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Paul Trayhurn

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D Gao; Paul Trayhurn; Chen Bing
1,25-Dihydroxyvitamin D3 inhibits the cytokine-induced secretion of MCP-1 and reduces monocyte recruitment by human preadipocytes.
Jonathan R S Arch; Paul Trayhurn
Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification.
Paul Trayhurn
Hypoxia and adipose tissue function and dysfunction in obesity.

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All Publications

2013: D Gao; Paul Trayhurn; Chen Bing
1,25-Dihydroxyvitamin D3 inhibits the cytokine-induced secretion of MCP-1 and reduces monocyte recruitment by human preadipocytes.
International journal of obesity (2005) 2013;37(3):357-65.
2013: Jonathan R S Arch; Paul Trayhurn
Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification.
Frontiers in physiology 2013;4():64.
2013: Paul Trayhurn
Hypoxia and adipose tissue function and dysfunction in obesity.
Physiological reviews 2013;93(1):1-21.
2013: Edward T Wargent; Mohamed S Zaibi; Paul Trayhurn; Jonathan R S Arch; Chen Bing; Michael A Cawthorne; Dan Gao; Jacqueline F O'Dowd; Claire J Stocker
Contrasts between the effects of zinc-α2-glycoprotein, a putative β3/2-adrenoceptor agonist and the β3/2-adrenoceptor agonist BRL35135 in C57Bl/6 (ob/ob) mice.
The Journal of endocrinology 2013;216(2):157-68.
2012: Cherlyn Ding; Dan Gao; Paul Trayhurn; John Wilding; Chen Bing
Vitamin D signalling in adipose tissue.
The British journal of nutrition 2012;108(11):1915-23.
2012: Dawn Mazzatti; Adrian O'Hara; Fei-Ling Lim; I Stuart Wood; Paul Trayhurn
A microarray analysis of the hypoxia-induced modulation of gene expression in human adipocytes.
Archives of physiology and biochemistry 2012;118(3):112-20.
2011: Kieron Rooney; Paul Trayhurn
Lactate and the GPR81 receptor in metabolic regulation: implications for adipose tissue function and fatty acid utilisation by muscle during exercise.
The British journal of nutrition 2011;106(9):1310-6.
2011: V H Ryan; Paul Trayhurn; L Hunter; Penelope Morris; Alexander James German
11-Hydroxy-β-steroid dehydrogenase gene expression in canine adipose tissue and adipocytes: stimulation by lipopolysaccharide and tumor necrosis factor α.
Domestic animal endocrinology 2011;41(3):150-61.
2011: I Stuart Wood; Tanya Stezhka; Paul Trayhurn
Modulation of adipokine production, glucose uptake and lactate release in human adipocytes by small changes in oxygen tension.
Pflügers Archiv : European journal of physiology 2011;462(3):469-77.
2011: Kristin Eckardt; Annette Schober; Birgit Platzbecker; Tomas Mracek; Chen Bing; Paul Trayhurn; Jürgen Eckel
The adipokine zinc-α2-glycoprotein activates AMP kinase in human primary skeletal muscle cells.
Archives of physiology and biochemistry 2011;117(2):88-93.
2011: Daniella T Otway; Simone Mäntele; Silvia Bretschneider; John Wright; Paul Trayhurn; Debra Jean Skene; M Denise Robertson; Jonathan D Johnston
Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic.
Diabetes 2011;60(5):1577-81.
2011: Paul Trayhurn; Christian Andre Drevon; Jürgen Eckel
Secreted proteins from adipose tissue and skeletal muscle - adipokines, myokines and adipose/muscle cross-talk.
Archives of physiology and biochemistry 2011;117(2):47-56.
2011: T Mracek; N A Stephens; D Gao; Y Bao; J A Ross; M Rydén; P Arner; Paul Trayhurn; K C H Fearon; Chen Bing
Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients.
British journal of cancer 2011;104(3):441-7.
2011: Pedro González-Muniesa; Fátima Pérez de Heredia; Mary P Thompson; Cristiane de Oliveira; Paul Trayhurn
Fatty acids and hypoxia stimulate the expression and secretion of the adipokine ANGPTL4 (angiopoietin-like protein 4/ fasting-induced adipose factor) by human adipocytes.
