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Pierre-Louis Toutain

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Alain Regnier; Anne Gautier-Bouchardon; Véronique Gayrard; Valérie Laroute; Nicole Picard-Hagen; Pierre-Louis Toutain
Florfenicol concentrations in ovine tear fluid following intramuscular and subcutaneous administration and comparison with the minimum inhibitory concentrations against mycoplasmal strains potentially involved in infectious keratoconjunctivitis.
Catherine Viguié; COLLET Severine; Véronique Gayrard; Nicole Picard-Hagen; Sylvie Puel; Béatrice B Roques; Pierre-Louis Toutain; Marlène Z Lacroix
Maternal and fetal exposure to bisphenol a is associated with alterations of thyroid function in pregnant ewes and their newborn lambs.
R P Hunter; Peter Lees; D Concordet; Pierre-Louis Toutain
Establishing bioequivalence of veterinary premixes (Type A medicated articles).

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2013: Alain Regnier; Anne Gautier-Bouchardon; Véronique Gayrard; Valérie Laroute; Nicole Picard-Hagen; Pierre-Louis Toutain
Florfenicol concentrations in ovine tear fluid following intramuscular and subcutaneous administration and comparison with the minimum inhibitory concentrations against mycoplasmal strains potentially involved in infectious keratoconjunctivitis.
American journal of veterinary research 2013;74(2):268-74.
2013: Catherine Viguié; COLLET Severine; Véronique Gayrard; Nicole Picard-Hagen; Sylvie Puel; Béatrice B Roques; Pierre-Louis Toutain; Marlène Z Lacroix
Maternal and fetal exposure to bisphenol a is associated with alterations of thyroid function in pregnant ewes and their newborn lambs.
Endocrinology 2013;154(1):521-8.
2012: R P Hunter; Peter Lees; D Concordet; Pierre-Louis Toutain
Establishing bioequivalence of veterinary premixes (Type A medicated articles).
Journal of veterinary pharmacology and therapeutics 2012;35 Suppl 1():53-63.
2011: Véronique Gayrard; Nicole Picard-Hagen; Catherine Viguié; Pierre-Louis Toutain
Competitive binding to plasma thyroid hormone transport proteins and thyroid disruption by phenylbutazone used as a probe.
General and comparative endocrinology 2011;174(2):225-31.
2011: Dalia KHACHMAN; Jean-Marie Conil; Bernard Georges; Georges Houin; Sylvie Saivin; Pierre-Louis Toutain; Celine M Laffont
Optimizing ciprofloxacin dosing in intensive care unit patients through the use of population pharmacokinetic-pharmacodynamic analysis and Monte Carlo simulations.
The Journal of antimicrobial chemotherapy 2011;66(8):1798-809.
2011: Alain Bousquet-Mélou; Philippe Jacquiet; Hervé Hoste; Julien Clément; Jean-Paul Bergeaud; Michel Alvinerie; Pierre-Louis Toutain
Licking behaviour induces partial anthelmintic efficacy of ivermectin pour-on formulation in untreated cattle.
International journal for parasitology 2011;41(5):563-9.
2011: Aude A Ferran; Pierre-Louis Toutain; Alain Bousquet-Mélou
Impact of early versus later fluoroquinolone treatment on the clinical; microbiological and resistance outcomes in a mouse-lung model of Pasteurella multocida infection.
Veterinary microbiology 2011;148(2-4):292-7.
2011: Alain Regnier; François Schelcher; Olivier Albaric; Olivier Andreoletti; Delphine Cayez Gruson; Pierre-Louis Toutain
Clinical, electroretinographic and histomorphometric evaluation of the retina in sheep with natural scrapie.
BMC veterinary research 2011;7():25.
2010: COLLET Severine; Nicole Picard-Hagen; Catherine Viguié; Marlène Z Lacroix; Pierre-Louis Toutain; Véronique Gayrard
Estrogenicity of bisphenol a: a concentration-effect relationship on luteinizing hormone secretion in a sensitive model of prepubertal lamb.
Toxicological sciences : an official journal of the Society of Toxicology 2010;117(1):54-62.
2010: M Z Lacroix; S Puel; Pierre-Louis Toutain; Catherine Viguié
Quantification of fipronil and its metabolite fipronil sulfone in rat plasma over a wide range of concentrations by LC/UV/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(22):1934-8.
