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Klaus Toyka

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Niels Hansen; Claudia Sommer; Klaus V Toyka; Andreas Weishaupt; Maria Nandini Colaço; Benedikt Grünewald; Christian Geis
Human Stiff person syndrome IgG-containing high-titer anti-GAD65 autoantibodies induce motor dysfunction in rats.
Michael Horn; Tessa Lühmann; Jorge A Pereira; João B Relvas; Jan Senderek; Páris N M Sidiropoulos; Christian Somandin; Claudia Stendel; Klaus V Toyka; Hans Welzl; Carsten Wessig; Reto Baumann; Ueli Suter
Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells.
Marco Morsch; Stephen W Reddel; Klaus V Toyka; Nazanin Ghazanfari; William D Phillips
Muscle specific kinase autoantibodies cause synaptic failure through progressive wastage of postsynaptic acetylcholine receptors.

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2013: Niels Hansen; Claudia Sommer; Klaus V Toyka; Andreas Weishaupt; Maria Nandini Colaço; Benedikt Grünewald; Christian Geis
Human Stiff person syndrome IgG-containing high-titer anti-GAD65 autoantibodies induce motor dysfunction in rats.
Experimental neurology 2013;239():202-9.
2012: Michael Horn; Tessa Lühmann; Jorge A Pereira; João B Relvas; Jan Senderek; Páris N M Sidiropoulos; Christian Somandin; Claudia Stendel; Klaus V Toyka; Hans Welzl; Carsten Wessig; Reto Baumann; Ueli Suter
Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells.
Brain : a journal of neurology 2012;135(Pt 12):3567-83.
2012: Marco Morsch; Stephen W Reddel; Klaus V Toyka; Nazanin Ghazanfari; William D Phillips
Muscle specific kinase autoantibodies cause synaptic failure through progressive wastage of postsynaptic acetylcholine receptors.
Experimental neurology 2012;237(2):286-95.
2012: Christian Geis; Benedikt Grünewald; Andreas Reif; Klaus V Toyka; Andreas Weishaupt; Thomas Wultsch; Claudia Sommer
Human IgG directed against amphiphysin induces anxiety behavior in a rat model after intrathecal passive transfer.
Journal of neural transmission (Vienna, Austria : 1996) 2012;119(8):981-5.
2012: Baohan Pan; Michael Polydefkis; Lawrence P Schramm; Klaus V Toyka; Benedikt Grünewald; Ahmet Höke; JOHN MCDONALD; THIEN NGUYEN; Mohamed H Farah; John W Griffin
The lateral thoracic nerve and the cutaneous maximus muscle--a novel in vivo model system for nerve degeneration and regeneration studies.
Experimental neurology 2012;236(1):6-18.
2012: Philippe Gajdos; Sylvie Chevret; Klaus V Toyka
Intravenous immunoglobulin for myasthenia gravis.
Cochrane database of systematic reviews (Online) 2012;12():CD002277.
2012: Daniel Zeller; Su-Yin Dang; Peter Rieckmann; Klaus V Toyka; David Weise; Joseph Classen
Excitability decreasing central motor plasticity is retained in multiple sclerosis patients.
BMC neurology 2012;12():92.
2011: Grazia Devigili; Karlheinz Reiners; Guido Stoll; Klaus V Toyka; Nurcan Üçeyler; Marcus Beck; Claudia Sommer
Vasculitis-like neuropathy in amyotrophic lateral sclerosis unresponsive to treatment.
Acta neuropathologica 2011;122(3):343-52.
2011: Norman Latov; Marinos Dalakas; Peter Donofrio; Hans-Peter Hartung; Jean-Michel Vallat; Klaus V Toyka
Biomarkers in the diagnosis and therapy of CIDP: Proceedings of the Biomarkers Faculty Meeting; June 8-9, 2010, Athens, Greece.
Journal of the peripheral nervous system : JPNS 2011;16 Suppl 1():1-2.
2011: Daniel Zeller; Su-Yin Dang; Katja Stefan; Armin Biller; Andreas Bartsch; Dorothee Saur; Martin Bendszus; Peter Rieckmann; Klaus V Toyka; Joseph Classen
Functional role of ipsilateral motor areas in multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2011;82(5):578-83.
2011: Christian Geis; Andreas Weishaupt; Benedikt Grünewald; Thomas Wultsch; Andreas Reif; Manfred Gerlach; Ron Dirkx; Michele Solimena; Daniela Perani; Manfred Heckmann; Klaus V Toyka; Franco Folli; Claudia Sommer
Human stiff-person syndrome IgG induces anxious behavior in rats.
PloS one 2011;6(2):e16775.
2010: Christian Geis; Andreas Weishaupt; Stefan Hallermann; Benedikt Grünewald; Carsten Wessig; Thomas Wultsch; Andreas Reif; Nadiya Byts; Marcus Beck; Sibylle Jablonka; Michael K Boettger; Nurcan Üçeyler; Wernher Fouquet; Manfred Gerlach; Hans-Michael Meinck; Anna-Leena Sirén; Stephan J Sigrist; Klaus V Toyka; Manfred Heckmann; Claudia Sommer
Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition.
Brain : a journal of neurology 2010;133(11):3166-80.
2010: Nurcan Üçeyler; Grazia Devigili; Klaus V Toyka; Claudia Sommer
Skin biopsy as an additional diagnostic tool in non-systemic vasculitic neuropathy.
Acta neuropathologica 2010;120(1):109-16.
2010: Nurcan Üçeyler; W Kafke; N Riediger; L He; G Necula; Klaus V Toyka; Claudia Sommer
Elevated proinflammatory cytokine expression in affected skin in small fiber neuropathy.
Neurology 2010;74(22):1806-13.
2010: Juliane Bremer; Frank Baumann; Cinzia Tiberi; Carsten Wessig; Heike Fischer; Petra Schwarz; Andrew D Steele; Klaus V Toyka; Klaus-Armin Nave; Joachim Weis; Adriano Aguzzi
Axonal prion protein is required for peripheral myelin maintenance.
Nature neuroscience 2010;13(3):310-8.
2010: Michael K Boettger; Andreas Weishaupt; Christian Geis; Klaus V Toyka; Claudia Sommer
Mild experimental autoimmune encephalitis as a tool to induce blood-brain barrier dysfunction.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(2):165-9.
2009: Christian Geis; M Beck; S Jablonka; Andreas Weishaupt; Klaus V Toyka; Michael Sendtner; Claudia Sommer
Stiff person syndrome associated anti-amphiphysin antibodies reduce GABA associated [Ca(2+)]i rise in embryonic motoneurons.
Neurobiology of disease 2009;36(1):191-9.
2009: Antonios Bayas; M Stasiolek; Niels Kruse; Klaus V Toyka; Krzysztof Selmaj; Ralf Gold
Altered innate immune response of plasmacytoid dendritic cells in multiple sclerosis.
Clinical and experimental immunology 2009;157(3):332-42.
2009: Yu-Hwa Huang; Alla L Zozulya; Christian Weidenfeller; Imke Metz; Dorothea Buck; Klaus V Toyka; Wolfgang Brück; Heinz Wiendl
Specific central nervous system recruitment of HLA-G(+) regulatory T cells in multiple sclerosis.
Annals of neurology 2009;66(2):171-83.
2008: Ralf Gold; Reinhard Hohlfeld; Klaus V Toyka
Progress in the treatment of myasthenia gravis.
Therapeutic advances in neurological disorders 2008;1(2):36-51.
2008: Maria Schäfers; Sebastian Neukirchen; Klaus V Toyka; Claudia Sommer
Diagnostic value of sural nerve biopsy in patients with suspected Borrelia neuropathy.
Journal of the peripheral nervous system : JPNS 2008;13(1):81-91.
2008: Max-Philipp Stenner; Anne Waschbisch; Dorothea Buck; Sebastian Doerck; Hermann Einsele; Klaus V Toyka; Heinz Wiendl
Effects of natalizumab treatment on Foxp3+ T regulatory cells.
PloS one 2008;3(10):e3319.
2008: Eva Vlcková-Moravcová; Josef Bednarík; Ladislav Dusek; Klaus V Toyka; Claudia Sommer
Diagnostic validity of epidermal nerve fiber densities in painful sensory neuropathies.
Muscle & nerve 2008;37(1):50-60.
2007: Kristian Tersar; Matthias Boentert; Philipp Berger; Sonja Bonneick; Carsten Wessig; Klaus V Toyka; Peter Young; Ueli Suter
Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2.
Human molecular genetics 2007;16(24):2991-3001.
2007: Andrew Chan; De-Hyung Lee; Ralf A Linker; Alexander Mohr; Klaus V Toyka; Ralf Gold
Rescue therapy with anti-CD20 treatment in neuroimmunologic breakthrough disease.
Journal of neurology 2007;254(11):1604-6.
2007: Harald H Hofstetter; Catharina Grau; Mathias Buttmann; Thomas G Forsthuber; Stefanie Gaupp; Klaus V Toyka; Ralf Gold
The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells.
Cytokine 2007;40(1):35-43.
2007: Brigitte Buchwald; Gang Zhang; Angela K Vogt-Eisele; Weiyi Zhang; Raheleh Ahangari; John W Griffin; Hanns Hatt; Klaus V Toyka; Kazim A Sheikh
Anti-ganglioside antibodies alter presynaptic release and calcium influx.
Neurobiology of disease 2007;28(1):113-21.
2007: Christoph M Kosinski; Christiane Schlangen; Frank N Gellerich; Zemfira Z Dr. Gizatullina; Marcus Deschauer; Johannes Schiefer; Anne B Young; G Bernhard Landwehrmeyer; Klaus V Toyka; Bernd Sellhaus; Katrin S Lindenberg
Myopathy as a first symptom of Huntington's disease in a Marathon runner.
Movement disorders : official journal of the Movement Disorder Society 2007;22(11):1637-40.
2007: Nurcan Üçeyler; Jan P Rogausch; Klaus V Toyka; Claudia Sommer
Differential expression of cytokines in painful and painless neuropathies.
Neurology 2007;69(1):42-9.
2007: Marcus Beck; Michael Sendtner; Klaus V Toyka
Novel SOD1 N86K mutation is associated with a severe phenotype in familial ALS.
Muscle & nerve 2007;36(1):111-4.
2007: Philipp Ströbel; Astrid Murumägi; R Klein; M Luster; M Lahti; Kai Krohn; Berthold Schalke; Wilfred Nix; Ralf Gold; Peter Rieckmann; Klaus V Toyka; Christof Burek; Andreas Rosenwald; Hans Konrad Müller-Hermelink; R Pujoll-Borrell; Anthony Meager; Nick Willcox; Pärt Peterson; Alexander Marx
Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1).
The Journal of pathology 2007;211(5):563-71.
2007: Harald H Hofstetter; Klaus V Toyka; Magdalena Tary-Lehmann; Paul V Lehmann
Kinetics and organ distribution of IL-17-producing CD4 cells in proteolipid protein 139-151 peptide-induced experimental autoimmune encephalomyelitis of SJL mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1372-8.
2007: Ines Siglienti; Andrew Chan; Christoph Kleinschnitz; Sebastian Jander; Klaus V Toyka; Ralf Gold; Guido Stoll
Downregulation of transforming growth factor-beta2 facilitates inflammation in the central nervous system by reciprocal astrocyte/microglia interactions.