Journal of nutrigenetics and nutrigenomics 2011;4(3):146-53.
2010: Chen Bing; T Mracek; D Gao; Paul Trayhurn
Zinc-α2-glycoprotein: an adipokine modulator of body fat mass?
International journal of obesity (2005) 2010;34(11):1559-65.
2010: P González-Muniesa; Chen Bing; Paul Trayhurn
Upregulation of the expression of inflammatory and angiogenic markers in human adipocytes by a synthetic cannabinoid, JTE-907.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2010;42(10):710-7.
2010: D Gao; Paul Trayhurn; Chen Bing
Macrophage-secreted factors inhibit ZAG expression and secretion by human adipocytes.
Molecular and cellular endocrinology 2010;325(1-2):135-42.
2010: Vivien H Ryan; Alexander James German; I Stuart Wood; Leif Hunter; Penelope Morris; Paul Trayhurn
Adipokine expression and secretion by canine adipocytes: stimulation of inflammatory adipokine production by LPS and TNFalpha.
Pflügers Archiv : European journal of physiology 2010;460(3):603-16.
2010: Alexander James German; Vivien H Ryan; Allison C German; I Stuart Wood; Paul Trayhurn
Obesity, its associated disorders and the role of inflammatory adipokines in companion animals.
Veterinary journal (London, England : 1997) 2010;185(1):4-9.
2010: T Mracek; D Gao; T Tzanavari; Y Bao; X Xiao; C Stocker; Paul Trayhurn; Chen Bing
Downregulation of zinc-{alpha}2-glycoprotein in adipose tissue and liver of obese ob/ob mice and by tumour necrosis factor-alpha in adipocytes.
The Journal of endocrinology 2010;204(2):165-72.
2010: Fátima Pérez de Heredia; I Stuart Wood; Paul Trayhurn
Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes.
Pflügers Archiv : European journal of physiology 2010;459(3):509-18.
2009: Paul Trayhurn
Obesity in the Inuit--adipose tissue and ischaemic heart disease.
International journal of circumpolar health 2009;68(5):419-20.
2009: Chen Bing; Paul Trayhurn
New insights into adipose tissue atrophy in cancer cachexia.
The Proceedings of the Nutrition Society 2009;68(4):385-92.
2009: I Stuart Wood; Fátima Pérez de Heredia; Bohan Wang; Paul Trayhurn
Cellular hypoxia and adipose tissue dysfunction in obesity.
The Proceedings of the Nutrition Society 2009;68(4):370-7.
2009: Alexander James German; M Hervera; L Hunter; S L Holden; Penelope Morris; V Biourge; Paul Trayhurn
Improvement in insulin resistance and reduction in plasma inflammatory adipokines after weight loss in obese dogs.
Domestic animal endocrinology 2009;37(4):214-26.
2009: Adrian O'Hara; Fei Ling Lim; Dawn J Mazzatti; Paul Trayhurn
Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium.
Pflügers Archiv : European journal of physiology 2009;458(6):1103-14.
2009: M P Thompson; Paul Trayhurn
Effect of salicylate on the expression of adipokines and glucose transporters in human adipocytes is modulated by hypoxia.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2009;41(8):649-52.
2009: I Stuart Wood; Bohan Wang; Paul Trayhurn
IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes.
Biochemical and biophysical research communications 2009;384(1):105-9.
2009: Qi Ding; Tomas Mracek; Pedro Gonzalez-Muniesa; Katarina Kos; John Wilding; Paul Trayhurn; Chen Bing
Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes.
Endocrinology 2009;150(4):1688-96.
2009: Martin Leuwer; Ingeborg Welters; Gernot Marx; Andrew Rushton; Hongguang Bao; Leif Hunter; Paul Trayhurn
Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice.
Pflügers Archiv : European journal of physiology 2009;457(4):731-41.
2009: Paul Trayhurn
Brown fat - hotting up again.
Obesity facts 2009;2(3):143-5.
2008: V H Ryan; Alexander James German; I Stuart Wood; L Hunter; Penelope Morris; Paul Trayhurn
NGF gene expression and secretion by canine adipocytes in primary culture: upregulation by the inflammatory mediators LPS and TNFalpha.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(12):861-8.
