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Jacques Tremblay

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Daniel Skuk; Marlyne Goulet; Martin Paradis; Jacques P Tremblay
Myopathy in a rhesus monkey with biopsy findings similar to human sporadic inclusion body myositis.
Basma F Benabdallah; Pierre Chapdelaine; Arnaud Duval; Eli Haddad; Michael C Holmes; Joel Rousseau; Jacques P Tremblay; Christian M Beauséjour
Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation.
Daniel Skuk; Jacques P Tremblay
Necrosis, sarcolemmal damage and apoptotic events in myofibers rejected by CD8+ lymphocytes: Observations in nonhuman primates.

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All Publications

2013: Daniel Skuk; Marlyne Goulet; Martin Paradis; Jacques P Tremblay
Myopathy in a rhesus monkey with biopsy findings similar to human sporadic inclusion body myositis.
Neuromuscular disorders : NMD 2013;23(2):155-9.
2013: Basma F Benabdallah; Pierre Chapdelaine; Arnaud Duval; Eli Haddad; Michael C Holmes; Joel Rousseau; Jacques P Tremblay; Christian M Beauséjour
Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation.
Molecular therapy. Nucleic acids 2013;2():e68.
2012: Daniel Skuk; Jacques P Tremblay
Necrosis, sarcolemmal damage and apoptotic events in myofibers rejected by CD8+ lymphocytes: Observations in nonhuman primates.
Neuromuscular disorders : NMD 2012;22(11):997-1005.
2012: Catherine Gérard; Sébastien Goudenege; Daniel Skuk; Christine Dufour; Jacques P Tremblay
AG490 improves the survival of human myoblasts in vitro and in vivo.
Cell transplantation 2012;21(12):2665-76.
2012: Raouia Fakhfakh; Se-Jin Lee; Jacques P Tremblay
Administration of a soluble activin type IIB receptor promotes the transplantation of human myoblasts in dystrophic mice.
Cell transplantation 2012;21(7):1419-30.
2012: Christophe Pichavant; Jacques P Tremblay
Generation of lentiviral vectors for use in skeletal muscle research.
Methods in molecular biology (Clifton, N.J.) 2012;798():285-95.
2012: Catherine Gerard; Daniel Skuk; Genevieve Beauregard; Marie Anne Forest; Jacques P Tremblay
Fibrin gel improves the survival of transplanted myoblasts.
Cell transplantation 2012;21(1):127-37.
2011: Jacques P Tremblay; Robert M Frederickson
Gene transfer using HACs: a key step closer to ex vivo gene therapy using autologous gene-corrected cells to treat muscular dystrophy.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(12):2111-3.
2011: Daniel Skuk; Marlyne Goulet; Jacques P Tremblay
Transplanted myoblasts can migrate several millimeters to fuse with damaged myofibers in nonhuman primate skeletal muscle.
Journal of neuropathology and experimental neurology 2011;70(9):770-8.
2011: Christophe Pichavant; Annemieke Aartsma-Rus; Paula R Clemens; Kay E Davies; George Dickson; Shin'ichi Takeda; Steve D Wilton; Jon A Wolff; Christine I Wooddell; Xiao Xiao; Jacques P Tremblay
Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(5):830-40.
2011: Daniel Skuk; Jacques P Tremblay
Intramuscular cell transplantation as a potential treatment of myopathies: clinical and preclinical relevant data.
Expert opinion on biological therapy 2011;11(3):359-74.
2011: Christophe Pichavant; Cesare Gargioli; Jacques P Tremblay
Intramuscular Transplantation of Muscle Precursor Cells over-expressing MMP-9 improves Transplantation Success.
PLoS currents 2011;3():RRN1275.
2011: Jacques P Tremblay; Daniel Skuk; Robert Frederickson
Not an inside job: how can transplantation of relatively few exogenous satellite cells do what thousands of endogenous cells cannot?
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(1):6-8.
2010: Daniel Skuk; Martin Paradis; Marlyne Goulet; Pierre Chapdelaine; David M Rothstein; Jacques P Tremblay
Intramuscular transplantation of human postnatal myoblasts generates functional donor-derived satellite cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(9):1689-97.
2010: Pierre Chapdelaine; C Pichavant; Joël Rousseau; F Pâques; Jacques P Tremblay
Meganucleases can restore the reading frame of a mutated dystrophin.
Gene therapy 2010;17(7):846-58.
2010: Thomas Paccalet; Zoé Coulombe; Jacques P Tremblay
Ganglioside GM3 levels are altered in a mouse model of HIBM: GM3 as a cellular marker of the disease.
PloS one 2010;5(4):e10055.
2010: Pierre-Luc Richard; Clément Gosselin; Thierry Laliberté; Martin Paradis; Marlyne Goulet; Jacques P Tremblay; Daniel Skuk
A first semimanual device for clinical intramuscular repetitive cell injections.
Cell transplantation 2010;19(1):67-78.
2009: Jacques P Tremblay; Daniel Skuk; Benjamino Palmieri; David M Rothstein
A case for immunosuppression for myoblast transplantation in duchenne muscular dystrophy.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(7):1122-4.
2009: Jean Francois Lafreniere; Marie-Christine Caron; Daniel Skuk; Marlyne Goulet; Anissa Rahma Cheikh; Jacques P Tremblay
Growth factor coinjection improves the migration potential of monkey myogenic precursors without affecting cell transplantation success.
