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Ioannis Bossis

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Krit Ritthipichai; Ioannis Bossis; Yuchen Nan; Yanjin Zhang
Viral FLICE inhibitory protein of rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation.
MANISH KUMAR; Xiuli Yang; John F Anderson; Ioannis Bossis; Toru Kariu; Simarjot Kaur; Utpal Pal
Borrelia burgdorferi BBA52 is a potential target for transmission blocking Lyme disease vaccine.
Yogendra Rajawat; Zoe Hilioti; Ioannis Bossis
Retinoic acid induces autophagosome maturation through redistribution of the cation-independent mannose-6-phosphate receptor.

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All Publications

2012: Krit Ritthipichai; Ioannis Bossis; Yuchen Nan; Yanjin Zhang
Viral FLICE inhibitory protein of rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation.
PloS one 2012;7(6):e39438.
2011: MANISH KUMAR; Xiuli Yang; John F Anderson; Ioannis Bossis; Toru Kariu; Simarjot Kaur; Utpal Pal
Borrelia burgdorferi BBA52 is a potential target for transmission blocking Lyme disease vaccine.
Vaccine 2011;29(48):9012-9.
2011: Yogendra Rajawat; Zoe Hilioti; Ioannis Bossis
Retinoic acid induces autophagosome maturation through redistribution of the cation-independent mannose-6-phosphate receptor.
Antioxidants & redox signaling 2011;14(11):2165-77.
2010: Yogendra Rajawat; Zoe Hilioti; Ioannis Bossis
Autophagy: a target for retinoic acids.
Autophagy 2010;6(8):1224-6.
2010: Sharmila Pejawar-Gaddy; Yogendra Rajawat; Zoe Hilioti; Jia Xue; Daniel F Gaddy; Olivera J Finn; Raphael P Viscidi; Ioannis Bossis
Generation of a tumor vaccine candidate based on conjugation of a MUC1 peptide to polyionic papillomavirus virus-like particles.
Cancer immunology, immunotherapy : CII 2010;59(11):1685-96.
2010: Emily G Severance; Faith B Dickerson; Meredith Halling; Bogdana Krivogorsky; Luladey Haile; Shuojia Yang; Cassie Stallings; Andrea E Origoni; Ioannis Bossis; Jianchun Xiao; Didier Dupont; Willem Haasnoot; Robert H Yolken
Subunit and whole molecule specificity of the anti-bovine casein immune response in recent onset psychosis and schizophrenia.
Schizophrenia research 2010;118(1-3):240-7.
2010: Madson Q Almeida; michael muchow; Sosipatros Boikos; Andrew J Bauer; Kurt J Griffin; Kit Man Tsang; Chris Cheadle; Tonya Watkins; Feng Wen; Matthew F Starost; Ioannis Bossis; Maria Nesterova; Constantine A Stratakis
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling.
Human molecular genetics 2010;19(8):1387-98.
2009: Audrey Robinson-White; Ioannis Bossis; Hui-Pin Hsiao; Maria Nesterova; Wolfgang W Leitner; Constantine Straturis
8-Cl-adenosine inhibits proliferation and causes apoptosis in B-lymphocytes via protein kinase A-dependent and independent effects: implications for treatment of Carney complex-associated tumors.
The Journal of clinical endocrinology and metabolism 2009;94(10):4061-9.
2009: Yogendra S Rajawat; Zoe Hilioti; Ioannis Bossis
Aging: central role for autophagy and the lysosomal degradative system.
Ageing research reviews 2009;8(3):199-213.
2009: Harilakshmi Kannan; Sumin Fan; Deendayal Patel; Ioannis Bossis; Yanjin Zhang
The hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics.
Journal of virology 2009;83(13):6375-82.
2008: Emily G Severance; Ioannis Bossis; Faith B Dickerson; Cassie R Stallings; Andrea E Origoni; Anne Sullens; Robert H Yolken; Raphael P Viscidi
Development of a nucleocapsid-based human coronavirus immunoassay and estimates of individuals exposed to coronavirus in a U.S. metropolitan population.
Clinical and vaccine immunology : CVI 2008;15(12):1805-10.