2008: Paul Trayhurn; Bohan Wang; I Stuart Wood
Hypoxia and the endocrine and signalling role of white adipose tissue.
Archives of physiology and biochemistry 2008;114(4):267-76.
2008: Paul Trayhurn; Bohan Wang; I Stuart Wood
HIF-1alpha protein rather than mRNA as a marker of hypoxia in adipose tissue in obesity: focus on "inflammation is associated with a decrease of lipogenic factors in omental fat in women," by Poulain-Godefroy et al.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(4):R1097; author reply R1098.
2008: Paul Trayhurn; Bohan Wang; I Stuart Wood
Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?
The British journal of nutrition 2008;100(2):227-35.
2008: Bohan Wang; I Stuart Wood; Paul Trayhurn
Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes.
The Journal of endocrinology 2008;198(1):127-34.
2008: Sarah Dutton; Paul Trayhurn
Regulation of angiopoietin-like protein 4/fasting-induced adipose factor (Angptl4/FIAF) expression in mouse white adipose tissue and 3T3-L1 adipocytes.
The British journal of nutrition 2008;100(1):18-26.
2008: Chen Bing; Paul Trayhurn
Regulation of adipose tissue metabolism in cancer cachexia.
Current opinion in clinical nutrition and metabolic care 2008;11(3):201-7.
2008: Bohan Wang; I Stuart Wood; Paul Trayhurn
PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes.
Biochemical and biophysical research communications 2008;368(1):88-93.
2007: Theodora Tzanavari; Chen Bing; Paul Trayhurn
Postnatal expression of zinc-alpha2-glycoprotein in rat white and brown adipose tissue.
Molecular and cellular endocrinology 2007;279(1-2):26-33.
2007: Bohan Wang; I Stuart Wood; Paul Trayhurn
Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes.
Pflügers Archiv : European journal of physiology 2007;455(3):479-92.
2007: I Stuart Wood; Bohan Wang; Silvia Lorente-Cebrián; Paul Trayhurn
Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-D-glucose uptake in human adipocytes.
Biochemical and biophysical research communications 2007;361(2):468-73.
2007: Mònica Bulló; Muhammad R Peeraully; Paul Trayhurn; J Folch; Jordi Salas-Salvadó
Circulating nerve growth factor levels in relation to obesity and the metabolic syndrome in women.
European journal of endocrinology / European Federation of Endocrine Societies 2007;157(3):303-10.
2007: Paul Trayhurn; Bohan Wang; I Stuart Wood
Comment on: Hosagai et al. (2007) Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation: Diabetes 56:901-911.
Diabetes 2007;56(9):e14.
2007: Paul Trayhurn
Adipocyte biology.
Obesity reviews : an official journal of the International Association for the Study of Obesity 2007;8 Suppl 1():41-4.
2007: Michael A Lomax; Fouzia Sadiq; Georgios Karamanlidis; Angeliki Karamitri; Paul Trayhurn; David G Hazlerigg
Ontogenic loss of brown adipose tissue sensitivity to beta-adrenergic stimulation in the ovine.
Endocrinology 2007;148(1):461-8.
2006: Muhammad R Peeraully; Henning Sievert; Mònica Bulló; Bohan Wang; Paul Trayhurn
Prostaglandin D2 and J2-series (PGJ2, Delta12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes.
Pflügers Archiv : European journal of physiology 2006;453(2):177-87.
2006: Myoung-Sool Do; Hun-Soon Jeong; Bong-Hyuk Choi; Leif Hunter; Stuart Langley; Laszlo Pazmany; Paul Trayhurn
Inflammatory gene expression patterns revealed by DNA microarray analysis in TNF-alpha-treated SGBS human adipocytes.
Yonsei medical journal 2006;47(5):729-36.
2006: Chen Bing; S Russell; E Becket; M Pope; Michael J Tisdale; Paul Trayhurn; John R Jenkins
Adipose atrophy in cancer cachexia: morphologic and molecular analysis of adipose tissue in tumour-bearing mice.
British journal of cancer 2006;95(8):1028-37.