2010: Anne-Sylvie Kesteman; Agnès Perrin-Guyomard; Michel Laurentie; Pascal Sanders; Pierre-Louis Toutain; Alain Bousquet-Mélou
Emergence of resistant Klebsiella pneumoniae in the intestinal tract during successful treatment of Klebsiella pneumoniae lung infection in rats.
Antimicrobial agents and chemotherapy 2010;54(7):2960-4.
2010: Julien Leghait; Véronique Gayrard; Pierre-Louis Toutain; Nicole Picard-Hagen; Catherine Viguié
Is the mechanisms of fipronil-induced thyroid disruption specific of the rat: Re-evaluation of fipronil thyroid toxicity in sheep?
Toxicology letters 2010;194(3):51-7.
2010: Pierre-Louis Toutain
How to extrapolate a withdrawal time from an EHSLC published detection time: a Monte Carlo simulation appraisal.
Equine veterinary journal 2010;42(3):248-54.
2010: E C Authie; Patrice Garcia; Marie-Agnès Popot; Pierre-Louis Toutain; M Doucet
Effect of an endurance-like exercise on the disposition and detection time of phenylbutazone and dexamethasone in the horse: application to medication control.
Equine veterinary journal 2010;42(3):240-7.
2010: Pierre-Louis Toutain
Veterinary medicines and competition animals: the question of medication versus doping control.
Handbook of experimental pharmacology 2010;(199):315-39.
2010: Pierre-Louis Toutain; aude ferran; Alain Bousquet-Mélou
Species differences in pharmacokinetics and pharmacodynamics.
Handbook of experimental pharmacology 2010;(199):19-48.
2009: Anne-Sylvie Kesteman; aude ferran; Agnès Perrin-Guyomard; Michel Laurentie; Pascal Sanders; Pierre-Louis Toutain; Alain Bousquet-Mélou
Influence of inoculum size and marbofloxacin plasma exposure on the amplification of resistant subpopulations of Klebsiella pneumoniae in a rat lung infection model.
Antimicrobial agents and chemotherapy 2009;53(11):4740-8.
2009: aude ferran; Anne-Sylvie Kesteman; Pierre-Louis Toutain; Alain Bousquet-Mélou
Pharmacokinetic/pharmacodynamic analysis of the influence of inoculum size on the selection of resistance in Escherichia coli by a quinolone in a mouse thigh bacterial infection model.
Antimicrobial agents and chemotherapy 2009;53(8):3384-90.
2009: D Bibbal; Véronique Dupouy; Marie-Françoise Prère; Pierre-Louis Toutain; Alain Bousquet-Mélou
Relatedness of Escherichia coli strains with different susceptibility phenotypes isolated from swine feces during ampicillin treatment.
Applied and environmental microbiology 2009;75(10):2999-3006.
2009: Catherine Viguié; Nicole Picard-Hagen; Véronique Gayrard; Pierre-Louis Toutain
Increased GH secretion in scrapie, a prion-associated neurodegenerative disease, is not due to suppressed IGF-1 negative feedback.
Domestic animal endocrinology 2009;36(3):127-37.
2009: Jérôme M Giraudel; Pierre-Louis Toutain; J N King; Peter Lees
Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib.
Journal of veterinary pharmacology and therapeutics 2009;32(1):31-40.
2009: J M Giraudel; J N King; E C Jeunesse; P Lees; Pierre-Louis Toutain
Use of a pharmacokinetic/pharmacodynamic approach in the cat to determine a dosage regimen for the COX-2 selective drug robenacoxib.
Journal of veterinary pharmacology and therapeutics 2009;32(1):18-30.
2008: Véronique Gayrard; Nicole Picard-Hagen; Catherine Viguié; Elisabeth Jeunesse; Guillaume Tabouret; Human Rezaei; Pierre-Louis Toutain
Blood clearance of the prion protein introduced by intravenous route in sheep is influenced by host genetic and physiopathologic factors.
Transfusion 2008;48(4):609-19.
2008: Alain Regnier; Marc Schneider; Didier Concordet; Pierre-Louis Toutain
Intraocular pharmacokinetics of intravenously administered marbofloxacin in rabbits with experimentally induced acute endophthalmitis.
