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Olivier Toussaint

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Physiology

Anatomy

Chemicals & Drugs

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Publications

TOP 3
Jean-Pascal Piret; Christelle Saout; Jean-Nicolas Audinot; Emmanuelle Boilan; Catherine Demazy; Maude Fransolet; Diane Jacques; Stéphane Lucas; Jorge Mejia; Florence Noël; Olivier Toussaint
Copper(II) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response.
Jean-Pascal Piret; Christelle Saout; Sébastien Vankoningsloo; Christos C Zouboulis; Emmanuelle Boilan; Françoise Lambinon; Stéphane Lucas; Bernard Masereel; Jorge Mejia; Florence Noël; Olivier Toussaint
Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape.
Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Florence Debacq-Chainiaux; Christian Swine; Vincent Geenen; Henri Martens; Olivier Toussaint
Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls.

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All Publications

2012: Jean-Pascal Piret; Christelle Saout; Jean-Nicolas Audinot; Emmanuelle Boilan; Catherine Demazy; Maude Fransolet; Diane Jacques; Stéphane Lucas; Jorge Mejia; Florence Noël; Olivier Toussaint
Copper(II) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response.
Nanoscale 2012;4(22):7168-84.
2012: Jean-Pascal Piret; Christelle Saout; Sébastien Vankoningsloo; Christos C Zouboulis; Emmanuelle Boilan; Françoise Lambinon; Stéphane Lucas; Bernard Masereel; Jorge Mejia; Florence Noël; Olivier Toussaint
Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape.
Nanotoxicology 2012;6(7):789-803.
2011: Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Florence Debacq-Chainiaux; Christian Swine; Vincent Geenen; Henri Martens; Olivier Toussaint
Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls.
Experimental gerontology 2011;46(4):257-64.
2011: Thi Kim Duy Vo; Marie de Saint-Hubert; Gabriel Morrhaye; Patrice Godard; Vincent Geenen; Henri Martens; Florence Debacq-Chainiaux; Christian Swine; Olivier Toussaint
Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture.
Mechanisms of ageing and development 2011;132(3):131-9.
2011: Olivier Toussaint; Geoffroy Weemaels; Florence Debacq-Chainiaux; Karin Scharffetter-Kochanek; Meinhard Wlaschek
Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology.
Journal of cellular physiology 2011;226(2):315-21.
2010: Valerie Vanhooren; Sylviane Dewaele; Claude Libert; Sebastiaan Engelborghs; Peter Paul De Deyn; Olivier Toussaint; Florence Debacq-Chainiaux; Michel Poulain; Youri Glupczynski; Claudio Franceschi; Koos Jaspers; Ingrid van der Pluijm; Jan Hoeijmakers; Cuiying Chitty Chen
Serum N-glycan profile shift during human ageing.
Experimental gerontology 2010;45(10):738-43.
2010: Véronique Bertrand-Vallery; Emmanuelle Boilan; Noëlle Ninane; Catherine Demazy; Bertrand Friguet; Olivier Toussaint; Yves Poumay; Florence Debacq-Chainiaux
Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A).
Biogerontology 2010;11(2):167-81.
2010: Johan Robbens; Caroline Vanparys; Ingrid Nobels; Ronny Blust; Karen Van Hoecke; Colin Janssen; Karel De Schamphelaere; Kathleen Roland; Gersande Blanchard; Frédéric Silvestre; Virginie Gillardin; Patrick Kestemont; Roel Anthonissen; Olivier Toussaint; Sébastien Vankoningsloo; Christelle Saout; Ernesto Alfaro-Moreno; Peter Hoet; Laetitia Gonzalez; Peter Dubruel; Paul Troisfontaines
Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications.
Toxicology 2010;269(2-3):170-81.
2010: Sebastien Vankoningsloo; Jean-Pascal Piret; Christelle Saout; Florence Noel; Jorge Mejia; Christos C Zouboulis; Joseph Delhalle; Stephane Lucas; Olivier Toussaint
Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: effects of sonication, dispersive agents and corneous layer of reconstructed epidermis.
Nanotoxicology 2010;4(1):84-97.
2010: Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Emilie Bauwens; Florence Debacq-Chainiaux; Youri Glupczynski; Christian Swine; Vincent Geenen; Henri Martens; Olivier Toussaint
Transcriptomic biomarkers of human ageing in peripheral blood mononuclear cell total RNA.
Experimental gerontology 2010;45(3):188-94.