2006: Paul Trayhurn; Chen Bing
Appetite and energy balance signals from adipocytes.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2006;361(1471):1237-49.
2006: Paul Trayhurn; Chen Bing; I Stuart Wood
Adipose tissue and adipokines--energy regulation from the human perspective.
The Journal of nutrition 2006;136(7 Suppl):1935S-1939S.
2006: Bohan Wang; Paul Trayhurn
Acute and prolonged effects of TNF-alpha on the expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture.
Pflügers Archiv : European journal of physiology 2006;452(4):418-27.
2005: I Stuart Wood; Bohan Wang; John R Jenkins; Paul Trayhurn
The pro-inflammatory cytokine IL-18 is expressed in human adipose tissue and strongly upregulated by TNFalpha in human adipocytes.
Biochemical and biophysical research communications 2005;337(2):422-9.
2005: Paul Trayhurn; I S Wood
Signalling role of adipose tissue: adipokines and inflammation in obesity.
Biochemical Society transactions 2005;33(Pt 5):1078-81.
2005: Paul Trayhurn
Tempus fugit--evolution and current impact of the British Journal of Nutrition.
The British journal of nutrition 2005;94(3):299-301.
2005: I Eisele; I S Wood; Alexander James German; L Hunter; Paul Trayhurn
Adipokine gene expression in dog adipose tissues and dog white adipocytes differentiated in primary culture.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(8):474-81.
2005: Paul Trayhurn
Endocrine and signalling role of adipose tissue: new perspectives on fat.
Acta physiologica Scandinavica 2005;184(4):285-93.
2005: Paul Trayhurn
White adipose tissue grafts--keeping in contact.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(2):R297-R298.
2005: Mònica Bulló; Muhammad R Peeraully; Paul Trayhurn
Stimulation of NGF expression and secretion in 3T3-L1 adipocytes by prostaglandins PGD2, PGJ2, and Delta12-PGJ2.
American journal of physiology. Endocrinology and metabolism 2005;289(1):E62-7.
2005: Bohan Wang; John R Jenkins; Paul Trayhurn
Expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture: integrated response to TNF-alpha.
American journal of physiology. Endocrinology and metabolism 2005;288(4):E731-40.
2005: Paul Trayhurn
Adipose tissue in obesity--an inflammatory issue.
Endocrinology 2005;146(3):1003-5.
2005: Paul Trayhurn
The biology of obesity.
The Proceedings of the Nutrition Society 2005;64(1):31-8.
2005: Yi Bao; Chen Bing; Leif Hunter; John R Jenkins; Martin Wabitsch; Paul Trayhurn
Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed and secreted by human (SGBS) adipocytes.
FEBS letters 2005;579(1):41-7.
2005: Paul Trayhurn
Obesity -- what role now for nutritional science?
The British journal of nutrition 2005;93(1):1-2.
2004: Paul Trayhurn; I Stuart Wood
Adipokines: inflammation and the pleiotropic role of white adipose tissue.
The British journal of nutrition 2004;92(3):347-55.
2004: Muhammad R Peeraully; John R Jenkins; Paul Trayhurn
NGF gene expression and secretion in white adipose tissue: regulation in 3T3-L1 adipocytes by hormones and inflammatory cytokines.
American journal of physiology. Endocrinology and metabolism 2004;287(2):E331-9.
2004: Chen Bing; Yi Bao; John Jenkins; Paul Sanders; Monia Manieri; Saverio Cinti; Michael J Tisdale; Paul Trayhurn
Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2500-5.
2004: Claudia Oller do Nascimento; Leif Hunter; Paul Trayhurn
Regulation of haptoglobin gene expression in 3T3-L1 adipocytes by cytokines, catecholamines, and PPARgamma.
Biochemical and biophysical research communications 2004;313(3):702-8.
2004: Paul Trayhurn
Of genes and genomes - and dark matter.
The British journal of nutrition 2004;91(1):1-2.
2003: I Stuart Wood; Leif Hunter; Paul Trayhurn
Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues.
Biochemical and biophysical research communications 2003;308(1):43-9.
2003: Paul Trayhurn
Recent highly cited articles in the British Journal of Nutrition.
The British journal of nutrition 2003;90(1):1-2.