Journal of neuropathology and experimental neurology 2007;66(1):47-56.
2006: Klaus V Toyka
Ptosis in myasthenia gravis: extended fatigue and recovery bedside test.
Neurology 2006;67(8):1524.
2006: Denise Tischner; Andreas Weishaupt; Jens van den Brandt; Nora Müller; Niklas Beyersdorf; Chi Wang Ip; Klaus V Toyka; Thomas Hünig; Ralf Gold; Thomas Kerkau; Holger M Reichardt
Polyclonal expansion of regulatory T cells interferes with effector cell migration in a model of multiple sclerosis.
Brain : a journal of neurology 2006;129(Pt 10):2635-47.
2006: Christiane Schneider-Gold; Carsten Wessig; Martin Höpker; Bernhard Erdlenbruch; Ralf Gold; Klaus V Toyka
Pregnancy and delivery of a healthy baby in autoimmune Lambert-Eaton myasthenic syndrome.
Journal of neurology 2006;253(9):1236-7.
2006: Harald H Hofstetter; Fred Lühder; Klaus V Toyka; Ralf Gold
IL-17 production by thymocytes upon CD3 stimulation and costimulation with microbial factors.
Cytokine 2006;34(3-4):184-97.
2006: Mariusz Stasiolek; Antonios Bayas; Niels Kruse; Anja Wieczarkowiecz; Klaus V Toyka; Ralf Gold; Krzysztof Selmaj
Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis.
Brain : a journal of neurology 2006;129(Pt 5):1293-305.
2006: Lawrence Wrabetz; Maurizio D'Antonio; Maria Pennuto; Gabriele Dati; Elisa Tinelli; Pietro Fratta; Stefano C Previtali; Daniele Imperiale; Jürgen Zielasek; Klaus V Toyka; Robin L Avila; Daniel A Kirschner; Albee Messing; M Laura Feltri; Angelo Quattrini
Different intracellular pathomechanisms produce diverse Myelin Protein Zero neuropathies in transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(8):2358-68.
2006: Harald H Hofstetter; Klaus V Toyka; Ralf Gold
Permanent effector phenotype of neuroantigen-specific T cells acquired in the central nervous system during experimental allergic encephalomyelitis.
Neuroscience letters 2006;391(3):127-30.
2005: Claudia Sommer; S Koch; M Lammens; A Gabreels-Festen; G Stoll; Klaus V Toyka
Macrophage clustering as a diagnostic marker in sural nerve biopsies of patients with CIDP.
Neurology 2005;65(12):1924-9.
2005: Sonja Bonneick; Matthias Boentert; Philipp Berger; Suzana Atanasoski; Ned Mantei; Carsten Wessig; Klaus V Toyka; Peter Young; Ueli Suter
An animal model for Charcot-Marie-Tooth disease type 4B1.
Human molecular genetics 2005;14(23):3685-95.
2005: Harald H Hofstetter; Saleh M Ibrahim; Dirk Koczan; Niels Kruse; Andreas Weishaupt; Klaus V Toyka; Ralf Gold
Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis.
Cellular immunology 2005;237(2):123-30.
2005: Harald H Hofstetter; R Mössner; K P Lesch; Ralf A Linker; Klaus V Toyka; Ralf Gold
Absence of reuptake of serotonin influences susceptibility to clinical autoimmune disease and neuroantigen-specific interferon-gamma production in mouse EAE.
Clinical and experimental immunology 2005;142(1):39-44.
2005: Michael Reinhardt; Peter Hauff; Ralf A Linker; Andreas Briel; Ralf Gold; Peter Rieckmann; G Becker; Klaus V Toyka; Mathias Mäurer; Michael Schirner
Ultrasound derived imaging and quantification of cell adhesion molecules in experimental autoimmune encephalomyelitis (EAE) by Sensitive Particle Acoustic Quantification (SPAQ).
NeuroImage 2005;27(2):267-78.
2005: Niklas Beyersdorf; Stefanie Gaupp; Karen Balbach; Jens Schmidt; Klaus V Toyka; Chia-Huey Lin; Thomas Hanke; Thomas Hünig; Thomas Kerkau; Ralf Gold
Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 2005;202(3):445-55.
2005: Antje Kroner; Friederike Vogel; Annette Kolb-Mäurer; Niels Kruse; Klaus V Toyka; Bernhard Hemmer; Peter Rieckmann; Mathias Mäurer
Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis.
Journal of neuroimmunology 2005;165(1-2):161-5.
2005: Antje Kroner; Matthias Mehling; Bernhard Hemmer; Peter Rieckmann; Klaus V Toyka; Mathias Mäurer; Heinz Wiendl
A PD-1 polymorphism is associated with disease progression in multiple sclerosis.
Annals of neurology 2005;58(1):50-7.
2005: Stefan Jung; Sabine Zimmer; Edeltraud Lüneberg; Matthias Frosch; Helge Karch; Thomas Korn; Klaus V Toyka
Lipooligosaccharide of Campylobacter jejuni prevents myelin-specific enteral tolerance to autoimmune neuritis--a potential mechanism in Guillain-Barre syndrome?
Neuroscience letters 2005;381(1-2):175-8.
2005: Marcus Beck; Peter Flachenecker; Tim Magnus; Ralf Giess; Karlheinz Reiners; Klaus V Toyka; Markus Naumann
Autonomic dysfunction in ALS: a preliminary study on the effects of intrathecal BDNF.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2005;6(2):100-3.
2005: Ralf A Linker; Evelyn Rott; Harald H Hofstetter; Thomas Hanke; Klaus V Toyka; Ralf Gold
EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses.
Neurobiology of disease 2005;19(1-2):218-28.
2005: Claudia Sommer; Andreas Weishaupt; Jörg Brinkhoff; Lydia Biko; Carsten Wessig; Ralf Gold; Klaus V Toyka
Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin.
Lancet 2005;365(9468):1406-11.
2005: Brigitte Buchwald; Raheleh Ahangari; Andreas Weishaupt; Klaus V Toyka
Presynaptic effects of immunoglobulin G from patients with Lambert-Eaton myasthenic syndrome: their neutralization by intravenous immunoglobulins.
Muscle & nerve 2005;31(4):487-94.
2005: David Bates; Klaus V Toyka; Jerry Wolinsky; Douglas Arnold
Disease management in multiple sclerosis.
European neurology 2005;53(4):203-5.
2005: Martin Berghoff; Mohtashem Samsam; Marcus Müller; Igor Kobsar; Klaus V Toyka; Reinhard Kiefer; Mathias Mäurer; Rudolf Martini
Neuroprotective effect of the immune system in a mouse model of severe dysmyelinating hereditary neuropathy: enhanced axonal degeneration following disruption of the RAG-1 gene.
Molecular and cellular neurosciences 2005;28(1):118-27.
2005: Andrew Chan; Franz X Weilbach; Klaus V Toyka; Ralf Gold
Mitoxantrone induces cell death in peripheral blood leucocytes of multiple sclerosis patients.
Clinical and experimental immunology 2005;139(1):152-8.
2004: Christiane Schneider-Gold; Meinrad Beer; Herbert Köstler; Stefan Buchner; Jörn Sandstede; Dietbert Hahn; Klaus V Toyka
Cardiac and skeletal muscle involvement in myotonic dystrophy type 2 (DM2): a quantitative 31P-MRS and MRI study.
Muscle & nerve 2004;30(5):636-44.
2004: Thomas Korn; Tim Magnus; Klaus V Toyka; Stefan Jung
Modulation of effector cell functions in experimental autoimmune encephalomyelitis by leflunomide--mechanisms independent of pyrimidine depletion.
Journal of leukocyte biology 2004;76(5):950-60.
2004: Martin Bendszus; Martin Koltzenburg; Andreas Joachim Bartsch; Roland Goldbrunner; Thomas Günthner-Lengsfeld; Franz X Weilbach; Klaus Roosen; Klaus V Toyka; Laszlo Solymosi
Heparin and air filters reduce embolic events caused by intra-arterial cerebral angiography: a prospective, randomized trial.
Circulation 2004;110(15):2210-5.
2004: Rudolf Martini; Klaus V Toyka
Immune-mediated components of hereditary demyelinating neuropathies: lessons from animal models and patients.
Lancet neurology 2004;3(8):457-65.
2004: Antje Kroner; Mathias Mäurer; Silke Loserth; C Kleinschnitz; Bernhard Hemmer; Berit Rosche; Klaus V Toyka; Peter Rieckmann
Analysis of the monocyte chemoattractant protein 1 -2518 promoter polymorphism in patients with multiple sclerosis.
Tissue antigens 2004;64(1):70-3.
2004: Mathias Mäurer; Guido Stoll; Klaus V Toyka
Multifocal motor neuropathy presenting as chronic progressive proximal leg weakness.
Neuromuscular disorders : NMD 2004;14(6):380-2.
2004: Philipp Ströbel; Andrea Bauer; Bernhard Puppe; Til Kraushaar; Axel Krein; Klaus V Toyka; Ralf Gold; Michael Semik; Reinhard Kiefer; Wilfred Nix; Berthold Schalke; Hans Konrad Müller-Hermelink; Alexander Marx
Tumor recurrence and survival in patients treated for thymomas and thymic squamous cell carcinomas: a retrospective analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(8):1501-9.
2004: Peter Flachenecker; Irene Bihler; F Weber; M Gottschalk; Klaus V Toyka; Peter Rieckmann
Cytokine mRNA expression in patients with multiple sclerosis and fatigue.
Multiple sclerosis (Houndmills, Basingstoke, England) 2004;10(2):165-9.
2004: Guido Stoll; Carmen Wesemeier; Ralf Gold; Laszlo Solymosi; Klaus V Toyka; Martin Bendszus
In vivo monitoring of macrophage infiltration in experimental autoimmune neuritis by magnetic resonance imaging.
Journal of neuroimmunology 2004;149(1-2):142-6.
2004: Kai G Kahl; Harald Schmidt; Stefan Jung; Paula Sherman; Klaus V Toyka; Jürgen Zielasek
Experimental autoimmune encephalomyelitis in mice with a targeted deletion of the inducible nitric oxide synthase gene: increased T-helper 1 response.
Neuroscience letters 2004;358(1):58-62.
2004: Stefan Jung; Ines Siglienti; Oliver Grauer; Tim Magnus; Guglielmo Scarlato; Klaus V Toyka
Induction of IL-10 in rat peritoneal macrophages and dendritic cells by glatiramer acetate.
Journal of neuroimmunology 2004;148(1-2):63-73.
2004: Stefan Jung; Stefanie Gaupp; Thomas Korn; Gabriele Köllner; Hans-Peter Hartung; Klaus V Toyka
Biphasic form of experimental autoimmune neuritis in dark Agouti rats and its oral therapy by antigen-specific tolerization.
Journal of neuroscience research 2004;75(4):524-35.
2004: Benedikt Schoser; Christiane Schneider-Gold; Wolfram Kress; Hans-Hilmar Goebel; Peter Reilich; Manuela C Koch; Dieter Pongratz; Klaus V Toyka; Hanns Lochmüller; Kenneth Ricker
Muscle pathology in 57 patients with myotonic dystrophy type 2.
Muscle & nerve 2004;29(2):275-81.