Cell transplantation 2009;18(7):719-30.
2009: Basma F Benabdallah; Dr Manaf Bouchentouf; Joël Rousseau; Jacques P Tremblay
Overexpression of follistatin in human myoblasts increases their proliferation and differentiation, and improves the graft success in SCID mice.
Cell transplantation 2009;18(7):709-18.
2008: Jacques P Tremblay; Daniel Skuk
Another new "super muscle stem cell" leaves unaddressed the real problems of cell therapy for duchenne muscular dystrophy.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(12):1907-9.
2008: Geoffrey Camirand; Lionel Stéphan; Joël Rousseau; Mélanie K Sackett; Nicolas J Caron; Philippe Mills; Josef Kurtz; Megan Sykes; David M Rothstein; Jacques P Tremblay
Central tolerance to myogenic cell transplants does not include muscle neoantigens.
Transplantation 2008;85(12):1791-801.
2008: Basma F Benabdallah; Dr Manaf Bouchentouf; Joël Rousseau; Pascal Bigey; Annick Michaud; Pierre Chapdelaine; Daniel Scherman; Jacques P Tremblay
Inhibiting myostatin with follistatin improves the success of myoblast transplantation in dystrophic mice.
Cell transplantation 2008;17(3):337-50.
2007: Daniel Skuk; Martin Paradis; Marlyne Goulet; Jacques P Tremblay
Ischemic central necrosis in pockets of transplanted myoblasts in nonhuman primates: implications for cell-transplantation strategies.
Transplantation 2007;84(10):1307-15.
2007: Philippe Mills; J C Dominique; J F Lafrenière; Dr Manaf Bouchentouf; Jacques P Tremblay
A synthetic mechano growth factor E Peptide enhances myogenic precursor cell transplantation success.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(10):2247-59.
2007: Dr Manaf Bouchentouf; Basma F Benabdallah; J Rousseau; L M Schwartz; Jacques P Tremblay
Induction of Anoikis following myoblast transplantation into SCID mouse muscles requires the Bit1 and FADD pathways.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(6):1491-505.
2007: Bruno Péault; Michael Rudnicki; Yvan Torrente; Giulio Cossu; Jacques P Tremblay; Terry Partridge; Emanuela Gussoni; Louis Kunkel; Johnny Huard
Stem and progenitor cells in skeletal muscle development, maintenance, and therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(5):867-77.
2007: Simon P Quenneville; Pierre Chapdelaine; Joël Rousseau; Jacques P Tremblay
Dystrophin expression in host muscle following transplantation of muscle precursor cells modified with the phiC31 integrase.
Gene therapy 2007;14(6):514-22.
2007: Simon P Quenneville; Pierre Chapdelaine; Daniel Skuk; Martin Paradis; Marlyne Goulet; Joël Rousseau; Xiao Xiao; Luis Garcia; Jacques P Tremblay
Autologous transplantation of muscle precursor cells modified with a lentivirus for muscular dystrophy: human cells and primate models.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(2):431-8.
2007: Philippe Mills; Jean-François Lafrenière; Basma F Benabdallah; elmostafa El fahime; Jacques P Tremblay
A new pro-migratory activity on human myogenic precursor cells for a synthetic peptide within the E domain of the mechano growth factor.
Experimental cell research 2007;313(3):527-37.
2007: Lionel Stephan; Dr Manaf Bouchentouf; Philippe Mills; Jean-François Lafreniere; Jacques P Tremblay
1,25-dihydroxyvitamin D3 increases the transplantation success of human muscle precursor cells in SCID mice.
Cell transplantation 2007;16(4):391-402.
2007: Daniel Skuk; Marlyne Goulet; Brigitte Roy; Vincent Piette; Claude H Côté; Pierre Chapdelaine; Jean-Yves Hogrel; Martin Paradis; Jean-Pierre Bouchard; Michel Sylvain; Jean-Guy Lachance; Jacques P Tremblay
First test of a "high-density injection" protocol for myogenic cell transplantation throughout large volumes of muscles in a Duchenne muscular dystrophy patient: eighteen months follow-up.
Neuromuscular disorders : NMD 2007;17(1):38-46.
2006: Jacques P Tremblay
CSCI/RCPSC Henry Friesen Lecture: Cell therapy for Duchenne muscular dystrophy.
Clinical and investigative medicine. Médecine clinique et experimentale 2006;29(6):378-82.
2006: Simon P Quenneville; Jacques P Tremblay
Ex vivo modification of cells to induce a muscle-based expression.
Current gene therapy 2006;6(6):625-32.
2006: Dr Manaf Bouchentouf; Basma F Benabdallah; Philippe Mills; Jacques P Tremblay
Exercise improves the success of myoblast transplantation in mdx mice.
Neuromuscular disorders : NMD 2006;16(8):518-29.
2006: Pierre Chapdelaine; Jihong Kang; Sofia Boucher-Kovalik; Nicolas J Caron; Jacques P Tremblay; Michel A Fortier
Decidualization and maintenance of a functional prostaglandin system in human endometrial cell lines following transformation with SV40 large T antigen.
Molecular human reproduction 2006;12(5):309-19.
2006: Jean Francois Lafreniere; Philippe Mills; Dr Manaf Bouchentouf; Jacques P Tremblay
Interleukin-4 improves the migration of human myogenic precursor cells in vitro and in vivo.