2003: Paul Trayhurn
Leptin--a critical body weight signal and a "master" hormone?
Science's STKE : signal transduction knowledge environment 2003;2003(169):PE7.
2003: I Stuart Wood; Paul Trayhurn
Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins.
The British journal of nutrition 2003;89(1):3-9.
2003: Paul Trayhurn
Nutritional genomics - "Nutrigenomics".
The British journal of nutrition 2003;89(1):1-2.
2002: J Gómez-Ambrosi; Natalia Zabalegui; Chen Bing; Michael J Tisdale; Paul Trayhurn; Gareth Williams
Weight loss in tumour-bearing mice is not associated with changes in resistin gene expression in white adipose tissue.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):674-7.
2002: Chen Bing; Javier Gomez-Ambrosi; Natalia Zabalegui; Gareth Williams; Paul Trayhurn
Resistin and RELM-alpha gene expression in white adipose tissue of lactating mice.
Biochemical and biophysical research communications 2002;296(2):458-62.
2002: Myoung-Sool Do; S-Y Nam; Seong-Eui Hong; K W Kim; JS Duncan; JH Beattie; Paul Trayhurn
Metallothionein gene expression in human adipose tissue from lean and obese subjects.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(6):348-51.
2002: Paul Trayhurn
The public library of science and "open access" to the scientific literature.
The British journal of nutrition 2002;87(1):1-2.
2001: Fred Haugen; A Jørgensen; Christian Andre Drevon; Paul Trayhurn
Inhibition by insulin of resistin gene expression in 3T3-L1 adipocytes.
FEBS letters 2001;507(1):105-8.
2001: Paul Trayhurn
Michael J Stock (1942-2001): an appreciation.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(9):1269-71.
2001: Paul Trayhurn; JH Beattie
Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ.
The Proceedings of the Nutrition Society 2001;60(3):329-39.
2001: Paul Trayhurn
Biology of leptin--its implications and consequences for the treatment of obesity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25 Suppl 1():S26-8.
2001: D V Rayner; Paul Trayhurn
Regulation of leptin production: sympathetic nervous system interactions.
Journal of molecular medicine (Berlin, Germany) 2001;79(1):8-20.
2000: Paul Trayhurn; JS Duncan; AM Wood; JH Beattie
Metallothionein gene expression and secretion in white adipose tissue.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(6):R2329-35.
2000: Paul Trayhurn; JS Duncan; AM Wood; JH Beattie
Regulation of metallothionein gene expression and secretion in rat adipocytes differentiated from preadipocytes in primary culture.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(11-12):542-7.
2000: JH Beattie; AM Wood; Paul Trayhurn; B Jasani; A Vincent; G McCormack; A K West
Metallothionein is expressed in adipocytes of brown fat and is induced by catecholamines and zinc.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;278(4):R1082-9.
2000: Nigel Hoggard; L Hunter; Richard G Lea; Paul Trayhurn; J G Mercer
Ontogeny of the expression of leptin and its receptor in the murine fetus and placenta.
The British journal of nutrition 2000;83(3):317-26.
1999: Myoung-Sool Do; Jong Bae Kim; Taek Joon Yoon; CH Park; D Vernon Rayner; Paul Trayhurn
Induction of uncoupling protein-2 (UCP2) gene expression on the differentiation of rat preadipocytes to adipocytes in primary culture.
Molecules and cells 1999;9(1):20-4.
1999: Paul Trayhurn; N Hoggard; Julian G Mercer; D V Rayner
Leptin: fundamental aspects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23 Suppl 1():22-8.
1998: D Finn; M A Lomax; Paul Trayhurn
An immunohistochemical and in situ hybridisation study of the postnatal development of uncoupling protein-1 and uncoupling protein-1 mRNA in lamb perirenal adipose tissue.
Cell and tissue research 1998;294(3):461-6.
1998: N Hoggard; L Hunter; Paul Trayhurn; Lynda M Williams; Julian G Mercer
Leptin and reproduction.
The Proceedings of the Nutrition Society 1998;57(3):421-7.
1998: Paul Trayhurn; JS Duncan; N Hoggard; D V Rayner
Regulation of leptin production: a dominant role for the sympathetic nervous system?
