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Vincenzo Tortorella

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Alessia Catalano; Alessia Carocci; Filomena Corbo; Carlo Franchini; Marilena Muraglia; Antonio Scilimati; Michela De Bellis; Annamaria De Luca; Diana Conte Camerino; Maria Stefania Sinicropi; Vincenzo Tortorella
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents.
Claudia Lamanna; Alessia Catalano; Alessia Carocci; Antonia Di Mola; Carlo Franchini; Vincenzo Tortorella; Patrick M L Vanderheyden; Maria S Sinicropi; Kimberly A Watson; Simone Sciabola
AT1 receptor ligands: virtual-screening-based design with TOPP descriptors, synthesis, and biological evaluation of pyrrolidine derivatives.
Filomena Corbo; Carlo Franchini; Giovanni Lentini; Marilena Muraglia; Carla Ghelardini; Rosanna Matucci; Nicoletta Galeotti; Elisa Vivoli; Vincenzo Tortorella
Synthesis and biological evaluation of chiral alpha-aminoanilides with central antinociceptive activity.

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2008: Alessia Catalano; Alessia Carocci; Filomena Corbo; Carlo Franchini; Marilena Muraglia; Antonio Scilimati; Michela De Bellis; Annamaria De Luca; Diana Conte Camerino; Maria Stefania Sinicropi; Vincenzo Tortorella
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents.
European journal of medicinal chemistry 2008;43(11):2535-40.
2007: Claudia Lamanna; Alessia Catalano; Alessia Carocci; Antonia Di Mola; Carlo Franchini; Vincenzo Tortorella; Patrick M L Vanderheyden; Maria S Sinicropi; Kimberly A Watson; Simone Sciabola
AT1 receptor ligands: virtual-screening-based design with TOPP descriptors, synthesis, and biological evaluation of pyrrolidine derivatives.
ChemMedChem 2007;2(9):1298-310.
2007: Filomena Corbo; Carlo Franchini; Giovanni Lentini; Marilena Muraglia; Carla Ghelardini; Rosanna Matucci; Nicoletta Galeotti; Elisa Vivoli; Vincenzo Tortorella
Synthesis and biological evaluation of chiral alpha-aminoanilides with central antinociceptive activity.
Journal of medicinal chemistry 2007;50(8):1907-15.
2006: jean-francois rolland; Domenico Tricarico; Antonio Laghezza; Fulvio Loiodice; Vincenzo Tortorella; Diana Conte Camerino
A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo.
British journal of pharmacology 2006;149(7):870-9.
2006: Michela De Bellis; Annamaria De Luca; F Rana; Maria M Cavalluzzi; Alessia Catalano; Giovanni Lentini; Carlo Franchini; Vincenzo Tortorella; Diana Conte Camerino
Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents.
British journal of pharmacology 2006;149(3):300-10.
2006: Claudio Bruno; Alessia Carocci; Alessia Catalano; Maria M Cavalluzzi; Filomena Corbo; Carlo Franchini; Giovanni Lentini; Vincenzo Tortorella
Facile, alternative route to lubeluzole, its enantiomer, and the racemate.
Chirality 2006;18(4):227-31.
2006: Antonella Liantonio; Alessandra Picollo; Elena Babini; Giuseppe Carbonara; Giuseppe Fracchiolla; Fulvio Loiodice; Vincenzo Tortorella; Michael Pusch; Diana Conte Camerino
Activation and inhibition of kidney CLC-K chloride channels by fenamates.
Molecular pharmacology 2006;69(1):165-73.
2005: Nicola A Colabufo; Francesco Berardi; Marialessandra Contino; Ferruccio Fazio; Mario Matarrese; Rosa Maria Moresco; Mauro Niso; Roberto Perrone; Vincenzo Tortorella
Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.
The Journal of pharmacy and pharmacology 2005;57(11):1453-9.
2005: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Enza Lacivita; Carmela Larizza; Marcello Leopoldo; Vincenzo Tortorella
Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.
The Journal of pharmacy and pharmacology 2005;57(10):1319-27.
2005: Arnaldo Pinelli; Cristina Godio; Antonio Laghezza; Nico Mitro; Giuseppe Fracchiolla; Vincenzo Tortorella; Antonio Lavecchia; Ettore Novellino; Jean-Charles Fruchart; Bart Staels; Maurizio Crestani; Fulvio Loiodice
Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.
