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Frank Traganos

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Physiology

Cell Cycle

Chemicals & Drugs

Anatomy

Procedures

Flow Cytometry

Phenomena

Phosphorylation

Disorders

DNA Damage

Concepts & Ideas

S Phase

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Co-Publications
Name
106
Darzynkiewicz, Zbigniew
27
Halicka, Dorota
19
Huang, Xuan
17
Tanaka, Toshiki
12
Juan, Gloria
12
Dai, Wei
10
Seiter, Karen
10
Kurose, Akira
8
Li, X
8
Ardelt, Barbara
7
Bedner, Elzbieta
7
Albino, Anthony
5
Hsieh, Tze-Chen
5
Gorczyca, Wojciech
5
Feldman, Eric

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Publications

TOP 3
Zhao Hong; Albino Anthony P; Jorgensen Ellen; Traganos Frank; Darzynkiewicz Zbigniew
DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry.
Albino Anthony P; Jorgensen Ellen D; Rainey Patrick; Gillman Gene; Clark T Jeffrey; Gietl Diana; Zhao Hong; Traganos Frank; Darzynkiewicz Zbigniew
gammaH2AX: A potential DNA damage response biomarker for assessing toxicological risk of tobacco products.
Halicka H Dorota; Smart Daniel J; Traganos Frank; Williams Gary M; Darzynkiewicz Zbigniew
Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status.