2004: Lucian Visan; Ioana A Visan; Andreas Weishaupt; Harald H Hofstetter; Klaus V Toyka; Thomas Hünig; Ralf Gold
Tolerance induction by intrathymic expression of P0.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1364-70.
2004: Franz X Weilbach; Andrew Chan; Klaus V Toyka; Ralf Gold
The cardioprotector dexrazoxane augments therapeutic efficacy of mitoxantrone in experimental autoimmune encephalomyelitis.
Clinical and experimental immunology 2004;135(1):49-55.
2003: Christoph Kleinschnitz; Martin Bendszus; Marco Frank; Laszlo Solymosi; Klaus V Toyka; Guido Stoll
In vivo monitoring of macrophage infiltration in experimental ischemic brain lesions by magnetic resonance imaging.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(11):1356-61.
2003: Peter Flachenecker; A Rufer; I Bihler; C Hippel; Karlheinz Reiners; Klaus V Toyka; J Kesselring
Fatigue in MS is related to sympathetic vasomotor dysfunction.
Neurology 2003;61(6):851-3.
2003: Jerry Wolinsky; Klaus V Toyka; Ludwig Kappos; Sidney E Grossberg
Interferon-beta antibodies: implications for the treatment of MS.
Lancet neurology 2003;2(9):528.
2003: Andrew Chan; Rosanne Seguin; Tim Magnus; Christina Papadimitriou; Klaus V Toyka; Jack P Antel; Ralf Gold
Phagocytosis of apoptotic inflammatory cells by microglia and its therapeutic implications: termination of CNS autoimmune inflammation and modulation by interferon-beta.
Glia 2003;43(3):231-42.
2003: Jens Schmidt; Josbert M Metselaar; Marca H M Wauben; Klaus V Toyka; Gert Storm; Ralf Gold
Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis.
Brain : a journal of neurology 2003;126(Pt 8):1895-904.
2003: Carsten Wessig; R Klein; M F Schneider; Klaus V Toyka; Markus Naumann; Claudia Sommer
Neuropathology and binding studies in anti-amphiphysin-associated stiff-person syndrome.
Neurology 2003;61(2):195-8.
2003: Kai G Kahl; Jürgen Zielasek; L Otto Uttenthal; José Rodrigo; Klaus V Toyka; Harald Schmidt
Protective role of the cytokine-inducible isoform of nitric oxide synthase induction and nitrosative stress in experimental autoimmune encephalomyelitis of the DA rat.
Journal of neuroscience research 2003;73(2):198-205.
2003: Jens Schmidt; Karin Elflein; Martina Stienekemeier; Marta Rodriguez-Palmero; Christiane Schneider; Klaus V Toyka; Ralf Gold; Thomas Hünig
Treatment and prevention of experimental autoimmune neuritis with superagonistic CD28-specific monoclonal antibodies.
Journal of neuroimmunology 2003;140(1-2):143-52.
2003: Klaus V Toyka; Christiane Schneider-Gold
Oculomotor signs in Lambert-Eaton myasthenic syndrome-coincidence with myasthenia gravis.
Annals of neurology 2003;54(1):135-6; author reply 136-7.
2003: Thomas Korn; Klaus-Dieter Fischer; Irute Girkontaite; Gabriele Köllner; Klaus V Toyka; Stefan Jung
Vav1-deficient mice are resistant to MOG-induced experimental autoimmune encephalomyelitis due to impaired antigen priming.
Journal of neuroimmunology 2003;139(1-2):17-26.
2003: Peter Flachenecker; Christiane Schneider; Simone Cursiefen; Kenneth Ricker; Klaus V Toyka; Karlheinz Reiners
Assessment of cardiovascular autonomic function in myotonic dystrophy type 2 (DM2/PROMM).
Neuromuscular disorders : NMD 2003;13(4):289-93.
2003: Klaus V Toyka; Ralf Gold
The pathogenesis of CIDP: rationale for treatment with immunomodulatory agents.
Neurology 2003;60(8 Suppl 3):S2-7.
2003: Mohtashem Samsam; Weiqian Mi; Carsten Wessig; Jürgen Zielasek; Klaus V Toyka; Michael P Coleman; Rudolf Martini
The Wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(7):2833-9.
2003: Klaus Krampfl; Bahram Mohammadi; Brigitte Buchwald; Klaus Jahn; Reinhard Dengler; Klaus V Toyka; Johannes Bufler
IgG from patients with Guillain-Barré syndrome interact with nicotinic acetylcholine receptor channels.
Muscle & nerve 2003;27(4):435-41.
2003: Igor Kobsar; Martin Berghoff; Mohtashem Samsam; Carsten Wessig; Mathias Mäurer; Klaus V Toyka; Rudolf Martini
Preserved myelin integrity and reduced axonopathy in connexin32-deficient mice lacking the recombination activating gene-1.
Brain : a journal of neurology 2003;126(Pt 4):804-13.
2003: Christiane Schneider-Gold; M Beck; Carsten Wessig; Annette George; H Kele; Karlheinz Reiners; Klaus V Toyka
Creatine monohydrate in DM2/PROMM: a double-blind placebo-controlled clinical study. Proximal myotonic myopathy.
Neurology 2003;60(3):500-2.
2003: Andrew Chan; Christina Papadimitriou; Wolfgang Graf; Klaus V Toyka; Ralf Gold
Effects of polyclonal immunoglobulins and other immunomodulatory agents on microglial phagocytosis of apoptotic inflammatory T-cells.
Journal of neuroimmunology 2003;135(1-2):161-5.
2003: Antonios Bayas; Niels Kruse; NF Moriabadi; F Weber; Vera Hummel; G Wohleben; Ralf Gold; Klaus V Toyka; Peter Rieckmann
Modulation of cytokine mRNA expression by brain-derived neurotrophic factor and nerve growth factor in human immune cells.
Neuroscience letters 2003;335(3):155-8.
2003: Ralf Gold; Marinos C Dalakas; Klaus V Toyka
Immunotherapy in autoimmune neuromuscular disorders.
Lancet neurology 2003;2(1):22-32.
2003: Wolfgang Müllges; Dorothea Franke; Wilko Reents; Jörg Babin-Ebell; Klaus V Toyka
Reduced rate of microembolism by optimized aortic cannula position does not influence early postoperative cognitive performance in CABG patients.
Cerebrovascular diseases (Basel, Switzerland) 2003;15(3):192-8.
2002: Brigitte Buchwald; Raheleh Ahangari; Klaus V Toyka
Differential blocking effects of the monoclonal anti-GQ1b IgM antibody and alpha-latrotoxin in the absence of complement at the mouse neuromuscular junction.
Neuroscience letters 2002;334(1):25-8.
2002: Mathias Mäurer; Klaus V Toyka; Ralf Gold
Cellular immunity in inflammatory autoimmune neuropathies.
Revue neurologique 2002;158(12 Pt 2):S7-15.
2002: Peter Flachenecker; Tania Kümpfel; Boris-A Kallmann; M Gottschalk; Oliver Grauer; Peter Rieckmann; Claudia Trenkwalder; Klaus V Toyka
Fatigue in multiple sclerosis: a comparison of different rating scales and correlation to clinical parameters.
Multiple sclerosis (Houndmills, Basingstoke, England) 2002;8(6):523-6.
2002: Klaus V Toyka; Bettina Müller; Heinz Reichmann
"Atraumatic" Sprotte needle reduces the incidence of post-lumbar puncture headaches.
Neurology 2002;59(7):1120; author reply 1120-1.
2002: Giancarlo Comi; Luisa Roveri; Anthony V Swan; Hugh J Willison; Martin Bojar; Isabel Illa; Clementine Karageorgiou; Eduardo Nobile-Orazio; P Y K Van Den Bergh; Tony Swan; Rhidian Hughes; Jaques Aubry; Nicole Baumann; R D M Hadden; M P T Lunn; Martin Knapp; Jean-Marc Léger; Pierre Bouche; Radim Mazanec; Nicoletta Meucci; Frans van der Meché; Klaus V Toyka
A randomised controlled trial of intravenous immunoglobulin in IgM paraprotein associated demyelinating neuropathy.
Journal of neurology 2002;249(10):1370-7.
2002: Andreas Weishaupt; Tanja Kuhlmann; Lisa M Schönrock; Klaus V Toyka; Wolfgang Brück; Ralf Gold
Effects of intravenous immunoglobulins on T cell and oligodendrocyte apoptosis in high-dose antigen therapy in experimental autoimmune encephalomyelitis.
Acta neuropathologica 2002;104(4):385-90.
2002: Wolfgang Müllges; Jörg Babin-Ebell; Wilko Reents; Klaus V Toyka
Cognitive performance after coronary artery bypass grafting: a follow-up study.
Neurology 2002;59(5):741-3.
2002: Tim Magnus; Andrew Chan; Ralf A Linker; Klaus V Toyka; Ralf Gold
Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: implications for the role of glial cells in the inflamed central nervous system.
Journal of neuropathology and experimental neurology 2002;61(9):760-6.
2002: Tim Magnus; Andrew Chan; John Savill; Klaus V Toyka; Ralf Gold
Phagocytotic removal of apoptotic, inflammatory lymphocytes in the central nervous system by microglia and its functional implications.
Journal of neuroimmunology 2002;130(1-2):1-9.
2002: Kai G Kahl; Niels Kruse; Klaus V Toyka; Peter Rieckmann
Serial analysis of cytokine mRNA profiles in whole blood samples from patients with early multiple sclerosis.
Journal of the neurological sciences 2002;200(1-2):53-5.
2002: Claudia Sommer; Thies Lindenlaub; Detlef Zillikens; Klaus V Toyka; Markus Naumann
Selective loss of cholinergic sudomotor fibers causes anhidrosis in Ross syndrome.
Annals of neurology 2002;52(2):247-50.
2002: Peter Flachenecker; Stefan Jung; Peter Rieckmann; Klaus V Toyka
sICAM-1 is not a marker for disease activity in the relapse-free interval of multiple sclerosis--a cross-sectional pilot study.
Journal of neurology 2002;249(8):1001-3.
2002: Martin Offenhäusser; Alexandra S Herr; Jörg Hartkamp; Marca H M Wauben; Tim Magnus; Oliver Grauer; Silvia Seubert; Andreas Weishaupt; Klaus V Toyka; Ralf Gold; Jakob Troppmair
Truncation of the neuritogenic peptide bP2(60-70) results in the generation of altered peptide ligands with the potential to interfere with T cell activation.
Journal of neuroimmunology 2002;129(1-2):97-105.
2002: Maria Schäfers; Christine Schmidt; Carola Vogel; Klaus V Toyka; Claudia Sommer
Tumor necrosis factor-alpha (TNF) regulates the expression of ICAM-1 predominantly through TNF receptor 1 after chronic constriction injury of mouse sciatic nerve.
Acta neuropathologica 2002;104(2):197-205.
2002: Antonios Bayas; Vera Hummel; Boris-A Kallmann; Christoph Karch; Klaus V Toyka; Peter Rieckmann
Human cerebral endothelial cells are a potential source for bioactive BDNF.
Cytokine 2002;19(2):55-8.
2002: Marcus Beck; Ralf Giess; Tim Magnus; Imke Puls; Karlheinz Reiners; Klaus V Toyka; Markus Naumann
Progressive sudomotor dysfunction in amyotrophic lateral sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2002;73(1):68-70.
