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Vladimir Torchilin

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Abraham H Abouzeid; Vladimir P Torchilin
The role of cell cycle in the efficiency and activity of cancer nanomedicines.
Vladimir P Torchilin
Interview with Vladimir P Torchilin: liposomal carriers for drug delivery.
Dmitry Nedosekin; Mustafa Sarimollaoglu; Rupa Sawant; Vladimir P Torchilin; Vladislav V Verkhusha; Alexandru Biris; Markus H Frank; Ekaterina I Galanzha; Jie Ma; Vladimir P Zharov
Synergy of photoacoustic and fluorescence flow cytometry of circulating cells with negative and positive contrasts.

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All Publications

2013: Abraham H Abouzeid; Vladimir P Torchilin
The role of cell cycle in the efficiency and activity of cancer nanomedicines.
Expert opinion on drug delivery 2013;10(6):775-86.
2013: Vladimir P Torchilin
Interview with Vladimir P Torchilin: liposomal carriers for drug delivery.
Therapeutic delivery 2013;4(5):537-8.
2013: Dmitry Nedosekin; Mustafa Sarimollaoglu; Rupa Sawant; Vladimir P Torchilin; Vladislav V Verkhusha; Alexandru Biris; Markus H Frank; Ekaterina I Galanzha; Jie Ma; Vladimir P Zharov
Synergy of photoacoustic and fluorescence flow cytometry of circulating cells with negative and positive contrasts.
Journal of biophotonics 2013;6(5):425-34.
2013: Mine Silindir; A Lale Doğan; Suna Erdoğan; Murat Tuncel; A Yekta Ozer; Ömer Uğur; Vladimir P Torchilin
Nanosized multifunctional liposomes for tumor diagnosis and molecular imaging by SPECT/CT.
Journal of liposome research 2013;23(1):20-7.
2013: Sara Movassaghian; Farshad H Shirazi; Alexander Koshkaryev; Hamid R Moghimi; Malav S Trivedi; Vladimir P Torchilin
Efficient down-regulation of PKC-α gene expression in A549 lung cancer cells mediated by antisense oligodeoxynucleotides in dendrosomes.
International journal of pharmaceutics 2013;441(1-2):82-91.
2013: Federico Perche; Vladimir P Torchilin
Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting.
Journal of drug delivery 2013;2013():705265.
2013: Tiziana Musacchio; Vladimir P Torchilin
siRNA delivery: from basics to therapeutic applications.
Frontiers in bioscience : a journal and virtual library 2013;18():58-79.
2013: Swati Biswas; Pranali P Deshpande; Namita S Dodwadkar; Gemma Navarro; Vladimir P Torchilin
Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery.
Biomaterials 2013;34(4):1289-301.
2013: Hong Wu; Lin Zhu; Vladimir P Torchilin
pH-sensitive poly(histidine)-PEG/DSPE-PEG co-polymer micelles for cytosolic drug delivery.
Biomaterials 2013;34(4):1213-22.
2013: Lin Zhu; Vladimir P Torchilin
Stimulus-responsive nanopreparations for tumor targeting.
Integrative biology : quantitative biosciences from nano to macro 2013;5(1):96-107.
2012: Federico Perche; Niravkumar R Patel; Vladimir P Torchilin
Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG-PE micelles in ovarian cancer cell spheroid model.
Journal of controlled release : official journal of the Controlled Release Society 2012;164(1):95-102.
2012: Can Sarisozen; A Atilla Hincal; Tatyana Levchenko; Imran Vural; Vladimir P Torchilin
Long-circulating PEG-PE micelles co-loaded with paclitaxel and elacridar (GG918) overcome multidrug resistance.
Drug delivery 2012;19(8):363-70.
2012: Yuen-Sum Lau; Robert Blouin; Diana Brixner; Lynn Crismon; Stephen Cutler; Rodney Ho; William Jusko; Milap Nahata; Christine Sorkness; Vladimir P Torchilin; Susanna Wu-Pong
Report of the 2011-2012 AACP Special Advisory Committee on Research and Graduate Education.
American journal of pharmaceutical education 2012;76(8):S14.
2012: Rupa R Sawant; Aditi M Jhaveri; Vladimir P Torchilin
Immunomicelles for advancing personalized therapy.
Advanced drug delivery reviews 2012;64(13):1436-46.
2012: Federico Perche; Vladimir P Torchilin
Cancer cell spheroids as a model to evaluate chemotherapy protocols.
Cancer biology & therapy 2012;13(12):1205-13.
2012: B Miao; B Schaffhausen; Igor Skidan; Vladimir P Torchilin; J Yang; Z You; J Yuan; M Famulok; X Fu; Alexei Degterev
Inhibition of cell migration by PITENINs: the role of ARF6.
Oncogene 2012;31(39):4317-32.
2012: Erez Koren; Vladimir P Torchilin
Cell-penetrating peptides: breaking through to the other side.
Trends in molecular medicine 2012;18(7):385-93.
2012: Erez Koren; Anjali Apte; Ankur Jani; Vladimir P Torchilin
Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity.
Journal of controlled release : official journal of the Controlled Release Society 2012;160(2):264-73.
2012: Changhong Xing; Shuzhen Guo; Tatyana Levchenko; Monique F Stins; Vladimir P Torchilin; Eng H Lo
Delivering minocycline into brain endothelial cells with liposome-based technology.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(6):983-8.
2012: Swati Biswas; Namita S Dodwadkar; Aleksandr Piroyan; Vladimir P Torchilin
Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria.
Biomaterials 2012;33(18):4773-82.
2012: Rupa R Sawant; Vladimir P Torchilin
Challenges in development of targeted liposomal therapeutics.
The AAPS journal 2012;14(2):303-15.
2012: Anders Etzerodt; Jonas Graversen; Maciej Bogdan Maniecki; Holger Jon Møller; Vladimir P Torchilin; Søren Kragh Moestrup
Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163.
Journal of controlled release : official journal of the Controlled Release Society 2012;160(1):72-80.
2012: Swati Biswas; Pranali P Deshpande; Namita S Dodwadkar; Vladimir P Torchilin
Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo.
Journal of controlled release : official journal of the Controlled Release Society 2012;159(3):393-402.
2012: Can Sarisozen; A Atilla Hincal; Tatyana Levchenko; Imran Vural; Vladimir P Torchilin
PEG-PE-based micelles co-loaded with paclitaxel and cyclosporine A or loaded with paclitaxel and targeted by anticancer antibody overcome drug resistance in cancer cells.
Drug delivery 2012;19(4):169-76.
2012: Rupa R Sawant; Shravan Kumar Sriraman; Swati Biswas; Riddhi A Dalvi; Gemma Navarro; Vladimir P Torchilin
Polyethyleneimine-lipid conjugate-based pH-sensitive micellar carrier for gene delivery.
Biomaterials 2012;33(15):3942-51.
2012: Tao Wang; Jaydev R Upponi; Vladimir P Torchilin
Design of multifunctional non-viral gene vectors to overcome physiological barriers: dilemmas and strategies.
International journal of pharmaceutics 2012;427(1):3-20.
2012: Lin Zhu; Pooja Kate; Vladimir P Torchilin
Matrix metalloprotease 2-responsive multifunctional liposomal nanocarrier for enhanced tumor targeting.
ACS nano 2012;6(4):3491-8.
2012: Kinh-Luan Dao; J Adam Hendricks; Victoria Ronga; Rupa R Sawant; Vladimir P Torchilin; Robert N Hanson
Design, synthesis, and initial biological evaluation of a steroidal anti-estrogen-doxorubicin bioconjugate for targeting estrogen receptor-positive breast cancer cells.
Bioconjugate chemistry 2012;23(4):785-95.