2010: Florence Debacq-Chainiaux; Emmanuelle Boilan; Jérémie Dedessus Le Moutier; Geoffroy Weemaels; Olivier Toussaint
p38(MAPK) in the senescence of human and murine fibroblasts.
Advances in experimental medicine and biology 2010;694():126-37.
2010: Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Christian Swine; Vincent Geenen; Henri Martens; Florence Debacq-Chainiaux; Olivier Toussaint
Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases.
Immunity & ageing : I & A 2010;7():9.
2010: Véronique Bertrand-Vallery; Nathalie Belot; Marc Dieu; Edouard Delaive; Noëlle Ninane; Catherine Demazy; Martine Raes; Michel Salmon; Yves Poumay; Florence Debacq-Chainiaux; Olivier Toussaint
Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor.
PloS one 2010;5(5):e10462.
2009: Stéphanie Zdanov; Olivier Toussaint; Florence Debacq-Chainiaux
p53 and ATF-2 partly mediate the overexpression of COX-2 in H(2)O (2)-induced premature senescence of human fibroblasts.
Biogerontology 2009;10(3):291-8.
2009: Florence Debacq-Chainiaux; Jorge D Erusalimsky; Judith Campisi; Olivier Toussaint
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo.
Nature protocols 2009;4(12):1798-806.
2009: Christian Q Scheckhuber; Jürgen Grief; Emmanuelle Boilan; Karin Luce; Florence Debacq-Chainiaux; Claudia Rittmeyer; Ricardo Gredilla; BO Kolbesen; Olivier Toussaint; Heinz D Osiewacz
Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts.
PloS one 2009;4(3):e4919.
2008: Céline Borlon; Geoffroy Weemaels; Patrice Godard; Florence Debacq-Chainiaux; Pierre Lemaire; Christophe Deroanne; Olivier Toussaint
Expression profiling of senescent-associated genes in human dermis from young and old donors. Proof-of-concept study.
Biogerontology 2008;9(3):197-208.
2008: Aline Chrétien; Neil Piront; Edouard Delaive; Catherine Demazy; Noëlle Ninane; Olivier Toussaint
Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H(2)O(2)-induced premature senescence and interplay with p38alpha(MAPK).
FEBS letters 2008;582(12):1685-92.
2008: Florence Debacq-Chainiaux; Thierry Pascal; Emmanuelle Boilan; Coralie Bastin; Emilie Bauwens; Olivier Toussaint
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts.
Free radical biology & medicine 2008;44(10):1817-32.
2008: Aline Chrétien; Jean-François Dierick; Edouard Delaive; Martin Røssel Larsen; Marc Dieu; Martine Raes; Christophe F Deroanne; Peter Roepstorff; Olivier Toussaint
Role of TGF-beta1-independent changes in protein neosynthesis, p38alphaMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis.
Free radical biology & medicine 2008;44(9):1732-51.
2008: Aline Chrétien; Edouard Delaive; Marc Dieu; Catherine Demazy; Noëlle Ninane; Martine Raes; Olivier Toussaint
Upregulation of annexin A2 in H(2)O(2)-induced premature senescence as evidenced by 2D-DIGE proteome analysis.
Experimental gerontology 2008;43(4):353-9.
2008: Céline Borlon; Sébastien Vankoningsloo; Patrice Godard; Florence Debacq-Chainiaux; Olivier Toussaint
Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology.
Mechanisms of ageing and development 2008;129(3):109-19.
2008: Anne Bigot; Virginie Jacquemin; Florence Debacq-Chainiaux; Gillian Butler-Browne; Olivier Toussaint; Denis Furling; Vincent Mouly
Replicative aging down-regulates the myogenic regulatory factors in human myoblasts.
Biology of the cell / under the auspices of the European Cell Biology Organization 2008;100(3):189-99.
2007: Céline Borlon; Patrice Godard; Chantra Eskes; Thomas Hartung; Valérie Zuang; Olivier Toussaint
The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis.
Toxicology 2007;241(3):157-66.
2007: Céline Borlon; Aline Chretien; Florence Debacq-Chainiaux; Olivier Toussaint
Transient increased extracellular release of H2O2 during establishment of UVB-induced premature senescence.
Annals of the New York Academy of Sciences 2007;1119():72-7.
2007: Céline Borlon; Florence Debacq-Chainiaux; Christina Hinrichs; Karin Scharffetter-Kochanek; Olivier Toussaint; Meinhard Wlaschek
The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype.
Experimental gerontology 2007;42(9):911-23.