Experimental cell research 2006;312(7):1127-41.
2006: Daniel Skuk; Marlyne Goulet; Brigitte Roy; Pierre Chapdelaine; Jean-Pierre Bouchard; Raynald Roy; Francine J Dugré; Michel Sylvain; Jean-Guy Lachance; Louise Deschênes; Hélène Senay; Jacques P Tremblay
Dystrophin expression in muscles of duchenne muscular dystrophy patients after high-density injections of normal myogenic cells.
Journal of neuropathology and experimental neurology 2006;65(4):371-86.
2006: Lionel Stephan; Christophe Pichavant; Dr Manaf Bouchentouf; Philippe Mills; Geoffrey Camirand; Saloua Tagmouti; David M Rothstein; Jacques P Tremblay
Induction of tolerance across fully mismatched barriers by a nonmyeloablative treatment excluding antibodies or irradiation use.
Cell transplantation 2006;15(8-9):835-46.
2006: Daniel Skuk; Marlyne Goulet; Jacques P Tremblay
Use of repeating dispensers to increase the efficiency of the intramuscular myogenic cell injection procedure.
Cell transplantation 2006;15(7):659-63.
2005: Basma F Benabdallah; Dr Manaf Bouchentouf; Jacques P Tremblay
Improved success of myoblast transplantation in mdx mice by blocking the myostatin signal.
Transplantation 2005;79(12):1696-702.
2005: Dr Manaf Bouchentouf; Basma F Benabdallah; Marcel Dumont; Joel Rousseau; Luc Jobin; Jacques P Tremblay
Real-time imaging of myoblast transplantation using the human sodium iodide symporter.
BioTechniques 2005;38(6):937-42.
2004: Simon P Quenneville; Pierre Chapdelaine; Joël Rousseau; Jean Beaulieu; Nicolas J Caron; Daniel Skuk; Philippe Mills; Eric C Olivares; Michele P Calos; Jacques P Tremblay
Nucleofection of muscle-derived stem cells and myoblasts with phiC31 integrase: stable expression of a full-length-dystrophin fusion gene by human myoblasts.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(4):679-87.
2004: Geoffrey Camirand; Joël Rousseau; Marie-Eve Ducharme; David M Rothstein; Jacques P Tremblay
Novel Duchenne muscular dystrophy treatment through myoblast transplantation tolerance with anti-CD45RB, anti-CD154 and mixed chimerism.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(8):1255-65.
2004: Nicolas J Caron; Simon P Quenneville; Jacques P Tremblay
Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins.
Biochemical and biophysical research communications 2004;319(1):12-20.
2004: Jean Francois Lafreniere; Philippe Mills; Jacques P Tremblay; elmostafa El fahime
Growth factors improve the in vivo migration of human skeletal myoblasts by modulating their endogenous proteolytic activity.
Transplantation 2004;77(11):1741-7.
2004: Dr Manaf Bouchentouf; Basma F Benabdallah; Jacques P Tremblay
Myoblast survival enhancement and transplantation success improvement by heat-shock treatment in mdx mice.
Transplantation 2004;77(9):1349-56.
2004: Daniel Skuk; Brigitte Roy; Marlyne Goulet; Pierre Chapdelaine; Jean-Pierre Bouchard; Raynald Roy; Francine J Dugré; Jean-Guy Lachance; Louise Deschênes; Senay Hélène; Michel Sylvain; Jacques P Tremblay
Dystrophin expression in myofibers of Duchenne muscular dystrophy patients following intramuscular injections of normal myogenic cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(3):475-82.
2003: Daniel Skuk; Jacques P Tremblay
Cell therapies for inherited myopathies.
Current opinion in rheumatology 2003;15(6):723-9.
2003: Daniel Skuk; Nicolas J Caron; Marlyne Goulet; Brigitte Roy; Jacques P Tremblay
Resetting the problem of cell death following muscle-derived cell transplantation: detection, dynamics and mechanisms.
Journal of neuropathology and experimental neurology 2003;62(9):951-67.
2003: Yvan Torrente; Geoffrey Camirand; Federica Pisati; Marzia Belicchi; Barbara Rossi; Fabio Riccardo Colombo; elmostafa El fahime; Nicolas J Caron; Andrew C Issekutz; Gabriela Constantin; Jacques P Tremblay; Nereo Bresolin
Identification of a putative pathway for the muscle homing of stem cells in a muscular dystrophy model.
The Journal of cell biology 2003;162(3):511-20.
2003: elmostafa El fahime; Dr Manaf Bouchentouf; Basma F Benabdallah; Daniel Skuk; Jean Francois Lafreniere; Y T Chang; Jacques P Tremblay
Tubulyzine, a novel tri-substituted triazine, prevents the early cell death of transplanted myogenic cells and improves transplantation success.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2003;81(2):81-90.
2003: Daniel Skuk; Jacques P Tremblay
Myoblast transplantation: the current status of a potential therapeutic tool for myopathies.
Journal of muscle research and cell motility 2003;24(4-6):285-300.
2003: Yvan Torrente; elmostafa El fahime; Nicolas J Caron; Roberto Del Bo; Marzia Belicchi; Federica Pisati; Jacques P Tremblay; Nereo Bresolin
Tumor necrosis factor-alpha (TNF-alpha) stimulates chemotactic response in mouse myogenic cells.