2012: T Chernenko; Max Diem; Milos Miljkovic; L Quintero; R R Sawant; Vladimir P Torchilin
Raman microscopy for noninvasive imaging of pharmaceutical nanocarriers: intracellular distribution of cationic liposomes of different composition.
Molecular pharmaceutics 2012;9(4):930-6.
2012: Tatiana S Levchenko; William C Hartner; Vladimir P Torchilin
Liposomes for cardiovascular targeting.
Therapeutic delivery 2012;3(4):501-14.
2012: Rupa R Sawant; Onkar S Vaze; Tao Wang; Gerard G M D'Souza; Keyur Gada; Ban-An Khaw; Karen Rockwell; Vladimir P Torchilin
Palmitoyl ascorbate liposomes and free ascorbic acid: comparison of anticancer therapeutic effects upon parenteral administration.
Pharmaceutical research 2012;29(2):375-83.
2012: Tatiana S Levchenko; William C Hartner; Vladimir P Torchilin
Liposomes in diagnosis and treatment of cardiovascular disorders.
Methodist DeBakey cardiovascular journal 2012;8(1):36-41.
2012: Alexander Koshkaryev; Aleksandr Piroyan; Vladimir P Torchilin
Increased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes.
Cancer biology & therapy 2012;13(1):50-60.
2011: Sara Movassaghian; Farshad H Shirazi; Hamid R Moghimi; Vladimir P Torchilin
Dendrosome-dendriplex inside liposomes: as a gene delivery system.
Journal of drug targeting 2011;19(10):925-32.
2011: Igor Meerovich; Ritesh Thekkedath; Alexander Koshkaryev; Vladimir P Torchilin
Screening and optimization of ligand conjugates for lysosomal targeting.
Bioconjugate chemistry 2011;22(11):2271-82.
2011: Swati Biswas; Namita S Dodwadkar; Rupa R Sawant; Vladimir P Torchilin
Development of the novel PEG-PE-based polymer for the reversible attachment of specific ligands to liposomes: synthesis and in vitro characterization.
Bioconjugate chemistry 2011;22(10):2005-13.
2011: Tao Wang; Gerard G M D'Souza; Nikita Kulkarni; Valery A Petrenko; Vladimir P Torchilin
On the mechanism of targeting of phage fusion protein-modified nanocarriers: only the binding peptide sequence matters.
Molecular pharmaceutics 2011;8(5):1720-8.
2011: Niravkumar R Patel; Alok Rathi; Dmitriy Mongayt; Vladimir P Torchilin
Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes.
International journal of pharmaceutics 2011;416(1):296-9.
2011: Alexander Koshkaryev; Igor Meerovich; Cinzia Pagano; Ritesh Thekkedath; Vladimir P Torchilin
Targeting of lysosomes by liposomes modified with octadecyl-rhodamine B.
Journal of drug targeting 2011;19(8):606-14.
2011: Tao Wang; Deepa Bedi; Gerard G M D'Souza; Nikita Kulkarni; Brigitte Papahadjopoulos-Sternberg; Valery A Petrenko; Vladimir P Torchilin
In vitro optimization of liposomal nanocarriers prepared from breast tumor cell specific phage fusion protein.
Journal of drug targeting 2011;19(8):597-605.
2011: Erez Koren; Vladimir P Torchilin
Drug carriers for vascular drug delivery.
IUBMB life 2011;63(8):586-95.
2011: Swati Biswas; Namita S Dodwadkar; Alexander Koshkaryev; Rupa R Sawant; Vladimir P Torchilin
Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting.
Journal of drug targeting 2011;19(7):552-61.
2011: Erez Koren; Rupa R Sawant; Anjali Apte; Jacob Grunwald; Vladimir P Torchilin
Cell-penetrating TAT peptide in drug delivery systems: proteolytic stability requirements.
Drug delivery 2011;18(5):377-84.
2011: Salome Siavoshi; Cihan Yilmaz; Sivasubramanian Somu; Tiziana Musacchio; Jaydev R Upponi; Vladimir P Torchilin; Ahmed Busnaina
Size-selective template-assisted electrophoretic assembly of nanoparticles for biosensing applications.
Langmuir : the ACS journal of surfaces and colloids 2011;27(11):7301-6.
2011: Deepa Bedi; Tiziana Musacchio; Olusegun Fagbohun; James W Gillespie; Patricia DeInnocentes; R Curtis Bird; Lonnie Bookbinder; Vladimir P Torchilin; Valery A Petrenko
Delivery of siRNA into breast cancer cells via phage fusion protein-targeted liposomes.
Nanomedicine : nanotechnology, biology, and medicine 2011;7(3):315-23.
2011: P Pattekari; Z Zheng; X Zhang; T Levchenko; Vladimir P Torchilin; Yuri M Lvov
Top-down and bottom-up approaches in production of aqueous nanocolloids of low solubility drug paclitaxel.
Physical chemistry chemical physics : PCCP 2011;13(19):9014-9.
2011: Rita E Serda; Elvin Blanco; Aaron Mack; Susan J Stafford; Sarah Amra; Qingpo Li; Anne van de Ven; Takemi Tanaka; Vladimir P Torchilin; John E Wiktorowicz; Mauro Ferrari
Proteomic analysis of serum opsonins impacting biodistribution and cellular association of porous silicon microparticles.
Molecular imaging 2011;10(1):43-55.
2011: Rupa R Sawant; Onkar Vaze; Gerard G M D'Souza; Karen Rockwell; Vladimir P Torchilin
Palmitoyl ascorbate-loaded polymeric micelles: cancer cell targeting and cytotoxicity.
Pharmaceutical research 2011;28(2):301-8.
2011: Rebecca S Tirabassi; Christopher I Ace; Tatyana Levchenko; Vladimir P Torchilin; Liisa K Selin; Siwei Nie; Dennis L Guberski; Kejian Yang
A mucosal vaccination approach for herpes simplex virus type 2.
Vaccine 2011;29(5):1090-8.
2011: Rupa R Sawant; Vladimir P Torchilin
Design and synthesis of novel functional lipid-based bioconjugates for drug delivery and other applications.
Methods in molecular biology (Clifton, N.J.) 2011;751():357-78.
2011: Tiziana Musacchio; Vladimir P Torchilin
Recent developments in lipid-based pharmaceutical nanocarriers.
Frontiers in bioscience : a journal and virtual library 2011;16():1388-412.
2010: Wei Yang; Muneeb Ahmed; Mostafa Elian; El-Shymma A Hady; Tatyana S Levchenko; Rupa R Sawant; Sabina Signoretti; Michael Collins; Vladimir P Torchilin; S Nahum Goldberg
Do liposomal apoptotic enhancers increase tumor coagulation and end-point survival in percutaneous radiofrequency ablation of tumors in a rat tumor model?
Radiology 2010;257(3):685-96.
2010: Rupa R Sawant; Vladimir P Torchilin
Multifunctionality of lipid-core micelles for drug delivery and tumour targeting.
Molecular membrane biology 2010;27(7):232-46.
2010: Niravkumar R Patel; Sophia Hatziantoniou; Aristidis Georgopoulos; Costas Demetzos; Vladimir P Torchilin; Volkmar Weissig; Gerard G M D'Souza
Mitochondria-targeted liposomes improve the apoptotic and cytotoxic action of sclareol.
Journal of liposome research 2010;20(3):244-9.
2010: Tiziana Musacchio; Onkar Vaze; Gerard G M D'Souza; Vladimir P Torchilin
Effective stabilization and delivery of siRNA: reversible siRNA-phospholipid conjugate in nanosized mixed polymeric micelles.
Bioconjugate chemistry 2010;21(8):1530-6.