The Proceedings of the Nutrition Society 1998;57(3):413-9.
1998: D V Rayner; E Simón; J S Duncan; Paul Trayhurn
Hyperleptinaemia in mice induced by administration of the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine.
FEBS letters 1998;429(3):395-8.
1998: D V Rayner; T Atkinson; G D Dalgleish; JS Duncan; N Hoggard; Paul Trayhurn
Hyperleptinaemia precedes hyperinsulinaemia in Zucker (fa/fa) rats.
Biochemical Society transactions 1998;26(2):S98.
1998: JH Beattie; AM Wood; A M Newman; I Bremner; KH Choo; AE Michalska; JS Duncan; Paul Trayhurn
Obesity and hyperleptinemia in metallothionein (-I and -II) null mice.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):358-63.
1998: Paul Trayhurn; N Hoggard; Julian G Mercer; D V Rayner
Hormonal and neuroendocrine regulation of energy balance--the role of leptin.
Archiv für Tierernährung 1998;51(2-3):177-85.
1997: N Hoggard; L Hunter; J S Duncan; L M Williams; Paul Trayhurn; J G Mercer
Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):11073-8.
1997: Chen Bing; Lucy C Pickavance; Q Wang; HM Frankish; Paul Trayhurn; Gareth Williams
Role of hypothalamic neuropeptide Y neurons in the defective thermogenic response to acute cold exposure in fatty Zucker rats.
Neuroscience 1997;80(1):277-84.
1997: D V Rayner; G D Dalgliesh; JS Duncan; LJ Hardie; N Hoggard; Paul Trayhurn
Postnatal development of the ob gene system: elevated leptin levels in suckling fa/fa rats.
The American journal of physiology 1997;273(1 Pt 2):R446-50.
1997: N Hoggard; Julian G Mercer; D V Rayner; Kim M Moar; Paul Trayhurn; Lynda M Williams
Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization.
Biochemical and biophysical research communications 1997;232(2):383-7.
1997: Q Wang; Chen Bing; Kamal A Al-Barazanji; D E Mossakowaska; X M Wang; DL McBay; W A Neville; M Taddayon; Lucy C Pickavance; S Dryden; M E Thomas; M T McHale; I S Gloyer; S Wilson; RE Buckingham; Jonathan R S Arch; Paul Trayhurn; Gareth Williams
Interactions between leptin and hypothalamic neuropeptide Y neurons in the control of food intake and energy homeostasis in the rat.
Diabetes 1997;46(3):335-41.
1997: Julian G Mercer; Kim M Moar; D Vernon Rayner; Paul Trayhurn; N Hoggard
Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice.
FEBS letters 1997;402(2-3):185-8.
1997: S E Mitchell; W D Rees; LJ Hardie; N Hoggard; Moh Tadayyon; J R Arch; Paul Trayhurn
ob gene expression and secretion of leptin following differentiation of rat preadipocytes to adipocytes in primary culture.
Biochemical and biophysical research communications 1997;230(2):360-4.
1996: L J Hardie; N Guilhot; Paul Trayhurn
Regulation of leptin production in cultured mature white adipocytes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(12):685-9.
1996: Paul Trayhurn; JS Duncan; D V Rayner; L J Hardie
Rapid inhibition of ob gene expression and circulating leptin levels in lean mice by the beta 3-adrenoceptor agonists BRL 35135A and ZD2079.
Biochemical and biophysical research communications 1996;228(2):605-10.
1996: Paul Trayhurn
New insights into the development of obesity: obese genes and the leptin system.
The Proceedings of the Nutrition Society 1996;55(3):783-91.
1996: Julian G Mercer; N Hoggard; Lynda M Williams; C B Lawrence; Lisa T Hannah; P J Morgan; Paul Trayhurn
Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus.
Journal of neuroendocrinology 1996;8(10):733-5.
1996: L J Hardie; D V Rayner; S Holmes; Paul Trayhurn
Circulating leptin levels are modulated by fasting, cold exposure and insulin administration in lean but not Zucker (fa/fa) rats as measured by ELISA.
Biochemical and biophysical research communications 1996;223(3):660-5.
1996: Julian G Mercer; N Hoggard; Lynda M Williams; C B Lawrence; Lisa T Hannah; Paul Trayhurn
Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization.
