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Attila Toth

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Wei Sun; Shivaji A Thorat; Attila Toth; Richard Tran; Keliang Liu; Matthew A Morgan; Vladimir A Pavlyukovets; Larry V Pearce; Christopher B Ryder; Hyungchul Ryu; Rahul S Bhondwe; Peter M Blumberg; Yongsung Cho; Dong Wook Kang; Ho Shin Kim; Myeong Seop Kim; Yong Soo Kim; Jozsef Lazar; Jeewoo Lee
2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure-activity relationships in the B and C-regions.
Hyun-Kyung Choi; Sun Choi; Yoonji Lee; Dong Wook Kang; Hyungchul Ryu; Han-Joo Maeng; Suk-Jae Chung; Vladimir A Pavlyukovets; Larry V Pearce; Attila Toth; Richard Tran; Yun Wang; Matthew A Morgan; Peter M Blumberg; Jeewoo Lee
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Ju-Ok Lim; Mi-Kyoung Jin; Hyungchul Ryu; Dong Wook Kang; Jeewoo Lee; Larry V Pearce; Richard Tran; Attila Toth; Peter M Blumberg
Conformationally constrained analogues of N'-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl)thiourea as TRPV1 antagonists.

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All Publications

2012: Wei Sun; Shivaji A Thorat; Attila Toth; Richard Tran; Keliang Liu; Matthew A Morgan; Vladimir A Pavlyukovets; Larry V Pearce; Christopher B Ryder; Hyungchul Ryu; Rahul S Bhondwe; Peter M Blumberg; Yongsung Cho; Dong Wook Kang; Ho Shin Kim; Myeong Seop Kim; Yong Soo Kim; Jozsef Lazar; Jeewoo Lee
2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure-activity relationships in the B and C-regions.
Bioorganic & medicinal chemistry 2012;20(3):1310-8.
2009: Hyun-Kyung Choi; Sun Choi; Yoonji Lee; Dong Wook Kang; Hyungchul Ryu; Han-Joo Maeng; Suk-Jae Chung; Vladimir A Pavlyukovets; Larry V Pearce; Attila Toth; Richard Tran; Yun Wang; Matthew A Morgan; Peter M Blumberg; Jeewoo Lee
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Bioorganic & medicinal chemistry 2009;17(2):690-8.
2009: Ju-Ok Lim; Mi-Kyoung Jin; Hyungchul Ryu; Dong Wook Kang; Jeewoo Lee; Larry V Pearce; Richard Tran; Attila Toth; Peter M Blumberg
Conformationally constrained analogues of N'-(4-tert-butylbenzyl)-N-(4-methylsulfonylaminobenzyl)thiourea as TRPV1 antagonists.
European journal of medicinal chemistry 2009;44(1):322-31.
2008: Larry V Pearce; Attila Toth; HyungChul Ryu; Dong Wook Kang; Hyun-Kyung Choi; Mi-Kyung Jin; Jeewoo Lee; Peter M Blumberg
Differential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitors.
Naunyn-Schmiedeberg's archives of pharmacology 2008;377(2):149-57.
2008: Hyungchul Ryu; Mi-Kyung Jin; Su Yeon Kim; Hyun-Kyung Choi; Sang-Uk Kang; Dong Wook Kang; Jeewoo Lee; Larry V Pearce; Vladimir A Pavlyukovets; Matthew A Morgan; Richard Tran; Attila Toth; Daniel J Lundberg; Peter M Blumberg
Stereospecific high-affinity TRPV1 antagonists: chiral N-(2-benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide analogues.
Journal of medicinal chemistry 2008;51(1):57-67.
2007: Jae-Uk Chung; Su Yeon Kim; Ju-Ok Lim; Hyun-Kyung Choi; Sang-Uk Kang; Hae-Seok Yoon; Hyungchul Ryu; Dong Wook Kang; Jeewoo Lee; Bomi Kang; Sun Choi; Attila Toth; Larry V Pearce; Vladimir A Pavlyukovets; Daniel J Lundberg; Peter M Blumberg
Alpha-substituted N-(4-tert-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists.
Bioorganic & medicinal chemistry 2007;15(18):6043-53.
2005: Jeewoo Lee; Sang-Uk Kang; Min-Jung Kil; Myoungyoup Shin; Ju-Ok Lim; Hyun-Kyung Choi; Mi-Kyung Jin; Su Yeon Kim; Sung-Eun Kim; Yong-Sil Lee; Kyung-Hoon Min; Young-Ho Kim; Hee-Jin Ha; Richard Tran; Jacqueline D Welter; Yun Wang; Tamas Szabo; Larry V Pearce; Daniel J Lundberg; Attila Toth; Vladimir A Pavlyukovets; Matthew A Morgan; Peter M Blumberg
Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.
Bioorganic & medicinal chemistry letters 2005;15(18):4136-42.
2005: Jeewoo Lee; Mi-Kyung Jin; Sang-Uk Kang; Su Yeon Kim; Jiyoun Lee; Myoungyoup Shin; Jaemin Hwang; Sookhyun Cho; Yeon-Sil Choi; Hyun-Kyung Choi; Sung-Eun Kim; Young-Ger Suh; Yong-Sil Lee; Young-Ho Kim; Hee-Jin Ha; Attila Toth; Larry V Pearce; Richard Tran; Tamas Szabo; Jacqueline D Welter; Daniel J Lundberg; Yun Wang; Jozsef Lazar; Vladimir A Pavlyukovets; Matthew A Morgan; Peter M Blumberg
Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.
Bioorganic & medicinal chemistry letters 2005;15(18):4143-50.
2004: Yun Wang; Noemi Kedei; Min Wang; Qiming J Wang; Anna R Huppler; Attila Toth; Richard Tran; Peter M Blumberg
Interaction between protein kinase Cmu and the vanilloid receptor type 1.
The Journal of biological chemistry 2004;279(51):53674-82.
2004: Chaya Brodie; Rivka Steinhart; Gila Kazimirsky; Hadara Rubinfeld; Tehila Hyman; Jolene N Ayres; Gang Min Hur; Attila Toth; Dazhi Yang; Susan H Garfield; James C Stone; Peter M Blumberg
PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters.
Molecular pharmacology 2004;66(1):76-84.
2004: Jeewoo Lee; Su Yeon Kim; Jiyoun Lee; Myungshim Kang; Min-Jung Kil; Hyun-Kyung Choi; Mi-Kyung Jin; Yun Wang; Attila Toth; Larry V Pearce; Daniel J Lundberg; Richard Tran; Peter M Blumberg
Analysis of structure-activity relationships with the N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea template for vanilloid receptor 1 antagonism.
Bioorganic & medicinal chemistry 2004;12(13):3411-20.
2004: Narender R Gavva; Lana Klionsky; Yusheng Qu; Licheng Shi; Rami Tamir; Steve Edenson; Tie J Zhang; Vellarkad Viswanadhan; Attila Toth; Larry V Pearce; Todd W Vanderah; Frank Porreca; Peter M Blumberg; Jack Lile; Yax Sun; Kenneth D Wild; Jean-Claude Louis; James J S Treanor
Molecular determinants of vanilloid sensitivity in TRPV1.
The Journal of biological chemistry 2004;279(19):20283-95.
2004: Jeewoo Lee; Sang-Uk Kang; Hyun-Kyung Choi; Jiyoun Lee; Ju-Ok Lim; Min-Jung Kil; Mi-Kyung Jin; Kang-Pil Kim; Jong-Hyuk Sung; Suk-Jae Chung; Hee-Jin Ha; Young-Ho Kim; Larry V Pearce; Richard Tran; Daniel J Lundberg; Yun Wang; Attila Toth; Peter M Blumberg
Analysis of structure-activity relationships for the 'B-region' of N-(3-acyloxy-2-benzylpropyl)-N(')-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N-hydroxythiourea analogue with potent analgesic activity.
Bioorganic & medicinal chemistry letters 2004;14(9):2291-7.
2004: Noemi Kedei; Daniel J Lundberg; Attila Toth; Peter Welburn; Susan H Garfield; Peter M Blumberg
Characterization of the interaction of ingenol 3-angelate with protein kinase C.
Cancer research 2004;64(9):3243-55.
2004: Jeewoo Lee; Su Yeon Kim; Soyoung Park; Ju-Ok Lim; Ji-Min Kim; Myungshim Kang; Jiyoun Lee; Sang-Uk Kang; Hyun-Kyung Choi; Mi-Kyung Jin; Jacqueline D Welter; Tamas Szabo; Richard Tran; Larry V Pearce; Attila Toth; Peter M Blumberg
Structure-activity relationships of simplified resiniferatoxin analogues with potent VR1 agonism elucidates an active conformation of RTX for VR1 binding.
Bioorganic & medicinal chemistry 2004;12(5):1055-69.
2004: Jeewoo Lee; Sang-Uk Kang; Ju-Ok Lim; Hyun-Kyung Choi; Mi-Kyung Jin; Attila Toth; Larry V Pearce; Richard Tran; Yun Wang; Tamas Szabo; Peter M Blumberg
N-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: analysis of structure-activity relationships for the "C-Region".
Bioorganic & medicinal chemistry 2004;12(2):371-85.
2003: Yun Wang; Attila Toth; Richard Tran; Tamas Szabo; Jacqueline D Welter; Peter M Blumberg; Jiyoun Lee; Sang-Uk Kang; Ju-Ok Lim; Jeewoo Lee
High-affinity partial agonists of the vanilloid receptor.
Molecular pharmacology 2003;64(2):325-33.
2003: Jeewoo Lee; Jiyoun Lee; Myungshim Kang; Myoungyoup Shin; Ji-Min Kim; Sang-Uk Kang; Ju-Ok Lim; Hyun-Kyung Choi; Young-Ger Suh; Hyeung-geun Park; Uhtaek Oh; Hee-Doo Kim; Young-Ho Park; Hee-Jin Ha; Young-Ho Kim; Attila Toth; Yun Wang; Richard Tran; Larry V Pearce; Daniel J Lundberg; Peter M Blumberg
N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.
Journal of medicinal chemistry 2003;46(14):3116-26.
2002: Yun Wang; Tamas Szabo; Jacqueline D Welter; Attila Toth; Richard Tran; Jiyoun Lee; Sang-Uk Kang; Young-Ger Suh; Peter M Blumberg; Jeewoo Lee
High affinity antagonists of the vanilloid receptor.
Molecular pharmacology 2002;62(4):947-56.