American journal of veterinary research 2008;69(3):410-5.
2007: Pierre-Louis Toutain; Alain Bousquet-Mélou; Marilyn Martinez
AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor?
The Journal of antimicrobial chemotherapy 2007;60(6):1185-8.
2007: aude ferran; Véronique Dupouy; Pierre-Louis Toutain; Alain Bousquet-Mélou
Influence of inoculum size on the selection of resistant mutants of Escherichia coli in relation to mutant prevention concentrations of marbofloxacin.
Antimicrobial agents and chemotherapy 2007;51(11):4163-6.
2007: E Lallemand; Anne Lespine; Michel Alvinerie; Alain Bousquet-Melou; Pierre-Louis Toutain
Estimation of absolute oral bioavailability of moxidectin in dogs using a semi-simultaneous method: influence of lipid co-administration.
Journal of veterinary pharmacology and therapeutics 2007;30(5):375-80.
2007: D Bibbal; Véronique Dupouy; J P Ferré; Pierre-Louis Toutain; Olivier Fayet; Marie-Françoise Prère; Alain Bousquet-Mélou
Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of blaTEM genes in swine feces.
Applied and environmental microbiology 2007;73(15):4785-90.
2007: Pierre J Ferré; Laurence Liaubet; Didier Concordet; Magali SanCristobal; Emmanuelle Uro-Coste; Gwenola Tosser-Klopp; Agnès Bonnet; Pierre-Louis Toutain; François Hatey; Hervé P Lefebvre
Longitudinal analysis of gene expression in porcine skeletal muscle after post-injection local injury.
Pharmaceutical research 2007;24(8):1480-9.
2007: Marie-Agnès Popot; L Menaut; S Boyer; Yves Bonnaire; Pierre-Louis Toutain
Spurious urine excretion drug profile in the horse due to bedding contamination and drug recycling: the case of meclofenamic acid.
Journal of veterinary pharmacology and therapeutics 2007;30(2):179-84.
2007: Hervé P Lefebvre; S A Brown; V Chetboul; JN King; J-L Pouchelon; Pierre-Louis Toutain
Angiotensin-converting enzyme inhibitors in veterinary medicine.
Current pharmaceutical design 2007;13(13):1347-61.
2006: Nicole Picard-Hagen; Véronique Gayrard; Catherine Viguié; Mohammed Moudjou; Chantal Imbs; Pierre-Louis Toutain
Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep.
The Journal of general virology 2006;87(Pt 12):3723-7.
2006: J R E del Castillo; Valérie Laroute; P Pommier; C Zémirline; A Keïta; Didier Concordet; Pierre-Louis Toutain
Interindividual variability in plasma concentrations after systemic exposure of swine to dietary doxycycline supplied with and without paracetamol: a population pharmacokinetic approach.
Journal of animal science 2006;84(11):3155-66.
2006: Alain Bousquet-Mélou; Enrique Formentini; Nicole Picard-Hagen; Laure Delage; Valérie Laroute; Pierre-Louis Toutain
The adrenocorticotropin stimulation test: contribution of a physiologically based model developed in horse for its interpretation in different pathophysiological situations encountered in man.
Endocrinology 2006;147(9):4281-91.
2006: Hervé P Lefebvre; Elisabeth Jeunesse; Valérie Laroute; Pierre-Louis Toutain
Pharmacokinetic and pharmacodynamic parameters of ramipril and ramiprilat in healthy dogs and dogs with reduced glomerular filtration rate.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 2006;20(3):499-507.
2006: Pierre Ferre; Valérie Laroute; Jean-Pierre Braun; J Cazaux; Pierre-Louis Toutain; Hervé P Lefebvre
Simultaneous and minimally invasive assessment of muscle tolerance and bioavailability of different volumes of an intramuscular formulation in the same animals.
Journal of animal science 2006;84(5):1295-301.
2006: Anne Lespine; Guillaume Chanoit; Alain Bousquet-Melou; Elodie Lallemand; Firas Mohamad Bassissi; Michel Alvinerie; Pierre-Louis Toutain
Contribution of lymphatic transport to the systemic exposure of orally administered moxidectin in conscious lymph duct-cannulated dogs.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;27(1):37-43.