Journal of medicinal chemistry 2005;48(17):5509-19.
2005: Maria Grazia Perrone; Ernesto Santandrea; Natalina Dell'Uomo; Fabio Giannessi; Ferdinando Maria Milazzo; Anna Floriana Sciarroni; Antonio Scilimati; Vincenzo Tortorella
Synthesis and biological evaluation of new clofibrate analogues as potential PPARalpha agonists.
European journal of medicinal chemistry 2005;40(2):143-54.
2004: Marcello Leopoldo; Francesco Berardi; Nicola A Colabufo; Marialessandra Contino; Enza Lacivita; Mauro Niso; Roberto Perrone; Vincenzo Tortorella
Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
Journal of medicinal chemistry 2004;47(26):6616-24.
2004: Nicola A Colabufo; Francesco Berardi; Marialessandra Contino; Mauro Niso; Carmen Abate; Roberto Perrone; Vincenzo Tortorella
Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(2):106-13.
2004: Annamaria De Luca; Sabata Pierno; Antonella Liantonio; Jean-François Desaphy; Fedele Natuzzi; Maria Paola Didonna; Ermanno Ferrannini; Harald Jockusch; Carlo Franchini; Giovanni Lentini; Filomena Corbo; Vincenzo Tortorella; Diana Conte Camerino
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse.
Neuromuscular disorders : NMD 2004;14(7):405-16.
2004: Francesco Berardi; Savina Ferorelli; Carmen Abate; Nicola A Colabufo; Marialessandra Contino; Roberto Perrone; Vincenzo Tortorella
4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity.
Journal of medicinal chemistry 2004;47(9):2308-17.
2004: Marcello Leopoldo; Francesco Berardi; Nicola A Colabufo; Marialessandra Contino; Enza Lacivita; Roberto Perrone; Vincenzo Tortorella
Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.
The Journal of pharmacy and pharmacology 2004;56(2):247-55.
2004: Alessia Catalano; Alessia Carocci; Giuseppe Fracchiolla; Carlo Franchini; Giovanni Lentini; Vincenzo Tortorella; Annamaria De Luca; Michela De Bellis; Jean-François Desaphy; Diana Conte Camerino
Stereospecific synthesis of "para-hydroxymexiletine" and sodium channel blocking activity evaluation.
Chirality 2004;16(2):72-8.
2003: Annamaria De Luca; Sophie Talon; Michela De Bellis; Jean-François Desaphy; Giovanni Lentini; Filomena Corbo; Antonio Scilimati; Carlo Franchini; Vincenzo Tortorella; Diana Conte Camerino
Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds.
Molecular pharmacology 2003;64(4):932-45.
2003: Nicola A Colabufo; Francesco Berardi; Marialessandra Contino; Roberto Perrone; Vincenzo Tortorella
A new method for evaluating sigma(2) ligand activity in the isolated guinea-pig bladder.
Naunyn-Schmiedeberg's archives of pharmacology 2003;368(2):106-12.
2003: Francesco Berardi; Fulvio Loiodice; Giuseppe Fracchiolla; Nicola A Colabufo; Roberto Perrone; Vincenzo Tortorella
Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites.
Journal of medicinal chemistry 2003;46(11):2117-24.
2003: Annamaria De Luca; Sophie Talon; Michela De Bellis; Jean-François Desaphy; Carlo Franchini; Giovanni Lentini; Alessia Catalano; Filomena Corbo; Vincenzo Tortorella; Diana Conte Camerino
Inhibition of skeletal muscle sodium currents by mexiletine analogues: specific hydrophobic interactions rather than lipophilia per se account for drug therapeutic profile.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(3):318-27.
2003: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Enza Lacivita; Marcello Leopoldo; Vincenzo Tortorella
Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.
Journal of medicinal chemistry 2003;46(4):646-9.
2002: Marcello Leopoldo; Francesco Berardi; Nicola A Colabufo; Paola De Giorgio; Enza Lacivita; Roberto Perrone; Vincenzo Tortorella
Structure-affinity relationship study on N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamides as potent and selective dopamine D(3) receptor ligands.
Journal of medicinal chemistry 2002;45(26):5727-35.