2010: Tao Wang; Valery A Petrenko; Vladimir P Torchilin
Paclitaxel-loaded polymeric micelles modified with MCF-7 cell-specific phage protein: enhanced binding to target cancer cells and increased cytotoxicity.
Molecular pharmaceutics 2010;7(4):1007-14.
2010: Tao Wang; Shenghong Yang; Valery A Petrenko; Vladimir P Torchilin
Cytoplasmic delivery of liposomes into MCF-7 breast cancer cells mediated by cell-specific phage fusion coat protein.
Molecular pharmaceutics 2010;7(4):1149-58.
2010: Vladimir P Torchilin
Antinuclear antibodies with nucleosome-restricted specificity for targeted delivery of chemotherapeutic agents.
Therapeutic delivery 2010;1(2):257-72.
2010: Rupa R Sawant; Onkar S Vaze; Karen Rockwell; Vladimir P Torchilin
Palmitoyl ascorbate-modified liposomes as nanoparticle platform for ascorbate-mediated cytotoxicity and paclitaxel co-delivery.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2010;75(3):321-6.
2010: Prashanth K Jayanna; Deepa Bedi; James W Gillespie; Patricia DeInnocentes; Tao Wang; Vladimir P Torchilin; Richard C Bird; Valery A Petrenko
Landscape phage fusion protein-mediated targeting of nanomedicines enhances their prostate tumor cell association and cytotoxic efficiency.
Nanomedicine : nanotechnology, biology, and medicine 2010;6(4):538-46.
2010: Tao Wang; Gerard G M D'Souza; Deepa Bedi; Olusegun Fagbohun; L Prasanna Potturi; Brigitte Papahadjopoulos-Sternberg; Valery A Petrenko; Vladimir P Torchilin
Enhanced binding and killing of target tumor cells by drug-loaded liposomes modified with tumor-specific phage fusion coat protein.
Nanomedicine (London, England) 2010;5(4):563-74.
2010: Rupa R Sawant; Vladimir P Torchilin
Polymeric micelles: polyethylene glycol-phosphatidylethanolamine (PEG-PE)-based micelles as an example.
Methods in molecular biology (Clifton, N.J.) 2010;624():131-49.
2010: Vladimir P Torchilin
Passive and active drug targeting: drug delivery to tumors as an example.
Handbook of experimental pharmacology 2010;(197):3-53.
2010: Tatiana S Levchenko; William C Hartner; Daya D Verma; Eugene A Bernstein; Vladimir P Torchilin
ATP-loaded liposomes for targeted treatment in models of myocardial ischemia.
Methods in molecular biology (Clifton, N.J.) 2010;605():361-75.
2010: Suna Erdogan; Vladimir P Torchilin
Gadolinium-loaded polychelating polymer-containing tumor-targeted liposomes.
Methods in molecular biology (Clifton, N.J.) 2010;605():321-34.
2010: Amit A Kale; Vladimir P Torchilin
Environment-responsive multifunctional liposomes.
Methods in molecular biology (Clifton, N.J.) 2010;605():213-42.
2010: Tamer A Elbayoumi; Vladimir P Torchilin
Current trends in liposome research.
Methods in molecular biology (Clifton, N.J.) 2010;605():1-27.
2009: Stefano Salmaso; Juan S Pappalardo; Rupa R Sawant; Tiziana Musacchio; Karen Rockwell; Paolo Caliceti; Vladimir P Torchilin
Targeting glioma cells in vitro with ascorbate-conjugated pharmaceutical nanocarriers.
Bioconjugate chemistry 2009;20(12):2348-55.
2009: T Musacchio; M Toniutti; Roger A Kautz; Vladimir P Torchilin
1H NMR detection of mobile lipids as a marker for apoptosis: the case of anticancer drug-loaded liposomes and polymeric micelles.
Molecular pharmaceutics 2009;6(6):1876-82.
2009: William C Hartner; Daya D Verma; Tatyana S Levchenko; Eugene A Bernstein; Vladimir P Torchilin
ATP-loaded liposomes for treatment of myocardial ischemia.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2009;1(5):530-9.
2009: Jacob Grunwald; Tomas Rejtar; Rishikesh M Sawant; Zhouxi Wang; Vladimir P Torchilin
TAT peptide and its conjugates: proteolytic stability.
Bioconjugate chemistry 2009;20(8):1531-7.
2009: Rupa R Sawant; Vladimir P Torchilin
Enhanced cytotoxicity of TATp-bearing paclitaxel-loaded micelles in vitro and in vivo.
International journal of pharmaceutics 2009;374(1-2):114-8.
2009: Aristarchos Papagiannaros; Tatyana Levchenko; William Hartner; Dmitriy A Mongayt; Vladimir P Torchilin
Quantum dots encapsulated in phospholipid micelles for imaging and quantification of tumors in the near-infrared region.
Nanomedicine : nanotechnology, biology, and medicine 2009;5(2):216-24.
2009: Young Tag Ko; Claudio Falcao; Vladimir P Torchilin
Cationic liposomes loaded with proapoptotic peptide D-(KLAKLAK)(2) and Bcl-2 antisense oligodeoxynucleotide G3139 for enhanced anticancer therapy.
Molecular pharmaceutics 2009;6(3):971-7.
2009: Tamer Elbayoumi; Vladimir P Torchilin
Tumor-targeted nanomedicines: enhanced antitumor efficacy in vivo of doxorubicin-loaded, long-circulating liposomes modified with cancer-specific monoclonal antibody.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(6):1973-80.
2009: Tiziana Musacchio; Valentino Laquintana; Andrea Latrofa; Giuseppe Trapani; Vladimir P Torchilin
PEG-PE micelles loaded with paclitaxel and surface-modified by a PBR-ligand: synergistic anticancer effect.
Molecular pharmaceutics 2009;6(2):468-79.
2009: Prashanth K Jayanna; Vladimir P Torchilin; Valery A Petrenko
Liposomes targeted by fusion phage proteins.
Nanomedicine : nanotechnology, biology, and medicine 2009;5(1):83-9.
2009: Juan Sebastián Pappalardo; Valeria Quattrocchi; Cecilia Langellotti; Sebastián Di Giacomo; Victoria Gnazzo; Valeria Olivera; Gabriela Calamante; Patricia I Zamorano; Tatyana S Levchenko; Vladimir P Torchilin
Improved transfection of spleen-derived antigen-presenting cells in culture using TATp-liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2009;134(1):41-6.
2009: Aristarchos Papagiannaros; Amit Kale; Tatiana S Levchenko; Dmitriy A Mongayt; William C Hartner; Vladimir P Torchilin
Near infrared planar tumor imaging and quantification using nanosized Alexa 750-labeled phospholipid micelles.
International journal of nanomedicine 2009;4():123-31.
2009: Tamer Elbayoumi; Vladimir P Torchilin
Tumor-specific anti-nucleosome antibody improves therapeutic efficacy of doxorubicin-loaded long-circulating liposomes against primary and metastatic tumor in mice.
Molecular pharmaceutics 2009;6(1):246-54.
2009: Y T Ko; William C Hartner; A Kale; Vladimir P Torchilin
Gene delivery into ischemic myocardium by double-targeted lipoplexes with anti-myosin antibody and TAT peptide.
Gene therapy 2009;16(1):52-9.
2008: Tamer Elbayoumi; Vladimir P Torchilin
Liposomes for targeted delivery of antithrombotic drugs.
Expert opinion on drug delivery 2008;5(11):1185-98.
2008: Gerard G M D'Souza; Tao Wang; Karen Rockwell; Vladimir P Torchilin
Surface modification of pharmaceutical nanocarriers with ascorbate residues improves their tumor-cell association and killing and the cytotoxic action of encapsulated paclitaxel in vitro.