FEBS letters 1996;387(2-3):113-6.
1996: J H Beattie; D J Black; AM Wood; Paul Trayhurn
Cold-induced expression of the metallothionein-1 gene in brown adipose tissue of rats.
The American journal of physiology 1996;270(5 Pt 2):R971-7.
1996: J H Beattie; D Shand; AM Wood; Paul Trayhurn
Metallothionein gene expression in brown adipose tissue.
Biochemical Society transactions 1996;24(2):159S.
1996: I Rubio-Aliaga; Paul Trayhurn
Expression of the ob (obese) gene during lactation in mice.
Biochemical Society transactions 1996;24(2):157S.
1996: D V Rayner; Paul Trayhurn
Ob (obese) gene expression in white adipose tissue of obese Zucker (fa/fa) rats.
Biochemical Society transactions 1996;24(2):156S.
1996: Paul Trayhurn; D V Rayner
Hormones and the ob gene product (leptin) in the control of energy balance.
Biochemical Society transactions 1996;24(2):565-70.
1996: Paul Trayhurn
Uncoupling protein in brown adipose tissue: molecular differentiation of the adipose tissues.
Biochemical Society transactions 1996;24(2):402-6.
1996: Paul Trayhurn
Northern blotting.
The Proceedings of the Nutrition Society 1996;55(1B):583-9.
1996: Chen Bing; HM Frankish; Q Wang; D Hopkins; J Keith; Paul Trayhurn; Gareth Williams
Dissociation of hypothalamic NPY from BAT uncoupling protein mRNA in rats exposed to 24 h thermoneutrality.
The American journal of physiology 1996;270(1 Pt 2):R111-7.
1995: Paul Trayhurn; JS Duncan; D V Rayner
Acute cold-induced suppression of ob (obese) gene expression in white adipose tissue of mice: mediation by the sympathetic system.
The Biochemical journal 1995;311 ( Pt 3)():729-33.
1995: Paul Trayhurn; M E Thomas; JS Duncan; D Black; J H Beattie; D V Rayner
Ultra-rapid detection of mRNAs on northern blots with digoxigenin-labelled oligonucleotides and 'CDP-Star', a new chemiluminescence substrate.
Biochemical Society transactions 1995;23(3):494S.
1995: Paul Trayhurn; M E Thomas; JS Duncan; D V Rayner
Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (oblob) mice.
FEBS letters 1995;368(3):488-90.
1995: Paul Trayhurn; JS Duncan; A Nestor; M E Thomas; N C Eastmond; D V Rayner
Rapid chemiluminescent detection of mRNAs on northern blots with digoxigenin end-labelled oligonucleotides.
Electrophoresis 1995;16(3):341-4.
1995: Paul Trayhurn
Fuel selection in brown adipose tissue.
The Proceedings of the Nutrition Society 1995;54(1):39-47.
1994: Paul Trayhurn; JS Duncan; A Nestor; M E Thomas; D V Rayner
Chemiluminescent detection of mRNAs on northern blots with digoxigenin end-labeled oligonucleotides.
Analytical biochemistry 1994;222(1):224-30.
1994: Julian G Mercer; J S Duncan; C B Lawrence; Paul Trayhurn
Effect of photoperiod on mitochondrial GDP binding and adenylate cyclase activity in brown adipose tissue of Djungarian hamsters.
Physiology & behavior 1994;56(4):737-40.
1994: D V Rayner; M E Thomas; A Nestor; Paul Trayhurn
Rapid chemiluminescent detection of facilitative glucose transporter mRNAs (GLUTs 1-4) with digoxigenin end-labelled oligonucleotides.
Biochemical Society transactions 1994;22(3):273S.
1994: Fergus Nicol; H Lefranc; John R Arthur; Paul Trayhurn
Characterization and postnatal development of 5'-deiodinase activity in goat perirenal fat.
The American journal of physiology 1994;267(1 Pt 2):R144-9.
1994: Paul Trayhurn; JS Duncan
Rapid chemiluminescent detection of the mRNA for uncoupling protein in brown adipose tissue by northern hybridization with a 32-mer oligonucleotide end-labelled with digoxigenin.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1994;18(6):449-52.