2001: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Marcello Leopoldo; Enza Lacivita; Vincenzo Tortorella; A Leonardi; E Poggesi; R Testa
trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
Journal of medicinal chemistry 2001;44(25):4431-42.
2001: Nicola A Colabufo; Francesco Berardi; R Calò; Marcello Leopoldo; Roberto Perrone; Vincenzo Tortorella
Determination of dopamine D(4) receptor density in rat striatum using PB12 as a probe.
European journal of pharmacology 2001;427(1):1-5.
2001: Francesco Berardi; Savina Ferorelli; Nicola A Colabufo; Marcello Leopoldo; Roberto Perrone; Vincenzo Tortorella
A multireceptorial binding reinvestigation on an extended class of sigma ligands: N-[omega-(indan-1-yl and tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine reveal high affinities towards sigma1 and EBP sites.
Bioorganic & medicinal chemistry 2001;9(5):1325-35.
2001: Savina Ferorelli; Fulvio Loiodice; Vincenzo Tortorella; Diana Conte Camerino; Annamaria De Luca
Carboxylic acids and skeletal muscle chloride channel conductance: effects on the biological activity induced by the introduction of methyl groups on the aromatic ring of chiral alpha-(4-chloro-phenoxy)alkanoic acids.
Farmaco (Società chimica italiana : 1989) 2001;56(3):239-46.
2000: Savina Ferorelli; Fulvio Loiodice; A Longo; A Molfetta; Vincenzo Tortorella; Rosa Amoroso
Different behavior toward racemization in basic media from chiral analogs of clofibric acid, the active metabolite of the antilipidemic drug clofibrate.
Chirality 2000;12(10):697-704.
2000: Carlo Franchini; Filomena Corbo; Giovanni Lentini; G Bruno; Antonio Scilimati; Vincenzo Tortorella; Diana Conte Camerino; Annamaria De Luca
Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na(+) channels with increased potency and improved use-dependent activity.
Journal of medicinal chemistry 2000;43(20):3792-8.
2000: Michael Pusch; Antonella Liantonio; L Bertorello; Alessio Accardi; Annamaria De Luca; Sabata Pierno; Vincenzo Tortorella; Diana Conte Camerino
Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives.
Molecular pharmacology 2000;58(3):498-507.
2000: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Marcello Leopoldo; Vincenzo Tortorella
1-Substituted-4-[3-(1,2,3,4-tetrahydro-5- or 7-methoxynaphthalen-1-yl)propyl]piperazines: influence of the N-1 piperazine substituent on 5-HT1A receptor affinity and selectivity versus D2 and alpha1 receptors. Part 6.
Bioorganic & medicinal chemistry 2000;8(5):873-81.
2000: Alessia Carocci; Carlo Franchini; Giovanni Lentini; Fulvio Loiodice; Vincenzo Tortorella
Facile entry to (-)-(R)- and (+)-(S)-mexiletine.
Chirality 2000;12(3):103-6.
2000: Annamaria De Luca; Fedele Natuzzi; Jean-François Desaphy; G Loni; Giovanni Lentini; Carlo Franchini; Vincenzo Tortorella; Diana Conte Camerino
Molecular determinants of mexiletine structure for potent and use-dependent block of skeletal muscle sodium channels.
Molecular pharmacology 2000;57(2):268-77.
2000: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Marcello Leopoldo; Vincenzo Tortorella
A structure-affinity relationship study on derivatives of N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a high-affinity and selective D(4) receptor ligand.
Journal of medicinal chemistry 2000;43(2):270-7.
2000: Andrea Duranti; Carlo Franchini; Giovanni Lentini; Fulvio Loiodice; Vincenzo Tortorella; A De Luca; Sabata Pierno; Diana Conte Camerino
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels.
European journal of medicinal chemistry 2000;35(1):147-56.
1999: Jean-François Desaphy; Diana Conte Camerino; Carlo Franchini; Giovanni Lentini; Vincenzo Tortorella; Annamaria De Luca
Increased hindrance on the chiral carbon atom of mexiletine enhances the block of rat skeletal muscle Na+ channels in a model of myotonia induced by ATX.
British journal of pharmacology 1999;128(6):1165-74.
