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Hans Trachsel

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Chemicals & Drugs

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Saccharomyces cerevisiae

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Publications

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Patrick Schütz; Mario Bumann; Anselm Erich Oberholzer; Christoph Bieniossek; Hans Trachsel; Michael Altmann; Ulrich Baumann
Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions.
Mario Bumann; Siamak Djafarzadeh; Anselm Erich Oberholzer; Peter Bigler; Michael Altmann; Hans Trachsel; Ulrich Baumann
Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits.
Valérie Vergé; Martin Vonlanthen; Jean-Michel Masson; Hans Trachsel; Michael Altmann
Localization of a promoter in the putative internal ribosome entry site of the Saccharomyces cerevisiae TIF4631 gene.

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All Publications

2008: Patrick Schütz; Mario Bumann; Anselm Erich Oberholzer; Christoph Bieniossek; Hans Trachsel; Michael Altmann; Ulrich Baumann
Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9564-9.
2004: Mario Bumann; Siamak Djafarzadeh; Anselm Erich Oberholzer; Peter Bigler; Michael Altmann; Hans Trachsel; Ulrich Baumann
Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits.
The Journal of biological chemistry 2004;279(35):37087-94.
2004: Valérie Vergé; Martin Vonlanthen; Jean-Michel Masson; Hans Trachsel; Michael Altmann
Localization of a promoter in the putative internal ribosome entry site of the Saccharomyces cerevisiae TIF4631 gene.
RNA (New York, N.Y.) 2004;10(2):277-86.
2003: Catherine Berset; Andreas Zurbriggen; Siamak Djafarzadeh; Michael Altmann; Hans Trachsel
RNA-binding activity of translation initiation factor eIF4G1 from Saccharomyces cerevisiae.
RNA (New York, N.Y.) 2003;9(7):871-80.
2003: Anton A Komar; Thierry Lesnik; Christophe Cullin; William C Merrick; Hans Trachsel; Michael Altmann
Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells.
The EMBO journal 2003;22(5):1199-209.
2001: D Dominguez; E Kislig; Michael Altmann; Hans Trachsel
Structural and functional similarities between the central eukaryotic initiation factor (eIF)4A-binding domain of mammalian eIF4G and the eIF4A-binding domain of yeast eIF4G.
The Biochemical journal 2001;355(Pt 1):223-30.
1999: D Dominguez; Michael Altmann; J Benz; Ulrich Baumann; Hans Trachsel
Interaction of translation initiation factor eIF4G with eIF4A in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1999;274(38):26720-6.
1999: J Benz; Hans Trachsel; Ulrich Baumann
Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae--the prototype of the DEAD box protein family.
Structure (London, England : 1993) 1999;7(6):671-9.
1999: P Danaie; Michael Altmann; Michael N Hall; Hans Trachsel; Stephen Helliwell
CLN3 expression is sufficient to restore G1-to-S-phase progression in Saccharomyces cerevisiae mutants defective in translation initiation factor eIF4E.
The Biochemical journal 1999;340 ( Pt 1)():135-41.
1998: P P Mueller; P Grueter; A G Hinnebusch; Hans Trachsel
A ribosomal protein is required for translational regulation of GCN4 mRNA. Evidence for involvement of the ribosome in eIF2 recycling.
The Journal of biological chemistry 1998;273(49):32870-7.
1998: N Niederberger; Hans Trachsel; Michael Altmann
The RNA recognition motif of yeast translation initiation factor Tif3/eIF4B is required but not sufficient for RNA strand-exchange and translational activity.
RNA (New York, N.Y.) 1998;4(10):1259-67.
1998: Catherine Berset; Hans Trachsel; Michael Altmann
The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4264-9.
1997: Michael Altmann; Hans Trachsel
Translation initiation factor-dependent extracts from yeast Saccharomyces cerevisiae.
Methods (San Diego, Calif.) 1997;11(4):343-52.
1997: Michael Altmann; N Schmitz; Catherine Berset; Hans Trachsel
A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E.
The EMBO journal 1997;16(5):1114-21.
1995: Michael Altmann; B Wittmer; N Méthot; Nahum Sonenberg; Hans Trachsel
The Saccharomyces cerevisiae translation initiation factor Tif3 and its mammalian homologue, eIF-4B, have RNA annealing activity.
The EMBO journal 1995;14(15):3820-7.
1995: P Danaie; B Wittmer; Michael Altmann; Hans Trachsel
Isolation of a protein complex containing translation initiation factor Prt1 from Saccharomyces cerevisiae.
The Journal of biological chemistry 1995;270(9):4288-92.
1994: G W Owttrim; T Mandel; Hans Trachsel; A A Thomas; Cris Kuhlemeier
Characterization of the tobacco eIF-4A gene family.
Plant molecular biology 1994;26(6):1747-57.
1994: Michael Altmann; Hans Trachsel
The yeast Saccharomyces cerevisiae system: a powerful tool to study the mechanism of protein synthesis initiation in eukaryotes.
Biochimie 1994;76(9):853-61.
1993: Michael Altmann; Hans Trachsel
Regulation of translation initiation and modulation of cellular physiology.
Trends in biochemical sciences 1993;18(11):429-32.
1993: Michael Altmann; P P Müller; B Wittmer; F Ruchti; S Lanker; Hans Trachsel
A Saccharomyces cerevisiae homologue of mammalian translation initiation factor 4B contributes to RNA helicase activity.
The EMBO journal 1993;12(10):3997-4003.