2002: Brigitte Buchwald; Raheleh Ahangari; Andreas Weishaupt; Klaus V Toyka
Intravenous immunoglobulins neutralize blocking antibodies in Guillain-Barré syndrome.
Annals of neurology 2002;51(6):673-80.
2002: Ralf A Linker; Mathias Mäurer; Stefanie Gaupp; Rudolf Martini; Bettina Holtmann; Ralf Giess; Peter Rieckmann; Hans Lassmann; Klaus V Toyka; Michael Sendtner; Ralf Gold
CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation.
Nature medicine 2002;8(6):620-4.
2002: Mathias Mäurer; Klaus V Toyka; Ralf Gold
Immune mechanisms in acquired demyelinating neuropathies: lessons from animal models.
Neuromuscular disorders : NMD 2002;12(4):405-14.
2002: Meinrad Beer; Christiane Schneider; Herbert Köstler; Stefan Buchner; Jörn Sandstede; Klaus V Toyka; Dietbert Hahn
Quantitative analysis of energy metabolism in human muscle using SLOOP 31P-MR-spectroscopy.
RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 2002;174(5):573-8.
2002: Tim Magnus; Marcus Beck; Ralf Giess; Imke Puls; Markus Naumann; Klaus V Toyka
Disease progression in amyotrophic lateral sclerosis: predictors of survival.
Muscle & nerve 2002;25(5):709-14.
2002: Ralf Giess; Bettina Holtmann; Massimiliano Braga; Tiemo Grimm; Bertram Müller-Myhsok; Klaus V Toyka; Michael Sendtner
Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene.
American journal of human genetics 2002;70(5):1277-86.
2002: Klaus V Toyka; Jürgen Zielasek; Guido Stoll
Myelin-derived glycolipids and animal models of Guillain-Barré syndrome.
Annals of neurology 2002;51(4):532; author reply 532-3.
2002: Bernd C Kieseier; Marie Tani; Don J Mahad; Nobuyuki Oka; Ho W Tony; Nicola Woodroofe; John W Griffin; Klaus V Toyka; Richard M Ransohoff; Hans-Peter Hartung
Chemokines and chemokine receptors in inflammatory demyelinating neuropathies: a central role for IP-10.
Brain : a journal of neurology 2002;125(Pt 4):823-34.
2002: Ralf Giess; Mathias Mäurer; Ralf A Linker; Ralf Gold; Monika Warmuth-Metz; Klaus V Toyka; Michael Sendtner; Peter Rieckmann
Association of a null mutation in the CNTF gene with early onset of multiple sclerosis.
Archives of neurology 2002;59(3):407-9.
2002: Hugh J Willison; Guido Stoll; Klaus V Toyka; Thomas Berger; Hans-Peter Hartung
Autoimmunity and inflammation in the peripheral nervous system.
Trends in neurosciences 2002;25(3):127-9.
2002: Christiane Schneider; Ralf Gold; M Schäfers; Klaus V Toyka
Mycophenolate mofetil in the therapy of polymyositis associated with a polyautoimmune syndrome.
Muscle & nerve 2002;25(2):286-8.
2002: VI Leussink; U K Zettl; Sebastian Jander; R Blake Pepinsky; Roy R Lobb; Guido Stoll; Klaus V Toyka; Ralf Gold
Blockade of signaling via the very late antigen (VLA-4) and its counterligand vascular cell adhesion molecule-1 (VCAM-1) causes increased T cell apoptosis in experimental autoimmune neuritis.
Acta neuropathologica 2002;103(2):131-6.
2002: Franz X Weilbach; Klaus V Toyka
Does Down's syndrome protect against multiple sclerosis?
European neurology 2002;47(1):52-5.
2001: Martina Stienekemeier; Kirsten Falk; Olaf Rötzschke; Andreas Weishaupt; Christiane Schneider; Klaus V Toyka; Ralf Gold; Jack L Strominger
Vaccination, prevention, and treatment of experimental autoimmune neuritis (EAN) by an oligomerized T cell epitope.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13872-7.
2001: Tim Magnus; Andrew Chan; Oliver Grauer; Klaus V Toyka; Ralf Gold
Microglial phagocytosis of apoptotic inflammatory T cells leads to down-regulation of microglial immune activation.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5004-10.
2001: Peter Flachenecker; Karlheinz Reiners; M Krauser; A Wolf; Klaus V Toyka
Autonomic dysfunction in multiple sclerosis is related to disease activity and progression of disability.
Multiple sclerosis (Houndmills, Basingstoke, England) 2001;7(5):327-34.
2001: Claudia Sommer; Thies Lindenlaub; P Teuteberg; Maria Schäfers; Thomas Hartung; Klaus V Toyka
Anti-TNF-neutralizing antibodies reduce pain-related behavior in two different mouse models of painful mononeuropathy.
Brain research 2001;913(1):86-9.
2001: Thomas Korn; Klaus V Toyka; Hans-Peter Hartung; Stefan Jung
Suppression of experimental autoimmune neuritis by leflunomide.
Brain : a journal of neurology 2001;124(Pt 9):1791-802.
2001: Christiane Schneider; Karlheinz Reiners; Klaus V Toyka
[Myotonic dystrophy (DM/Curschmann-Steinert disease) and proximal myotonic myopathy (PROMM/Ricker syndrome). Myotonic muscle diseases with multisystemic manifestations].
Der Nervenarzt 2001;72(8):618-24.
2001: Peter Flachenecker; Klaus V Toyka; Karlheinz Reiners
[Cardiac arrhythmias in Guillain-Barre syndrome. An overview of the diagnosis of a rare but potentially life-threatening complication].
Der Nervenarzt 2001;72(8):610-7.
2001: Oliver Grauer; M Offenhäusser; Jens Schmidt; Klaus V Toyka; Ralf Gold
[Glucocorticosteroid therapy in optic neuritis and multiple sclerosis. Evidence from clinical studies and practical recommendations].
Der Nervenarzt 2001;72(8):577-89.
2001: Ralf Gold; F Buttgereit; Klaus V Toyka
Mechanism of action of glucocorticosteroid hormones: possible implications for therapy of neuroimmunological disorders.
Journal of neuroimmunology 2001;117(1-2):1-8.
2001: Andreas Weishaupt; Lisa M Schönrock; Martina Stienekemeier; Klaus V Toyka; Ralf Gold
Glucocorticosteroids modulate antigen-induced T cell apoptosis in experimental autoimmune neuritis and cause T cell proliferation in situ.
Acta neuropathologica 2001;102(1):75-82.
2001: Jens Schmidt; S Stürzebecher; Klaus V Toyka; Ralf Gold
Interferon-beta treatment of experimental autoimmune encephalomyelitis leads to rapid nonapoptotic termination of T cell infiltration.
Journal of neuroscience research 2001;65(1):59-67.
2001: Andreas Weishaupt; Wolfgang Brück; Thomas Hartung; Klaus V Toyka; Ralf Gold
Schwann cell apoptosis in experimental autoimmune neuritis of the Lewis rat and the functional role of tumor necrosis factor-alpha.
Neuroscience letters 2001;306(1-2):77-80.
2001: Claudia Sommer; Maria Schäfers; Martin Marziniak; Klaus V Toyka
Etanercept reduces hyperalgesia in experimental painful neuropathy.
Journal of the peripheral nervous system : JPNS 2001;6(2):67-72.
2001: Mathias Mäurer; Christoph D Schmid; F Bootz; Jürgen Zielasek; Klaus V Toyka; S Oehen; Rudolf Martini
Bone marrow transfer from wild-type mice reverts the beneficial effect of genetically mediated immune deficiency in myelin mutants.
Molecular and cellular neurosciences 2001;17(6):1094-101.
2001: Meinrad Beer; Jörn Sandstede; Franz X Weilbach; Matthias Spindler; Stefan Buchner; A Krug; Herbert Köstler; Thomas Pabst; Werner Kenn; Wilfried Landschütz; Markus von Kienlin; Klaus V Toyka; Georg Ertl; Ralf Gold; Dietbert Hahn
Cardiac metabolism and function in patients with multiple sclerosis: a combined 31P-MR-spectroscopy and MRI study.
RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 2001;173(5):399-404.
2001: Stefan Jung; Stefanie Gaupp; Hans-Peter Hartung; Klaus V Toyka
Oral tolerance in experimental autoimmune neuritis (EAN) of the Lewis rat. II. Adjuvant effects and bystander suppression in P2 peptide-induced EAN.
Journal of neuroimmunology 2001;116(1):21-8.
2001: NF Moriabadi; Stefan Niewiesk; Niels Kruse; S Jung; Benedikt Weissbrich; V ter Meulen; Klaus V Toyka; Peter Rieckmann
Influenza vaccination in MS: absence of T-cell response against white matter proteins.
Neurology 2001;56(7):938-43.
2001: Vera Hummel; Boris-A Kallmann; Sven Wagner; T Füller; Antonios Bayas; Jörg-Christian Tonn; E N Benveniste; Klaus V Toyka; Peter Rieckmann
Production of MMPs in human cerebral endothelial cells and their role in shedding adhesion molecules.
Journal of neuropathology and experimental neurology 2001;60(4):320-7.
2001: R D M Hadden; H Karch; H P Hartung; Jürgen Zielasek; B Weissbrich; J Schubert; Andreas Weishaupt; David R Cornblath; Anthony V Swan; Richard AC Hughes; Klaus V Toyka
Preceding infections, immune factors, and outcome in Guillain-Barré syndrome.
Neurology 2001;56(6):758-65.
2001: Carsten Wessig; Brigitte Buchwald; Klaus V Toyka; Rudolf Martini
Miller Fisher syndrome: immunofluorescence and immunoelectron microscopic localization of IgG at the mouse neuromuscular junction.
Acta neuropathologica 2001;101(3):239-44.
2001: M Mäurer; Ralf Gold; Klaus V Toyka; P Rieckmann
[Treatment of relapsing-remitting multiple sclerosis with recombinant interferon-beta preparations].
Der Nervenarzt 2001;72(2):108-16.
2001: Bernd C Kieseier; C Schneider; John M Clements; AJ Gearing; R Gold; Klaus V Toyka; Hans-Peter Hartung
Expression of specific matrix metalloproteinases in inflammatory myopathies.
Brain : a journal of neurology 2001;124(Pt 2):341-51.
2001: Stefano Carenini; Mathias Mäurer; A Werner; H Blazyca; Klaus V Toyka; Christoph D Schmid; G Raivich; Rudolf Martini
The role of macrophages in demyelinating peripheral nervous system of mice heterozygously deficient in p0.
The Journal of cell biology 2001;152(2):301-8.
2001: Brigitte Buchwald; Johannes Bufler; Marinella Carpo; Fedor Heidenreich; R Pitz; Josef Dudel; Eduardo Nobile-Orazio; Klaus V Toyka
Combined pre- and postsynaptic action of IgG antibodies in Miller Fisher syndrome.
Neurology 2001;56(1):67-74.
2001: Christiane Schneider; Ralf Gold; K Reiners; Klaus V Toyka
Mycophenolate mofetil in the therapy of severe myasthenia gravis.
European neurology 2001;46(2):79-82.