1999: Jean-François Desaphy; Diana Conte Camerino; Vincenzo Tortorella; Annamaria De Luca
Effect of mexiletine on sea anemone toxin-induced non-inactivating sodium channels of rat skeletal muscle: a model of sodium channel myotonia.
Neuromuscular disorders : NMD 1999;9(3):182-9.
1999: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Marcello Leopoldo; Vincenzo Tortorella
1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Journal of medicinal chemistry 1999;42(3):490-6.
1998: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Marcello Leopoldo; Vincenzo Tortorella
N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide: a potent and selective dopamine D4 ligand.
Journal of medicinal chemistry 1998;41(24):4903-9.
1998: Francesco Berardi; S Santoro; Roberto Perrone; Vincenzo Tortorella; Stefano Govoni; Laura Lucchi
N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands.
Journal of medicinal chemistry 1998;41(21):3940-7.
1998: Domenico Tricarico; Mariagrazia Barbieri; Carlo Franchini; Vincenzo Tortorella; Diana Conte Camerino
Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action.
British journal of pharmacology 1998;125(4):858-64.
1997: Annamaria De Luca; Fedele Natuzzi; G Falcone; Andrea Duranti; Giovanni Lentini; Carlo Franchini; Vincenzo Tortorella; Diana Conte Camerino
Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide.
Naunyn-Schmiedeberg's archives of pharmacology 1997;356(6):777-87.
1997: Annamaria De Luca; Sabata Pierno; Fedele Natuzzi; Carlo Franchini; Andrea Duranti; Giovanni Lentini; Vincenzo Tortorella; Harald Jockusch; Diana Conte Camerino
Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse.
The Journal of pharmacology and experimental therapeutics 1997;282(1):93-100.
1997: Savina Ferorelli; Fulvio Loiodice; Vincenzo Tortorella; Rosa Amoroso; Giancarlo Bettoni; Diana Conte Camerino; Annamaria De Luca
Isosteres of chiral clofibric acid analogs: synthesis, resolution, absolute configuration and HPLC detection of the optical purity.
Farmaco (Società chimica italiana : 1989) 1997;52(6-7):367-74.
1997: SM Rangwala; Michelle L O'Brien; Vincenzo Tortorella; A Longo; Fulvio Loiodice; Daniel J Noonan; Dennis R Feller
Stereoselective effects of chiral clofibric acid analogs on rat peroxisome proliferator-activated receptor alpha (rPPAR alpha) activation and peroxisomal fatty acid beta-oxidation.
Chirality 1997;9(1):37-47.
1996: Dennis R Feller; M O'Brien; S M Rangwala; Vincenzo Tortorella; Fulvio Loiodice; Daniel J Noonan
Structural requirements of chiral clofibric acid analogs for activation of the rat peroxisome proliferator-activated receptor alpha.
Annals of the New York Academy of Sciences 1996;804():713-5.
1996: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Marcello Leopoldo; Vincenzo Tortorella; Maria Gioia Fornaretto; Carla Caccia; Robert McArthur
Structure-activity relationship studies on the 5-HT(1A) receptor affinity of 1-phenyl-4-[omega-(alpha- or beta-tetralinyl)alkyl]piperazines. 4.
Journal of medicinal chemistry 1996;39(25):4928-34.
1996: Francesco Berardi; G Giudice; Roberto Perrone; Vincenzo Tortorella; Stefano Govoni; L Lucchi
Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
Journal of medicinal chemistry 1996;39(21):4255-60.
1996: Roberto Perrone; Francesco Berardi; Marcello Leopoldo; Vincenzo Tortorella; Maria Gioia Fornaretto; Carla Caccia; Robert McArthur
1-aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3.
Journal of medicinal chemistry 1996;39(16):3195-202.
1996: K J Romstedt; Longping Lei; Dennis R Feller; D T Witiak; Fulvio Loiodice; Vincenzo Tortorella
Differential eudismic ratios in the antagonism of human platelet function by phenoxy- and thiophenoxyacetic acids.
Farmaco (Società chimica italiana : 1989) 1996;51(2):107-14.
1996: Francesco Berardi; Nicola A Colabufo; G Giudice; Roberto Perrone; Vincenzo Tortorella; Stefano Govoni; L Lucchi
New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Journal of medicinal chemistry 1996;39(1):176-82.