Cell transplantation 2003;12(1):91-100.
2002: elmostafa El fahime; Philippe Mills; Jean Francois Lafreniere; Yvan Torrente; Jacques P Tremblay
The urokinase plasminogen activator: an interesting way to improve myoblast migration following their transplantation.
Experimental cell research 2002;280(2):169-78.
2002: Daniel Skuk; Jean-Thomas Vilquin; Jacques P Tremblay
Experimental and therapeutic approaches to muscular dystrophies.
Current opinion in neurology 2002;15(5):563-9.
2002: Joel Rousseau; Bernard Têtu; Danielle Caron; Patrick Malenfant; Paola Cattaruzzi; Marie Audette; Charles Doillon; Jacques P Tremblay; Benoit Guérette
RCAS1 is associated with ductal breast cancer progression.
Biochemical and biophysical research communications 2002;293(5):1544-9.
2002: Daniel Skuk; Marlyne Goulet; Brigitte Roy; Jacques P Tremblay
Efficacy of myoblast transplantation in nonhuman primates following simple intramuscular cell injections: toward defining strategies applicable to humans.
Experimental neurology 2002;175(1):112-26.
2002: Geoffrey Camirand; Nicolas J Caron; Nicole A Turgeon; Aldo A Rossini; Jacques P Tremblay
Treatment with anti-CD154 antibody and donor-specific transfusion prevents acute rejection of myoblast transplantation.
Transplantation 2002;73(3):453-61.
2002: K Leriche-Guérin; Louise V B Anderson; Klaus Wrogemann; Brigitte Roy; Marlyne Goulet; Jacques P Tremblay
Dysferlin expression after normal myoblast transplantation in SCID and in SJL mice.
Neuromuscular disorders : NMD 2002;12(2):167-73.
2002: Mathieu Bujold; Nicolas J Caron; Goeffrey Camiran; Santwana Mukherjee; Paul D Allen; Jacques P Tremblay; Yaming Wang
Autotransplantation in mdx mice of mdx myoblasts genetically corrected by an HSV-1 amplicon vector.
Cell transplantation 2002;11(8):759-67.
2002: Daniel Skuk; Nicolas J Caron; Marlyne Goulet; Brigitte Roy; Francisco Espinosa; Jacques P Tremblay
Dynamics of the early immune cellular reactions after myogenic cell transplantation.
Cell transplantation 2002;11(7):671-81.
2001: Philippe Campeau; Pierre Chapdelaine; Sophie Seigneurin-Venin; B Massie; Jacques P Tremblay
Transfection of large plasmids in primary human myoblasts.
Gene therapy 2001;8(18):1387-94.
2001: Geoffrey Camirand; Nicolas J Caron; I Asselin; Jacques P Tremblay
Combined immunosuppression of mycophenolate mofetil and FK506 for myoblast transplantation in mdx mice.
Transplantation 2001;72(1):38-44.
2001: Jean-Thomas Vilquin; PF Kennel; Marion Paturneau-Jouas; Pierre Chapdelaine; N Boissel; P Delaère; Jacques P Tremblay; Daniel Scherman; Marc Fiszman; Ketty Schwartz
Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies.
Gene therapy 2001;8(14):1097-107.
2001: PA Moisset; Jacques P Tremblay
Gene therapy: a strategy for the treatment of inherited muscle diseases?
Current opinion in pharmacology 2001;1(3):294-9.
2001: Nicolas J Caron; Yvan Torrente; Geoffrey Camirand; M Bujold; Pierre Chapdelaine; K Leriche; N Bresolin; Jacques P Tremblay
Intracellular delivery of a Tat-eGFP fusion protein into muscle cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(3):310-8.
2001: Yvan Torrente; Jacques P Tremblay; Federica Pisati; Marzia Belicchi; Barbara Rossi; Manuela Sironi; Francesco Fortunato; elmostafa El fahime; Maria Grazia D'Angelo; Nicolas J Caron; Gabriela Constantin; D Paulin; Guglielmo Scarlato; Nereo Bresolin
Intraarterial injection of muscle-derived CD34(+)Sca-1(+) stem cells restores dystrophin in mdx mice.
The Journal of cell biology 2001;152(2):335-48.
2001: Jacques P Tremblay; J T Vilquin
[Transplantation of normal or genetically modified myoblasts for the treatment of hereditary or acquired diseases].
Journal de la Société de biologie 2001;195(1):29-37.
2000: Pierre Chapdelaine; PA Moisset; Philippe Campeau; I Asselin; Jean-Thomas Vilquin; Jacques P Tremblay
Functional EGFP-dystrophin fusion proteins for gene therapy vector development.
Protein engineering 2000;13(9):611-5.
2000: elmostafa El fahime; Yvan Torrente; Nicolas J Caron; M D Bresolin; Jacques P Tremblay
In vivo migration of transplanted myoblasts requires matrix metalloproteinase activity.
Experimental cell research 2000;258(2):279-87.
2000: Yvan Torrente; elmostafa El fahime; Nicolas J Caron; Nereo Bresolin; Jacques P Tremblay
Intramuscular migration of myoblasts transplanted after muscle pretreatment with metalloproteinases.
Cell transplantation 2000;9(4):539-49.
