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Tatsushi Toyokuni

Research Profile

Procedures

Living Beings

Chemicals & Drugs

Genes & Molecular Sequences

Genes, Reporter

Physiology

Gene Expression

Anatomy

Tumor Cells, Cultured

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Publications

TOP 3
Tatsushi Toyokuni; J S Dileep Kumar; Joseph Walsh; Alan Shapiro; John J Talley; Michael E Phelps; Harvey R Herschman; Jorge R Barrio; Nagichettiar Satyamurthy
Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography.
Andrew J Norris; Julian P Whitelegge; Arman Yaghoubian; Jean-René Alattia; Gilbert G Privé; Tatsushi Toyokuni; Hubert Sun; Mai N Brooks; Luigi Panza; Pamela Matto; Federica Compostella; Natascha Remmel; Ralf Klingenstein; Konrad Sandhoff; Claire Fluharty; Arvan L Fluharty; Kym F Faull
A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A.
Tatsushi Toyokuni; J S Dileep Kumar; Paula Gunawan; Ernest S Basarah; Jie Liu; Jorge R Barrio; Nagichettiar Satyamurthy
Practical and reliable synthesis of 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-beta-D-mannopyranose, a precursor of 2-deoxy-2-[18F]fluoro-D-glucose (FDG).

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All Publications

2005: Tatsushi Toyokuni; J S Dileep Kumar; Joseph Walsh; Alan Shapiro; John J Talley; Michael E Phelps; Harvey R Herschman; Jorge R Barrio; Nagichettiar Satyamurthy
Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography.
Bioorganic & medicinal chemistry letters 2005;15(21):4699-702.
2005: Andrew J Norris; Julian P Whitelegge; Arman Yaghoubian; Jean-René Alattia; Gilbert G Privé; Tatsushi Toyokuni; Hubert Sun; Mai N Brooks; Luigi Panza; Pamela Matto; Federica Compostella; Natascha Remmel; Ralf Klingenstein; Konrad Sandhoff; Claire Fluharty; Arvan L Fluharty; Kym F Faull
A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A.
Journal of lipid research 2005;46(10):2254-64.
2004: Tatsushi Toyokuni; J S Dileep Kumar; Paula Gunawan; Ernest S Basarah; Jie Liu; Jorge R Barrio; Nagichettiar Satyamurthy
Practical and reliable synthesis of 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-beta-D-mannopyranose, a precursor of 2-deoxy-2-[18F]fluoro-D-glucose (FDG).
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(5):324-30.
2004: Andrew J Norris; Julian P Whitelegge; M Jane Strouse; Kym F Faull; Tatsushi Toyokuni
Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism.
Bioorganic & medicinal chemistry letters 2004;14(3):571-3.
2003: Tatsushi Toyokuni; Joseph Walsh; Alan Dominguez; Michael E Phelps; Jorge R Barrio; Sanjiv S Gambhir; Nagichettiar Satyamurthy
Synthesis of a new heterobifunctional linker, N-[4-(aminooxy)butyl]maleimide, for facile access to a thiol-reactive 18F-labeling agent.
Bioconjugate chemistry 2003;14(6):1253-9.
2002: Miklós Sahin-Tóth; Paula Gunawan; Mary C Lawrence; Tatsushi Toyokuni; H Ronald Kaback
Binding of hydrophobic D-galactopyranosides to the lactose permease of Escherichia coli.
Biochemistry 2002;41(43):13039-45.
2002: Nona Adonai; Nora Adonai; Khoi N Nguyen; Joseph Walsh; Meera Iyer; Tatsushi Toyokuni; Michael E Phelps; Timothy McCarthy; Deborah W McCarthy; Sanjiv S Gambhir
Ex vivo cell labeling with 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3030-5.
2001: Andrew J Norris; Julian P Whitelegge; Kym F Faull; Tatsushi Toyokuni
Kinetic characterization of enzyme inhibitors using electrospray-ionization mass spectrometry coupled with multiple reaction monitoring.
Analytical chemistry 2001;73(24):6024-9.
2001: X Sun; Alexander Annala; Shahriar S Yaghoubi; Jorge R Barrio; K N Nguyen; Tatsushi Toyokuni; Nagichettiar Satyamurthy; Mohammad Namavari; Michael E Phelps; Harvey R Herschman; Sanjiv S Gambhir
Quantitative imaging of gene induction in living animals.
Gene therapy 2001;8(20):1572-9.
2001: Qianwa Liang; Nagichettiar Satyamurthy; Jorge R Barrio; Tatsushi Toyokuni; M P Phelps; Sanjiv S Gambhir; Harvey R Herschman
Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction.