2007: Stéphanie Zdanov; David Bernard; Florence Debacq-Chainiaux; Sébastien Martien; Karo Gosselin; Chantal Vercamer; Fazia Chelli; Olivier Toussaint; Corinne Abbadie
Normal or stress-induced fibroblast senescence involves COX-2 activity.
Experimental cell research 2007;313(14):3046-56.
2007: Thierry Pascal; Florence Debacq-Chainiaux; Emmanuelle Boilan; Noelle Ninane; Martine Raes; Olivier Toussaint
Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol.
Biogerontology 2007;8(4):409-22.
2007: Stéphanie Zdanov; Florence Debacq-Chainiaux; Olivier Toussaint
Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence.
Annals of the New York Academy of Sciences 2007;1100():316-22.
2006: Florence Debacq-Chainiaux; Céline Borlon; B De Hertogh; José Remacle; Pierre-Yves Morvan; R Vallée; Olivier Toussaint
Identification of potential anti-photoageing algal compounds using an in-vitro model of photoageing.
The Journal of pharmacy and pharmacology 2006;58(12):1577-83.
2006: Stéphanie Zdanov; Florence Debacq-Chainiaux; José Remacle; Olivier Toussaint
Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts.
FEBS letters 2006;580(27):6455-63.
2006: Olivier Toussaint; Béatrice Rayet; Florence Chainiaux; Christos Zouboulis; Gillian Butler-Browne; Chitty Chen; Thomas B L Kirkwood
LINK-AGE: coordination and consolidation of European biogerontology: en route towards formation of a European college of biogerontology.
Mechanisms of ageing and development 2006;127(10):761-2.
2006: Stéphanie Zdanov; José Remacle; Olivier Toussaint
Establishment of H2O2-induced premature senescence in human fibroblasts concomitant with increased cellular production of H2O2.
Annals of the New York Academy of Sciences 2006;1067():210-6.
2005: Thierry Pascal; Florence Debacq-Chainiaux; Aline Chrétien; Coralie Bastin; Anne-France Dabée; Vincent Bertholet; José Remacle; Olivier Toussaint
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays.
FEBS letters 2005;579(17):3651-9.
2005: Florence Debacq-Chainiaux; Céline Borlon; Thierry Pascal; Véronique Royer; François Eliaers; Noelle Ninane; Géraldine Carrard; Bertrand Friguet; Françoise de Longueville; Sophie Boffe; José Remacle; Olivier Toussaint
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.
Journal of cell science 2005;118(Pt 4):743-58.
2005: Eric Matthews; Erica Haimes; Anne-Marie Duguet; Brian F C Clark; Christian Swine; Olivier Toussaint
Informed consent of very old patients and modern genomics.
Biogerontology 2005;6(1):81-4.
2005: João Pedro de Magalhães; Joana Costa; Olivier Toussaint
HAGR: the Human Ageing Genomic Resources.
Nucleic acids research 2005;33(Database issue):D537-43.
2004: João Pedro de Magalhães; Florence Chainiaux; Françoise de Longueville; Véronique Mainfroid; Valérie Migeot; Laurence Marcq; José Remacle; Michel Salmon; Olivier Toussaint
Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase.
Experimental gerontology 2004;39(9):1379-89.
2004: João Pedro de Magalhães; Olivier Toussaint
GenAge: a genomic and proteomic network map of human ageing.
FEBS letters 2004;571(1-3):243-7.
2004: João Pedro de Magalhães; Valérie Migeot; Véronique Mainfroid; Françoise de Longueville; José Remacle; Olivier Toussaint
No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.
Annals of the New York Academy of Sciences 2004;1019():375-8.
2004: João Pedro de Magalhães; Olivier Toussaint
How bioinformatics can help reverse engineer human aging.
Ageing research reviews 2004;3(2):125-41.
2004: Michel Salmon; Jérémie Dedessus Le Moutier; Frédéric Wenders; Sophie Chiarizia; François Eliaers; José Remacle; Véronique Royer; Thierry Pascal; Olivier Toussaint
Role of the PLA2-independent peroxiredoxin VI activity in the survival of immortalized fibroblasts exposed to cytotoxic oxidative stress.
FEBS letters 2004;557(1-3):26-32.
2004: João Pedro de Magalhães; Olivier Toussaint
Telomeres and telomerase: a modern fountain of youth?
Rejuvenation research 2004;7(2):126-33.
2003: Olivier Toussaint
Normal brain aging: a commentary.
Neurobiology of aging 2003;24 Suppl 1():S129-30; discussion S131.