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All Publications

2009: Zhao Hong; Albino Anthony P; Jorgensen Ellen; Traganos Frank; Darzynkiewicz Zbigniew
DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2009;75(10):840-7.
2009: Albino Anthony P; Jorgensen Ellen D; Rainey Patrick; Gillman Gene; Clark T Jeffrey; Gietl Diana; Zhao Hong; Traganos Frank; Darzynkiewicz Zbigniew
gammaH2AX: A potential DNA damage response biomarker for assessing toxicological risk of tobacco products.
Mutation research 2009;678(1):43-52.
2009: Halicka H Dorota; Smart Daniel J; Traganos Frank; Williams Gary M; Darzynkiewicz Zbigniew
Fluoroquinolones lower constitutive H2AX and ATM phosphorylation in TK6 lymphoblastoid cells via modulation of the intracellular redox status.
Pharmacological reports : PR 2009;61(4):711-8.
2009: Halicka H Dorota; Zhao Hong; Podhorecka Monika; Traganos Frank; Darzynkiewicz Zbigniew
Cytometric detection of chromatin relaxation, an early reporter of DNA damage response.
Cell cycle (Georgetown, Tex.) 2009;8(14):2233-7.
2009: Halicka H Dorota; Ozkaynak M Fevzi; Levendoglu-Tugal Oya; Sandoval Claudio; Seiter Karen; Kajstura Malgorzata; Traganos Frank; Jayabose Somasunadaram; Darzynkiewicz Zbigniew
DNA damage response as a biomarker in treatment of leukemias.
Cell cycle (Georgetown, Tex.) 2009;8(11):1720-4.
2009: Zhao Hong; Traganos Frank; Dobrucki Jurek; Wlodkowic Donald; Darzynkiewicz Zbigniew
Induction of DNA damage response by the supravital probes of nucleic acids.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2009;75(6):510-9.
2009: Sato Yuichi; Kurose Akira; Ogawa Akira; Ogasawara Kuniaki; Traganos Frank; Darzynkiewicz Zbigniew; Sawai Takashi
Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide.
Cancer biology & therapy 2009;8(5):452-7.
2009: Tanaka Toshiki; Halicka Dorota; Traganos Frank; Darzynkiewicz Zbigniew
Cytometric analysis of DNA damage: phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs).
Methods in molecular biology (Clifton, N.J.) 2009;523():161-8.
2008: Zhao Hong; Traganos Frank; Darzynkiewicz Zbigniew
Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation.
Cell cycle (Georgetown, Tex.) 2008;7(19):3048-55.
2008: Zhao Hong; Traganos Frank; Darzynkiewicz Zbigniew
Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(6):480-9.
2008: Smart Daniel J; Halicka H Dorota; Schmuck Gabriele; Traganos Frank; Darzynkiewicz Zbigniew; Williams Gary M
Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone.
Mutation research 2008;641(1-2):43-7.
2008: Zhao Hong; Traganos Frank; Albino Anthony P; Darzynkiewicz Zbigniew
Oxidative stress induces cell cycle-dependent Mre11 recruitment, ATM and Chk2 activation and histone H2AX phosphorylation.
Cell cycle (Georgetown, Tex.) 2008;7(10):1490-5.
2008: Chen Sophie; Gao Jian; Halicka H Dorota; Traganos Frank; Darzynkiewicz Zbigniew
Down-regulation of androgen-receptor and PSA by phytochemicals.
International journal of oncology 2008;32(2):405-11.
2008: Smart Daniel J; Halicka H Dorota; Traganos Frank; Darzynkiewicz Zbigniew; Williams Gary M
Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation.
Cancer biology & therapy 2008;7(1):113-9.
2007: Hsieh Tze-Chen; Traganos Frank; Darzynkiewicz Zbigniew; Wu Joseph M
The 2,6-disubstituted purine reversine induces growth arrest and polyploidy in human cancer cells.
International journal of oncology 2007;31(6):1293-300.
2007: Zhao Hong; Tanaka Toshiki; Halicka H Dorota; Traganos Frank; Zarebski Miroslaw; Dobrucki Jurek; Darzynkiewicz Zbigniew
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(11):905-14.
2007: Tanaka Toshiki; Huang Xuan; Halicka H Dorota; Zhao Hong; Traganos Frank; Albino Anthony P; Dai Wei; Darzynkiewicz Zbigniew
Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(9):648-61.
2007: Tanaka Toshiki; Halicka H Dorota; Traganos Frank; Seiter Karen; Darzynkiewicz Zbigniew
Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase.
Cell cycle (Georgetown, Tex.) 2007;6(3):371-6.
2007: Tanaka T; Kajstura M; Halicka H D; Traganos F; Darzynkiewicz Z
Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes.
Cell proliferation 2007;40(1):1-13.
2007: Tanaka Toshiki; Huang Xuan; Jorgensen Ellen; Gietl Diana; Traganos Frank; Darzynkiewicz Zbigniew; Albino Anthony P
ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke.
BMC cell biology 2007;8():26.
2006: Tanaka Toshiki; Halicka H Dorota; Traganos Frank; Darzynkiewicz Zbigniew
Phosphorylation of histone H2AX on Ser 139 and activation of ATM during oxidative burst in phorbol ester-treated human leukocytes.
Cell cycle (Georgetown, Tex.) 2006;5(22):2671-5.
2006: Tanaka Toshiki; Halicka H Dorota; Huang Xuan; Traganos Frank; Darzynkiewicz Zbigniew
Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants.
Cell cycle (Georgetown, Tex.) 2006;5(17):1940-5.
2006: Tanaka T; Kurose A; Huang X; Traganos F; Dai W; Darzynkiewicz Z
Extent of constitutive histone H2AX phosphorylation on Ser-139 varies in cells with different TP53 status.
Cell proliferation 2006;39(4):313-23.
2006: Tanaka Toshiki; Kurose Akira; Halicka H Dorota; Huang Xuan; Traganos Frank; Darzynkiewicz Zbigniew
Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species.
Cell cycle (Georgetown, Tex.) 2006;5(15):1669-74.
2006: Huang Xuan; Tanaka Toshiki; Kurose Akira; Traganos Frank; Darzynkiewicz Zbigniew
Constitutive histone H2AX phosphorylation on Ser-139 in cells untreated by genotoxic agents is cell-cycle phase specific and attenuated by scavenging reactive oxygen species.
International journal of oncology 2006;29(2):495-501.
2006: Huang Xuan; Kurose Akira; Tanaka Toshiki; Traganos Frank; Dai Wei; Darzynkiewicz Zbigniew
Activation of ATM and histone H2AX phosphorylation induced by mitoxantrone but not by topotecan is prevented by the antioxidant N-acetyl-L-cysteine.
Cancer biology & therapy 2006;5(8):959-64.
2006: Albino Anthony P; Huang Xuan; Jorgensen Ellen D; Gietl Diana; Traganos Frank; Darzynkiewicz Zbigniew
Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals.
International journal of oncology 2006;28(6):1491-505.
2006: Kurose A; Tanaka T; Huang X; Traganos F; Darzynkiewicz Z
Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage.
Cell proliferation 2006;39(3):231-40.
2006: Fang Y; Liu T; Wang X; Yang Y-M; Deng H; Kunicki J; Traganos F; Darzynkiewicz Z; Lu L; Dai W
BubR1 is involved in regulation of DNA damage responses.
Oncogene 2006;25(25):3598-605.
2006: Tanaka Toshiki; Kurose Akira; Halicka H Dorota; Traganos Frank; Darzynkiewicz Zbigniew
2-deoxy-D-glucose reduces the level of constitutive activation of ATM and phosphorylation of histone H2AX.
Cell cycle (Georgetown, Tex.) 2006;5(8):878-82.
2006: Huang Xuan; Kurose Akira; Tanaka Toshiki; Traganos Frank; Dai Wei; Darzynkiewicz Zbigniew
Sequential phosphorylation of Ser-10 on histone H3 and ser-139 on histone H2AX and ATM activation during premature chromosome condensation: relationship to cell-cycle phase and apoptosis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(4):222-9.
2006: Kurose Akira; Tanaka Toshiki; Huang Xuan; Traganos Frank; Dai Wei; Darzynkiewicz Zbigniew
Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(4):212-21.
2006: Gupte Rakhee S; Sampson Valerie; Traganos Frank; Darzynkiewicz Zbigniew; Lee Marietta Y W T
Cyclic AMP regulates the expression and nuclear translocation of RFC40 in MCF7 cells.
