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Gérard Torpier

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Christophe Zawadzki; Nicolas Chatelain; Marianne Delestre; Sophie Susen; Bruno Quesnel; Francis Juthier; Emmanuelle Jeanpierre; Richard Azzaoui; Delphine Corseaux; Joke Breyne; Gérard Torpier; Bart Staels; Eric Van Belle; Brigitte Jude
Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques.
Christophe Zawadzki; Sophie Susen; Florence Richard; Stéphan Haulon; Delphine Corseaux; Emmanuelle Jeanpierre; André Vincentelli; Christian Lucas; Gérard Torpier; Annie Martin; Eric Van Belle; Bart Staels; Brigitte Jude
Dyslipidemia shifts the tissue factor/tissue factor pathway inhibitor balance toward increased thrombogenicity in atherosclerotic plaques: evidence for a corrective effect of statins.
MARI CARMEN CARMONA; Katie Louche; Bruno Lefebvre; Antoine Pilon; Nathalie Hennuyer; Valérie Audinot-Bouchez; Catherine Fievet; Gérard Torpier; Pierre Formstecher; Pierre Renard; Philippe Lefebvre; Catherine Dacquet; Bart Staels; Louis Casteilla; Luc Pénicaud
S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.

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All Publications

2009: Christophe Zawadzki; Nicolas Chatelain; Marianne Delestre; Sophie Susen; Bruno Quesnel; Francis Juthier; Emmanuelle Jeanpierre; Richard Azzaoui; Delphine Corseaux; Joke Breyne; Gérard Torpier; Bart Staels; Eric Van Belle; Brigitte Jude
Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques.
Atherosclerosis 2009;204(2):e4-14.
2007: Christophe Zawadzki; Sophie Susen; Florence Richard; Stéphan Haulon; Delphine Corseaux; Emmanuelle Jeanpierre; André Vincentelli; Christian Lucas; Gérard Torpier; Annie Martin; Eric Van Belle; Bart Staels; Brigitte Jude
Dyslipidemia shifts the tissue factor/tissue factor pathway inhibitor balance toward increased thrombogenicity in atherosclerotic plaques: evidence for a corrective effect of statins.
Atherosclerosis 2007;195(2):e117-25.
2007: MARI CARMEN CARMONA; Katie Louche; Bruno Lefebvre; Antoine Pilon; Nathalie Hennuyer; Valérie Audinot-Bouchez; Catherine Fievet; Gérard Torpier; Pierre Formstecher; Pierre Renard; Philippe Lefebvre; Catherine Dacquet; Bart Staels; Louis Casteilla; Luc Pénicaud
S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.
Diabetes 2007;56(11):2797-808.
2007: Mohamed Amine Bouhlel; Bruno Derudas; Elena Rigamonti; Rébecca Dièvart; John Brozek; Stéphan Haulon; Christophe Zawadzki; Brigitte Jude; Gérard Torpier; Nikolaus Marx; Bart Staels; Giulia Chinetti-Gbaguidi
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties.
Cell metabolism 2007;6(2):137-43.
2007: François Brigadeau; Patrick Gelé; Maud Wibaux; Christelle Marquié; Françoise Martin-Nizard; Gérard Torpier; Jean-Charles Fruchart; Bart Staels; Patrick Duriez; Dominique Lacroix
The PPARalpha activator fenofibrate slows down the progression of the left ventricular dysfunction in porcine tachycardia-induced cardiomyopathy.
Journal of cardiovascular pharmacology 2007;49(6):408-15.
2006: Fanny Lalloyer; Catherine Fiévet; Sophie Lestavel; Gérard Torpier; Jelske van der Veen; Véronique Touche; Stéphanie Bultel; Saïd Yous; Folkert Kuipers; Réjane Paumelle; Jean-Charles Fruchart; Bart Staels; Anne Tailleux
The RXR agonist bexarotene improves cholesterol homeostasis and inhibits atherosclerosis progression in a mouse model of mixed dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(12):2731-7.
2006: Florence Gizard; Romain Robillard; Barbara Gross; Olivier Barbier; Françoise Révillion; Jean-Philippe Peyrat; Gérard Torpier; Dean W Hum; Bart Staels
TReP-132 is a novel progesterone receptor coactivator required for the inhibition of breast cancer cell growth and enhancement of differentiation by progesterone.
Molecular and cellular biology 2006;26(20):7632-44.
2006: Fanny Lalloyer; Brigitte Vandewalle; Frédéric Percevault; Gérard Torpier; Julie Kerr Conte; Maaike Oosterveer; Réjane Paumelle; Jean-Charles Fruchart; Folkert Kuipers; François Pattou; Catherine Fiévet; Bart Staels
Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
Diabetes 2006;55(6):1605-13.
2006: Hafid Mezdour; Guilhem Larigauderie; Graciela Castro; Gérard Torpier; Jamila Fruchart; Maxime NOWAK; Jean-Charles Fruchart; Mustapha Rouis; Nobuyo Maeda
Characterization of a new mouse model for human apolipoprotein A-I/C-III/A-IV deficiency.
Journal of lipid research 2006;47(5):912-20.
2006: Bertrand Cariou; Kirsten van Harmelen; Daniel Duran-Sandoval; Theo H Van Dijk; Aldo Grefhorst; Mouaadh Abdelkarim; Sandrine Caron; Gérard Torpier; Jean-Charles Fruchart; Frank J Gonzalez; Folkert Kuipers; Bart Staels
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
The Journal of biological chemistry 2006;281(16):11039-49.
2005: Florence Gizard; Carole Amant; Olivier Barbier; Stefano Bellosta; Romain Robillard; Frédéric Percevault; Henry Sevestre; Paul Krimpenfort; Alberto Corsini; Jacques Rochette; Corine Glineur; Jean-Charles Fruchart; Gérard Torpier; Bart Staels
PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a.
The Journal of clinical investigation 2005;115(11):3228-38.
2005: Anne Tailleux; Andrea Gozzo; Gérard Torpier; Françoise Martin-Nizard; Dominique Bonnefont-Rousselot; Mohamed Lemdani; Christophe Furman; Rachel Foricher; Gwénaël Chevé; Saïd Yous; Florence Micard; Régis Bordet; Monique Gardes-Albert; Daniel Lesieur; Elisabeth Teissier; Jean-Charles Fruchart; Catherine Fiévet; Patrick Duriez
Increased susceptibility of low-density lipoprotein to ex vivo oxidation in mice transgenic for human apolipoprotein B treated with 1 melatonin-related compound is not associated with atherosclerosis progression.
Journal of cardiovascular pharmacology 2005;46(3):241-9.
2005: Nathalie Hennuyer; Anne Tailleux; Gérard Torpier; Hafid Mezdour; Jean-Charles Fruchart; Bart Staels; Catherine Fiévet
PPARalpha, but not PPARgamma, activators decrease macrophage-laden atherosclerotic lesions in a nondiabetic mouse model of mixed dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(9):1897-902.
2004: Olivier Briand; Françoise Martin Nizard; Monique David-Dufilho; Isabelle Six; Sophie Lestavel; Annie Brunet; Jean-Charles Fruchart; Gérard Torpier; Régis Bordet; Véronique Clavey; Patrick Duriez
Human free apolipoprotein A-I and artificial pre-beta-high-density lipoprotein inhibit eNOS activity and NO release.
Biochimica et biophysica acta 2004;1683(1-3):69-77.
2003: Anne Tailleux; Gérard Torpier; Hafid Mezdour; Jean-Charles Fruchart; Bart Staels; Catherine Fiévet
Murine models to investigate pharmacological compounds acting as ligands of PPARs in dyslipidemia and atherosclerosis.
Trends in pharmacological sciences 2003;24(10):530-4.
2003: Laurence Descamps; Caroline Coisne; Bénédicte Dehouck; Roméo Cecchelli; Gérard Torpier
Protective effect of glial cells against lipopolysaccharide-mediated blood-brain barrier injury.
Glia 2003;42(1):46-58.
2003: Olivier Briand; Sophie Lestavel; Antoine Pilon; Gérard Torpier; Jean-Charles Fruchart; Véronique Clavey
SR-BI does not require raft/caveola localisation for cholesteryl ester selective uptake in the human adrenal cell line NCI-H295R.
Biochimica et biophysica acta 2003;1631(1):42-50.
2002: Hélène Duez; Yu-Sheng Chao; Melba Hernandez; Gérard Torpier; Philippe Poulain; Steven S Mundt; Ziad Mallat; Elisabeth Teissier; Charlotte A Burton; Alain Tedgui; Jean-Charles Fruchart; Catherine Fiévet; Samuel D Wright; Bart Staels
Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice.
The Journal of biological chemistry 2002;277(50):48051-7.
2002: Anne Tailleux; Gérard Torpier; Dominique Bonnefont-Rousselot; Sophie Lestavel; Mohamed Lemdani; Bernadette Caudeville; Christophe Furman; Rachel Foricher; Monique Gardes-Albert; Daniel Lesieur; Christian Rolando; Elisabeth Teissier; Jean-Charles Fruchart; Véronique Clavey; Catherine Fievet; Patrick Duriez
Daily melatonin supplementation in mice increases atherosclerosis in proximal aorta.
Biochemical and biophysical research communications 2002;293(3):1114-23.
2001: T Claudel; Mark D Leibowitz; Catherine Fiévet; Anne Tailleux; B Wagner; Joyce J Repa; Gérard Torpier; Jean-Marc Lobaccaro; James R Paterniti; D J Mangelsdorf; Richard A Heyman; Johan Auwerx
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2610-5.
2001: Didier Junquero; Antoine Pilon; Elisabeth Carilla-Durand; Jean-François Patoiseau; Jean-Pierre Tarayre; Gérard Torpier; Bart Staels; Jean-Charles Fruchart; Francis C Colpaert; Véronique Clavey; André Delhon
Lack of toxic effects of F 12511, a novel potent inhibitor of acyl-coenzyme A: cholesterol O-acyltransferase, on human adrenocortical cells in culture.
Biochemical pharmacology 2001;61(4):387-98.
1997: S Nion; Olivier Briand; Sophie Lestavel; Gérard Torpier; F Nazih; C Delbart; Jean-Charles Fruchart; Véronique Clavey
High-density-lipoprotein subfraction 3 interaction with glycosylphosphatidylinositol-anchored proteins.
The Biochemical journal 1997;328 ( Pt 2)():415-23.
1997: Bénédicte Dehouck; Laurence Fenart; Marie-Pierre Dehouck; A Pierce; Gérard Torpier; R Cecchelli
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier.
The Journal of cell biology 1997;138(4):877-89.
1997: Marie-Pierre Dehouck; Paul Vigne; Gérard Torpier; Jean-Philippe Breittmayer; Roméo Cecchelli; Christian Frelin
Endothelin-1 as a mediator of endothelial cell-pericyte interactions in bovine brain capillaries.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(4):464-9.
1997: Laurence Descamps; Roméo Cecchelli; Gérard Torpier
Effects of tumor necrosis factor on receptor-mediated endocytosis and barrier functions of bovine brain capillary endothelial cell monolayers.
Journal of neuroimmunology 1997;74(1-2):173-84.
1996: Laurence Descamps; Marie-Pierre Dehouck; Gérard Torpier; Roméo Cecchelli
Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells.
The American journal of physiology 1996;270(4 Pt 2):H1149-58.