FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Francesco Trapasso

Research Profile

Genes & Molecular Sequences

Genes, Tumor Suppressor

Chemicals & Drugs

Anatomy

Living Beings

Physiology

Disorders

Procedures

Genetic Therapy

Co-author Network

Publications

TOP 3
Eugenio Gaudio; Thomas J Kipps; Gregory B Lesinski; Chenglong Li; Francesca Lovat; Apollinaire Ngankeu; Francesco Paduano; Yong Peng; Laura Rassenti; Mohammed A Shuaib; Hui-Lung Sun; Francesco Trapasso; nicola zanesi; Rami I Aqeilan; Alexey Efanov; Muller Fabbri; Pierluigi Gasparini; Carlo M Croce
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.
Rodolfo Iuliano; francesco baudi; Vincenzo Dattilo; Francesco Trapasso; Marco Flavio Michele Vismara; Nicola Perrotti
The Role of MicroRNAs in Cancer Susceptibility.
Francesco Paduano; Camillo Palmieri; Nicola Perrotti; Francesco Trapasso; Valter Agosti; Anna Bilotta; Vincenzo Dattilo; Alfredo Fusco; Eugenio Gaudio; Miranda Menniti; Domenico Narciso; Rodolfo Iuliano
Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Francesco Trapasso (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Eugenio Gaudio; Thomas J Kipps; Gregory B Lesinski; Chenglong Li; Francesca Lovat; Apollinaire Ngankeu; Francesco Paduano; Yong Peng; Laura Rassenti; Mohammed A Shuaib; Hui-Lung Sun; Francesco Trapasso; nicola zanesi; Rami I Aqeilan; Alexey Efanov; Muller Fabbri; Pierluigi Gasparini; Carlo M Croce
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.
Blood 2013;121(2):351-9.
2013: Rodolfo Iuliano; francesco baudi; Vincenzo Dattilo; Francesco Trapasso; Marco Flavio Michele Vismara; Nicola Perrotti
The Role of MicroRNAs in Cancer Susceptibility.
BioMed research international 2013;2013():591931.
2013: Francesco Paduano; Camillo Palmieri; Nicola Perrotti; Francesco Trapasso; Valter Agosti; Anna Bilotta; Vincenzo Dattilo; Alfredo Fusco; Eugenio Gaudio; Miranda Menniti; Domenico Narciso; Rodolfo Iuliano
Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328.
The FEBS journal 2013;280(2):401-12.
2012: Francesco Paduano; Camillo Palmieri; Nicola Perrotti; Cinzia Raso; Marina Sala; Giuseppe Scala; Giuseppe Viglietto; Valter Agosti; Stefano Alcaro; Anna Artese; Anna Bilotta; Pietro Campiglia; Alfonso Carotenuto; Carlo M Croce; Giovanni Cuda; Alfredo Fusco; Marco Gaspari; Eugenio Gaudio; Isabel Gomez-Monterrey; Enrico Iaccino; Rodolfo Iuliano; Graziella Mangone; Domenico Narciso; Ettore Novellino; Francesco Ortuso; Francesco Trapasso
Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity.
ACS chemical biology 2012;7(10):1666-76.
2012: Cinzia Rinaldo; M Eugenia Schininà; Francesca Siepi; Francesco Trapasso; Armando Bartolazzi; Laura Ciuffini; Enrico Cundari; Donatella D'Eliseo; Alfredo Fusco; Alessandra Giorgi; Alessandra Gradi; Giulia Guarguaglini; Alice Moncada; Giovanna M Pierantoni; Andrea Prodosmo; Silvia Soddu
HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody.
Molecular cell 2012;47(1):87-98.
2012: Stefania Nucara; Nicola Perrotti; Benedetto Caroleo; Vincenzo Guadagnino; Francesco Trapasso
Natural history and clinical response: "it's the virus, stupid, or is it the host?".
BMC infectious diseases 2012;12 Suppl 2():S6.
2011: Antonella Peduto; Carmen Petronzi; Francesco Trapasso; Antonella Virgilio; Filomena Fiorito; Salvatore Florio; Aldo Galeone; Concetta Giancola; Antonio Massa; Francesco Paduano; Bruno Pagano; Veronica Esposito; Rosanna Filosa
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands.