2005: Jérôme M Giraudel; Armelle Diquélou; Valérie Laroute; Peter Lees; Pierre-Louis Toutain
Pharmacokinetic/pharmacodynamic modelling of NSAIDs in a model of reversible inflammation in the cat.
British journal of pharmacology 2005;146(5):642-53.
2005: Jérôme M Giraudel; Armelle Diquélou; Peter Lees; Pierre-Louis Toutain
Development and validation of a new model of inflammation in the cat and selection of surrogate endpoints for testing anti-inflammatory drugs.
Journal of veterinary pharmacology and therapeutics 2005;28(3):275-85.
2005: Jérôme M Giraudel; Pierre-Louis Toutain; Peter Lees
Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in cats.
American journal of veterinary research 2005;66(4):700-9.
2005: Pierre Jean Ferré; Eckart Thein; Isabelle Raymond-Letron; Pierre-Louis Toutain; Hervé P Lefebvre
Acute changes in muscle blood flow and concomitant muscle damage after an intramuscular administration.
Pharmaceutical research 2005;22(3):405-12.
2005: Véronique Gayrard; Nicole Picard-Hagen; Catherine Viguié; Valérie Laroute; Olivier Andréoletti; Pierre-Louis Toutain
A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie.
British journal of pharmacology 2005;144(3):386-93.
2004: Pierre-Louis Toutain; H P Lefèbvre
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationships for angiotensin-converting enzyme inhibitors.
Journal of veterinary pharmacology and therapeutics 2004;27(6):515-25.
2004: Peter Lees; Jérôme M Giraudel; Maria Fabiana Landoni; Pierre-Louis Toutain
PK-PD integration and PK-PD modelling of nonsteroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology.
Journal of veterinary pharmacology and therapeutics 2004;27(6):491-502.
2004: Peter Lees; Maria Fabiana Landoni; Jérôme M Giraudel; Pierre-Louis Toutain
Pharmacodynamics and pharmacokinetics of nonsteroidal anti-inflammatory drugs in species of veterinary interest.
Journal of veterinary pharmacology and therapeutics 2004;27(6):479-90.
2004: Pierre-Louis Toutain; P Lees
Integration and modelling of pharmacokinetic and pharmacodynamic data to optimize dosage regimens in veterinary medicine.
Journal of veterinary pharmacology and therapeutics 2004;27(6):467-77.
2004: Pierre-Louis Toutain; Alain Bousquet-Mélou
Bioavailability and its assessment.
Journal of veterinary pharmacology and therapeutics 2004;27(6):455-66.
2004: Pierre-Louis Toutain; Alain Bousquet-Mélou
Volumes of distribution.
Journal of veterinary pharmacology and therapeutics 2004;27(6):441-53.
2004: Pierre-Louis Toutain; Alain Bousquet-Mélou
Plasma terminal half-life.
Journal of veterinary pharmacology and therapeutics 2004;27(6):427-39.
2004: Pierre-Louis Toutain; Alain Bousquet-Mélou
Plasma clearance.
Journal of veterinary pharmacology and therapeutics 2004;27(6):415-25.
2004: Pierre-Louis Toutain; Nadège Reymond; Valérie Laroute; Patrice Garcia; Marie-Agnès Popot; Yves Bonnaire; Alexandra Hirsch; Rüdiger Narbe
Pharmacokinetics of meloxicam in plasma and urine of horses.
American journal of veterinary research 2004;65(11):1542-7.
2004: Pierre-Louis Toutain; Corinne C Cester
Pharmacokinetic-pharmacodynamic relationships and dose response to meloxicam in horses with induced arthritis in the right carpal joint.
American journal of veterinary research 2004;65(11):1533-41.
2004: Catherine Viguié; Y Chilliard; Véronique Gayrard; Nicole Picard-Hagen; P Monget; A Dutour; Pierre-Louis Toutain
Alterations of somatotropic function in prion disease in sheep.
The Journal of endocrinology 2004;183(2):427-35.
2004: Herve Lefebvre; Pierre-Louis Toutain
Angiotensin-converting enzyme inhibitors in the therapy of renal diseases.
Journal of veterinary pharmacology and therapeutics 2004;27(5):265-81.