2003: Géraldine Carrard; Marc Dieu; Martine Raes; Olivier Toussaint; Bertrand Friguet
Impact of ageing on proteasome structure and function in human lymphocytes.
The international journal of biochemistry & cell biology 2003;35(5):728-39.
2003: Christophe Frippiat; José Remacle; Olivier Toussaint
Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence.
The international journal of biochemistry & cell biology 2003;35(2):246-54.
2003: Jean-François Dierick; Frédéric Wenders; Florence Chainiaux; José Remacle; Aron B Fisher; Olivier Toussaint
Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB.
Biogerontology 2003;4(3):125-31.
2002: Jean-François Dierick; Dario E Kalume; Frédéric Wenders; Michel Salmon; Marc Dieu; Martine Raes; Peter Roepstorff; Olivier Toussaint
Identification of 30 protein species involved in replicative senescence and stress-induced premature senescence.
FEBS letters 2002;531(3):499-504.
2002: Christophe Frippiat; Janique Dewelle; José Remacle; Olivier Toussaint
Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts.
Free radical biology & medicine 2002;33(10):1334-46.
2002: Florence Chainiaux; José Remacle; Olivier Toussaint
Exposure of human skin diploid fibroblasts to repeated subcytotoxic doses of ultraviolet-B induces the overexpression of transforming growth factor-beta1 mRNA.
Annals of the New York Academy of Sciences 2002;973():44-8.
2002: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Stéphanie Zdanov; Joao Pedro Magalhaes; Véronique Royer; Florence Chainiaux
From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing.
The international journal of biochemistry & cell biology 2002;34(11):1415-29.
2002: Florence Chainiaux; Joao Pedro Magalhaes; François Eliaers; José Remacle; Olivier Toussaint
UVB-induced premature senescence of human diploid skin fibroblasts.
The international journal of biochemistry & cell biology 2002;34(11):1331-9.
2002: Jean-François Dierick; François Eliaers; José Remacle; Martine Raes; Stephen Fey; Peter Mose Larsen; Olivier Toussaint
Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence.
Biochemical pharmacology 2002;64(5-6):1011-7.
2002: Olivier Toussaint; Véronique Royer; Michel Salmon; José Remacle
Stress-induced premature senescence and tissue ageing.
Biochemical pharmacology 2002;64(5-6):1007-9.
2002: João Pedro de Magalhães; Florence Chainiaux; José Remacle; Olivier Toussaint
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts.
FEBS letters 2002;523(1-3):157-62.
2002: João Pedro de Magalhães; Olivier Toussaint
The evolution of mammalian aging.
Experimental gerontology 2002;37(6):769-75.
2002: Jean-François Dierick; Marc Dieu; José Remacle; Martine Raes; Peter Roepstorff; Olivier Toussaint
Proteomics in experimental gerontology.
Experimental gerontology 2002;37(5):721-34.
2002: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Véronique Royer; Florence Chainiaux
Approach of evolutionary theories of ageing, stress, senescence-like phenotypes, calorie restriction and hormesis from the view point of far-from-equilibrium thermodynamics.
Mechanisms of ageing and development 2002;123(8):937-46.
2002: Olivier Toussaint; Patrick Dumont; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Joao Pedro Magalhaes; Stéphanie Zdanov; Florence Chainiaux
Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two possible definitions?
TheScientificWorldJournal 2002;2():230-47.
2002: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Véronique Royer; Joao Pedro Magalhacs; Stéphanie Zdanov; Florence Chainiaux
Stress-induced premature senescence: from biomarkers to likeliness of in vivo occurrence.
Biogerontology 2002;3(1-2):13-7.
2002: Patrick Dumont; Florence Chainiaux; François Eliaers; Chariklia Petropoulou; José Remacle; Claudia Koch-Brandt; Efstathios S Gonos; Olivier Toussaint
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide.
Cell stress & chaperones 2002;7(1):23-35.
2001: Chariklia Petropoulou; Ioannis P Trougakos; Evangelos Kolettas; Olivier Toussaint; Efstathios S Gonos
Clusterin/apolipoprotein J is a novel biomarker of cellular senescence that does not affect the proliferative capacity of human diploid fibroblasts.
FEBS letters 2001;509(2):287-97.
2001: Patrick Dumont; Véronique Royer; Thierry Pascal; Jean-François Dierick; Florence Chainiaux; Christophe Frippiat; J P de Magalhaes; François Eliaers; José Remacle; Olivier Toussaint
Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress-induced premature senescence.
FEBS letters 2001;502(3):109-12.