1994: JS Duncan; S Lyke; Paul Trayhurn
Chemiluminescent detection of uncoupling protein mRNA on northern blots with a digoxigenin (DIG) end-labelled oligonucleotide.
Biochemical Society transactions 1994;22(2):161S.
1994: D V Rayner; M E Thomas; Paul Trayhurn
Glucose transporters (GLUTs 1-4) and their mRNAs in regions of the rat brain: insulin-sensitive transporter expression in the cerebellum.
Canadian journal of physiology and pharmacology 1994;72(5):476-9.
1993: Paul Trayhurn; M E Thomas; J S Keith
Postnatal development of uncoupling protein, uncoupling protein mRNA, and GLUT4 in adipose tissues of goats.
The American journal of physiology 1993;265(3 Pt 2):R676-82.
1993: AK Dutta-Roy; Y Huang; B Dunbar; Paul Trayhurn
Purification and characterization of fatty acid-binding proteins from brown adipose tissue of the rat.
Biochimica et biophysica acta 1993;1169(1):73-9.
1993: Paul Trayhurn; M E Thomas; JS Duncan; Fergus Nicol; John R Arthur
Presence of the brown fat-specific mitochondrial uncoupling protein and iodothyronine 5'-deiodinase activity in subcutaneous adipose tissue of neonatal lambs.
FEBS letters 1993;322(1):76-8.
1993: H D McCarthy; A P Kilpatrick; Paul Trayhurn; Gareth Williams
Widespread increases in regional hypothalamic neuropeptide Y levels in acute cold-exposed rats.
Neuroscience 1993;54(1):127-32.
1993: F Brander; J S Keith; Paul Trayhurn
A 27-mer oligonucleotide probe for the detection and measurement of the mRNA for uncoupling protein in brown adipose tissue of different species.
Comparative biochemistry and physiology. B, Comparative biochemistry 1993;104(1):125-31.
1992: R M Knott; Paul Trayhurn; John Hesketh
Changes in insulin-receptor mRNA levels in skeletal muscle and brown adipose tissue of weanling rats during fasting and refeeding.
The British journal of nutrition 1992;68(3):583-92.
1992: Fergus Nicol; H Lefranc; John R Arthur; Paul Trayhurn
Types I and II iodothyronine 5'-deiodinase activities in perirenal brown adipose tissue of neonatal goats.
Biochemical Society transactions 1992;20(4):336S.
1992: Paul Trayhurn; M E Thomas; J S Keith
Early postnatal changes in the brown fat-specific mitochondrial uncoupling protein in goat adipose tissues.
Biochemical Society transactions 1992;20(4):335S.
1991: John R Arthur; Fergus Nicol; Geoffrey J Beckett; Paul Trayhurn
Impairment of iodothyronine 5'-deiodinase activity in brown adipose tissue and its acute stimulation by cold in selenium deficiency.
Canadian journal of physiology and pharmacology 1991;69(6):782-5.
1991: Paul Trayhurn; J S Keith; P A Racey; A M Burnett
Immunological identification of uncoupling protein in interscapular "brown" adipose tissue of suckling and adult pipistrelle bats (Pipistrellus pipistrellus).
Comparative biochemistry and physiology. B, Comparative biochemistry 1991;99(2):317-20.
1990: A Géloën; John R Arthur; Geoffrey J Beckett; Paul Trayhurn
Effect of selenium and iodine deficiency on the level of uncoupling protein in brown adipose tissue of rats.
Biochemical Society transactions 1990;18(6):1269-70.
1990: R M Knott; John Hesketh; Paul Trayhurn
Insulin receptor gene expression in skeletal muscle and brown adipose tissue.
Biochemical Society transactions 1990;18(6):1263.
1990: F Macfarlane; Paul Trayhurn
Oligonucleotide probe for the cross-species measurement of the mRNA for uncoupling protein in brown adipose tissue.
Biochemical Society transactions 1990;18(6):1261.
1990: A Géloën; Paul Trayhurn
Regulation of the level of uncoupling protein in brown adipose tissue by insulin requires the mediation of the sympathetic nervous system.
FEBS letters 1990;267(2):265-7.