Pharmaceutical research 2008;25(11):2567-72.
2008: Vladimir P Torchilin
Preface. Fifth International Nanomedicine and Drug Delivery Symposium (NanoDDS'07).
Journal of controlled release : official journal of the Controlled Release Society 2008;130(2):97.
2008: William R Hendee; Kevin Cleary; Richard L Ehman; Gary D Fullerton; Warren Grundfest; John Haller; Christine A Kelley; Anne E Meyer; Robert F Murphy; William Phillips; Vladimir P Torchilin
Bioengineering and Imaging Research Opportunities Workshop V: a summary on Imaging and Characterizing Structure and Function in Native and Engineered Tissues.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(9):779-84.
2008: Rupa R Sawant; Rishikesh M Sawant; Vladimir P Torchilin
Mixed PEG-PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: improved drug solubilization and enhanced in vitro cytotoxicity.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(1):51-7.
2008: William R Hendee; Kevin Cleary; Richard L Ehman; Gary D Fullerton; Warren Grundfest; John Haller; Christine Kelley; Anne Meyer; Robert F Murphy; William Phillips; Vladimir P Torchilin
Bioengineering and Imaging Research Opportunities Workshop V: a white paper on imaging and characterizing structure and function in native and engineered tissues.
Medical physics 2008;35(8):3428-35.
2008: Rishikesh M Sawant; Michael B Cohen; Vladimir P Torchilin; Oskar W Rokhlin
Prostate cancer-specific monoclonal antibody 5D4 significantly enhances the cytotoxicity of doxorubicin-loaded liposomes against target cells in vitro.
Journal of drug targeting 2008;16(7):601-4.
2008: Rupa R Sawant; Rishikesh M Sawant; Amit Kale; Vladimir P Torchilin
The architecture of ligand attachment to nanocarriers controls their specific interaction with target cells.
Journal of drug targeting 2008;16(7):596-600.
2008: William R Hendee; Kevin Cleary; Richard L Ehman; Gary D Fullerton; Warren Grundfest; John Haller; Christine A Kelley; Anne E Meyer; Robert F Murphy; William Phillips; Vladimir P Torchilin
Bioengineering and imaging research opportunities workshop V: summary of findings on imaging and characterizing structure and function in native and engineered tissues.
Radiology 2008;248(2):342-7.
2008: William R Hendee; Kevin Cleary; Richard L Ehman; Gary D Fullerton; Warren Grundfest; John Haller; Christine Kelley; Anne E Meyer; Robert F Murphy; William Phillips; Vladimir P Torchilin
Bioengineering and imaging research opportunities workshop V: a summary.
Annals of biomedical engineering 2008;36(8):1315-21.
2008: Sarathi Boddapati; Gerard G M D'Souza; Suna Erdogan; Vladimir P Torchilin; Volkmar Weissig
Organelle-targeted nanocarriers: specific delivery of liposomal ceramide to mitochondria enhances its cytotoxicity in vitro and in vivo.
Nano letters 2008;8(8):2559-63.
2008: Igor Skidan; Parita Dholakia; Vladimir P Torchilin
Photodynamic therapy of experimental B-16 melanoma in mice with tumor-targeted 5,10,15,20-tetraphenylporphin-loaded PEG-PE micelles.
Journal of drug targeting 2008;16(6):486-93.
2008: Anshul Agarwal; Yuri M Lvov; Rishikesh Sawant; Vladimir P Torchilin
Stable nanocolloids of poorly soluble drugs with high drug content prepared using the combination of sonication and layer-by-layer technology.
Journal of controlled release : official journal of the Controlled Release Society 2008;128(3):255-60.
2008: Tamer Elbayoumi; Vladimir P Torchilin
Tumor-specific antibody-mediated targeted delivery of Doxil reduces the manifestation of auricular erythema side effect in mice.
International journal of pharmaceutics 2008;357(1-2):272-9.
2008: Kejian Yang; Barbara J Whalen; Rebecca Tirabassi; Liisa K Selin; Tatyana S Levchenko; Vladimir P Torchilin; Edward Kislauskis; Dennis L Guberski
A DNA vaccine prime followed by a liposome-encapsulated protein boost confers enhanced mucosal immune responses and protection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(9):6159-67.
2008: Julia Y Ljubimova; Manabu Fujita; Alexander V Ljubimov; Vladimir P Torchilin; Keith L Black; Eggehard Holler
Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery.
Nanomedicine (London, England) 2008;3(2):247-65.
2008: Suna Erdogan; Zdravka O Medarova; Aruna Roby; Anna Moore; Vladimir P Torchilin
Enhanced tumor MR imaging with gadolinium-loaded polychelating polymer-containing tumor-targeted liposomes.
Journal of magnetic resonance imaging : JMRI 2008;27(3):574-80.
2008: Christian Matthäus; Amit Kale; Tatyana Chernenko; Vladimir P Torchilin; Max Diem
New ways of imaging uptake and intracellular fate of liposomal drug carrier systems inside individual cells, based on Raman microscopy.
Molecular pharmaceutics 2008;5(2):287-93.
2008: Vladimir P Torchilin
Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers.
Advanced drug delivery reviews 2008;60(4-5):548-58.
2008: Vladimir P Torchilin
Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery.
Biopolymers 2008;90(5):604-10.
2007: Vladimir P Torchilin
Nanocarriers.
Pharmaceutical research 2007;24(12):2333-4.
2007: Tamer Elbayoumi; Vladimir P Torchilin
Enhanced cytotoxicity of monoclonal anticancer antibody 2C5-modified doxorubicin-loaded PEGylated liposomes against various tumor cell lines.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;32(3):159-68.
2007: Daya D Verma; William C Hartner; Vineet Thakkar; Tatiana S Levchenko; Vladimir P Torchilin
Protective effect of coenzyme Q10-loaded liposomes on the myocardium in rabbits with an acute experimental myocardial infarction.
Pharmaceutical research 2007;24(11):2131-7.
2007: Amit Kale; Vladimir P Torchilin
Enhanced transfection of tumor cells in vivo using "Smart" pH-sensitive TAT-modified pegylated liposomes.
Journal of drug targeting 2007;15(7-8):538-45.
2007: Bhawna Gupta; Vladimir P Torchilin
Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice.
Cancer immunology, immunotherapy : CII 2007;56(8):1215-23.
2007: Aruna Roby; Suna Erdogan; Vladimir P Torchilin
Enhanced in vivo antitumor efficacy of poorly soluble PDT agent, meso-tetraphenylporphine, in PEG-PE-based tumor-targeted immunomicelles.
Cancer biology & therapy 2007;6(7):1136-42.
2007: Amit Kale; Vladimir P Torchilin
Design, synthesis, and characterization of pH-sensitive PEG-PE conjugates for stimuli-sensitive pharmaceutical nanocarriers: the effect of substitutes at the hydrazone linkage on the ph stability of PEG-PE conjugates.
Bioconjugate chemistry 2007;18(2):363-70.
2007: Amit Kale; Vladimir P Torchilin
"Smart" drug carriers: PEGylated TATp-modified pH-sensitive liposomes.
Journal of liposome research 2007;17(3-4):197-203.
2007: Bhawna Gupta; Tatiana S Levchenko; Vladimir P Torchilin
TAT peptide-modified liposomes provide enhanced gene delivery to intracranial human brain tumor xenografts in nude mice.
Oncology research 2007;16(8):351-9.
2007: Vladimir P Torchilin
Targeted pharmaceutical nanocarriers for cancer therapy and imaging.
The AAPS journal 2007;9(2):E128-47.
2007: Tamer Elbayoumi; Santosh Pabba; Aruna Roby; Vladimir P Torchilin
Antinucleosome antibody-modified liposomes and lipid-core micelles for tumor-targeted delivery of therapeutic and diagnostic agents.