2008: S L Heyerdahl; Sosipatros Boikos; Anelia D Horvath; Christoforos Giatzakis; Ioannis Bossis; Constantine Straturis
Protein kinase A subunit expression is altered in Bloom syndrome fibroblasts and the BLM protein is increased in adrenocortical hyperplasias: inverse findings for BLM and PRKAR1A.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(6):391-7.
2008: Sosipatros Boikos; Anelia D Horvath; S Heyerdahl; E Stein; Audrey Robinson-White; Ioannis Bossis; Jérôme Bertherat; J Aidan Carney; Constantine Straturis
Phosphodiesterase 11A expression in the adrenal cortex, primary pigmented nodular adrenocortical disease, and other corticotropin-independent lesions.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(5):347-53.
2008: Elise Meoli; Ioannis Bossis; Laure Cazabat; Manos Mavrakis; Anelia Horvath; Sotirios Stergiopoulos; Miriam L Shiferaw; Glawdys Fumey; Karine Perlemoine; michael muchow; Audrey Robinson-White; Frank D Weinberg; Maria Nesterova; Yianna Patronas; Lionel Groussin; Jérôme Bertherat; Constantine Straturis
Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors.
Cancer research 2008;68(9):3133-41.
2008: Elizabeth L Greene; Anelia D Horvath; Maria Nesterova; Christoforos Giatzakis; Ioannis Bossis; Constantine Straturis
In vitro functional studies of naturally occurring pathogenic PRKAR1A mutations that are not subject to nonsense mRNA decay.
Human mutation 2008;29(5):633-9.
2008: Maria Nesterova; Ioannis Bossis; Feng Wen; Anelia Horvath; Ludmila Matyakhina; Constantine Straturis
An immortalized human cell line bearing a PRKAR1A-inactivating mutation: effects of overexpression of the wild-type Allele and other protein kinase A subunits.
The Journal of clinical endocrinology and metabolism 2008;93(2):565-71.
2008: Anelia Horvath; Ioannis Bossis; Christoforos Giatzakis; Elizabeth Levine; Frank D Weinberg; Elise Meoli; Audrey Robinson-White; Jennifer Siegel; Payal Soni; Lionel Groussin; Ludmila Matyakhina; Somya Verma; Elaine Remmers; Maria Nesterova; J Aidan Carney; Jérôme Bertherat; Constantine Straturis
Large deletions of the PRKAR1A gene in Carney complex.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):388-95.
2008: Yogendra S Rajawat; Ioannis Bossis
Autophagy in aging and in neurodegenerative disorders.
Hormones (Athens, Greece) 2008;7(1):46-61.
2007: Ratish Gambhira; Balasubramanyam Karanam; Subhashini Jagu; Jeffrey N Roberts; Christopher B Buck; Ioannis Bossis; Hannah Alphs; Timothy D Culp; Neil Christensen; Richard B S Roden
A protective and broadly cross-neutralizing epitope of human papillomavirus L2.
Journal of virology 2007;81(24):13927-31.
2007: Tom E Porter; Sarvin Ghavam; michael muchow; Ioannis Bossis; Laura E Ellestad
Cloning of partial cDNAs for the chicken glucocorticoid and mineralocorticoid receptors and characterization of mRNA levels in the anterior pituitary gland during chick embryonic development.
Domestic animal endocrinology 2007;33(2):226-39.
2007: Manos Mavrakis; Jennifer Lippincott-Schwartz; Constantine Straturis; Ioannis Bossis
mTOR kinase and the regulatory subunit of protein kinase A (PRKAR1A) spatially and functionally interact during autophagosome maturation.
Autophagy 2007;3(2):151-3.
2006: Anelia Horvath; Christoforos Giatzakis; Audrey Robinson-White; Sosipatros Boikos; Elizabeth Levine; Kurt Griffin; Erica Stein; Virginia Kamvissi; Payal Soni; Ioannis Bossis; Wouter W de Herder; J Aidan Carney; Jérôme Bertherat; Peter K Gregersen; Elaine F Remmers; Constantine Straturis
Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population.
Cancer research 2006;66(24):11571-5.