Bioorganic & medicinal chemistry 2011;19(21):6419-29.
2011: Stefania Nucara; Emma Colao; Graziella Mangone; francesco baudi; Fernanda Fabiani; Donatella Nocera; Giuseppe Passafaro; Teresa Longo; Anna Elisa Laria; Paola Malatesta; Rosario Amato; Francesco Trapasso; Nicola Perrotti
Identification of a new mutation in the gene coding for hairless protein responsible for alopecia universalis: The importance of direct gene sequencing.
Dermatology online journal 2011;17(1):3.
2010: Rodolfo Iuliano; Dario Palmieri; Huiling He; Angela Iervolino; Eleonora Borbone; pierlorenzo pallante; Alessandra Cianflone; Rebecca Nagy; Hansjuerg Alder; George A Calin; Francesco Trapasso; Carla Giordano; Carlo M Croce; ALBERT DE LA CHAPELLE; Alfredo Fusco
Role of PTPRJ genotype in papillary thyroid carcinoma risk.
Endocrine-related cancer 2010;17(4):1001-6.
2009: Ugo Bottoni; Francesco Trapasso
The role of G-CSF in the treatment of advanced tumors.
Cancer biology & therapy 2009;8(18):1744-6.
2009: Francesco Trapasso; Rami I Aqeilan; Rodolfo Iuliano; Rosa Visone; Eugenio Gaudio; Laura Ciuffini; Hansjuerg Alder; francesco paduano; Giovanna Maria Pierantoni; Silvia Soddu; Carlo M Croce; Alfredo Fusco
Targeted disruption of the murine homeodomain-interacting protein kinase-2 causes growth deficiency in vivo and cell cycle arrest in vitro.
DNA and cell biology 2009;28(4):161-7.
2009: Rodolfo Iuliano; Cinzia Raso; Alfina Quintiero; Ilaria Le Pera; Flavia Pichiorri; Tiziana Palumbo; Dario Palmieri; Alessandra Pattarozzi; Tullio Florio; Giuseppe Viglietto; Francesco Trapasso; Carlo Maria Croce; Alfredo Fusco
The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes and cell localization.
Journal of biochemistry 2009;145(3):377-85.
2008: Barbara Quaresima; Francesco Romeo; Maria C Faniello; Maddalena Di Sanzo; Chang-gong liu; Annamaria Lavecchia; Cristian Taccioli; Eugenio Gaudio; francesco baudi; Francesco Trapasso; Carlo M Croce; Giovanni Cuda; Francesco Costanzo
BRCA1 5083del19 mutant allele selectively up-regulates periostin expression in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(21):6797-803.
2008: Flavia Pichiorri; Hideshi Ishii; Hiroshi Okumura; Francesco Trapasso; Ya Wang; Kay Huebner
Molecular parameters of genome instability: roles of fragile genes at common fragile sites.
Journal of cellular biochemistry 2008;104(5):1525-33.
2008: Sai Yendamuri; Francesco Trapasso; George A Calin
ARLTS1 - a novel tumor suppressor gene.
Cancer letters 2008;264(1):11-20.
2008: Francesco Trapasso; Flavia Pichiorri; Marco Gaspari; Tiziana Palumbo; Rami I Aqeilan; Eugenio Gaudio; Hiroshi Okumura; Rodolfo Iuliano; Giampiero Di Leva; Muller Fabbri; David E Birk; Cinzia Raso; Kari Green-Church; Luigi G Spagnoli; Salvatore Venuta; Kay Huebner; Carlo M Croce
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
The Journal of biological chemistry 2008;283(20):13736-44.
2007: Sai Yendamuri; Francesco Trapasso; Manuela Ferracin; Rossano Cesari; Cinzia Sevignani; Masayoshi Shimizu; Shashi Rattan; Tamotsu Kuroki; Kristoffel R Dumon; Florencia Bullrich; Chang-gong liu; Massimo Negrini; Noel N Williams; Larry R Kaiser; Carlo M Croce; George A Calin
Tumor suppressor functions of ARLTS1 in lung cancers.
Cancer research 2007;67(16):7738-45.
2007: Rami I Aqeilan; Francesco Trapasso; Sadiq Hussain; Stefan Costinean; Dean Marshall; yuri pekarsky; John Patrick Hagan; nicola zanesi; Mohamed Kaou; Gary S Stein; Jane B Lian; Carlo M Croce