2000: PA Moisset; L Bonham; Daniel Skuk; DD Koeberl; V Brussee; Marlyne Goulet; Brigitte Roy; I Asselin; A Dusty Miller; Jacques P Tremblay
Systemic production of human granulocyte colony-stimulating factor in nonhuman primates by transplantation of genetically modified myoblasts.
Human gene therapy 2000;11(9):1277-88.
2000: Sophie Seigneurin-Venin; V Bernard; PA Moisset; M M Ouellette; Vincent Mouly; Silvia Di Donna; W E Wright; Jacques P Tremblay
Transplantation of normal and DMD myoblasts expressing the telomerase gene in SCID mice.
Biochemical and biophysical research communications 2000;272(2):362-9.
2000: Sophie Seigneurin-Venin; V Bernard; Jacques P Tremblay
Telomerase allows the immortalization of T antigen-positive DMD myoblasts: a new source of cells for gene transfer application.
Gene therapy 2000;7(7):619-23.
2000: Daniel Skuk; Marlyne Goulet; Brigitte Roy; Jacques P Tremblay
Myoblast transplantation in whole muscle of nonhuman primates.
Journal of neuropathology and experimental neurology 2000;59(3):197-206.
2000: Daniel Skuk; Jacques P Tremblay
Progress in myoblast transplantation: a potential treatment of dystrophies.
Microscopy research and technique 2000;48(3-4):213-22.
2000: Jean-Thomas Vilquin; Nicolas Vignier; Jacques P Tremblay; Eva Engvall; Ketty Schwartz; Marc Fiszman
Identification of homozygous and heterozygous dy2J mice by PCR.
Neuromuscular disorders : NMD 2000;10(1):59-62.
1999: Nicolas J Caron; I Asselin; G Morel; Jacques P Tremblay
Increased myogenic potential and fusion of matrilysin-expressing myoblasts transplanted in mice.
Cell transplantation 1999;8(5):465-76.
1999: Daniel Skuk; Denis Furling; Jean-Pierre Bouchard; Marlyne Goulet; Brigitte Roy; Y Lacroix; Jean-Thomas Vilquin; Jacques P Tremblay; Jack Puymirat
Transplantation of human myoblasts in SCID mice as a potential muscular model for myotonic dystrophy.
Journal of neuropathology and experimental neurology 1999;58(9):921-31.
1999: Nicolas J Caron; Pierre Chapdelaine; Jacques P Tremblay
Male-specific competitive PCR for the quantification of transplanted cells in mice.
BioTechniques 1999;27(3):424-6, 428.
1999: V Brussee; F Tardif; Brigitte Roy; Marlyne Goulet; A Sebille; Jacques P Tremblay
Successful myoblast transplantation in fibrotic muscles: no increased impairment by the connective tissue.
Transplantation 1999;67(12):1618-22.
1999: Jean-Thomas Vilquin; Benoit Guérette; Jack Puymirat; D Yaffe; F M Tomé; M Fardeau; Marc Fiszman; Ketty Schwartz; Jacques P Tremblay
Myoblast transplantations lead to the expression of the laminin alpha 2 chain in normal and dystrophic (dy/dy) mouse muscles.
Gene therapy 1999;6(5):792-800.
1999: Daniel Skuk; Brigitte Roy; Marlyne Goulet; Jacques P Tremblay
Successful myoblast transplantation in primates depends on appropriate cell delivery and induction of regeneration in the host muscle.
Experimental neurology 1999;155(1):22-30.
1998: PA Moisset; Y Gagnon; G Karpati; Jacques P Tremblay
Expression of human dystrophin following the transplantation of genetically modified mdx myoblasts.
Gene therapy 1998;5(10):1340-6.
1998: V Brussee; F Merly; F Tardif; Jacques P Tremblay
Normal myoblast implantation in MDX mice prevents muscle damage by exercise.
Biochemical and biophysical research communications 1998;250(2):321-7.
1998: Daniel Skuk; Jacques P Tremblay
Complement deposition and cell death after myoblast transplantation.
Cell transplantation 1998;7(5):427-34.
1998: C Huard; PA Moisset; A Dicaire; F Merly; F Tardif; I Asselin; Jacques P Tremblay
Transplantation of dermal fibroblasts expressing MyoD1 in mouse muscles.
Biochemical and biophysical research communications 1998;248(3):648-54.
1998: PA Moisset; Daniel Skuk; I Asselin; Marlyne Goulet; Brigitte Roy; G Karpati; Jacques P Tremblay
Successful transplantation of genetically corrected DMD myoblasts following ex vivo transduction with the dystrophin minigene.
Biochemical and biophysical research communications 1998;247(1):94-9.
1998: Jean-Thomas Vilquin; V Brussee; I Asselin; I Kinoshita; M Gingras; Jacques P Tremblay
Evidence of mdx mouse skeletal muscle fragility in vivo by eccentric running exercise.
Muscle & nerve 1998;21(5):567-76.
1998: H Ito; Jean-Thomas Vilquin; Daniel Skuk; Brigitte Roy; Marlyne Goulet; S Lille; Francine J Dugré; I Asselin; Raynald Roy; M Fardeau; Jacques P Tremblay
Myoblast transplantation in non-dystrophic dog.
Neuromuscular disorders : NMD 1998;8(2):95-110.
1998: F Merly; C Huard; I Asselin; P D Robbins; Jacques P Tremblay
Anti-inflammatory effect of transforming growth factor-beta1 in myoblast transplantation.
Transplantation 1998;65(6):793-9.