2004: Alain Bousquet-Mélou; Sonia Mercadier; Michel Alvinerie; Pierre-Louis Toutain
Endectocide exchanges between grazing cattle after pour-on administration of doramectin, ivermectin and moxidectin.
International journal for parasitology 2004;34(11):1299-307.
2004: Marie-Agnès Popot; Yves Bonnaire; J Guéchot; Pierre-Louis Toutain
Hyaluronan in horses: physiological production rate, plasma and synovial fluid concentrations in control conditions and following sodium hyaluronate administration.
Equine veterinary journal 2004;36(6):482-7.
2004: Nathalie M-H Priymenko; Gary D Koritz; Jean-Pierre Ferre; Valérie Laroute; Pierre-Louis Toutain
Influence of feeding and analytical method on the bioequivalence of a racemic drug undergoing enantioselective enterohepatic recycling.
Journal of pharmaceutical sciences 2004;93(3):590-600.
2003: Céline M Laffont; Alain Bousquet-Mélou; David Bralet; Michel Alvinerie; Johanna Fink-Gremmels; Pierre-Louis Toutain
A pharmacokinetic model to document the actual disposition of topical ivermectin in cattle.
Veterinary research 2003;34(4):445-60.
2003: Alain Regnier; Didier Concordet; Marc Schneider; Bernard Boisramé; Pierre-Louis Toutain
Population pharmacokinetics of marbofloxacin in aqueous humor after intravenous administration in dogs.
American journal of veterinary research 2003;64(7):889-93.
2003: JN King; M Maurer; Pierre-Louis Toutain
Pharmacokinetic/pharmacodynamic modelling of the disposition and effect of benazepril and benazeprilat in cats.
Journal of veterinary pharmacology and therapeutics 2003;26(3):213-24.
2002: Pierre-Louis Toutain; Alain Bousquet-Melou
Free drug fraction vs free drug concentration: a matter of frequent confusion.
Journal of veterinary pharmacology and therapeutics 2002;25(6):460-3.
2002: Alain Bousquet-Melou; Céline M Laffont; Valérie Laroute; Pierre-Louis Toutain
Modelling the loss of metabolic capacities of cultured hepatocytes: application to measurement of Michaelis-Menten kinetic parameters in in vitro systems.
Xenobiotica; the fate of foreign compounds in biological systems 2002;32(10):895-906.
2002: Pierre-Louis Toutain; J R E del Castillo; Alain Bousquet-Mélou
The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics.
Research in veterinary science 2002;73(2):105-14.
2002: Alain Bousquet-Melou; S Bernard; M Schneider; Pierre-Louis Toutain
Pharmacokinetics of marbofloxacin in horses.
Equine veterinary journal 2002;34(4):366-72.
2002: Alain Bousquet-Melou; Pierre-Louis Toutain
Effects of altered plasma alpha1-acid glycoprotein levels on pharmacokinetics of some basic antibiotics in pigs: simulation analysis.
Journal of veterinary pharmacology and therapeutics 2002;25(3):239.
2002: Nicole Picard-Hagen; Véronique Gayrard; Valérie Laroute; C Grandjean; Olivier Andreoletti; Jean-Michel Elsen; François Schelcher; Pierre-Louis Toutain
Discriminant value of blood and urinary corticoids for the diagnosis of scrapie in live sheep.
The Veterinary record 2002;150(22):680-4.
2002: Céline M Laffont; Pierre-Louis Toutain; Michel Alvinerie; Alain Bousquet-Mélou
Intestinal secretion is a major route for parent ivermectin elimination in the rat.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(6):626-30.
2002: A D J Watson; Hervé P Lefebvre; Didier Concordet; Valérie Laroute; Jean-Pierre Ferré; Jean-Pierre Braun; Fabrice Conchou; Pierre-Louis Toutain
Plasma exogenous creatinine clearance test in dogs: comparison with other methods and proposed limited sampling strategy.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 2002;16(1):22-33.
2001: Céline M Laffont; Michel Alvinerie; Alain Bousquet-Mélou; Pierre-Louis Toutain
Licking behaviour and environmental contamination arising from pour-on ivermectin for cattle.
International journal for parasitology 2001;31(14):1687-92.