2001: VI Leussink; S Jung; U Merschdorf; Klaus V Toyka; Ralf Gold
High-dose methylprednisolone therapy in multiple sclerosis induces apoptosis in peripheral blood leukocytes.
Archives of neurology 2001;58(1):91-7.
2001: Niels Kruse; NF Moriabadi; Klaus V Toyka; Peter Rieckmann
Characterization of early immunological responses in primary cultures of differentially activated human peripheral mononuclear cells.
Journal of immunological methods 2001;247(1-2):131-9.
2000: Andreas Weishaupt; Sebastian Jander; Wolfgang Brück; Tanja Kuhlmann; Martina Stienekemeier; Thomas Hartung; Klaus V Toyka; Guido Stoll; Ralf Gold
Molecular mechanisms of high-dose antigen therapy in experimental autoimmune encephalomyelitis: rapid induction of Th1-type cytokines and inducible nitric oxide synthase.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7157-63.
2000: A George; Martin Marziniak; Maria Schäfers; Klaus V Toyka; Claudia Sommer
Thalidomide treatment in chronic constrictive neuropathy decreases endoneurial tumor necrosis factor-alpha, increases interleukin-10 and has long-term effects on spinal cord dorsal horn met-enkephalin.
Pain 2000;88(3):267-75.
2000: Bernd C Kieseier; K Krivacic; S Jung; Heidrun Pischel; Klaus V Toyka; Richard M Ransohoff; Hans-Peter Hartung
Sequential expression of chemokines in experimental autoimmune neuritis.
Journal of neuroimmunology 2000;110(1-2):121-9.
2000: Wolfram Kress; B Mueller-Myhsok; Kenneth Ricker; Christiane Schneider; Manuela C Koch; Klaus V Toyka; CR Mueller; Tiemo Grimm
Proof of genetic heterogeneity in the proximal myotonic myopathy syndrome (PROMM) and its relationship to myotonic dystrophy type 2 (DM2).
Neuromuscular disorders : NMD 2000;10(7):478-80.
2000: A Niehaus; J Shi; M Grzenkowski; M Diers-Fenger; Juan J Archelos; H P Hartung; Klaus V Toyka; W Brück; Jacqueline Trotter
Patients with active relapsing-remitting multiple sclerosis synthesize antibodies recognizing oligodendrocyte progenitor cell surface protein: implications for remyelination.
Annals of neurology 2000;48(3):362-71.
2000: I S J Merkies; P I M Schmitz; J P A Samijn; F G Meché; Klaus V Toyka; Pieter A Van Doorn
Assessing grip strength in healthy individuals and patients with immune-mediated polyneuropathies.
Muscle & nerve 2000;23(9):1393-401.
2000: Christiane Schneider; A Ziegler; Kenneth Ricker; Tiemo Grimm; Wolfram Kress; C D Reimers; Hans-Michael Meinck; Karlheinz Reiners; Klaus V Toyka
Proximal myotonic myopathy: evidence for anticipation in families with linkage to chromosome 3q.
Neurology 2000;55(3):383-8.
2000: Christiane Schneider; Y Matsumoto; K Kohyama; Klaus V Toyka; Hans-Peter Hartung; Ralf Gold
Experimental autoimmune myositis in the lewis rat: lack of spontaneous T-cell apoptosis and therapeutic response to glucocorticosteroid application.
Journal of neuroimmunology 2000;107(1):83-7.
2000: Jens Schmidt; Ralf Gold; Lisa M Schönrock; U K Zettl; Hans-Peter Hartung; Klaus V Toyka
T-cell apoptosis in situ in experimental autoimmune encephalomyelitis following methylprednisolone pulse therapy.
Brain : a journal of neurology 2000;123 ( Pt 7)():1431-41.
2000: Ralf Giess; Markus Naumann; E Werner; Randolf Riemann; Marcus Beck; Imke Puls; Christoph Reiners; Klaus V Toyka
Injections of botulinum toxin A into the salivary glands improve sialorrhoea in amyotrophic lateral sclerosis.
Journal of neurology, neurosurgery, and psychiatry 2000;69(1):121-3.
2000: G Ochs; Richard D Penn; M York; Ralf Giess; Marcus Beck; Jörg-Christian Tonn; J Haigh; E Malta; M Traub; Michael Sendtner; Klaus V Toyka
A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 2000;1(3):201-6.
2000: Gisela Wohlleben; Saleh M Ibrahim; J Schmidt; Klaus V Toyka; Hans-Peter Hartung; Ralf Gold
Regulation of Fas and FasL expression on rat Schwann cells.
Glia 2000;30(4):373-81.
2000: Andreas Weishaupt; Ralf Gold; Thomas Hartung; Stefanie Gaupp; A Wendel; Wolfgang Brück; Klaus V Toyka
Role of TNF-alpha in high-dose antigen therapy in experimental autoimmune neuritis: inhibition of TNF-alpha by neutralizing antibodies reduces T-cell apoptosis and prevents liver necrosis.
Journal of neuropathology and experimental neurology 2000;59(5):368-76.
2000: Jürgen Zielasek; Rudolf Martini; U Suter; Klaus V Toyka
Neuromyotonia in mice with hereditary myelinopathies.
Muscle & nerve 2000;23(5):696-701.
2000: Boris-A Kallmann; Vera Hummel; Thies Lindenlaub; Klemens Ruprecht; Klaus V Toyka; Peter Rieckmann
Cytokine-induced modulation of cellular adhesion to human cerebral endothelial cells is mediated by soluble vascular cell adhesion molecule-1.
Brain : a journal of neurology 2000;123 ( Pt 4)():687-97.
2000: Ralf Giess; M Beck; R Goetz; Roger M Nitsch; Klaus V Toyka; Michael Sendtner
Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis.
Neurology 2000;54(4):1003-5.
2000: Ralf Gold; Hans-Peter Hartung; Klaus V Toyka
Animal models for autoimmune demyelinating disorders of the nervous system.
Molecular medicine today 2000;6(2):88-91.
2000: Niels Kruse; M Greif; NF Moriabadi; L Marx; Klaus V Toyka; Peter Rieckmann
Variations in cytokine mRNA expression during normal human pregnancy.
Clinical and experimental immunology 2000;119(2):317-22.
2000: Christoph D Schmid; Martina Stienekemeier; S Oehen; F Bootz; Jürgen Zielasek; Ralf Gold; Klaus V Toyka; M Schachner; Rudolf Martini
Immune deficiency in mouse models for inherited peripheral neuropathies leads to improved myelin maintenance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(2):729-35.
2000: Simone Cursiefen; Peter Flachenecker; Klaus V Toyka; Peter Rieckmann
Escalating immunotherapy with mitoxantrone in patients with very active relapsing-remitting or progressive multiple sclerosis.
European neurology 2000;43(3):186-7.
1999: Imke Puls; Marcus Beck; Ralf Giess; Tim Magnus; G Ochs; Klaus V Toyka
[Clenbuterol in amyotrophic lateral sclerosis. No indication for a positive effect].
Der Nervenarzt 1999;70(12):1112-5.
1999: Ralf Gold; M Oelschläger; R Blake Pepinsky; Claudia Sommer; Hans-Peter Hartung; Klaus V Toyka
Increased lipocortin-1 (annexin-1) expression in the sciatic nerve of Lewis rats with experimental autoimmune neuritis.
Acta neuropathologica 1999;98(6):583-9.
1999: Imke Puls; K Hauck; K Demuth; Anja Horowski; Mira Schliesser; P Dörfler; Peter Scheel; Klaus V Toyka; Karlheinz Reiners; Martin Schöning; Georg Becker
Diagnostic impact of cerebral transit time in the identification of microangiopathy in dementia: A transcranial ultrasound study.
Stroke; a journal of cerebral circulation 1999;30(11):2291-5.
1999: Bettina Holtmann; Jürgen Zielasek; Klaus V Toyka; Michael Sendtner
Comparative analysis of motoneuron loss and functional deficits in PMN mice: implications for human motoneuron disease.
Journal of the neurological sciences 1999;169(1-2):140-7.
1999: Andrew Chan; Ralf Gold; G Giegerich; Thomas Herrmann; Stefan Jung; Klaus V Toyka; Hans-Peter Hartung
Usage of Vbeta3.3 T-cell receptor by myelin basic protein-specific encephalitogenic T-cell lines in the Lewis rat.
Journal of neuroscience research 1999;58(2):214-25.
1999: Brigitte Buchwald; marc de baets; Gert-Jan Luijckx; Klaus V Toyka
Neonatal Guillain-Barré syndrome: blocking antibodies transmitted from mother to child.
Neurology 1999;53(6):1246-53.
1999: Jürgen Zielasek; Klaus V Toyka
Nerve conduction abnormalities and neuromyotonia in genetically engineered mouse models of human hereditary neuropathies.
Annals of the New York Academy of Sciences 1999;883():310-20.
1999: Wolfgang Müllges; D Berg; J Jörg Babin-Ebell; Klaus V Toyka; Olaf Elert
Cerebral microembolus generation in different extracorporeal circulation systems.
Cerebrovascular diseases (Basel, Switzerland) 1999;9(5):265-9.
1999: Marcus Beck; Ralf Giess; W Würffel; Tim Magnus; G Ochs; Klaus V Toyka
Comparison of maximal voluntary isometric contraction and Drachman's hand-held dynamometry in evaluating patients with amyotrophic lateral sclerosis.
Muscle & nerve 1999;22(9):1265-70.
1999: Simone Cursiefen; Peter Flachenecker; Peter Rieckmann; Klaus V Toyka
[Mitoxantrone (Novantron) in therapy of severe multiple sclerosis. A retrospective study of 15 patients].
Der Nervenarzt 1999;70(8):723-31.
1999: Markus Naumann; W H Jost; Klaus V Toyka
Botulinum toxin in the treatment of neurological disorders of the autonomic nervous system.
Archives of neurology 1999;56(8):914-6.
1999: Claudia Sommer; S Petrausch; Thies Lindenlaub; Klaus V Toyka
Neutralizing antibodies to interleukin 1-receptor reduce pain associated behavior in mice with experimental neuropathy.
Neuroscience letters 1999;270(1):25-8.
1999: Wolfgang Müllges; D Berg; Klaus V Toyka
Bilateral cerebral emboli monitoring during extracorporeal circulation.
Ultrasound in medicine & biology 1999;25(5):755-8.
1999: Peter Flachenecker; M Janka; Roland Goldbrunner; Klaus V Toyka
Clinical outcome of sural nerve biopsy: a retrospective study.
Journal of neurology 1999;246(2):93-6.
1999: P Rieckmann; Klaus V Toyka
Escalating immunotherapy of multiple sclerosis.Austrian-German- Swiss Multiple Sclerosis Therapy Consensus Group [MSTCG].
European neurology 1999;42(3):121-7.
1999: Christiane Schneider; Marinos C Dalakas; Klaus V Toyka; G Said; Hans-Peter Hartung; Ralf Gold
T-cell apoptosis in inflammatory neuromuscular disorders associated with human immunodeficiency virus infection.
Archives of neurology 1999;56(1):79-83.
1999: Kenneth Ricker; Tiemo Grimm; Manuela C Koch; Christiane Schneider; Wolfram Kress; C D Reimers; Wilhelm Schulte-Mattler; B Mueller-Myhsok; Klaus V Toyka; CR Mueller
Linkage of proximal myotonic myopathy to chromosome 3q.