Targeted deletion of Wwox reveals a tumor suppressor function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):3949-54.
2006: Eugenio Gaudio; Alexey Palamarchuk; Tiziana Palumbo; Francesco Trapasso; yuri pekarsky; Carlo M Croce; Rami I Aqeilan
Physical association with WWOX suppresses c-Jun transcriptional activity.
Cancer research 2006;66(24):11585-9.
2006: Hideshi Ishii; Koshi Mimori; Hiroshi Inoue; Taeko Inageta; Kazuhiro Ishikawa; Shuho Semba; Teresa Druck; Francesco Trapasso; Kenzaburo Tani; Andrea Vecchione; Carlo M Croce; Masaki Mori; Kay Huebner
Fhit modulates the DNA damage checkpoint response.
Cancer research 2006;66(23):11287-92.
2006: Fabio Petrocca; Dimitrios Iliopoulos; Haiyan R Qin; Milena S Nicoloso; Sai Yendamuri; Sylwia E Wojcik; Masayoshi Shimizu; Gianpiero Di Leva; Aldo Vecchione; Francesco Trapasso; Andrew K Godwin; Massimo Negrini; George A Calin; Carlo M Croce
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
Cancer research 2006;66(21):10287-91.
2006: Shuho Semba; Shuang-Yin Han; Haiyan R Qin; Kelly A McCorkell; Dimitrios Iliopoulos; yuri pekarsky; Teresa Druck; Francesco Trapasso; Carlo M Croce; Kay Huebner
Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor.
The Journal of biological chemistry 2006;281(38):28244-53.
2006: Angela Iervolino; Rodolfo Iuliano; Francesco Trapasso; Giuseppe Viglietto; Rosa Marina Melillo; Francesca Carlomagno; Massimo Santoro; Alfredo Fusco
The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins.
Cancer research 2006;66(12):6280-7.
2006: Francesco Trapasso; Alessandra Drusco; Stefan Costinean; Hansjuerg Alder; Rami I Aqeilan; Rodolfo Iuliano; Eugenio Gaudio; Cinzia Raso; nicola zanesi; Carlo M Croce; Alfredo Fusco
Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis.
DNA and cell biology 2006;25(6):376-82.
2006: Flavia Pichiorri; Francesco Trapasso; Tiziana Palumbo; Rami I Aqeilan; Alessandra Drusco; Bradley W Blaser; Dimitrios Iliopoulos; Michael A Caligiuri; Kay Huebner; Carlo M Croce
Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3494-501.
2006: Shuho Semba; Francesco Trapasso; Muller Fabbri; Kelly A McCorkell; Stefano Volinia; Teresa Druck; Dimitrios Iliopoulos; yuri pekarsky; H Ishii; Preston N Garrison; Larry D Barnes; Carlo M Croce; Kay Huebner
Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.
Oncogene 2006;25(20):2860-72.
2005: Muller Fabbri; Dimitrios Iliopoulos; Francesco Trapasso; Rami I Aqeilan; Amelia Cimmino; nicola zanesi; Sai Yendamuri; Shuang-Yin Han; Dino Amadori; Kay Huebner; Carlo M Croce
WWOX gene restoration prevents lung cancer growth in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15611-6.
2005: Alessandra Drusco; nicola zanesi; Claudia Roldo; Francesco Trapasso; John L Farber; Louise Y Y Fong; Carlo M Croce
Knockout mice reveal a tumor suppressor function for Testin.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10947-51.
2005: Rami I Aqeilan; Valentina Donati; Alexey Palamarchuk; Francesco Trapasso; Mohamed Kaou; yuri pekarsky; Marius Sudol; Carlo M Croce
WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function.
Cancer research 2005;65(15):6764-72.
2005: Ilaria Le Pera; Rodolfo Iuliano; Tullio Florio; Christiane Susini; Francesco Trapasso; Massimo Santoro; Lorenzo Chiariotti; Gennaro Schettini; Giuseppe Viglietto; Alfredo Fusco
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.
Oncogene 2005;24(19):3187-95.
2004: Rodolfo Iuliano; Ilaria Le Pera; Carmela Cristofaro; Francesco Baudi; Franco Arturi; pierlorenzo pallante; Maria Luisa Martelli; Francesco Trapasso; Lorenzo Chiariotti; Alfredo Fusco