Experimental cell research 2006;312(6):796-806.
2006: Gupte Rakhee S; Traganos Frank; Darzynkiewicz Zbigniew; Lee Marietta Y W T
Phosphorylation of RIalpha by cyclin-dependent kinase CDK 2/cyclin E modulates the dissociation of the RIalpha-RFC40 complex.
Cell cycle (Georgetown, Tex.) 2006;5(6):653-60.
2005: Kurose Akira; Tanaka Toshiki; Huang Xuan; Halicka H Dorota; Traganos Frank; Dai Wei; Darzynkiewicz Zbigniew
Assessment of ATM phosphorylation on Ser-1981 induced by DNA topoisomerase I and II inhibitors in relation to Ser-139-histone H2AX phosphorylation, cell cycle phase, and apoptosis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2005;68(1):1-9.
2005: Yang Yang-Ming; Jhanwar-Uniyal Meena; Schwartz Joel; Conaway C Clifford; Halicka H Dorota; Traganos Frank; Chung Fung-Lung
N-acetylcysteine conjugate of phenethyl isothiocyanate enhances apoptosis in growth-stimulated human lung cells.
Cancer research 2005;65(18):8538-47.
2005: Huang Xuan; Halicka H Dorota; Traganos Frank; Tanaka Toshiki; Kurose Akira; Darzynkiewicz Zbigniew
Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis.
Cell proliferation 2005;38(4):223-43.
2005: Gupte Rakhee S; Pozarowski Piotr; Grabarek Jerzy; Traganos Frank; Darzynkiewicz Zbigniew; Lee Marietta Y W T
RIalpha influences cellular proliferation in cancer cells by transporting RFC40 into the nucleus.
Cancer biology & therapy 2005;4(4):429-37.
2005: Chen Sophie; Gao Jian; Halicka H Dorota; Huang Xuan; Traganos Frank; Darzynkiewicz Zbigniew
The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage.
International journal of oncology 2005;26(3):579-88.
2005: Halicka H Dorota; Huang Xuan; Traganos Frank; King Malcolm A; Dai Wei; Darzynkiewicz Zbigniew
Histone H2AX phosphorylation after cell irradiation with UV-B: relationship to cell cycle phase and induction of apoptosis.
Cell cycle (Georgetown, Tex.) 2005;4(2):339-45.
2004: Huang Xuan; King Malcolm A; Halicka H Dorota; Traganos Frank; Okafuji Masaki; Darzynkiewicz Zbigniew
Histone H2AX phosphorylation induced by selective photolysis of BrdU-labeled DNA with UV light: relation to cell cycle phase.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004;62(1):1-7.
2004: Olson Susan; Oeckler Richard; Li Xinmei; Du Litong; Traganos Frank; Zhao Xiangmin; Burke-Wolin Theresa
Angiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor.
American journal of physiology. Lung cellular and molecular physiology 2004;287(3):L559-68.
2004: Albino A P; Huang X; Jorgensen E; Yang J; Gietl D; Traganos F; Darzynkiewicz Z
Induction of H2AX phosphorylation in pulmonary cells by tobacco smoke: a new assay for carcinogens.
Cell cycle (Georgetown, Tex.) 2004;3(8):1062-8.
2004: Zhu Xin-Hua; Nguyen Hoang; Halicka H Dorota; Traganos Frank; Koff Andrew
Noncatalytic requirement for cyclin A-cdk2 in p27 turnover.
Molecular and cellular biology 2004;24(13):6058-66.
2004: Huang Xuan; Ruan Qin; Fang Yuqiang; Traganos Frank; Darzynkiewicz Zbigniew; Dai Wei
Physical and functional interactions between mitotic kinases during polyploidization and megakaryocytic differentiation.
Cell cycle (Georgetown, Tex.) 2004;3(7):946-51.
2004: Yeh Raymond K; Chen Jie; Williams Jennie L; Baluch Mehdi; Hundley Thomas R; Rosenbaum Raphael E; Kalala Srinivas; Traganos Frank; Benardini Francesca; del Soldato Piero; Kashfi Khosrow; Rigas Basil
NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property?
Biochemical pharmacology 2004;67(12):2197-205.
2004: Huang Xuan; Okafuji Masaki; Traganos Frank; Luther Ed; Holden Elena; Darzynkiewicz Zbigniew
Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004;58(2):99-110.
2004: Traganos Frank
Cycling without cyclins.