Neurology 1999;52(1):170-1.
1998: Markus Naumann; E Hofmann; Klaus V Toyka
Multifocal brain MRI hypointensities secondary to embolic metal fragments from a mechanical heart valve prosthesis: a possible source of epileptic seizures.
Neurology 1998;51(6):1766-7.
1998: Markus Naumann; Klaus V Toyka; B Mansouri Taleghani; J Ahmadpour; Karlheinz Reiners; H Bigalke
Depletion of neutralising antibodies resensitises a secondary non-responder to botulinum A neurotoxin.
Journal of neurology, neurosurgery, and psychiatry 1998;65(6):924-7.
1998: Brigitte Buchwald; Klaus V Toyka; Jürgen Zielasek; Andreas Weishaupt; S Schweiger; Josef Dudel
Neuromuscular blockade by IgG antibodies from patients with Guillain-Barré syndrome: a macro-patch-clamp study.
Annals of neurology 1998;44(6):913-22.
1998: R D M Hadden; David R Cornblath; Richard AC Hughes; Jürgen Zielasek; H P Hartung; Klaus V Toyka; Anthony V Swan
Electrophysiological classification of Guillain-Barré syndrome: clinical associations and outcome. Plasma Exchange/Sandoglobulin Guillain-Barré Syndrome Trial Group.
Annals of neurology 1998;44(5):780-8.
1998: I Bergmann; R Reiter; Klaus V Toyka; Martin Koltzenburg
Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75.
Neuroscience letters 1998;255(2):87-90.
1998: Rudolf Martini; Jürgen Zielasek; Klaus V Toyka
Inherited demyelinating neuropathies: from gene to disease.
Current opinion in neurology 1998;11(5):545-56.
1998: G Ochs; M Loew; Jörg-Christian Tonn; Klaus V Toyka
Distribution, tolerability and tissue compatibility of intrathecal tizanidine in the sheep.
Acta anaesthesiologica Scandinavica 1998;42(7):786-93.
1998: U Enders; Roy R Lobb; R Blake Pepinsky; Hans-Peter Hartung; Klaus V Toyka; Ralf Gold
The role of the very late antigen-4 and its counterligand vascular cell adhesion molecule-1 in the pathogenesis of experimental autoimmune neuritis of the Lewis rat.
Brain : a journal of neurology 1998;121 ( Pt 7)():1257-66.
1998: A Chan; Ralf Gold; S Arp; K W Pflughaupt; Klaus V Toyka; Heinz Reichmann
[Standardized bicycle ergometry test in mitochondrial myopathies. Indications, interferences and clinical parameters].
Der Nervenarzt 1998;69(6):472-84.
1998: Brigitte Buchwald; Josef Dudel; Klaus V Toyka
Neuromuscular blockade by immunoglobulin G from patients with Miller Fisher syndrome.
Annals of the New York Academy of Sciences 1998;841():659-69.
1998: Reinhard Kiefer; Tilmann Schweitzer; Stefan Jung; Klaus V Toyka; Hans-Peter Hartung
Sequential expression of transforming growth factor-beta1 by T-cells, macrophages, and microglia in rat spinal cord during autoimmune inflammation.
Journal of neuropathology and experimental neurology 1998;57(5):385-95.
1998: Peter Flachenecker; Behrouz Mansouri Taleghani; Ralf Gold; Ralf Grossmann; D Wiebecke; Klaus V Toyka
Treatment of severe myasthenia gravis with protein A immunoadsorption and cyclophosphamide.
Transfusion science 1998;19 Suppl():43-6.
1998: Reinhard Kiefer; Bernd C Kieseier; Wolfgang Brück; Hans-Peter Hartung; Klaus V Toyka
Macrophage differentiation antigens in acute and chronic autoimmune polyneuropathies.
Brain : a journal of neurology 1998;121 ( Pt 3)():469-79.
1998: Markus Naumann; U Hofmann; I Bergmann; Henning Hamm; Klaus V Toyka; Karlheinz Reiners
Focal hyperhidrosis: effective treatment with intracutaneous botulinum toxin.
Archives of dermatology 1998;134(3):301-4.
1998: J Knieling; H Weiss; Hermann Faller; H Lang; Berthold Schalke; Klaus V Toyka
[Follow-up of myasthenia gravis. Results of a longitudinal study of the significance of psychosocial predictors].
Der Nervenarzt 1998;69(2):137-44.
1998: Ralf Giess; R Goetz; B Schrank; G Ochs; Michael Sendtner; Klaus V Toyka
Potential implications of a ciliary neurotrophic factor gene mutation in a German population of patients with motor neuron disease.
Muscle & nerve 1998;21(2):236-8.
1998: Brigitte Buchwald; Andreas Weishaupt; Klaus V Toyka; Josef Dudel
Pre- and postsynaptic blockade of neuromuscular transmission by Miller-Fisher syndrome IgG at mouse motor nerve terminals.
The European journal of neuroscience 1998;10(1):281-90.
1998: Juan J Archelos; J Trotter; Stefano C Previtali; Benedikt Weissbrich; Klaus V Toyka; Hans-Peter Hartung
Isolation and characterization of an oligodendrocyte precursor-derived B-cell epitope in multiple sclerosis.
Annals of neurology 1998;43(1):15-24.
1997: Niels Kruse; M Pette; Klaus V Toyka; Peter Rieckmann
Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood.
Journal of immunological methods 1997;210(2):195-203.
1997: Stefan Jung; T Donhauser; Klaus V Toyka; Hans-Peter Hartung
Propentofylline and iloprost suppress the production of TNF-alpha by macrophages but fail to ameliorate experimental autoimmune encephalomyelitis in Lewis rats.
Journal of autoimmunity 1997;10(6):519-29.
1997: Klaus V Toyka; Jürgen Zielasek; K Ricker; K Adlkofer; Ueli Suter
Hereditary neuromyotonia: a mouse model associated with deficiency or increased gene dosage of the PMP22 gene.
Journal of neurology, neurosurgery, and psychiatry 1997;63(6):812-3.
1997: Markus Naumann; M Zellner; Klaus V Toyka; Karlheinz Reiners
Treatment of gustatory sweating with botulinum toxin.
Annals of neurology 1997;42(6):973-5.
1997: Claudia Sommer; C Schmidt; Annette George; Klaus V Toyka
A metalloprotease-inhibitor reduces pain associated behavior in mice with experimental neuropathy.
Neuroscience letters 1997;237(1):45-8.
1997: Stefanie Gaupp; Hans-Peter Hartung; Klaus V Toyka; Stefan Jung
Modulation of experimental autoimmune neuritis in Lewis rats by oral application of myelin antigens.
Journal of neuroimmunology 1997;79(2):129-37.
1997: Franz X Weilbach; Stefan Jung; Hans-Peter Hartung; Klaus V Toyka; G Giegerich
T-cell receptor V beta-element expression in peripheral nerves of Lewis rats suffering from experimental autoimmune neuritis.
Journal of neuroimmunology 1997;79(1):69-75.
1997: B Schrank; Rudolf Götz; Jennifer Gunnersen; J M Ure; Klaus V Toyka; A G Smith; Michael Sendtner
Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9920-5.
1997: A Lindner; Berthold Schalke; Klaus V Toyka
Outcome in juvenile-onset myasthenia gravis: a retrospective study with long-term follow-up of 79 patients.
Journal of neurology 1997;244(8):515-20.
1997: K Adlkofer; R Frei; DH Neuberg; Jürgen Zielasek; Klaus V Toyka; Ueli Suter
Heterozygous peripheral myelin protein 22-deficient mice are affected by a progressive demyelinating tomaculous neuropathy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(12):4662-71.
1997: P Anzini; DH Neuberg; Melitta Schachner; E Nelles; K Willecke; Jürgen Zielasek; Klaus V Toyka; Ueli Suter; Rudolf Martini
Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(12):4545-51.
1997: U Enders; Klaus V Toyka; Hans-Peter Hartung; Ralf Gold
Failure of intravenous immunoglobulin (IVIg) therapy in experimental autoimmune neuritis (EAN) of the Lewis rat.
Journal of neuroimmunology 1997;76(1-2):112-6.
1997: Heinz Reichmann; H H Goebel; Christiane Schneider; Klaus V Toyka
Familial mixed congenital myopathy with rigid spine phenotype.
Muscle & nerve 1997;20(4):411-7.
1997: Andreas Weishaupt; Ralf Gold; Stefanie Gaupp; G Giegerich; Hans-Peter Hartung; Klaus V Toyka
Antigen therapy eliminates T cell inflammation by apoptosis: effective treatment of experimental autoimmune neuritis with recombinant myelin protein P2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1338-43.
1997: I Bergmann; J V Priestley; Stephen McMahon; Eva-B Bröcker; Klaus V Toyka; Martin Koltzenburg
Analysis of cutaneous sensory neurons in transgenic mice lacking the low affinity neurotrophin receptor p75.
The European journal of neuroscience 1997;9(1):18-28.
1997: Georg Becker; Markus Naumann; M Scheubeck; E Hofmann; M Deimling; A Lindner; G Gahn; Christoph Reiners; Klaus V Toyka; Karlheinz Reiners
Comparison of transcranial sonography, magnetic resonance imaging, and single photon emission computed tomography findings in idiopathic spasmodic torticollis.
Movement disorders : official journal of the Movement Disorder Society 1997;12(1):79-88.
1996: C Schneider; Ralf Gold; M C Dalakas; M Schmied; H Lassmann; Klaus V Toyka; Hans-Peter Hartung
MHC class I-mediated cytotoxicity does not induce apoptosis in muscle fibers nor in inflammatory T cells: studies in patients with polymyositis, dermatomyositis, and inclusion body myositis.
Journal of neuropathology and experimental neurology 1996;55(12):1205-9.
1996: Markus Naumann; Georg Becker; Klaus V Toyka; Tillmann Supprian; Karlheinz Reiners
Lenticular nucleus lesion in idiopathic dystonia detected by transcranial sonography.
Neurology 1996;47(5):1284-90.
1996: F Dittrich; G Ochs; A Grosse-Wilde; U Berweiler; Q Yan; J A Miller; Klaus V Toyka; Michael Sendtner
Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons.
Experimental neurology 1996;141(2):225-39.
1996: E Nelles; C Bützler; D Jung; Achim Temme; H D Gabriel; U Dahl; Otto Traub; F Stümpel; K Jungermann; Jürgen Zielasek; Klaus V Toyka; Rolf Dermietzel; Klaus Willecke
Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9565-70.
1996: Klaus V Toyka
The immune system in neurologic disease: selected recent developments.
Acta neurologica Belgica 1996;96(3):185-8.
1996: Ralf Gold; R B Pepinsky; Uwe K Zettl; Klaus V Toyka; Hans-Peter Hartung
Lipocortin-1 (annexin-1) suppresses activation of autoimmune T cell lines in the Lewis rat.
Journal of neuroimmunology 1996;69(1-2):157-64.
1996: O Bourde; Reinhard Kiefer; Klaus V Toyka; Hans-Peter Hartung
Quantification of interleukin-6 mRNA in wallerian degeneration by competitive reverse transcription polymerase chain reaction.
Journal of neuroimmunology 1996;69(1-2):135-40.