Journal of liposome research 2007;17(1):1-14.
2007: Vladimir P Torchilin
Micellar nanocarriers: pharmaceutical perspectives.
Pharmaceutical research 2007;24(1):1-16.
2006: Vladimir P Torchilin
Multifunctional nanocarriers.
Advanced drug delivery reviews 2006;58(14):1532-55.
2006: Vladimir P Torchilin
Application of nanomedical approaches in experimental and clinical oncology.
Anti-cancer agents in medicinal chemistry 2006;6(6):501.
2006: Tamer Elbayoumi; Vladimir P Torchilin
Enhanced accumulation of long-circulating liposomes modified with the nucleosome-specific monoclonal antibody 2C5 in various tumours in mice: gamma-imaging studies.
European journal of nuclear medicine and molecular imaging 2006;33(10):1196-205.
2006: Suna Erdogan; Aruna Roby; Vladimir P Torchilin
Enhanced tumor visualization by gamma-scintigraphy with 111In-labeled polychelating-polymer-containing immunoliposomes.
Molecular pharmaceutics 2006;3(5):525-30.
2006: Rishikesh M Sawant; J P Hurley; Stefano Salmaso; Amit Kale; E Tolcheva; Tatiana S Levchenko; Vladimir P Torchilin
"SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers.
Bioconjugate chemistry 2006;17(4):943-9.
2006: Rupa D Dabholkar; Rishikesh M Sawant; Dmitriy A Mongayt; Padma V Devarajan; Vladimir P Torchilin
Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux.
International journal of pharmaceutics 2006;315(1-2):148-57.
2006: Daya D Verma; Tatiana S Levchenko; Eugene A Bernstein; Dmitriy A Mongayt; Vladimir P Torchilin
ATP-loaded immunoliposomes specific for cardiac myosin provide improved protection of the mechanical functions of myocardium from global ischemia in an isolated rat heart model.
Journal of drug targeting 2006;14(5):273-80.
2006: Chunling Zhang; Ning Tang; XingJun Liu; Wei Liang; Wei Xu; Vladimir P Torchilin
siRNA-containing liposomes modified with polyarginine effectively silence the targeted gene.
Journal of controlled release : official journal of the Controlled Release Society 2006;112(2):229-39.
2006: Aruna Roby; Suna Erdogan; Vladimir P Torchilin
Solubilization of poorly soluble PDT agent, meso-tetraphenylporphin, in plain or immunotargeted PEG-PE micelles results in dramatically improved cancer cell killing in vitro.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2006;62(3):235-40.
2006: Bhawna Gupta; Vladimir P Torchilin
Transactivating transcriptional activator-mediated drug delivery.
Expert opinion on drug delivery 2006;3(2):177-90.
2006: Vladimir P Torchilin
Recent approaches to intracellular delivery of drugs and DNA and organelle targeting.
Annual review of biomedical engineering 2006;8():343-75.
2006: Suna Erdogan; Aruna Roby; Rishikesh M Sawant; Jim Hurley; Vladimir P Torchilin
Gadolinium-loaded polychelating polymer-containing cancer cell-specific immunoliposomes.
Journal of liposome research 2006;16(1):45-55.
2005: L Mu; Tamer Elbayoumi; Vladimir P Torchilin
Mixed micelles made of poly(ethylene glycol)-phosphatidylethanolamine conjugate and d-alpha-tocopheryl polyethylene glycol 1000 succinate as pharmaceutical nanocarriers for camptothecin.
International journal of pharmaceutics 2005;306(1-2):142-9.
2005: Daya D Verma; William C Hartner; Tatiana S Levchenko; Eugene A Bernstein; Vladimir P Torchilin
ATP-loaded liposomes effectively protect the myocardium in rabbits with an acute experimental myocardial infarction.
Pharmaceutical research 2005;22(12):2115-20.
2005: Daya D Verma; Tatiana S Levchenko; Eugene A Bernstein; Vladimir P Torchilin
ATP-loaded liposomes effectively protect mechanical functions of the myocardium from global ischemia in an isolated rat heart model.
Journal of controlled release : official journal of the Controlled Release Society 2005;108(2-3):460-71.
2005: W Matthew Leevy; Seth T Gammon; Tatiana Levchenko; David D Daranciang; Oscar Murillo; Vladimir P Torchilin; David Piwnica-Worms; James E Huettner; George W Gokel
Structure-activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells.
Organic & biomolecular chemistry 2005;3(19):3544-50.
2005: Vladimir P Torchilin
Lipid-core micelles for targeted drug delivery.
Current drug delivery 2005;2(4):319-27.
2005: Muneeb Ahmed; Anatoly N Lukyanov; Vladimir P Torchilin; Herve Tournier; Anatoly N Schneider; S Nahum Goldberg
Combined radiofrequency ablation and adjuvant liposomal chemotherapy: effect of chemotherapeutic agent, nanoparticle size, and circulation time.
Journal of vascular and interventional radiology : JVIR 2005;16(10):1365-71.
2005: Bhawna Gupta; Tatiana S Levchenko; Dmitriy A Mongayt; Vladimir P Torchilin
Monoclonal antibody 2C5-mediated binding of liposomes to brain tumor cells in vitro and in subcutaneous tumor model in vivo.
Journal of drug targeting 2005;13(6):337-43.
2005: Mark Stroh; John P Zimmer; Dan G Duda; Tatyana S Levchenko; Kenneth S Cohen; Edward B Brown; David T Scadden; Vladimir P Torchilin; Moungi G Bawendi; Dai Fukumura; Rakesh K Jain
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo.
Nature medicine 2005;11(6):678-82.
2005: Muneeb Ahmed; Zhengjun Liu; Anatoly N Lukyanov; Sabina Signoretti; Clare Horkan; Wayne L Monsky; Vladimir P Torchilin; S Nahum Goldberg
Combination radiofrequency ablation with intratumoral liposomal doxorubicin: effect on drug accumulation and coagulation in multiple tissues and tumor types in animals.
Radiology 2005;235(2):469-77.
2005: Bhawna Gupta; Tatiana S Levchenko; Vladimir P Torchilin
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides.
Advanced drug delivery reviews 2005;57(4):637-51.
2005: Vladimir P Torchilin
Recent advances with liposomes as pharmaceutical carriers.
Nature reviews. Drug discovery 2005;4(2):145-60.
2005: Vladimir P Torchilin
Fluorescence microscopy to follow the targeting of liposomes and micelles to cells and their intracellular fate.
Advanced drug delivery reviews 2005;57(1):95-109.
2005: Sarathi Boddapati; Pakamas Tongcharoensirikul; Robert N Hanson; Gerard G M D'Souza; Vladimir P Torchilin; Volkmar Weissig
Mitochondriotropic liposomes.
Journal of liposome research 2005;15(1-2):49-58.
2005: Junping Wang; Dmitriy A Mongayt; Vladimir P Torchilin
Polymeric micelles for delivery of poorly soluble drugs: preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids.
Journal of drug targeting 2005;13(1):73-80.
2004: Wei Liang; Dariush Davalian; Vladimir P Torchilin
Interaction of a novel peptoid enhancer--arginine oligomer with bovine submaxillary mucin.
Yao xue xue bao = Acta pharmaceutica Sinica 2004;39(12):1011-7.
2004: Anatoly N Lukyanov; Tamer Elbayoumi; Ananthsrinivas R Chakilam; Vladimir P Torchilin
Tumor-targeted liposomes: doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody.
Journal of controlled release : official journal of the Controlled Release Society 2004;100(1):135-44.
2004: Anatoly N Lukyanov; Vladimir P Torchilin
Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs.