1995: Annamaria De Luca; Fedele Natuzzi; Giovanni Lentini; Carlo Franchini; Vincenzo Tortorella; Diana Conte Camerino
Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(6):653-61.
1995: Roberto Perrone; Francesco Berardi; Marcello Leopoldo; Vincenzo Tortorella; Marcello D Lograno; E Daniele; Stefano Govoni
5-HT1A and D-2 receptor affinity of o-methoxyphenylpiperazine derivatives with terminal benzamide fragment on N-4 alkyl chain. 2.
Farmaco (Società chimica italiana : 1989) 1995;50(7-8):505-10.
1995: Angelo Carotti; Cosimo Altomare; Saverio Cellamare; Anna Maria Monforte; G Bettoni; Fulvio Loiodice; N Tangari; Vincenzo Tortorella
LFER and CoMFA studies on optical resolution of alpha-alkyl alpha-aryloxy acetic acid methyl esters on DACH-DNB chiral stationary phase.
Journal of computer-aided molecular design 1995;9(2):131-8.
1995: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Marcello Leopoldo; Vincenzo Tortorella; F Fiorentini; V Olgiati; A Ghiglieri; Stefano Govoni
High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[1-tetralin)alkyl]piperazines. 2.
Journal of medicinal chemistry 1995;38(6):942-9.
1994: Roberto Perrone; Francesco Berardi; Marcello Leopoldo; Vincenzo Tortorella; Marcello D Lograno; E Daniele; Stefano Govoni
5-HT and DA receptor affinity of arylpiperazine derivatives with terminal benzamide fragment.
Farmaco (Società chimica italiana : 1989) 1994;49(9):567-72.
1994: Roberto Perrone; Francesco Berardi; Nicola A Colabufo; Vincenzo Tortorella; F Fiorentini; V Olgiati; E Vanotti; Stefano Govoni
Mixed 5-HT1A/D-2 activity of a new model of arylpiperazines: 1-aryl-4-[3-(1,2-dihydronaphthalen-4-yl)-n-propyl]piperazines. 1. Synthesis and structure-activity relationships.
Journal of medicinal chemistry 1994;37(1):99-104.
1993: Fulvio Loiodice; S Ferorelli; N Tangari; G Bettoni; Vincenzo Tortorella; Sabata Pierno; Annamaria De Luca; Domenico Tricarico; Diana Conte Camerino
Carboxylic acids and chloride conductance in skeletal muscle: influence on the pharmacological activity induced by the chain substituents and the distance between the phenolic group and the carboxylic function in 4-chloro-phenoxy alkanoic acids.
Farmaco (Società chimica italiana : 1989) 1993;48(1):45-63.
1993: Carlo Franchini; F C Noja; F Corbo; Giovanni Lentini; Vincenzo Tortorella; Alessandro Bartolini; Carla Ghelardini; Rosanna Matucci; A Giotti
Stereoselectivity in central analgesic action of tocainide and its analogs.
Chirality 1993;5(3):135-42.
1992: Annamaria De Luca; Vincenzo Tortorella; Diana Conte Camerino
Chloride channels of skeletal muscle from developing, adult and aged rats are differently affected by enantiomers of 2-(p-chlorophenoxy) propionic acid.
Naunyn-Schmiedeberg's archives of pharmacology 1992;346(6):601-6.
1992: Roberto Perrone; Francesco Berardi; S Ferorelli; Vincenzo Tortorella; Marcello D Lograno; E Daniele; Stefano Govoni
8-Methoxy- and p-dimethoxy-1-aminoethylhetero-tetralins: synthesis and DA, 5-HT receptors affinities.
Farmaco (Società chimica italiana : 1989) 1992;47(10):1285-91.
1992: Roberto Perrone; Francesco Berardi; Marcello Leopoldo; Vincenzo Tortorella; Marcello D Lograno; E Daniele; Stefano Govoni
Oxygen isosteric derivatives of 3-(3-hydroxyphenyl)-N-n-propylpiperidine.
Journal of medicinal chemistry 1992;35(16):3045-9.
1992: Annamaria De Luca; Domenico Tricarico; R Wagner; S H Bryant; Vincenzo Tortorella; Diana Conte Camerino
Opposite effects of enantiomers of clofibric acid derivative on rat skeletal muscle chloride conductance: antagonism studies and theoretical modeling of two different receptor site interactions.