2001: Nicole Picard-Hagen; Véronique Gayrard; Michel Alvinerie; H Smeyers; R Ricou; Alain Bousquet-Melou; Pierre-Louis Toutain
A nonlabeled method to evaluate cortisol production rate by modeling plasma CBG-free cortisol disposition.
American journal of physiology. Endocrinology and metabolism 2001;281(5):E946-56.
2001: Guillaume Chanoit; Hervé P Lefebvre; K Orcel; Valérie Laroute; Pierre-Louis Toutain; Jean-Pierre Braun
Use of plasma creatine kinase pharmacokinetics to estimate the amount of excercise-induced muscle damage in Beagles.
American journal of veterinary research 2001;62(9):1375-80.
2001: Hervé P Lefebvre; J P Ferré; A D J Watson; C A Brown; J P Serthelon; Valérie Laroute; Didier Concordet; Pierre-Louis Toutain
Small bowel motility and colonic transit are altered in dogs with moderate renal failure.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(1):R230-8.
2001: Pierre-Louis Toutain; Corinne C Cester; T Haak; Valérie Laroute
A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: the case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog.
Journal of veterinary pharmacology and therapeutics 2001;24(1):43-55.
2001: Pierre-Louis Toutain; Corinne C Cester; T Haak; S Metge
Pharmacokinetic profile and in vitro selective cyclooxygenase-2 inhibition by nimesulide in the dog.
Journal of veterinary pharmacology and therapeutics 2001;24(1):35-42.
2000: Nicole Picard-Hagen; Véronique Gayrard; Michel Alvinerie; Valérie Laroute; C Touron; Olivier Andreoletti; Pierre-Louis Toutain
Naturally occurring scrapie is associated with a lower CBG binding capacity in ewes.
The Journal of endocrinology 2000;165(2):527-32.
2000: Véronique Gayrard; Nicole Picard-Hagen; Michel Grino; Nicole Sauze; C Grandjean; J Galea; Olivier Andreoletti; François Schelcher; Pierre-Louis Toutain
Major hypercorticism is an endocrine feature of ewes with naturally occurring scrapie.
Endocrinology 2000;141(3):988-94.
2000: Pierre-Louis Toutain; Hervé P Lefebvre; Valérie Laroute
New insights on effect of kidney insufficiency on disposition of angiotensin-converting enzyme inhibitors: case of enalapril and benazepril in dogs.
The Journal of pharmacology and experimental therapeutics 2000;292(3):1094-103.
2000: Pierre-Louis Toutain; Hervé P Lefebvre; JN King
Benazeprilat disposition and effect in dogs revisited with a pharmacokinetic/pharmacodynamic modeling approach.
The Journal of pharmacology and experimental therapeutics 2000;292(3):1087-93.
2000: Jean-Pierre Braun; Didier Concordet; M Lyazrhi; Hervé P Lefebvre; Pierre-Louis Toutain
Overestimation of the predictive value of positives by the usual calculations of the specificity of diagnostic tests.
Veterinary research communications 2000;24(1):17-24.
1999: Marie-Agnès Popot; E Lacabaratz; Patrice Garcia; Valérie Laroute; Yves Bonnaire; Pierre-Louis Toutain; David A Cowan
New approaches to detect cortisol administration in the horse.
Equine veterinary journal 1999;31(4):278-84.
1999: François Schelcher; Nicole Picard-Hagen; Valérie Laroute; Véronique Gayrard; Marie-Agnès Popot; Olivier Andreoletti; Pierre-Louis Toutain
Corticoid concentrations are increased in the plasma and urine of ewes with naturally occurring scrapie.
Endocrinology 1999;140(5):2422-5.
1999: Valérie Laroute; Hervé P Lefebvre; G Costes; Pierre-Louis Toutain
Measurement of glomerular filtration rate and effective renal plasma flow in the conscious beagle dog by single intravenous bolus of iohexol and p-aminohippuric acid.
Journal of pharmacological and toxicological methods 1999;41(1):17-25.
1999: Véronique Gayrard; Michel Alvinerie; Pierre-Louis Toutain
Comparison of pharmacokinetic profiles of doramectin and ivermectin pour-on formulations in cattle.
Veterinary parasitology 1999;81(1):47-55.