Advanced drug delivery reviews 2004;56(9):1273-89.
2004: W Liang; Tatiana S Levchenko; Vladimir P Torchilin
Encapsulation of ATP into liposomes by different methods: optimization of the procedure.
Journal of microencapsulation 2004;21(3):251-61.
2004: Junping Wang; Dmitriy A Mongayt; Anatoly N Lukyanov; Tatiana S Levchenko; Vladimir P Torchilin
Preparation and in vitro synergistic anticancer effect of vitamin K3 and 1,8-diazabicyclo[5,4,0]undec-7-ene in poly(ethylene glycol)-diacyllipid micelles.
International journal of pharmaceutics 2004;272(1-2):129-35.
2004: Reto Wettstein; Amy Tsai; Dominique Erni; Anatoly N Lukyanov; Vladimir P Torchilin; Marcos Intaglietta
Improving microcirculation is more effective than substitution of red blood cells to correct metabolic disorder in experimental hemorrhagic shock.
Shock (Augusta, Ga.) 2004;21(3):235-40.
2004: Anatoly N Lukyanov; William C Hartner; Vladimir P Torchilin
Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits.
Journal of controlled release : official journal of the Controlled Release Society 2004;94(1):187-93.
2004: Wei Liang; Tatiana S Levchenko; Ban-An Khaw; Vladimir P Torchilin
ATP-containing immunoliposomes specific for cardiac myosin.
Current drug delivery 2004;1(1):1-7.
2004: Anatoly N Lukyanov; Rishikesh M Sawant; William C Hartner; Vladimir P Torchilin
PEGylated dextran as long-circulating pharmaceutical carrier.
Journal of biomaterials science. Polymer edition 2004;15(5):621-30.
2003: Muneeb Ahmed; Wayne L Monsky; Geoffrey D Girnun; Anatoly N Lukyanov; Giuseppe D'Ippolito; Jonathan B Kruskal; Keith E Stuart; Vladimir P Torchilin; S Nahum Goldberg
Radiofrequency thermal ablation sharply increases intratumoral liposomal doxorubicin accumulation and tumor coagulation.
Cancer research 2003;63(19):6327-33.
2003: Gerard G M D'Souza; Ram Rammohan; Shing-Ming Cheng; Vladimir P Torchilin; Volkmar Weissig
DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells.
Journal of controlled release : official journal of the Controlled Release Society 2003;92(1-2):189-97.
2003: Carmen Lizano; Volkmar Weissig; Vladimir P Torchilin; Pilar Sancho; Ana Isabel García-Pérez; Montserrat Pinilla
In vivo biodistribution of erythrocytes and polyethyleneglycol-phosphatidylethanolamine micelles carrying the antitumour agent dequalinium.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2003;56(2):153-7.
2003: Anatoly N Lukyanov; Zhonggao Gao; Vladimir P Torchilin
Micelles from polyethylene glycol/phosphatidylethanolamine conjugates for tumor drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2003;91(1-2):97-102.
2003: Minoru Asahi; Ram Rammohan; Toshihisa Sumii; Xiaoying Wang; Robert Jan Pauw; Volkmar Weissig; Vladimir P Torchilin; Eng H Lo
Antiactin-targeted immunoliposomes ameliorate tissue plasminogen activator-induced hemorrhage after focal embolic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(8):895-9.
2003: Vladimir P Torchilin; Anatoly N Lukyanov; Zhonggao Gao; Brigitte Papahadjopoulos-Sternberg
Immunomicelles: targeted pharmaceutical carriers for poorly soluble drugs.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6039-44.
2003: Vladimir P Torchilin; Tatiana S Levchenko
TAT-liposomes: a novel intracellular drug carrier.
Current protein & peptide science 2003;4(2):133-40.
2003: Vladimir P Torchilin; Anatoly N Lukyanov
Peptide and protein drug delivery to and into tumors: challenges and solutions.
Drug discovery today 2003;8(6):259-66.
2003: Vladimir P Torchilin; Tatiana S Levchenko; Ram Rammohan; Natalia Volodina; Brigitte Papahadjopoulos-Sternberg; Gerard G M D'Souza
Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1972-7.
2003: Zhonggao Gao; Anatoly N Lukyanov; A R Chakilam; Vladimir P Torchilin
PEG-PE/phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing.
Journal of drug targeting 2003;11(2):87-92.
2003: Tatiana S Levchenko; Ram Rammohan; Natalia Volodina; Vladimir P Torchilin
Tat peptide-mediated intracellular delivery of liposomes.
Methods in enzymology 2003;372():339-49.
2002: Robert B Campbell; Dai Fukumura; Edward B Brown; Laureen M Mazzola; Yotaro Izumi; Rakesh K Jain; Vladimir P Torchilin; Lance L Munn
Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors.
Cancer research 2002;62(23):6831-6.
2002: Vladimir P Torchilin; Ban-An Khaw; Volkmar Weissig
Intracellular targets for DNA delivery: nuclei and mitochondria.
Somatic cell and molecular genetics 2002;27(1-6):49-64.
2002: Anatoly N Lukyanov; Zhonggao Gao; Laureen Mazzola; Vladimir P Torchilin
Polyethylene glycol-diacyllipid micelles demonstrate increased acculumation in subcutaneous tumors in mice.
Pharmaceutical research 2002;19(10):1424-9.
2002: Wayne L Monsky; Jonathan B Kruskal; Anatoly N Lukyanov; Geoffrey D Girnun; Muneeb Ahmed; G Scott Gazelle; Juan Carlos Huertas; Keith E Stuart; Vladimir P Torchilin; S Nahum Goldberg
Radio-frequency ablation increases intratumoral liposomal doxorubicin accumulation in a rat breast tumor model.
Radiology 2002;224(3):823-9.
2002: Tatiana S Levchenko; Ram Rammohan; Anatoly N Lukyanov; Kathleen R Whiteman; Vladimir P Torchilin
Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating.
International journal of pharmaceutics 2002;240(1-2):95-102.
2002: Vladimir P Torchilin
PEG-based micelles as carriers of contrast agents for different imaging modalities.
Advanced drug delivery reviews 2002;54(2):235-52.
2002: Vladimir P Torchilin
TAT peptide-modified liposomes for intracellular delivery of drugs and DNA.
Cellular & molecular biology letters 2002;7(2):265-7.
2001: Vladimir P Torchilin; Tatiana S Levchenko; Kathleen R Whiteman; A A Yaroslavov; Aristidis M Tsatsakis; Apostolos Rizos; E V Michailova; Mikhail I Shtilman
Amphiphilic poly-N-vinylpyrrolidones: synthesis, properties and liposome surface modification.
Biomaterials 2001;22(22):3035-44.
2001: Volkmar Weissig; Gerard G M D'Souza; Vladimir P Torchilin
DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria.
Journal of controlled release : official journal of the Controlled Release Society 2001;75(3):401-8.
2001: Vladimir P Torchilin; LZ Iakoubov; Z Estrov
Antinuclear autoantibodies as potential antineoplastic agents.
Trends in immunology 2001;22(8):424-7.
2001: Vladimir P Torchilin; Ram Rammohan; Volkmar Weissig; Tatiana S Levchenko
TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8786-91.
2001: Ban-An Khaw; J daSilva; I Vural; J Narula; Vladimir P Torchilin
Intracytoplasmic gene delivery for in vitro transfection with cytoskeleton-specific immunoliposomes.
Journal of controlled release : official journal of the Controlled Release Society 2001;75(1-2):199-210.
2001: Volkmar Weissig; Vladimir P Torchilin
Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems.
Advanced drug delivery reviews 2001;49(1-2):127-49.
2001: Vladimir P Torchilin
Structure and design of polymeric surfactant-based drug delivery systems.