The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis.
Oncogene 2004;23(52):8432-8.
2004: Francesco Trapasso; Sai Yendamuri; Kristoffel R Dumon; Rodolfo Iuliano; Rossano Cesari; Byron Feig; Robin Seto; Luisa Infante; Hideshi Ishii; Aldo Vecchione; Matthew J During; Carlo M Croce; Alfredo Fusco
Restoration of receptor-type protein tyrosine phosphatase eta function inhibits human pancreatic carcinoma cell growth in vitro and in vivo.
Carcinogenesis 2004;25(11):2107-14.
2004: Francesco Trapasso; Manuela Sarti; Rossano Cesari; Sai Yendamuri; Kristoffel R Dumon; Rami I Aqeilan; Francesca Pentimalli; Luisa Infante; Hansjuerg Alder; Nobutsugu Abe; Takashi Watanabe; Giuseppe Viglietto; Carlo M Croce; Alfredo Fusco
Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models.
Cancer gene therapy 2004;11(9):633-41.
2004: Rami I Aqeilan; Tamotsu Kuroki; yuri pekarsky; Omar Albagha; Francesco Trapasso; Raffaele Baffa; Kay Huebner; Pamela Edmonds; Carlo M Croce
Loss of WWOX expression in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3053-8.
2004: Tamotsu Kuroki; Sai Yendamuri; Francesco Trapasso; Ayumi Matsuyama; Rami I Aqeilan; Hansjuerg Alder; Shashi Rattan; Rossano Cesari; Maria L Nolli; Noel N Williams; Masaki Mori; Takashi Kanematsu; Carlo M Croce
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2459-65.
2004: Rami I Aqeilan; yuri pekarsky; Juan J Herrero; Alexey Palamarchuk; Jean Letofsky; Teresa Druck; Francesco Trapasso; Shuang-Yin Han; Gerry Melino; Kay Huebner; Carlo M Croce
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4401-6.
2004: Hideshi Ishii; Andrea Vecchione; Louise Y Y Fong; nicola zanesi; Francesco Trapasso; Yusuke Furukawa; Raffaele Baffa; Kay Huebner; Carlo M Croce
Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses.
Current gene therapy 2004;4(1):53-63.
2003: Ayumi Matsuyama; Takeshi Shiraishi; Francesco Trapasso; Tamotsu Kuroki; Hansjuerg Alder; Masaki Mori; Kay Huebner; Carlo M Croce
Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14988-93.
2003: Hideshi Ishii; Andrea Vecchione; Yutaka Furukawa; Krittaya Sutheesophon; Shuang-Yin Han; Teresa Druck; Tamotsu Kuroki; Francesco Trapasso; Miki Nishimura; Yasushi Saito; Keiya Ozawa; Carlo M Croce; Kay Huebner; Yusuke Furukawa
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
Molecular cancer research : MCR 2003;1(13):940-7.
2003: Hideshi Ishii; nicola zanesi; Aldo Vecchione; Francesco Trapasso; Sai Yendamuri; Manuela Sarti; Raffaele Baffa; Matthew J During; Kay Huebner; Louise Y Y Fong; Carlo M Croce
Regression of upper gastric cancer in mice by FHIT gene delivery.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1768-70.
2003: Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Masaki Mori; Carlo M Croce
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
Cancer research 2003;63(13):3724-8.
2003: Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Noel N Williams; Larry R Kaiser; Carlo M Croce
Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer.
Cancer research 2003;63(12):3352-5.
2003: Rossano Cesari; Eric S Martin; George A Calin; Francesca Pentimalli; Roberta Bichi; Holly McAdams; Francesco Trapasso; Alessandra Drusco; Masayoshi Shimizu; Valeria Masciullo; Giuseppina D'Andrilli; Giovanni Scambia; Maria Cristina Picchio; Hansjuerg Alder; Andrew K Godwin; Carlo M Croce
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5956-61.