1999: Hervé P Lefebvre; Valérie Laroute; Didier Concordet; Pierre-Louis Toutain
Effects of renal impairment on the disposition of orally administered enalapril, benazepril, and their active metabolites.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 1999;13(1):21-7.
1998: Hervé P Lefebvre; M Schneider; Véronique Dupouy; Valérie Laroute; G Costes; L Delesalle; Pierre-Louis Toutain
Effect of experimental renal impairment on disposition of marbofloxacin and its metabolites in the dog.
Journal of veterinary pharmacology and therapeutics 1998;21(6):453-61.
1998: Nicole Picard-Hagen; Véronique Gayrard; Olivier Andreoletti; J Galea; C Grandjean; F Mandon-Maurice; P Cabanié; François Schelcher; Pierre-Louis Toutain
Melatonin and prolactin secretion profile in naturally occurring scrapie in ewe.
Journal of pineal research 1998;24(2):117-22.
1998: N Priymenko; F Garnier; J P Ferre; P Delatour; Pierre-Louis Toutain
Enantioselectivity of the enterohepatic recycling of carprofen in the dog.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(2):170-6.
1998: Hervé P Lefebvre; Véronique Dupouy; M Schneider; Valérie Laroute; Pierre-Louis Toutain
Pharmacokinetics of marbofloxacin in renal impairment in the dog.
The Veterinary quarterly 1998;20 Suppl 1():S104.
1997: B M Aktas; P Vinclair; A Autefage; Hervé P Lefebvre; Pierre-Louis Toutain; Jean-Pierre Braun
In vivo quantification of muscle damage in dogs after general anaesthesia with halothane and propofol.
The Journal of small animal practice 1997;38(12):565-9.
1997: Didier Concordet; Pierre-Louis Toutain
The withdrawal time estimation of veterinary drugs revisited.
Journal of veterinary pharmacology and therapeutics 1997;20(5):380-6.
1997: Didier Concordet; Pierre-Louis Toutain
The withdrawal time estimation of veterinary drugs: a non-parametric approach.
Journal of veterinary pharmacology and therapeutics 1997;20(5):374-9.
1997: Corinne C Cester; Pierre-Louis Toutain
A comprehensive model for enrofloxacin to ciprofloxacin transformation and disposition in dog.
Journal of pharmaceutical sciences 1997;86(10):1148-55.
1997: Pierre-Louis Toutain; D W Upson; T N Terhune; M E McKenzie
Comparative pharmacokinetics of doramectin and ivermectin in cattle.
Veterinary parasitology 1997;72(1):3-8.
1997: Marie-Agnès Popot; Ed Houghton; A Ginn; M Jones; Philip Teale; TP Samuels; V Lassourd; N Dunnett; David A Cowan; Yves Bonnaire; Pierre-Louis Toutain
Cortisol concentrations in post competition horse urine: a French and British survey.
Equine veterinary journal 1997;29(3):226-9.
1997: Pierre-Louis Toutain; Gary D Koritz
Veterinary drug bioequivalence determination.
Journal of veterinary pharmacology and therapeutics 1997;20(2):79-90.
1997: Hervé P Lefebvre; Valérie Laroute; Michel Alvinerie; M Schneider; P Vinclair; Jean-Pierre Braun; Pierre-Louis Toutain
The effect of experimental renal failure on tolfenamic acid disposition in the dog.
Biopharmaceutics & drug disposition 1997;18(1):79-91.
1996: V Lassourd; Véronique Gayrard; Valérie Laroute; Michel Alvinerie; P Benard; D Courtot; Pierre-Louis Toutain
Cortisol disposition and production rate in horses during rest and exercise.
The American journal of physiology 1996;271(1 Pt 2):R25-33.
1996: Hervé P Lefebvre; Valérie Laroute; Jean-Pierre Braun; V Lassourd; Pierre-Louis Toutain
Non-invasive and quantitative evaluation of post-injection muscle damage by pharmacokinetic analysis of creatine kinase release.
Veterinary research 1996;27(4-5):343-61.
1996: Véronique Gayrard; Michel Alvinerie; Pierre-Louis Toutain
Interspecies variations of corticosteroid-binding globulin parameters.
Domestic animal endocrinology 1996;13(1):35-45.