The Journal of pharmacology and experimental therapeutics 1992;260(1):364-8.
1991: Domenico Tricarico; Bernd Fakler; W Spittelmeister; J Peter Ruppersberg; R Stützel; Carlo Franchini; Vincenzo Tortorella; Diana Conte Camerino; Reinhardt Rüdel
Stereoselective interaction of tocainide and its chiral analogs with the sodium channels in human myoballs.
Pflügers Archiv : European journal of physiology 1991;418(3):234-7.
1990: T A Esbenshade; V S Kamanna; H A Newman; Vincenzo Tortorella; D T Witiak; Dennis R Feller
In vivo and in vitro peroxisome proliferation properties of selected clofibrate analogues in the rat. Structure-activity relationships.
Biochemical pharmacology 1990;40(6):1263-74.
1990: Domenico Tricarico; Carlo Franchini; Giovanni Lentini; Diana Conte Camerino; Vincenzo Tortorella; Reinhardt Rüdel
The effects of tocainide and its chiral analogs on sodium channels of human muscle.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22 Suppl 1():95-6.
1990: Roberto Perrone; Francesco Berardi; Vincenzo Tortorella; G Racagni; A Rovescalli
Dopaminergic activity and stereochemical considerations for rigid angular tricyclic congeners of dopamine: benzoquinoxalines and naphthothiazines.
Farmaco (Società chimica italiana : 1989) 1990;45(5):479-88.
1990: Judith A Heiny; D Jong; S H Bryant; Diana Conte Camerino; Vincenzo Tortorella
Enantiomeric effects on excitation-contraction coupling in frog skeletal muscle by a chiral phenoxy carboxylic acid.
Biophysical journal 1990;57(1):147-52.
1989: Diana Conte Camerino; Domenico Tricarico; Carlo Franchini; Vincenzo Tortorella
Stereospecific effects of tocainide and its chiral derivatives on rat skeletal muscle sodium channel.
Pharmacological research : the official journal of the Italian Pharmacological Society 1989;21 Suppl 1():7-8.
1988: Diana Conte Camerino; Vincenzo Tortorella; G Bettoni; S H Bryant; Annamaria De Luca; M Mambrini; Domenico Tricarico; G Grasso
A stereospecific binding site regulates the C1- ion channel in rat skeletal muscle.
Pharmacological research communications 1988;20(12):1077-8.
1988: Diana Conte Camerino; M Mambrini; A DeLuca; Domenico Tricarico; S H Bryant; Vincenzo Tortorella; G Bettoni
Enantiomers of clofibric acid analogs have opposite actions on rat skeletal muscle chloride channels.
Pflügers Archiv : European journal of physiology 1988;413(1):105-7.
1988: Roberto Perrone; Francesco Berardi; G Bettoni; Vincenzo Tortorella
Synthesis of new linearly annulated tricycles as rigid dopamine congeners.
Il Farmaco; edizione scientifica 1988;43(1):71-7.
1988: Roberto Perrone; Francesco Berardi; G Bettoni; Vincenzo Tortorella
Dopamine receptor agonists: new angularly annulated tricyclic compounds.
Il Farmaco; edizione scientifica 1988;43(1):61-9.
1987: G Bettoni; Fulvio Loiodice; Vincenzo Tortorella; Diana Conte Camerino; M Mambrini; E Ferrannini; S H Bryant
Stereospecificity of the chloride ion channel: the action of chiral clofibric acid analogues.
Journal of medicinal chemistry 1987;30(8):1267-70.
1987: Dennis R Feller; V S Kamanna; H A Newman; K J Romstedt; D T Witiak; G Bettoni; S H Bryant; Diana Conte Camerino; Fulvio Loiodice; Vincenzo Tortorella
Dissociation of hypolipidemic and antiplatelet actions from adverse myotonic effects of clofibric acid related enantiomers.
Journal of medicinal chemistry 1987;30(8):1265-7.
1984: Diana Conte Camerino; Vincenzo Tortorella; E Ferranini; S H Bryant
The toxic effects of clofibrate and its metabolite on mammalian skeletal muscle: an electrophysiological study.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1984;7():482-4.