1998: H Ito; Patricia L Hallauer; Kenneth E M Hastings; Jacques P Tremblay
Prior culture with concanavalin A increases intramuscular migration of transplanted myoblast.
Muscle & nerve 1998;21(3):291-7.
1998: I Kinoshita; Jean-Thomas Vilquin; I Asselin; J Chamberlain; Jacques P Tremblay
Transplantation of myoblasts from a transgenic mouse overexpressing dystrophin prduced only a relatively small increase of dystrophin-positive membrane.
Muscle & nerve 1998;21(1):91-103.
1997: V Brussee; F Tardif; Jacques P Tremblay
Muscle fibers of mdx mice are more vulnerable to exercise than those of normal mice.
Neuromuscular disorders : NMD 1997;7(8):487-92.
1997: Benoit Guérette; Daniel Skuk; F Célestin; C Huard; F Tardif; I Asselin; Brigitte Roy; Marlyne Goulet; Raynald Roy; M Entman; Jacques P Tremblay
Prevention by anti-LFA-1 of acute myoblast death following transplantation.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2522-31.
1997: Benoit Guérette; PA Moisset; C Huard; F Tardif; C Gravel; Jacques P Tremblay
Inflammatory damage following first-generation replication-defective adenovirus controlled by anti-LFA-1.
Journal of leukocyte biology 1997;61(4):533-8.
1997: A Boulanger; I Asselin; Raynald Roy; Jacques P Tremblay
Role of non-major histocompatibility complex antigens in the rejection of transplanted myoblasts.
Transplantation 1997;63(6):893-9.
1997: Terence A Partridge; Jonathan R Beauchamp; J Morgan; Jacques P Tremblay; J Huard; Diana J Watt; Anton Wernig; Andrey Irintchev; M Grounds; M L Springer; R J Bartlett; J Mendell; J T Vilquin; J J Bower
Meeting of the Cell Transplantation Society in Miami.
Cell transplantation 1997;6(2):195-8.
1997: Benoit Guérette; I Asselin; Daniel Skuk; M Entman; Jacques P Tremblay
Control of inflammatory damage by anti-LFA-1: increase success of myoblast transplantation.
Cell transplantation 1997;6(2):101-7.
1996: B Guerette; M Gingras; K Wood; Raynald Roy; Jacques P Tremblay
Immunosuppression with monoclonal antibodies and CTLA4-Ig after myoblast transplantation in mice.
Transplantation 1996;62(7):962-7.
1996: Benoit Guérette; Jean-Thomas Vilquin; M Gingras; C Gravel; K J Wood; Jacques P Tremblay
Prevention of immune reactions triggered by first-generation adenoviral vectors by monoclonal antibodies and CTLA4Ig.
Human gene therapy 1996;7(12):1455-63.
1996: Benoit Guérette; G Tremblay; Jean-Thomas Vilquin; I Asselin; M Gingras; Raynald Roy; Jacques P Tremblay
Increased interferon-gamma mRNA expression following alloincompatible myoblast transplantation is inhibited by FK506.
Muscle & nerve 1996;19(7):829-35.
1996: I Kinoshita; R Roy; F J Dugré; C Gravel; Brigitte Roy; Marlyne Goulet; I Asselin; Jacques P Tremblay
Myoblast transplantation in monkeys: control of immune response by FK506.
Journal of neuropathology and experimental neurology 1996;55(6):687-97.
1996: I Kinoshita; Jean-Thomas Vilquin; R Roy; Jacques P Tremblay
Successive injections in mdx mice of myoblasts grown with bFGF.
Neuromuscular disorders : NMD 1996;6(3):187-93.
1996: Jean-Thomas Vilquin; I Kinoshita; Brigitte Roy; Marlyne Goulet; E Engvall; F Tomé; M Fardeau; Jacques P Tremblay
Partial laminin alpha2 chain restoration in alpha2 chain-deficient dy/dy mouse by primary muscle cell culture transplantation.
The Journal of cell biology 1996;133(1):185-97.
1996: I Kinoshita; Jean-Thomas Vilquin; Jacques P Tremblay
Mechanism of increasing dystrophin-positive myofibers by myoblast transplantation: study using mdx/beta-galactosidase transgenic mice.
Acta neuropathologica 1996;91(5):489-93.
1995: Benoit Guérette; Raynald Roy; M Tremblay; I Asselin; I Kinoshita; J Puymirat; Jacques P Tremblay
Increased granzyme B mRNA after alloincompatible myoblast transplantation.
Transplantation 1995;60(9):1011-6.
1995: Jean-Thomas Vilquin; I Kinoshita; R Roy; Jacques P Tremblay
Cyclophosphamide immunosuppression does not permit successful myoblast allotransplantation in mouse.
Neuromuscular disorders : NMD 1995;5(6):511-7.
1995: Jean-Thomas Vilquin; Benoit Guérette; I Kinoshita; B Roy; Marlyne Goulet; C Gravel; Raynald Roy; Jacques P Tremblay
FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer.
Human gene therapy 1995;6(11):1391-401.
1995: Jean-Thomas Vilquin; E Wagner; I Kinoshita; R Roy; Jacques P Tremblay
Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin.
The Journal of cell biology 1995;131(4):975-88.
1995: I Kinoshita; Jean-Thomas Vilquin; C Gravel; Raynald Roy; Jacques P Tremblay
Myoblast allotransplantation in primates.