1993: C Goyer; Michael Altmann; Han S Lee; A Blanc; Mohanish Deshmukh; John L Woolford; Hans Trachsel; Nahum Sonenberg
TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.
Molecular and cellular biology 1993;13(8):4860-74.
1992: S Lanker; P P Müller; Michael Altmann; C Goyer; Nahum Sonenberg; Hans Trachsel
Interactions of the eIF-4F subunits in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1992;267(29):21167-71.
1992: S Lanker; J L Bushman; Alan G Hinnebusch; Hans Trachsel; P P Mueller
Autoregulation of the yeast lysyl-tRNA synthetase gene GCD5/KRS1 by translational and transcriptional control mechanisms.
Cell 1992;70(4):647-57.
1992: S Blum; S R Schmid; A Pause; P Buser; P Linder; Nahum Sonenberg; Hans Trachsel
ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7664-8.
1990: Michael Altmann; S Blum; J Pelletier; Nahum Sonenberg; T M Wilson; Hans Trachsel
Translation initiation factor-dependent extracts from Saccharomyces cerevisiae.
Biochimica et biophysica acta 1990;1050(1-3):155-9.
1990: M Jaramillo; Karen S Browning; T E Dever; S Blum; Hans Trachsel; William C Merrick; J M Ravel; Nahum Sonenberg
Translation initiation factors that function as RNA helicases from mammals, plants and yeast.
Biochimica et biophysica acta 1990;1050(1-3):134-9.
1990: A Prat; S R Schmid; P Buser; S Blum; Hans Trachsel; P J Nielsen; P Linder
Expression of translation initiation factor 4A from yeast and mouse in Saccharomyces cerevisiae.
Biochimica et biophysica acta 1990;1050(1-3):140-5.
1990: P P Müller; Hans Trachsel
Translation and regulation of translation in the yeast Saccharomyces cerevisiae.
European journal of biochemistry / FEBS 1990;191(2):257-61.
1990: Michael Altmann; S Blum; T M Wilson; Hans Trachsel
The 5'-leader sequence of tobacco mosaic virus RNA mediates initiation-factor-4E-independent, but still initiation-factor-4A-dependent translation in yeast extracts.
Gene 1990;91(1):127-9.
1989: Michael Altmann; Nahum Sonenberg; Hans Trachsel
Translation in Saccharomyces cerevisiae: initiation factor 4E-dependent cell-free system.
Molecular and cellular biology 1989;9(10):4467-72.
1989: Michael Altmann; M Krieger; Hans Trachsel
Nucleotide sequence of the gene encoding a 20 kDa protein associated with the cap binding protein eIF-4E from Saccharomyces cerevisiae.
Nucleic acids research 1989;17(18):7520.
1989: F Rozen; Jerry Pelletier; Hans Trachsel; Nahum Sonenberg
A lysine substitution in the ATP-binding site of eucaryotic initiation factor 4A abrogates nucleotide-binding activity.
Molecular and cellular biology 1989;9(9):4061-3.
1989: Michael Altmann; Hans Trachsel
Altered mRNA cap recognition activity of initiation factor 4E in the yeast cell cycle division mutant cdc33.
Nucleic acids research 1989;17(15):5923-31.
1989: P P Müller; Hans Trachsel; P Linder
Genetic localization of the Saccharomyces cerevisiae genes tif1 and tif2.
Current genetics 1989;16(2):127-8.
1989: S Blum; M Mueller; S R Schmid; P Linder; Hans Trachsel
Translation in Saccharomyces cerevisiae: initiation factor 4A-dependent cell-free system.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6043-6.
1989: Michael Altmann; P P Müller; J Pelletier; Nahum Sonenberg; Hans Trachsel
A mammalian translation initiation factor can substitute for its yeast homologue in vivo.
The Journal of biological chemistry 1989;264(21):12145-7.
1989: C Goyer; Michael Altmann; Hans Trachsel; Nahum Sonenberg
Identification and characterization of cap-binding proteins from yeast.
The Journal of biological chemistry 1989;264(13):7603-10.
1989: T Mandel; Hans Trachsel
Yeast, Saccharomyces cerevisiae, cell-free translation: the inhibition of translation by high temperature is reversible.
Biochimica et biophysica acta 1989;1007(1):80-3.
1988: Michael Altmann; I Edery; Hans Trachsel; Nahum Sonenberg
Site-directed mutagenesis of the tryptophan residues in yeast eukaryotic initiation factor 4E. Effects on cap binding activity.
The Journal of biological chemistry 1988;263(33):17229-32.
1987: Michael Altmann; C Handschin; Hans Trachsel
mRNA cap-binding protein: cloning of the gene encoding protein synthesis initiation factor eIF-4E from Saccharomyces cerevisiae.
Molecular and cellular biology 1987;7(3):998-1003.
1985: Michael Altmann; I Edery; Nahum Sonenberg; Hans Trachsel
Purification and characterization of protein synthesis initiation factor eIF-4E from the yeast Saccharomyces cerevisiae.
Biochemistry 1985;24(22):6085-9.
1983: I Edery; M Hümbelin; A Darveau; K A Lee; S Milburn; J W Hershey; Hans Trachsel; Nahum Sonenberg
Involvement of eukaryotic initiation factor 4A in the cap recognition process.
The Journal of biological chemistry 1983;258(18):11398-403.
1982: A Zumbé; C Stähli; Hans Trachsel
Association of a Mr 50,000 cap-binding protein with the cytoskeleton in baby hamster kidney cells.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(9):2927-31.
1982: Hans Trachsel; A Zumbé; C Stähli; M Hümbelin; N Sonenberg
Association of an Mr 50,000 cap binding protein with the cytoskeleton in BHK cells.
Biochemical Society symposium 1982;47():145-61.
1981: Nahum Sonenberg; D Guertin; D Cleveland; Hans Trachsel
Probing the function of the eucaryotic 5' cap structure by using a monoclonal antibody directed against cap-binding proteins.
Cell 1981;27(3 Pt 2):563-72.