1996: S P Morrissey; Ralf Deichmann; J Syha; C Simonis; Uwe K Zettl; Juan J Archelos; Stefan Jung; H Stodal; H Lassmann; Klaus V Toyka; Axel Haase; Hans-Peter Hartung
Partial inhibition of AT-EAE by an antibody to ICAM-1: clinico-histological and MRI studies.
Journal of neuroimmunology 1996;69(1-2):85-93.
1996: Ralf Gold; Jürgen Zielasek; J M Schröder; B Sellhaus; Jesse Cedarbaum; Hans-Peter Hartung; Michael Sendtner; Klaus V Toyka
Treatment with ciliary neurotrophic factor does not improve regeneration in experimental autoimmune neuritis of the Lewis rat.
Muscle & nerve 1996;19(9):1177-80.
1996: Josef Magyar; Rudolf Martini; T Ruelicke; Adriano Aguzzi; K Adlkofer; Z Dembic; Jürgen Zielasek; Klaus V Toyka; Ueli Suter
Impaired differentiation of Schwann cells in transgenic mice with increased PMP22 gene dosage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(17):5351-60.
1996: Stefan Jung; Klaus V Toyka; Hans-Peter Hartung
T cell directed immunotherapy of inflammatory demyelination in the peripheral nervous system. Potent suppression of the effector phase of experimental autoimmune neuritis by anti-CD2 antibodies.
Brain : a journal of neurology 1996;119 ( Pt 4)():1079-90.
1996: Stefan Jung; Jürgen Zielasek; G Köllner; T Donhauser; Klaus V Toyka; Hans-Peter Hartung
Preventive but not therapeutic application of Rolipram ameliorates experimental autoimmune encephalomyelitis in Lewis rats.
Journal of neuroimmunology 1996;68(1-2):1-11.
1996: Jürgen Zielasek; Rudolf Martini; Klaus V Toyka
Functional abnormalities in P0-deficient mice resemble human hereditary neuropathies linked to P0 gene mutations.
Muscle & nerve 1996;19(8):946-52.
1996: Klaus V Toyka; Hans-Peter Hartung
Chronic inflammatory polyneuritis and neuropathies.
Current opinion in neurology 1996;9(3):240-50.
1996: Alexander Marx; A Wilisch; A Schultz; Axel Greiner; Barbara Magi; Vitaliano Pallini; Berthold Schalke; Klaus V Toyka; Wilfred Nix; Thomas Kirchner; Hans Konrad Müller-Hermelink
Expression of neurofilaments and of a titin epitope in thymic epithelial tumors. Implications for the pathogenesis of myasthenia gravis.
The American journal of pathology 1996;148(6):1839-50.
1996: Hans-Peter Hartung; Jürgen Zielasek; Stefan Jung; Klaus V Toyka
Effector mechanisms in demyelinating neuropathies.
Revue neurologique 1996;152(5):320-7.
1996: Martin Winterholler; D Claus; A Bockelbrink; Gian Domenico Borasio; Dieter Pongratz; B Schrank; Klaus V Toyka; Bernhard Neundörfer
[Home ventilation in neuromuscular diseases in adults. Presentation of recommendations of the Bavarian Muscle Centers of the DGM].
Medizinische Klinik (Munich, Germany : 1983) 1996;91 Suppl 2():45-7.
1996: Ralf Gold; M Schmied; U Tontsch; Hans-Peter Hartung; H Wekerle; Klaus V Toyka; H Lassmann
Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death. A model for T-cell apoptosis in vivo.
Brain : a journal of neurology 1996;119 ( Pt 2)():651-9.
1996: B Schmidt; Klaus V Toyka; Reinhard Kiefer; J Full; Hans-Peter Hartung; J Pollard
Inflammatory infiltrates in sural nerve biopsies in Guillain-Barre syndrome and chronic inflammatory demyelinating neuropathy.
Muscle & nerve 1996;19(4):474-87.
1996: Ralf Gold; Jürgen Zielasek; Reinhard Kiefer; Klaus V Toyka; Hans-Peter Hartung
Secretion of nitrite by Schwann cells and its effect on T-cell activation in vitro.
Cellular immunology 1996;168(1):69-77.
1996: Markus Naumann; Heinz Reichmann; H H Goebel; C Moll; Klaus V Toyka
Glucocorticoid-sensitive hereditary inclusion body myositis.
Journal of neurology 1996;243(2):126-30.
1996: S P Morrissey; H Stodal; Uwe K Zettl; C Simonis; Stefan Jung; Reinhard Kiefer; H Lassmann; Hans-Peter Hartung; Axel Haase; Klaus V Toyka
In vivo MRI and its histological correlates in acute adoptive transfer experimental allergic encephalomyelitis. Quantification of inflammation and oedema.
Brain : a journal of neurology 1996;119 ( Pt 1)():239-48.
1996: Hans-Peter Hartung; H Willison; Stefan Jung; M Pette; Klaus V Toyka; G Giegerich
Autoimmune responses in peripheral nerve.
Springer seminars in immunopathology 1996;18(1):97-123.
1996: U K Zetti; Ralf Gold; Klaus V Toyka; Hans-Peter Hartung
In situ demonstration of T cell activation and elimination in the peripheral nervous system during experimental autoimmune neuritis in the Lewis rat.
Acta neuropathologica 1996;91(4):360-7.
1996: M Stangel; Uwe K Zettl; Eilhard Mix; J Zielasek; Klaus V Toyka; Hans-Peter Hartung; Ralf Gold
H2O2 and nitric oxide-mediated oxidative stress induce apoptosis in rat skeletal muscle myoblasts.
Journal of neuropathology and experimental neurology 1996;55(1):36-43.
1996: Reinhard Kiefer; K Funa; Tilmann Schweitzer; Stefan Jung; O Bourde; Klaus V Toyka; Hans-Peter Hartung
Transforming growth factor-beta 1 in experimental autoimmune neuritis. Cellular localization and time course.
The American journal of pathology 1996;148(1):211-23.
1995: Andreas Weishaupt; G Giegerich; Stefan Jung; Ralf Gold; U Enders; M Pette; K Hayasaka; Hans-Peter Hartung; Klaus V Toyka
T cell antigenic and neuritogenic activity of recombinant human peripheral myelin P2 protein.
Journal of neuroimmunology 1995;63(2):149-56.
1995: Brigitte Buchwald; Andreas Weishaupt; Klaus V Toyka; Josef Dudel
Immunoglobulin G from a patient with Miller-Fisher syndrome rapidly and reversibly depresses evoked quantal release at the neuromuscular junction of mice.
Neuroscience letters 1995;201(2):163-6.
1995: Stefan Jung; Klaus V Toyka; Hans-Peter Hartung
Soluble complement receptor type 1 inhibits experimental autoimmune neuritis in Lewis rats.
Neuroscience letters 1995;200(3):167-70.
1995: Peter Flachenecker; Klaus V Toyka; Hans-Peter Hartung
[Active vaccinations in multiple sclerosis].
Deutsche medizinische Wochenschrift (1946) 1995;120(44):1513-6.
1995: Rudolf Martini; Jürgen Zielasek; Klaus V Toyka; peter giese; Melitta Schachner
Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies.
Nature genetics 1995;11(3):281-6.
1995: K Adlkofer; Rudolf Martini; Adriano Aguzzi; Jürgen Zielasek; Klaus V Toyka; Ueli Suter
Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice.
Nature genetics 1995;11(3):274-80.
1995: Ralf Gold; Klaus V Toyka; Hans-Peter Hartung
Synergistic effect of IFN-gamma and TNF-alpha on expression of immune molecules and antigen presentation by Schwann cells.
Cellular immunology 1995;165(1):65-70.
1995: Franz X Weilbach; Klaus V Toyka; Hans-Peter Hartung
[Oral, low-dosage methotrexate in chronic progressive multiple sclerosis. A preliminary critical analysis].
Der Nervenarzt 1995;66(8):643-7.
1995: Hans-Peter Hartung; Karlheinz Reiners; Juan J Archelos; M Michels; P Seeldrayers; F Heidenreich; K W Pflughaupt; Klaus V Toyka
Circulating adhesion molecules and tumor necrosis factor receptor in multiple sclerosis: correlation with magnetic resonance imaging.
Annals of neurology 1995;38(2):186-93.
1995: Markus Naumann; Berthold Schalke; Thomas Klopstock; Heinz Reichmann; K W Lange; Gerhard A Wiesbeck; Klaus V Toyka; Karlheinz Reiners
Neurological multisystem manifestation in multiple symmetric lipomatosis: a clinical and electrophysiological study.
Muscle & nerve 1995;18(7):693-8.
1995: Uwe K Zettl; Ralf Gold; Klaus V Toyka; Hans-Peter Hartung
Intravenous glucocorticosteroid treatment augments apoptosis of inflammatory T cells in experimental autoimmune neuritis (EAN) of the Lewis rat.
Journal of neuropathology and experimental neurology 1995;54(4):540-7.
1995: Heinz Reichmann; Berthold Schalke; P Seibel; Markus Naumann; Klaus V Toyka
Sarcoid myopathy and mitochondrial respiratory chain defects: clinicopathological, biochemical and molecular biological analyses.
Neuromuscular disorders : NMD 1995;5(4):277-83.
1995: Ralf Gold; G Giegerich; Hans-Peter Hartung; Klaus V Toyka
T-cell receptor (TCR) usage in Lewis rat experimental autoimmune encephalomyelitis: TCR beta-chain-variable-region V beta 8.2-positive T cells are not essential for induction and course of disease.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):5850-4.
1995: Hans-Peter Hartung; Juan J Archelos; Jürgen Zielasek; Ralf Gold; Martin Koltzenburg; Karlheinz Reiners; Klaus V Toyka
Circulating adhesion molecules and inflammatory mediators in demyelination: a review.
Neurology 1995;45(6 Suppl 6):S22-32.
1995: M Pette; Ralf Gold; D F Pette; Hans-Peter Hartung; Klaus V Toyka
Mafosfamide induces DNA fragmentation and apoptosis in human T-lymphocytes. A possible mechanism of its immunosuppressive action.
Immunopharmacology 1995;30(1):59-69.
1995: Stefan Jung; Klaus V Toyka; Hans-Peter Hartung
Suppression of experimental autoimmune encephalomyelitis in Lewis rats by antibodies against CD2.
European journal of immunology 1995;25(5):1391-8.
1995: G K Harvey; Klaus V Toyka; Jürgen Zielasek; Reinhard Kiefer; C Simonis; Hans-Peter Hartung
Failure of anti-GM1 IgG or IgM to induce conduction block following intraneural transfer.
Muscle & nerve 1995;18(4):388-94.
1995: Jürgen Zielasek; Stefan Jung; Ralf Gold; F Y Liew; Klaus V Toyka; Hans-Peter Hartung
Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 1995;58(1):81-8.
1995: Hans-Peter Hartung; J D Pollard; G K Harvey; Klaus V Toyka
Immunopathogenesis and treatment of the Guillain-Barré syndrome--Part II.
Muscle & nerve 1995;18(2):154-64.
1995: Hans-Peter Hartung; J D Pollard; G K Harvey; Klaus V Toyka
Immunopathogenesis and treatment of the Guillain-Barré syndrome--Part I.