2003: Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Masaki Mori; Carlo M Croce
Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(4):1441-5.
2003: Gustavo Baldassarre; Sabrina Battista; Barbara Belletti; Sanjay Thakur; Francesca Pentimalli; Francesco Trapasso; Monica Fedele; Giovanna Maria Pierantoni; Carlo M Croce; Alfredo Fusco
Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma.
Molecular and cellular biology 2003;23(7):2225-38.
2003: Cinzia Sevignani; George A Calin; Rossano Cesari; Manuela Sarti; Hideshi Ishii; Sai Yendamuri; Aldo Vecchione; Francesco Trapasso; Carlo M Croce
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines.
Cancer research 2003;63(6):1183-7.
2003: Roberta Visconti; Filippo Schepis; Rodolfo Iuliano; Giovanna Maria Pierantoni; Li Zhang; Francesca Carlomagno; Caterina Battaglia; Maria Luisa Martelli; Francesco Trapasso; Massimo Santoro; Alfredo Fusco
Cloning and molecular characterization of a novel gene strongly induced by the adenovirus E1A gene in rat thyroid cells.
Oncogene 2003;22(7):1087-97.
2003: Francesco Trapasso; Agnieszka Krakowiak; Rossano Cesari; Jeffrey Arkles; Sai Yendamuri; Hideshi Ishii; Aldo Vecchione; Tamotsu Kuroki; Pawel Bieganowski; Helen C Pace; Kay Huebner; Carlo M Croce; Charles Brenner
Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1592-7.
2003: Rodolfo Iuliano; Francesco Trapasso; Ilaria Le Pera; Filippo Schepis; Irene Samà; Alessandra Clodomiro; Kristoffel R Dumon; Massimo Santoro; Lorenzo Chiariotti; Giuseppe Viglietto; Alfredo Fusco
An adenovirus carrying the rat protein tyrosine phosphatase eta suppresses the growth of human thyroid carcinoma cell lines in vitro and in vivo.
Cancer research 2003;63(4):882-6.
2003: Sai Yendamuri; Tamotsu Kuroki; Francesco Trapasso; Adam C Henry; Kristoffel R Dumon; Kay Huebner; Noel N Williams; Larry R Kaiser; Carlo M Croce
WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer.
Cancer research 2003;63(4):878-81.
2002: Giovanni Santelli; Paola Cannada Bartoli; Ada Giuliano; Antonio Porcellini; Alba Mineo; Maria Vittoria Barone; Immacolata Busiello; Francesco Trapasso; Daniela Califano; Alfredo Fusco
Thymosin beta-10 protein synthesis suppression reduces the growth of human thyroid carcinoma cells in semisolid medium.
Thyroid : official journal of the American Thyroid Association 2002;12(9):765-72.
2002: Tamotsu Kuroki; Francesco Trapasso; Takeshi Shiraishi; Hansjuerg Alder; Koshi Mimori; Masaki Mori; Carlo M Croce
Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma.
Cancer research 2002;62(8):2258-60.
2002: Aldo Vecchione; Hideshi Ishii; Gustavo Baldassarre; Pierfrancesco Bassi; Francesco Trapasso; Hansjuerg Alder; Francesco Pagano; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
FEZ1/LZTS1 is down-regulated in high-grade bladder cancer, and its restoration suppresses tumorigenicity in transitional cell carcinoma cells.
The American journal of pathology 2002;160(4):1345-52.
2001: Tullio Florio; Sara Arena; Stefano Thellung; Rodolfo Iuliano; Alessandro Corsaro; Alessandro Massa; Alessandra Pattarozzi; Adriana Bajetto; Francesco Trapasso; Alfredo Fusco; Gennaro Schettini
The activation of the phosphotyrosine phosphatase eta (r-PTP eta) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation.
Molecular endocrinology (Baltimore, Md.) 2001;15(10):1838-52.
2001: Hideshi Ishii; Aldo Vecchione; Yoshiki Murakumo; Gustavo Baldassarre; Shin-ichiro Numata; Francesco Trapasso; Hansjuerg Alder; Raffaele Baffa; Carlo M Croce
FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10374-9.
2001: Rodolfo Iuliano; Francesco Trapasso; I Samà; Ilaria Le Pera; Maria Luisa Martelli; Francesca Lembo; Massimo Santoro; Giuseppe Viglietto; Lorenzo Chiariotti; Alfredo Fusco
Rat protein tyrosine phosphatase eta physically interacts with the PDZ domains of syntenin.
FEBS letters 2001;500(1-2):41-4.
2001: Kristoffel R Dumon; Hideshi Ishii; Aldo Vecchione; Francesco Trapasso; Gustavo Baldassarre; F Chakrani; Teresa Druck; E F Rosato; Noel N Williams; Raffaele Baffa; Matthew J During; Kay Huebner; Carlo M Croce
Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer.
Cancer research 2001;61(12):4827-36.
2001: Aldo Vecchione; Hideshi Ishii; Yih-Horng Shiao; Francesco Trapasso; M Rugge; J F Tamburrino; Yoshiki Murakumo; Hansjuerg Alder; Carlo M Croce; Raffaele Baffa
Fez1/lzts1 alterations in gastric carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(6):1546-52.
2001: Kristoffel R Dumon; Hideshi Ishii; Louise Y Y Fong; nicola zanesi; Vincenzo Fidanza; Rita Mancini; Aldo Vecchione; Raffaele Baffa; Francesco Trapasso; Matthew J During; Kay Huebner; Carlo M Croce
FHIT gene therapy prevents tumor development in Fhit-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3346-51.
2001: Hideshi Ishii; Kristoffel R Dumon; Aldo Vecchione; Francesco Trapasso; Koshi Mimori; Hansjuerg Alder; Masaki Mori; Gabriella Sozzi; Raffaele Baffa; Kay Huebner; Carlo M Croce
Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells.
Cancer research 2001;61(4):1578-84.
2000: Francesco Trapasso; Rodolfo Iuliano; Angelo Boccia; A Stella; Roberta Visconti; Paola Bruni; Gustavo Baldassarre; Massimo Santoro; Giuseppe Viglietto; Alfredo Fusco
Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).
Molecular and cellular biology 2000;20(24):9236-46.
2000: Rodolfo Iuliano; Francesco Trapasso; A Stella; Ilaria Le Pera; R M Melillo; Paola Bruni; Gustavo Baldassarre; Lorenzo Chiariotti; Massimo Santoro; Giuseppe Viglietto; Alfredo Fusco
Pivotal role of the RB family proteins in in vitro thyroid cell transformation.
Experimental cell research 2000;260(2):257-67.
2000: Maria Luisa Martelli; Maria Giuseppina Miano; C Battaglia; Francesco Trapasso; A Stella; Rodolfo Iuliano; Roberta Visconti; James A Fagin; Massimo Santoro; Alfredo Fusco
The highly malignant phenotype of anaplastic thyroid carcinoma cell lines is recessive.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(4):515-21.
2000: Paola Bruni; Angelo Boccia; Gustavo Baldassarre; Francesco Trapasso; Massimo Santoro; Gennaro Chiappetta; Alfredo Fusco; Giuseppe Viglietto
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1.
Oncogene 2000;19(28):3146-55.
1999: Gustavo Baldassarre; Barbara Belletti; Paola Bruni; Angelo Boccia; Francesco Trapasso; Francesca Pentimalli; Maria Vittoria Barone; Gennaro Chiappetta; MT Vento; S Spiezia; Alfredo Fusco; Giuseppe Viglietto
Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells.
The Journal of clinical investigation 1999;104(7):865-74.
1999: Giovanni Santelli; Daniela Califano; Gennaro Chiappetta; MT Vento; Paola Cannada Bartoli; F Zullo; Francesco Trapasso; Giuseppe Viglietto; Alfredo Fusco
Thymosin beta-10 gene overexpression is a general event in human carcinogenesis.
The American journal of pathology 1999;155(3):799-804.
1999: Giovanni Monteleone; Francesco Trapasso; T Parrello; Livia Biancone; A Stella; Rodolfo Iuliano; Francesco Luzza; A Fusco; Francesco Pallone