Journal of controlled release : official journal of the Controlled Release Society 2001;73(2-3):137-72.
2001: G P Samokhin; Dmitriy A Mongayt; LZ Iakoubov; Tatiana S Levchenko; Vladimir P Torchilin
Negatively charged polymers protect antinuclear antibody against inactivation by acylating agents.
Analytical biochemistry 2001;292(2):245-9.
2001: Vladimir P Torchilin; Tatiana S Levchenko; Anatoly N Lukyanov; Ban-An Khaw; A L Klibanov; Ram Rammohan; G P Samokhin; Kathleen R Whiteman
p-Nitrophenylcarbonyl-PEG-PE-liposomes: fast and simple attachment of specific ligands, including monoclonal antibodies, to distal ends of PEG chains via p-nitrophenylcarbonyl groups.
Biochimica et biophysica acta 2001;1511(2):397-411.
2001: Kathleen R Whiteman; V Subr; K Ulbrich; Vladimir P Torchilin
Poly(Hpma)-coated liposomes demonstrate prolonged circulation in mice.
Journal of liposome research 2001;11(2-3):153-64.
2001: Volkmar Weissig; Vladimir P Torchilin
Towards mitochondrial gene therapy: DQAsomes as a strategy.
Journal of drug targeting 2001;9(1):1-13.
2000: Vladimir P Torchilin
Drug targeting.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;11 Suppl 2():S81-91.
2000: Volkmar Weissig; Carmen Lizano; Vladimir P Torchilin
Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes.
Drug delivery 2000;7(1):1-5.
1999: Wayne L Monsky; Dai Fukumura; Takeshi Gohongi; M Ancukiewcz; H A Weich; Vladimir P Torchilin; F Yuan; Rakesh K Jain
Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor.
Cancer research 1999;59(16):4129-35.
1999: Vladimir P Torchilin
Biotin-conjugated polychelating agent.
Bioconjugate chemistry 1999;10(1):146-9.
1999: Vladimir P Torchilin; M D Frank-Kamenetsky; GL Wolf
CT visualization of blood pool in rats by using long-circulating, iodine-containing micelles.
Academic radiology 1999;6(1):61-5.
1998: Volkmar Weissig; Kathleen R Whiteman; Vladimir P Torchilin
Accumulation of protein-loaded long-circulating micelles and liposomes in subcutaneous Lewis lung carcinoma in mice.
Pharmaceutical research 1998;15(10):1552-6.
1998: S K Hobbs; Wayne L Monsky; F Yuan; W G Roberts; L Griffith; Vladimir P Torchilin; Rakesh K Jain
Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4607-12.
1998: VS Trubetskoy; Kathleen R Whiteman; Vladimir P Torchilin; GL Wolf
Massage-induced release of subcutaneously injected liposome-encapsulated drugs to the blood.
Journal of controlled release : official journal of the Controlled Release Society 1998;50(1-3):13-9.
1998: S Dalkara; Artiom Petrov; VS Trubetskoy; Ban-An Khaw; Vladimir P Torchilin
Disulfide cross-linked Fab-aggregates: preparation and biodistribution.
Journal of drug targeting 1998;6(1):45-52.
1998: LZ Iakoubov; Vladimir P Torchilin
Nucleosome-releasing treatment makes surviving tumor cells better targets for nucleosome-specific anticancer antibodies.
Cancer detection and prevention 1998;22(5):470-5.
1998: Vladimir P Torchilin
Polymer-coated long-circulating microparticulate pharmaceuticals.
Journal of microencapsulation 1998;15(1):1-19.
1997: LZ Iakoubov; Vladimir P Torchilin
A novel class of antitumor antibodies: nucleosome-restricted antinuclear autoantibodies (ANA) from healthy aged nonautoimmune mice.
Oncology research 1997;9(8):439-46.
1997: VS Trubetskoy; G Scott Gazelle; GL Wolf; Vladimir P Torchilin
Block-copolymer of polyethylene glycol and polylysine as a carrier of organic iodine: design of long-circulating particulate contrast medium for X-ray computed tomography.
Journal of drug targeting 1997;4(6):381-8.
1996: Vladimir P Torchilin
Affinity liposomes in vivo: factors influencing target accumulation.
Journal of molecular recognition : JMR 1996;9(5-6):335-46.
1996: VS Trubetskoy; M D Frank-Kamenetsky; Kathleen R Whiteman; GL Wolf; Vladimir P Torchilin
Stable polymeric micelles: lymphangiographic contrast media for gamma scintigraphy and magnetic resonance imaging.
Academic radiology 1996;3(3):232-8.
1996: Vladimir P Torchilin; J Narula; E Halpern; B A Khaw
Poly(ethylene glycol)-coated anti-cardiac myosin immunoliposomes: factors influencing targeted accumulation in the infarcted myocardium.
Biochimica et biophysica acta 1996;1279(1):75-83.
1995: Vladimir P Torchilin; VS Trubetskoy; Kathleen R Whiteman; Paolo Caliceti; P Ferruti; F M Veronese
New synthetic amphiphilic polymers for steric protection of liposomes in vivo.
Journal of pharmaceutical sciences 1995;84(9):1049-53.
1995: F Yuan; Marc Dellian; Dai Fukumura; M Leunig; David A Berk; Vladimir P Torchilin; Rakesh K Jain
Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.
Cancer research 1995;55(17):3752-6.
1995: VS Trubetskoy; Vladimir P Torchilin
Fast and specific labeling of antibody fragments with multiple atoms of heavy metal radioisotopes.
Analytical biochemistry 1995;229(2):345-7.
1995: Jagat Narula; Artiom Petrov; C Bianchi; C C Ditlow; B C Lister; J Dilley; I Pieslak; F W Chen; Vladimir P Torchilin; Ban-An Khaw
Noninvasive localization of experimental atherosclerotic lesions with mouse/human chimeric Z2D3 F(ab')2 specific for the proliferating smooth muscle cells of human atheroma. Imaging with conventional and negative charge-modified antibody fragments.
Circulation 1995;92(3):474-84.
1995: LZ Iakoubov; O Rokhlin; Vladimir P Torchilin
Anti-nuclear autoantibodies of the aged reactive against the surface of tumor but not normal cells.
Immunology letters 1995;47(1-2):147-9.
1995: Jagat Narula; Vladimir P Torchilin; Artiom Petrov; S Khaw; VS Trubetskoy; S M O'Donnell; N D Nossiff; Ban-An Khaw
In vivo targeting of acute myocardial infarction with negative-charge, polymer-modified antimyosin antibody: use of different cross-linkers.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 1995;2(1):26-34.
1995: VS Trubetskoy; J A Cannillo; A Milshtein; GL Wolf; Vladimir P Torchilin
Controlled delivery of Gd-containing liposomes to lymph nodes: surface modification may enhance MRI contrast properties.
Magnetic resonance imaging 1995;13(1):31-7.
1994: Vladimir P Torchilin; M I Shtilman; VS Trubetskoy; Kathleen R Whiteman; A M Milstein
Amphiphilic vinyl polymers effectively prolong liposome circulation time in vivo.
Biochimica et biophysica acta 1994;1195(1):181-4.
1994: Vladimir P Torchilin; V Omelyanenko; M I Papisov; Alexei Bogdanov; VS Trubetskoy; J N Herron; C A Gentry
Poly(ethylene glycol) on the liposome surface: on the mechanism of polymer-coated liposome longevity.
Biochimica et biophysica acta 1994;1195(1):11-20.
1994: Vladimir P Torchilin
Immunoliposomes and PEGylated immunoliposomes: possible use for targeted delivery of imaging agents.
ImmunoMethods 1994;4(3):244-58.