2001: Olivier Toussaint; José Remacle; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Joao Pedro Magalhaes; F Chainaux
Hormesis: a quest for virtuality?
Human & experimental toxicology 2001;20(6):311-4; discussion 319-20.
2001: Christophe Frippiat; Qin M Chen; Stéphanie Zdanov; Joao Pedro Magalhaes; José Remacle; Olivier Toussaint
Subcytotoxic H2O2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts.
The Journal of biological chemistry 2001;276(4):2531-7.
2000: P Dumont; L Balbeur; J Remacle; Olivier Toussaint
Appearance of biomarkers of in vitro ageing after successive stimulation of WI-38 fibroblasts with IL-1alpha and TNF-alpha: senescence associated beta-galactosidase activity and morphotype transition.
Journal of anatomy 2000;197 Pt 4():529-37.
2000: Qin M Chen; Victoria C Tu; J Catania; M Burton; Olivier Toussaint; Tarrah K Dilley
Involvement of Rb family proteins, focal adhesion proteins and protein synthesis in senescent morphogenesis induced by hydrogen peroxide.
Journal of cell science 2000;113 ( Pt 22)():4087-97.
2000: Olivier Toussaint; Philippe Baret; Jean-Pierre Brion; Patrick cras; F Collette; P P De Deyn ; V Geenen; Pascal Kienlen-Campard; C Labeur; J J Legros; J Nève; Jean-Noël Octave; G E Piérard; E Salmon; P van den Bosch de Aguilar P; M Van der Linden ; F V Leuven; J Vanfleteren
Experimental gerontology in Belgium: from model organisms to age-related pathologies.
Experimental gerontology 2000;35(8):901-16.
2000: Olivier Toussaint; J Remacle; Brian F C Clark; Efstathios S Gonos; C Franceschi; T B Kirkwood
Biology of ageing.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(10):954-6.
2000: Christophe Frippiat; Qin M Chen; José Remacle; Olivier Toussaint
Cell cycle regulation in H(2)O(2)-induced premature senescence of human diploid fibroblasts and regulatory control exerted by the papilloma virus E6 and E7 proteins.
Experimental gerontology 2000;35(6-7):733-45.
2000: Patrick Dumont; M Burton; Qin M Chen; Christophe Frippiat; Thierry Pascal; Jean-François Dierick; François Eliaers; Florence Chainiaux; José Remacle; Olivier Toussaint
Human diploid fibroblasts display a decreased level of c-fos mRNA at 72 hours after exposure to sublethal H2O2 stress.
Annals of the New York Academy of Sciences 2000;908():306-9.
2000: Jean-François Dierick; Thierry Pascal; Florence Chainiaux; François Eliaers; José Remacle; Peter Mose Larsen; Peter Roepstorff; Olivier Toussaint
Transcriptome and proteome analysis in human senescent fibroblasts and fibroblasts undergoing premature senescence induced by repeated sublethal stresses.
Annals of the New York Academy of Sciences 2000;908():302-5.
2000: Olivier Toussaint; Patrick Dumont; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Florence Chainiaux; F Sluse; François Eliaers; José Remacle
Stress-induced premature senescence. Essence of life, evolution, stress, and aging.
Annals of the New York Academy of Sciences 2000;908():85-98.
2000: Patrick Dumont; M Burton; Qin M Chen; Efstathios S Gonos; Christophe Frippiat; J B Mazarati; François Eliaers; José Remacle; Olivier Toussaint
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast.
Free radical biology & medicine 2000;28(3):361-73.
2000: Olivier Toussaint; Patrick Dumont; Jean-François Dierick; Thierry Pascal; Christophe Frippiat; Florence Chainiaux; Joao Pedro Magalhaes; François Eliaers; José Remacle
Stress-induced premature senescence as alternative toxicological method for testing the long-term effects of molecules under development in the industry.
Biogerontology 2000;1(2):179-83.
2000: Christophe Frippiat; Jean-François Dierick; José Remacle; Olivier Toussaint
Consideration of heteroduplexes and homoduplexes for the quantification by competitive PCR of human mitochondrial DNA deletions with ageing of tissues and cells.
Biogerontology 2000;1(3):279-83.
1998: Olivier Toussaint; S Y Fuchs; Z A Ronai; S Isoyama; N Yuko; Valeria Petronilli; Paolo Bernardi; Efstathios S Gonos; Patrick Dumont; José Remacle
Reciprocal relationships between the resistance to stresses and cellular aging.
Annals of the New York Academy of Sciences 1998;851():450-65.