Muscle & nerve 1995;18(10):1217-8.
1995: I Asselin; M Tremblay; Jean-Thomas Vilquin; Benoit Guérette; Raynald Roy; Jacques P Tremblay
Quantification of normal dystrophin mRNA following myoblast transplantation in mdx mice.
Muscle & nerve 1995;18(9):980-6.
1995: I Kinoshita; Jean-Thomas Vilquin; Jacques P Tremblay
Pretreatment of myoblast cultures with basic fibroblast growth factor increases the efficacy of their transplantation in mdx mice.
Muscle & nerve 1995;18(8):834-41.
1995: Jean-Thomas Vilquin; I Asselin; Benoit Guérette; I Kinoshita; Raynald Roy; Jacques P Tremblay
Successful myoblast allotransplantation in mdx mice using rapamycin.
Transplantation 1995;59(3):422-6.
1995: Benoit Guérette; I Asselin; Jean-Thomas Vilquin; Raynald Roy; Jacques P Tremblay
Lymphocyte infiltration following allo- and xenomyoblast transplantation in mdx mice.
Muscle & nerve 1995;18(1):39-51.
1994: Benoit Guérette; I Asselin; Jean-Thomas Vilquin; Raynald Roy; Jacques P Tremblay
Lymphocyte infiltration following allo- and xenomyoblast transplantation in mice.
Transplantation proceedings 1994;26(6):3461-2.
1994: Jean-Thomas Vilquin; I Asselin; Benoit Guérette; I Kinoshita; S Lille; Raynald Roy; Jacques P Tremblay
Myoblast allotransplantation in mice: degree of success varies depending on the efficacy of various immunosuppressive treatments.
Transplantation proceedings 1994;26(6):3372-3.
1994: I Kinoshita; Jean-Thomas Vilquin; Benoit Guérette; I Asselin; Raynald Roy; S Lille; Jacques P Tremblay
Immunosuppression with FK 506 insures good success of myoblast transplantation in MDX mice.
Transplantation proceedings 1994;26(6):3518.
1994: I Asselin; M Tremblay; Jean-Thomas Vilquin; Benoit Guérette; Jacques P Tremblay
Polymerase chain reaction-based assay to assess the success of myoblast transplantation in mdx mice.
Transplantation proceedings 1994;26(6):3389.
1994: I Kinoshita; Jean-Thomas Vilquin; Benoit Guérette; I Asselin; Raynald Roy; Jacques P Tremblay
Very efficient myoblast allotransplantation in mice under FK506 immunosuppression.
Muscle & nerve 1994;17(12):1407-15.
1994: I Kinoshita; J Huard; Jacques P Tremblay
Utilization of myoblasts from transgenic mice to evaluate the efficacy of myoblast transplantation.
Muscle & nerve 1994;17(9):975-80.
1994: J Huard; Raynald Roy; Benoit Guérette; S Verreault; G Tremblay; Jacques P Tremblay
Human myoblast transplantation in immunodeficient and immunosuppressed mice: evidence of rejection.
Muscle & nerve 1994;17(2):224-34.
1994: J Huard; S Verreault; Raynald Roy; M Tremblay; Jacques P Tremblay
High efficiency of muscle regeneration after human myoblast clone transplantation in SCID mice.
The Journal of clinical investigation 1994;93(2):586-99.
1993: A Satoh; J Huard; C Labrecque; Jacques P Tremblay
Use of fluorescent latex microspheres (FLMs) to follow the fate of transplanted myoblasts.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1993;41(10):1579-82.
1993: Jacques P Tremblay; J P Bouchard; F Malouin; D Théau; F Cottrell; H Collin; A Rouche; S Gilgenkrantz; N Abbadi; M Tremblay
Myoblast transplantation between monozygotic twin girl carriers of Duchenne muscular dystrophy.
Neuromuscular disorders : NMD 1993;3(5-6):583-92.
1993: Jacques P Tremblay; F Malouin; Raynald Roy; J Huard; Jean-Pierre Bouchard; A Satoh; Carol L Richards
Results of a triple blind clinical study of myoblast transplantations without immunosuppressive treatment in young boys with Duchenne muscular dystrophy.
Cell transplantation 1993;2(2):99-112.
1993: J Huard; G Tremblay; S Verreault; C Labrecque; Jacques P Tremblay
Utilization of an antibody specific for human dystrophin to follow myoblast transplantation in nude mice.
Cell transplantation 1993;2(2):113-8.
1993: Raynald Roy; Jacques P Tremblay; J Huard; C Richards; F Malouin; Jean-Pierre Bouchard
Antibody formation after myoblast transplantation in Duchenne-dystrophic patients, donor HLA compatible.
Transplantation proceedings 1993;25(1 Pt 2):995-7.
1993: M Belles-Isles; Raynald Roy; G Dansereau; Marlyne Goulet; Brigitte Roy; Jean-Pierre Bouchard; Jacques P Tremblay
Rapid selection of donor myoblast clones for muscular dystrophy therapy using cell surface expression of NCAM.
European journal of histochemistry : EJH 1993;37(4):375-80.
1992: J Huard; Raynald Roy; Jean-Pierre Bouchard; F Malouin; Carol L Richards; Jacques P Tremblay
Human myoblast transplantation between immunohistocompatible donors and recipients produces immune reactions.