2006: Ratish Gambhira; Patti Gravitt; Ioannis Bossis; Peter L Stern; Raphael P Viscidi; Richard B S Roden
Vaccination of healthy volunteers with human papillomavirus type 16 L2E7E6 fusion protein induces serum antibody that neutralizes across papillomavirus species.
Cancer research 2006;66(23):11120-4.
2006: Audrey Robinson-White; Wolfgang W Leitner; Eiman Aleem; Philipp Kaldis; Ioannis Bossis; Constantine Straturis
PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes.
Cancer research 2006;66(21):10603-12.
2006: Manos Mavrakis; Jennifer Lippincott-Schwartz; Constantine Straturis; Ioannis Bossis
Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency.
Human molecular genetics 2006;15(19):2962-71.
2006: Anelia Horvath; Sosipatros Boikos; Christoforos Giatzakis; Audrey Robinson-White; Lionel Groussin; Kurt J Griffin; Erica Stein; Elizabeth Levine; Georgia Delimpasi; Hui Pin Hsiao; Margaret F Keil; Sarah Heyerdahl; Ludmila Matyakhina; Rossella Libè; Amato Fratticci; Lawrence S Kirschner; Kevin Cramer; Rolf C Gaillard; Xavier Bertagna; J Aidan Carney; Jérôme Bertherat; Ioannis Bossis; Constantine Straturis
A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia.
Nature genetics 2006;38(7):794-800.
2006: Audrey Robinson-White; Elise Meoli; Sotirios Stergiopoulos; Anelia Horvath; Sosipatros Boikos; Ioannis Bossis; Constantine Straturis
PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex.
The Journal of clinical endocrinology and metabolism 2006;91(6):2380-8.
2006: Antonis Voutetakis; Amalia Sertedaki; SARANTIS LIVADAS; Paraskevi Xekouki; Ioannis Bossis; Catherine Dacou-Voutetakis; Maria Argyropoulou
Pituitary size fluctuation in long-term MR studies of PROP1 deficient patients: A persistent pathophysiological mechanism?
Journal of endocrinological investigation 2006;29(5):462-6.
2006: Tom E Porter; Laura E Ellestad; Allison Fay; Joanna L Stewart; Ioannis Bossis
Identification of the chicken growth hormone-releasing hormone receptor (GHRH-R) mRNA and gene: regulation of anterior pituitary GHRH-R mRNA levels by homologous and heterologous hormones.
Endocrinology 2006;147(5):2535-43.
2005: Antonis Voutetakis; Ioannis Bossis; Marc R Kok; Weitian Zhang; Jianghua Wang; Ana P Cotrim; Changyu Zheng; John A Chiorini; Lynnette K Nieman; Bruce J Baum
Salivary glands as a potential gene transfer target for gene therapeutics of some monogenetic endocrine disorders.
The Journal of endocrinology 2005;185(3):363-72.
2005: Giovanni Di Pasquale; Agnieszka Rzadzinska; Mark E Schneider; Ioannis Bossis; John A Chiorini; Anne E White-Olson
A novel bovine virus efficiently transduces inner ear neuroepithelial cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(6):849-55.
2005: Ioannis Bossis; Richard B S Roden; Ratish Gambhira; Rongcun Yang; Mitsuo Tagaya; Peter M Howley; Patricio Ignacio Meneses
Interaction of tSNARE syntaxin 18 with the papillomavirus minor capsid protein mediates infection.
Journal of virology 2005;79(11):6723-31.
2005: Marc R Kok; Antonis Voutetakis; Seiichi Yamano; Jianghua Wang; Ana P Cotrim; Hisako Katano; Ioannis Bossis; John A Chiorini; Simon D Tran; Paul P Tak; Bruce J Baum
Immune responses following salivary gland administration of recombinant adeno-associated virus serotype 2 vectors.
The journal of gene medicine 2005;7(4):432-41.
2005: michael muchow; Ioannis Bossis; Tom E Porter
Ontogeny of pituitary thyrotrophs and regulation by endogenous thyroid hormone feedback in the chick embryo.
The Journal of endocrinology 2005;184(2):407-16.