Bioactive IL-18 expression is up-regulated in Crohn's disease.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):143-7.
1999: Francesco Trapasso; Rodolfo Iuliano; Eusebio Chiefari; Franco Arturi; A Stella; Sebastiano Filetti; Alfredo Fusco; Diego Russo
Iodide symporter gene expression in normal and transformed rat thyroid cells.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(5):447-51.
1998: Maria Luisa Martelli; Francesco Trapasso; Paola Bruni; Maria Teresa Berlingieri; C Battaglia; MT Vento; Barbara Belletti; Rodolfo Iuliano; Massimo Santoro; Giuseppe Viglietto; Alfredo Fusco
Protein tyrosine phosphatase-eta expression is upregulated by the PKA-dependent and is downregulated by the PKC-dependent pathways in thyroid cells.
Experimental cell research 1998;245(1):195-202.
1998: Daniela Califano; Carmen Monaco; Giovanni Santelli; Ada Giuliano; Maria L Veronese; Maria Teresa Berlingieri; Vittorio de Franciscis; N Berger; Francesco Trapasso; Massimo Santoro; Giuseppe Viglietto; Alfredo Fusco
Thymosin beta-10 gene overexpression correlated with the highly malignant neoplastic phenotype of transformed thyroid cells in vivo and in vitro.
Cancer research 1998;58(4):823-8.
1997: Roberta Visconti; J Cerutti; Sabrina Battista; Monica Fedele; Francesco Trapasso; K Zeki; M P Miano; F de Nigris; Laura Casalino; F Curcio; Massimo Santoro; Alfredo Fusco
Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFkappaB p65 protein expression.
Oncogene 1997;15(16):1987-94.
1997: L Zhang; Maria Luisa Martelli; C Battaglia; Francesco Trapasso; Donatella Tramontano; Giuseppe Viglietto; Antonio Porcellini; Massimo Santoro; Alfredo Fusco
Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase.
Experimental cell research 1997;235(1):62-70.
1996: Gennaro Chiappetta; V Avantaggiato; Roberta Visconti; Monica Fedele; Sabrina Battista; Francesco Trapasso; B M Merciai; V Fidanza; Vincenzo Giancotti; Massimo Santoro; A Simeone; A Fusco
High level expression of the HMGI (Y) gene during embryonic development.
Oncogene 1996;13(11):2439-46.
1996: Francesco Trapasso; Maria Luisa Martelli; C Battaglia; E Angotti; E Mele; A Stella; J Samarut; Vittorio E Avvedimento; A Fusco
The v-erbA oncogene selectively inhibits iodide uptake in rat thyroid cells.
Oncogene 1996;12(9):1879-88.
1996: J Cerutti; Francesco Trapasso; C Battaglia; L Zhang; Maria Luisa Martelli; Roberta Visconti; Maria Teresa Berlingieri; James A Fagin; Massimo Santoro; A Fusco
Block of c-myc expression by antisense oligonucleotides inhibits proliferation of human thyroid carcinoma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(1):119-26.
1995: Sabrina Battista; Maria Luisa Martelli; Monica Fedele; Gennaro Chiappetta; Francesco Trapasso; Gabriella De Vita; C Battaglia; Massimo Santoro; Giuseppe Viglietto; James A Fagin
A mutated p53 gene alters thyroid cell differentiation.
Oncogene 1995;11(10):2029-37.
1995: Giuseppe Viglietto; Domenico Maglione; M Rambaldi; J Cerutti; A Romano; Francesco Trapasso; Monica Fedele; P Ippolito; Gennaro Chiappetta; Gerardo Botti
Upregulation of vascular endothelial growth factor (VEGF) and downregulation of placenta growth factor (PlGF) associated with malignancy in human thyroid tumors and cell lines.
Oncogene 1995;11(8):1569-79.
1993: C Battaglia; Maria Teresa Berlingieri; Maria Luisa Martelli; Francesco Trapasso; P Delli Bovi; A Fusco
Mitogenic and dedifferentiating effect of the K-fgf/hst oncogene on rat thyroid PC clone 3 epithelial cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(3):185-92.