Cell cycle (Georgetown, Tex.) 2004;3(1):32-4.
2004: Traganos Frank
Mechanism of antitumor drug action assessed by cytometry.
Methods in cell biology 2004;75():257-305.
2003: Huang Xuan; Traganos Frank; Darzynkiewicz Zbigniew
DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis.
Cell cycle (Georgetown, Tex.) 2003;2(6):614-9.
2003: Darzynkiewicz Zbigniew; Juan Gloria; Traganos Frank
Cytometry of cell cycle regulatory proteins.
Progress in cell cycle research 2003;5():533-42.
2002: Kashfi Khosrow; Ryan Yassir; Qiao Leon L; Williams Jennie L; Chen Jie; Del Soldato Piero; Traganos Frank; Rigas Basil;
Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect.
The Journal of pharmacology and experimental therapeutics 2002;303(3):1273-82.
2002: Blagosklonny Mikhail V; Robey Robert; Sackett Dan L; Du Litong; Traganos Frank; Darzynkiewicz Zbigniew; Fojo Tito; Bates Susan E
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.
Molecular cancer therapeutics 2002;1(11):937-41.
2002: Xie Suqing; Wang Qi; Luo Lu; Ruan Qin; Liu Tongyi; Jhanwar-Uniyal Meena; Darzynkiewicz Zbigniew; Traganos Frank; Dai Wei
Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen species.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(9):957-63.
2002: Dai Wei; Wang Qi; Traganos Frank
Polo-like kinases and centrosome regulation.
Oncogene 2002;21(40):6195-200.
2002: Li Volti Giovanni; Wang Jishi; Traganos Frank; Kappas Attallah; Abraham Nader G
Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression.
Biochemical and biophysical research communications 2002;296(5):1077-82.
2002: Hsieh Tze-Chen; Xiong Wen; Traganos Frank; Darzynkiewicz Zbigniew; Wu Joseph M
Effects of PC-SPES on proliferation and expression of AR/PSA in androgen-responsive LNCaP cells are independent of estradiol.
Anticancer research 2002;22(4):2051-60.
2002: Halicka H Dorota; Smolewski Piotr; Darzynkiewicz Zbigniew; Dai Wei; Traganos Frank
Arsenic trioxide arrests cells early in mitosis leading to apoptosis.
Cell cycle (Georgetown, Tex.) 2002;1(3):201-9.
2002: Wang Qi; Xie Suqing; Chen Jie; Fukasawa Kenji; Naik Ulhas; Traganos Frank; Darzynkiewicz Zbigniew; Jhanwar-Uniyal Meena; Dai Wei
Cell cycle arrest and apoptosis induced by human Polo-like kinase 3 is mediated through perturbation of microtubule integrity.
Molecular and cellular biology 2002;22(10):3450-9.
2001: Chen S; Ruan Q; Bedner E; Deptala A; Wang X; Hsieh T C; Traganos F; Darzynkiewicz Z
Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines.
Cell proliferation 2001;34(5):293-304.
2001: Du L; Smolewski P; Bedner E; Traganos F; Darzynkiewicz Z
Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor.
International journal of oncology 2001;19(4):811-9.
2001: Ardelt B; Kunicki J; Traganos F; Darzynkiewicz Z
Chlorophyllin protects cells from the cytostatic and cytotoxic effects of quinacrine mustard but not of nitrogen mustard.
International journal of oncology 2001;18(4):849-53.
2001: Bedner E; Du L; Traganos F; Darzynkiewicz Z
Caffeine dissociates complexes between DNA and intercalating dyes: application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometry.
Cytometry 2001;43(1):38-45.
2001: Darzynkiewicz Z; Juan G; Traganos F
Assaying drug-induced apoptosis.
Methods in molecular biology (Clifton, N.J.) 2001;95():241-54.
2001: Traganos F; Juan G; Darzynkiewicz Z
Cell-cycle analysis of drug-treated cells.
Methods in molecular biology (Clifton, N.J.) 2001;95():229-40.
2001: Darzynkiewicz Z; Bedner E; Traganos F
Difficulties and pitfalls in analysis of apoptosis.
Methods in cell biology 2001;63():527-46.
2001: Juan G; Traganos F; Darzynkiewicz Z
Methods to identify mitotic cells by flow cytometry.