2004: Ioannis Bossis; Constantine Straturis
Minireview: PRKAR1A: normal and abnormal functions.
Endocrinology 2004;145(12):5452-8.
2004: Antonis Voutetakis; Amalia Sertedaki; SARANTIS LIVADAS; Maria Maniati-Christidi; Ioannis Mademtzis; Ioannis Bossis; Catherine Dacou-Voutetakis; Ioannis E Messinis
Ovulation induction and successful pregnancy outcome in two patients with Prop1 gene mutations.
Fertility and sterility 2004;82(2):454-7.
2004: Ioannis Bossis; Antonis Voutetakis; Ludmila Matyakhina; Svetlana Pack; Mones Abu-Asab; Isabelle Bourdeau; Kurt J Griffin; Nickolas A Courcoutsakis; Sotirios Stergiopoulos; Dalia L Batista; Maria Tsokos; Constantine Straturis
A pleiomorphic GH pituitary adenoma from a Carney complex patient displays universal allelic loss at the protein kinase A regulatory subunit 1A (PRKARIA) locus.
Journal of medical genetics 2004;41(8):596-600.
2004: Ioannis Bossis; Shotaro Nishimura; michael muchow; Tom E Porter
Pituitary expression of type I and type II glucocorticoid receptors during chicken embryonic development and their involvement in growth hormone cell differentiation.
Endocrinology 2004;145(7):3523-31.
2004: Michael Schmidt; Hisako Katano; Ioannis Bossis; John A Chiorini
Cloning and characterization of a bovine adeno-associated virus.
Journal of virology 2004;78(12):6509-16.
2004: Ioannis Bossis; Antonis Voutetakis; Thalia Bei; Fabiano Sandrini; Kurt J Griffin; Constantine Straturis
Protein kinase A and its role in human neoplasia: the Carney complex paradigm.
Endocrine-related cancer 2004;11(2):265-80.
2004: Antonis Voutetakis; Maria Argyropoulou; Amalia Sertedaki; SARANTIS LIVADAS; Paraskevi Xekouki; Maria Maniati-Christidi; Ioannis Bossis; Nikolaos Thalassinos; Nicholas Patronas; Catherine Dacou-Voutetakis
Pituitary magnetic resonance imaging in 15 patients with Prop1 gene mutations: pituitary enlargement may originate from the intermediate lobe.
The Journal of clinical endocrinology and metabolism 2004;89(5):2200-6.
2004: Antonis Voutetakis; Marc R Kok; Changyu Zheng; Ioannis Bossis; Jianghua Wang; Ana P Cotrim; Natanya Marracino; Corinne M Goldsmith; John A Chiorini; Y Peng Loh; Lynnette K Nieman; Bruce J Baum
Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3053-8.
2004: Constantine Straturis; Ioannis Bossis
Genetics of the adrenal gland.
Reviews in endocrine & metabolic disorders 2004;5(1):53-68.
2004: Constantine Straturis; Ludmila Matyakhina; Nickolas Courkoutsakis; Nicholas Patronas; Antonis Voutetakis; Sotirios Stergiopoulos; Ioannis Bossis; J Aidan Carney
Pathology and molecular genetics of the pituitary gland in patients with the 'complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas' (Carney complex).
Frontiers of hormone research 2004;32():253-64.
2003: Ioannis Bossis; John A Chiorini
Cloning of an avian adeno-associated virus (AAAV) and generation of recombinant AAAV particles.
Journal of virology 2003;77(12):6799-810.
2003: Ioannis Bossis; Tom E Porter
Evaluation of glucocorticoid-induced growth hormone gene expression in chicken embryonic pituitary cells using a novel in situ mRNA quantitation method.
Molecular and cellular endocrinology 2003;201(1-2):13-23.
2001: Ioannis Bossis; Tom E Porter
Identification of the somatostatin receptor subtypes involved in regulation of growth hormone secretion in chickens.
Molecular and cellular endocrinology 2001;182(2):203-13.
2000: Ioannis Bossis; Tom E Porter
Ontogeny of corticosterone-inducible growth hormone-secreting cells during chick embryonic development.
Endocrinology 2000;141(7):2683-90.