Transplantation proceedings 1992;24(6):3049-51.
1992: A Satoh; C Labrecque; Jacques P Tremblay
Myotubes can be formed within implanted adipose tissue.
Transplantation proceedings 1992;24(6):3017-9.
1992: C Labrecque; Raynald Roy; Jacques P Tremblay
Immune reactions after myoblast transplantation in mouse muscles.
Transplantation proceedings 1992;24(6):2889-92.
1992: N Albert; Jacques P Tremblay
Evaluation of various gene transfection methods into human myoblast clones.
Transplantation proceedings 1992;24(6):2784-6.
1992: J Huard; P Y Côté; A Parent; Jean-Pierre Bouchard; Jacques P Tremblay
Dystrophin-like immunoreactivity in monkey and human brain areas involved in learning and motor functions.
Neuroscience letters 1992;141(2):181-6.
1992: J Huard; Jean-Pierre Bouchard; Raynald Roy; F Malouin; G Dansereau; C Labrecque; N Albert; Carol L Richards; B Lemieux; Jacques P Tremblay
Human myoblast transplantation: preliminary results of 4 cases.
Muscle & nerve 1992;15(5):550-60.
1992: J Huard; Jacques P Tremblay
Localization of dystrophin in the Purkinje cells of normal mice.
Neuroscience letters 1992;137(1):105-8.
1992: J Huard; L P Fortier; G Dansereau; C Labrecque; Jacques P Tremblay
A light and electron microscopic study of dystrophin localization at the mouse neuromuscular junction.
Synapse (New York, N.Y.) 1992;10(2):83-93.
1992: J Huard; A Satoh; Jacques P Tremblay
Mosaic expression of dystrophin in the cerebellum of heterozygote dystrophic (mdx) mice.
Neuromuscular disorders : NMD 1992;2(5-6):311-21.
1991: C Labrecque; J Huard; G Dansereau; N Albert; Jacques P Tremblay
In vitro bromodeoxyuridine labeling of nuclei: application to myotube hybridization.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991;39(10):1421-6.
1991: J Huard; Jean-Pierre Bouchard; Raynald Roy; C Labrecque; G Dansereau; B Lemieux; Jacques P Tremblay
Myoblast transplantation produced dystrophin-positive muscle fibres in a 16-year-old patient with Duchenne muscular dystrophy.
Clinical science (London, England : 1979) 1991;81(2):287-8.
1991: J Huard; L P Fortier; C Labrecque; G Dansereau; Jacques P Tremblay
Is dystrophin present in the nerve terminal at the neuromuscular junction? An immunohistochemical study of the heterozygote dystrophic (mdx) mouse.
Synapse (New York, N.Y.) 1991;7(2):135-40.
1991: J Huard; C Labrecque; G Dansereau; L Robitaille; Jacques P Tremblay
Dystrophin expression in myotubes formed by the fusion of normal and dystrophic myoblasts.
Muscle & nerve 1991;14(2):178-82.
1991: Raynald Roy; G Dansereau; Jacques P Tremblay; M Belles-Isles; J Huard; C Labrecque; Jean-Pierre Bouchard
Expression of major histocompatibility complex antigens on human myoblasts.
Transplantation proceedings 1991;23(1 Pt 1):799-801.
1991: Jacques P Tremblay; B Roy; M Goulet
Human myoblast transplantation: a simple assay for tumorigenicity.
Neuromuscular disorders : NMD 1991;1(5):341-3.
1991: C Labrecque; J Huard; G Dansereau; L Robitaille; Jacques P Tremblay
A new technique to identify hybrid myotubes in vitro without culture fixation.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991;39(1):139-43.
1991: R Robitaille; Jacques P Tremblay
Non-uniform responses to Ca2+ along the frog neuromuscular junction: effects on the probability of spontaneous and evoked transmitter release.
Neuroscience 1991;40(2):571-85.
1990: L P Fortier; Jacques P Tremblay
Postsynaptic structure may account for variations in miniature endplate current shapes along frog neuromuscular junctions.
Synapse (New York, N.Y.) 1990;5(4):255-64.
1989: Jacques P Tremblay; R Robitaille; O Martineau; C Labrecque; M A Fahim
Proximodistal gradients of the postjunctional folds at the frog neuromuscular junction: a scanning electron microscopic study.
Neuroscience 1989;30(2):535-50.
1988: C Labrecque; Jacques P Tremblay; M A Fahim
Scanning electron microscopic study of the neuromuscular junction of dystrophic mice.
Experimental neurology 1988;100(1):51-64.
1988: Jacques P Tremblay; L Grégoire; R Sasseville; G Guay; C Belhumeur
Reduction of postjunctional fold density and depth in dystrophic mice.
Synapse (New York, N.Y.) 1988;2(2):148-56.
1987: Jacques P Tremblay; L Grégoire; R Sasseville; C Belhumeur
Repeated stimulation of the dystrophic mouse neuromuscular junctions.
Muscle & nerve 1987;10(4):303-11.
1986: C Belhumeur; Jacques P Tremblay
Fast turnover of clear vesicle membrane in frog sympathetic ganglion.
Neuroscience 1986;17(4):1267-74.
1986: Jacques P Tremblay; C Belhumeur; R Sasseville; L Grégoire
Non monotonic morphometric changes produced at mouse neuromuscular junctions following in vivo stimulation at various frequencies.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1986;61(3):638-44.