Methods in cell biology 2001;63():343-54.
2000: Nair J; Traganos F; Tse-Dinh Y C
Differential effect of camptothecin treatment on topoisomerase II alpha expression in ML-1 and HL-60 leukemia cell lines.
Anticancer research 2000;20(6B):4183-8.
2000: DiPietrantonio A M; Hsieh T C; Juan G; Traganos F; Darzynkiewicz Z; Wu J M
Fenretinide-induced caspase 3 activity involves increased protein stability in a mechanism distinct from reactive oxygen species elevation.
Cancer research 2000;60(16):4331-5.
2000: Albino A P; Juan G; Traganos F; Reinhart L; Connolly J; Rose D P; Darzynkiewicz Z
Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation.
Cancer research 2000;60(15):4139-45.
2000: Feldman E J; Seiter K; Traganos F; Darzynkiewicz Z; Goff H; Pozzuoli M; Baskind P; Santos S; Ahmed T
Phase II evaluation of a high-dose mitoxantrone based induction regimen in untreated adults with acute myeloid leukemia.
Leukemia & lymphoma 2000;38(3-4):309-15.
2000: Lin C W; Darzynkiewicz Z; Li X; Traganos F; Bedner E; Tse-Dinh Y C
Differential expression of human topoisomerase IIIalpha during the cell cycle progression in HL-60 leukemia cells and human peripheral blood lymphocytes.
Experimental cell research 2000;256(1):225-36.
2000: Seiter K; Feldman E J; Dorota Halicka H; Deptala A; Traganos F; Burke H B; Hoang A; Goff H; Pozzuoli M; Kancherla R; Darzynkiewicz Z; Ahmed T
Clinical and laboratory evaluation of all-trans retinoic acid modulation of chemotherapy in patients with acute myelogenous leukaemia.
British journal of haematology 2000;108(1):40-7.
2000: Nair J S; Kancherla R; Seiter K; Traganos F; Tse-Dinh Y C
Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies.
Annals of the New York Academy of Sciences 2000;922():326-9.
1999: Deptala A; Li X; Bedner E; Cheng W; Traganos F; Darzynkiewicz Z
Differences in induction of p53, p21WAF1 and apoptosis in relation to cell cycle phase of MCF-7 cells treated with camptothecin.
International journal of oncology 1999;15(5):861-71.
1999: Hsieh T C; Burfeind P; Laud K; Backer J M; Traganos F; Darzynkiewicz Z; Wu J M
Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials.
International journal of oncology 1999;15(2):245-52.
1999: Juan G; Traganos F; Darzynkiewicz Z
Histone H3 phosphorylation in human monocytes and during HL-60 cell differentiation.
Experimental cell research 1999;246(1):212-20.
1998: Juan G; Traganos F; James W M; Ray J M; Roberge M; Sauve D M; Anderson H; Darzynkiewicz Z
Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis.
Cytometry 1998;32(2):71-7.
1998: Darzynkiewicz Z; Bedner E; Traganos F; Murakami T
Critical aspects in the analysis of apoptosis and necrosis.
Human cell : official journal of Human Cell Research Society 1998;11(1):3-12.
1998: Darzynkiewicz Z; Traganos F
Measurement of apoptosis.
Advances in biochemical engineering/biotechnology 1998;62():33-73.
1997: Haider S R; Juan G; Traganos F; Darzynkiewicz Z
Immunoseparation and immunodetection of nucleic acids labeled with halogenated nucleotides.
Experimental cell research 1997;234(2):498-506.
1997: Vibhakar R; Juan G; Traganos F; Darzynkiewicz Z; Finger L R
Activation-induced expression of human programmed death-1 gene in T-lymphocytes.
Experimental cell research 1997;232(1):25-8.
1997: Darzynkiewicz Z; Juan G; Li X; Gorczyca W; Murakami T; Traganos F
Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis).
Cytometry 1997;27(1):1-20.
1997: Seiter K; Feldman E J; Halicka H D; Traganos F; Darzynkiewicz Z; Lake D; Ahmed T
Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(1):44-51.
1997: Halicka H D; Seiter K; Feldman E J; Traganos F; Mittelman A; Ahmed T; Darzynkiewicz Z
