Chauhan; Mariateresa Fulciniti; Ursula Hainz; Niels Halama; Dirk Jäger; Dian L Olson; Kenneth C Anderson
The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications.
British journal of haematology 2011;155(4):438-48.
2009: Yu-Tzu Tai; Ender Soydan; Weihua Song; Mariateresa Fulciniti; Kihyun Kim; Fangxin Hong; Xian-Feng Li; Peter C Burger; Matthew J Rumizen; Sabikun Nahar; klaus podar; Teru Hideshima; Nikhil C Munshi; Giovanni Tonon; Ruben D Carrasco; Daniel E H Afar; Kenneth C Anderson
CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells.
Blood 2009;113(18):4309-18.
2008: Giovanni Tonon
From oncogene to network addiction: the new frontier of cancer genomics and therapeutics.
Future oncology (London, England) 2008;4(4):569-77.
2008: Giovanni Tonon; Kenneth C Anderson
Moving toward individualized cancer therapies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4682-4.
2007: Giovanni Tonon
Molecular pathogenesis of multiple myeloma.
Hematology/oncology clinics of North America 2007;21(6):985-1006, vii.
2007: Eric S Martin; Giovanni Tonon; Raktim Sinha; Yonghong Xiao; Bin Feng; Alec C Kimmelman; Alexei Protopopov; Elena Ivanova; Cameron Brennan; Kate Montgomery; Raju Kucherlapati; Gerald Bailey; Mark Redston; Lynda Chin; Ronald A DePinho
Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types.
Cancer research 2007;67(22):10736-43.
2007: Teru Hideshima; Constantine S Mitsiades; Giovanni Tonon; Paul G Richardson; Kenneth C Anderson
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets.
Nature reviews. Cancer 2007;7(8):585-98.
2007: Daniel R Carrasco; Kumar Sukhdeo; Marina Protopopova; Raktim Sinha; Miriam Enos; Daniel E Carrasco; Mei Zheng; Mala Mani; Joel Henderson; Geraldine S Pinkus; Nikhil C Munshi; James W Horner; Elena V Ivanova; Alexei Protopopov; Kenneth C Anderson; Giovanni Tonon; Ronald A DePinho
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis.
Cancer cell 2007;11(4):349-60.
2007: klaus podar; Marc S Raab; Giovanni Tonon; Martin Sattler; Daniela Barilà; Jing Zhang; Yu-Tzu Tai; Hiroshi Yasui; Noopur Raje; Ronald A DePinho; Teru Hideshima; Dharminder Chauhan; Kenneth C Anderson
Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma.
Cancer research 2007;67(4):1680-8.
2006: klaus podar; Giovanni Tonon; Martin Sattler; Yu-Tzu Tai; Steven Legouill; Hiroshi Yasui; Kenji Ishitsuka; Shaji Kumar; Rakesh Kumar; Lini Pandite; Teru Hideshima; Dharminder Chauhan; Kenneth C Anderson
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(51):19478-83.
2006: Daniel R Carrasco; Giovanni Tonon; Yongsheng Huang; Yunyu Zhang; Raktim Sinha; Bin Feng; James P Stewart; Fenghuang Zhan; Deepak Khatry; Marina Protopopova; Alexei Protopopov; Kumar Sukhdeo; Ichiro Hanamura; Owen Stephens; Bart Barlogie; Kenneth C Anderson; Lynda Chin; John D Shaughnessy; Cameron Brennan; Ronald A DePinho
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients.
Cancer cell 2006;9(4):313-25.
2006: Hongbin Ji; A McGarry Houghton; T J Mariani; S Perera; Carla F. Kim; Robert F Padera; Giovanni Tonon; Kate McNamara; L A Marconcini; Aram F Hezel; N El-Bardeesy; Roderick T Bronson; D Sugarbaker; richard s maser; Steven D Shapiro; Kwok-Kin Wong
K-ras activation generates an inflammatory response in lung tumors.
Oncogene 2006;25(14):2105-12.
2005: Giovanni Tonon; Kwok-Kin Wong; Gautam Maulik; Cameron Brennan; Bin Feng; Yunyu Zhang; Deepak Khatry; Alexei Protopopov; Mingjian James You; Andrew J Aguirre; Eric S Martin; Zhaohui Yang; Hongbin Ji; Lynda Chin; Ronald A DePinho
High-resolution genomic profiles of human lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(27):9625-30.
2005: Giovanni Tonon; Cameron Brennan; Alexei Protopopov; Gautam Maulik; Bin Feng; Yunyu Zhang; Deepak Khatry; Mingjian James You; Andrew J Aguirre; Eric S Martin; Z Yang; Hongbin Ji; Lynda Chin; Kwok-Kin Wong; Ronald A DePinho
Common and contrasting genomic profiles among the major human lung cancer subtypes.
Cold Spring Harbor symposia on quantitative biology 2005;70():11-24.