1993: VS Trubetskoy; Jagat Narula; Ban-An Khaw; Vladimir P Torchilin
Chemically optimized antimyosin Fab conjugates with chelating polymers: importance of the nature of the protein-polymer single site covalent bond for biodistribution and infarction localization.
Bioconjugate chemistry 1993;4(4):251-5.
1992: Vladimir P Torchilin; V Omelyanenko; A N Lukyanov
Temperature-dependent aggregation of pH-sensitive phosphatidyl ethanolamine-oleic acid-cholesterol liposomes as measured by fluorescent spectroscopy.
Analytical biochemistry 1992;207(1):109-13.
1992: Svetlana Glushakova; V Omelyanenko; I S Lukashevitch; A A Bogdanov; A B Moshnikova; A T Kozytch; Vladimir P Torchilin
The fusion of artificial lipid membranes induced by the synthetic arenavirus 'fusion peptide'.
Biochimica et biophysica acta 1992;1110(2):202-8.
1992: Vladimir P Torchilin; A N Lukyanov; A L Klibanov; V Omelyanenko
Interaction between oleic acid-containing pH-sensitive and plain liposomes. Fluorescent spectroscopy studies.
FEBS letters 1992;305(3):185-8.
1992: Vladimir P Torchilin; A L Klibanov; L Huang; S O'Donnell; N D Nossiff; Ban-An Khaw
Targeted accumulation of polyethylene glycol-coated immunoliposomes in infarcted rabbit myocardium.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(9):2716-9.
1991: A L Klibanov; Ban-An Khaw; N Nossiff; S M O'Donnell; L Huang; M A Slinkin; Vladimir P Torchilin
Targeting of macromolecular carriers and liposomes by antibodies to myosin heavy chain.
The American journal of physiology 1991;261(4 Suppl):60-5.
1991: Ban-An Khaw; A Klibanov; S M O'Donnell; T Saito; N Nossiff; M A Slinkin; J B Newell; Harry W Strauss; Vladimir P Torchilin
Gamma imaging with negatively charge-modified monoclonal antibody: modification with synthetic polymers.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(9):1742-51.
1991: M A Slinkin; A L Klibanov; Vladimir P Torchilin
Terminal-modified polylysine-based chelating polymers: highly efficient coupling to antibody with minimal loss in immunoreactivity.
Bioconjugate chemistry 1991;2(5):342-8.
1991: Alexey A Bogdanov; L V Gordeeva; B A Baibakov; Leonid Margolis; Vladimir P Torchilin
Restoration of adhesive potentials of Ehrlich ascites carcinoma cells by modification of plasma membrane.
Journal of cellular physiology 1991;147(1):182-90.
1991: Svetlana Glushakova; V G Omel'ianenko; Igor S Lukashevich; Alexei Bogdanov; A B Moshnikova; Alexander A Kozhich; Vladimir P Torchilin
[Fusion of artificial lipid membranes induced by synthetic "fusion peptide" of arenaviruses].
Biokhimii͡a (Moscow, Russia) 1991;56(4):579-88.
1990: M A Slinkin; A L Klibanov; Ban-An Khaw; Vladimir P Torchilin
Succinylated polylysine as a possible link between an antibody molecule and deferoxamine.
Bioconjugate chemistry 1990;1(4):291-5.
1989: N M Mukhamedova; S K Obukhov; M A Slinkin; A L Klibanov; Vladimir P Torchilin
[The chemical modification of immunoglobulins for accelerating their elimination from the blood flow during radioimmunodiagnosis].
Biulleten' eksperimental'noĭ biologii i meditsiny 1989;108(12):705-7.
1989: Sergei M Danilov; A V Martynov; A L Klibanov; M A Slinkin; A G Malov; V B Sergienko; Vladimir R Muzykantov; Vladimir P Torchilin
Radioimmunoimaging of lung vessels: an approach using indium-111-labeled monoclonal antibody to angiotensin-converting enzyme.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1989;30(10):1686-92.
1989: Alexey A Bogdanov; L V Gordeeva; Vladimir P Torchilin; Leonid Margolis
Lectin-bearing liposomes: differential binding to normal and to transformed mouse fibroblasts.
Experimental cell research 1989;181(2):362-74.
1989: Ban-An Khaw; Vladimir P Torchilin; A L Klibanov; N D Nossiff; J B Powers; Harry W Strauss; E Haber
Modification of monoclonal antimyosin antibody: enhanced specificity of localization and scintigraphic visualization in acute experimental myocardial infarction.
Journal of molecular and cellular cardiology 1989;21 Suppl 1():31-5.
1988: L V Gordeeva; Alexey A Bogdanov; B A Baibakov; Vladimir P Torchilin; Leonid Margolis
Adhesion defect of ascites cells corrected with membrane-bound attachment molecules.
FEBS letters 1988;241(1-2):185-7.
1988: A L Klibanov; A V Martynov; M A Slinkin; Mikhail Smirnov; Vladimir R Muzykantov; Sergei M Danilov; Vladimir P Torchilin
Blood clearance of radiolabeled antibody: enhancement by lactosamination and treatment with biotin-avidin or anti-mouse IgG antibodies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1988;29(12):1951-6.
1988: V S Trubetskoy; E V Dormeneva; V P Tsibulsky; V S Repin; Vladimir P Torchilin
Use of enzyme label for quantitative evaluation of liposome adhesion on cell surface: studies with J774 macrophage monolayers.
Analytical biochemistry 1988;172(1):185-9.
1988: Alexei Bogdanov; A L Klibanov; Vladimir P Torchilin
Protein immobilization on the surface of liposomes via carbodiimide activation in the presence of N-hydroxysulfosuccinimide.
FEBS letters 1988;231(2):381-4.
1988: O V Trubetskaya; V S Trubetskoy; S P Domogatsky; A V Rudin; N V Popov; Sergei M Danilov; M N Nikolayeva; A L Klibanov; Vladimir P Torchilin
Monoclonal antibody to human endothelial cell surface internalization and liposome delivery in cell culture.
FEBS letters 1988;228(1):131-4.
1987: VV Tertov; AN Orekhov; S A Kudryashov; A L Klibanov; N N Ivanov; Vladimir P Torchilin; Vladimir N Smirnov
Cyclic nucleotides and atherosclerosis: studies in primary culture of human aortic cells.
Experimental and molecular pathology 1987;47(3):377-89.
1987: Vladimir P Torchilin; A L Klibanov; N D Nossiff; M A Slinkin; Harry W Strauss; E Haber; Vladimir N Smirnov; Ban-An Khaw
Monoclonal antibody modification with chelate-linked high-molecular-weight polymers: major increases in polyvalent cation binding without loss of antigen binding.
Hybridoma 1987;6(3):229-40.
1986: Vladimir P Torchilin; Ban-An Khaw; A L Klibanov; M A Slinkin; E Haber
[Modification of monoclonal antibodies by polymers possessing chelating properties].
Biulleten' eksperimental'noĭ biologii i meditsiny 1986;102(7):63-5.
1986: Volkmar Weissig; Jürgen Lasch; A L Klibanov; Vladimir P Torchilin
A new hydrophobic anchor for the attachment of proteins to liposomal membranes.
FEBS letters 1986;202(1):86-90.
1985: A L Klibanov; Vladimir R Muzykantov; N N Ivanov; Vladimir P Torchilin
Evaluation of quantitative parameters of the interaction of antibody-bearing liposomes with target antigens.
Analytical biochemistry 1985;150(2):251-7.
1985: Vladimir P Torchilin; A L Klibanov; N N Ivanov; M A Gluckhova; V E Koteliansky; H K Kleinman; G R Martin
Binding of antibodies in liposomes to extracellular matrix antigens.
Journal of cellular biochemistry 1985;28(1):23-9.