Cell cycle specificity of apoptosis during treatment of leukaemias.
Apoptosis : an international journal on programmed cell death 1997;2(1):25-39.
1996: Traganos F; Seiter K; Feldman E; Halicka H D; Darzynkiewicz Z
Induction of apoptosis by camptothecin and topotecan.
Annals of the New York Academy of Sciences 1996;803():101-10.
1996: Darzynkiewicz Z; Bruno S; Del Bino G; Traganos F
The cell cycle effects of camptothecin.
Annals of the New York Academy of Sciences 1996;803():93-100.
1996: Darzynkiewicz Z; Gong J; Juan G; Ardelt B; Traganos F
Cytometry of cyclin proteins.
Cytometry 1996;25(1):1-13.
1996: Juan G; Gong J; Traganos F; Darzynkiewicz Z
Unscheduled expression of cyclins D1 and D3 in human tumour cell lines.
Cell proliferation 1996;29(5):259-66.
1996: Hara S; Halicka H D; Bruno S; Gong J; Traganos F; Darzynkiewicz Z
Effect of protease inhibitors on early events of apoptosis.
Experimental cell research 1996;223(2):372-84.
1995: Gong J; Traganos F; Darzynkiewicz Z
Growth imbalance and altered expression of cyclins B1, A, E, and D3 in MOLT-4 cells synchronized in the cell cycle by inhibitors of DNA replication.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(11):1485-93.
1995: Seiter K; Feldman E J; Traganos F; Li X; Halicka H D; Darzynkiewicz Z; Lederman C A; Romero M B; Ahmed T
Evaluation of in vivo induction of apoptosis in patients with acute leukemia treated on a phase I study of paclitaxel.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(11):1961-6.
1995: Li X; James W M; Traganos F; Darzynkiewicz Z
Application of biotin, digoxigenin or fluorescein conjugated deoxynucleotides to label DNA strand breaks for analysis of cell proliferation and apoptosis using flow cytometry.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 1995;70(5):234-42.
1995: Gong J; Traganos F; Darzynkiewicz Z
Discrimination of G2 and mitotic cells by flow cytometry based on different expression of cyclins A and B1.
Experimental cell research 1995;220(1):226-31.
1995: Bhatia U; Danishefsky K; Traganos F; Darzynkiewicz Z
Induction of apoptosis and cell cycle-specific change in expression of p53 in normal lymphocytes and MOLT-4 leukemic cells by nitrogen mustard.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(8):873-80.
1995: Bhatia U; Traganos F; Darzynkiewicz Z
Induction of cell differentiation potentiates apoptosis triggered by prior exposure to DNA-damaging drugs.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(8):937-44.
1995: Murakami T; Li X; Gong J; Bhatia U; Traganos F; Darzynkiewicz Z
Induction of apoptosis by 5-azacytidine: drug concentration-dependent differences in cell cycle specificity.
Cancer research 1995;55(14):3093-8.
1995: Li X; Traganos F; Melamed M R; Darzynkiewicz Z
Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.
Cytometry 1995;20(2):172-80.
1995: Gong J; Traganos F; Darzynkiewicz Z
Threshold expression of cyclin E but not D type cyclins characterizes normal and tumour cells entering S phase.
Cell proliferation 1995;28(6):337-46.
1995: Gong J; Bhatia U; Traganos F; Darzynkiewicz Z
Expression of cyclins A, D2 and D3 in individual normal mitogen stimulated lymphocytes and in MOLT-4 leukemic cells analyzed by multiparameter flow cytometry.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(5):893-9.
1994: Li X; Traganos F; Darzynkiewicz Z
Simultaneous analysis of DNA replication and apoptosis during treatment of HL-60 cells with camptothecin and hyperthermia and mitogen stimulation of human lymphocytes.
Cancer research 1994;54(16):4289-93.
1994: Gong J; Ardelt B; Traganos F; Darzynkiewicz Z
Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines.
Cancer research 1994;54(16):4285-8.