1995: Pierre-Louis Toutain; V Lassourd; G Costes; Michel Alvinerie; L Bret; Hervé P Lefebvre; Jean-Pierre Braun
A non-invasive and quantitative method for the study of tissue injury caused by intramuscular injection of drugs in horses.
Journal of veterinary pharmacology and therapeutics 1995;18(3):226-35.
1995: Yves Bonnaire; L Dehennin; P Plou; Pierre-Louis Toutain
Testosterone administration to mares: criteria for detection of testosterone abuse by analysis of metabolites in plasma and urine.
Journal of analytical toxicology 1995;19(3):175-81.
1995: P Houpert; J P Serthelon; Hervé P Lefebvre; Pierre-Louis Toutain; Jean-Pierre Braun
In vivo non-invasive quantification of muscle damage following a single intramuscular injection of phenylbutazone in sheep.
Veterinary and human toxicology 1995;37(2):105-10.
1995: M Aktas; P Vinclair; Hervé P Lefebvre; Pierre-Louis Toutain; Jean-Pierre Braun
In vivo quantification of muscle damage in dogs after intramuscular administration of drugs.
The British veterinary journal 1995;151(2):189-96.
1995: M Aktas; Hervé P Lefebvre; Pierre-Louis Toutain; Jean-Pierre Braun
Disposition of creatine kinase activity in dog plasma following intravenous and intramuscular injection of skeletal muscle homogenates.
Journal of veterinary pharmacology and therapeutics 1995;18(1):1-6.
1994: M A Botrel; T Haak; C Legrand; Didier Concordet; R Chevalier; Pierre-Louis Toutain
Quantitative evaluation of an experimental inflammation induced with Freund's complete adjuvant in dogs.
Journal of pharmacological and toxicological methods 1994;32(2):63-71.
1994: Hervé P Lefebvre; Pierre-Louis Toutain; J P Serthelon; V Lassourd; L Gardey; Jean-Pierre Braun
Pharmacokinetic variables and bioavailability from muscle of creatine kinase in cattle.
American journal of veterinary research 1994;55(4):487-93.
1994: L Volfinger; V Lassourd; J M Michaux; Jean-Pierre Braun; Pierre-Louis Toutain
Kinetic evaluation of muscle damage during exercise by calculation of amount of creatine kinase released.
The American journal of physiology 1994;266(2 Pt 2):R434-41.
1994: M Aktas; D Auguste; Didier Concordet; P Vinclair; Hervé P Lefebvre; Pierre-Louis Toutain; Jean-Pierre Braun
Creatine kinase in dog plasma: preanalytical factors of variation, reference values and diagnostic significance.
Research in veterinary science 1994;56(1):30-6.
1993: N Priymenko; J P Ferre; A Rascol; G Costes; Pierre-Louis Toutain
Migrating motor complex of the intestine and absorption of a biliary excreted drug in the dog.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1161-7.
1993: X Berthelot; J P Ravault; Didier Concordet; J Ferney; Pierre-Louis Toutain
Absence of circadian rhythm in the disposition of melatonin in the cow.
Journal of pineal research 1993;15(3):141-6.
1993: M Aktas; D Auguste; Hervé P Lefebvre; Pierre-Louis Toutain; Jean-Pierre Braun
Creatine kinase in the dog: a review.
Veterinary research communications 1993;17(5):353-69.
1993: Hervé P Lefebvre; Pierre-Louis Toutain; L Bret; A G Rico; Jean-Pierre Braun
Compared kinetics of plasma creatine kinase activity in rabbits after intravenous injection of different preparations of skeletal muscle.
Veterinary research 1993;24(6):468-76.
1992: Hervé P Lefebvre; J P Jaeg; A G Rico; Pierre-Louis Toutain; Jean-Pierre Braun
Variations of plasma creatine kinase in rabbits following repetitive blood sampling effects of pretreatment with acepromazine, carazolol and dantrolene.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1992;30(7):425-8.
1992: Hervé P Lefebvre; Ana Cardona; Pierre-Louis Toutain; E Morel; Jean-François Bach; B Vernet-der-Garabedian
A simple method for the quantitative evaluation of neuromuscular blockade in mice.
Journal of pharmacological and toxicological methods 1992;27(3):129-33.