Gene therapy 2001;8(19):1490-8.
2001: Shahriar S Yaghoubi; Lily Wu; Qianwa Liang; Tatsushi Toyokuni; Jorge R Barrio; Mohammad Namavari; Nagichettiar Satyamurthy; Michael E Phelps; Harvey R Herschman; Sanjiv S Gambhir
Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors.
Gene therapy 2001;8(14):1072-80.
2001: J S Dileep Kumar; F Y Dupradeau; M Jane Strouse; Michael E Phelps; Tatsushi Toyokuni
Electrophilic azidation for stereoselective synthesis of 2-azido-2-deoxyaldono-1,5-lactones.
The Journal of organic chemistry 2001;66(9):3220-3.
2001: Andrew J Norris; Julian P Whitelegge; Kym F Faull; Tatsushi Toyokuni
Analysis of enzyme kinetics using electrospray ionization mass spectrometry and multiple reaction monitoring: fucosyltransferase V.
Biochemistry 2001;40(13):3774-9.
2001: Meera Iyer; Jorge R Barrio; Mohammad Namavari; Eileen Bauer; Nagichettiar Satyamurthy; Khoi Nguyen; Tatsushi Toyokuni; Michael E Phelps; Harvey R Herschman; Sanjiv S Gambhir
8-[18F]Fluoropenciclovir: an improved reporter probe for imaging HSV1-tk reporter gene expression in vivo using PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(1):96-105.
2000: D M Araujo; Simon R Cherry; Keith J Tatsukawa; Tatsushi Toyokuni; Harley I Kornblum
Deficits in striatal dopamine D(2) receptors and energy metabolism detected by in vivo microPET imaging in a rat model of Huntington's disease.
Experimental neurology 2000;166(2):287-97.
2000: Duncan C MacLaren; Tatsushi Toyokuni; Simon R Cherry; Jorge R Barrio; Michael E Phelps; Harvey R Herschman; Sanjiv S Gambhir
PET imaging of transgene expression.
Biological psychiatry 2000;48(5):337-48.
2000: Y Yu; Alexander Annala; Jorge R Barrio; Tatsushi Toyokuni; Nagichettiar Satyamurthy; Mohammad Namavari; Simon R Cherry; Michael E Phelps; Harvey R Herschman; Sanjiv S Gambhir
Quantification of target gene expression by imaging reporter gene expression in living animals.
Nature medicine 2000;6(8):933-7.
2000: Anna M Wu; Paul J Yazaki; S w Tsai; Khoi Nguyen; Anne-Line Anderson; D W McCarthy; M J Welch; John E Shively; Lawrence E Williams; Andrew Raubitschek; Jeffrey Y C Wong; Tatsushi Toyokuni; Michael E Phelps; Sanjiv S Gambhir
High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8495-500.
2000: Harvey R Herschman; Duncan C MacLaren; Meera Iyer; Mohammad Namavari; K Bobinski; Leeta Alison Green; Lily Wu; Arnold J Berk; Tatsushi Toyokuni; Jorge R Barrio; Simon R Cherry; Michael E Phelps; E P Sandgren; Sanjiv S Gambhir
Seeing is believing: non-invasive, quantitative and repetitive imaging of reporter gene expression in living animals, using positron emission tomography.
Journal of neuroscience research 2000;59(6):699-705.
2000: Mohammad Namavari; Jorge R Barrio; Tatsushi Toyokuni; Sanjiv S Gambhir; Simon R Cherry; Harvey R Herschman; Michael E Phelps; N Satyamurthy1
Synthesis of 8-[(18)F]fluoroguanine derivatives: in vivo probes for imaging gene expression with positron emission tomography.
Nuclear medicine and biology 2000;27(2):157-62.
2000: Sanjiv S Gambhir; Harvey R Herschman; Simon R Cherry; Jorge R Barrio; Nagichettiar Satyamurthy; Tatsushi Toyokuni; Michael E Phelps; Steven M Larson; Julius Balatoni; Ronald Finn; Michel Sadelain; Juri Gelovani Tjuvajev; Ronald Blasberg
Imaging transgene expression with radionuclide imaging technologies.
Neoplasia (New York, N.Y.) 2000;2(1-2):118-38.
1999: Duncan C MacLaren; Sanjiv S Gambhir; Nagichettiar Satyamurthy; Jorge R Barrio; S Sharfstein; Tatsushi Toyokuni; Lily Wu; Arnold J Berk; Simon R Cherry; Michael E Phelps; Harvey R Herschman
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals.
Gene therapy 1999;6(5):785-91.
1998: D Pan; Sanjiv S Gambhir; Tatsushi Toyokuni; Meera Iyer; N Acharya; Michael E Phelps; Jorge R Barrio
Rapid synthesis of a 5'-fluorinated oligodeoxy-nucleotide: a model antisense probe for use in imaging with positron emission tomography (PET).
Bioorganic & medicinal chemistry letters 1998;8(11):1317-20.

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