1994: Gong J; Traganos F; Darzynkiewicz Z
Staurosporine blocks cell progression through G1 between the cyclin D and cyclin E restriction points.
Cancer research 1994;54(12):3136-9.
1994: Gong J; Traganos F; Darzynkiewicz Z
A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry.
Analytical biochemistry 1994;218(2):314-9.
1994: Hotz M A; Gong J; Traganos F; Darzynkiewicz Z
Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes.
Cytometry 1994;15(3):237-44.
1994: Traganos F; Gong J; Ardelt B; Darzynkiewicz Z
Effect of staurosporine on MOLT-4 cell progression through G2 and on cytokinesis.
Journal of cellular physiology 1994;158(3):535-44.
1994: Li X; Gong J; Feldman E; Seiter K; Traganos F; Darzynkiewicz Z
Apoptotic cell death during treatment of leukemias.
Leukemia & lymphoma 1994;13 Suppl 1():65-70.
1994: Darzynkiewicz Z; Gong J; Traganos F
Analysis of DNA content and cyclin protein expression in studies of DNA ploidy, growth fraction, lymphocyte stimulation, and the cell cycle.
Methods in cell biology 1994;41():421-35.
1994: Traganos F; Darzynkiewicz Z
Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations.
Methods in cell biology 1994;41():185-94.
1993: Gong J; Traganos F; Darzynkiewicz Z
Simultaneous analysis of cell cycle kinetics at two different DNA ploidy levels based on DNA content and cyclin B measurements.
Cancer research 1993;53(21):5096-9.
1993: Traganos F; Kapuscinski J; Gong J; Ardelt B; Darzynkiewicz R J; Darzynkiewicz Z
Caffeine prevents apoptosis and cell cycle effects induced by camptothecin or topotecan in HL-60 cells.
Cancer research 1993;53(19):4613-8.
1993: Gorczyca W; Traganos F; Jesionowska H; Darzynkiewicz Z
Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells.
Experimental cell research 1993;207(1):202-5.
1993: Gorczyca W; Gong J; Ardelt B; Traganos F; Darzynkiewicz Z
The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents.
Cancer research 1993;53(13):3186-92.
1993: Darzynkiewicz Z; Gorczyca W; Lassota P; Traganos F
Altered sensitivity of DNA in situ to denaturation in apoptotic cells.
Annals of the New York Academy of Sciences 1993;677():334-40.
1992: Traganos F; Ardelt B; Halko N; Bruno S; Darzynkiewicz Z
Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells.
Cancer research 1992;52(22):6200-8.
1992: Hotz M A; Traganos F; Darzynkiewicz Z
Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation.
Experimental cell research 1992;201(1):184-91.
1992: Hotz M A; Del Bino G; Lassota P; Traganos F; Darzynkiewicz Z
Cytostatic and cytotoxic effects of fostriecin on human promyelocytic HL-60 and lymphocytic MOLT-4 leukemic cells.
Cancer research 1992;52(6):1530-5.
1992: Bruno S; Ardelt B; Skierski J S; Traganos F; Darzynkiewicz Z
Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes.
Cancer research 1992;52(2):470-3.
1992: Darzynkiewicz Z; Bruno S; Del Bino G; Gorczyca W; Hotz M A; Lassota P; Traganos F
Features of apoptotic cells measured by flow cytometry.
Cytometry 1992;13(8):795-808.
1991: Traganos F; Kapuscinski J; Darzynkiewicz Z
Caffeine modulates the effects of DNA-intercalating drugs in vitro: a flow cytometric and spectrophotometric analysis of caffeine interaction with novantrone, doxorubicin, ellipticine, and the doxorubicin analogue AD198.
Cancer research 1991;51(14):3682-9.
1991: Traganos F; Kaminska-Eddy B; Darzynkiewicz Z
Caffeine reverses the cytotoxic and cell kinetic effects of Novantrone (mitoxantrone).
Cell proliferation 1991;24(3):305-19.
1990: Traganos F; Kimmel M
The stathmokinetic experiment: a single-parameter and multiparameter flow cytometric analysis.
Methods in cell biology 1990;33():249-70.

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