Muscle & nerve 1995;18(2):137-53.
1995: Jürgen Zielasek; Heinz Reichmann; H Künzig; Stefan Jung; Hans-Peter Hartung; Klaus V Toyka
Inhibition of brain macrophage/microglial respiratory chain enzyme activity in experimental autoimmune encephalomyelitis of the Lewis rat.
Neuroscience letters 1995;184(2):129-32.
1995: Michael Sendtner; R A Hughes; F Dittrich; Bettina Holtmann; Y Masu; P Carroll; G Ochs; Klaus V Toyka; H Thoenen
Ciliary neurotrophic factor (CNTF): physiological and pharmacological effects.
Restorative neurology and neuroscience 1995;8(1):95-6.
1995: Ralf Gold; Hans-Peter Hartung; Klaus V Toyka
[Therapy with immunoglobulins in neurologic autoimmune diseases. Indications and mechanism of action].
Fortschritte der Neurologie-Psychiatrie 1995;63(1):17-29.
1995: G Giegerich; M Stangel; N Torres-Nagel; Thomas Hünig; Klaus V Toyka
Sequence and diversity of rat T-cell receptor Tcra V8 gene segments.
Immunogenetics 1995;42(4):304-5.
1994: M Pette; Hans-Peter Hartung; Klaus V Toyka
[Immune augmenting therapy as treatment of multiple sclerosis. Warning regarding a potentially toxic alternative treatment method].
Der Nervenarzt 1994;65(12):878-90.
1994: Hans-Peter Hartung; Ralf Gold; Jürgen Zielasek; Juan J Archelos; Klaus V Toyka
[Therapy of acute polyradiculoneuritis (Guillain-Barré syndrome)].
Der Nervenarzt 1994;65(12):807-18.
1994: Stefan Jung; Hermann J Schluesener; B Schmidt; A Fontana; Klaus V Toyka; Hans-Peter Hartung
Therapeutic effect of transforming growth factor-beta 2 on actively induced EAN but not adoptive transfer EAN.
Immunology 1994;83(4):545-51.
1994: Stefan Jung; Klaus V Toyka; Hans-Peter Hartung
Impact of 15-deoxyspergualin on effector cells in experimental autoimmune diseases of the nervous system in the Lewis rat.
Clinical and experimental immunology 1994;98(3):494-502.
1994: M Pette; C Linington; C Gengaroli; H Grosse-Wilde; Klaus V Toyka; Hans-Peter Hartung
T lymphocyte recognition sites on peripheral nerve myelin P0 protein.
Journal of neuroimmunology 1994;54(1-2):29-34.
1994: M Stangel; Klaus V Toyka; Hans-Peter Hartung; G Giegerich
Bacterial expression of a soluble T-cell receptor alpha chain.
Biochemical and biophysical research communications 1994;202(3):1280-4.
1994: Ralf Gold; M Schmied; G Giegerich; H Breitschopf; Hans-Peter Hartung; Klaus V Toyka; H Lassmann
Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques.
Laboratory investigation; a journal of technical methods and pathology 1994;71(2):219-25.
1994: G K Harvey; Klaus V Toyka; Hans-Peter Hartung
Effects of mast cell degranulation on blood-nerve barrier permeability and nerve conduction in vivo.
Journal of the neurological sciences 1994;125(1):102-9.
1994: Uwe K Zettl; Ralf Gold; Hans-Peter Hartung; Klaus V Toyka
Apoptotic cell death of T-lymphocytes in experimental autoimmune neuritis of the Lewis rat.
Neuroscience letters 1994;176(1):75-9.
1994: Jürgen Zielasek; G Ritter; S Magi; Hans-Peter Hartung; Klaus V Toyka
A comparative trial of anti-glycoconjugate antibody assays: IgM antibodies to GM1.
Journal of neurology 1994;241(8):475-80.
1994: Hans-Peter Hartung; Karlheinz Reiners; M Michels; R A Hughes; F Heidenreich; Jürgen Zielasek; U Enders; Klaus V Toyka
Serum levels of soluble E-selectin (ELAM-1) in immune-mediated neuropathies.
Neurology 1994;44(6):1153-8.
1994: M Pette; C Gengaroli; Hans-Peter Hartung; A Greiner; G Giegerich; Klaus V Toyka
Human T lymphocytes distinguish bovine from human P2 peripheral myelin protein: implications for immunological studies on inflammatory demyelinating neuropathies.
Journal of neuroimmunology 1994;52(1):47-52.
1994: Juan J Archelos; Mathias Mäurer; Stefan Jung; M Miyasaka; T Tamatani; Klaus V Toyka; Hans-Peter Hartung
Inhibition of experimental autoimmune neuritis by an antibody to the lymphocyte function-associated antigen-1.
Laboratory investigation; a journal of technical methods and pathology 1994;70(5):667-75.
1994: Thomas Klopstock; Markus Naumann; Berthold Schalke; F Bischof; P Seibel; M Kottlors; P Eckert; Karlheinz Reiners; Klaus V Toyka; Heinz Reichmann
Multiple symmetric lipomatosis: abnormalities in complex IV and multiple deletions in mitochondrial DNA.
Neurology 1994;44(5):862-6.
1994: M Pette; Hans-Peter Hartung; Klaus V Toyka
[Cyclophosphamide in therapy of chronic progressive multiple sclerosis. Critical analysis of current studies].
Der Nervenarzt 1994;65(4):271-4.
1994: Reinhard Kiefer; M L Supler; Klaus V Toyka; Wolfgang J Streit
In situ detection of transforming growth factor-beta mRNA in experimental rat glioma and reactive glial cells.
Neuroscience letters 1994;166(2):161-4.
1993: Markus Naumann; Klaus V Toyka; H H Goebel; E Hofmann; Heinz Reichmann
Focal myositis of the temporal muscle.
Muscle & nerve 1993;16(12):1374-6.
1993: Stefan Jung; I Huitinga; B Schmidt; Jürgen Zielasek; C D Dijkstra; Klaus V Toyka; Hans-Peter Hartung
Selective elimination of macrophages by dichlormethylene diphosphonate-containing liposomes suppresses experimental autoimmune neuritis.
Journal of the neurological sciences 1993;119(2):195-202.
1993: Hans-Peter Hartung; M Michels; Karlheinz Reiners; P Seeldrayers; Juan J Archelos; Klaus V Toyka
Soluble ICAM-1 serum levels in multiple sclerosis and viral encephalitis.
Neurology 1993;43(11):2331-5.
1993: M Pette; U. Liebert; U Göbel; H Grosse-Wilde; Hans-Peter Hartung; Klaus V Toyka
Measles virus-directed responses of CD4+ T lymphocytes in MS patients and healthy individuals.
Neurology 1993;43(10):2019-25.
1993: Juan J Archelos; Mathias Mäurer; Stefan Jung; Klaus V Toyka; Hans-Peter Hartung
Suppression of experimental allergic neuritis by an antibody to the intracellular adhesion molecule ICAM-1.
Brain : a journal of neurology 1993;116 ( Pt 5)():1043-58.
1993: U Enders; Helge Karch; Klaus V Toyka; M Michels; Jürgen Zielasek; M Pette; J Heesemann; Hans-Peter Hartung
The spectrum of immune responses to Campylobacter jejuni and glycoconjugates in Guillain-Barré syndrome and in other neuroimmunological disorders.
Annals of neurology 1993;34(2):136-44.
1993: Juan J Archelos; Stefan Jung; Mathias Mäurer; M Schmied; H Lassmann; T Tamatani; M Miyasaka; Klaus V Toyka; Hans-Peter Hartung
Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM-1.
Annals of neurology 1993;34(2):145-54.
1993: Juan J Archelos; K Roggenbuck; Jürgen Schneider-Schaulies; Klaus V Toyka; Hans-Peter Hartung
Detection and quantification of antibodies to the extracellular domain of P0 during experimental allergic neuritis.
Journal of the neurological sciences 1993;117(1-2):197-205.
1993: Stefan Jung; Hermann J Schluesener; Klaus V Toyka; Hans-Peter Hartung
Modulation of EAE by vaccination with T cell receptor peptides: V beta 8 T cell receptor peptide-specific CD4+ lymphocytes lack direct immunoregulatory activity.
Journal of neuroimmunology 1993;45(1-2):15-22.
1993: Juan J Archelos; K Roggenbuck; Jürgen Schneider-Schaulies; C Linington; Klaus V Toyka; Hans-Peter Hartung
Production and characterization of monoclonal antibodies to the extracellular domain of P0.
Journal of neuroscience research 1993;35(1):46-53.
1993: Jürgen Zielasek; Juan J Archelos; Klaus V Toyka; Hans-Peter Hartung
Expression of intercellular adhesion molecule-1 on rat microglial cells.
Neuroscience letters 1993;153(2):136-9.
1993: Jürgen Zielasek; Stefan Jung; B Schmidt; G Ritter; Hans-Peter Hartung; Klaus V Toyka
Effects of ganglioside administration on experimental autoimmune neuritis induced by peripheral nerve myelin or P2-specific T cell lines.
Journal of neuroimmunology 1993;43(1-2):103-11.
1992: Hans-Peter Hartung; Stefan Jung; G Stoll; Jürgen Zielasek; B Schmidt; Juan J Archelos; Klaus V Toyka
Inflammatory mediators in demyelinating disorders of the CNS and PNS.
Journal of neuroimmunology 1992;40(2-3):197-210.
1992: A Pohl-Koppe; C Dahm; Joachim E Kühn; J Hamann; U Fuhrmeister; M Gabriel; W Grüninger; H Metze; M Ranke; Klaus V Toyka
[New aspects in the diagnosis of herpes simplex virus encephalitis--case reports and virologic findings].
Der Nervenarzt 1992;63(8):495-50.
1992: Stefan Jung; S Krämer; Hermann J Schluesener; Thomas Hünig; Klaus V Toyka; Hans-Peter Hartung
Prevention and therapy of experimental autoimmune neuritis by an antibody against T cell receptors-alpha/beta.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(12):3768-75.
1992: Jürgen Zielasek; M Tausch; Klaus V Toyka; Hans-Peter Hartung
Production of nitrite by neonatal rat microglial cells/brain macrophages.
Cellular immunology 1992;141(1):111-20.
1992: K I Geuder; Alexander Marx; V Witzemann; Berthold Schalke; Klaus V Toyka; Thomas Kirchner; Hans Konrad Müller-Hermelink
Pathogenetic significance of fetal-type acetylcholine receptors on thymic myoid cells in myasthenia gravis.
Developmental immunology 1992;2(2):69-75.
1991: Stefan Jung; Hermann J Schluesener; Klaus V Toyka; Hans-Peter Hartung
T cell vaccination does not induce resistance to experimental autoimmune neuritis.
Journal of neuroimmunology 1991;35(1-3):1-11.
1991: Hans-Peter Hartung; Karlheinz Reiners; B Schmidt; G Stoll; Klaus V Toyka
Serum interleukin-2 concentrations in Guillain-Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy: comparison with other neurological diseases of presumed immunopathogenesis.
Annals of neurology 1991;30(1):48-53.
1990: Hans-Peter Hartung; Klaus V Toyka
T-cell and macrophage activation in experimental autoimmune neuritis and Guillain-Barré syndrome.
Annals of neurology 1990;27 Suppl():S57-63.